Search | Preprints.org

Preprint REVIEW | doi:10.20944/preprints202104.0361.v1

Guideline on Returning to Work after COVID-19 Infection

Mikhael Yosia, Nuri Purwito Adi

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: COVID-19; occupational health; new normal

Online: 13 April 2021 (14:33:45 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202207.0160.v2

NIH SenNet Consortium: Mapping Senescent Cells in the Human Body to Understand Health and Disease

Patty J Lee, Philip Blood, Katy Börner, Judith Campisi, Feng Chen, Heike Daldrup-Link, Phil De Jager, Li Ding, Francesca E. Duncan, Oliver Eickelberg, Rong Fan, Toren Finkel, Vesna Garovic, Nils Gehlenborg, Carolyn Glass, Ziv Bar-Joseph, Pragati Katiyar, So-Jin Kim, Melanie Königshoff, George Kuchel, Haesung Lee, Jun H. Lee, Jian Ma, Qin Ma, Simon Melov, Kay Metis, Ana L. Mora, Nicolas Musi, Nicola Neretti, João F. Passos, Irfan Rahman, Juan Carlos Rivera-Mulia, Paul Robson, Mauricio Rojas, Ananda L. Roy, Birgit Schilling, Pixu Shi, Jonathan Silverstein, Vidyani Suryadevera, Jichun Xie, Jinhua Wang, An-Kwok Ian Wong, Laura Niedernhofer

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Cellular Senescence Network; Normal Aging; Senescence; Senescence-associated secretory phenotype; SenNet

Online: 15 September 2022 (12:52:05 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202102.0359.v2

Factors Affecting Customer Satisfaction & Loyalty in Online Food Delivery Service during COVID-19 Pandemic: Its Relation with Open Innovation

Yogi Tri Prasetyo, Hans Tanto, Martinus Mariyanto, Christopher Hanjaya, Michael Nayat Young, Satria Fadil Persada, Bobby Ardiansyah Miraja, A.A.N. Perwira Redi

Subject: Engineering, Automotive Engineering Keywords: food delivery; customer satisfaction; new normal; COVID-19; theory of planned behavior

Online: 19 February 2021 (10:01:10 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201607.0069.v1

Testing Ststistical Hypothesis in Light of Mathematical Aspects in Analysis of Probability

Michael Fundator

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Principal of prediction; random sequences; recurrence; Law of Large Numbers; exponential; normal; bivariate; distribution; Entropy; Information

Online: 23 July 2016 (09:25:13 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201611.0121.v1

Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery

Marieke A. Stammes, Hendrica A. J. M. Prevoo, Meyke C. Ter Horst, Stéphanie A. Groot, Cornelis J. H. Van De Velde, Alan B. Chan, Lioe-Fee De Geus-Oei, Peter J. K. Kuppen, Alexander L. Vahrmeijer, Elena B. Pasquale, Cornelis F. M. Sier

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: tissue microarray; immunohistochemistry; cancer imaging; tyrosine kinase receptor; normal tissue; colon cancer

Online: 24 November 2016 (11:07:23 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201705.0043.v1

Bayesian Hierarchical Scale Mixtures of Log-Normal Models for Inference in Reliability with Stochastic Constraint

Hea-Jung Kim

Subject: Computer Science And Mathematics, Information Systems Keywords: Bayesian reliability analysis; Bayesian hierarchical model; MCMC method; scale mixtures of log-normal failure time model; stochastic constraint; two-stage MaxEnt prior.

Online: 4 May 2017 (16:26:10 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201709.0166.v1

Alzheimer's Disease, Brain Injury, and C.N.S. Nanotherapy in Humans: Sonoporation Augmenting Drug Targeting

Joseph S. D'Arrigo

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Alzheimer's disease; drug targeting; nanoemulsion; neuroinflammation; neurotrauma; oxidative stress; scavenger receptors; SR-BI; transcranial sonoporation

Online: 30 September 2017 (05:21:37 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201804.0377.v1

Land Cover Change Detection Based on Adaptive Contextual Information Using Bi-Temporal Remote Sensing Images

Zhiyong Lv, Tongfei Liu, Penglin Zhang, Jón Atli Benediktsson, Yixiang Chen

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: land cover change detection; adaptive contextual information; bi-temporal remote sensing images

Online: 29 April 2018 (10:52:26 CEST)

Show abstract| Download PDF| Share

Preprint TECHNICAL NOTE | doi:10.20944/preprints202009.0683.v1

A Novel DNA Extraction Protocol from Frozen Blood of Normal Individuals and Patients Who Received Systemic Chemotherapy

Hayder O. Hashim, Mohammed Baqur S. Al-Shuhaib

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: DNA extraction; normal; patients; protocol; frozen blood

