The Multidisciplinary Preprint Platform

Pre-Graduate and Post-Graduate Medical Education in the Health Sciences
Prof. Dr. Joaquín María García-Estañ López
Ecofriendly Materials
Dr. Manoj Gupta
Teaching Sociology
Prof. Dr. Sandro Nuno Ferreira de Serpa
Food Analytical Methods
Prof. Dr. Gavino Sanna
Quantum Computing
Prof. Dr. Lester Ingber


2-Deoxy-d-glucose Inhibits Replication of Novel Coronavirus (SARS-CoV-2) with Adverse Effects on Host Cell Metabolism
The treatment of viral infections is challenging owing to the intricate structure and metabolism of the viruses. In addition, they can highjack host cellular metabolism, mutate and adapt to harsh ...
Paradigm Shift: an Overview on Nutrigenetics and Nutrigenomics
Nutrigenetics concerns individual differences in the reaction to food based on the genetic factors. Nutrigenomics analyses direct influences of nutrients on gene expression. Both terms are explained in our review ...
Bacterial Nomenclature in the Era of Genomics
The remarkable success of taxonomic discovery, powered by culturomics, genomics and metagenomics, creates a pressing need for new bacterial names, while holding a mirror up to the slow pace of ...
Topology Optimization of Large-Scale 3D Morphing Wingstructures
This work proposes a systematic topology optimization approach to simultaneously design the morphing functionality and actuation in three-dimensional wing structures. The actuation is assumed to be a linear strain-based expansion ...
High-Resolution Imaging of Bacterial Spatial Organization with Vertical Cell Imaging by Nanostructured Immobilisation (VerCINI)
Light microscopy is indispensable for analysis of bacterial spatial organization. However, imaging in bacteria is difficult due to their small sizes and the fact that most species are non-spherical, meaning ...


Walking Around Ribosomal Small Subunit: A Possible “Tourist Map” for an Electron Hole
Despite several decades of research, the physics underlying translation – protein synthesis at the ribosome – remains poorly studied. For instance, the mechanism coordinating various events occurring in distant parts ...
Receptor Tyrosine Kinases as Candidate Prognostic Biomarkers in Meningioma
Meningioma (MGM) is the most common type of intracranial tumor in adults. The validation of novel prognostic biomarkers to better inform tumor stratification and clinical prognosis is urgently needed. Many ...
A Hierarchical Generative Embedding Model for Influence Maximization in Attributed Social Networks
Nowadays, we use social networks such as Twitter, Facebook, WeChat and Weibo as means to communicate with each other and get to know others. Gradually social networks has become indispensable ...
Thyroid Hormone Receptor Beta as Tumor Suppressor: Untapped Potential in Treatment and Diagnostics in Solid Tumors
There is compelling evidence that the nuclear receptor TRβ, a member of the thyroid hormone receptor (TR) family, is a tumor suppressor in thyroid, breast and other solid tumors. Cell-based ...
Transfer Learning for the Detection and Diagnosis of Types of Pneumonia Including Pneumonia Induced by the COVID-19 from Chest X-Ray Images
Accurate early diagnosis of COVID-19 viral pneumonia, primarily in asymptomatic people is essential to reduce the spread of the disease, the burden on healthcare capacity, and the overall death rate. ...
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Inclusion of COVID19 Preprints in the iSearch COVID-19 Portfolio

New Feature—Research Topics

Preservation Agreement Between Portico and Preprints

Our Policy on Submissions Related to COVID-19


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Authors upload their manuscript and supplementary files via the online submission system.
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Preprints editors carry out initial checks on content, decisions are made within 24 hours.
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