Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Risk of Death among Patients with Healthcare-Associated Infections and Cardiovascular Diseases Admitted in Intensive Care Unit in Romania

Version 1 : Received: 17 October 2023 / Approved: 17 October 2023 / Online: 18 October 2023 (18:26:38 CEST)

A peer-reviewed article of this Preprint also exists.

Budianu, M.-A.; Moraru, L.; Roiban, A.L.; Budianu, B.-M.; Kovacs, J.; Mitranovici, M.-I.; Voidăzan, S. The Risk of Death among Patients with Healthcare-Associated Infections and Cardiovascular Diseases Admitted to the Intensive Care Unit in Romania. Journal of Cardiovascular Emergencies 2024, 0, doi:10.2478/jce-2024-0001. Budianu, M.-A.; Moraru, L.; Roiban, A.L.; Budianu, B.-M.; Kovacs, J.; Mitranovici, M.-I.; Voidăzan, S. The Risk of Death among Patients with Healthcare-Associated Infections and Cardiovascular Diseases Admitted to the Intensive Care Unit in Romania. Journal of Cardiovascular Emergencies 2024, 0, doi:10.2478/jce-2024-0001.

Abstract

Nowadays, healthcare-associated infections (HAIs) represent a major global public health problem and the burden of these infections is high. In order to reduce the incidence of HAIs and to prevent the spread antibi-otics resistant organisms is mandatory to develop surveillance systems. We undertook a retrospective case-control study of all patients presenting HAIs admitted in Intensive Care Unit (ICU) in order to assess risk factors associated with death among patients with HAIs. Patients admitted to Intensive Care Unit who died were more likely to present an infection with a multidrug resistant bacteria, an infection with Acineto-bacter baumannii, and to suffer from acute myocardial infarction. Among the patients enrolled in the study, a higher probability of death was also observed in association with certain gram-negative pathogens: Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa. The longer the patient remains admitted in ICU, the higher the risk of getting an infection that can often become fatal. Acquiring a noso-comial infection also increases the length of hospitalization which will lead to increased financial damage.

Keywords

healthcare-associated infections; Intensive Care Unit; cardiovascular diseases, multidrug resistant bacteria

Subject

Public Health and Healthcare, Public Health and Health Services

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