Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Unveiling Medication-Related Osteonecrosis of the Jaw: A Narrative Review of Etiology, Drug Holidays, and Treatment Strategies

Version 1 : Received: 2 February 2024 / Approved: 2 February 2024 / Online: 2 February 2024 (11:48:46 CET)

How to cite: Oh, J.; Kim, S. Unveiling Medication-Related Osteonecrosis of the Jaw: A Narrative Review of Etiology, Drug Holidays, and Treatment Strategies. Preprints 2024, 2024020148. https://doi.org/10.20944/preprints202402.0148.v1 Oh, J.; Kim, S. Unveiling Medication-Related Osteonecrosis of the Jaw: A Narrative Review of Etiology, Drug Holidays, and Treatment Strategies. Preprints 2024, 2024020148. https://doi.org/10.20944/preprints202402.0148.v1

Abstract

This narrative review provides a thorough examination of medication-related osteonecrosis of the jaw (MRONJ), encompassing its etiology, the role of drug holidays, and contemporary treatment approaches. By systematically analyzing literature from 2022 to 2023, this paper synthesizes the latest findings and trends in MRONJ research. The study emphasizes the importance of a holistic understanding of MRONJ, beginning with its etiological factors, assessing the therapeutic implications of drug holidays, and evaluating the efficacy of current treatment modalities. This review aims to offer clinicians and researchers a consolidated resource, highlighting the intricacies of MRONJ management and proposing directions for future research. Through this comprehensive approach, the paper seeks to advance the understanding and treatment of MRONJ, ensuring an evidence-based, patient-centric approach in clinical practice.

Keywords

medication-related osteonecrosis of the jaw; drug holiday; treatment; tooth extraction; incidence

Subject

Medicine and Pharmacology, Dentistry and Oral Surgery

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