Search | Preprints.org

Preprint ARTICLE | doi:10.20944/preprints202308.0307.v1

The Consistency of the Distribution Function Conditional Estimate and Application on the Consistency and Asymptotic Normality of the Conditional Hazard Function Estimate for High Dimensional Quasi-Associated Data

Hamza Daoudi, Zouaoui Chikr Elmezouar, Fatimah Alshahrani

Subject: Computer Science And Mathematics, Mathematics Keywords: conditional distribution function; asymptotic normality, conditionalhazard function; quasi-associated; functional data

Online: 3 August 2023 (10:53:17 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202202.0100.v1

Quasi-Degree in Neutrosophic Graphs

Henry Garrett

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Quasi-Co-Degree; Quasi-Degree; Vertex

Online: 7 February 2022 (16:23:20 CET)

Show abstract| Download PDF| Share

New setting is introduced to study quasi-degree and quasi-co-degree arising from co-neighborhood. quasi-degree and quasi-co-degree is about a vertex which are applied into the setting of neutrosophic graphs. . The structure of set is studied and general results are obtained. Also, some classes of neutrosophic graphs namely path-neutrosophic graphs, cycle-neutrosophic graphs, complete-neutrosophic graphs and star-neutrosophic graphs, complete-bipartite-neutrosophic graphs and complete-multipartite-neutrosophic graphs are investigated in the terms of a vertex which is called either quasi-degree or quasi-co-degree. Neutrosophic number is reused in this way. It’s applied to use the type of neutrosophic number in the way that, three values of a vertex are used and they’ve same share to construct this number to compare with other vertices. Summation of three values of vertex makes one number and applying it to a comparison. This approach facilitates identifying vertices which form quasi-degree and quasi-co-degree. Quasi-degree is a value of a vertex which is maximum amid all values of vertices which are neighbors to a fixed vertex. Quasi-co-degree is a value of an edge which is maximum amid all values of edges which are neighbors to a fixed vertex but corresponded vertex is representative for this notion. Using different values which are related to a vertex inspire us to focus on edge and vertices which are corresponded to a fixed vertex. The notion of neighborhood is used to collect either vertices are titled neighbors or edges are incident to fixed vertex. In both settings, some classes of well-known neutrosophic graphs are studied. Some clarifications for each result and each definitions are provided. Using fixed vertex has key role to have these notions in the form of vertex or edge. The value of an edge has eligibility to call quasi-co-degree but the value of a vertex has eligibility to call quasi-degree. Some results get more frameworks and perspective about these definitions. The way in that, two vertices have connection together, open the way to define neighborhood and co-neighborhood. The maximum values in neighborhood and co-neighborhood introduces quasi-degree and quasi-co-degree, respectively. New name is chosen from degree. Since amid all vertices with different degrees, one vertex is chosen. In other words, one vertex is fixed and its degree turns out quasi-degree where two degrees could be assigned to a vertex. Degree of edges and degree of vertices. The number of edges which are incident to the vertex and the number of vertices which are neighbors to the vertex. Degree and co-degree are the notions which are transformed to use in quasi-style. Two neutrosophic values introduce two neutrosophic vertices separately in each settings. These notions are applied into neutrosophic graphs as individuals but not family of them as drawbacks for these notions. Finding special neutrosophic graphs which are well-known, is an open way to purse this study. Some problems are proposed to pursue this study. Basic familiarities with graph theory and neutrosophic graph theory are proposed for this article.

Preprint ARTICLE | doi:10.20944/preprints202203.0248.v1

Some Results in Classes Of Neutrosophic Graphs

Henry Garrett

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Neutrosophic Quasi-Order; Neutrosophic Quasi-Size; Neutrosophic Quasi-Number; Neutrosophic Quasi-Co-Number; Neutrosophic Co-t-Neighborhood

Online: 17 March 2022 (08:48:38 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202402.1321.v1

Integration of GNSS Technology and Geometric Levelling for Accurate Height Determination in Uneven Terrains: A Case Study in Lebanon

Murat Mustafin, And Hiba Moussa

Subject: Engineering, Civil Engineering Keywords: EGM2008; GNSS; levelling; quasi-geoid height

Online: 22 February 2024 (16:09:23 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201811.0473.v1

The Quasi Steady State Cosmology in a Radiation Dominated Phase

Raj Bali

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: Quasi Steady State Cosmology, Radiation Phase

Online: 19 November 2018 (16:48:10 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.1477.v1

The Strong Ekeland Variational Principle in Quasi-Pseudometric Spaces

Stefan Cobzas

Subject: Computer Science And Mathematics, Geometry And Topology Keywords: quasi-metric space; completeness in quasi-metric spaces; variational principles; Ekeland variational principle; strong Ekeland principle

Online: 20 December 2023 (12:18:48 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202403.0944.v1

An Enhanced Particle Swarm Optimization (PSO) Employing Quasi-Random Numbers

Shivakumar Kannan, Urmila Diwekar

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: Enhanced PSO; SOBOL; Halton; Quasi-random numbers

Online: 15 March 2024 (16:00:41 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202104.0283.v2

The Seasonal Variability of the Ocean Energy Cycle From a Quasi-Geostrophic Double Gyre Ensemble

Takaya Uchida, Bruno Deremble, Thierry Penduff

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Ocean circulation; Geostrophic turbulence; Quasi-geostrophic flows

Online: 26 May 2021 (13:03:28 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202309.0917.v1

Accelerating Quantum Decay by Multiple Tunneling Barriers

Stefano Longhi, Ermanno Pinotti

Subject: Physical Sciences, Quantum Science And Technology Keywords: quantum tunneling; quasi bound states; tight binding lattices

Online: 14 September 2023 (03:42:42 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202212.0311.v1

Observed Quasi 16-Day Wave by Meteor Radar Over 9 Years at Mengcheng (33.4°N, 116.5°E) and Comparison with the WACCM Simulation

Chengyun Yang, Dexin Lai, Wen Yi, Jianfei Wu, Xianghui Xue, Tao Li, Tingdi Chen, Xiankang Dou

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: meteor radar; quasi 16-day wave; mesospheric dynamics

Online: 19 December 2022 (02:51:19 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202203.0381.v1

Rossby Waves in Total Ozone over the Arctic in 2000–2021

Chenning Zhang, Asen Grytsai, Oleksandr Evtushevsky, Gennadi Milinevsky, Yulia Andrienko, Valery Shulga, Andrew Klekociuk, Yuriy Rapoport, Wei Han

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Rossby wave; quasi-stationary wave; stratosphere; Arctic; ozone

Online: 29 March 2022 (11:26:45 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201905.0371.v1

Thermodynamic, non-extensive, or turbulent quasi equilibrium for space plasma environment

Peter Yoon

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: non-extensive entropic principle; plasma turbulence; quasi equilibrium

Online: 31 May 2019 (06:12:02 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.1669.v1

Effects of Probiotics in Elderly Hospitalized Tube-Fed Patients with Antibiotic Use

Chu-Hsuan Hsia, Hsiu-Yueh Su, Yue-Hwa Chen, Han-Chuan Chuang, Yi-wen Chien

Subject: Biology And Life Sciences, Aging Keywords: Antibiotic-associated diarrhea (AAD); Clostridium difficile-associated diarrhea (CDAD); Probiotic; Tube-fed elderly; Infectious disease

Online: 27 November 2023 (10:22:14 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202310.0451.v1

Analyzing the Robustness of Complex Networks with Attack Success Rate

Fangqun Yang, Yisong Wang

Subject: Computer Science And Mathematics, Other Keywords: complex network; robustness; quasi-Monte Carlo; attack success rate

Online: 9 October 2023 (11:37:39 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.1629.v1

Scaled-Invariant Extended Quasi-Lindley Model: Properties, Estimation and Application