Online: 28 September 2020 (10:52:59 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202106.0089.v1

TSO-DSO Coordination Schemes to Facilitate Distributed Resources Integration

Fatemeh Najibi, Dimitra Apostolopoulou, Eduardo Alonso

Subject: Engineering, Energy And Fuel Technology Keywords: TSO-DSO coordination; Pareto front; Bi-level optimisation; Optimal power flow

Online: 2 June 2021 (15:53:22 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201909.0091.v1

Fisetin a 3, 7, 3′, 4′-Tetrahydroxyflavone Inhibits PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models

Jean Christopher Chamcheu, Stephane Esnault, Vaqar M. Adhami, Andrea L. Noll, Sergette Banang-Mbeumi, Tithi Roy, Sitanshu S. Singh, Shile Huang, Konstantin Gus Kousoulas, Hasan Mukhtar

Subject: Medicine And Pharmacology, Dermatology Keywords: fisetin; psoriasis; normal human epidermal keratinocyte; cell signaling; cell differentiation; proliferation; inflammatory cytokine; PBMC; CD4+ T lymphocyte; 3D psoriasis-like skin disease model

Online: 9 September 2019 (07:48:26 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Psoriasis is a chronic immune-mediated skin disease that involves interaction of both immune and skin cells, and is characterized by cytokine-driven epidermal hyperplasia, deviant differentiation, inflammation and angiogenesis. Because available treatments for psoriasis have significant limitations, dietary products are potential natural sources of therapeutic molecules, which can rescind molecular defects associated with psoriasis and could be developed for its management. Fisetin (3,7,3′,4′- tetrahydroxyflavone), a phytochemical naturally found in pigmented fruits and vegetables has demonstrated pro-apoptotic and antioxidant effects in several malignancies. This study utilized biochemical, cellular, pharmacological and tissue-engineering tools to characterize the effects of fisetin on normal human epidermal keratinocytes (NHEKs), peripheral blood mononuclear cells (PBMC) and CD4+ T lymphocytes in 2D and 3D psoriasis-like disease models. Fisetin treatment of NHEKs dose and time-dependently induced differentiation and inhibited interleukin-22-induced proliferation, as well as activation of the PI3K/Akt/mTOR pathway. Fisetin treatment of TNF-α-stimulated NHEKs significantly inhibited the activation of p38 and JNK, but had no effect on ERK1/2. In addition, fisetin treatment significantly decreased the secretion of Th1/Th-17 pro-inflammatory cytokines, particularly IFNγ and IL-17A by 12-O- tetradecanolylphorbol 13-acetate (TPA)-stimulated NHEKs and anti-CD3/CD28-activated human PBMCs. Furthermore, we established the in-vivo relevance of fisetin functions, using a 3D full-thickness human skin model of psoriasis (FTRHSP) that closely mimics in-vivo human psoriatic skin-lesions. Herein, fisetin significantly ameliorated psoriasis-like disease features, and decreased the production of IL-17 by CD4+ T lymphocytes co-cultured with FTRHSP. Collectively, our data identify pro-differentiative, anti-proliferative and anti-inflammatory effects of fisetin, via modulation of PI3K-Akt-mTOR and p38/JNK pathways and the production of cytokines in 2D and 3D human skin model of psoriasis. These results suggest that fisetin has a great potential to be developed as an effective and inexpensive agent for the treatment of psoriasis and other related inflammatory skin disorders.

Preprint ARTICLE | doi:10.20944/preprints201710.0120.v1

Normal Approximations of the Arithmetic of Mixed Fuzzy Numbers

Yi-Fang Chen, Hui-Chin Tang

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: fuzzy number; normal fuzzy number; addition and subtraction; approximation.

Online: 17 October 2017 (14:24:15 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201803.0084.v1

Estimation of Missing Streamflow Data Using Anfis Models and Determination of the Number of Datasets for Anfis: The Case of Yeşilırmak River

Kemal Saplioglu, Tulay Sugra Kucukerdem

Subject: Engineering, Civil Engineering Keywords: anfis; missing data; multiple regression; normal ratio method; Yeşilırmak

Online: 12 March 2018 (07:00:46 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201806.0148.v1

Normal Calculus on Moving Surfaces

Keith C. Afas

Subject: Computer Science And Mathematics, Mathematics Keywords: calculus of moving surfaces; CMS; differential geometry; normal; tensor; hypersurfaces; dynamic

Online: 11 June 2018 (09:54:25 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201711.0103.v1

Constraining Forces Stabilizing Superconductivity in Bismuth

Ekkehard Krüger

Subject: Physical Sciences, Condensed Matter Physics Keywords: superconductivity; bismuth at ambient pressure; Bi–I; bismuth at high pressure; Bi–V; constraining forces; nonadiabatic Heisenberg model

