ARTICLE
|
doi:10.20944/preprints202312.0648.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
uterine myoma; Angiopoietin 1; Calcium sensing receptor; Focal Adhesion Kinase
Online: 11 December 2023 (06:03:40 CET)
ARTICLE
|
doi:10.20944/preprints202312.0574.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
DOCK program; GOLD program; Grb14; insulin receptor (IR); structure-based drug screening (SBDS)
Online: 8 December 2023 (08:24:15 CET)
REVIEW
|
doi:10.20944/preprints202312.0514.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Macrophage; polarization; receptor; bacteria; virus; fungi; parasites
Online: 8 December 2023 (07:39:15 CET)
ARTICLE
|
doi:10.20944/preprints202312.0256.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
Novichok; AChE; DFT; binding affinity
Online: 5 December 2023 (14:59:21 CET)
REVIEW
|
doi:10.20944/preprints202312.0050.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
DNA Replication; DNA repair; homologous recombination; DNA damage signalling; replication protein A, DNA binding; protein interactions
Online: 1 December 2023 (05:44:23 CET)
REVIEW
|
doi:10.20944/preprints202311.2011.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
allogeneic; chimeric antigen receptor; off-the-shelf; gene editing
Online: 1 December 2023 (03:05:54 CET)
ARTICLE
|
doi:10.20944/preprints202311.1891.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
Eruca sativa; Skin barrier function; Peroxisome proliferator activated receptor-α ; Anti-inflammation; Docking simulation
Online: 29 November 2023 (12:16:32 CET)
REVIEW
|
doi:10.20944/preprints202311.1826.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Breast cancer; Estrogen receptor-positive; endocrine therapies; resistance; selective estrogen degrades; Oral
Online: 29 November 2023 (08:15:18 CET)
ARTICLE
|
doi:10.20944/preprints202311.1740.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Interleukin-6 receptor; colorectal carcinoma; xenograft; Tocilizumab; Ki-67; ERK 1/2; STAT3
Online: 28 November 2023 (03:43:13 CET)
REVIEW
|
doi:10.20944/preprints202311.1691.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
synephrine; glucocorticoids; selective glucocorticoid receptor activator (SEGRA); inflammation; cancer; CpdA; metabolic disorders; cardiovascular system; beta-adrenergic receptors
Online: 27 November 2023 (09:16:53 CET)
ARTICLE
|
doi:10.20944/preprints202311.1617.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Chromatin immunoprecipitation followed by sequencing; transcription factors binding sites prediction; cooperative binding of transcription factors; motifs conservation; classification of transcription factors; direct binding of transcription factors
Online: 27 November 2023 (07:26:54 CET)
ARTICLE
|
doi:10.20944/preprints202311.1542.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
IL-1R; Interleukin– 1 receptor; Il-1 receptor; Glycyrrhiza glabra; Licorice; Flavonoid; Inflammation; Periodontitis; Molecular docking; In silico
Online: 24 November 2023 (02:39:37 CET)
REVIEW
|
doi:10.20944/preprints202311.1503.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
receptor-type protein tyrosine phosphatases (RPTPs); CD148; R3 subgroup; Extracellular domain (ECD); Fibronectin; Polymorphisms; AlphaFold
Online: 23 November 2023 (10:53:39 CET)
ARTICLE
|
doi:10.20944/preprints202311.1397.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
toll-like receptor (TLR) agonist; TLR4; TLR7/8; adjuvants; alhydrogel; adju-phos; SARS-CoV-2; COVID-19
Online: 22 November 2023 (14:34:17 CET)
REVIEW
|
doi:10.20944/preprints202311.1315.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Vitamin D receptor (VDR); Epigenetics; DNA methylation; VDR-related diseases
Online: 21 November 2023 (10:47:16 CET)
ARTICLE
|
doi:10.20944/preprints202311.1044.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Quercetin; antiemetic; molecular docking; D2 receptor; toxicity
Online: 16 November 2023 (11:16:44 CET)
ARTICLE
|
doi:10.20944/preprints202311.1067.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
Non-melanoma skin cancer; Vitamin D; risk; Vitamin D receptor; review; VDR polymorphism
Online: 16 November 2023 (10:46:20 CET)
ARTICLE
|
doi:10.20944/preprints202311.0981.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Bacteriophage; Genome sequence; Diversity-generating retroelement; C-type lectin; Tentaclin; Adhesin; Ig-like domain; Receptor-binding protein
Online: 15 November 2023 (09:55:37 CET)
ARTICLE
|
doi:10.20944/preprints202311.0853.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
liquid-liquid phase separation; membrane-less organelles; stress granules; P-bodies; intrinsically disordered proteins; intrinsically disordered regions; aging; senescence; protein aggregation; nucleic acids; RNA-binding protein; DNA-binding protein
Online: 14 November 2023 (16:38:59 CET)
ARTICLE
|
doi:10.20944/preprints202311.0851.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Estrogen receptor a; sigma receptors; TMEM97; mTOR; S6K1; tamoxifen.