Mohamed Kayid, Abdulrahman Abouammoh, Ghadah Alomani

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: Quasi Lindley model; maximum likelihood estimator; expectation maximization algorithm

Online: 25 July 2023 (03:08:48 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202303.0485.v1

Thermal Fluctuations of Torus-like Charge AdS Black Hole

R. H. Ali, G. Abbas

Subject: Physical Sciences, Thermodynamics Keywords: Thermodynamics; Thermal fluctuation; Phase transition and Quasi normal modes

Online: 28 March 2023 (10:27:31 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202105.0548.v1

Deterministic Model of the Eddy Dynamics for a Midlatitude Ocean Model

Takaya Uchida, Bruno Deremble, Stephane Popinet

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Mesoscale eddy closure; Quasi geostrophy; Mid-latitude double gyre

Online: 24 May 2021 (09:37:26 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201909.0073.v1

Quasi-stationary Strength of ECAP-processed Cu-Zr at 0.5Tm

Wolfgang Blum, Jiri Dvorak, Petr Kral, Philip Eisenlohr, Vaclav Sklenicka

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Cu-Zr; ECAP; deformation; quasi-stationary; subgrains; grains; coarsening

Online: 6 September 2019 (12:15:47 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201806.0041.v1

Hybrid PV-Wind Micro-Grid Development Using Quasi-Z-Source Inverter Modeling and Control –Experimental Investigation

Neeraj Priyadarshi, Sanjeevikumar Padmanaban, Dan M. Ionel, Lucian Mihet-Popa, Farooque Azam

Subject: Engineering, Electrical And Electronic Engineering Keywords: PV; MPRVS; quasi Z-source inverter; MPP; SEPIC converter

Online: 4 June 2018 (12:19:02 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202403.1264.v1

Prevalence of Condom Use and Associated Factors among Undergraduate Students of Gulu University.

Brian Otim, Jerom Okot, Ritah Nantale, Winnie Kibone, Grace Madraa, Christopher Okot, Felix Bongomin

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Undergraduates; condom use; associated factors; Uganda

Online: 21 March 2024 (08:55:54 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202402.0220.v1

Beyond Quiescent and Active: Intermediate Microglial Transcriptomic States in a Mouse Model of Down Syndrome

Álvaro Fernández-Blanco, Cèsar Sierra, Clara Tejido, Mara Dierssen

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: Down syndrome; microglia; disease-associated microglia

Online: 5 February 2024 (05:38:38 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202401.1831.v1

COVID-19 Vaccine Coverage and Factors Associated with Vaccine Hesitancy: A Cross-Sectional Survey in the City of Kinshasa, Democratic Republic of Congo

Pierre Z Akilimali, Landry Egbende, Dynah M Kayembe, Francis Kabasubabo, Benito Kazenza, Steve Botomba, Nguyen Toan Tran, Désiré Kulimba Mashinda

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: COVID-19; vaccine hesitancy; associated factors

Online: 26 January 2024 (02:07:33 CET)

Show abstract| Download PDF| Share

: Background: Vaccination against COVID-19 has been the main strategy used by most countries to limit the spread of the virus. However, vaccine uptake has been low in Africa, leading to the implementation of several interventions in order to improve vaccine coverage. This study was conducted due to the lack of information about COVID-19 vaccine coverage and the factors associated with vaccine hesitancy. Methods: This cross-sectional study was carried out in Kinshasa city using multi-stage random sampling. A total of 2160 households were included in the study. The data were analyzed using Stata 15 software. The means and standard deviations were calculated for normally distributed continuous variables, while proportions with their 95% confidence intervals (CIs) were calculated for categorical variables. Pearson’s chi-square test or Fisher’s exact test was used to test the associations between dependent variables and each independent variable. Logistic regression was used to identify the factors associated with hesitancy receiving the COVID-19 vaccination. Results: The majority of respondents were aged between 25 and 34 and 35 and 49 (28.9%). During this study, 15% (95% CI [13.25–17.9]) of respondents had received at least one dose of the COVID-19 vaccine. Among the reasons given for refusing to be vaccinated, most respondents cited concerns about the vaccine being unsafe or causing adverse reactions (45%). Among the reasons given for accepting the vaccine, 26% thought that the vaccine prevented superinfection. The factors associated with hesitancy toward the COVID-19 vaccine were female gender, an age of less than 35 years, and living in non-slum households. Conclusions: Despite the interventions implemented across the country, the reluctance to be vaccinated remains a problem; this could lead to poor health outcomes, especially among the elderly and those with pre-existing conditions. It is important to step up awareness-raising campaigns in the community in order to increase the uptake of vaccination.

Preprint ARTICLE | doi:10.20944/preprints202309.1004.v1

MicroRNAs Signature Set Identifies Heavy Drinkers with Alcohol-associated Cirrhosis from those Without Liver Injury

Fathima Shihana, Mugdha V. V Joglekar, Tae Hwi Linus Schwantes-An, Anandwardhan Hardikar, Devanshi Seth

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: alcohol-associated liver cirrhosis; microRNAs; biomarker

Online: 15 September 2023 (03:31:18 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Background: Alcohol-associated Liver Disease (ALD) is the most common disorder of prolonged drinking. Mechanisms underlying cirrhosis in such patients remain unclear. MicroRNAs play regulatory role in several diseases, are affected by alcohol and may be important players in alcohol use disorders, such as cirrhosis. Methods: We investigated serum samples from heavy chronic alcohol users (80g/d (M) and 50g/d (F) for ≥10 years) that were available from our previously reported GenomALC study. A subset of drinkers with liver cirrhosis (cases, n=24) and those without significant liver disease (controls, n=23) were included. Healthy controls (HC, n=5) were volunteers in the study. Global microRNA profiling was performed using high-throughput real-time quantitative PCR to identify the microRNA signatures. Ingenuity Pathway Analysis software (IPA) was utilized to identify target mRNAs of significantly altered microRNAs and molecular pathways were analysed. Identified microRNAs were analysed for correlation with traditional liver disease biomarkers and risk gene variants previously reported from GenomALC genome-wide association study. Results: The expression of 81 and 21 microRNAs was significantly downregulated in cases compared to HC and controls, respectively (p<0.05, Ct >1.5-fold). Most microRNAs showed lower abundance in alcohol users compared with HC. Seven microRNAs (miR-16, miR-19a, miR-27a, miR-29b, miR-101, miR-130a, & miR-191) had a highly significant correlation (p<0.001) with INR, bilirubin and MELD score. Three microRNAs (miR-27a, miR-130a and miR-191) significantly predicted cases with AUC-ROC 0.8, 0.78 and 0.85, respectively (P<0.020), however, INR performed best (0.97, p<0.001). A different set of 6 microRNAs (miR-19a, miR-26a, miR-101, miR-151-3p, miR-221, & miR-301) showed positive correlation (ranging 0.32-0.51, p<0.05) with rs10433937:HSD17B13 gene variant, associated with risk of cirrhosis. IPA analysis revealed mRNA targets of the significantly altered microRNAs associated with cell death/necrosis, fibrosis and increased steatosis, particularly triglyceride metabolism related mRNA targets. Conclusions: MicroRNA signatures in drinkers distinguished those with liver cirrhosis from those without liver disease. We identified mRNA targets in liver functions that were enriched for disease pathogenesis pathways.