Online: 16 November 2017 (04:58:52 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201807.0009.v1

NiFeO_Xas a Bifunctional Electrocatalyst for Oxygen Reduction (OR) and Evolution (OE) Reaction in Alkaline Media

Alagar Raj Paulraj, Yohannes Kiros, Mats Ahmadi Götelid, Malin B. Johansson

Subject: Chemistry And Materials Science, Electrochemistry Keywords: Bi-functional catalyst; hydrothermal synthesis; OER/ORR; nickel ferrite; Ni FeLDH

Online: 2 July 2018 (10:47:25 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202106.0416.v1

An Observation on Distribution of Prime Numbers

Dariush Bahrami

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: Prime Number; Prime Numbers Distribution; Prime Number Generation; Normal Distribution

Online: 15 June 2021 (15:58:34 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201909.0088.v1

Distributed Generation Planning in Active Distribution Networks Based on Multi-Scene Analysis

Sitong Lv, Jianguo Li, Yongxin Guo, Zhong Shi

Subject: Engineering, Electrical And Electronic Engineering Keywords: active distribution network; distributed generation; multi-scene analysis; Scene reduction; improved clustering algorithm; bi-level programming; comprehensive security index

Online: 8 September 2019 (16:28:28 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201802.0041.v1

Solving Fuzzy Bi-matrix Games Through a Interval Value Function Approach

Kaisheng Liu, Yumei Xing

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: fuzzy bi-matrix game; equilibrium solution; non-linear optimization problem

Online: 5 February 2018 (15:44:19 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201905.0065.v1

Social-Ecological Experiments to Foster Agroecological Transition

Sabrina Gaba, Vincent Bretagnolle

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: agroecology; biodiversity; ecosystem services; post-normal science; socio-ecological systems; sustainability; stakeholders

Online: 6 May 2019 (12:28:18 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201912.0259.v1

Investigation of Propane and n- butane Hydrate Formation Condition and Determination of Equilibrium Pressure

Somayeh Salehfekr, Sajjad Porgar, Nejat Rahmanian

Subject: Physical Sciences, Chemical Physics Keywords: hydrate; propane; normal butane; equilibrium pressure

Online: 19 December 2019 (13:10:12 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202107.0666.v1

A Re-Evaluation of the Swiss Hail Suppression Experiment using Permutation Techniques shows Enhancement of Hail Energies when Seeding

Armin Auf der Maur, Urs Germann

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: hail prevention; non-normal distributions; permutation; bootstrap; confidence intervals

Online: 29 July 2021 (14:21:23 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201805.0296.v1

Some Normal Intuitionistic Fuzzy Heronian Mean Operators Using Hamacher Operation and Their Application

Guofang Zhang, Zhiming Zhang, Hang Kong

Subject: Computer Science And Mathematics, Computer Science Keywords: normal intuitionistic fuzzy numbers; Heronian mean; Hamacher t-conorm; Hamacher t-norm

Online: 22 May 2018 (10:15:21 CEST)

Show abstract| Download PDF| Share

Hamacher operation which is generalization of the Algebraic and Einstein operation, can widely provide a large number of arithmetical operation with respect to uncertainty information, and Heronian mean can deal with correlations of the input arguments or different criteria and don’t make calculation redundancy, meanwhile, the normal intuitionistic fuzzy numbers (NIFNs) can depict distinctively normal distribution information in practical decision making. In this paper, a multi-criteria group decision-making (MCGDM) problem is researched under the NIFNs environment, and a new MCGDM approach is introduced on the basis of the Hamacher operation. Firstly, according to Hamacher t-conorm and t-norm, some operational laws of NIFNs are presented. Secondly, it is noticed that Heronian mean can’t only once take into account mutual relation between attribute values once, but also consider the correlation between input argument and itself. Therefore, we develop some operators and study their properties in order to aggregate normal intuitionistic fuzzy numbers information, these operators include Hamacher Heronian mean (NIFHHM), Hamacher weighted Heronian mean (NIFHWHM), Hamacher geometric Heronian mean (NIFHGHM) and Hamacher weighted geometric Heronian mean (NIFHWGHM). Furthermore, we apply the proposed operators to the MCGDM problem and present a new method. The main characteristics of this new method involve that: (1) it is suitable to make decision under the normal intuitionistic fuzzy numbers environment and more reliable and reasonable to aggregate the normal distribution information. (2) it utilizes Hamacher operation which can provide more reliable and flexible decision-making results and offer an effective and powerful mathematic tool for the MAGDM under uncertainty. (3) it uses the Heronian mean operator which can considers relationships between the input arguments or the attributes and don’t brings subsequently about redundancy. Lastly, an application is given for showing the feasibility and effectiveness of the presented method in this paper.

