Keywords: Vascular Malformation, Diode Laser, Angioma, Blue light, Conservative

Many cities are increasingly adopting blue-green infrastructure (BGI) to bolster resilience against environmental challenges. Beyond its well-acknowledged environmental benefits, the role of BGI in enhancing social resilience is becoming an equally important area of focus. However, the integration of BGI to foster social resilience presents complexities, stemming from the evolving and occasionally ambiguous definition of social resilience. Considering the broad application of BGI across various disciplines makes the evaluation of social resilience within a BGI framework complex. Consequently, a structured approach to develop a clear framework tailored to understanding and measuring social resilience in a BGI setting is needed. This study consolidates various existing frameworks of social resilience, especially utilizing the detailed 5S framework proposed by Saja et al. [1]. It integrates findings from an extensive review of literature on social resilience to develop a novel conceptual framework, the BGI Social Resilience Framework. This new framework specifically aims to capture the distinct social aspects and advantages associated with BGI. The BGI Social Resilience Framework is organized into a three-tier model focusing on four critical aspects of social resilience—social values, social capital, social structure, and social equity—and explores how these aspects are interconnected. Characteristics and indicators are customized to accomodate the BGI context in a way that integrates the physical and human dimensions within a comprehensive approach to measurement that uses a combination of qualitative and quantitative methods. Specifically, this research formulates a theoretical framework for BGI with the aim of investigating BGI strategies and viewpoints that bolster social resilience. The BGI Social Resilience Framework takes into account the varied demographics and the physical characteristics of urban areas to explore ways to create BGI spaces that are more inclusive and contribute to the enhancement of social resilience.

Grating (moiré) interferometry is one of the well-known methods for full-field in-plane displacement and strain measurement. There are many design solutions for grating interferometers, including systems with a microinterferometric waveguide head. This article proposes a modification to the conventional waveguide interferometer head, enabling the implementation of a polarization fringe phase shift for automatic fringe pattern analysis. The article presents both the theoretical consideration of the proposed solution and its experimental verification, along with the concept of the in-plane displacement/strain sensor using the described head.

Eelgrass meadows have attracted a lot of attention not only for their ability to maintain marine ecosystems as feeding grounds for marine organisms, but also for their potential to store atmos-pheric and dissolved CO2 as blue carbon. This study comprehensively evaluated the bacterial and chemical composition data obtained from eelgrass sediments of different scales along the coast of Japan to investigate the sediment effect on the acclimatization of eelgrass. Regardless eelgrass habitat, approximately 1% Anaerolineales, Babeliales, Cytophagales, and Phycisphaerales were present in the bottom sediment. Sulfate-reducing bacteria (SRB) were present at 3.69 % in eelgrass sediment compared to 1.70 % in bare sediment. Sulfur-oxidizing bacteria (SOB) were present at 2.81% and 1.10% in the eelgrass and bare sediment, respectively. Bacterial composition analysis and linear discriminant analysis revealed that sulfur-oxidizing bacteria detoxified H2S in the eelgrass meadows and that the larger-scale eelgrass meadows had a higher diversity of sul-fur-oxidizing bacteria. Our result indicated that one of the following systems detoxifies the H2S in eelgrass meadows microbial oxidation by sulfur-oxidizing bacteria, oxidation by O2 perme-ated by the physical diffusion of benthos. This study indicated the issues of maintaining sustain-able conservation of the eelgrass bed.

Myanmar is located in the Indo-Burma biodiversity hotspot, but lacks understanding of the bio-diversity hotspots and protected areas within its borders. Climate change affects the effective-ness of protected areas and the potential distribution range of species. Based on Myanmar's re-gional characteristics, endangered status, and representativeness, this paper selects species and identifies biodiversity hotspots using the MaxEnt model. We studied the biodiversity within the terrestrial protected area network in Myanmar, as well as the potential for cross-boundary range shifts among protected areas under different climate scenarios. Species populations outside My-anmar's protected area network may not be able to find suitable habitats in the future, further exacerbating climate-related extinction risks. Additionally, some protected areas in Myanmar may not be fully utilizing their biodiversity representation potential, and with scientific spatial planning, Myanmar's protected areas could support a large number of species. In the context of continued warming, identifying new protected areas that encompass the future and current climatic niches of protected areas can increase the capacity for sustained biodiversity conservation. We hope that this study provides insights for increasing the effectiveness of Myanmar's protect-ed area network and emphasizes the urgency of coordinated protection of protected areas and biodiversity hotspots.

Cutaneous mycoses are common infections whose treatment has become more complex due to increasing antifungal resistance and the need for prolonged therapies, hindering patient adher-ence and increasing the incidence of adverse effects. Consequently, the use of physical therapies, especially photodynamic therapy (PDT), has increased for the treatment of onychomycosis due to its antimicrobial capacity mediated by the production of reactive oxygen species. This study investigates the in vitro effect of the combination of blue light (448 nm) and red light (645 nm) with terbinafine on the cell viability of human keratinocytes and the production of reactive ox-ygen species. The combination of terbinafine and blue light exhibits a synergistic effect on the production of reactive oxygen species and a significant increase in the expression of superoxide dismutase (SOD), an enzyme involved in the reduction of superoxide ions (O2-) and the genera-tion of hydrogen peroxide (H2O2). Such effect could be useful in clinical practice to improve the response of cutaneous mycoses to pharmacological treatment, reduce their toxicity, and shorten their duration.

Despite the extensive literature on missing data theory and cautionary articles emphasizing the importance of realistic analysis for healthcare data, a critical gap persists in incorporating domain knowledge into missing data problem formulation, assumption specification, and method development. In this paper, we highlight the gap particularly for observational data from healthcare facilities. We address this gap by identifying ten fundamental missingness scenarios arising during data measurement, recording, and pre-processing in observational health data, influenced by physicians, patients, healthcare facilities, and data scientists. We analyze the effect of scenarios on estimand formulation, missing data identification, estimation, and sensitivity analysis. To emphasize how domain-informed analysis can improve method reliability, we conduct simulation studies under the influence of various missingness scenarios. We compare the results of three common methods in medical data analysis (complete-case analysis, Missforest imputation, and inverse probability weighting estimation) for two estimands (variable mean estimation and classification accuracy). We advocate for our analysis approach as a reference for the analysis of observational health data. Furthermore, we posit that the proposed analysis framework is applicable to other medical domains, including medical wearable data analysis.

We demonstrate how a rigorous mathematical approach can be used to extract a current CMB temperature of 2.7276 ±0.0723 K from the 580 type Ia supernova data points in the Union2 database. Using redshift formula: z = Sqrt(Rh/R_t) − 1, incorporated into our new CMB redshift prediction redshift formula, we find that the above current CMB temperature value is a remarkably good match for this particular data set. In addition, we can alternatively start out with the measured current CMB temperature and extract the Hubble constant from all 580 supernovae. We then get an estimated Hubble constant of H0 = 66.8711+0.0019 km/s/Mpc when using the CMB temperature from the recent Dhal et al study [1] in combination with redshifts from all 580 supernovae. Furthermore, we get an estimated Hubble constant value of H_0 = 66.8943+0.0287 km/s/Mpc when using the CMB temperature measured by Fixsen [2]. In summary, our simple model essentially perfectly matches all 580 type Ia supernova redshifts while extracting H_0 or T_0 values. The Hubble constant we extract by this method fits very well with the Hubble constant extracted from the CMB by other studies. We believe that our new approach likely solves the Hubble tension problem, at least inside R_h = ct cosmology.

The SBA-15 loaded with methylene blue was successfully prepared by sample adsorption of methylene blue in SBA-15 and is characterized by an XRD, SEM, FTIR, and BET. The photocatalytic activity for methyl orange (MO) degradation was investigated under visible light irradiation under LEDs. Experimental results demonstrate that the SBA-15-MB exhibited higher photocatalytic activity than SBA-15 under visible light irradiation. The degradation efficiency of MO (50 ppm) by SBA-15-MB could reach 80% within 180 min under 25W LED visible light. The photocatalytic activity of SBA-15 could be attributed to the excitation of methylene blue by visible light, the transfer of electrons from methylene blue to SBA-15, and the production of radicals at the surface of SBA-15.

Transition metal complexes have historically played a pivotal role in creating vibrant pigments utilized across artistic mediums such as ceramics, paintings, and glass mosaics. Despite their extensive historical use, our understanding of the mechanisms governing transition metal complex behavior has predominantly emerged in recent times, leaving numerous aspects of this process ripe for exploration. These complexes exhibit striking color variations under diverse conditions when employed in pigment formulations. This review utilizes a bottom-up scientific approach, spanning from microscopic to macroscopic scales, to unravel the molecular origins of the colors generated by transition metal complexes in pigments and ceramic glazes. Advanced spectroscopy techniques and computational chemistry play pivotal roles in this endeavor, highlighting the significance of understanding and utilizing analytical data effectively, with careful consideration of each technique's specific application. Furthermore, the review investigates the influence of processing conditions on color variations, providing valuable insights for artists and manufacturers aiming to enhance the precision and quality of their creations while mitigating environmental impact.

Abstract: Experiments conducted to date to verify the relativistic gravitational time dilation have limited scientific significance because the basic postulate of Einstein’s relativistic GR that the same time (t0) is measured in all non-inertial frames of reference, because all non-inertial frames of reference must be equal, has not yet been verified by time measurements. According to Einstein's relativistic GR, a correlation between time and different gravitational potentials must be the result of a relative relation between non-inertial frames of reference and must not the result of any other physical influence. An experiment that can differentiate between a causal correlation (relative relation) and an apparent correlation (relativistic relation) between time and gravitational potentials is still outstanding. The expressions "relative" and "relativistic" are often used as synonyms. However, Einstein's GR is a relativistic theory. In the case of general relativity, relativistic means that time depends only on the relative relation between non-inertial frames of reference and not on other physical factors. The author proposes an easy-to-realize experiment that is able to distinguish between a causal correlation (relative relation) and an apparent correlation (relativistic relation) between time and gravitational potentials, which can confirm or falsify Einstein's relativistic GR. .

The expression of polysialic acid (polySia) on the neuronal cell adhesion molecule (NCAM), is called NCAM-polysialylation, which is strongly related to the migration and invasion of tumor cells and with aggressive in the clinic. Thus, it’s important to select a proper drug to block tumor cell migration for clinic treatment. In this study, we proposed that lactoferrin (LFcinB11) may be a more ideal candidate for inhibition of NCAM polysialylation comparing with CMP and low molecular weight heparin (LMWH), which were determined based on our NMR studies. On the other hand, because neutrophil extracellular traps (NET) is the most dramatic stage in cell death process, and NETs’ release are related to pathogenesis of autoimmune and inflammatory disorders, with proposed involvement in glomerulonephritis, chronic lung disease, sepsis and vascular disorders. In this study, the molecular mechanism of inhibition of NETs’ release using LFcinB11 as inhibitor was also determined. Based on these results, LFcinB11 is proposed to be bifunctional inhibitor for inhibiting both NCAM polysialylation and NETs releases.

Abstracts In this article, we describe a simple procedure for evaluating the sterility of nutrient media using a shear-horizontal surface acoustic wave (SH-SAW) biosensor. We used the SH-SAW biosensor platform to monitor the time-dependent phase responses of the material for the media that binds to a monolayer of 3-mercaptopropanyl-N-hydroxy succinimide on the biosensor surface. Increases in the phase shift less than 50% of the starting phase shift recorded 180 minutes after the sterilization indicate a successful sterility test of the media. Our devices were then applied to sterility testing using a viable Escherichia coli (E. coli) K-12 solution to confirm our hypothesis. Filtered LB Broth was the negative control, and a 24-hour culture of E. coli was the positive control. Before testing, the cell solution was pelleted, the media decanted, and then replaced with a 1x phosphate-buffered saline solution (1x PBS). Since we know that the N-hydroxysuccinimide residues will bind to amine groups, only in cases where microbial species are present will the surface binding increase greater than 50%. We confirmed our hypothesis using SH-SAW biosensors and overnight E. coli cultures. The sensitivity for our 250 MHz quartz SH-SAW sensors was calculated based on the response from the E. coli K-12 solution over the linear dynamic range, which appears to be 2x10^4 – 2x10^7 CFU per ml and has a sensitivity of S = 1.655x10^5 o m2 Kg-1. The limit of detection (LOD) for these sensors was calculated to be approximately 2x10^-9 grams (g), which is estimated to be approximately 2,000 Escherichia coli (E. coli) K-12 cells. However, the sensitivity and insertion loss remained approximately unchanged before and after coating the sensor with 3,3'-Dithiobis(succinimidyl) Propionate (DSP).

Seaweed farming has been growing in prominence in the coastal region of Kwale County, Kenya, as a livelihood led by women since the turn of the century, however the sector remains far below its full productive capacity. As such, this study explores the factors that influence women’s ability to access seaweed farming through engagements with the theories of intersectionality. The Blue Empowerment Project is seeking to upscale seaweed farming in this region to promote women’s empowerment and this study questions the extent to which men should be included in such an endeavour. It finds that several factors may intersect with gender to create varying levels of (dis)advantage amongst women in this region, and that we may need to reframe the conceptualisation of women’s empowerment to be inclusive of men. This study therefore makes a range of recommendations for the BEP, development practitioners in general, and researchers to inform them of how women’s empowerment initiatives may be made more inclusive and transformational.

The aging mechanism of 10% and 30% nickel substituted manganese hexacyanoferrate cathode material in aqueous zinc-ion batteries has been explored through the advanced synchrotron-based two-dimensional x-ray fluorescence technique. Thanks to the two-dimension modality, not only the metal concentration dynamics throughout the entire electrodes was followed during the aging process, but their spatial distribution was also revealed, suggesting the route of the material transformation. The dissolution of Mn and Ni, and the penetration of Zn inside the framework, alongside the Mn aggregations outside the hexacyanoferrate framework were detected. Additionally, the possibility of conducting x-ray absorption spectroscopy measurements on the regions of interest made it possible to explore the chemical state of each metal, and furthermore, synchrotron-based powder x-ray diffraction demonstrated the gradual structural modification in 30% Ni-containing sample series, in terms of the different phase formation.