Online: 14 November 2023 (09:28:12 CET)
ARTICLE
|
doi:10.20944/preprints202311.0832.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
G protein-coupled receptor; cell trafficking; endoplasmic reticulum; ERES; escort protein; gatekeeper; biosensor; BRET
Online: 14 November 2023 (07:48:13 CET)
ARTICLE
|
doi:10.20944/preprints202311.0522.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Rabson-Mendenhall syndrome; insulin resistance; diabetes mellitus; acanthosis nigricans; tyrosine kinase; insulin; Insulin receptor; INSR
Online: 8 November 2023 (07:35:08 CET)
ARTICLE
|
doi:10.20944/preprints202311.0296.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
SARS-CoV-2; Variants; Spike Glycoprotein; Receptor Binding Motif, Receptor Binding Domain; Neutralizing Antibodies; Ig subclasses; IgG; IgA
Online: 7 November 2023 (11:27:48 CET)
ARTICLE
|
doi:10.20944/preprints202311.0414.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
Perilla frutescens var. acuta; Anti-inflammation; Peroxisome proliferator-activated receptor; Nu-clear factor kappa B; Flavonoid diglucuronide
Online: 7 November 2023 (08:25:51 CET)
REVIEW
|
doi:10.20944/preprints202311.0301.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
α-synuclein; Parkinson’s disease; mitochondria; melatonin; glucocorticoid receptor; aryl hydrocarbon receptor; TrkB; gut microbiome; circadian; treatment
Online: 7 November 2023 (02:28:54 CET)
ARTICLE
|
doi:10.20944/preprints202311.0266.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
Lung neoplasm, early stage, epidermal growth factor receptor
Online: 6 November 2023 (09:26:40 CET)
ARTICLE
|
doi:10.20944/preprints202311.0317.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
systemic lupus erythematosus; serum soluble transferrin receptor; interleukin 4; organ manifestations
Online: 6 November 2023 (07:52:16 CET)
ARTICLE
|
doi:10.20944/preprints202310.1965.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Farnesoid X receptor; gut microbiota; intestinal epithelial barrier; colon cancer; Klotho; fibroblast growth factor
Online: 30 October 2023 (16:39:45 CET)
ARTICLE
|
doi:10.20944/preprints202310.1912.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Glioblastoma; cancer stem cells; M2 muscarinic receptor; orthosteric and dualsteric muscarinic agonism; autophagy; apoptosis; mTORC1
Online: 30 October 2023 (13:57:53 CET)
ARTICLE
|
doi:10.20944/preprints202310.1622.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
mRNA delivery; adenovirus; Catcher/Tag bioconjugation; RNA binding protein; mRNA condensation; vaccine
Online: 25 October 2023 (10:31:41 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1592.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
α-synuclein aggregates; 4,4'-diarylbisthiazole; binding affinity; Hantzsch thiazole synthesis; lipophilicity; O-fluoroethylation; O-fluoroPEGylation; O-methylation
Online: 25 October 2023 (08:36:57 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1476.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
piceatannol; hormone-sensitive lipase; adipocyte; lipolysis; G protein coupled-estrogen receptor (GPER)
Online: 24 October 2023 (07:50:51 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1385.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
analgesia; antinociception; interleukin-31 (IL-31); interleukin receptor A (IL-31RA); IL-31 receptor A-deficient (IL-31RAKI) mice; itch; morphine; pain
Online: 23 October 2023 (10:11:31 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1322.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Drynaria fortunei-derived polysaccharides; bone marrow-derived macrophages; osteoclastogenesis; receptor activator of nuclear factor-κB ligand; nuclear factor of activated T cells 1