Preprint CASE REPORT | doi:10.20944/preprints202306.2102.v1

Gordonia sputi as an Arising Causative Agent of Bacteremia in Immunocompromised Comorbid Dialysis Patients—A Case Report

Bozhidar Vergov, Andreana Angelova, Alexandra Baldzhieva, Yordan Kalchev, Georgi Tsochev, Marianna Murdjeva

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: Gordonia sputi; Dialysis; Catheter-associated infection

Online: 29 June 2023 (11:35:49 CEST)

Show abstract| Download PDF| Share

Preprint COMMUNICATION | doi:10.20944/preprints202112.0492.v1

Secondary Structure and X-Ray Crystallographic Analysis of the Glideosome-Associated Connector (GAC) from Toxoplasma gondii

Amit Kumar, Xu Zhang, Oscar Vadas, Fisentzos Stylianou, Nicolas Dos Santos Pacheco, Sarah Rouse, Marc Morgan, Dominique Soldati-Favre, Stephen Matthews

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: glideosome-associated connector; protein; crystallography; structure

Online: 30 December 2021 (17:13:26 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202404.0484.v1

On Approximate Variational Inequalities and Bilevel Programming Problems

Balendu Bhooshan Upadhyay, I. M. Stancu-Minasian, Subham Poddar, Priyanka Mishra

Subject: Computer Science And Mathematics, Mathematics Keywords: limiting subdifferentials; ϵ-quasi solutions; approximate convex functions; variational inequalities

Online: 8 April 2024 (16:35:51 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202402.1551.v1

In-Plane Mechanical Characterization of a Kevlar® Composite

Rene Alejandro Canceco-de la Cruz, Caleb Carreño-Gallardo, Alberto Diaz Díaz, Luis Adrian Zuñiga-Aviles, Gabriel Plascencia-Barrera, Jose Martin Herrera-Ramirez

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: Kevlar®; ; Polymer composite; Mechanical properties; Quasi-static tensile test

Online: 28 February 2024 (12:58:26 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202401.0328.v2

Dissipative Chaotic Itinerancy and the Dirichlet Eta Function

Hime Oliveira

Subject: Computer Science And Mathematics, Mathematics Keywords: Dirichlet Eta function; Samsara; Moksha; Quasi-attractor; Bifurcation; Chaotic Itinerancy

Online: 8 January 2024 (06:30:30 CET)

Show abstract| Download PDF| Share

This work presents a new type of chaotic dynamical system originated from Dirichlet Eta function. Although the exposition describes only a bidimensional instance, it is certainly possible to construct higher dimensional such models. The novelty resides in the multitude of interesting characteristics concentrated in only one kind of dynamical system, mainly because of its simple abstract definition - it provokes dissipative, chaotic and itinerant behavior, and its paths typically display nonrecurring quasi-attractors and associate regions of ruin. In addition, it is discrete and nonautonomous, being additively driven by a simple real vector sequence. Also, the defining formulas have parameters which permit to activate bifurcatory effects, mainly related to setting the number of quasi-attractors and overall geometric complexity and diversity. In this fashion, it holds a certain similarity with classical itinerant chaotic systems, but it is a completely different object. One of its parameters is very influential and may be intuitively compared to a type of "potential energy", capable of changing the duration of sojourns etc. In this fashion, there is a potential opportunity to employ artificial inference techniques for designing specific structures on paths. Of course, the other parameters are also relevant, but not necessarily in the control of the number of quasi-attractors and the permanence periods near them. It is important to state that the described system was found during a previous investigation about certain features of the Riemann hypothesis, using the Dirichlet Eta function instead of the Riemann Zeta function - the components of the system under study here were part of certain series whose convergence had to be established, and that scenario produced this very positive side effect. The text also suggests an atypical, but important, potential application in philosophy: the representation of the Hindu concepts of Samsara and Moksha.

Preprint ARTICLE | doi:10.20944/preprints202312.0038.v1

Experimental Study of Cold Dense Nuclear Matter

Maria Patsyuk, Timur Atovullaev, Goran Johansson, Dmitriy Klimanskiy, Vasilisa Lenivenko, Sergey Nepochatykh, Eli Piasetzky

Subject: Physical Sciences, Nuclear And High Energy Physics Keywords: quasi-elastic scattering; short-range correlations; cold dense nuclear matter

Online: 1 December 2023 (08:00:04 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202305.1113.v1

Hybrid Source Multi-Port Quasi-Z-Source Converter with Fuzzy Logic-Based Energy Management

Gorkem Say, Seyed Hossein Hosseini, Parvaneh Esmaili

Subject: Engineering, Electrical And Electronic Engineering Keywords: Energy Management; Quasi-Z-Source; Fuzzy Logic; DC-DC Converter

Online: 16 May 2023 (07:11:13 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202008.0505.v1

Applying the Cracking Elements Method for Analyzing the Damaging Processes of Structures with Fissures

Qianqian Dong, Jie Wu, Zizheng Sun, Xiao Yan, Yiming Zhang

Subject: Engineering, Mechanical Engineering Keywords: Quasi-brittle material; cracking elements method; Uni-axial compression tests

Online: 24 August 2020 (05:59:51 CEST)

Show abstract| Download PDF| Share

Working Paper ARTICLE

Completeness in Quasi-Pseudometric Spaces

Ştefan Cobzas

Subject: Computer Science And Mathematics, Geometry And Topology Keywords: quasi-pseudometric space; Cauchy sequence; Cauchy net; Cauchy filter; completeness

Online: 15 July 2020 (08:49:38 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202207.0175.v1

Orthogonal Frames in Krein Spaces

Osmin Oberto Ferrer Villar, Arley Yessit Sierra Acosta, Osvaldo De Jesus Polo Flórez

Subject: Computer Science And Mathematics, Analysis Keywords: Krein space; fundamental symmetry; Hilbert associated; frames

Online: 12 July 2022 (08:10:52 CEST)

Show abstract| Download PDF| Share

Preprint BRIEF REPORT | doi:10.20944/preprints202109.0015.v1

HIV Prevalence and Risk Factors for Infants Born to Mothers on Arv Treatment at CHUB/Rwanda

Bernard Nsengimana, Francois Nkurunziza, Wivine Mudahigwa Ntaganira, Ruth Uzayisenga, Gad Rutayisire

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Rwanda; Risk associated MTCT; HIV-exposed infants

Online: 1 September 2021 (12:18:07 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202106.0453.v1

How Well do European Patients Understand Cancer-Associated Thrombosis? A Patient Survey

Ismail Elalamy, Anna Falanga, Charis Girvalaki, Manuel Monreal, Jacob C. Easaw, Annie Young

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Cancer-associated thrombosis; survey; anticoagulant; cancer patients

Online: 17 June 2021 (09:17:59 CEST)

Show abstract| Download PDF| Share

Preprint CASE REPORT | doi:10.20944/preprints202008.0292.v1

Granulomatosis with Polyangiitis Restricted to The Back Muscle: The First Case Report

Yu-Mi Lee, Sang Wan Chung

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: ANCA-associated vasculitis; organ limited vasculitis; GPA

Online: 13 August 2020 (06:59:27 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202404.1766.v1

Quasi-Interpolation on Chebyshev Grids with Boundary Corrections

Faisal Alsharif

Subject: Computational Mathematics, Computer Science And Mathematics Keywords: Quasi-Interpolation; Radial basis functions; Boundary corrections; Chebyshev Points; Univariate Interpolation

Online: 26 April 2024 (11:52:07 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.0138.v1

Study of 6√3 Reconstruction Conversion on the of 4H-SiC(0001) Surface to Quasi-free Epitaxial Graphene with Electron Diffraction

Irina Sergeevna Kotousova, Sergey Pavlovich Lebedev, Vladimir Viktorovich Antipov, Alexander Alexandrovich Lebedev

Subject: Physical Sciences, Condensed Matter Physics Keywords: silicon carbide; RHEED; reconstruction; hydrogen intercalation; quasi-free single-layer graphene

Online: 2 June 2023 (10:03:28 CEST)