Preprint REVIEW | doi:10.20944/preprints201802.0190.v1

Targeting Early Dementia: Using Lipid Cubic-Phase Nanocarriers to Cross the Blood-Brain Barrier

Joseph S. D'Arrigo

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Alzheimer’s disease; biomimetic nanocarriers; blood-brain barrier; dementia; drug targeting; lipid cubic phases; nanoemulsion; SR-BI; scavenger receptors

Online: 28 February 2018 (07:49:13 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202104.0532.v3

Examining the Role of the Noradrenergic Locus Coeruleus for 2 Predicting Attention and Brain Maintenance in Healthy Old Age 3 and Disease: An MRI Structural Study for the Alzheimer’s Disease 4 Neuroimaging Initiative

Emanuele Raffaele Giuliano Plini, Erik O'Hanlon, Rory Boyle, Francesca Sibilia, Gaia Rikhye, Joanne Kenney, Robert Whelan, Michael Christopher Melnychuk, Ian Hamilton Robertson, Paul Michael Dockree

Subject: Social Sciences, Psychology Keywords: Locus Coeruleus; Reserve; Brain Age; Visual Attention; Alzheimer’s Disease; Mild Cognitive Impairment; normal Aging; Neuroimaging; Voxel Based Morphometry

Online: 21 June 2021 (11:41:40 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201904.0006.v1

Facile Synthesis of Di-Mannitol Adipate Ester-Based Zinc Metal Alkoxide As Bi-Functional Additives for PVC

Yuepeng Li, Degang Li, Wenyuan Han, Manqi Zhang, Bing Ai, Lipeng Zhang, Hongqi Sun, Zhen Cui

Subject: Chemistry And Materials Science, Applied Chemistry Keywords: PVC; thermal stabilizers; bi-functional; di-mannitol adipate ester-based zinc metal alkoxide; plasticizers

Online: 1 April 2019 (10:08:12 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202103.0328.v1

Epitope Mapping of the Diphtheria Toxin and Development of an ELISA-Specific Diagnostic Assay

Salvatore Giovanni De-Simone, Larissa Rodrigues Gomes, Paloma Napoleão-Pêgo, Guilherme Curty Lechuga, Jorge Soares de Pina, Flavio Rocha Silva

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Diphtheria toxin; B epitopes; epitope mapping; bi-specific peptides; ELISA; diagnostic performance

Online: 11 March 2021 (16:43:02 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202011.0310.v1

A Bi-Objective Home Health Care Routing and Scheduling Model with Considering Nurse Downgrading Costs

Pouria Khodabandeh, Vahid Kayvanfar, Majid Rafiee, Frank Werner

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Home health care; Routing and scheduling; Nurse downgrading; Epsilon-constraint method; Bi-objective optimization.

Online: 10 November 2020 (12:20:43 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201811.0133.v1

AC Dielectric Strength of Mineral Oil-Based Fe₃O₄ and Al₂O₃ Nanofluids

Usama Khaled, Abderrahmane Beroual

Subject: Engineering, Electrical And Electronic Engineering Keywords: AC dielectric strength; insulating oils; mineral oil-based nanofluids; statistical analysis; Weibull distribution; normal distribution

Online: 6 November 2018 (10:20:49 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202102.0130.v1

A Novel Treatment of the Josephson Effect

Jacob Szeftel, Nicolas Sandeau, Michel Abou Ganthous

Subject: Physical Sciences, Acoustics Keywords: Josephson effect; transport properties; critical current; tunnelling; superconducting-normal transition; negative resistance

Online: 4 February 2021 (10:01:16 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints201902.0238.v1

The Development of Silica Hydride Stationary Phases for High Performance Liquid Chromatography from Conception to Commercialization

Maria Matyska, Joseph Pesek

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: hydride surface; silicon-carbon bond; aqueous normal phase; retention mechanism

Online: 26 February 2019 (11:33:15 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202012.0504.v1

The Videofluorographic Swallowing Study: A Review of Literature

Umar Farooque, Syed Adeel Hassan, SM Ismail Shah, Saba Asif, Muhammad Humayoun Rashid, Abubakar Tauseef

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: dysphagia; swallowing impairment; videofluorographic swallowing study; literature review; procedures; indications; normal and critical findings; interfering factors; complications; clinical significance

Online: 21 December 2020 (10:55:05 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201807.0145.v2

Rényi Entropy Power Inequalities via Normal Transport and Rotation

Olivier Rioul

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: Rényi entropy; entropy power inequalities; transportation arguments; normal distributions; escort distributions; log-concave distributions

Online: 23 August 2018 (04:24:58 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202003.0157.v1

Stress Tensor and Gradient of Hydrostatic Pressure in the Contact Plane of Axisymmetric Bodies Under Normal and Tangential Loading