Polymer inclusion membranes (PIMs), which contained cellulose tri-acetate used as a polymer base, a plasticizer in the form of o-NPOE, and meso-tetra methyl tetrakis-[methyl-2-(4-acetlphenoxy)] calix[4]pyrrole (KP) used as a carrier, were prepared and tested for the effective purification of aqueous solutions of methylene blue dye. The scanning electron microscope (SEM), thermogravimetric analysis (TGA), and attenuated total reflection Fourier transform infrared (ATR-FTIR) were used to define the microstructure and surface of PIMs. Experimental results showed that with the increased concentration of methylene blue in an aqueous solution, the removal percentage also increased. Further observation also showed that the flux increased with the rise of the source phase pH values from 3 to 10. The carrier and plasticizer content in the membrane significantly influenced the membrane’s transport properties. The optimal composition of the membrane in per cent by weight was for KP: 74% plasticizer; 18% support; 8% carrier. It was shown that the membrane with optimal composition showed good reusability and enabled the easy and spontaneous separation of methylene blue from aqueous solutions.

This paper discusses how Marsascala, a coastal town in Malta, has been urbanized over the years, with particular attention to the development of the tourist industry. In this regard, Bruce Young’s (1983) “general model of the process of ‘touristization’ and landscape change” is engaged with in conjunction with other conceptualisations of tourism and urban development. This paper contributes to the following sustainable development goals respectively, 3 (Good Health and Wellbeing); 8 (Decent Work and Economic Growth); 11 (Sustainable Cities and Communities); 14 (Life Below Water); and 15 (Life on Land), in particular with respect to quality of life, urbanization and respective social, environmental, and economic impacts, and through respective recommendations for a sustainable tourism in Marsascala and similar localities.

The analysis of the current safety standards for electric toys showed that the normative intensity limits for visible light emitted by LEDs integrated in toys are overestimated. These limits were originally set in a scientific article published in 2012 that was adapted into the international safety standard published in 2017, and into the subsequent European and national standards, all published in 2020. The overestimation of the intensity limits results from several errors made in the original article. Accordingly, the current normative intensity limits for visible light used in toys do not protect the children’s eyes against adverse effects of exposure to high intensity LEDs which may compromise their visual health. Updating the safety standards for electric toys using a method based on robust scientific data is recommended to protect children's visual health and ensure their long-term well-being.

Urban rivers and waterfronts play a vital role in the ecological, social, and economic fabric of cities, providing not only aesthetic value but also serving as important ecosystems that contribute to the overall well-being of urban environments. However, many urban rivers, including the Beirut River in Lebanon, face challenges such as pollution, neglect, and the loss of recreational and ecological value due to urbanization and industrialization. According to the Lebanese MOE (Ministry of Environment), almost 70% of Lebanese rivers are polluted due to untreated waste management systems and which leads to undrinkable water and possible flooding disasters if not treated. This study addresses the problem of abandoned and degraded spaces along the Beirut River riverside through the application of urban acupuncture, a strategic approach that targets specific points in the urban environment to stimulate positive change and regeneration. The aim of the study is to assess the effectiveness of implementing small-scale ‘sensitive urban points’ known as urban acupuncture as the method for regenerating the Beirut River riverside, with the hypothesis that targeted interventions through Blue Urban Acupuncture or Aqua-puncture- can lead to significant improvements in the ecological, social, and economic aspects of the area that re-connect the people of Beirut with its river. The methodology involves a multidisciplinary approach that integrates urban design, and community engagement, and analysing similar examples of different approaches through creating a comparative table. Data collection includes environmental assessments of water quality, biodiversity, and ecosystem health, as well as social surveys to understand community needs and perceptions. By applying urban acupuncture principles to the Beirut River riverside, this study seeks to demonstrate how strategic interventions can lead to the regeneration of abandoned spaces, improve the overall quality of the urban environment, and create sustainable and inclusive riverside landscapes that benefit both the environment and the community.

We introduce a series of twisted donor-acceptor (D-A) carbazole-benzophenone based electroactive bipolar derivatives that were synthesized through the reaction of 4-fluorobenzophenone with various partially alkylated 3,3’-bicarbazoles. The comprehensive structural characterization of these compounds is provided. These amorphous materials exhibit suitable glass transition temperatures ranging from 57 to 102 °C and demonstrate high thermal stability, with decomposition temperatures reaching 400 °C. Moreover, the developed materials exhibit elevated photoluminescence quantum yields (PLQY) of up to 75.5% and favorable HOMO-LUMO levels, along with suitable triplet-singlet state energy values. Due to their good solubility and suitable film-forming properties, all the compounds were evaluated as blue emitters dispersed in 4,4’-bis(N-carbazolyl)-1,10-biphenyl (CBP) host for the fabrication of organic light-emitting diodes (OLEDs) in concentration dependent experiments. Among these experiments, the device containing 15 wt% of the guest 4-(9’-{2-ethylhexyl}-[3,3’]-bicarbazol-9-yl)benzophenone demonstrated the best characteristics, achieving maximum brightness of 3581 cd/m2, current efficiency of 5.7 cd/A, power efficiency of 4.1 lm/W and external quantum efficiency of 2.7%.

ACL instability poses a significant challenge in traumatology and orthopedic medicine, often requiring accurate diagnosis for appropriate treatment. While the pivot-shift test offers a crucial means of assessment, its reliance on subjective interpretation underscores the need for supplementary imaging studies. This study aims to address this limitation by developing a Bayesian classification algorithm tailored for integration into a mobile application. Using the built-in inertial sensors of smartphones, this new approach aims to dynamically evaluate rotational stability during knee examinations. Orthopedic specialists conducted knee evaluations on 52 subjects, with subsequent analysis revealing interesting insights. Intraobserver and interobserver analyses, as measured by ICC, demonstrated strong agreement both in terms of timing between maneuvers (ICC = 0.94) and signal amplitude (ICC = 0.71-0.66). Notably, the Bayesian algorithm successfully classified 95% of joint hypermobility cases, with an additional 7 cases of hyperlaxity identified by the Pivot-Shift Meter (PSM). These findings highlight the practicality and effectiveness of implementing a Bayesian classification algorithm within a mobile application for assessing and categorizing signals captured by smartphone inertial sensors during the pivot-shift test.

It has been theorized that black holes are surrounded by firewalls, although there is not universal agreement concerning this. We first review basic concepts pertaining to Schwarzschild black holes and Hawking radiation. Then we discuss the anticipation of Hawking radiation—albeit from non-black holes—initially by R. C. Tolman and shortly thereafter with P. Ehrenfest. We compare evaporation into a vacuum at absolute zero (0 K) of black holes with that of non-black holes, and show that not only black holes but also non-black holes evaporate within a finite time. The times required for evaporation of black holes and non-black holes are compared. Next, we show that (i) if firewalls exist, they can originate via Hawking radiation at the minimum possible ruler distance (the Planck length) beyond the Schwarzschild horizon, where it has not suffered any gravitational redshift, or, alternatively, suffered maximal gravitational blueshift and (ii) the firewall temperature is on the order of the Planck temperature, independently of the mass and hence also of the Schwarzschild radius of a Schwarzschild black hole. We then explain the exponential nature of the gravitational frequency shift as a function of the gravitational potential. Next, we consider the firewall-mass problem, and provide an at least prima facie tentative resolution thereto based on: (i) the mass of a firewall being canceled by the negative gravitational mass = (negative gravitational energy)/c² accompanying its formation, (ii) the unchanged observations of a distant observer upon formation of a firewall, and (iii) Birkhoff's Theorem (actually first discovered by Jørg Tofte Jebsen). We then consider one aspect of thermodynamics in gravitational fields, showing that equilibrium relativistic gravitational temperature gradients cannot be exploited to violate the Second Law of Thermodynamics.

Our environment has been impacted by man-made pollutants mainly industries make substantial use of synthetic dyes which exhibit cytotoxicity and have significant environmental consequences. Effective photocatalyst-based approaches for degrading synthetic dyes into less toxic chemical are of great interest. Synthesizing NPs using biological approaches, particularly plant-based approaches offer advantages, decreasing the risk of NPs losing biocompatibility during synthesis, cost-effectiveness, and eco-friendliness. In this study, we employed a green synthesis method to produce manganese oxide nanoparticles (MnO NPs) utilizing leaf extract from the Lathyrus Aphaca plant. The synthesized MnOx NPs were characterized through various techniques; X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), Fourier-transform infrared spectroscopy (FTIR), and UV–visible spectroscopy. XRD analysis showed distinct peaks, indicated the presence crystallographic planes within the MnO₂ nanoparticles, thus confirming their crystalline structure. SEM study highlighted closely packed configurations with average size of approximately ≥ 50-70 nm, with well-defined boundaries. EDX analysis showed the presence of elemental manganese (Mn) in the samples, with peaks corresponding to Mn detected at lower energy levels, predominantly represented by MnO. FTIR, showed the presence of the O-O stretching mode at a frequency of 719 cm^-1, the presence of MnO₆ oxides of manganese, and peak at 548 cm^-1 corresponded to the Mn-O stretching mode. Furthermore, the green-synthesized manganese oxide nanoparticles exhibited promising photocatalytic and adsorption capabilities against Methylene Blue (MB) dye, leading to approximately 93.21% degradation of MB when treated with the green-synthesized MnO nanoparticles derived from plant extract. This highlights the efficacy and potential of these nanoparticles in environmental remediation applications, particularly in the degradation of methylene blue contaminants.

This article discusses how, in today’s world of disruptive and dramatic social change (DSC), non-sports related coaching, which includes a wide range of services such as life coaching, career coaching, executive coaching, and team coaching, can inadvertently fuel undesirable social dynamics. There is little or no awareness of this risk among coaches and coachees. The global, fast-growing, multi-billion-dollar industry aimed at supporting people and organisations to perform better and increase wellbeing while managing and adapting to change has been developed with limited sociological input. The article is based on 15 years of social constructionist-informed reflective practice by a sociologist-turned-coach, and uses a multi-layered autoethnographic account to argue for a sociologically informed paradigm shift in coaching, as well as relevant sociological knowledge and social and human sciences research methodology in coaches’ education. It presents the rationale and key features of a new coaching approach that places DSC-relevant sociological concepts at the heart of the coaching process, helps people develop psycho-sociological awareness, and uses a learning-to-develop through research design. A new definition of coaching to address DSC is derived. Coaching practitioners will find DSC-relevant sociological concepts, critical reflections, coaching questions, and procedures to expand coaching effectiveness. Interdisciplinary research topics combining coaching sociology and coaching psychology are suggested.

Access to urban green and blue spaces (UGBS) has been associated with positive effects on health and wellbeing; however, the past decades have seen a decline in quality and user satisfaction with UGBS. This reflects the mounting challenges that many UK cities face in providing appropriate public facilities alongside issues such as health inequalities, an ageing population, climate change, and loss of biodiversity. At present, little is known about the preferences of different population subgroups and, specifically, the UGBS they visit and the spaces they avoid. Using a public participatory geographic information system (PPGIS), the overall aim of the research presented here was to investigate the preferences of different population subgroups in urban areas, and the UGBS they visit, using Edinburgh, Scotland as a case study. We created a baseline visitor demographic profile for UGBS use, and highlighted how visitors perceive, physically access, use, and engage with UGBS. The results revealed considerable variation in UGBS preference: one person’s favourite UGBS may be one that someone else dislikes and avoids. It is clear that adapting UGBS to suit local communities should not be a ‘one-size-fits-all’ approach. The conflicting views and preferences of different groups of respondents point to the importance of developing policies and park management plans that can accommodate a variety of uses and experiential qualities within individual parks. PPGIS offers an ideal tool for achieving this

Abstract: Laryngoscopy for tracheal intubation has been developed for many decades. Among various conventional laryngoscopes, videolaryngoscopes (VL) have been applied in different patient populations, including difficult airways. The safety and effectiveness of VL have been repeatedly studied in both normal and difficult airways. The superiority of VL then has been observed and is advocated as the standard of care. In contrast to laryngoscopy, the development of video-assisted intubating stylet (VS, also named as styletubation) has been noticed two dec-ades ago. Since then, sporadic clinical experiences of use have appeared in literature. In this re-view article, we presented our vast use experiences of the styletubation (more than 55,000 pa-tients since 2016). We found this technique is swift (the time to intubate: from 3 s to 10 s), smooth (first-attempt success rate: 100%), safe (no airway complications), and easy (high subjective satis-faction and fast learning curve for the novice trainees) in both normal and difficult airway sce-narios. We therefore propose styletubation technique can be feasibly applied as universal rou-tine use for tracheal intubation.

Nanocomposites of TiO₂ Degussa P25 nanoparticles/activated carbon (TiO₂/AC ) were prepared at various mass ratios of (4:1), (3:2), (2:3), and (1:4) by a facile process. The effects of TiO₂/AC mass ratios on the structural, morphological, and photocatalytic properties were systematically studied in comparison with bare TiO₂ and bare AC. TiO₂ nanoparticles exhibited dominant anatase and minor rutile phases, and a crystallite size of approximately 21 nm; while AC had XRD peaks of graphite and carbon, and a crystallite size of 49 nm. The composites exhibited tight decoration of TiO₂ nanoparticles on micron-/submicron AC particles, and uniform TiO₂/AC composites were obtained as evidenced by the uniform distribution of Ti, O, and C in an EDS mapping. Moreover, Raman spectra show the typical vibration modes of anatase TiO₂ (e.g., E_1g⁽¹⁾, B_1g⁽¹⁾, E_g⁽³⁾) and carbon materials with D and G bands. The TiO₂/AC with (4:1), (3:2), and (2:3) possessed higher reaction rate constants (k) in photocatalytic degradation of methylene blue (MB) than that of either TiO₂ or AC. Among the investigated materials, TiO₂/AC = 4:1 achieved the highest photocatalytic activity with a high k of 55.2×10^-3 min^-1 and an MB removal efficiency of 96.6% after 30 min treatment under UV-Vis irradiation (120 mW/cm²). The enhanced photocatalytic activity for TiO₂/AC is due to the synergistic effect of the high adsorption capability of AC and the high photocatalytic activity of TiO₂. Furthermore, TiO₂/AC promotes the separation of photoexcited electron/hole (e^-/h⁺) pairs to reduce their recombination rate and thus enhance photocatalytic activity. The optimal TiO₂/AC composite in this study can be used for treating industrial or household wastewater with organic pollutants.

