ARTICLE
|
doi:10.20944/preprints202002.0071.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
2019-nCoV; novel corona virus; Wuhan virus; drug; vaccine; spike protein; epitope; vaccine design
Online: 5 February 2020 (15:34:15 CET)
ARTICLE
|
doi:10.20944/preprints202311.1460.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
Onchocerciasis; drug discovery; anthelmintics; O. gutturosa; motility and MTT inhibition; FDA approved drugs
Online: 23 November 2023 (09:31:11 CET)
ARTICLE
|
doi:10.20944/preprints202401.1509.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
HCV; cascade of care; therapeutic community; intravenous drug use
Online: 19 January 2024 (14:43:54 CET)
ARTICLE
|
doi:10.20944/preprints202304.0569.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Olaparib; self-microemulsifying drug delivery system; microemulsion; solubility; dissolution; oral absorption
Online: 19 April 2023 (08:16:05 CEST)
REVIEW
|
doi:10.20944/preprints202206.0333.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
hPSCs derived-organoids; Culture strategy; Disease modeling; Drug screening; Regenerative therapy
Online: 24 June 2022 (08:11:15 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0236.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
essential oils; drug resistant microorganisms; antimicrobial activity; antifungal activity; medicinal plants
Online: 11 October 2018 (11:51:16 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1198.v1
Subject:
Environmental And Earth Sciences,
Oceanography
Keywords:
multi-drug resistant bacteria; microbial treatment; coastal organic waste; Pseudomonadale; marine microorganisms
Online: 18 April 2024 (08:10:05 CEST)
REVIEW
|
doi:10.20944/preprints202402.0148.v1
Subject:
Medicine And Pharmacology,
Dentistry And Oral Surgery
Keywords:
medication-related osteonecrosis of the jaw; drug holiday; treatment; tooth extraction; incidence
Online: 2 February 2024 (11:48:46 CET)
ARTICLE
|
doi:10.20944/preprints202003.0413.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
coronavirus; drug; COVID-19; SARS; MERS; ontology; ChEBI; NDF-RT; DrON; bioinformatics
Online: 29 March 2020 (01:58:40 CET)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
gas chromatography mass spectrometry; metabolomics; acute lymphoblastic leukemia; confocal microscopy; high-throughput drug screens; VAST
Online: 7 June 2021 (08:01:21 CEST)
REVIEW
|
doi:10.20944/preprints202008.0320.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Data Science; Machine Learning; Deep Learning; Genomics; COVID-19; Drug Discovery; Image Analysis; Interactomics; Epidemiology
Online: 14 August 2020 (11:01:56 CEST)
COMMUNICATION
|
doi:10.20944/preprints202306.2160.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
delayed drug hypersensitivity; skin reaction; SARS-CoV-2; LTT; interleukins
Online: 29 June 2023 (13:57:05 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0292.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer's disease; BACE1; Molecular dynamics; MM/GBSA; Inhibitors; Drug likeness; Ligand efficiency, Kd.
Online: 10 November 2020 (09:10:50 CET)
ARTICLE
|
doi:10.20944/preprints202404.0199.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
follicular thyroid neoplasia; PAX8– PPARγ fusion; fusion protein; structure-based drug design
Online: 3 April 2024 (07:24:16 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0667.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Ovarian cancer; drug resistance; apoptosis; proteomics; combination; cytotoxicity; artemisinin; oleanolic acid; platinum drugs; cisplatin
Online: 30 August 2020 (12:06:32 CEST)
REVIEW
|
doi:10.20944/preprints202008.0729.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
p53; p73; MDM2; MDMX; tumor suppressor; drug repurposing; aspirin; protoporphyrin IX; verteporfin
Online: 17 September 2020 (07:23:37 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1661.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
adherence; adverse drug reactions; type 2 diabetes mellitus; therapy
Online: 24 August 2023 (03:49:56 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0447.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
spike protein; SARS-CoV-2; mutation; drug repurposing; digitoxin
Online: 20 August 2020 (08:24:41 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0090.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
arterial vessel; bound drug; DamKöhler number; diffusivity; finite volume; free drug; internalized drug; stent; Pecklet number; poly(lactic-co-glycolic acid); porosity; scalar; species; tortuosity; transport
Online: 3 May 2023 (03:14:33 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0090.v1
Subject:
Computer Science And Mathematics,
Computational Mathematics
Keywords:
epithelial cell; antibody response; basic reproduction number; transcritical bifurcation; impulsive control; drug holidays
Online: 6 September 2022 (10:25:07 CEST)
REVIEW
|
doi:10.20944/preprints202306.1921.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Antibiotic resistance; Drug designing; Bacterial mutation; Bacterial evolution; Horizontal gene transfer; Public and agricultural health
Online: 27 June 2023 (13:55:21 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0914.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Metformin; Quorum sensing; Quorum quenching; Pseudomonas aeruginosa; Virulence; Drug repurposing; Anti-virulence therapy; Biofilm inhibition
Online: 25 April 2023 (09:54:20 CEST)
ARTICLE
|
doi:10.20944/preprints201905.0370.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Targeted drug delivery, VX2 tumor, breast cancer, cryoablation, cryo-assisted injection, cryo-assisted resection, blue dye, epirubicin.
