REVIEW
|
doi:10.20944/preprints202207.0160.v2
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Cellular Senescence Network; Normal Aging; Senescence; Senescence-associated secretory phenotype; SenNet
Online: 15 September 2022 (12:52:05 CEST)
ARTICLE
|
doi:10.20944/preprints202311.1256.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
inflammageing; senescence; pro-inflammatory stimulus; Senescence Associated Secretory Phenotype (SASP)
Online: 20 November 2023 (16:15:05 CET)
REVIEW
|
doi:10.20944/preprints202301.0302.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
ferroptosis; senescence; ageing; disease
Online: 17 January 2023 (09:07:35 CET)
REVIEW
|
doi:10.20944/preprints202404.0659.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
aging; senescence; toxicology; gerontogen; senotherapy
Online: 10 April 2024 (03:17:10 CEST)
REVIEW
|
doi:10.20944/preprints202108.0448.v2
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
stroke; cellular senescence; coagulation; adhesion
Online: 14 October 2021 (15:21:58 CEST)
REVIEW
|
doi:10.20944/preprints202105.0427.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Cellular senescence; Lung fibrosis; Pathogenesis
Online: 19 May 2021 (07:35:10 CEST)
REVIEW
|
doi:10.20944/preprints202105.0409.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Macrophages; Senescence; Immunosenescence; Immunometabolism; Aging
Online: 18 May 2021 (10:15:20 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0354.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
MWCNT; senescence; pulmonary fibrosis; epithelial
Online: 14 May 2021 (17:05:25 CEST)
REVIEW
|
doi:10.20944/preprints202102.0362.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
polyamines; arginase; senescence; aging; neurodegeneration
Online: 17 February 2021 (10:05:38 CET)
ARTICLE
|
doi:10.20944/preprints202007.0672.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
aging; telomeres; senescence; mortality; disease
Online: 28 July 2020 (10:07:22 CEST)
REVIEW
|
doi:10.20944/preprints201811.0382.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
senescence; demethylases; epigenetics; histones; cancer
Online: 16 November 2018 (07:21:53 CET)
REVIEW
|
doi:10.20944/preprints202405.2008.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
immune checkpoint inhibitor; aging; cellular senescence; immune-related adverse events
Online: 10 June 2024 (04:21:20 CEST)
REVIEW
|
doi:10.20944/preprints202211.0564.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
cellular senescence; metastasis; metabolic adaptation; invasion
Online: 30 November 2022 (04:23:43 CET)
SHORT NOTE
|
doi:10.20944/preprints202009.0401.v2
Subject:
Biology And Life Sciences,
Ecology, Evolution, Behavior And Systematics
Keywords:
life history; longevity; senescence; stochastic environments
Online: 26 July 2022 (08:51:22 CEST)
REVIEW
|
doi:10.20944/preprints202105.0310.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
aging; geroscience; hallmarks; paradigm; senescence; theory
Online: 13 May 2021 (14:29:48 CEST)
REVIEW
|
doi:10.20944/preprints202102.0127.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Osteoporosis; Senescence; SASP; Aging; Radiation; Senotherapeutic
Online: 3 February 2021 (17:00:00 CET)
REVIEW
|
doi:10.20944/preprints202407.0190.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
adipose-derived stem cells; mesenchymal stem cells; ageing; senescence; stem cell therapy; senescence; diabetes; senolytic drugs
Online: 2 July 2024 (10:24:03 CEST)
ARTICLE
|
doi:10.20944/preprints202212.0442.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
P21; CDKN1A; glioblastoma; senescence; cancer senescence; gene overexpression; gene knock-in; CRISPR/Cas9; dCas; dCas-VPR
Online: 23 December 2022 (04:10:22 CET)
REVIEW
|
doi:10.20944/preprints202410.0607.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
Senescence; Sirtuins; Endocrine; Hormone; Bioavailability; Drug delivery
Online: 8 October 2024 (17:03:35 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202407.2497.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
ESRD; dialysis; hemodiafiltration; Immune senescence; immune exhaustion
Online: 31 July 2024 (09:02:45 CEST)
ARTICLE
|
doi:10.20944/preprints202312.0304.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
blood derived products; cellular senescence; fibroblast; skin
Online: 6 December 2023 (04:03:43 CET)
ARTICLE
|
doi:10.20944/preprints202312.0048.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
senescence; cell; chronic kidney disease; kidney tubules
Online: 1 December 2023 (05:32:39 CET)
REVIEW
|
doi:10.20944/preprints202311.0006.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
MSCs; tumor transformation; hematological cancers; senescence; inflammation
Online: 1 November 2023 (04:05:53 CET)
ARTICLE
|
doi:10.20944/preprints202310.1432.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