Show abstract| Download PDF| Share

Preprint COMMUNICATION | doi:10.20944/preprints202102.0425.v1

Perspectives on the Yang-Baxter Equation in Bck-Algebras

Florin Nichita, Tahsin Oner, Tugce KALKAN, Ibrahim Senturk, Mehmet Terziler

Subject: Computer Science And Mathematics, Mathematics Keywords: BCK-algebras; Yang-Baxter Equation; Quasi-negation operator; Boolean coalgebras; poetry

Online: 18 February 2021 (17:26:17 CET)

Show abstract| Download PDF| Share

Working Paper REVIEW

Nano-(Q)SAR for Cytotoxicity Prediction of Engineered Nanomaterials

Andrey A. Buglak, Anatoly V. Zherdev, Boris B. Dzantiev

Subject: Chemistry And Materials Science, Nanotechnology Keywords: engineered nanomaterials; safety of nanomaterials; toxicological tests; modeling; descriptors; quasi-qsar

Online: 31 October 2019 (09:38:45 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201811.0304.v1

Transversely Modulated Wave Packet

Vladimir N. Salomatov

Subject: Physical Sciences, Theoretical Physics Keywords: quasi-monochromatic waves; group velocity; dispersion relation; longitudinal modulation; coherence time

Online: 13 November 2018 (09:24:07 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201703.0138.v1

On Unsteady Three-Dimensional Axisymmetric MHD Nanofluid Flow with Entropy Generation and Thermo-Diffusion Effects

Mohammed Almakki, Sharadia Dey, Sabyasachi Mondal, Precious Sibanda

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Unsteady 3-D axisymmetric nanofluid; Entropy generation; Spectral quasi-linearization method.

Online: 17 March 2017 (15:10:32 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202209.0475.v1

A Retrospective, Observational Study of Catheter-associated Urinary Tract Infection Events Post-implementation of a Novel Urinary Catheter System with Active Drain Line Clearance and Automated Intra-abdominal Pressure Monitoring

Patrick Brockway, David M. Hill, Vanessa Moll, Kelly Stanton, Manu L.N.G. Malbrain, Sai R. Velamuri

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: catheter-associated infection; CAUTI; urinary tract infection; healthcare-associated infection; active drain line clearance; burns; intra-abdominal pressure; measurement

Online: 30 September 2022 (04:13:24 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202403.1721.v1

Inflammation and Iron Profile in Children with Sickle Cell Disease in Cameroon: Frequency and Associated Factors

Romaric Tuono De Manfouo, Josué Simo Louokdom, Bernard Claude Chetcha, Prosper Cabral Biapa Nya, Claude Tayou Tagny, Constant Anatole Pieme

Subject: Biology And Life Sciences, Other Keywords: sickle cell anemia; iron profile; inflammation; associated factors

Online: 28 March 2024 (04:15:25 CET)

Show abstract| Download PDF| Share

Background and objectives: sickle cell disease is the most common hemoglobinopathy in the world. It is considered to be a real public health problem. Sickle cell patients are subjected to several factors causing inflammation such as iron metabolism. The study aimed to look for inflammation in children with sickle cell disease in Cameroon, identify the factors associated with inflammation, and raise the consequences for the patient including the iron profile and the profile of the hemogram. Materials and methods: We conducted an analytical cross-sectional study for 03 months. The sickle cell disease patients coming and/or followed at the Hematology Department of the Regional Hospital of Bafoussam and the Central Hospital of Yaoundé have been recruited. The exploration of inflammation was made by determining CRP, IL6, and ferritin concentrations. The hematological parameters and iron profile were evaluated using standard methods. Statistical analysis of the data was performed; Univariate and multivariate logistic regression analyses allowed to identification of factors associated with inflammation in patients, using the statistical tool R version 4.1.1.. The proportions were compared with the chi-square test when the expected numbers were greater than 5 and the Fisher test when not. Results: The frequency of inflammation in the population was 42.3%. Hyperferritinemia was significantly greater (p<0.001) in patients with inflammation compared to the non-inflammatory patients (96.8% and 76.7% respectively). Patients with inflammation showed a significant elevation of iron parameters (p<0.05). In addition, ferritin and IL6 elevation were associated with inflammation during sickle cell disease respectively (Or = 4.96; 95% CI [1.15-36.42]; p=0.056) and (Or =6.23; 95% CI [1.43-45.96]; p=0.030). Conclusions: The elevated iron in plasma is an effect of inflammation in sickle cell patients. Hence the need of controlling inflammation and iron in the latter is necessary.

Preprint ARTICLE | doi:10.20944/preprints202202.0082.v1

Discovery of Novel Trace Amine-Associated Receptor 5 (TAAR5) Antagonists Using a Deep Convolutional Neural Network

Carlotta Bon, Ting-Rong Chern, Elena Cichero, Terrence O'Brien, Stefano Gustincich, Raul R Gainetdinov, Stefano Espinoza

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Trace amine-associated receptor 5; antagonist; AtomNet; BRET.

Online: 7 February 2022 (11:57:16 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202103.0638.v1

Shugoshin: From a Perspective of Clinical Disorders

Ravinder Kumar, Meenakshi Agarwal

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Shugoshin; tumor suppressor; cancer; oncogene; tumour associated gene

Online: 25 March 2021 (15:31:59 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202401.1897.v1

Fixed-Time Aperiodic Intermittent Control for Quasi-bipartite Synchronization of Competitive Neural Networks

Shimiao Tang, Jiarong Li, Haijun Jiang, Jinling Wang

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Competitive neural network; Quasi-bipartite synchronization; Fixed-time intermittent control; External disturbance

Online: 26 January 2024 (09:01:04 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.0481.v1

Certain Results on Subclasses of Analytic and Bi-Univalent Functions Associated with Coefficients Estimates and Quasi-Subordination

Elaf Ibrahim Badiwi, Waggas Galib Atshan, Ameera N. Alkiffai, Alina Alb Lupas

Subject: Computer Science And Mathematics, Analysis Keywords: analytic functions, univalent function; fractional derivatives; convolution (qderivatives); quasi–subordination; coefficient estimate

Online: 7 November 2023 (16:21:13 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202308.1988.v1

Design and Optimization Strategies for Flexible Qua-si‑Solid‑State Thermo-Electrochemical Cells

Bingchen Huo, Fengxia Kuang, Cun-Yue Guo

Subject: Chemistry And Materials Science, Electronic, Optical And Magnetic Materials Keywords: thermo-electrochemical cells; redox couples; quasi‑solid‑state electrolyte; electrode; device integration

Online: 30 August 2023 (03:27:27 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.1688.v1

An Evaluation of Sun-Glint Correction Methods for UAV-Derived Secchi Depth Estimations in Inland Water Bodies

Edvinas Tiškus, Martynas Bučas, Diana Vaičiūtė, Jonas Gintauskas, Irma Babrauskienė

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: UAVs; Secchi depth; multispectral imagery; sun-glint; quasi-analytical algorithm; remote sensing

Online: 25 July 2023 (09:58:42 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202305.2071.v1

Application of Classification and Stage Evacuation in Station-city Integration Building: A Case Study of Chongqing East Station

Dan Ding, Wenbin Wei, Longlong Yang

Subject: Engineering, Architecture, Building And Construction Keywords: station-city integration; Chongqing East station; combined construction; Evacuation (quasi) safety zone

Online: 30 May 2023 (07:52:15 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202210.0367.v1

Rc Quasi-Distributed Sensor With Tree-Like Structure Adaptable for Physical Fields Measurement

Evgeny Denisov, Ilnaz Shafigullin

Subject: Engineering, Electrical And Electronic Engineering Keywords: quasi-distributed sensor; tree-like structure; sensitive RC elements; physical fields measurements

Online: 24 October 2022 (13:50:50 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202404.1713.v1

A Comprehensive Review of Fragile X Syndrome and Fragile X Premutation Associated Conditions in Africa