Emanuel Willert, Fabian Forsbach, Valentin L. Popov

Subject: Engineering, Mechanical Engineering Keywords: stress state; pressure gradient; normal contact; tangential contact; friction; axial symmetry; method of dimensionality reduction

Online: 10 March 2020 (03:22:49 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202102.0477.v1

Vertexes in Kinetic Space-Matter With Local Stresses Instead of Localized Particles With Distant Gravitation

Igor Bulyzhenkov

Subject: Physical Sciences, Acoustics Keywords: Pulsating self-organization; Metric monism; Geodesic cooling/warming; Continuous mass; Bi-vertex energy

Online: 22 February 2021 (14:29:41 CET)

Show abstract| Download PDF| Share

Due to the fact that negative energies have no existence in physical reality, the advanced mechanics of purely positive energies should describe gravitational interactions and collisions in monistic terms of extended kinetic energies and their local stresses. Such non-Newtonian mechanics of continuous inertial densities reinforces the Cartesian concept of matter-extension in the metric formalism of Einstein-Grossmann with a supplemental (dark, aether) fraction of bi-vertex mass-energy distributions. Local accelerations or decelerations of mono-vertex material densities in a multi-vertex distribution of complete kinetic energy arise under its constant integral due to nonlocal organization of continuous densities. Such integral conservation of the distributed mass-energy occurs instantaneously throughout the whole continuum of correlated densities and metric stresses despite the time-varying contributions of complementary mono-vertex and bi-vertex fractions. Under the nonlocal organization of purely kinetic (positive) mass-energy, geodesic self-heating and self-cooling of the pulsating space-matter conserve the integral energy in the two-fraction virial theorem for the averaged motion of visible mono-vertexes in the presence of invisible bi-vertex (interference, dark) mass-energy. Metric stresses of such material space are subordinate to nonlocal self-government of continuously distributed kinetic energy, including the relativistic rest-energy of General Relativity. These mutually consistent or correlated stresses in inertial space-time-energy create timelessly coordinated self-accelerations, observed for dense material volumes as distant gravitational pulls. In order to falsify/verify the nonlocal self-organization of adaptive kinetic energy, the monistic mechanics of self-consistent inertial densities and metric stresses can suggest moderate field changes in the temporal redshift, cycles of geodetic falls and takeoffs in pulsating kinetic organizations, and the calculated acceleration of the expanding Metagalaxy in its current phase of geodesic self-cooling.

Preprint ARTICLE | doi:10.20944/preprints202203.0065.v1

Dielectric Properties of Aqueous Solutions at Normal and High Dilutions

Sergey Vladimirovich Savel’ev, Ludmila Arkad’evna Morozova

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: radiothermal signals; radiobrightness temperature; normal and high dilution solutions; absorption coefficient; ion hydration shell; new dielectric properties; supramolecular interactions; dispersion

Online: 3 March 2022 (13:52:45 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201807.0397.v2

Genome-Wide Association Study and Selection Signatures Detect Genomic Regions Associated with Seed Yield and Oil Quality in Flax

Frank You, Jin Xiao, Pingchuan Li, ZHEN YAO, Gaofeng Jia, Liqiang He, Santosh Kumar, Braulio Soto-Cerda, Scott Duguid, Helen Booker, Khalid Rashid, Sylvie Cloutier

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: flax; genome-wide association study (GWAS); selective sweep; genotyping by sequencing (GBS); bi-parental population; single nucleotide polymorphism (SNP); seed yield; plant height; maturity; fatty acid composition

Online: 3 August 2018 (15:34:24 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202108.0272.v1

Remaining Useful Life Prediction from 3D Scan Data with Genetically Optimized Convolutional Neural Networks

Giovanni Diraco, Pietro Siciliano, Alessandro Leone

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: Remaining Useful Life; Deep Neural Network; Convolutional Neural Network; Genetic Optimization; Neural Network Optimization; Support Vector Regression; Depth Maps; Normal Maps; 3D Point Clouds.

Online: 12 August 2021 (10:40:23 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202002.0031.v1

Direct Electron Transfer-type Bioelectrocatalysis of Redox Enzymes at Nanostructured Electrodes

Taiki Adachi, Yuki Kitazumi, Osamu Shirai, Kenji Kano

Subject: Chemistry And Materials Science, Electrochemistry Keywords: direct-electron transfer-type bioelectrocatalysis; nanostructures; mesoporous electrodes, curvature effect; protein engineering; bi-directional bioelectrocatalysis; hydrogenase; fructose dehydrogenase; bilirubin oxidase; formate dehydrogenase; ferredoxin-NADP+ reductase

Online: 3 February 2020 (13:34:02 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202010.0014.v1

Enhancement Magneto-optic Properties of Radio-Frequency-Magnetron-sputtered Bi-containing Ferrite Garnet-Type Thin-films using Oxygen plasma treatment and metal-oxide protective layers

V. A. Kotov, Mohammad Nur-E Alam, Mikhail Vasiliev, D. E. Balabanov, V. I. Burkov, Kamal Alameh

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: Bi-substituted; magneto-optic; MCD; Faraday rotation; Figure of merit; imaging; sensing; polarization; Oxygen plasma treatment.