Lipogenesis; depigmenting activity; aging; senescence; wound healing
Online: 23 October 2023 (15:25:57 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1960.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Water use efficiency; Gene expression; Senescence; Drought
Online: 29 August 2023 (13:35:02 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1756.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
endometrial stromal cells; senescence; oncogenes; cancer; HRASG12V
Online: 26 July 2023 (10:39:31 CEST)
REVIEW
|
doi:10.20944/preprints202307.1278.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
evolution, evolvability, biology, gerontology, lifespan, senescence, genetics
Online: 19 July 2023 (04:18:37 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202206.0145.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
ovary; PRP; senescence; rejuvenation; hypoxia; telomere length
Online: 9 June 2022 (11:16:03 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202204.0124.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Senescence; EMT; NF-κB; Inflammation; Epigenetics; Aging
Online: 13 April 2022 (10:22:37 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0637.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
glioblastoma; neural stem cells; replicative senescence; metastasis
Online: 28 August 2020 (11:33:23 CEST)
REVIEW
|
doi:10.20944/preprints202004.0532.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
cellular senescence; SARS-CoV-2; coronavirus; aging
Online: 30 April 2020 (13:58:41 CEST)
REVIEW
|
doi:10.20944/preprints202406.0057.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
senescence; SASP (senescence‐associated secretory phenotype); immune surveillance; immunosuppression; senolytics; tumor microenvironment; cancer therapy; therapy resistance
Online: 3 June 2024 (09:54:54 CEST)
REVIEW
|
doi:10.20944/preprints202409.1049.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
dynapenia; muscle fiber atrophy; motor unit; ageing; senescence
Online: 13 September 2024 (08:25:06 CEST)
REVIEW
|
doi:10.20944/preprints202408.0653.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
stem cells; epigenetics; methylation; acetylation; histone; cellular senescence
Online: 12 August 2024 (03:20:22 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1775.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
iPSC-derived fibroblast; transformation; senescence; SASP; DNA repair
Online: 26 April 2024 (20:00:58 CEST)
REVIEW
|
doi:10.20944/preprints202401.0975.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
mitochondrial dysfunction; senescence; cardiac; cardiomyocyte; cardiac ischemia reperfusion
Online: 12 January 2024 (04:06:44 CET)
ARTICLE
|
doi:10.20944/preprints202312.1454.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
cell senescence; hepatocellular carcinoma; G6PD; molecular subtypes; immunotherapy
Online: 19 December 2023 (12:05:10 CET)
ARTICLE
|
doi:10.20944/preprints202310.1001.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
EHF; NDRG2; STAT3; Senescence; Breast cancer; TCGA data
Online: 17 October 2023 (05:09:29 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0091.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
calorie restriction; aging; inflammation; autophagy; senescence.; skeletal muscle
Online: 6 September 2022 (11:01:40 CEST)
REVIEW
|
doi:10.20944/preprints202105.0372.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Aging; Microbiome; Probiotics; Cellular senescence; SASP; Stress; Immunity
Online: 17 May 2021 (08:51:53 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202101.0514.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Senescence; Immortalization; Epithelial to Mesenchymal Transition; Carcinogenesis; Hypothesis
Online: 25 January 2021 (15:31:18 CET)
ARTICLE
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
obesity; mesenchymal stromal cells; cell cycle; senescence; differentiation
Online: 27 January 2020 (09:18:05 CET)
ARTICLE
|
doi:10.20944/preprints201908.0189.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
rice; leaf senescence; abscisic acid (ABA); OsWRKY; NAC
Online: 18 August 2019 (03:19:48 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1380.v2
Subject:
Biology And Life Sciences,
Aging
Keywords:
inflammasome; NLRP3; cellular senescence; antiinflammatory macrolides; alveolar macrophages; COPD
Online: 25 March 2024 (08:49:57 CET)
REVIEW
|
doi:10.20944/preprints202309.1932.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Anti-aging, DNA damage response, senescence-associated secretory phenotype
Online: 28 September 2023 (04:56:53 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0001.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
ovarian cancer; ALDH1A1; cancer stem cells; senescence; chemotherapy resistance
Online: 2 May 2022 (09:39:22 CEST)