Chioma N.P. Mbachu, Ikechukwu Mbachu, Randi Hagerman

Subject: Clinical Medicine, Medicine And Pharmacology Keywords: Fragile X syndrome; Fragile X premutation associated conditions; Africa

Online: 26 April 2024 (08:15:57 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202401.1401.v1

NF-κB: Governing Innate Immunity in Cancer

Jessica Cornice, Daniela Verzella, Paola Arboretto, Davide Vecchiotti, Daria Capece, Francesca Zazzeroni, Guido Franzoso

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: NF-κB; Tumor-associated macrophages (TAMs); Tumor microenvironment (TME)

Online: 18 January 2024 (14:05:44 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.2013.v1

Modified Crosstalk between Phytohormones in Arabidopsis Mutants for PEP-Associated Proteins

Ivan A. Bychkov, Aleksandra A. Andreeva, Radomira Vankova, Jozef Lacek, Natalia V. Kudryakova, Victor V. Kusnetsov

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Arabidopsis thaliana; phytohormones; gene expression; PEP-associated proteins; mutants

Online: 26 December 2023 (14:09:46 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202310.0861.v1

Antineutrophil Cytoplasmic Antibody-associated Vasculitis and the Risk of Developing Incidental Tuberculosis: A Population-based Cohort Study

Shan-Ho Chan, Ming-Feng Li, Shih-Hsiang Ou, Mei-Chen Lin, Jen-Hung Wang, Po-Tsang Lee, Hsin-Yu Chen

Subject: Medicine And Pharmacology, Internal Medicine Keywords: antineutrophil cytoplasmic antibody-associated vasculitis; tuberculosis; population-based study

Online: 13 October 2023 (08:10:55 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202309.1932.v1

DNA damage response & senescence-associated secretory phenotype pathway: Emerging targets for anti-aging

Jawad Nadeem, Amna Parveen, Sun Yeou Kim

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Anti-aging, DNA damage response, senescence-associated secretory phenotype

Online: 28 September 2023 (04:56:53 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202309.1409.v1

Early and Late Complications after Cataract Surgery in Patients with Uveitis

Gentian Bajraktari, Tomislav Jukić, Miro Kalauz, Martin Oroz, Andrea Radolović Bertetić, Nenad Vukojević

Subject: Medicine And Pharmacology, Ophthalmology Keywords: uveitis-associated cataract; postoperative complications; phacoemulsification; uveitis; visual prognosis

Online: 21 September 2023 (04:56:43 CEST)

Show abstract| Download PDF| Share

Background and Objectives: Uveitis, a prevalent eye disorder characterized by inflammatory processes, often leads to cataract formation and significant visual impairment. This study aimed to evaluate preoperative conditions and postoperative outcomes following cataract surgery in uveitis patients. Materials and Methods: A retrospective study was conducted at the University Hospital Center Rebro Zagreb, Croatia, involving uveitis patients who underwent cataract surgery between 2013 and 2022. Eligible patients had uveitic cataracts affecting visual acuity or posterior segment visualization in a "quiet eye" and were disease-inactive for at least three months. Patients with certain preexisting ocular conditions were excluded. Data collected included patient demographics, uveitis type, preoperative therapy, preexisting lesions, and postoperative outcomes such as visual acuity, intraocular pressure, central macular thickness, and complications. Statistical analysis was performed to identify risk factors associated with complications. Results: The study included 105 patients. After cataract surgery, there was a significant improvement in visual acuity at various time points, with 90% of eyes showing improvement. Intraocular pressure decreased over time. Central macular thickness increased at three months post-surgery but remained stable thereafter. Early and late complications were observed in 52.4% and 63.8% of eyes, respectively. The most common complications were posterior capsular opacification, macular edema, and epiretinal membrane. Factors associated with complications varied between early and late stages but included age, age at onset of uveitis, and uveitis type. Conclusion: Cataract surgery in uveitis patients presents challenges but can lead to significant visual improvement. This study highlights the importance of careful patient selection, preoperative and postoperative inflammation management, and precise surgical techniques. Although complications were common, they were manageable, and most patients experienced improved vision, emphasizing the benefits of cataract surgery in this population. However, future investigations should address the study's limitations and further refine perioperative strategies.

Preprint ARTICLE | doi:10.20944/preprints202307.1717.v1

Indoor Air Contamination by Yeasts in Healthcare Facilities: Risks of Invasive Fungal Infection

Jean Phellipe Marques do Nascimento, Raniele dos Santos, Mirna Samile dos Santos Silva, Mykaella Andrade de Araújo, Lucas Anhezini, Daniela Évelin dos Santos, Eurípedes Alves da Silva-Filho

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Healthcare-associated infections; indoor air quality; infection control; Candida

Online: 25 July 2023 (11:50:29 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202306.1245.v1

Significance of Diabetic Kidney Disease Biomarkers in Predicting Metabolic-Associated Fatty Liver Disease

Jaehyun Bae, Byung-Wan Lee

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: diabetic kidney disease; metabolic-associated fatty liver disease; biomarker

Online: 16 June 2023 (13:36:04 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.0482.v1

A Ketogenic Diet in Combination With Gemcitabine Mitigates Pancreatic Cancer Associated Cachexia in Male and Female KPC Mice

Natalia E Cortez, Suraj Pathak, Cecilia Rodriguez Lanzi, Brian Hong, Rasheed O Sule, Ryman Crone, Fangyi Wang, Shuai Chen, Aldrin Gomes, Keith Baar, Gerardo Guillermo Mackenzie

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: cachexia; pancreatic cancer; ketogenic diet; gemcitabine; cancer-associated cachexia

Online: 7 June 2023 (03:53:16 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202305.1641.v1

Extensive Drug Resistance of Strong Biofilm-Producing Acinetobacter baumannii Strains Isolated from Infections and Colonization Hospitalized Patients in Southern Poland

Tomasz Kasperski, Dorota Romaniszyn, Estera Jachowicz-Matczak, Monika Pomorska-Wesołowska, Jadwiga Wójkowska-Mach, Agnieszka Chmielarczyk

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Acinetobacter baumannii; biofilm; extensively drug resistance; biofilm associated genes

Online: 23 May 2023 (10:33:26 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202301.0471.v1

Risk Factors of Cannula-associated Arterial Thrombosis following Extracorporeal Membrane Oxygenation support: A Retrospective Study

Ngan Hoang Kim Trieu, Xuan Thi Phan, Linh Thanh Tran, Huy Minh Pham, Dai Quang Huynh, Tuan Manh Nguyen, Anh Tuan Mai, Quan Quoc Minh Du, Bach Xuan Nguyen, Thao Thi Ngoc Pham

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: extracorporeal membrane oxygenation; cannula-associated arterial thrombosis; flow rate

Online: 26 January 2023 (08:33:01 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202208.0316.v1

Type of ANCA may be Superior to Clinical Phenotype in Distinguishing Different Clinical Entities in ANCA-associated Vasculitis

Afroditi Maria Konstantouli, Georgios Lioulios, Asimina Fylaktou, Maria Stangou

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: ANCA-associated vasculitis; Proteinase 3; Myeloperoxidase; Clinical Phenotype; Outcome

Online: 17 August 2022 (09:58:51 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201904.0209.v1

The Immunosuppressive Microenvironment of Classic Hodgkin Lymphoma and Therapeutic Approaches to Counter It

Donatella Aldinucci, Cinzia Borghese, Naike Casagrande

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Hodgkin lymphoma; tumor microenvironment; immune escape; tumor-associated macrophages

Online: 18 April 2019 (08:14:50 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201702.0098.v1

MicroRNAs in the Communication between Cancer Associated Fibroblasts (CAF) and Cancer Cells