This research challenges the traditional perspective on consumer behavior, which focuses on external factors shaping the sequential stages of decision-making. Instead, it proposes a paradigm shift by treating the decision-making process itself as an independent variable, exploring its impact on various outcomes like purchasing behavior, brand loyalty, and post-purchase satisfaction. This novel approach offers deeper insights into the intricacies of consumer behavior, particularly in the digital age. By uncovering the reciprocal relationships between the decision-making process and other variables, the research provides a more nuanced understanding of how consumers navigate today's complex landscape. It further delves into how variations in the decision-making process across diverse consumer groups influence various outcomes, recognizing the unique characteristics and needs of different demographics. The research also acknowledges the interplay of psychological, social, and contextual factors that shape both the decision-making process and its downstream effects, offering a comprehensive understanding of the multifaceted influences on consumer behavior. Ultimately, by studying the decision-making process as an independent variable, this research aims to equip businesses and researchers with valuable insights, enabling them to better navigate the ever-evolving world of consumer behavior.

This article addresses the urbanization model in valley bottom areas in the city of São Paulo, an-alyzed in its urban planning and socio-environmental aspects, and examines the hydrological impacts triggered by its implementation. It argues that sustainable occupation of urbanized hy-drographic basins should be based on environmental criteria in order to attain a sustainable water management regime that can ensure urban and environmental resilience. In the “Introduction,” the article emphasizes that urbanization in São Paulo has neglected the natural features of river basins, promoting the channeling of watercourses, which resulted in floods and inundations. “Theoretical Basics” brings in key concepts related to the environmental approach of drainage infrastructure with gray and green-blue systems. “Methods” details our qualitative research, bibliographical analyzes, referential case studies, and cartographical analyzes (geoprocessing), focusing on a case study in the Jaguaré creek basin. “Results” includes guidelines and recom-mendations for an urbanization model adjusted to valley bottom areas, applicable to new patterns of urban occupation or to the adjustment of existing patterns. “Discussion” explores the concept of “local sustainable self-development,” and “Conclusions” highlights the importance of an inte-grated, multisectoral, and sustainable planning, adjusted to the characteristics of river basins in valley bottom areas, promoting a socially responsible urban occupation, especially in the face of climate change.

In this paper, the concept of absolute airspace is further elaborated, and the time transform effect, the frequency transform relation of clock timing, and the principle of Doppler effect of special relativistic light are analyzed and demonstrated. Based on the concept of absolute airspace, a new and accurate Doppler effect relation of light (electromagnetic wave) is proposed. It is proved that there is a synchronous relationship between the time shift effect and the frequency change of the timing inside the clock. When the light (electromagnetic wave) source is in motion, the Doppler effect includes two physical mechanisms: the frequency change caused by time transformation effect and the frequency change caused by relative motion. When the light source is in motion, the Doppler effect of the light there are some differences in different directions due to the rotation of the earth. The relation of Doppler effect of special relativistic light is only a highly approximate relation, and its theoretical basis, special relativity, is flawed in principle.

Avian Influenza viruses (AIVs) has posed a significant pandemic threat since their discovery. This review mainly focuses on the epidemiology, virology, and pathogenesis, and treatments of avian influenza viruses. We delve into the global spread, past pandemics, clinical symptoms, severity, and immune response related to AIVs. The review also discusses various control measures, including antiviral drugs, vaccines, and potential future directions in influenza treatment and prevention. Lastly, by summarizing the insights from the previous pandemic control, this review aims to direct effective strategies for managing future influenza pandemics.

The purpose of the research is to investigate the unique solvability of a nonlocal boundary value problem for a loaded equation of parabolic-hyperbolic type in a special domain. Methods: Using representations of a general regular solution, the existence and uniqueness of the problem posed is proved. Results: A new method for proving the unique solvability of nonlocal boundary value problems for one loaded equation of mixed type in a special domain has been formed and developed. Conclusions: The obtained results make it possible to solve some problems of genetics, immunology, transonic gas dynamics and thermal physics, which are associated with displacement.

In this work, we report the engineering of a sub-70 nm nanocomposite of ZnO/Zn2TiO4 using a low-temperature solution-phase method. Titanium isopropoxide and zinc acetate were used as precursors, and isopropyl alcohol and water were used as solvents. The investigation focused on the growth of nanocomposites by varying the concentrations of precursors and surfactants, as well as their efficiency within different pH ranges. All three ZnO/Zn2TiO4 nanocomposites consist of hexagonal wurtzite ZnO and Zn2TiO4 structures in the three nanocomposites. The crystallite size in three ZnO/Zn2TiO4 nanocomposites, with a hexagonal wurtzite ZnO structure, were measured to be 62.67, 40.34, and 39.50 nm. The crystallite size values in three ZnO/Zn2TiO4 nanocomposites were 26.15 nm, 25.36 nm, and 21.24 nm, respectively, with Zn2TiO4. Morphological observations, conducted using FESEM, reveal the formation of three ZnO/Zn2TiO4 nanocomposites across the entire sample. These nanocomposites resemble dispersed cotton packets, with sizes ranging from 18 to 350 nm. Peaks in the range of 610-1250cm-1 are attributed to Ti-O bond formation and peak located at 1350-1450 cm-1 are attributed to Zn-O bond formation. Also, EDX spectrum reveals peaks for various sample components such as Ti, O and Zn. UV spectrums confirmed the formation of three nanocomposite of ZnO/Zn2TiO4 as showing two peaks for each sample. Photocatalytic investigation carried out by analyzing the UV-Visible absorption spectra of methylene blue dye on the surface of ZnO/Zn2TiO4 nanocomposites, dye degradation at various irradiation time intervals, dye degradation at varied catalyst concentrations and the influence of pH on dye-degradation. Furthermore, the said nanocomposites were used to degrade environmental pollutant (Methylene blue dye). Different sets of experiments were conducted under ambient conditions which show an excellent photo catalytic degradation efficiency.

As yin and yang, cancer and diabetes are metabolic disorders characterized by deregulated, yet opposing, metabolic alterations. These metabolic shifts reflect a complex network of defective underlying signaling pathways, which ultimately orchestrate both disease pathogenesis and progression. The Warburg effect portrays the chief metabolic phenotype in cancer and is reflected by the dominance of aerobic glycolysis over minimal-to-no viable oxidative phosphorylation in cancer. Conversely, during the pathogenesis of type 2 diabetes (T2D), oxidative phosphorylation is constantly heightened. In advanced insulin resistance and T2D, the metabolic landscape becomes more complex, with exacerbating metabolic alterations affecting oxidative phosphorylation in a tissue-specific manner. Promising nutritional adjuvants, such as alpha-lipoic acid and flavonoids, can reprogram metabolism and exert antitumor and antidiabetic effects. Other pharmacological agents, such as metformin, have therapeutic effects on cancer and T2D. Herein, we discuss the molecular mechanisms and signaling pathways involved in the metabolic shifts in cancer and T2D, and explore the therapeutic strategies under investigation that aim to reverse the metabolic shift in both disease scenarios.

When wastewater containing methylene blue, a cationic dye is improperly treated or immediately dumped into the environment, it can degrade the quality of water bodies and contaminate the ecological environment. The removal of methylene blue from the aqueous solution is critical and urgent. The present work focuses on the use of maize stalk agricultural waste to prepare an adsorbent for the removal of cationic dye (methylene blue) from an aqueous solution. The prepared maize stalk biochar (MSB) was modified with MnO2 and the modified maize stalk biochar was characterized using Fourier transform infrared (FTIR) spectroscopy. Taguchi technique was employed to determine the optimum conditions for the removal of methylene blue (MB) dye from aqueous solution by MMSB. The factors were adsorbent dose (0.5, 1.0 and 1.5 g/100 mL), initial dye concentration (100, 200 and 300 mg/L), contact time (30, 60, 90 minutes) and pH (4, 6 and 8). Among the investigated process factors, adsorption efficiency was influenced by adsorbent dose and initial MB dye concentration. The optimum parameters were 1 g/100 mL adsorbent dose, 100 mg/L initial dye concentration, 60 minutes contact time and a pH of 8.0. This yielded a removal efficiency of 87.49% with adsorption capacity of 206.53 mg/g. The adsorption kinetics agreed with the pseudo-second-order (R2 of 0.999968) model and fitted a Langmuir isotherm (R2 of 0.9795) representing homogeneous monolayer chemisorption.

The various methods used to choose the profile shift coefficients, primarily the so-called equalizations, were based on assumed advantages without physical evidence proving them. In this paper a new calculation method is presented for determining profile shift coefficient. The procedure gives the pair of values ​​of the profile shift coefficients, in which case, under the given load, the resulting bending stress will be of the lowest possible value.

Salting influences microbial growth, enzymatic activity and biochemical reactions during ripening, thus contributing to the final quality of cheese. The aim of this study was to evaluate the influence of different salting methods (dry salting at 12, 24 and 48 h; in brine; and curd salting) on the chemical (moisture and salt content), physico-chemical (pH, titratable acidity and water activity) and sensory (texture profile analysis, colour and sensory attributes) characteristics of an industrial blue vein cheese. Dry salted cheeses had lower moisture content and water activity, and higher salt/moisture content and acidity than those salted in brine and curd. Dry-salted cheeses were also characterised by higher values for hardness, fracturability and instrumental gumminess. Dry-salted cheeses showed differences only in the red/green colour component (a*), with the curd-salted cheeses being less greenish. All cheeses scored high (around 7) in the tasters' overall impression, with the dry-salted cheeses at 12 and 24 h showing optimal growth and even distribution of mould, as well as better flavour and texture.

“Blue carbon”, apart from marine humus, includes the carbon (C) stock of coastal ecosystems such as mangroves, marshes, and seagrass meadows, which have been overlooked until recently. Information about the role of coastal wetlands in C sequestration and providing other ecosystem services is still insufficient. In the present study, we assessed the C reserves of soils and vegetation biomass in two complex coastal landscapes (tombolos) located on the coasts of the White and Baltic seas. The soil and plant C stocks were slightly higher at the plot at the Baltic Sea (93.4 ± 46.7 Mg C·ha-1 and 5.22 ± 2.51 Mg C·ha-1, respectively) than at the plot on the White Sea (71.4 ± 38.2 Mg C·ha-1 and 3.95 ± 2.42 Mg C·ha-1, respectively). We attributed the higher values of the C reserved to a warmer climate and less saline water at the plot on the Baltic Sea. Both soil and plant C showed high heterogeneity due to geomorphological complexity and differences in vegetative communities. The Phragmites australis community showed the highest plant biomass and, in some places, high soil C reserves. Allochthonous C contributed to the soil C stock at the site on the White Sea. Though P. australis sequestered more C than other communities, its effect on ecosystem services was mostly negative because the invasion of reeds reduced the biological diversity of the marshes.

A unique method for synthesizing a surface modifier for metallic hydrogen permeable mem-branes based on non-classic bimetallic pentagonally structured Pd-Pt nanoparticles has been de-veloped. It was found that nanoparticles had unique hollow structure. This significantly reduces the cost of their production due to economical use of metal. According to the results of electro-chemical studies, synthesized bimetallic Pd-Pt/Pd-Ag modifier showed excellent catalytic activi-ty (up to 60.72 mA cm–2), long-term stability and resistance to COads poisoning in alkaline oxida-tion reaction of methanol. The membrane with pentagonally structured Pd-Pt/Pd-Ag modifier showed the highest hydrogen permeation flux density up to 27.3 mmol s–1 m–2. Obtained hy-drogen flux density were 2 times higher than that for membranes with classic Pdblack/Pd-Ag modifier and an order of magnitude higher than that for unmodified membrane. Since the rate of transcrystalline hydrogen transfer through a membrane increased, while the speed of transfer through defects remained unchanged, a one and a half times rise in selectivity of the developed Pd-Pt/Pd-Ag membranes was recorded and it amounted to 3514. Achieved results are due to both the synergistic effect of the combination of Pd and Pt metals in the modifier composition and the large number of available catalytically active centers, which are present as a result of non-classic morphology with high-index facets. The specific faceting, defect structure and unusual properties provide great opportunities for the application of nanoparticles in the areas of membrane reac-tors, electrocatalysis, petrochemical and hydrogen industries.

Organic light-emitting diodes (OLEDs) have ushered in a technological revolution with their remarkable impact on diverse sectors of our daily lives. These versatile devices known for their outstanding display and lighting capabilities, have become indispensable components in various industries including smartphones, tablets, televisions, and automotive applications. This paper delves into the development of a group of twisted donor-acceptor-donor (D-A-D) derivatives incorporating bicarbazole and benzophenone structures for potential use as blue emitters in OLEDs. The synthesized compounds, namely DB14, DB23 and DB29, were designed with various alkyl side chains to enhance their film forming properties as for blue emitters. Characterization and evaluation of these derivatives included photophysical, electrochemical, thermal, and electroluminescent analysis. Some of the OLED devices incorporating these emitters demonstrated promising performance with maximum current efficiency (CEmax) of 2.6 cd/A and external quantum efficiency (EQEmax) of 5.3%. Notably, the DB23 emitter exhibited the highest EQE among all devices. The study also emphasizes the influence of host-guest energy transfer, optimal doping concentrations, and molecular structures on device performance. This research not only contributes to the understanding of advanced OLED materials but also provides insights into designing efficient blue emitters for future display and lighting applications, thereby advancing the field of organic electronics.

Abstract: Agriculture uses plastic products for containers, packaging, tunnels, drip irrigation tub-ing, mulches. Large amounts of plastics are used as mulches on the soil surface for vegetable pro-duction (tomato, cucumber, watermelon, strawberry, vine) to reduce the weed competition, in-crease water and fertilizer use efficiency and enhance crop yield. Portugal uses around 4,500 t/year of polyethylene plastic to cover approximately 23,000 ha of agricultural land and only a small amount is recovered for recycling or secondary uses because of dirt with soil, vegetation, pesticide and fertilizers. Cleaning and decontaminating polyethylene mulch are costly and commercial technology is often not accessible nor economically viable in the current economic Portuguese situation. Most plastic mulch is composed of polyethylene that degrades slowly and produces a large quantity of residues in soil with negative impact in the environment. In the present study, the effects of long-term cultivation of blueberry using green 100% high density polyethylene mulch, in the south Portugal were evaluated for soil chemical and biological changes. High density green plastic mulch did not contaminate the topsoil with di(2-ethylhexyl) phthalate and heavy metals, buttotal nitrogen and organic carbon concentrations, electric conductivity and microbial activity were reduced in the planting row compared with bare soil, without mulching. Further-more, the presence of plastic mulch did not affect negatively the presence of nematodes, and the Rhabditida (bacterial feeders) increased in the planting and covered row.