Online: 20 October 2023 (12:08:32 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1074.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
mixed-based combinatorial library; structure–activity relationships; cyclic peptide; mu-opioid receptor; delta-opioid receptor; bifunctional ligand; antinociception; opioid antagonist; opioid liabilities
Online: 17 October 2023 (11:21:32 CEST)
ARTICLE
|
doi:10.20944/preprints202310.0978.v1
Subject:
Medicine And Pharmacology,
Otolaryngology
Keywords:
paranasal sinus; chronic rhinosinusitis; CRS; epithelial cell; eosinophil; oncostatin M; OSM; OSM receptor; OSMR
Online: 17 October 2023 (08:05:36 CEST)
REVIEW
|
doi:10.20944/preprints202310.0928.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
naphtoquinones; Parkinson disease; P2X7 receptor
Online: 16 October 2023 (08:43:32 CEST)
REVIEW
|
doi:10.20944/preprints202310.0850.v1
Subject:
Medicine And Pharmacology,
Reproductive Medicine
Keywords:
sirtuin-1; SIRT1; sirtuins; human placenta; placental physiology; placental pathophysiology; preeclampsia; peroxisome proliferator-activated receptor γ; PPARγ; SIRT1/PPARγ signaling
Online: 13 October 2023 (07:58:19 CEST)
REVIEW
|
doi:10.20944/preprints202310.0848.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
ribosomal origins and evolution; RNA binding proteins; ribosomal RNA; ribosomopathies
Online: 13 October 2023 (07:56:18 CEST)
REVIEW
|
doi:10.20944/preprints202310.0577.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Androgen Receptor, AR signaling, Prostate cancer, SRC-3, Therapeutics
Online: 11 October 2023 (07:43:18 CEST)
REVIEW
|
doi:10.20944/preprints202310.0213.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNA; RNA binding proteins; RNA modifications; RNA-protein interactions; review
Online: 10 October 2023 (10:12:09 CEST)
ARTICLE
|
doi:10.20944/preprints202310.0601.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
leucine-rich repeat; variable lymphocyte receptor; hybrid LRR technique; surface plasmon resonance analysis; flagellin
Online: 10 October 2023 (07:59:25 CEST)
REVIEW
|
doi:10.20944/preprints202310.0551.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
Diabetes; Chronic Kidney Disease; Treatment; Elderly; Geriatric; Dialysis; SGLT2 inhibitors; GLP1 Receptor Agonists; Non-steroidal Mineralocorticoid Antagonists
Online: 9 October 2023 (16:56:30 CEST)
REVIEW
|
doi:10.20944/preprints202310.0345.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Prostate cancer, SPOP mutations, Androgen Receptor, disease characterization, therapeutic targets
Online: 6 October 2023 (11:29:08 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1992.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Cotton leaf curl Kokhran virus; microRNAs; RNA interference; prediction; computational algorithms; target binding sites; host-virus interaction
Online: 28 September 2023 (18:36:58 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1984.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
chronic kidney disease; biomarkers; urinary liver type fatty acid binding protein; urinary protein to creatinine ratio
Online: 28 September 2023 (10:17:35 CEST)
REVIEW
|
doi:10.20944/preprints202309.1583.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
lipopolysaccharide (LPS, endotoxin), LPS-binding proteins/peptides, host defence proteins/peptids, innate immune system, marine invertebrates, Gram-negative sepsis, endotoxic shock.