Online: 1 October 2020 (12:21:44 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202002.0368.v1

Evaluation of Combined Use of Drought Indices in the Case of Konya Closed Basin

Huseyin Yildirim Dalkilic

Subject: Engineering, Civil Engineering Keywords: Aridity Index (AI); Percentage of Normal Index (PNI); Standardized Precipitation -Evopotranspiration Index (SPEI); Standardized Precipitation Index (SPI); Drought; Factor Analysis; Reliability Analysis

Online: 25 February 2020 (11:09:28 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202104.0503.v1

Gröbner-Shirshov Bases Theory for Trialgebras

Juwei Huang, Yuqun Chen

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Gröbner-Shirshov basis; normal form; Gelfand-Kirillov dimension; trialgebra; trisemigroup

Online: 19 April 2021 (15:19:28 CEST)

Show abstract| Download PDF| Share

Working Paper ARTICLE

Recognition of Potential COVID-19 Drug Treatments Through the Study of Existing Protein-Drug and Protein-Protein Structures: An Analysis of Kinetically Active Residues

Ognjen Perišić

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: Covid-19; proteins; normal-modes; protein-drug interactions; chloroquine; ivermectin; remdesivir; sofosbuvir; boceprevir; α-difluoromethylornithine (DMFO)

Online: 11 August 2020 (04:09:43 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202112.0141.v1

Cross Entropy Covariance Matrix Adaptation Evolution Strategy Solving the Bi-Level Bidding Optimization Problem in Local Energy Markets with Renewables

Dharmesh Dabhi, Kartik Pandya, Joao Soares, Fernando Lezama, Zita Vale

Subject: Engineering, Electrical And Electronic Engineering Keywords: Bi-level Problem; Covariance Matrix; Cross-Entropy Method; Local Energy Market; Optimal Bidding

Online: 8 December 2021 (14:47:52 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202204.0290.v1

Multi-Indices Diagnosis of the Conditions That Have Led to the Two 2017 Major Wildfires in Portugal

Cristina Andrade, Lourdes Bugalho

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Fire Weather Index (FWI); Continuous Haines Index (CHI); Burning Index (BI); Keetch-Byram drought index (KBDI); Fire Danger index (FDI); Spread Component (SP); Wildfires; Portugal

Online: 29 April 2022 (08:02:54 CEST)

Show abstract| Download PDF| Share

Forest fires though part of a natural forest renewal process, when frequent and assuming large-scale proportions have detrimental impacts on biodiversity, agroforestry systems, soil erosion, air and water quality, infrastructures, and economy. Portugal (PT) endures extreme forest fires, with a record of burned area in 2017. These extreme wildfire events (EWE) concentrated in few days but with high burned areas, are among other factors, linked to severe fire weather conditions. In this study a comparison between several fire danger indices is performed for a reference period 2001‒2021 and 2017 (May‒October) for the Fire Weather Index (FWI), Continuous Haines Index (CHI), Keetch-Byram drought index (KBDI), Burning Index (BI) and Fire Danger index (FDI). A daily analysis for the so-called Pedrogão Grande wildfire (June 17th) and the October major fires (October 15th) included the Spread Component (SP) and Ignition Component (IC). Results revealed high above average values for all indices for 2017 in comparison with 2001‒2021 particularly, for October. High statistically significant monthly correlations between FWI, FDI and BI were found, along with lower between FWI and CHI. These correlations are depicted in the spatial patterns between FWI and FDI for the two EWE. The spatial distribution of FDI, SC and IC had the best performance in capturing the locations of the occurrence of the two EWEs’. The outcomes allowed to conclude, that since fire danger depends on several factors a multi-index’s diagnosis is highly relevant, though calibration and scale adjustment are needed for PT. The implementation of a Multi-index’s Prediction System should be able to further enhance the ability of tracking and forecast unique EWE, since the shortcomings of some indices are compensated by the information retrieved by others as shown in this study. Overall, a new forecast system can help ensuring the development of appropriate spatial preparedness plans, proactive responses by the civil protection regarding firefighter’s management, suppression efforts to minimize the detrimental impacts of wildfires in Portugal.