Antibiotic-free approaches are more important than ever to deal with the rapidly growing problem of antibiotic resistance. The blue light 460nm (BL460nm) has been shown to effectively attenuate Staphylococcus aureus to chemical and physical agents through photolysis of the bacterial virulence factor Staphyloxanthin. However, the phototherapy using BL640nm has yet to be investigated in detail for its safety in eradicating Staphylococcus aureus in vitro and in vivo. In this study, we used a LED source producing a continuous wavelength of 460 nm along with hydrogen peroxide to treat S. aureus in culturing conditions and a wound abrasion mouse model. The results proved the safety of the combined therapy when it did not modify the bacterial virulence factors or the susceptibility to the widely used antibiotics. In addition, the experimental results on the mouse skin infection model also showed that the combined therapy is safe to apply to mouse skin and that it did not cause adverse skin irritation. Furthermore, the therapy can help Staphylococcus aureus-infected wounds heal with efficacy comparable to the topical antibiotic Fucidin. The above results suggest that the combination therapy of 460nm blue light and hydrogen peroxide can be safely used as an alternative to or adjunct to antibiotics in treating S. aureus-infected wounds.

In physics, thought experiments are impressive heuristic tools. They are valuable instruments to help scientists find new results and to teach students the known ones. However, as we shall show, they should always be received with prudence, even when they are a shortcut to 'prove' well-established results. Here, we show that the most widely known thought experiments devised to derive the gravitational frequency shift from energy conservation are, in fact, problematic. When properly set and correctly read, those thought experiments reveal that the existence of the gravitational frequency shift is, in fact, at odds with energy conservation. We also propose two new simple thought experiments, one using the conservation of energy and the other the conservation of linear momentum, that corroborate that conclusion, showing that those conservation principles do not imply the gravitational frequency shift. We think that our results may be of some epistemological interest and could serve as a warning sign on how thought experiments should be received and trusted.

The work carried out first-principles calculations within the framework of density functional theory to study the structural stability of the CsSnI₃ compound and the influence of phase transitions on their electronic and optical properties. Using the GGA and SCAN functionals, the relaxed structures of the CsSnI₃ phases were obtained and their geometric characteristics were assessed. Using the Phonopy code based on VASP, calculations of phonon and thermodynamic properties were performed, and the temperatures of phase transitions of CsSnI₃ were determined. The temperature dependences of the thermodynamic parameters α-, β-, γ- and δ-phases of CsSnI₃ were analyzed. The trends in free energy, entropy, enthalpy, heat of formation energy and heat capacity were justified in terms of the pattern of changes in the total energy of the four phases of CsSnI₃ from VASP calculations. It is shown that at 0 K the non-perovskite structure of the CsSnI₃ compound (δ-CsSnI₃) is the most stable (followed by γ-CsSnI₃), and the tetragonal phase (β) is quite unstable, having the highest energy among the perovskite phases. It was revealed that at temperatures above 450 K the tetragonal phase becomes stable, and when the temperature drops, it transforms into the cubic phase (α-CsSnI₃). The phase transition between the β and γ phase of perovskite occurs in the range of 300-320 K, and at 320 K a black-yellow transformation of CsSnI₃ occurs in which the cubic phase (black perovskite) undergoes a phase transition to a non-perovskite conformation (yellow phase). The presence of temperature phase transitions between two orthorhombic phases of CsSnI₃ at 360 K was discovered, although direct transitions of the α⟷γ and γ⟷δ types have not yet been reported in any experiment, except for γ→δ transitions under the influence of moisture. Based on well-relaxed structures (from the SCAN calculations), the band gap widths for four CsSnI₃ phases were calculated and compared with experimental measurements. Electronic properties and Fermi level shifts as a result of phase transformations of CsSnI₃ were assessed using the HSE06 functional and machine learning prediction. The values of the complex dielectric constant and the refractive index of all phases of the CsSnI₃ were determined.

This study aimed to assess the impact of different modes of laser irradiation on the bactericidal efficacy of aPDT. Dentin plates were prepared by sectioning the crown dentin of bovine teeth infected with Streptococcus sobrinus. Nine aPDTs involving the combinations of three photosensitizers (brilliant blue, BB; acid red, AR; and methylene blue, MB) and three laser irradiation modes (50 mW for 120 s, 100 mW for 60 s, and 200 mW for 30 s) were performed for each infected dentin plate, and the control group consisted of the specimens not applied with aPDT. The bactericidal effects in 10 experimental groups were evaluated (n=11) using both assays of the colony-count and adenosine triphosphate (ATP). The data obtained were analyzed using the Kruskal-Wallis test. The aPDT performed with semiconductor laser in combination with BB, AR, and MB exerted a remarkable bactericidal effect. aPDT with MB exerted a more significant bactericidal effect in the colony-count assay. The results of aPDT performed with varying irradiation times and powers but with constant irradiation energy showed no difference with AR and MB between the modes, whereas BB showed a more significant bactericidal effect when irradiated for a shorter time at a higher irradiation power.

The cosmetic industry has a history of constant modernization, with products that are increasingly sustainable and well tolerated by the customers. In the last years, the growing understanding and knowledge of the potential of marine species, as well as the application of “blue biotechnology” have been motivating new innovative solutions in this area. Marine organisms are important sources of compounds that may be applicable in cosmetics, with biological activities that include depigmentant, anti-aging or anti-bacterial properties, specifically against acne, but also as formulation promoters and facilitators. Several methods can be used to extract these molecules, but these are not free of challenges and implications – possible biological and chemical contamination, and problems with batch reproducibility, which can be associated to the intraspecific variability of the different specimens, should be considered. Alongside these, the legislative and normative framework is increasingly developed and there is a growing concern with this situation. The application of sustainability fundamentals in the production of cosmetics must respect a life cycle approach, critically analyzing each stage. In this sense, “blue biotechnology”, in constant evolution, together with the use of invasive species or marine waste products to obtain new active ingredients, emerge as innovative and sustainable solutions for the future’s cosmetics industry. This review explores various biological properties of marine-derived molecules and discusses the challenges and implications associated with extracting these compounds. It also examines recent advancements in 'blue biotechnology' and their relevance to the sustainable development of innovative cosmetics.

Antimicrobial photodynamic therapy (aPDT) used to sterilize carious dentin may irritate the pulp tissues because of tissue-penetrating laser and singlet oxygen generation. This study aimed to assess the effects of aPDT on rat pulp tissues. A cavity formed in a rat maxillary first molar was treated with aPDT. The combined photosensitizer and laser irradiation conditions in the aPDT groups were as follows: methylene blue and 100 mW for 60 s, brilliant blue (BB) and 100 mW for 60 s, BB and 50 mW for 120 s, and BB and 200 mW for 30 s. Each cavity was treated with an all-in-one adhesive and filled with flowable resin. aPDT was not applied for the control. In each group, the rats were sacrificed on postoperative days 1 and 14, and thin sections of the treated teeth were prepared. Pulp tissue disorganization (PTD), inflammatory cell infiltration (ICI), and tertiary dentin formation (TDF) were evaluated. At 1 day evaluation, there were significant differences between the aPDT group and controls with respect to PTD and ICI. 14 days later, almost all specimens showed tertiary dentin formation. aPDT caused temporarily reversible injury to the rat dental pulp, which healed with tertiary dentin formation.

The effect of Localized Surface Plasmon (LSP) of 5 nm mean size Au particles deposited on TiO2 P25 was investigated during the photo-thermal water gas shift reaction (WGSR). The effects of CO concentration, excitation light flux and energy, and molecular oxygen addition during the reaction were investigated. The photocatalytic WGSR rate under light excitation with wavelengths extending from 320 to 1100 nm was found to be higher than the thermal reaction alone at the same temperature (85 oC). A ratio H2/CO2 of near unity was found at high concentrations of CO. Addition of molecular oxygen during the reaction resulted in a slight decrease of molecular hydrogen production while the rates of CO2 formation and that of CO consumption changed by one order of magnitude. More important, it was found that the WGSR rates were still high under only visible light excitation (600 - 700 nm). The results prove that Au LSP alone triggers this chemical reaction without the need to excite the semiconductor on which they are deposited.

This research work deals with the formulation of numerical scheme with algorithm to compute singularly perturbed partial differential equations(SP-PDEs) involving a significant negative shift. The problem involves small parameter which causes a rapidly changing boundary layers in the vicinity of a body, and the negative shift term causes interior layer. Such appearance of an abruptly varying layers causes difficulties to find the exact solution and it is not adequate to employ classical numerical methods. The technique presented in this research work simplifies these challenges and yields accurate numerical solution.The stability and convergence analyses of the methods are examined and proven. To test the developed technique, numerical experiments are carried out and confirmed with theoretical analysis.

Water pollution, driven largely by the discharge of organic dyes from various industrial processes, presents a grave environmental threat. This study delves into the promise of an innovative adsorptive composite material composed of chitosan and activated charcoal, offering a sustainable and efficient solution for removing methylene blue (MB) dye from water sources. Our comprehensive investigation encompasses the synthesis, characterization, and adsorption capabilities of this composite material, revealing its remarkable physicochemical attributes and its substantial capacity to adsorb MB dye. These findings establish it as a compelling candidate for water treatment applications. The assessment of adsorbent dosage shows a direct correlation between higher dosages and enhanced MB dye removal, with an optimal dosage determined at 0.4 g/25 mL. Furthermore, pH-dependent studies demonstrate exceptional performance at lower pH levels, achieving an impressive 95% removal rate at pH 3 after 240 minutes of contact time. The composite exhibits consistent high removal percentages across a wide range of MB dye concentrations, showcasing its adaptability. In terms of reaction time, the composite achieves peak adsorption capacity within the initial 360 minutes and maintains a stable equilibrium, sustaining an impressive 99% removal efficiency thereafter. This study underscores the eco-friendliness and cost-effectiveness of the composite material, emphasizing its potential to address water pollution challenges and promote sustainable water resource management. Overall, this research yields valuable insights into a practical approach for mitigating the adverse impact of organic dyes on aquatic ecosystems and public health.

Key elements of Blue-Green Infrastructure are vegetation and stormwater storage. A combination of a bioretention cell with an underlying trench (BC-T) serving as a tree pit is often used in dense urban environments. An adequate ratio of drained area to bioretention cell area is a crucial design parameter. The ratio is derived from the hydrological balance; however, input data are often difficult to obtain or uncertain. The goal is to study the sensitivity of such data (tree water uptake and water holding capacities of soil filter and trench substrate) in the BC-T design. Sensitivity analysis is performed for the setup of a BC-T used in Prague, Czech Republic. A 10-year rainfall series (1 hour resolution) is used as an input. Data that are subject to the sensitivity analysis are changed for different trench exfiltration rates, and the effect on the size of the drained area is studied. At low trench exfiltration rates (1.8 mm.h-1), both the water holding capacity of the trench substrate and potential tree water uptake have a significant influence (more than a 20% change in the size of the drained area) and cannot be neglected. At good exfiltration rates (more than 18 mm.h-1) or when the trench is equipped with an underdrain, all studied parameters can be neglected. However, it is recommended to reduce the size of the drained area by 10-20%.

Optical network monitoring and soft failure identification such as optical filter shifting and filter tightening is increasingly significant in the future complex and dynamic optical networks. Center frequency shift of optical filtering device in optical network has a serious impact on the perfor-mance of multi-span transmission, especially in high spectrum efficiency faster-than-Nyquist (FTN) transmission systems with various optical switching and add/drop nodes. Existing moni-toring schemes generally have problem of high cost, high complexity and the inability to realize multi-channel online monitoring, which makes it difficult to be applied in wavelength division multiplexing (WDM) system with numerous nodes. In this paper, a monitoring scheme of fre-quency shift of optical filtering devices based on optical label (OL) is proposed and demonstrated. The signal spectrum of each channel is intentionally divided into many sub-bands with corre-sponding optical labels loading. The characters of spectrum power changing caused by frequency shift can be reflected on labels power changing of each sub-band, which are used to monitor and estimate the value of frequency shift by DSP algorithm. Simulation results shows that the that the monitoring errors of frequency shift can be kept below 0.5GHz reasonably after 10-span WDM transmission in FTN polarization multiplexing m-ary quadrature amplitude modulation (PM-mQAM) systems. In addition, 250km fiber transmission experiments are also carried out and the similar results are obtained, which further verify the feasibility of our proposed scheme. The characters of low cost, high reliability and efficiency make it a better candidate for practical ap-plication in the future FTN WDM networks.

The main objective of the paper is to provide a thorough analysis of currently used modulation control schemes for single phase bidirectional dual active bridge DC/DC converter. In this article, it will be shown that single phase shift, extended phase shift and Dual phase shift modulation schemes are special cases of triple phase shift (TPS) modulation scheme. The article aims to highlight six TPS switching modes and their complements with the operational constraints. Unlike previous studies that regarded TPS as a complex scheme, this paper simplifies the analysis of each mode and aims to standardize the understanding of TPS modulation in DAB converters. Power equations, range of power transferred and zero voltage switching (ZVS) are derived for all the modes under TPS without assuming fundamental component analysis. Additionally, a generic optimization algorithm is developed to show the advantages of TPS modulation and thus, detailed analysis presented in this paper provides valuable insights for single phase DAB converter designers in identifying a wide range of optimization algorithms to achieve higher efficiency under TPS modulation. This analysis contributes to the advancement of bidirectional DAB converter technology and facilitates its application in various power electronic systems.

Our skin is constantly exposed to blue light (BL), which is abundant in sunlight and emitted by digital devices. Prolonged exposure to BL can lead to oxidative stress-induced damages and skin hyperpigmentation. In this study, we investigated the protective effects of tocotrienol-rich fraction (TRF) on BL-induced oxidative stress and hyperpigmentation in B16-F1 melanocytes. Alpha-tocopherol (αTP) was used as a comparator. Our results showed that TRF effectively suppressed the formation of reactive oxygen species, and preserved the mitochondrial membrane potential. Additionally, TRF exhibited anti-apoptotic properties by reducing the activation of p38 mitogen-activated protein kinase molecule and downregulating the expression of cleaved caspase-3. Moreover, TRF modulated tyrosinase activity, resulting in a lowered rate of melanogenesis and reduced melanin production. In contrast, αTP did not exhibit the significant protective effects against skin damages and pigmentation in BL-induced B16-F1 cells. Therefore, this study indicates that TRF may offer superior protective effects over αTP against the effects of BL on melanocytes. These findings demonstrate the potential of TRF as a protective natural active against BL-induced skin damages and hyperpigmentation via its antioxidative and anti-melanogenic properties.