Maren Schoepp, Anda Jana Stroese, Joerg Haier

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: MicroRNA; cancer associated fibroblasts; cell-cell communication; transformation; epigenetic

Online: 28 February 2017 (10:29:27 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.1583.v1

A Remark on Quasi-automorphisms and Deformable Structures in Quasi-set Theory and Its Account to the Logical Foundations of Quantum Theory

Décio Krause

Subject: Arts And Humanities, Philosophy Keywords: logical foundations of quantum theory; indistinguishability; indiscernibility; quantum objects; deformable structures; quasi automorphisms

Online: 21 June 2023 (16:52:36 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202109.0221.v1

Three-Dimensional Finite Element Investigation Into Effects of Implant Thread Design and Loading Rate on Stress Distribution in Dental Implants and Anisotropic Bone

Dawit Bogale Alemayehu, Yeau Ren Jeng

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: quasi-static load; abutment screw; dental implant; finite element method; dynamic load; mesiodistal

Online: 13 September 2021 (15:55:30 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202005.0463.v1

Comparative Genomics of Global SARS-CoV-2 Quasispecies Offers Insights into Its Microevolution and Holds Implications for Pathogenesis and Control

Santi M. Mandal, Suresh K. Mondol, Shriparna Mukherjee, Wriddhiman Ghosh, Ranadhir Chakraborty

Subject: Biology And Life Sciences, Virology Keywords: comparative genomics; SARS-CoV-2; microevolution; quasi-species; point mutation; disinfectants as mutagens

Online: 28 May 2020 (16:21:05 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202004.0114.v1

Asymptotic Dynamics of a Class of Third Order Rational Difference Equations

Sk Sarif Hassan, Soma Mondal, Swagata Mandal, Chumki Sau

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: rational difference equations; local asymptotic stability; periodic; Quasi-Periodic and Fractal-like trajectory

Online: 8 April 2020 (04:05:22 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202402.1100.v1

Improving Device-to-Device Reproducibility of Light-Emitting Diodes Based on Layered Halide Perovskites

Quang-Huy Do, Rémi Antony, Bernard Ratier, Johann Bouclé

Subject: Physical Sciences, Applied Physics Keywords: layered halide perovskites; perovskite light-emitting diodes (PeLED); quasi-2D; device-to-device reproducibility

Online: 20 February 2024 (06:32:32 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0088.v1

Moored Minds: An Experimental Insight into the Impact of Anchoring & Disposition Effect on Portfolio Performance

Riya Arora, Madhumathi R

Subject: Business, Economics And Management, Finance Keywords: disposition effect; anchoring bias; investment decisions; portfolio performance; stable markets; volatile markets; quasi-experiment

Online: 4 July 2023 (03:38:00 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202206.0413.v1

Application of Improved Quasi-Affine Transformation Evolutionary Algorithm in Power System Stabilizer Optimization

Jing Huang, Jiajing Liu, Cheng Zhang, Yu Kuang, Shaowei Weng

Subject: Engineering, Electrical And Electronic Engineering Keywords: Simulated annealing quasi-Affine Transformation Evolutionary (SA-QUATRE); Coordinated optimization design; Power system stabilizer

Online: 30 June 2022 (03:48:32 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202112.0097.v2

Accelerating Symmetric Rank-1 Quasi-Newton Method with Nesterov’s Gradient for Training Neural Networks

S. Indrapriyadarsini, Shahrzad Mahboubi, Hiroshi Ninomiya, Takeshi Kamio, Hideki Asai

Subject: Computer Science And Mathematics, Mathematics Keywords: Neural networks; quasi-Newton; symmetric rank-1; Nesterov’s accelerated gradient; limited memory; trust-region

Online: 8 December 2021 (17:51:54 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201701.0060.v1

Quasi-Interpolation Operators for Bivariate Quintic Spline Spaces and Their Applications

Rengui Yu, Chungang Zhu, Xianmin Hou, Li Yin

Subject: Computer Science And Mathematics, Mathematics Keywords: bivariate spline space; quasi-interpolation operator; type-2 triangulation 3; burgers’ equations; image reconstruction

Online: 12 January 2017 (10:04:06 CET)

Show abstract| Download PDF| Share

Preprint COMMUNICATION | doi:10.20944/preprints202401.0567.v1

Bromelain: Unveiling its Potential as a Natural Anti-Inflammatory Agent through Effective Binding to Apoptosis-associated Speck-like Containing CARD (ASC)

Ivan Vito Ferrari

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Apoptosis-associated speck-like containing; Bromelain; HDOCK SERVER

Online: 8 January 2024 (06:53:11 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.1967.v1

Oncogenic Human Papillomavirus Infection (HPV 16/18) and Associated Factors among Women in East Gojjam Zone, Northwest Ethiopia 2021

mamaru getinet

Subject: Medicine And Pharmacology, Anatomy And Physiology Keywords: OncoE6TM cervical test; HPV; East Gojjam zone; prevalence; associated factors

Online: 26 December 2023 (10:14:26 CET)

Show abstract| Download PDF| Share

Background: Human papillomavirus is a common pathogen that infects the skin and mucosal epithelium, is transmitted sexually; causes condylomas or squamous cell carcinomas. Two (16 and 18) of the 150 HPV serotypes are oncogenic types. Studies have been done on the infection by oncogenic human papillomavirus 16/18 and associated factors are found to be very limited in Ethiopia. Objective: This study aimed to assess the prevalence of oncogenic human papillomavirus infection (HPV 16/18) and associated factors among women. Methods: An institutional-based cross-sectional study was conducted among 337 women screened for cervical cancer in two hospitals in East Gojjam Zone from February to April 2021 G.C. Four BSc-qualified nurses who worked in the chosen hospitals collected the data using pretested questionnaire and an HPV test (OncoE6TM Cervical Test) specific to HPV16/18 in cervical swabs. Descriptive analysis was performed to determine the prevalence and a multivariate logistic regression model was used to identify the associated factors of HPV16/18 infection. Finally, statistical significance was declared at P < 0.05.Results: The prevalence of HPV infection was 14.2% (95% CI: 10.7% -18.1%). The mean age of the respondents was 36.7±9.1 years. Women with the age group of 55-65 years (AOR = 7.91, 95% CI: 1.95-32.09), early initiation of sexual intercourse (AOR = 5.36, 95% CI: 1.58-18.13), history of sexually transmitted infection (STI) (AOR = 3.52, 95% CI: 1.27-9.72), human immunodeficiency virus (HIV) positive status (AOR = 6.8, 95% CI: 1.99-23.54), and number of lifetime sexual partners (AOR = 4.37, 95% CI: 1.15-17.3) were important independent factors associated with the presence of oncogenic HPV infection. Conclusion and Recommendation: We found a relatively low prevalence of high-risk HPV infection. Age, early initiation of sexual intercourse at less than 18 years, STI of women, being HIV seropositive, and a number of sexual partners were important factors for high-risk HPV infection. Women aged > 46 years, women with early initiation of sex, a history of STI, being HIV positive, and a history of multiple sexual partners should be encouraged to be screened and vaccinated for HPV infection. Wider-ranging studies are also needed in HPV-infected women in association with the cervical lesion.