Online: 26 September 2023 (08:12:49 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1706.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
isoxazolidine derivatives; 1,3-dipolar cycloaddition; α-aryl-N-methyl nitrones; Density Functional Theory (DFT); Electron Localization Function (ELF); CDFT indices; docking; molecular dynamics; EGFR; binding energy
Online: 26 September 2023 (04:37:56 CEST)
REVIEW
|
doi:10.20944/preprints202305.0720.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Prostate cancer; androgen receptor; AR signaling pathway; disease progression; therapeutic re-sistance; personalized treatment; androgen deprivation therapy; AR-targeted therapies
Online: 25 September 2023 (16:46:10 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1606.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Vitamin D; Vitamin D receptor (VDR); Sirtuin; Sarcopenia; Muscle atrophy; Mitochondrial Biogenesis; Oxidative Phosphorylation (OXPHOS)
Online: 25 September 2023 (12:55:47 CEST)
REVIEW
|
doi:10.20944/preprints202309.1647.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
macrophage; inflammation; acetylcholine receptor; cholinergic receptor; polarization, cholinergic agonist; alpha 7 nicotinic acetylcholine receptor; CHRFAM7A, cholinergic machinery, cholinergic anti-inflammatory pathway
Online: 25 September 2023 (09:28:51 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1613.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
SARS-CoV-2; Immune response; Maternal-fetal IgG transference; Antibody Functionality; Antibody persistence; IFN-Y and IL-4 secretion; Receptor Binding Domain (RBD); Outer Membrane Vesicles (OMV); Saponin; Dioctadecyldimethylammonium Bromide (DDA); ELISpot
Online: 25 September 2023 (04:39:59 CEST)
REVIEW
|
doi:10.20944/preprints202309.1372.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
oleanolic acid; nuclear receptors; metabolic disorders; NASH; farnesoid X receptor; liver X receptor; peroxisome-proliferator activated receptors
Online: 21 September 2023 (03:12:08 CEST)
REVIEW
|
doi:10.20944/preprints202309.1184.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
frontotemporal lobar degeneration; transactive response DNA‐binding protein 43; limbic age related encephalopathy; progranulin
Online: 19 September 2023 (07:39:10 CEST)
REVIEW
|
doi:10.20944/preprints202309.1180.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
myeloma; daratumumab; bispecific antibodies; chimeric antigen receptor T-cells; immunotherapy
Online: 19 September 2023 (05:28:58 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1130.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
ice nucleation; freezing; melting; ice-binding proteins; antifreeze proteins; ice nucleators; supercooling; ice-binding surfaces
Online: 18 September 2023 (14:00:40 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0917.v1
Subject:
Physical Sciences,
Quantum Science And Technology
Keywords:
quantum tunneling; quasi bound states; tight binding lattices
Online: 14 September 2023 (03:42:42 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0886.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
nuclear periodicity; nuclear structure; shell model; nucleon pairing effect; quark structure; representational nuclear chemistry; nucleon binding energy; nuclear magnetic moment
Online: 13 September 2023 (11:13:57 CEST)
REVIEW
|
doi:10.20944/preprints202309.0856.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Penicillin-binding protein 2a (PBP2a); Mur enzymes; heterocycles; High-throughput screenings; transpeptidation
Online: 13 September 2023 (09:01:12 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0748.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
SARS-CoV-2; coronavirus; monoclonal antibodies; resistance; nanopore; Sweden; whole-genome sequencing; receptor binding domain
Online: 12 September 2023 (11:14:08 CEST)
REVIEW
|
doi:10.20944/preprints202309.0711.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Cancer Stem Cell; Androgen Receptor; Prostate Cancer; Breast Cancer; Glioblastoma
Online: 12 September 2023 (03:15:45 CEST)
REVIEW
|
doi:10.20944/preprints202309.0633.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
metastatic hormone-sensitive prostate cancer; new hormonal agents; transcriptomic profiling; DNA damage repair genes; tumor suppressor genes; androgen receptor; immunotherapy; CDK4/6 inhibitors; PARP inhibitors; AKT inhibitors.