Online: 30 May 2019 (13:44:41 CEST)
ARTICLE
|
doi:10.20944/preprints202312.2016.v2
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
interpolyelectrolyte complexes; Eudragit® ; gastroretentive systems; drug delivery systems; bioadhesive systems; metronidazole; acyclovir
Online: 27 December 2023 (14:28:59 CET)
REVIEW
|
doi:10.20944/preprints201910.0296.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
nasal delivery; glioblastoma multiforme; drug delivery; nanoparticles; nose-to-brain delivery; pre-clinical studies; clinical evaluation
Online: 27 October 2019 (09:36:27 CET)
ARTICLE
|
doi:10.20944/preprints202310.1539.v1
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
graph neural network; convolutional neural network; drug-target affinity; sequence and structural knowledge; heterogeneous models
Online: 25 October 2023 (08:23:34 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1427.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
pulmonary tuberculosis, Mycobacterium tuberculosis, alveolar macrophages, drug tolerance, persistence, dormancy, biomarkers, non-acid-fastness, Rv2623
Online: 21 August 2023 (12:11:01 CEST)
REVIEW
|
doi:10.20944/preprints202306.1176.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
lung cancer; organoid; drug screening; high throughput; translational; pre-clinical; clinical; tumor microenvironment; personalized medicine
Online: 16 June 2023 (08:42:28 CEST)
REVIEW
|
doi:10.20944/preprints202010.0179.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Non Michaelis-Menten Kinetics; High-throughput screening; allostery; cooperativity; processive kinetics; distributive kinetics; single-molecule; auto-catalytic; drug discovery
Online: 8 October 2020 (13:34:16 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0310.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
primary open angle glaucoma; dorzolamide/timolol fixed combination; drug efficacy; safety
Online: 24 April 2018 (08:36:58 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0490.v1
Subject:
Computer Science And Mathematics,
Computer Vision And Graphics
Keywords:
drug release simulation; disintegration simulation; poorly water soluble drug; mefenamic acid; Noyes-Whitney equation; cellular automata; synchrotron microtomography
Online: 22 October 2018 (11:38:04 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1579.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Multiple Drug Resistant breast cancer; Anaphase Promoting Complex; cell culture; PDX mouse model
Online: 28 March 2024 (13:34:15 CET)
REVIEW
|
doi:10.20944/preprints202405.0601.v1
Subject:
Life Sciences,
Biology And Life Sciences
Keywords:
Data science; Big data; Data mining; Bioinformatics; Chemometric; Medicinal chemistry; Targets; Knowledge discovery; Artificial intelligence, Machine learning, Deep learning; Data integration; Metadata, Database; QSAR; Collaborative drug discovery; Structure-based drug design; Ligand-based drug discovery; Clinical trials; Product development.
Online: 10 May 2024 (10:15:20 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1209.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Mycobacterium tuberculosis; Drug Resistance; Whole Genome Sequencing; Genetic Diversity; Brazil; Novel Mutations
Online: 18 April 2024 (07:51:01 CEST)
ARTICLE
|
doi:10.20944/preprints202201.0082.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; cancer stem cell; therapy resistance; cationic amphiphilic drug; lysosome-dependent cell death
Online: 6 January 2022 (11:51:28 CET)
REVIEW
|
doi:10.20944/preprints202305.0289.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
cancer therapy; nanomedicine; drug delivery; pH-responsiveness; EPR; intratumoral delivery; intracellular delivery; nanoparticles; metal-organic frameworks
Online: 5 May 2023 (03:45:54 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0224.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Keywords: Model; Drug resistance TB, Collaboration and Integration
Online: 3 August 2023 (08:17:13 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0524.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
unsupervised learning; tensor decomposition; feature selection; COVID-19; drug discovery; gene expression
Online: 3 June 2020 (05:29:09 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0783.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
poly(-caprolactone); electrospinning; nano-hydroxyapatite; Humulus lupulus; hops; drug delivery system; bone regeneration
Online: 13 March 2024 (16:05:00 CET)
ARTICLE
|
doi:10.20944/preprints202311.0316.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
levofloxacin; human serum albumin; hydroxypropyl-β-cyclodextrin; conjugate; drug delivery systems; antibacterial activity
Online: 6 November 2023 (07:51:27 CET)
ARTICLE
|
doi:10.20944/preprints201908.0253.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
halogen bonding; fluorine; iodine; pentafluorosulfanyl; titration; ab initio calculation; NMR study; drug design
Online: 25 August 2019 (15:41:59 CEST)
ARTICLE
|
doi:10.20944/preprints202112.0296.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Plasmodium falciparum dihydroorotate dehydrogenase; fragment-based drug design; 2D-QSAR; DFT calculation; Lead optimization; Induced Fit docking
Online: 20 December 2021 (09:39:42 CET)
ARTICLE
|
doi:10.20944/preprints202403.0750.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Hepatitis B virus; drug resistance; people living with HIV; Botswana; Africa
Online: 13 March 2024 (11:38:15 CET)
ARTICLE
|
doi:10.20944/preprints202401.1186.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
kidney replacement therapy; medication review; drug-related problems; negative outcomes associated with medication.