Preprint ARTICLE | doi:10.20944/preprints202311.1256.v1

TitleBiological Effects of “Inflammageing” on Human Oral Cells: Insights into a Potential Confounder of Age-Related Diseases

Elli Alexakou, Athina Bakopoulou, Danae A Apatzidou, Aristeidis Kritis, Andigoni Malousi, Vassiliki Anastassiadou

Subject: Biology And Life Sciences, Life Sciences Keywords: inflammageing; senescence; pro-inflammatory stimulus; Senescence Associated Secretory Phenotype (SASP)

Online: 20 November 2023 (16:15:05 CET)

Show abstract| Download PDF| Share

Objectives: The term "inflammageing” describes the process of inflammation-induced aging that leads living cells to a state of permanent cell cycle arrest due to chronic antigenic irritation. This in vitro study aimed to shed light on the mechanisms of “inflammageing” on human oral cells. Methods: Primary cultures of human gingival fibroblasts (hGFs) were exposed to variable pro-inflammatory stimuli, including lipopolysaccharide (LPS), Tumor Necrosis Factor-alpha (TNFa), and gingival crevicular fluid (GCF) collected from active periodontal pockets of systemically healthy patients. Inflammageing was studied through two experimental models, employing either late-passage (“aged”) cells (p.10) that were exposed to the pro-inflammatory stimuli or early-passage (“young”) cells (p.1) continuously exposed during a period of several passages (up to p.10) to the above-mentioned stimuli. Cells were evaluated for the expression of beta-galactosidase activity (histochemical staining), senescence-associated genes (qPCR analysis), and biomarkers related to a Senescence Associated Secretory Phenotype (SASP), through proteome profile analysis and bioinformatics. Results: A significant increase (p<0.05) of beta-galactosidase-positive cells was observed after exposure to each pro-inflammatory stimulus. The senescence-associated gene expression included upregulation for CCND1 and downregulation for SUSD6, and STAG1, a profile typical for cellular senescence. Overall, pro-inflammatory priming of late-passage cells caused more pronounced effects in terms of senescence, than long-term exposure of early-passage cells to these stimuli. Proteomic analysis showed induction of SASP, evidenced by upregulation of several pro-inflammatory proteins (IL-6, IL-10, IL-16, IP-10, MCP-1, MCP-2, M-CSF, MIP-1a, MIP-1b, TNFb, sTNF-RI, sTNF-RII, TIMP-2) implicated in cellular aging and immune responses. The least potent impact on the induction of SASP was provoked by LPS and the most pronounced by GCF. Conclusion: This study demonstrates that long-term exposure of hGFs to various pro-inflammatory signals induced or accelerated cellular senescence with the most pronounced impact noted for the late-passage cells. The outcome of this analyses provides insights into oral chronic inflammation, as a potential confounder of age-related diseases.

Preprint ARTICLE | doi:10.20944/preprints202304.0151.v1

The Surgical, Histopathological Characteristics, and Survival Outcome of Ovarian Clear Cell Carcinoma: A Retrospective Case Series Sharing the Experience of a Tertiary Cancer Centre over 10 Years

Sally EL Tawab, Sabina Nistor, Rene Roux, Sanjiv Manek, Kezia Geitskell, Ahmed Ahmed, Sean Kehoe, Hooman Soleymani majd

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Ovarian clear cell carcinoma; residual disease; recurrence; survival; endometriosis- associated

Online: 10 April 2023 (05:14:42 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202207.0078.v2

Mitochondrial Damage-Associated Molecular Patterns Content in Extracellular Vesicles Promotes Early Inflammation in Neurodegenerative Disorders

Claudia Deus, Henrique Tavares, Margarida Beatriz, Sandra Mota, Carla Lopes

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Extracellular vesicles; neurodegenerative disorders; mitochondrial damage-associated molecular patterns; inflammation

Online: 6 July 2022 (09:16:21 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202206.0096.v1

Hepatitis E Virus Seroprevalence and Associated Risk Factors in Pregnant Women Attending Antenatal Consultations in Senegal

Abou Abdallah Malick Diouara, Seynabou Lo, Cheikh Momar Nguer, Assane Senghor, Halimatou Diop Ndiaye, Noël Magloire Manga, Fodé Danfakha, Sidy Diallo, Marie Edouard Faye Dieme, Ousmane Thiam, Babacar Biaye, Ndèye Marie Pascaline Manga, Fatou Thiam, Habibou Sarr, Gora Lo, Momar Ndour, Sébastien Paterne Manga, Nouhou Diaby, Modou Dieng, Idy Diop, Yakhya Dieye, Coumba Toure Kane, Martine Peeters, Ahidjo Ayouba

Subject: Biology And Life Sciences, Virology Keywords: Hepatitis E; Associated risk factors; Pregnant women; Environment; Prevention; Senegal

Online: 7 June 2022 (08:06:52 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202201.0385.v1

Improved Cognitive Performances in Trace Amine-Associated Receptor 5 (TAAR5) Knock-out Mice

Silvia Maggi, Carlotta Bon, Stefano Gustincich, Valter Tucci, Raul R Gainetdinov, Stefano Espinoza

Subject: Social Sciences, Behavior Sciences Keywords: Trace amine-associated receptor 5; cognition; decision-making; switch task

Online: 25 January 2022 (14:49:51 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202101.0320.v2

Phylogenetic and Expression Analysis of CENH3 and APOLLO Genes in Sexual and Apomictic Boechera Species

Evgeny Bakin, Fatih Sezer, Aslıhan Özbilen, Irem Kilic, Buket Uner, Mike Rayko, Kemal Melih Taskin, Vladimir Brukhin

Subject: Biology And Life Sciences, Plant Sciences Keywords: Boechera; Brassicaceae; CENH3; APOLLO; apomixis associated genes; cell division; apomeiosis

Online: 20 December 2021 (10:40:57 CET)

Show abstract| Download PDF| Supplementary Files| Share

Apomictic plants (reproducing via asexual seeds), unlike sexual individuals, avoid meiosis and egg cell fertilization. Consequently, apomixis is very important for fixing maternal genotypes in the next plant generations. Despite the progress in the study of apomixis, molecular and genetic regulation of the latter remains poorly understood. So far APOLLO (Aspartate Glutamate Aspartate Aspartate histidine exonuclease) is one of the very few described genes associated with apomixis in Boechera species. The centromere-specific histone H3 variant encoded by CENH3 gene is essential for cell division. Mutations in CENH3 disrupt chromosome segregation during mitosis and meiosis since the attachment of spindle microtubules to a mutated form of the CENH3 histone fails. This paper presents in silico characteristic of APOLLO and CENH3 genes, which may affect apomixis. Also, we characterize the structure of CENH3, study expression levels of APOLLO and CENH3 in gynoecium/siliques of the natural diploid apomictic and sexual Boechera species at the stages of before and after fertilization. While CENH3 was a single copy gene in all Boechera species, the APOLLO gene have several polymorphic alleles associated with sexual and apomictic reproduction in the Boechera genera. Expression of the APOLLO apo-allele during meiosis was upregulated in gynoecium of apomict B. divaricarpa downregulating after meiosis until 4th day after pollination (DAP). On the 5th DAP, expression in apomictic siliques increased again. In sexual B. stricta gynoecium and siliques APOLLO apo-allele did not express. Expression of the APOLLO sex-allele during and after meiosis in gynoecium of sexual plants was several times higher than that in apomictic gynoecium. However, after pollination the sex-allele was downregulated in sexual siliques to the level of apomicts and increased sharply on the 5th DAP, while in apomictic siliques it almost did not express. At the meiotic stage, the expression level of CENH3 in the gynoecium of apomicts was two times lower than that of the sexual Boechera, decreasing in both species after meiosis and keep remaining very low in siliques of both species for several days after artificial pollination until the 4th DAP, when the expression level raised in sexual B. stricta siliques exceeding 5 times the level in apomictic B. divaricarpa siliques. We also discuss polymorphism and phylogeny of the APOLLO and CENH3 genes.