The research paper provides a mathematical framework for understanding phase shift in wave phenomena, bridging theoretical foundations with real-world applications. It emphasizes the importance of phase shift in physics and engineering, particularly in fields like telecommunications and acoustics. Key equations are introduced to explain phase angle, time delay, frequency, and wavelength relationships. The study also introduces the concept of time distortion due to a 1° phase shift, crucial for precise time measurements in precision instruments. The research also addresses infinitesimal wave energy loss related to phase shift, enriching our understanding of wave behavior, and impacting scientific and engineering disciplines.

In this study, we considered the structural stability, electronic properties, and phonon dispersion of the cubic (c-ZrO₂), tetragonal (t-ZrO₂), and monoclinic (m-ZrO₂) phases of ZrO₂. We found that the monoclinic phase of zirconium dioxide is the most stable among the three phases in terms of total energy, lowest enthalpy, highest entropy, and other thermodynamic properties. The smallest negative modes were found for m-ZrO₂. Our analysis of the electronic properties showed that during the m–t phase transformation of ZrO₂, the Fermi level first shifts by 0.125 eV toward higher energies and then decreases by 0.08 eV in the t–c cross-section. The band gaps for c-ZrO₂, t-ZrO₂, and m-ZrO₂ are 5.140 eV, 5.898 eV, and 5.288 eV, respectively. Calculations based on the analysis of the influence of doping 3.23, 6.67, 10.35, and 16.15 mol. %Y₂O₃ onto the m-ZrO₂ structure showed that the enthalpy of m-YSZ decreases linearly, which accompanies further stabilization of monoclinic ZrO₂ and an increase in its defectiveness. A doping-induced and concentration-dependent phase transition in ZrO₂ under the influence of Y₂O₃ was discovered, due to which the position of the Fermi level changes and the energy gap decreases. It has been established that, not only for pure systems but including those doped with Y₂O₃, the main contribution to the formation of the conduction band is made by the p-states of electrons. The t-ZrO₂ (101) and t-YSZ (101) surface models were selected as optimal surfaces for water adsorption based on a comparison of their surface energies. An analysis of the mechanism of water adsorption on the surface of t-ZrO₂ (101) and t-YSZ (101) showed that H₂O on unstabilized t-ZrO₂ (101) is adsorbed dissociatively with an energy of -1.22 eV, as well as by the method of molecular chemisorption with an energy of - 0.69 eV and the formation of a hydrogen bond with a bond length of 1.01 Å. In the case of t-YSZ (101), water is molecularly adsorbed onto the surface with an energy of -1.84 eV. Dissociative adsorption of water occurs at an energy of -1.23 eV, near the yttrium atom. The results show that ab initio approaches are able to describe the mechanism of doping-induced phase transitions in (ZrO₂+Y₂O₃)-like systems, based on which it can be assumed that DFT calculations can also flawlessly evaluate other physical and chemical properties of YSZ, which have not yet been studied quantum chemical research. The obtained results complement the database of research works carried out in the field of the application of biocompatible zirconium dioxide crystals and ceramics in green energy generation and can be used in designing humidity-to-electricity converters and creating solid oxide fuel cells based on ZrO₂.

In this study, we considered the structural stability, electronic properties, and phonon dispersion of the cubic (c-ZrO₂), tetragonal (t-ZrO₂), and monoclinic (m-ZrO₂) phases of ZrO₂. We found that the monoclinic phase of zirconium dioxide is the most stable among the three phases in terms of total energy, lowest enthalpy, highest entropy, and other thermodynamic properties. The smallest negative modes were found for m-ZrO₂. Our analysis of the electronic properties showed that during the m–t phase transformation of ZrO₂, the Fermi level first shifts by 0.125 eV toward higher energies and then decreases by 0.08 eV in the t–c cross-section. The band gaps for c-ZrO₂, t-ZrO₂, and m-ZrO₂ are 5.140 eV, 5.898 eV, and 5.288 eV, respectively. Calculations based on the analysis of the influence of doping 3.23, 6.67, 10.35, and 16.15 mol. %Y₂O₃ onto the m-ZrO₂ structure showed that the enthalpy of m-YSZ decreases linearly, which accompanies further stabilization of monoclinic ZrO₂ and an increase in its defectiveness. The doping-induced and concentration-dependent phase transition of zirconium dioxide under the influence of yttrium oxide was studied, after which the position of the Fermi level changes and the energy gap decreases. It has been established that, not only for pure systems but including those doped with Y₂O₃, the main contribution to the formation of the conduction band is made by the p-states of electrons. The t-ZrO₂ (101) and t-YSZ (101) surface models were selected as optimal surfaces for water adsorption based on a comparison of their surface energies. An analysis of the mechanism of water adsorption on the surface of t-ZrO₂ (101) and t-YSZ (101) showed that H₂O on unstabilized t-ZrO₂ (101) is adsorbed dissociatively with an energy of -1.22 eV, as well as by the method of molecular chemisorption with an energy of -0.69 eV and the formation of a hydrogen bond with a bond length of 1.01 Å. In the case of t-YSZ (101), water is molecularly adsorbed onto the surface with an energy of -1.84 eV. Dissociative adsorption of water occurs at an energy of -1.23 eV, near the yttrium atom. The calculations showed that ab initio research methods are capable of describing the mechanism of phase transitions of materials under the influence of alloying. That is, by optimizing the parameters of DFT calculations, it is possible to observe the effects of doping on other physical and chemical properties of materials, which are still beyond the scope of quantum chemical modeling. The obtained results complement the database of research works carried out in the field of the application of biocompatible zirconium dioxide crystals and ceramics in green energy generation and can be used in designing humidity-to-electricity converters and creating solid oxide fuel cells based on ZrO₂.

The prevalence of digital devices in modern society has raised concerns about the potential neg-ative effects of blue light emissions on eye health and biological rhythms. Research into blue light emissions from digital devices and their potential impact on eye health emphasizes the importance of understanding and quantifying the extent and scope of blue light emissions produced by commonly used screens (smartphones, tablets and computers). This comparative study specifically evaluates three popular Apple devices: iPhone 12 mini®, iPad Pro 12.9® and MacBook Pro®. The devices' spectral power was measured using a spectroradiometer while displaying text and a game at different brightness levels. The study also examines the effectiveness of blue-blocking lenses from well-known brands. The research highlights the importance of quantifying blue light emissions and understanding their potential impact on eye health. By doing so, appropriate measures can be developed to mitigate adverse effects on ocular structures. Above all, this research provides valuable information about the risks associated with exposure to blue light, showing that all tested devices have blue wavelength peaks between 445 nm and 455 nm. By recognizing and addressing the potential negative impacts of blue light, the risks of eye health problems can be reduced and ensure more responsible and conscious use of digital devices.

The integration of the increasing share of Renewable Energy Sources (RES) requires the availability of suitable energy storage systems to improve the grid flexibility, and Compressed Air Energy Storage (CAES) systems could be a promising option. In this study, a CO2-free Diabatic CAES system is proposed and analysed. The plant configuration is derived from a down-scaled version of the McIntosh diabatic CAES plant, where the natural gas is replaced with green hydrogen, produced on site by a Proton Exchange Membrane electrolyser powered by a Photovoltaic power plant. In this study, the components of the hydrogen production system are sized to maximize the Self-Consumption share of PV energy generation and the effect of the design parameters on the H2-CAES plant performance are analysed on a yearly basis. Moreover, a comparison between the use of natural gas and hydrogen in terms of energy consumption and CO2 emissions is discussed. The results show that the proposed hydrogen fuelled CAES can effectively match the generation profile and the yearly production of the natural gas fuelled plant by using all the PV energy production, while producing zero CO2 emissions.

In this study, we considered the structural stability, electronic properties, and phonon dispersion of the cubic (c-ZrO₂), tetragonal (t-ZrO₂), and monoclinic (m-ZrO₂) phases of ZrO₂. We found that the monoclinic phase of zirconium dioxide is the most stable among the three phases in terms of total energy, lowest enthalpy, highest entropy, and other thermodynamic properties. The smallest negative modes were found for m-ZrO₂. Our analysis of the electronic properties showed that during the m–t phase transformation of ZrO₂, the Fermi level first shifts by 0.125 eV toward higher energies and then decreases by 0.08 eV in the t–c cross-section. The band gaps for c-ZrO₂, t-ZrO₂, and m-ZrO₂ are 5.140 eV, 5.898 eV, and 5.288 eV, respectively. Calculations based on the analysis of the influence of doping 3.23, 6.67, 10.35, and 16.15 mol. %Y₂O₃ onto the m-ZrO₂ structure showed that the enthalpy of m-YSZ decreases linearly, which accompanies further stabilization of monoclinic ZrO₂ and an increase in its defectiveness. In this case, the position of the Fermi level changes abruptly, and the energy gap decreases. It has been established that, not only for pure systems but including those doped with Y₂O₃, the main contribution to the formation of the conduction band is made by the p-states of electrons. The t-ZrO₂ (101) and t-YSZ (101) surface models were selected as optimal surfaces for water adsorption based on a comparison of their surface energies. An analysis of the mechanism of water adsorption on the surface of t-ZrO₂ (101) and t-YSZ (101) showed that H₂O on unstabilized t-ZrO₂ (101) is adsorbed dissociatively with an energy of -1.22 eV, as well as by the method of molecular chemisorption with an energy of - 0.69 eV and the formation of a hydrogen bond with a bond length of 1.01 Å. In the case of t-YSZ (101), water is molecularly adsorbed onto the surface with an energy of -1.84 eV. Dissociative adsorption of water occurs at an energy of -1.23 eV, near the yttrium atom. The obtained results complement the database of research works carried out in the field of the application of biocompatible zirconium dioxide crystals and ceramics in green energy generation and can be used in designing humidity-to-electricity converters and creating solid oxide fuel cells based on ZrO₂.

We recently developed a novel hyperspectral excitation-resolved near-infrared fluorescence imaging system (HER-NIRF) based on a continuous-wave wavelength-swept laser. In this study, this technique is applied for measuring the distribution of the therapeutic agent dimethyl sulfoxide (DMSO) by utilizing solvatochromic shift in the spectral profile of albumin-bound Indocyanine green (ICG). Using wide-field imaging in turbid media, complex dynamics of albumin-bound ICG is measured in mixtures of dimethyl sulfoxide (DMSO) and water. Phantom experiments are conducted to evaluate the performance of the HER-NIRF system. The results show that the distribution of DMSO can be visualized in the wide-field reflection geometry. One of the main purposes of the DMSO is to act as a carrier for other drugs, enhancing their effects by facilitating skin penetration. Understanding solubility and permeability of drugs in vivo is very important in drug discovery and development. Hence, this HER-NIRF technique has a great potential to advance the utilization of the therapeutic agent DMSO by mapping its distribution via solvatochromic shift of ICG. By customizing the operational wavelength range, this system can be applied to any other fluorophores in the near infrared region and utilized for a wide variety of drug delivery studies.

The development and use of selenium and iodine elements in agriculture aim to enrich agricultural food products for humans. This study was carried out as a three-factor factorial experiment in a completely randomized design (CRD). Three concentrations of sodium selenate fertilizer (0, 2, 4 mg/l), three potassium iodate (0, 2, 4 mg/l), and two supplementary radiation levels (blue light and sunlight) were used. The results showed that the highest and the lowest (3.44 & 3.12 mg/g f.w) leaf protein value was related to blue light and sunlight treatments, respectively. In the blue light treatment, the maximum and the minimum (4.77 & 3.39 mg/g f.w) leaf sugar amount was observed at 4 and 0 mg/l of the iodine, respectively. At 0 mg/l of selenium, the highest and the lowest (8.63 & 5.34 mg/g f.w) leaf vitamin C amount was recorded at the 4 and 0 mg/l of iodine, respectively. In blue light + 0 mg/l of the selenium, the highest and the lowest (2.94 & 2.10 mg/g f.w) leaf flavonoid quantity was seen at 2 and 0 mg/l of the iodine, respectively. In the blue light conditions, (5.20%) leaf nitrogen content was achieved in the selenium 4 mg/l group. In the same conditions, the maximum and the minimum (3.09 & 2.18%) leaf potassium amount was attained at selenium 2 and 4 mg/l, respectively. Under blue light conditions, the highest and the lowest (0.58 & 0.24 mg/kg dry matter) leaf selenium level was observed at 4 and 0 mg/l, respectively. In sunlightradiation levels, the maximum and the minimum (0.36 & 0.25 mg/kg dry matter) leaf selenium level were found at 4 and 0 mg/l of selenium, respectively. In the blue light conditions, the most and the lowest (1.65 & 0.72 mg/kg dry matter) seed selenium content was related to 4 and 0 mg/l of the selenium, respectively. In the blue light conditions, the highest and the lowest (8.49 & 4.25 mg/kg dry matter) leaf iodine level was recorded at 4 and 0 mg/l of iodine, respectively. In the blue light conditions, the maximum and the minimum (30.56 & 20.62 mg/kg dry matter) seed iodine value was related to 4 and 0 mg/l of the iodine, respectively. In the sunlight, the most and the lowest (24.96 & 20.29 mg/kg dry matter) seed iodine amount was achieved at 4 and 0 mg/l of the selenium, respectively.