Online: 11 September 2023 (07:17:07 CEST)
REVIEW
|
doi:10.20944/preprints202309.0573.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Calcium; Ca2+ channels; Ca2+ pumps; Ca2+ binding proteins (CaBPs); Plant growth-promoting rhizobacteria
Online: 8 September 2023 (09:52:51 CEST)
REVIEW
|
doi:10.20944/preprints202309.0470.v1
Subject:
Medicine And Pharmacology,
Dentistry And Oral Surgery
Keywords:
VitD; VitD receptor; OPMD; SCC; premalignancy; white lesions; red lesions
Online: 7 September 2023 (10:28:03 CEST)
REVIEW
|
doi:10.20944/preprints202309.0428.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
NK1 receptor; Substance P; Neuroinflammation; Blood-brain barrier; Traumatic brain injury; Stroke; CNS infection; NK1 receptor antagonist
Online: 7 September 2023 (03:59:49 CEST)
REVIEW
|
doi:10.20944/preprints202309.0451.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
Acute myeloid leukemia (AML); childhood; Core-binding factor (CBF); KMT2A/11q23 rearrangement; acute promyelocytic leukemia (APL); hematopoietic stem cell transplantation (HSCT)
Online: 6 September 2023 (15:38:49 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0347.v1
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
Fasciola hepatica; triclabendazole; anthelmintic-resistance; amino acid-substitution; binding-pocket; ligand-protein docking; protein 3D modeling.
Online: 6 September 2023 (10:24:35 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0292.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
bone mineral markers; phosphate/calcium homeostasis; dialysis; inflammation; mortality; vitamin D receptor polymorphism; diabetes; vascular calcification; hs-CRP; CKD
Online: 6 September 2023 (03:34:19 CEST)
REVIEW
|
doi:10.20944/preprints202309.0353.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
FDA; Omics technology; Pharmacodynamic biomarkers; biosimilars; Proteomics; Gycomis; Re-ceptor Binding; Pharmacokinetics
Online: 6 September 2023 (03:32:11 CEST)
REVIEW
|
doi:10.20944/preprints202309.0306.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
glucocorticoid receptor; glaucoma; animal models; anti-inflammatory steroids; primary open-angle glaucoma; steroid glaucoma; ocular hypertension; eye
Online: 6 September 2023 (02:34:47 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202309.0196.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Neurodegenerative disorders; schizophremia; PDK1 inhibitors; Lipid replacement therapy; Aryl hydrocarbon receptor antagonists
Online: 4 September 2023 (14:29:13 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0113.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Post-Acute COVID-19 Vaccination Syndrome; PACVS, G-protein-coupled receptor; receptor antibody; interleukin-6; dis-autonomy; chronic fatigue.
Online: 4 September 2023 (07:14:41 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1827.v1
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
Pseudomonas syringae; methyl‐accepting chemotaxis protein; Caenorhabditis elegans; receptor protein; nematicidal activity
Online: 29 August 2023 (04:14:35 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1858.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Deep Learning, ELECTRA; Ion binding site prediction; Transformer; Natural Language Processing; Sequence-based prediction
Online: 29 August 2023 (02:50:38 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1086.v2
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
SAXS; conformational change; plasminogen; fibrinolysis; structure-function; lysine binding site; lysine analogue; kringle domain
Online: 23 August 2023 (09:57:06 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1611.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Cancer; Multiple Myeloma; Natural Killer; Immunotherapy; Chimeric Antigen Receptor; Allogenic
Online: 23 August 2023 (08:48:43 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1603.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Multiplicity of infection; cell density at infection; SARS-CoV-2; Spike S1 glycoprotein; Receptor binding domain; Sf9 cells
Online: 23 August 2023 (07:53:03 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1524.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
cysteine-rich peptides; cell penetration; microproteins; metal-binding peptides; coffee waste product; chemical synthesis; hevein-like peptide; non-chitin binding hevein; ginsentide
Online: 22 August 2023 (09:35:21 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1495.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
cannabidiol; cannabis; adverse reaction; adverse event; pharmacovigilance; serotonin; 5-HT1A receptor
Online: 22 August 2023 (07:49:03 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1485.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; pathologic complete response; tumour-infiltrating lymphocytes; neoadjuvant systemic therapy; CD8 antigen; forkhead box P3; programmed cell death 1 receptor; chemokine CXCL13
Online: 22 August 2023 (07:32:48 CEST)
REVIEW
|
