Bachani, P.; Kumar, L.; Kumar, N.; Shaukat, F. Prevalence of Multidrug Resistance Tuberculosis. Preprints2020, 2020110327. https://doi.org/10.20944/preprints202011.0327.v1
APA Style
Bachani, P., Kumar, L., Kumar, N., & Shaukat, F. (2020). Prevalence of Multidrug Resistance Tuberculosis. Preprints. https://doi.org/10.20944/preprints202011.0327.v1
Chicago/Turabian Style
Bachani, P., Naresh Kumar and Faizan Shaukat. 2020 "Prevalence of Multidrug Resistance Tuberculosis" Preprints. https://doi.org/10.20944/preprints202011.0327.v1
Abstract
Introduction Tuberculosis is common in Pakistan. Due to various factors including socioeconomic factors, compliance is poor to anti-tuberculosis drugs, leading to resistance. We aim to determine the prevalence of Multidrug resistance (MDR) tuberculosis in Pakistani population.Methods A prospective observational study was conducted from April 1, 2019, to December 31, 2019, in the Pulmonology department of a tertiary care hospital in Pakistan. Culture and sensitivity were assessed using a sputum sample or, in cases of an absent sputum sample, from Broncho alveolar lavage.ResultsApproximately 71.3% percent patients who had tuberculosis were found to be resistant to Isoniazid and around 48.6% did not respond to Rifampin. Multi-drug resistant was found in 29.4% participants.ConclusionMulti-drug resistance tuberculosis is very prevalent in Pakistan, which may increase burden on health care system and may lead to various complications of tuberculosis.
Keywords
Multi-drug resistance; Tuberculosis; Pakistan
Subject
Medicine and Pharmacology, Epidemiology and Infectious Diseases
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