Oral ferric citrate hydrate (FCH) is effective for iron deficiency in hemodialysis patients.; however, it remains unclear how iron balance in the body affects iron absorption from the intestinal tract. This prospective, observational study (Riona-Oral Iron Absorption Trial, R-OIAT, UMIN 000031406), conducted at 42 hemodialysis centers in Japan, wherein 268 hemodialysis patients without inflammation were enrolled and treated with a fixed amount of FCH for 6 months. We assessed the predictive value of hepcidin-25 for iron absorption and iron shift between ferritin (FTN) and red blood cells (RBCs) following FCH therapy. Serum iron changes at 2 h (ΔFe2h) after FCH ingestion were evaluated as iron absorption. The primary outcome was the quantitative delineation of iron variables on ΔFe2h and the secondary outcome was the description of the predictors of body iron balance. Generalized estimating equations (GEE) were used to identify the determinants of iron absorption during each phase of FCH treatment. ΔFe2h increased when hepcidin-25 and MCH decreased (-0.155, -0.242 to -0.068, p = 0.001; -2.574, -4.421 to -0.726, p = 0.006, respectively) in GEE. Hepcidin-25 increased when erythropoiesis-stimulating agent (ESA) decreased (-0.002, -0.002 to -0.001, p=0.000). FTN increased when RBC and ESA decreased (-0.466, -0.605 to -0.327, p=0.000; -0.002, -0.004 to -0.000, p=0.05, respectively. Limiting erythropoiesis to maintain hemoglobin levels induces RBC reduction in hemodialysis patients, resulting in increased hepcidin-25 and FTN levels. Hepcidin-25 production may prompt an iron shift from RBC-iron to FTN-iron, inhibiting iron absorption even with continued FCH intake.

Taking advantage of fact that the surface electrons of metallic nanoparticles (NPs) can be effectively released even at a low voltage bias, we demonstrate an improvement in the electrochemical performance of nano-sized Prussian Blue (PB) based secondary batteries by the incorporation of bare Ag or Ni NPs onto the vicinity of the working PB NPs. It is found that the capacity for electrochemical energy storage of the 17-nm-PB-based battery is significantly higher than the capacity of 10-nm-PB-based, 35-nm-PB-based or 46-nm-PB-based batteries. There is a critical PB size for the highest electrochemical energy storage efficiency. The full specific capacity CF of the 17-nm-PB-based battery stabilized to 62 mAh/g after 130 charge-discharge cycles at a working current of IW = 0.03 mA. The addition of 14 mass-percent of Ag NPs in the vicinity of the PB NPs gives rise to a 32% increase in the stabilized CF. A 42% increase in the stabilized CF can be obtained with the addition of 14 mass-percent of Ag NPs on the working electrode of the 35-nm-PB-based battery. An enhancement of CF is also found for electrodes incorporating bare Ni NPs but the effect is smaller.

With the rapid development in Beijing, there is a critical need to explore the circumstance and reveal the mechanisms of precious urban natural resources. In this context, urban blue space has attracted more and more attention by driving microcirculation, cooling heat islands, and relaxing residential. We extracted the UBS at Beijing using remote sensing, explored the spatial and temporal development in the last two decades via USDA methods, uncovered the full spectrum of landscape patterns from an ecological perspective, and simulated the mechanisms of the UBS area and the landscape quantitatively. We found that: (1) The UBS area in Beijing increased with fluctuation from 2000 to 2020. (2) The spatial clustering has distributed stable with some subtle changes. (3)The ecological circumstance has improved in the last 21 years in Beijing, with the increasing habitat diversity and richness, while the inferior landscape fragmentation has indicated some severe challenges. (4) Natural factors impact urban blue space areas more than social ones, while both similarly influence the UBS landscape. (5) Vegetation circumstances and precipitation are the most important natural factors on both area and landscape of UBS, and population and artificial surface are the most important social factors.

Water pollution with dyes is a critical environmental issue because off the huge amount of dyes disbarred annually which cause severe damage for the ecosystem and human life. On the other hand, the core-shell based magnetic materials have showed amazing character for controlling the material synthesis with targeted structure to enhance the adsorptive-removal of pollutants. Herein, Fe3O4 core-TiO2/mesoSiO2 and Fe3O4 core-mesoSiO2/TiO2 double shell nanoparticles were prepared by first (R1) and second (R2) routes. The preparation procedure is controlled to prepare the magnetic core with further coating layers from silica and titania for the uptake of methylene blue from aqueous solutions. The reported adsorption capacities for R1-0.2, R1-0.4 and R2 samples were 46, 38 and 50 mg/g respectively at pH 6 after 80 min contact time form 50 ppm methylene blue solution. The adsorption process of methylene blue onto Fe3O4core-meso SiO2/TiO2 double shell was well fitted with the pseudo-second-order kinetic model and Freundlish isotherm which suggested the quick and multilayer adsorption mechanism. In addition, results of thermodynamic investigation indicated that the surfaces of Fe3O4 core-mesoSiO2/TiO2 and Fe3O4 core-TiO2/mesoSiO2 double shell exhibit spontaneous tendency to adsorb methylene blue from the aqueous solutions. These results will encourage the further application of Fe3O4 core-meso SiO2/TiO2 and Fe3O4 core-TiO2/meso SiO2 double shell for removal of other dyes and pollutants from wastewater.

As education continues to evolve in response to technological advancements, the concept of Education 5.0 has gained prominence. However, it is crucial to critically analyze the limitations and challenges of this model. This article presents a comprehensive examination of Education 5.0, identifies its drawbacks, and proposes a vision for Education 6.0. Through insightful case studies and discussions, this article aims to provide a nuanced perspective on the future of education.

Molecular structures, in chloroform and DMSO solution, of the monounsaturated free fatty acids (FFAs) caproleic acid (dec-9-enoic acid) and oleic acid (octadec-9-enoic acid) and the ω-3 FFAs α-linolenic acid (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid ALA), eicosapentanoic acid (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid) and docosahexaenoic acid (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid), are reported with the combined use of NMR and DFT calculations. Variable temperature and concentration chemical shifts of the COOH protons and transient 1D NOE experiments, in CDCl3, demonstrate the major contribution of low molecular weight aggregates of dimerized fatty acids, through intermolecular hydrogen bond interactions of the carboxylic groups, with parallel and antiparallel interdigitated structures, even at the low concentration of 20 mM. For the dimeric DHA, a structural model of an intermolecular hydrogen bond through carboxylic groups and an intermolecular hydrogen bond between the carboxylic group of one molecule and the ω-3 double bond of a second molecule, is shown to play a role. In DMSO-d6 solution the centro-symmetric hydrogen bond interactions are broken and the carboxylic groups form strong intermolecular hydrogen bond interactions with a discrete solvation molecule of DMSO. These solvation species form parallel and antiparallel interdigitated structures of low molecular weight. DFT structural models in CHCl3 and DMSO, in agreement with the NMR data, are compared with the structures in the liquid state

We appeal the science community to review the basic definition of wavelength dependent cosmic red shift. We would like to emphasize the point that, the true cosmic red shift must be defined as the ratio of loss in energy of photon to the energy of photon at galaxy. In terms of wavelength, photon red shift must be defined as the ratio of change in wavelength to the observed wavelength of photon. Considering the recent paper pertaining to cosmic halt authored by Cosmin Andrei, Anna Ijjas, and Paul J. Steinhardt and reviewed by Saul Perlmutter, in this paper we propose a very simple model of the universe having early stage light radius of proton seems to be equal to half the product of reduced Planck’s constant and current speed expansion and current stage quantum halt accompanied by continuous light speed rotation. In this context, representing early cosmic expansion and rotation as an outward spiral, it seems possible to consider Hubble’s law as a representation of current cosmic light speed rotation having no further expansion. To understand the current cosmic halt, we are proposing very simple and very strange atomic and nuclear relations that constitute Hubble parameter and gravitational constant. Qualitatively and quantitatively, gravitational potential energy of proton and electron separated by a distance of root mean square radius of proton. Based on uncertainty condition, it needs further study, observations and analysis. We have extended our analysis towards the microscopic coupling constants. Thus, instead of considering the cosmological variable nature of elementary physical constants, we consider the case of current or nearby cosmic halt by means of considering the equality of current cosmic variable physical constants having similar dimensions of fixed elementary physical constants and their combinations. In this connection, it is very interesting to note that, our estimated cosmic age of (2/H0) is matching with recent estimates proposed by Rajendra P Gupta and published in MNRAS.

To increase the efficiency of fuel processor and HT-PEMFC (High Temperature-Proton Exchange Membrane Fuel Cell) combined system, it is essential to improve the efficiency of a fuel processor. In this research, the fuel processor was simulated by Aspen Hysys® simulator, and effect of the various operating conditions on the total efficiency was investigated. Thermal efficiency of the fuel processor increased as the temperature and S/C (Steam to carbon) ratio increased, and the efficiency was higher at the S/C ratio of 3 than at the S/C of 4 at the reformer temperature of 700 ℃ and higher. Under the selected operating conditions of the fuel processor, recycling of unreacted hydrogen from the anode off gas (AOG) of the HT-PEMFC improve the overall efficiency of the combined fuel processer and HT-PEMFC by a factor of 1.28. Operating conditions where the AOG supplied excessive heat than required for fuel processor operation were excluded. The high-efficiency operating conditions of the fuel cell system were proposed with the target of 5 kW of output as the capacity of the household HT-PEMFC.

This study presents a straightforward electrochemical and plasma deposition method for producing Cobalt-doped Blue-TiO2 nanotubes with enhanced catalytic properties. After a titanium plate has been anodized, specific procedures are carried out that cause oxygen vacancies to form inside the TiO2 nanostructures. The obtained catalysts were subjected to electrochemical tests (to identify charge transfer resistance and flat band potential), optical analysis (to determine the band gap and Urbach energy) and also characterized in terms of morphology, wettability and antibacterial effect in order to understand and analyze the impact of the Co doping method on the final catalyst characteristics. A hydrophilic film with star-shaped structures and with antibacterial effect was created when cobalt was electrochemically doped to Blue-TiO2 nanotubes. By using this electrochemical doping technique, the Urbach energy was raised from 1.171 to 3.836 eV while the band gap energy was decreased from 3.04 to 2.88 eV. Additionally, photodegradation experiments using artificial doxycycline (DOX) water were conducted to determine the practical relevance of the research findings. In areas like antimicrobial applications and photodegradation of DOX, these extra experiments aimed to show the practical applicability and potential advantages of the research findings.

The wettability of the oil-brine-rock systems is very challenging mainly for the carbonate reservoirs and it plays a significant role to enhance the oil recovery (EOR). Carbonate rocks are mad-up of complex lithology, hence these requires careful treatments in controlling their wetting behavior for enhanced oil recovery. Therefore, it is extremely important to modify their wettability from an oil-wet rock behavior to a water-wet so that the residual oil can be produced efficiently. Thus, the present study has examined the effectiveness of alumina nanofluid as well as a new chemical methyl blue to alter the wettability. The methyl blue is released on massive scale from various industries i.e. pharma, textile and food industry which is a key environmental concern which contaminates the water table. Hence the study, explores the effects of MB and alumina nanofluid on the wettability. The effect of nanofluids formulated via dispersing the alumina nanoparticles in aqueous solutions at various concentration (0. 0.05, 0.3, 0.50, 0.75 and 1.0 wt. %) were tested for wettability modification under different physio-thermal conditions. Subsequently, the wettability change was examined for the samples treated with different concentrations of MB (10, 15, 30, 50 and 100 mg/L) for 7-days at two different temperatures of (25 and 50 0C). The results showed that hydrophobicity of the SML carbonate rock has significantly reversed while treating with alumina nanofluids and MB. Thus, the wettability modification/reversal via treatment of MB and alumina nanofluid can be an effective mechanism to hydrogen injection and for EOR processes.

In mobile applications such as geomagnetic surveying, two major effects hamper the use of optically pumped magnetometers: dead zones, sensor orientations where the sensors signal amplitude drops; and heading errors, a dependence of the measured magnetic field value on the sensor orientation. We present a concept for an omnidirectional magnetometer to overcome both these effects. The sensor uses two cesium vapor cells, interrogated by circularly-polarized amplitude-modulated laser light split into two beams running perpendicular to each other. This configuration is experimentally investigated using a setup wherein the laser beam and magnetic field direction can be freely adjusted relative to each other within a magnetically shielded environment. We demonstrate that a dead-zone free magnetometer can be realized with nearly isotropic magnetic-field sensitivity. While in the current configuration we observe heading errors emerging from light shifts and due to the nonlinear Zeeman effect, we introduce a straightforward approach to suppress these systematic effects in an advanced sensor realisation.

In the present study, the ability of novel carbon microspheres (CMs) derived from a date palm (Phoenix dactylifera) biomass using a hydrothermal carbonization (HTC) process and activated using phosphoric acid in removing methylene blue dye was investigated. Three types of palm-based wastes (seeds, leaflet and inedible crystallized date palm molasses) were used and converted to CMs via HTC process. The prepared samples were then activated using phosphoric acid via incipient wetness impregnation method. The CMs samples before and after activation were analyzed using scanning electron microscopy (SEM), elemental analysis and scanning (CHNS), Fourier Transform-Infrared (FTIR) and Brunauer–Emmet–Teller (BET) method. The samples exhibited high BET surface areas after activation (1,584 m2/g). The methylene blue adsorption results showed good fittings to the Langmuir and Redlich-Peterson isotherm models for all activated samples. The maximum adsorption capacity achieved was 409.84 mg/g for activated CM obtained from the palm date molasses, indicating high potential for application as dye-based adsorption materials.

This paper explores the challenges faced by blue-collared international migrants in adapting to new and unfamiliar climates while pursuing job opportunities, with a focus on poverty alleviation. Drawing on existing research and empirical evidence, the study investigates the trials encountered by these migrants as they navigate climate shocks and assesses the potential impacts on poverty reduction efforts. The findings underscore the significant difficulties blue-collared migrants experience when confronted with abrupt changes in climate conditions, adversely affecting their physical and mental well-being, as well as their employment prospects. The process of adjustment involves not only acclimating to new climate patterns but also navigating cultural nuances and social dynamics, exacerbating stress and feelings of isolation. Consequently, these challenges can perpetuate poverty by disrupting employment stability and limiting opportunities for career advancement. To address these issues, the paper proposes comprehensive support measures, including targeted pre-departure training programs, access to retraining opportunities, and assistance in securing sustainable livelihoods. By prioritizing climate resilience and empowering blue-collared migrants to adapt effectively to new climates, it becomes possible to enhance their livelihood prospects, reduce poverty levels, and foster sustainable development. The paper concludes by highlighting the significance of integrating climate adaptation strategies with poverty alleviation efforts to create a more inclusive and resilient future for blue-collared migrants in their pursuit of sustainable livelihoods.