Online: 16 January 2024 (13:57:35 CET)
ARTICLE
|
doi:10.20944/preprints201908.0177.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
chronic myeloid leukemia; tyrosine kinase inhibitor; adverse drug event; quality of life; second-generation tyrosine kinase inhibitor; nilotinib
Online: 16 August 2019 (08:09:07 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0156.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
antimicrobial resistance; biosecurity; dairy calves; ESBL E. coli; multi-drug resistant; waste milk
Online: 2 February 2024 (14:20:05 CET)
ARTICLE
|
doi:10.20944/preprints202212.0368.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Betulinic acid; bovine serum albumin; doxorubicin; drug delivery system; lung cancer; synergistic effect.
Online: 20 December 2022 (10:40:12 CET)
REVIEW
|
doi:10.20944/preprints202008.0312.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
SARS-CoV-2(COVID-19); + ssRNA; ribosomal – framshift; Pseudoknot; replication; model; drug; vaccine
Online: 14 August 2020 (08:26:31 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0431.v1
Subject:
Social Sciences,
Psychology
Keywords:
alcohol use; drug use; adolescents; adults; health variables; South Africa
Online: 16 November 2020 (15:36:53 CET)
REVIEW
|
doi:10.20944/preprints202306.1209.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
End-stage renal disease; medication review; drug-related problems; negative outcomes associated with medication.
Online: 16 June 2023 (10:13:13 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
metabolic functionalization of alkyl moieties in drug molecules; structure influence on metabolic functionalization of alkyl moieties; mechanism of alkyl free radical hydroxy functionalization; pharmacologic activity of hydroxy and carboxy functionalized alkyl moieties in drug molecules; primary and auxiliary pharmacophores; auxophores
Online: 11 March 2020 (03:20:58 CET)
ARTICLE
|
doi:10.20944/preprints202307.0133.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Hydrophilic polymers; Thermo-responsive polymers; Polymer drug delivery system; Tumor-specific targeting; Recombinant proteins; Non-covalent attachment; Tris(nitrilotriacetic acid) ligation
Online: 4 July 2023 (08:01:27 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1647.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
non-steroidal anti-inflammatory drug; stroke; acute coronary syndrome; myocardial infarction; mortality; readmission; Arabian Gulf
Online: 25 July 2023 (08:26:22 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0440.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; SARS-CoV-2; 2019-nCoV; novel corona virus; drug repurposing; chloroquine; high-risk group; asymptomatic
Online: 30 March 2020 (07:24:16 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1334.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
victimizing and perpetrating violence; interpersonal and intimate violence; harmful alcohol and drug use; mental health symptoms; paths of violence; gender
Online: 18 May 2023 (10:46:13 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0490.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
CD44; Cancer Stem Cells; Tumorigenesis; Drug Resistance; Immune Markers; Epithelial to Mesenchymal Transition; Therapeutic Targeting
Online: 25 January 2021 (12:23:49 CET)
REVIEW
|
doi:10.20944/preprints202007.0016.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
myeloma; BCMA; bispecific T-cell engager; antibody-drug conjugates; chimeric antigen receptor T-cells; belantamab mafodotin; idecabtagene vicleucel; JNJ-68284528
Online: 3 July 2020 (07:30:57 CEST)
ARTICLE
|
doi:10.20944/preprints201905.0109.v2
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
child; diarrhea; water sanitation and hygiene; rehydration solution; zinc; case management; antibacterial agents; drug utilization; community participation; India
Online: 14 May 2019 (11:46:53 CEST)
REVIEW
|
doi:10.20944/preprints202305.0034.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
organ-on-a-chip; gut-on-a-chip; intestine; in vitro; ex vivo; ADME; oral bioavailability; drug development; microbiome; IBD
Online: 2 May 2023 (01:15:08 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1204.v1
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
uncomplicated malaria; malaria drug resistance; Multiple-First line Treatment; sub-Saharan Africa
Online: 20 March 2024 (11:34:01 CET)
ARTICLE
|
doi:10.20944/preprints202304.0534.v1
Subject:
Medicine And Pharmacology,
Otolaryngology
Keywords:
micro injection molding; 3D printing; rapid tooling; digital light processing; implant; drug delivery system; dexamethasone; anti-inflammatory; TNF-α; biocompatibility; inner ear therapy
Online: 19 April 2023 (03:57:41 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0003.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug repositioning/repurposing; dopamine transporter (DAT); benztropine; tumoroids; signal transducer and activator of transcription (STAT); circulating tumor cells (CTC); three-dimensional (3D) culture
Online: 3 February 2020 (03:16:54 CET)
ARTICLE
|
doi:10.20944/preprints202111.0395.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
Tamarind Gum; Hydrogels; Semi-IPNs; Green synthesis; Silver Nanoparticles; Drug Delivery; Chemotherapeutics; HCT116 Cell; Anti-microbial
Online: 22 November 2021 (13:46:47 CET)
REVIEW
|
doi:10.20944/preprints201910.0144.v6
Subject:
Biology And Life Sciences,
Virology
Keywords:
virus; antiviral drug; drug discovery; drug development; broad-spectrum antivirals
Online: 14 February 2020 (02:27:24 CET)
ARTICLE
|
doi:10.20944/preprints202309.0069.v1
Subject:
Public Health And Healthcare,
Health Policy And Services
Keywords:
MSM; trends; high-risk sexual behaviors; HIV; sexualized drug use; chemsex; sexually transmitted infections
Online: 4 September 2023 (02:43:27 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0650.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
3D printing; hybrid scaffold; poly(caprolactone); chitosan; vancomycin; mesenchymal stem cells; tissue engineering; drug-delivery systems (DDSs); M osteomyelitis
Online: 9 May 2023 (12:05:37 CEST)
CASE REPORT
|
doi:10.20944/preprints202403.1054.v1
Subject:
Medicine And Pharmacology,
Emergency Medicine
Keywords:
cibenzoline succinate; drug toxicity; drug interaction; Extracorporeal Membrane Oxygenation
Online: 18 March 2024 (14:27:39 CET)
ARTICLE
|
doi:10.20944/preprints202402.1726.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
pyrvinium pamoate; pancreatic cancer; drug repurposing; drug combination; gemcitabine
Online: 29 February 2024 (10:49:18 CET)
REVIEW
|
doi:10.20944/preprints202201.0440.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
electrophiles; signaling; profiling; drug mechanism; drug discovery; T-REX
Online: 28 January 2022 (14:57:08 CET)
ARTICLE
|
doi:10.20944/preprints202012.0770.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
BRF2; cancer; molecular dynamics simulation; drug repurposing; drug discovery
Online: 16 July 2021 (11:40:34 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0773.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
oncology drugs; health technology assessment; drug prices; drug access; Canada
Online: 14 February 2024 (05:27:56 CET)
ARTICLE
|
doi:10.20944/preprints202204.0224.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
COVID-19; SARS-CoV-2; drug discovery; multitargeting; computational drug repurposing
Online: 26 April 2022 (03:39:06 CEST)
REVIEW
|
doi:10.20944/preprints202402.0070.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
drug-induced; drug-induced parkinsonism; parkinsonism; dystonia; drug-induced side-effects; tardive syndrome; basal ganglia; dyskinesia; secondary; movement disorder
Online: 1 February 2024 (10:30:01 CET)
ARTICLE
|
doi:10.20944/preprints202310.0922.v1
Online: 16 October 2023 (03:39:25 CEST)
REVIEW
|
doi:10.20944/preprints202307.2100.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Drug; Pleiotropic; Neurodegeneration; Alzheimer
Online: 31 July 2023 (10:41:17 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0523.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
pharmacovigilance; adverse drug reactions; ChatGPT; artificial intelligence; phase 4 studies; drug safety
Online: 8 April 2024 (11:16:12 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0516.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
vaccination; drug allergy; anaphylaxis; rash; side effect; adverse drug reaction; COVID-19
Online: 8 April 2024 (08:28:10 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0316.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Valproic acid; Drug-induced liver injury; Adverse drug reaction; Case-control study
Online: 18 January 2021 (11:11:04 CET)
ARTICLE
|
doi:10.20944/preprints201610.0025.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
drug repurposing; translational bioinformatics; transcriptomics; transcriptome analysis; drug discovery; protocol; gene expression
Online: 9 October 2016 (08:42:23 CEST)
ARTICLE
|
