Version 1
: Received: 24 November 2023 / Approved: 24 November 2023 / Online: 27 November 2023 (10:22:14 CET)
How to cite:
Hsia, C.; Su, H.; Chen, Y.; Chuang, H.; Chien, Y. Effects of Probiotics in Elderly Hospitalized Tube-Fed Patients with Antibiotic Use. Preprints2023, 2023111669. https://doi.org/10.20944/preprints202311.1669.v1
Hsia, C.; Su, H.; Chen, Y.; Chuang, H.; Chien, Y. Effects of Probiotics in Elderly Hospitalized Tube-Fed Patients with Antibiotic Use. Preprints 2023, 2023111669. https://doi.org/10.20944/preprints202311.1669.v1
Hsia, C.; Su, H.; Chen, Y.; Chuang, H.; Chien, Y. Effects of Probiotics in Elderly Hospitalized Tube-Fed Patients with Antibiotic Use. Preprints2023, 2023111669. https://doi.org/10.20944/preprints202311.1669.v1
APA Style
Hsia, C., Su, H., Chen, Y., Chuang, H., & Chien, Y. (2023). Effects of Probiotics in Elderly Hospitalized Tube-Fed Patients with Antibiotic Use. Preprints. https://doi.org/10.20944/preprints202311.1669.v1
Chicago/Turabian Style
Hsia, C., Han-Chuan Chuang and Yi-wen Chien. 2023 "Effects of Probiotics in Elderly Hospitalized Tube-Fed Patients with Antibiotic Use" Preprints. https://doi.org/10.20944/preprints202311.1669.v1
Abstract
This study aimed to investigate the efficacy of probiotics in elderly hospitalized tube-fed patients undergoing antibiotic therapy for Clostridium difficile-associated diarrhea (CDAD). Probiotics were administered to 29 patients, with twice-daily doses for 7 days following the completion of antibiotic treatment. In the probiotic group, while stool form showed no significant change, there was a significant decrease in stool frequency. Conversely, the control group exhibited improved stool form but not frequency. The probiotic group maintained a significant difference in stool form during the follow-up period. Additionally, the control group showed a positive correlation between stool form, frequency, antibiotic therapy, and intensive care unit admission, which was not observed in the probiotic group. These findings suggest that supplementing with probiotics can effectively normalize stool form in elderly hospitalized tube-fed patients undergoing antibiotic treatment for CDAD, highlighting the potential benefits of probiotic intervention in this specific population.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