doi:10.20944/preprints202308.1518.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
SARS-CoV-2; main protease; inhibitors; molecular modeling; molecular dynamics simulations; binding energy calculation; ADME properties; potential therapeutics; drug discovery
Online: 22 August 2023 (07:19:37 CEST)
REVIEW
|
doi:10.20944/preprints202308.1470.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Growth hormone receptor (GHR); Human growth hormone; Deletion of exon 3 (d3GHR); Polymorphism; Growth and development; Hormone deficiency
Online: 21 August 2023 (11:59:26 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1414.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
PNA6; angiotensin 1-7; Mas receptor; breast; cancer; pain
Online: 21 August 2023 (07:18:07 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1296.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
mammalians; spinal cord; central canal; CSF; CSF-cNs; intrinsic sensory neurons; transient receptor potential channels
Online: 18 August 2023 (10:59:31 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1185.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
Obstructive sleep apnea; irisin; retinol-binding protein-4; adiponectin; apnea hypopnea index
Online: 16 August 2023 (08:25:16 CEST)
REVIEW
|
doi:10.20944/preprints202308.1013.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Neurokin-1 receptor; substance P; tachykinin; thyroid gland; thyroid cancer
Online: 14 August 2023 (10:23:07 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0940.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Chinese indigenous pig; insulin-like growth factors; receptors; binding protein; weaning
Online: 11 August 2023 (11:08:52 CEST)
REVIEW
|
doi:10.20944/preprints202308.0821.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
ligand-free receptor signaling; inverse agonist; neutral antagonist; μ opioid receptor; opioid dependence; 6β-naltrexol; psychedelics; LSD; 5-HT2A; GHSR
Online: 10 August 2023 (09:48:03 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0488.v2
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
COVID-19; Receptor binding domain (RBD); natural infection; vaccination; neutralizing antibodies
Online: 8 August 2023 (07:11:22 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0544.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
TRIM6; Gliomas; Prognostic Biomarker; Cytokine-cytokine receptor interaction; Immune Infiltrates
Online: 7 August 2023 (11:48:02 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0395.v1
Subject:
Environmental And Earth Sciences,
Water Science And Technology
Keywords:
Grafted hydrogel; Ground water; Ammonia and Iron removal efficiency; DFT and MEP; binding Energy
Online: 4 August 2023 (11:32:16 CEST)
REVIEW
|
doi:10.20944/preprints202308.0434.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
In silico studies; drug discovery; SARS-CoV-2; molecular docking; virtual screening; molecular dynamics simulations; drug candidates; antiviral activity; receptor-ligand complex; drug design
Online: 4 August 2023 (11:11:21 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0290.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNA-binding protein; human antigen R (HuR); high-throughput virtual screening; small molecule inhibitors; RNA pulldown assay
Online: 3 August 2023 (10:11:15 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0183.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
bacterial diversity; gut microbiota; prolactin receptor; lactation; weaning
Online: 2 August 2023 (08:46:06 CEST)
ARTICLE
|
doi:10.20944/preprints202307.2027.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
nuclear receptor; small heterodimer partner (SHP); knockout; macrophage; differentiation
Online: 31 July 2023 (10:24:05 CEST)
ARTICLE
|
doi:10.20944/preprints202307.2015.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
L,D-peptidase; bacteriophage; catalysis; substrate binding; calcium
Online: 28 July 2023 (12:29:31 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1961.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
fremanezumab; monoclonal antibody; calcitonin gene-related peptide; trigeminal ganglion; CGRP receptor; immunofluorescence; rat; migraine pain
Online: 28 July 2023 (09:27:07 CEST)
COMMUNICATION
|
doi:10.20944/preprints202307.1930.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
CETP; atherosclerosis; inflammation; macrophages; nicotinamide nucleotide transhydrogenase; LDL receptor knockout mice
Online: 27 July 2023 (13:38:57 CEST)
REVIEW
|
doi:10.20944/preprints202307.1409.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
spinal and bulbar muscular atrophy; antisense therapy; oligonucleotide; splice switching; mRNA knockdown; androgen receptor; AR45
Online: 20 July 2023 (09:53:18 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1220.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
age-related macular degeneration; aging retina; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1 AMD; cellular senescence; autophagy; oxidative stress
Online: 18 July 2023 (11:09:42 CEST)