ARTICLE
|
doi:10.20944/preprints202201.0304.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Sca-1+CD31− cells; Nr1d1; cell senescence; Serpina3; Nr4a3
Online: 20 January 2022 (11:24:08 CET)
REVIEW
|
doi:10.20944/preprints202110.0046.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
ageing; inflammation, cytokines, inflammageing; inflammageing; immunosenescence; immunosurveillance; senescence; SASP
Online: 4 October 2021 (11:00:22 CEST)
REVIEW
|
doi:10.20944/preprints202107.0090.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Senescence; EMT; Inflammation; GRN; Attractors; Carcinomas; Cellular plasticity; Convergence
Online: 5 July 2021 (10:39:20 CEST)
REVIEW
|
doi:10.20944/preprints202005.0388.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
GDNF; SOX1; CAFs; senescence; aging cell; methylation; tumour; glioma
Online: 24 May 2020 (16:53:56 CEST)
REVIEW
|
doi:10.20944/preprints202001.0087.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Chronic stress; Vascular senescence; inflamamtion; atherosclerosis; dipeptidyl peptidase-4
Online: 9 January 2020 (13:05:26 CET)
REVIEW
|
doi:10.20944/preprints201905.0101.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Transgenic; Cancer; Carcinogenesis; Immortality; Autonomy; cancer stem cells; senescence
Online: 9 May 2019 (11:29:34 CEST)
ARTICLE
|
doi:10.20944/preprints202408.1917.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
placental extracts; aging; human mesenchymal stem-cell-derived exosomes; senescence
Online: 27 August 2024 (11:54:11 CEST)
ARTICLE
|
doi:10.20944/preprints202408.0594.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
Senescence; chronic kidney disease; acute kidney injury; biomarker; machine learning
Online: 8 August 2024 (08:48:50 CEST)
ARTICLE
|
doi:10.20944/preprints202311.1671.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
antioxidant; dyslipidemia; kidney; liver; ovary; radio imaging; senescence; testis; zebrafish
Online: 27 November 2023 (11:20:02 CET)
ARTICLE
|
doi:10.20944/preprints202307.1589.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
aging; biomarkers; lncRNA; NEAT1; PURPL; RRAD; senescence; smooth muscle cells
Online: 24 July 2023 (10:02:09 CEST)
ARTICLE
|
doi:10.20944/preprints202112.0330.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
biostimulant; carotenoids; chlorophyll; IBA; leaf senescence; NAA; phenology; soluble proteins
Online: 21 December 2021 (12:40:44 CET)
ARTICLE
|
doi:10.20944/preprints202410.2229.v1
Subject:
Neuroscience And Neurology,
Medicine And Pharmacology
Keywords:
senescence-associated secretory phenotype; craniopharyngioma; oil machinery fluid; immunohistochemistry; electron microscopy.
Online: 29 October 2024 (09:44:38 CET)
ARTICLE
|
doi:10.20944/preprints202404.0967.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
Gestational Diabetes Mellitus; immune infiltration; senescence; WGCNA, machine learning; CECR1; TACC2
Online: 15 April 2024 (13:23:16 CEST)
ARTICLE
|
doi:10.20944/preprints202401.2003.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Senescence; structure-function screen; synthetic hormone; sex differences; sex-specific; senomorphic
Online: 29 January 2024 (12:49:45 CET)
ARTICLE
|
doi:10.20944/preprints202401.1760.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Pulsed Electromagnetic Fields (PEMFs); cancer therapeutics; cell viability; cell death; senescence
Online: 25 January 2024 (01:58:33 CET)
ARTICLE
|
doi:10.20944/preprints202401.1511.v1
Subject:
Biology And Life Sciences,
Forestry
Keywords:
Alpha-grass; Water exchange; Pine competence; Semi-arid woodlands; Leaf senescence
Online: 19 January 2024 (14:04:11 CET)
REVIEW
|
doi:10.20944/preprints202311.1711.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cell proliferation; cell fate; ERK; senescence; cell signaling; EMT; apoptosis; pluripotency
Online: 28 November 2023 (08:10:31 CET)
ARTICLE
|
doi:10.20944/preprints202410.0716.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
partial reprogramming; mesenchymal stem cells; replicative senescence; rejuvenation; Sendai virus; Yamanaka factors
Online: 9 October 2024 (15:31:48 CEST)
ARTICLE
|
doi:10.20944/preprints202408.1619.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Epigenetic Reprogramming; Aging; Regenerative Medicine; DNA Methylation; Cellular Rejuvenation; CRISPR-Cas9; Senescence
Online: 22 August 2024 (06:02:18 CEST)
REVIEW
|
doi:10.20944/preprints202408.0650.v2
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
cancer biology; etiology; endopolyploidy; transformation; senescence; carcinogen; cell cycle regulation; unifying theory
Online: 19 August 2024 (13:20:20 CEST)
ARTICLE
|
doi:10.20944/preprints202402.1509.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Insulin-like growth factor binding proteins; liver fibrosis; cellular senescence; steatohepatitis; steatosis.