Development of new neurotherapeutics is strongly depending on appropriate animal model chosen in preclinical studies. A cuprizone model is an effective tool for studying demyelination and re-myelination processes in the brain, but BBB integrity in cuprizone model is still a topic for debate. Several publications claim that BBB remains intact during cuprizone-induced demyelination; others demonstrate results that could be explained by the increased BBB permeability. In our work we aim to analyze permeability of BBB for different macromolecules, particularly, antibody-conjugates in cuprizone-intoxicated mice. We compared the traditional approach using Evans blue injection with following dye extraction and detection of antibody-conjugates using magnetic resonance imaging (MRI) and confocal microscopy to analyze BBB permeability in cuprizone model. First, we validated our model of demyelination by detecting changes in gene expression of myelin basic protein and proteolipid protein, and by performing MRI and histological analysis. Our results suggest that the methods with better sensitivity were able to detect the accumulation of macromolecules (such as fluorescent-labeled or gadolinium-labeled antibody conjugates) in the brain, suggesting a local BBB disruption in the demyelinating area. These findings support previous investigations that ques-tioned BBB integrity in cuprizone model and demonstrate possibility for delivery of anti-body-conjugates to demyelinated corpus callosum

Fit-for-purpose land administration (FFPLA) seeks to simplify cadastral mapping via lowering the costs and time associated with conventional surveying methods. The approach can be applied to both initial establishment and on-going maintenance of system. In Ethiopia, cadastral maintenance remains an on-going challenge, especially in rapidly urbanizing peri-urban areas, where farmers' land rights and tenure security are often jeopardized. Automatic Feature Extraction (AFE) is an emerging FFPLA approach, proposed as an alternative for mapping and updating cadastral boundaries. This study explores the role of the AFE approach for updating cadastral boundaries in the vibrant peri-urban areas of Addis Ababa. Open-source software solutions are utilized to assess the (semi-) automatic extraction of cadastral boundaries from orthophotos (segmentation), designation of 'boundary' and 'non-boundary' outlines (classification), and delimitation of cadastral boundaries (interactive delineation). Both qualitative and quantitative assessments of the achieved results (validation) are undertaken. A high-resolution orthophoto of the study area and a reference cadastral boundary shape file are used, respectively, for extracting the parcel boundaries and validating the interactive delineation results. Qualitative (visual) assessment verified the completed extraction of newly constructed cadastral boundaries in the study area, although non-boundary outlines such as footpaths and artefacts are also retrieved. For the buffer overlay analysis, the interactively delineated boundary lines and the reference cadastre were buffered within the spatial accuracy limits for urban and rural cadasters. As a result, the quantitative assessment delivered 52% correctness and 32% completeness for a buffer width of 0.4m and 0.6m, respectively, for the interactively delineated and reference boundaries. The study further demonstrated the potentially significant role AFE could assist in delivering fast, affordable, and reliable cadastral mapping. Further investigation, based on user input and expertise evaluation, could help to improve the approach and apply it to a real-world setting.

The coastal zone, situated at the sensitive interface between land and sea, serves as a pivotal area of extensive human economic activities. As one of China's economic special zones, Xiamen exemplifies the comprehensive trajectory of coastal governance in China. This research adopts an interdisciplinary approach grounded in historical geography and political ecology, employing data collection methods encompassing historical literature, field surveys, and interviews. The research findings indicate that:(1) The year 1994 witnessed the pivotal role played by the United Nations Convention on the Law of the Sea (UNCLOS) in connecting Jimei Peninsula from a local context to the international arena, thus signifying a momentous turning point in the process of scale reconstruction. However, the subsequent implementation of the Coastal Exclusion Policy in 2002 had detrimental consequences, leading to the disintegration of the local scale, the erosion of maritime culture, and the disregard for the livelihood security of displaced coastal populations.(2)The Coastal Exclusion Policy serves as an instrumental tool for implementing scale politics, while its functional realignment has had profound implications for the coastal zone, encompassing economic transformation, ecological degradation, and the marginalization of the socio-cultural fabric that intertwines humans and the coastal environment.

The objective of the current investigation is to identify the first or first draining node or sentinel lymph node (SLN) from the primary tumor mass in a regional lymphocenter. Four different indirect lymphography (IL) methods were employed in 96 canine patients with different types of cancer between 2018 and 2021. The IL technique involved intradermal, submucosal, and peritumoral injections of 2ml contrast agent in the four-quadrant principle which were divided into equal aliquots. Lymphatic mapping with lipiodol (iodized oil) was 100% in squamous cell carcinoma of the head and neck, anal sac apocrine gland adenocarcinoma, mast cell tumor, squamous cell carcinoma of the skin, mammary carcinoma, and with methylene blue dye, 100% detection was achieved in testicular tumor and mammary carcinoma. Instead of a very short washout time of 2 minutes, Iohexol showed an excellent detection in indirect CT lymphography for histiocytic sarcoma and in indirect radiographic lymphography for lymphosarcoma. The significance of contrast and blue dyes in detecting the lymphatic spread of canine cancers is clearly emphasized in the current investigation. The nature of cancerous tissue was again analyzed through image and machine learning approach in this work. Supervised machine learning technique is applied in this work for automatic classification of cancerous and non-cancerous regions. Various statistical and texture-based features are extracted from X-Ray images and support vector machine with linear, polynomial, multilayer perceptron (MLP), and RBF kernel functions are applied for classification. Highest 95.53%, 94.64%, 93.05% sensitivity, specificity, accuracy, respectively, is achieved using RBF kernel function.

Based on the eventual destruction of the solar system and the critical need for human continuation, this article suggests sending synthetic biology- and AI-created plant-like astronauts to the closest habitable exoplanet, Teegarden's Star b. Here we show that these astronauts will have green skin, blue blood, and the ability to perform photosynthesis. They could withstand cosmic radiation and extremely low temperatures in space while generating energy through photosynthesis. This groundbreaking interdisciplinary approach may provide a solution to the survival challenges faced by humans on their eternal interstellar journey. As long as plant-like astronauts possess human consciousness, it does not matter whether they are even a hybrid of carbon-based and silicon-based life. They will be a continuation of humanity on exoplanets. Human faces two options for survival. The first is the Mars migration program led by Elon Reeve Musk, which remains within the solar system and may not protect against the Sun's future scorching all life on the solar system during its red giant phase. The second option involves a more daring approach: the frantic escape of plant-like astronauts from the solar system. Should we consider both options simultaneously, much like how humans use their two legs to walk?

Simultaneous biofortification of vegetable crops with selenium and iodine is necessary in areas where there is a lack of these two elements. The main reason for lack of selenium and iodine in humans is inadequate intake of these two elements from vegetable crops. Biofortification through various agricultural methods including artificial lighting is a pragmatic way of increasing the concentration of these elements in plants. This research was conducted as a three-factor factorial experiment arranged as completely randomized pots replicated thrice in the greenhouse during year 2022. Three levels of sodium selenate fertilizer (S1: 0, S2: 2, S3: 4 mg/l), three levels of potassium iodate (I1: 0, I2: 2, I3: 4 mg/L) and two additional blue light radiation levels (L1: radiation and L2: no blue light radiation) were applied and data was measured at two growth stages namely 40 and 80-days. The results showed that the highest (11.44 g) and the lowest (9.55 g) shoot dry weight values at the 40-day-stage were observed in the supplementary blue light and sunlight (control), respectively. Moreover,, under complementary blue light conditions, the highest and the lowest (5.85 and 3.38 mg/g leaf fresh weight) of leaf chlorophyll value at the 40-day-stage were recorded at sodium selenate 4 and 0 mg/l, respectively. The highest and the lowest (5.24 and 4.76 mg/g) fresh weight of leaf anthocyanin at the 40-day-growth stage were related to supplementary blue light and sunlight treatment (control), respectively. Under the supplementary blue light and 0 mg/l of selenium , the highest and the lowest value of shoot trigonelline (102.56 and 72.14 mg/100 g fresh weight) were obtained at 4 and 2 mg/L of iodine, respectively. Furthermore, in the same treatment, the highest and the lowest of seed trigonelline amounts (0.99 and 0.74 mg/g dry weight) corresponded with 4 and 0 mg/l of iodine, respectively.

The advent of the digital age has brought about significant transformations in the entertainment industry, challenging traditional paradigms and redefining the ways in which content is created, distributed, and consumed. This research paper critically reviews the paradigm shift occurring in the entertainment industry, focusing on the implications of digital technologies, the rise of online platforms, changing consumer behavior, and the impact on various stakeholders. By analyzing relevant literature, industry reports, and case studies, this paper aims to comprehensively understand the challenges and opportunities presented by the digital age and assess its impact on the entertainment industry.

Mangrove creeks adjoining typical riverine mangrove forests is known to be a net source of CO2 and dissolved inorganic carbon (DIC) to the ocean due to the decomposition of rich organic carbon in the soil; such information is limited in fringe mangroves. This study aims to clarify the difference in carbonate processes between the two types of mangrove forests. We conducted continuous monitoring of the partial pressure of carbon dioxide (pCO2) and measured carbonate chemistry parameters (total alkalinity (TA) and DIC) in two types of mangrove areas located in Okinawa, Japan. The result showed that the maximum pCO2 reached 5242 µatm in the Fukido River estuary (a riverine mangrove), whereas it was only 765 µatm on the Yubu coast (a fringe mangrove). The measured maximum TA and DIC values were 3285 µM and 3283 µM in the Fukido River estuary and 3162 µM and 2977 µM on the Yubu coast. These indicate that pCO2 on the Yubu coast was maintained at low values by the carbonate buffering capacity even when TA and DIC increased rapidly. The mangroves on the Yubu coast grow on dead corals and coral soils. It was suggested that the DIC/TA ratio was constantly kept at approximately 0.9 due to TA production by the dissolution of calcium carbonate (CaCO3), which resulted in lower pCO2.

In this work, a high throughput nanozymatic method was developed for green nanozyme-mediated biodegradation of organic dyes in real water media. The nanozymes were synthesized and characterized for their size and morphology by TEM and DLS analysis. The nanozymatic properties of the as-prepared nanomaterials were evaluated by standard enzyme activity assay, revealing high peroxidase-like performances for the as-prepared nanozymes. Therefore, for exploring more precise, the kinetics behavior of the as-prepared nanozymes was evaluated by the standard Lineweaver-Burk method, revealing a V_max as high as 0.263 µM sec^-1 and a K_m as low as 0.03 mM, revealing high catalytic efficiency and affinity of the as-prepared nanozymes. Hence, the as-prepared nanozymes were utilized for organic dye degradation in real water media using methylene blue as a model organic dye. The effective factors on the dye degradation including pH, ionic strength, degradation time, nanozyme amount, etc. were optimized by the one-factor-at-a-time optimization method. At optimal experimental conditions, the as-prepared nanozymes can degrade about 99.0% of the organic dye within a degradation time as low as 7 min. The developed method was finally employed for the nanozyme-mediated degradation of methylene blue from real water media such as pool, mineral, river, and tap water samples. The results of this study revealed an excellent biodegradation yield of over 94.3%-99.0% for the different real samples, proving the suitability of the developed method for dye degradation in real water media.

Technological defects in the organoleptic characteristics of cheese (odour, colour, texture and flavour) reduce quality and consumer acceptance. A red colour defect in Cabrales cheese (a traditional, blue-veined, Spanish cheese made from raw milk) occurs infrequently but can have a notable economic impact on family-owned, artisanal cheesemaking businesses. This work reports the culture-based determination of Serratia marcescens strain R01 as the microbe involved in the appearance of red spots on the surface and nearby inner areas of such cheese. Sequencing and analysis of its genome revealed a cluster of 16 genes involved in the production of prodigiosin, a tripyrrole red pigment. HPLC analysis confirmed the presence of prodigiosin in methanol extracts of S. marcescens RO1 cultures. The same was also observed in extracts from red areas of affected cheeses. The strain showed low survival rates under acidic conditions, but was not affected by concentrations of up to 5% NaCl (the usual value for blue cheese). The optimal conditions for prodigiosin production by S. marscescens RO1 on agar plates were 32 ºC and aerobic conditions. Prodigiosin has been reported to possess antimicrobial activity, which agrees with the here-observed inhibitory effect of RO1 supernatants on different bacteria, its inhibition of Enterobacteriaceae, and the delayed development of Penicillium roqueforti during cheesemaking. The association between S. marcescens and the red colour defect was strengthened by recreating the fault in experimental cheeses inoculated with RO1. The data gathered in this study points towards the starting milk to be the origin of this bacterium in cheese. These findings should help in the development of strategies that minimize the incidence of pigmenting S. marcescens in milk, the red defect the bacterium causes in cheese, and its associated economic losses.

The article proposes a method for determining the p-value of correlations in compositional data, i.e., those data that arise as a result of dividing the original values by their sum. Data organized in this way are typical for many fields of knowledge, but there is still no consensus on methods for interpreting correlations in such data. In a space closed by normalizing quantity, correlation coefficients behave differently than under normal conditions: their probabilities of occurrence do not coincide with those inherent in the standard scale of estimates. In the tens of the new millennium, almost all newly emerging methods for estimating correlation in compositional data began to require mandatory log-transformation of the variable values. In the method proposed here there are no log-transformations. We return to the early stages of attempting to solve the problem and rely on negative shifts in correlations in the multinomial distribution. In modeling the data, we use a hybrid method that combines the hypergeometric distribution with the distribution of any other law. During our work on the calculation method, we found that the number of degrees of freedom in compositional data measures discretely only when all the normalizing sums are equal and that it decreases when the sums are not equal, becoming a continuously varying quantity. Estimation of the number of degrees of freedom and the strength of its influence on the magnitude of the shift in the distribution of correlation coefficients is the basis of the proposed method.