Preprint TECHNICAL NOTE | doi:10.20944/preprints202203.0166.v1

A Note on Novel Normal-Power Non-Linear Function

Matthew Iwada Ekum

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: Bimodal Dependent Variable; Normal-Power; Non-Linear; Least Square Estimation; Economy-Tourism Model

Online: 11 March 2022 (10:07:40 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202203.0309.v1

Update on Glycosphingolipids Abundance in Hepatocellular Carcinoma

Frances Byrne, Ellen Olzomer, Nina Lolies, Kyle Lee Hoehn, Marthe-Susanna Wegner

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: glycolysis; GEMs; oxidative phosphorylation; UGCG; glucosylceramide; normal liver cells; gangliosides; lacto/neo-lacto series GSLs; sulfatides

Online: 23 March 2022 (04:39:25 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201809.0559.v1

Normal Bases on Galois Ring Extensions

Zhang Aixian, Feng Keqin

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Galois ring; optimal normal basis; multiplicative complexity; finite field

Online: 28 September 2018 (09:41:32 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202111.0535.v1

On the ROC Area of Ensemble Forecasts for Rare Events

Zied Ben Bouallegue, David S. Richardson

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: ROC area; discrimination; verification artefacts; trapezoidal approximation; bi-normal model; imprecise probability

Online: 29 November 2021 (12:36:55 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202011.0234.v1

The Basin Stability of Bi-Stable Friction-Excited Oscillators

Merten Stender, Norbert Hoffmann, Antonio Papangelo

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: nonlinear dynamics; basin of attraction; self-excitation; bi-stability; multi-stability

Online: 6 November 2020 (09:21:32 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202007.0154.v1

Structural Changes in Boreal Forests Can Be Quantified Using Terrestrial Laser Scanning

Tuomas Yrttimaa, Ville Luoma, Ninni Saarinen, Ville Kankare, Samuli Junttila, Markus Holopainen, Juha Hyyppä, Mikko Vastaranta

Subject: Biology And Life Sciences, Forestry Keywords: spatiotemporal; time series; bi-temporal; ground-based LiDAR; tree growth

Online: 8 July 2020 (11:56:08 CEST)

Show abstract| Download PDF| Share

Terrestrial laser scanning (TLS) has been adopted as a feasible technique to digitize trees and forest stands, providing accurate information on tree and forest structural attributes. However, there is limited understanding on how a variety of forest structural changes can be quantified using TLS in boreal forest conditions. In this study, we assessed the accuracy and feasibility of TLS in quantifying changes in the structure of boreal forests. We collected TLS data and field reference from 37 sample plots in 2014 (T1) and 2019 (T2). Tree stems typically have planar, vertical, and cylindrical characteristics in a point cloud, and thus we applied surface normal filtering, point cloud clustering, and RANSAC-cylinder filtering to identify these geometries and to characterize trees and forest stands at both time points. The results strengthened the existing knowledge that TLS has the capacity to characterize trees and forest stands in space and showed that TLS could characterize structural changes in time in boreal forest conditions. Root-mean-square-errors (RMSEs) in the estimates for changes in the tree attributes were 0.99-1.22 cm for diameter at breast height (Δdbh), 44.14-55.49 cm2 for basal area (Δg), and 1.91-4.85 m for tree height (Δh). In general, tree attributes were estimated more accurately for Scots pine trees, followed by Norway spruce and broadleaved trees. At the forest stand level, an RMSE of 0.60-1.13 cm was recorded for changes in basal area-weighted mean diameter (ΔDg), 0.81-2.26 m for changes in basal area-weighted mean height (ΔHg), 1.40-2.34 m2/ha for changes in mean basal area (ΔG), and 74-193 n/ha for changes in the number of trees per hectare (ΔTPH). The plot-level accuracy was higher in Scots pine-dominated sample plots than in Norway spruce-dominated and mixed-species sample plots. TLS-derived tree and forest structural attributes at time points T1 and T2 differed significantly from each other (p < 0.05). If there was an increase or decrease in dbh, g, h, height of the crown base, crown ratio, Dg, Hg, or G recorded in the field, a similar outcome was achieved by using TLS. Our results provided new information on the feasibility of TLS for the purposes of forest ecosystem growth monitoring.