Preprint REVIEW | doi:10.20944/preprints202004.0331.v1

Coronavirus 2019 Infection in People with Associated Co-Morbidities: Case Fatality and ACE2 Inhibitors Treatment Concerns

Maryam Honardoost, Rokhsareh Aghili, Mohammad E. Khamseh

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: COVID-19; associated comorbidities; treatment; ACE2 inhibitors; Type 2 diabetes

Online: 19 April 2020 (05:42:22 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202202.0264.v1

Zonal Asymmetry of the Stratopause in the 2019/2020 Arctic Winter

Yu Shi, Oleksandr Evtushevsky, Gennadi Milinevsky, Andrew Klekociuk, Wei Han, Oksana Ivaniha, Yulia Andrienko, Valery Shulga, Chenning Zhang

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: stratopause; mesosphere; sudden stratospheric warming; polar vortex; zonal wind; quasi-biennial oscillation; planetary wave; stratosphere

Online: 22 February 2022 (04:07:39 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202108.0552.v1

The Hyperfunction Theory: An Emerging Paradigm for the Biology of Aging

David Gems

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: antagonistic pleiotropy; insulin/IGF-1 signalling; hyperfunction; quasi-programs; mTOR; theories of aging; programmatic aging

Online: 30 August 2021 (16:11:02 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201806.0095.v1

Sumudu Transform of Dixon Elliptic Functions With Non-Zero Modulus as Quasi C Fractions and Its Hankel Determinants

Adem Kilicman, Rathinavel Silambarasan

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: dixon elliptic functions; non-zero modulus; sumudu transform; hankel determinants; continued fractions; Quasi C fractions

Online: 6 June 2018 (13:05:28 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202312.0263.v1

Cancer‐Associated Fibroblast Heterogeneity in Oral Cancer

Julia Arebro, Che-Min Lee, Kevin L Bennewith, Cathie Garnis

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Cancer‐associated fibroblast, CAF subtype, oral squamous cell carcinoma, tumor microenvironment

Online: 5 December 2023 (11:11:14 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202310.1202.v1

The Risk of Death among Patients with Healthcare-Associated Infections and Cardiovascular Diseases Admitted in Intensive Care Unit in Romania

Mihaela Alexandra Budianu, Liviu Moraru, Bogdan Mihai Budianu, Judit Kovacs, Septimiu Voidăzan

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: healthcare-associated infections; Intensive Care Unit; cardiovascular diseases, multidrug resistant bacteria

Online: 18 October 2023 (18:26:38 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202310.1121.v1

Knowledge and Visual Differentiation Ability of the Pressure Injury Classification System and Incontinence-Associated Dermatitis among Hospital Nurses: A Descriptive Study

Seungmi Park, Eun Jung Kim, Son Ja Lee, Eun Jeong Kim, Ji Yeon Lee, Jung Eun Hong

Subject: Public Health And Healthcare, Nursing Keywords: clinical nurses; visual differentiation; diagnostic ability; pressure injury; incontinence-associated dermatitis

Online: 18 October 2023 (10:00:18 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202308.1794.v1

DNA Promoter Methylation of the ATM, APC, CDO1, RB1, TP53, WIF1 Genes in Patients with Head and Neck Squamous Cell Carcinoma

Segey Kurevlev, Anna Aghjanayan, Leyla Tskhovrebova, Konstantin Gordon, Andrey Polyakov, Mikhail Ratushnyy, Timur Fatkhudinov

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: DNA methylation; cancer associated genes; head and neck squamous cell carcinoma

Online: 25 August 2023 (08:33:03 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202306.0751.v1

Identification of EGF Receptor and Thrombospondin-1 As En-Dogenous Targets of ER-Associated Degradation Enhancer EDEM1 in HeLa Cells

Kohta Miura, Riko Katsuki, Shusei Yoshida, Ren Ohta, Taku Tamura

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Endoplasmic reticulum-associated degradation (ERAD); EDEM1; ER chaperone; EGF receptor; TSP1

Online: 12 June 2023 (03:58:21 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202207.0160.v2

NIH SenNet Consortium: Mapping Senescent Cells in the Human Body to Understand Health and Disease

Patty J Lee, Philip Blood, Katy Börner, Judith Campisi, Feng Chen, Heike Daldrup-Link, Phil De Jager, Li Ding, Francesca E. Duncan, Oliver Eickelberg, Rong Fan, Toren Finkel, Vesna Garovic, Nils Gehlenborg, Carolyn Glass, Ziv Bar-Joseph, Pragati Katiyar, So-Jin Kim, Melanie Königshoff, George Kuchel, Haesung Lee, Jun H. Lee, Jian Ma, Qin Ma, Simon Melov, Kay Metis, Ana L. Mora, Nicolas Musi, Nicola Neretti, João F. Passos, Irfan Rahman, Juan Carlos Rivera-Mulia, Paul Robson, Mauricio Rojas, Ananda L. Roy, Birgit Schilling, Pixu Shi, Jonathan Silverstein, Vidyani Suryadevera, Jichun Xie, Jinhua Wang, An-Kwok Ian Wong, Laura Niedernhofer

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Cellular Senescence Network; Normal Aging; Senescence; Senescence-associated secretory phenotype; SenNet

Online: 15 September 2022 (12:52:05 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202202.0232.v1

The microRNAs in the Antennae of Apolygus lucorum (Hemiptera: Miridae): Expression Properties and Targets Prediction

Adel Khashaveh, Xingkui An, Shuang Shan, Xiaoqian Pang, Yan Li, Xiaowei Fu, Yongjun Zhang

Subject: Biology And Life Sciences, Insect Science Keywords: Small RNA sequencing; miRNAs; Target prediction; Chemosensory-associated genes; Apolygus lucorum

Online: 18 February 2022 (10:01:58 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202009.0573.v1

Epidemiological and Microbiological Aspects of Health Care-associated Infections in Ukraine During the 2009–2019 Period

Yulian Konechnyi, Marta Panas, Iryna Tymchuk, Roksolana Konechna, Olena Borysiuk, Iryna Hubytska, Lesya Zhurakhivska, Olena Korniychuk

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: healthcare-associated infections; HCAIs; hospital acquired infections; nosocomial infections; statistical analysis

Online: 24 September 2020 (08:19:38 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201607.0003.v6

Farey Sequences and the Riemann Hypothesis

Darrell Cox

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Riemann hypothesis, Farey sequence, Gauss sum associated with a Dirichlet character

Online: 10 August 2016 (11:35:25 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.0517.v1

Equity Price Dynamics Under Shocks: In Distress or Short Squeeze

Cho-Hoi Hui, Chi-Fai Lo, Chi-Hei Liu

Subject: Business, Economics And Management, Finance Keywords: financial risk; market distress; predatory trading; short squeeze; constrained stochastic motion; quasi-bounded process; Covid-19

Online: 8 November 2023 (05:04:52 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202202.0177.v1

The Role of Quasi-Stationary Waves in Annual Cycle in Mid-Latitude Stratospheric and Mesospheric Ozone in 2011-2020

Chenning Zhang, Oleksandr Evtushevsky, Gennadi Milinevsky, Yulia Andrienko, Valerii Shulga, Wei Han, Yu Shi

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: quasi-stationary wave; stratosphere; mesosphere; westward phase tilt; geopotential height; ozone; annual and semi-annual oscillation

Online: 14 February 2022 (14:05:03 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201910.0213.v1

Quasi Cubic Trigonometric Curve and Surface

Guicang Zhang, Kai Wang

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: Quasi Extended Chebyshev space; optimal normalized totally positive basis; high-order continuity; shape preserving; shape features

Online: 18 October 2019 (11:33:13 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.2085.v1

Evaluation of the Antibacterial Activity of New Dermaseptin Derivatives against Acinetobacter baumannii

Houda HADDAD, Radhia MEJRI, Alyne Rodriguez De ARAUJO, Amira Zaïri

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Dermaseptin B2; Dermaseptin S4; analogs; Acinetobacter baumannii; Healthcare-Associated Infections; Antibacterial activity

Online: 27 December 2023 (10:24:49 CET)

Show abstract| Download PDF| Share

Search Results

255 articles found