The methylene blue (MB) adsorption was performed on a natural material powder of Cynarascolymus as identified by Cs. To analyze the Cs material, FTIR, SEM, isoelectric point (pHpzc) analysis, TGA, and DRX were used. The maximum experimental adsorption capacity of the Cs material was 203.333, 192.187, and 179,380 mg•g-1 at 298, 303, and 313 K, respectively. The correlation coefficients (R2) and average percentage errors APE(%) values for the kinetic and isotherms models indicated that the adsorption kinetics fol-lowed a pseudo-nth order model and that the Traditional isotherm model Red-lich-Peterson (R-P) correctly described the experimental data obtained at 298, 303, and 313 K, respectively. The steric, energetic, and thermodynamic characteristics of the most rele-vant advanced model (double-energy single-layer model (AM 2)) were analyzed in detail. The number of active sites for the first receptors (n1) was determined to be 0.129, 0.610, and 6.833; whereas the number of second active sites (n2) was determined to be 1.444, 1.675, and 2.036 at 298, 303, and 313 K, respectively. This indicated the presence of both multi–docking and multimolecular modes for the first style of MB ions (n1); while only a multi-molecular mode for the second style of MB ions (n2). Thermodynamic characteristics demonstrated that MB adsorption onto the Cs adsorbent is spontaneous and feasible.

Medium polarity plays a crucial role in charge-transfer processes and electrochemistry. The added supporting electrolyte in electrochemical setups, essential for attaining the needed electrical conductivity, sets challenges for estimating medium polarity. Herein, we resort to Lippert–Mataga–Ooshika (LMO) formalism for estimating the Onsager polarity of electrolyte organic solutions pertinent to electrochemical analysis. An amine derivative of 1,8-naphthalimide proves to be an appropriate photoprobe for LMO analysis. An increase in electrolyte concentration enhances the polarity of the solutions. This effect becomes especially pronounced for low-polarity solvents. Measured refractive indexes provide a means for converting Onsager to Born polarity, which is essential for analyzing medium effects on electrochemical trends. This study demonstrates a robust optical means, encompassing steady-state spectroscopy and refractometry, for characterizing solution properties important for charge-transfer science and electrochemistry.

Quartz Crystal Microbalance (QCM) is a well-known method to measure the mass of ligands bound to receptor-covered surfaces in various fields, ranging from materials science to biology. Actin molecule is essential in various cellular processes through its function of monomer-to-filament polymerization, forming a double-stranded filament with a 75 nm pitch. In this study, QCM was applied to measure the physical properties of actin, finding that the frequency shifted negatively when monomeric actin bound to the QCM surface, whereas the frequency shifted positively when filaments bound. Using fluorescence light microscopic observations, we have examined whether negative and positive frequency shifts originated from their length. In order to control this process, a severing protein, fragmin was used to change the length of actin filament. When the average length of filaments shortened, the magnitude of positive shift decreased in a concentration-dependent manner. However, shorter filaments showed a negative frequency shift depending on their concentration, showing that the weight derived from the loaded concentration and the function derived from actin polymerization dynamics are detectable. Interestingly, the transition from positive to negative occurred when the average length of actin was ~33 nm, or approximately equal to the half-pitch of filaments. Thus, actin filaments can serve as an excellent standard to measure the mechanical properties of biopolymers. Our results show that the QCM sensor could be both a "weight" and a "function" sensor of biomolecules in vitro.

Appropriate governance structures are extremely important for the fishery dependent communities to develop integrated territorial development strategies and adaptive capacity to change, including the climate one. This paper assesses to what extent fisheries co-management schemes (e.g Fisheries LAGs, being regional/local governance instruments in fishing communities) are strengthening sustainability. The latter includes improving energy efficiency, promoting renewable energy sources (RES), coping with climate crisis, minimizing environmental impacts, and promoting sustainable blue economy. For detecting policy aspects of aligning climate neutrality and sustainable blue economy, the research lens focuses on the Greek Fisheries Local Action Groups (FLAGs) given that these are mostly located in coastal/marine and insular territories with significant blue growth potential. To map and assess their capacity and efficiency in pursuing Green Deal objectives, a co-development process with FLAG managers was put in place. The results and findings of this process reveal the scarcity of sustainability and blue economy related strategies. Key conclusion is that transition to a post-carbon blue economy on a local level, requires the understanding of the evolutionary dynamics of fisheries co-management schemes. The latter, being multi-sectoral structures, may boost dialogue and cooperation to harmonize local development strategies and EU policies. Maritime Spatial Planning (MSP) as an evolutionary governance process itself, can be a driver for making FLAGs evolve, and strengthen commonization and blue justice and equity for fishers.

Underwater wireless optical communication (UWOC) is acknowledged as a useful way to transmit data in ocean for short distance application. Carrying UWOC device on mobile platform is quite practical in ocean engineering, which is helpful to exploit its advantages. In application, such platform needs camera to observe surroundings and guide its action. Since the majority of ocean is always dark, active illumination is necessary to imaging. Once UWOC worked in such environment, its performance is affected by the illumination light noise. In this paper, we study the influence of underwater LED illumination on bidirectional UWOC with Monte Carlo method. We simulate forward noise from the LED illumination to the opposite receiver in the cooperative terminal, and the backscattering noise on the adjacent receiver in the same terminal. The results show that the forward noise is reduced with the increase of absorption coefficient, scattering coefficient, transmitting distance, and separated distance between receiver and the optical axis of LED. But it becomes greater with FOV of receiver. The backscattering noise is reduced with the increase of absorption coefficient and separated distance between receiver and LED. But it becomes greater with FOV and scattering coefficient, while it has little relation with transmitting distance. In order to reduce such two kind noises, besides inserting optical filter in the receivers and narrow their field, the optical axis of LED light should keep away from the receivers. The results in this paper is helpful for UWOC application.

We investigated and quantified soil organic carbon (SOC) stock at the mangrove forest (Magyi, That Bot Khan and Wette) of Shwe Thaung Yan coastal region in Myanmar and estimated the SOC stock changes in Magyi mangrove forest over six years using repeated field measurements. The study sites were characterized by different mangrove vegetation, soil types, and sediment deposition from different water sources. Results showed that the mangrove preservation and restoration efforts had a significant effect on soil C storage, with soil carbon stocks in 2021 (1954.43 ± 33.24 ton/ha) being 2.7 times higher than the estimated carbon stock in 2015 (732.26 ± 6.99 ton/ha). The results also revealed slight differences in SOC between Magyi and the Tha-Bot-Khan and Wette areas, as the mangrove plants in the latter areas have an additional source of nutrients from Pho-Thoung-Gyi, a deep-sea bay near the forest. Our research findings are beneficial in understanding the role of Myanmar’s mangrove ecosystems in carbon sequestration and climate change mitigation efforts.

The few studies dealing with leaf phenological responses to elevated nutrients in forest trees have given ambiguous results, i.e., while some reported delayed leaf-out and autumn leaf senescence, others reported advanced leaf phenology caused by increased nutrition. This study aimed to determine the effects of experimentally increased phosphorus (+P) on the leaf phenologies of two juvenile provenances of common beech and sessile oak. Other objectives were to determine whether there are interspecies differences as well as intraspecies variations. Saplings were excavated in two mixed beech-oak stands and transplanted into four wooden boxes filled with a commercial soil substrate. Phosphorus fertilizer was added to two of the boxes, while the remaining boxes served as controls. Both species responded to +P treatment with advanced autumn leaf senescence in the first year of the experiment. Leaf senescence in common beech began significantly earlier, while in both species, the process was accelerated compared to that in the control. In the second year, the leaf senescence response to +P treatment was even more pronounced in both species. The +P effect on leafing phenology was absent in both common beech provenances and in an oak provenance. However, the other oak provenance showed advanced leafing, indicating the existence of intraspecies differences.

Increased screen time during the COVID-19 pandemic and the accelerated incorporation of technology into daily practices have directly contributed to the increased prevalence of eye disease. The human eye is not built for continual technological use and must adjust to exposure to digital screens. Overexposure to technology can result in eye strain and an increased risk of eye diseases such as myopia with complications later in life, including retinal tears, cataracts, and macular degeneration. As vision and ocular diseases become more prevalent, the study of eye diseases, including their causes and treatments, is especially relevant. There is a need to prevent ocular diseases before they become a burden to individuals, their families, and their communities by better understanding the pathophysiology of ocular diseases. Several ocular diseases are thought to be caused by imbalances in reactive oxygen species (ROS) and autophagy. ROS refers to a class of highly reactive oxygen-containing molecules that can undergo damaging reactions with other molecules in the cell. Autophagy is a cellular process of self-eating whereby damaged, harmful, or dead material in cells is broken down to maintain cellular homeostasis. This paper discusses the role of ROS and autophagy in the pathogenesis of computer vision syndrome (CVS), digital eye strain (DES), myopia, cataracts, glaucoma, diabetic retinopathy (DR), age-related macular degeneration (AMD), optic nerve crush injury (OCN), optic nerve gliomas, and retinoblastoma. Lifestyle changes such as limiting screen time, ensuring adequate exposure to evening sunlight, and using blue light protection measures or protective eyewear are important in the prevention of eye disease. Nutrition also contributes significantly to eye health. A balanced diet rich in vitamins and antioxidants may help to prevent ROS and autophagy imbalance-induced eye disease. Medical and surgical treatments become necessary when preventative measures fail. This paper also addresses how government measures to decrease the onset of eye disease, including targeted programs to increase access to fresh vegetables and fruits in food deserts, are a critical macro-level avenue to reduce eye disease prevalence in the US, which according to the National Eye Institute, costs $139 billion yearly.

Music-domain visual programming languages (VPLs) have shown to be Turing complete. However, the common lack of built-in flow control structures can obstruct using VPLs implementing general-purpose algorithms, which harms the direct use of algorithms and algorithm theory in art creation processes using VPLs. In this article, we show how to systematically implement general-purpose algorithms in music-domain visual languages by using the Finite State Machines with Datapath computation model. The results expose a finite state machine and a set of internal state variables that walk paths whose speed can be controlled using a metronome ticks and whose path depends on the initial conditions of the algorithm. These elements can be further mapped to music elements according to the musician's intentions. We demonstrate this technique by implementing Euclid's Greatest Common Divider algorithm and using it to control high-level music elements in an implementation of Terry Riley's In C, and to control audio synthesis parameters in a FM synthesizer.

Due to its high specific surface area and rich porous structure, acacia-derived porous activated carbon is the most potentially effective material for wastewater treatment. This research study aimed to prepare activated carbon using Acacia erioloba seedpods as carbonaceous materials and phosphoric acid as an activating agent. The specific surface area of the prepared activated carbon sample was characterised by Brunauer–Emmett–Teller instrument. The specific surface area value was 387 m²/g. The activated carbon prepared was then sieved into three different particle sizes of 50, 100 and 200 micrometres and characterised using various analytical procedures, including proximate analysis to study moisture content, ash content, volatile matter content and fixed carbon content. The bulk density, SEM, power of hydrogen, iodine number and methylene blue number index were also investigated to determine the adsorption properties of the prepared activated carbon. Batch adsorption dynamics for the removal of organic compounds such as methylene blue and unsaturated character of fatty acid from aqueous solution were also carried out at room temperature to evaluate the prepared activated carbon's applicability in water treatment. The iodine number was 528, 638, and 554 mg/g for the 50, 100, and 200 μm activated carbon particles, respectively. From the results, the adsorption of methylene blue favoured the Freundlich adsorption model, showing higher correlation (R²) values than the Langmuir model. The results indicate that methylene blue particles were adsorbed on heterogeneous surfaces.

This paper presents a novel approach for accurate counting and localization of tropical plants in aerial images that is able to work in new visual domains in which the available data is not labeled. Our approach uses deep learning and domain adaptation, designed to handle domain shift between the training and test data, which is a common challenge in this agricultural applications. This method uses a source dataset with annotated plants and a target dataset without annotations, and adapts a model trained on the source dataset to the target dataset using unsupervised domain alignment and pseudolabeling. The experimental results show the effectiveness of this approach for plant counting in aerial images of pineapples under significative domain shift, achieving a reduction up to 97% in the counting error when compared to the supervised baseline.

A novel scheme that can simultaneously measure the Doppler frequency shift (DFS) and angle of arrival (AOA) of microwave signals is proposed. At the signal receiving unit (SRU), two echo signals and the reference signal are modulated by a Sagnac loop structure and sent to the central station (CS) for processing. At the CS, two low-frequency electrical signals are generated after polarization control and photoelectric conversion. The DFS without direction ambiguity and wide AOA measurement can be real-time acquired by monitoring the frequency and power of the two low-frequency electrical signals. In the simulation, an unambiguous DFS measurement with errors of ±3×10-3 Hz and a -90° to 90° AOA measurement range with errors of less than ±0.5° are realized. The safety and robustness of the system to environmental disturbance are improved, and it is more suitable for the modern electronic warfare system.

Resolving small molecule mixtures by nuclear magnetic resonance (NMR) spectroscopy has been of great interest for a long time for its precision, reproducibility and efficiency. However, spectral analyses for such mixtures are often highly challenging due to overlapping resonance lines and limited chemical shift windows. The existing experimental and theoretical methods to produce shift NMR spectra in dealing with the problem have limited applicability owing to sensitivity issues, inconsistency and / or requirement of prior knowledge. Recently, we have resolved the problem by decoupling multiplet structures in NMR spectra by the wavelet packet transform (WPT) technique. In this work, we developed a scheme for deploying the method in generating highly resolved WPT NMR spectra and predicting the composition of the corresponding molecular mixtures from their 1H NMR spectra in an automated fashion. The four-step spectral analysis scheme consists of calculating WPT spectrum, peak matching with a WPT shift NMR library, followed by two optimization steps in producing the predicted molecular composition of a mixture. The robustness of the method was tested on an augmented dataset of 1000 molecular mixtures, each containing 3 to 7 molecules. The method successfully predicted the constituent molecules with a median true positive rate of 1.0 against the varying compositions, while a median false positive rate of 0.04 was obtained. The approach can be scaled easily for much larger datasets.

Electron can tunnel between cofactor molecules positioned along biological electron transport chains up to the distance of ≃20 Å on the millisecond time scale of enzymatic turnover. This tunneling range mostly determines the design of biological energy chains facilitating cross-membrane transport of electrons. Tunneling distance and cofactors’ redox potentials become main physical parameters of this design. The protein identity, flexibility, or dynamics are missing from this picture assigning universal charge-transport properties to all proteins. This paradigm is challenged by dynamical models of electron transfer showing that the hopping rate is constant within the crossover distance R*≃12 Å, followed with an exponential tunneling falloff at longer distances. In this view, energy chains for electron transport are best designed by placing redox cofactors near the crossover distance R*. Protein flexibility and dynamics affect the magnitude of the maximum hopping rate within the crossover radius. Protein charge transport is not driven by universal parameters anymore and protein identity matters.