Bromelain: Unveiling its Potential as a Natural Anti-Inflammatory Agent through Effective Binding to Apoptosis-associated Speck-like Containing CARD (ASC)

Ivan Vito Ferrari

doi:10.20944/preprints202401.0567.v1

Preprint Communication Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 7 January 2024 / Approved: 8 January 2024 / Online: 8 January 2024 (06:53:11 CET)

This theoretical study presents a novel perspective on the potential anti-inflammatory properties of Bromelain, a natural agent extracted from pineapple stems. The investigation explores the binding capabilities of Bromelain to Apoptosis-associated speck-like containing CARD (ASC), a crucial adapter molecule known for its involvement in inflammatory processes and inflammasome formation. For the first time, these findings suggest that Bromelain exhibits a notable affinity for ASC, indicating its promising role as a natural anti-inflammatory agent. This study sheds light on the molecular interactions that may contribute to Bromelain's therapeutic potential in modulating inflammatory responses.

Apoptosis-associated speck-like containing; Bromelain; HDOCK SERVER

Biology and Life Sciences, Immunology and Microbiology

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Bromelain: Unveiling its Potential as a Natural Anti-Inflammatory Agent through Effective Binding to Apoptosis-associated Speck-like Containing CARD (ASC)

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