Vergov, B.; Angelova, A.; Baldzhieva, A.; Kalchev, Y.; Tsochev, G.; Murdjeva, M. Gordonia sputi as an Arising Causative Agent of Bacteremia in Immunocompromised Comorbid Dialysis Patients—A Case Report. Healthcare2023, 11, 2059.
Vergov, B.; Angelova, A.; Baldzhieva, A.; Kalchev, Y.; Tsochev, G.; Murdjeva, M. Gordonia sputi as an Arising Causative Agent of Bacteremia in Immunocompromised Comorbid Dialysis Patients—A Case Report. Healthcare 2023, 11, 2059.
Vergov, B.; Angelova, A.; Baldzhieva, A.; Kalchev, Y.; Tsochev, G.; Murdjeva, M. Gordonia sputi as an Arising Causative Agent of Bacteremia in Immunocompromised Comorbid Dialysis Patients—A Case Report. Healthcare2023, 11, 2059.
Vergov, B.; Angelova, A.; Baldzhieva, A.; Kalchev, Y.; Tsochev, G.; Murdjeva, M. Gordonia sputi as an Arising Causative Agent of Bacteremia in Immunocompromised Comorbid Dialysis Patients—A Case Report. Healthcare 2023, 11, 2059.
Abstract
Improvement in medical care has turned severe diseases into chronic conditions, but often their treatment and use of medical devices are related to specific complications. Here we present a clinical case of a long-term dialysis patient, who is infected with a rare opportunistic infectious agent – Gordonia sputi. In recent years the incidence of Gordonia spp. infections in immunocompromised patients with central venous catheters (CVC) appear to rise. Their isolation and identification are challenging and require modern techniques. In addition, the treatment is usually persistent and often results in CVC extraction, which is associated with further risk and costs for the patient. We also studied the alternations in the immune status of the patient caused by long-term renal replacement therapy and persistent HCV infection. Antibiotic therapy and immunostimulation with Inosine pranobex lead to successful eradication of the infection without the need for CVC replacement.
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