Online: 27 February 2024 (10:06:34 CET)
ARTICLE
|
doi:10.20944/preprints202306.1922.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Fisetin; cell senescence; sheep; cerebral brain cortex; cerebellum; hippocampus; neurons; astrocytes; microglia
Online: 27 June 2023 (13:59:18 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1946.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
RACK1B; Rice; Salt stress; Stay-green; Light Harvesting Complex; Chlorophyll degradation; Senescence
Online: 29 May 2023 (02:26:49 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0033.v1
Subject:
Biology And Life Sciences,
Forestry
Keywords:
Fagus sylvatica; Quercus petraea; flushing; leaf senescence; nutrition; phosphorus effect; phenology shift
Online: 4 April 2023 (02:36:38 CEST)
REVIEW
|
doi:10.20944/preprints202207.0423.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Aging; cellular senescence; fibroblast; osteoarthritis; remodeling-associated secretory phenotype (RASP); remodeling activation
Online: 27 July 2022 (13:38:36 CEST)
ARTICLE
|
doi:10.20944/preprints201805.0389.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
cyanidin 3-O-glucoside; flower senescence; isosalipurposide; Oenothera; petal color change; quercitrin
Online: 28 May 2018 (08:49:47 CEST)
ARTICLE
|
doi:10.20944/preprints202410.0728.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Wheat; flag leaf senescence; drought; antioxidant enzymes; expression of SOD genes; ultrastructural changes
Online: 10 October 2024 (10:05:43 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0235.v2
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
aging; captive breeding; Dasyuridae; lymphoma; marsupial; senescence; reproductive pathology; Sminthopsis douglasi; Australian wildlife
Online: 22 February 2024 (12:33:40 CET)
ARTICLE
|
doi:10.20944/preprints202401.0602.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
conofolidine; bisindole alkaloids; carcinoma cell lines; cytotoxicity; apoptosis; senescence; ROS generation; γ -H2AX
Online: 8 January 2024 (09:17:51 CET)
ARTICLE
|
doi:10.20944/preprints202211.0410.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Leukemia; imidazo[1,2-a]pyridines; selenide; oxidative stress; senescence; chronic myeloid leu-kemia.
Online: 22 November 2022 (07:49:44 CET)
BRIEF REPORT
|
doi:10.20944/preprints202207.0144.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Protein Kinase C; PKCeta; autophagy; senescence; chemoresistance; oxidative stress; ER stress; 3MA; chloroquine
Online: 10 July 2022 (06:42:23 CEST)
REVIEW
|
doi:10.20944/preprints202308.1688.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer; senescence; asymmetric and symmetric division; loss of function; DNA-damage repair; reprogramming; malignancy
Online: 26 December 2023 (09:54:12 CET)
REVIEW
|
doi:10.20944/preprints202310.1924.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
calcium signaling, caveolae; caveolin-1; cell senescence; ECs, eNOS, endocytosis; lipid rafts; signal transduction.
Online: 30 October 2023 (11:13:10 CET)
REVIEW
|
doi:10.20944/preprints202204.0011.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
adipose tissue; adipose precursor cells; obesity; senescence; oxidative stress; type 2 diabetes; cardiovascular disease
Online: 4 April 2022 (07:34:50 CEST)
ARTICLE
|
doi:10.20944/preprints202112.0325.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
phenotyping; proximal sensing; reflectance imaging; vegetation indices; hyperspectral reflectance; chlorophylls; carotenoids; anthocyanins; senescence; ripening
Online: 21 December 2021 (12:23:13 CET)
HYPOTHESIS
|
doi:10.20944/preprints202004.0143.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
SARS-CoV-2; COVID-19; IL-6; inflamm-aging; immune senescence; host-directed therapies
Online: 9 April 2020 (08:38:22 CEST)
REVIEW
|
doi:10.20944/preprints202410.0983.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer’s disease; Tauopathy; Tau; Ubiquitin-proteasome system; Autophagy; Aggrephagy; Nucleophagy; Proteotoxic stress; Cellular senescence; Senolytic drugs
Online: 14 October 2024 (11:26:14 CEST)
ARTICLE
|
doi:10.20944/preprints202310.0573.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
microscopy; optical diffraction tomography; Raman spectroscopy; therapy-induced senescence; cell engulfing; vacuole; cancer; cell-in-cell
Online: 10 October 2023 (05:32:15 CEST)
REVIEW
|
doi:10.20944/preprints202109.0189.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
circadian clock; epigenetic clock; aging; senescence; reprogramming; methylome; DNA methylation; CpG-islands; induced pluripotent stem cells