doi:10.20944/preprints202312.2064.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Hypertension, Subcutaneous Implants, Hot Melt Extrusion, Controlled Drug Delivery, Biodegradable, Implantable Drug Delivery
Online: 27 December 2023 (09:45:50 CET)
REVIEW
|
doi:10.20944/preprints201907.0286.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
HIV-1 Gag; Gag inhibitors; Protease; Protease inhibitors; drug resistance mutations; drug design
Online: 25 July 2019 (10:05:03 CEST)
REVIEW
|
doi:10.20944/preprints202403.0327.v1
Online: 6 March 2024 (10:55:34 CET)
REVIEW
|
doi:10.20944/preprints202309.0185.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
BRAF; MEK; tumor; drug resistance
Online: 5 September 2023 (03:53:23 CEST)
REVIEW
|
doi:10.20944/preprints202306.1009.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Antifungal; Drug delivery; Polymers; Nanometer
Online: 14 June 2023 (07:57:36 CEST)
REVIEW
|
doi:10.20944/preprints202210.0270.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
SJS; TEN; Adverse drug reactions
Online: 19 October 2022 (07:28:11 CEST)
REVIEW
|
doi:10.20944/preprints202105.0084.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
peritoneal, HIPEC, intraperitoneal, drug transport
Online: 6 May 2021 (12:58:55 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0327.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Multi-drug resistance; Tuberculosis; Pakistan
Online: 12 November 2020 (08:24:40 CET)
ARTICLE
|
doi:10.20944/preprints201905.0297.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
lignin; drug release; paracetamol; disintegration
Online: 24 May 2019 (12:40:01 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0978.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
drug allergy; rapid drug desensitization; same‐day desensitization; chemotherapy allergy; personalized & precision medicine
Online: 15 April 2024 (14:17:59 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1433.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
FLT3 Inhibitors; Ligand-based Drug Design; Computer-Aided Drug Design; QSAR Modeling; AML Treatment
Online: 25 March 2024 (08:47:40 CET)
REVIEW
|
doi:10.20944/preprints202308.0688.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Urothelial cell cancer; metastasis, drug resistance, immunotherapy; immune checkpoint inhibitors; tumorigenesis; antibody–drug conjugate.
Online: 9 August 2023 (08:23:29 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0222.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
ocular surface disease; dry eye disease; antioxidant; Xanthohumol; drug delivery; drug formulation; PLGA; nanoparticles
Online: 8 April 2021 (09:09:24 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0161.v2
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
COVID-19; docking; drug repurposing; natural products; in silico drug design; viral replication inhibition
Online: 1 June 2020 (02:42:54 CEST)
REVIEW
|
doi:10.20944/preprints201807.0518.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
virus; antiviral agent; drug target; drug side effect; innate immunity; precision medicine; systems biology
Online: 26 July 2018 (15:33:03 CEST)
REVIEW
|
doi:10.20944/preprints202106.0305.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
dietary flavonoids; cardioprotective effects; ROS scavenging; myocardial dysfunction; bioavailability and drug metabolism; toxicity; drug discovery
Online: 11 June 2021 (08:44:01 CEST)
COMMENTARY
|
doi:10.3390/sci2030070
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
small molecule inhibitor; personalized medicine; precision medicine; oncology; targeted therapy; drug delivery; drug screening; chemotherapy
Online: 8 September 2020 (00:00:00 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202004.0043.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
lactation; physiology-based lactation models; drug exposure prediction; fasting; drug safety; newborn; infant; human milk
Online: 6 April 2020 (09:11:05 CEST)
COMMUNICATION
|
doi:10.20944/preprints202002.0418.v2
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
virtual screening; molecular docking; drug repurposing; drug repositioning; anti-viral drugs; Coronavirus; COVID-19; 2019-nCoV; SARS-CoV-2
Online: 9 March 2020 (02:29:04 CET)
REVIEW
|
doi:10.20944/preprints202405.0818.v1
Subject:
Biology And Biotechnology,
Biology And Life Sciences
Keywords:
drug, paracetamol; Human body; Excess use
Online: 13 May 2024 (10:38:23 CEST)
REVIEW
|
doi:10.20944/preprints202404.1060.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
mRNA, vaccine development, drug development, regulation
Online: 16 April 2024 (13:56:02 CEST)