Online: 10 September 2021 (15:13:04 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0244.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Stress; epigenetics; senescence; cognition; age-related cognitive decline; Alzheimer’s disease; SAMP8; SAMR1; oxidative stress; inflammation; autophagy
Online: 21 January 2020 (11:44:35 CET)
REVIEW
|
doi:10.20944/preprints201806.0056.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
mTOR; mTORC1; mTORC2; rapamycin; rapalogues; rapalogs; mTOR inhibitors; senescence; ageing; aging; cancer; neurodegeneration; immunosenescence; senolytics; biomarkers
Online: 5 June 2018 (09:49:19 CEST)
REVIEW
|
doi:10.20944/preprints202409.1125.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
insulin resistance; hyperinsulinemia; type 2 diabetes; treatments; adverse effects; risk factor; cardiovascular disease; cellular senescence; cancer; neurodegenerative disease
Online: 14 September 2024 (10:27:36 CEST)
REVIEW
|
doi:10.20944/preprints202311.1772.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
prediabetes; senescence; blood-based biomarkers; aging; age-related diseases; inflammation; oxidative stress; vascular dynamics; metabolic disorders; chronic inflammation
Online: 29 November 2023 (04:48:13 CET)
REVIEW
|
doi:10.20944/preprints202309.1166.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
ethylene biosynthesis and regulation; cell division and elongation; flower and fruit development; chloroplast development; photosynthesis; senescence and abscission
Online: 19 September 2023 (03:29:08 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0635.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Free fatty acid receptor 2; microbiota; metabolite; sensor; G-coupled protein receptor; signaling; Alzheimer’s disease; senescence; C. elegans
Online: 24 December 2020 (14:56:00 CET)
HYPOTHESIS
|
doi:10.20944/preprints202401.0111.v2
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Cancer; cellular senescence; telomere attrition; alternative telomere lengthening; PML nuclear bodies; lamin B1; ALU; surface heterochromatin; nuclear rotation; chromothripsis
Online: 5 January 2024 (10:06:39 CET)
ARTICLE
|
doi:10.20944/preprints202408.0878.v1
Subject:
Environmental And Earth Sciences,
Sustainable Science And Technology
Keywords:
Bio-fertilizer; Bio-stimulant; Plant growth promoting bacteria; Leaf senescence; Stomatal conductance; Sustainable agriculture; Nitrogen-fixing bacteria; Methylobacterium symbioticum; wheat.
Online: 13 August 2024 (11:30:58 CEST)
REVIEW
|
doi:10.20944/preprints202308.0733.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
chronic kidney disease; uremic toxins; renal tubular transport; extracellular matrix remodeling; apoptosis resistance; inflammatory response; senescence-associated secretory phenotype factors
Online: 9 August 2023 (10:49:19 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202109.0437.v2
Subject:
Biology And Life Sciences,
Aging
Keywords:
Alzheimer's; Cellular senescence; Neurodegeneration; Microglia; Astrocytes; Oligodendrocyte Progenitor Cells; TREM2; Braak staging; Oxidative stress; Phapoptosis; Amyloid-beta; Tau; Neuritic plaques
Online: 7 March 2022 (14:22:25 CET)
REVIEW
|
doi:10.20944/preprints202103.0245.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
early life adversity; stress; psychosocial stress; hypothalamus-pituitary-adrenal axis; ageing; immuno-senescence; inflammageing; Developmental origins of health and disease
Online: 9 March 2021 (09:26:00 CET)
REVIEW
|
doi:10.20944/preprints202404.1322.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
solid tumor therapy; intratumor heterogeneity; polyploid giant cancer cells; senescence; anastasis; oncogenic caspases; Phoenix Rising; treacherous apoptosis; preclinical assays; precision oncology
Online: 22 April 2024 (08:33:06 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1783.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
human mesenchymal stem cells; mesenchymal to epithelial transition (MET); epithelial to mesenchymal transition (EMT); HAND2; HAND2-AS1; senescence; stem cell plasticity
Online: 26 September 2023 (10:46:24 CEST)
REVIEW
|
doi:10.20944/preprints202012.0795.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
T cells; chimeric antigen receptor; transgenic T-cell receptor; tumor-infiltrating lymphocytes; exhaustion; terminal differentiation; senescence; apoptosis; adoptive cell transfer; immunotherapy
Online: 31 December 2020 (12:16:55 CET)
ARTICLE
|
doi:10.20944/preprints202307.1220.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
age-related macular degeneration; aging retina; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1 AMD; cellular senescence; autophagy; oxidative stress
Online: 18 July 2023 (11:09:42 CEST)