Preprint ARTICLE | doi:10.20944/preprints202207.0098.v1

Analysis of Confirmatory Auditory Responses in Unilateral Tinnitus Patients with Normal Hearing

Yong Jun Jeong, Kyoung Ho Oh, Sung Jin Lim, Dong Heun Park, Yoon Chan Rah, June Choi

Subject: Medicine And Pharmacology, Otolaryngology Keywords: tinnitus; normal hearing; Evoked potentials; auditory; brain stem; otoacoustic emission

Online: 6 July 2022 (13:54:44 CEST)

Show abstract| Download PDF| Supplementary Files| Share

In patients with unilateral tinnitus with normal hearing, several studies have compared the ipsilateral and contralateral ears; however, few studies have investigated its relationship with the duration of tinnitus. We compared the auditory brainstem response and otoacoustic emission parameters between ipsilateral and contralateral ears in adults with unilateral tinnitus and normal hearing. This retrospective review included 84 patients with unilateral tinnitus and normal hearing who underwent auditory brainstem response and otoacoustic emission; they were categorized according to the duration of tinnitus. The latencies and amplitudes of waves I, III, and V, and V/I ratio of both ears in auditory brainstem response, and the results of distortion-product otoacoustic emission and transient evoked otoacoustic emission were examined. The auditory brainstem response parameters, distortion-product otoacoustic emission parameters, and transient evoked otoacoustic emission parameters between the ipsilateral and contralateral ears along the duration of tinnitus were analyzed. Moreover, the failure rates of both distortion-product otoacoustic emission and transient evoked otoacoustic emission between the ears along with the duration and the effects of the variables on the amplitude and latency of each wave were examined. Although there was little significant difference between the ipsilateral and contralateral ears, laterality seemed to have an effect on wave I latency in the multiple linear regression analysis. The distortion-product otoacoustic emission failure rate of the ipsilateral ear was higher than that of the contralateral ear in all patients. However, there was no remarkable difference between the ears in the distortion-product otoacoustic emission and transient evoked otoacoustic emission parameters throughout the duration. We found that outer hair cells and the distal portion of the cochlear nerve are possible pathologic lesions in tinnitus with normal hearing and cochlear synaptopathy could be suspected. Further studies, including those on inner hair cells and higher central cortex, are needed.

Preprint ARTICLE | doi:10.20944/preprints202111.0074.v1

Isochoric Specific Heat in the Dual Model of Liquids

Fabio Peluso

Subject: Physical Sciences, Condensed Matter Physics Keywords: Liquid model; Phonons in liquids; Instantaneous Normal Modes; Mesoscopic model of liquids; Phonon – particle interaction; Specific heat

Online: 3 November 2021 (09:14:38 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202007.0307.v1

Edge-based Color Image Segmentation using Particle Motion on Vector Fields Derived from Local Color Distance Images

Wutthichai Phornphatcharaphong, Nawapak Eua-Anant

Subject: Computer Science And Mathematics, Computer Science Keywords: Color images segmentation; Particle Motion; Local Color Distance Images; Normal compressive vector field; Edge vector field

Online: 14 July 2020 (12:09:23 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202111.0274.v1

Rayleigh–Bénard Instability of an Ellis Fluid Saturated Porous Channel with an Isoflux Boundary

Pedro Vayssière Brandão, Michele Celli, Antonio Barletta

Subject: Engineering, Mechanical Engineering Keywords: Ellis fluid; Porous medium; Normal modes; Rayleigh–Bénard instability; Convection.

Online: 15 November 2021 (19:39:24 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202010.0405.v1

Electroreduction of Bi(III) Ions in the Aspect of Expanding the ”Cap – Pair” Effect

Agnieszka Nosal Wiercińska, Sławomira Skrzypek

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: cap - pair effect; electrochemistry; electroreduction of Bi(III); active complexes; catalytic activity

Online: 20 October 2020 (08:36:05 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202303.0112.v1

Brief History of Thermodynamic Research on Microorganisms

Marko Popovic

Subject: Biology And Life Sciences, Virology Keywords: Viruses; Escherichia coli; Klebsiella aerogenes; Candida utilis; Gibbs energy of biosynthesis; Bi-osynthesis reaction; Enthalpy; Entropy; Pathogen-host interaction

Online: 6 March 2023 (15:47:22 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.1002.v1

New Subfamily of Bi-starlike and Bi-convex Functions Defined by the q-Janowski Function

Abdullah Alsoboh, Ala Amourah, Fethiye Müge Sakar, Daniel Breaz

Subject: Computer Science And Mathematics, Mathematics Keywords: Analytic functions; univalent and bi-univalent functions; Subordination; q-Janowski 5 Function; Fekete-Szegö problem; Quantum calculus.

Online: 14 June 2023 (07:25:18 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202304.1182.v1

Implementation of Deep Learning based Bi-Directional DC-DC Converter for V2V and V2G applications in Microgrid - An Experimental Investigation

Sreedhar Madichetty, Mohan Krishna Banda, Shanthi Kumar Nandavaram Banda

Subject: Engineering, Electrical And Electronic Engineering Keywords: Non-isolated bi-directional converter (NIBC) 2; V2V charger 3; Deep learning 4; High voltage 5; Low voltage

Online: 28 April 2023 (12:54:21 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202211.0251.v1

The impact of BMI on Ovarian Cancer- An Updated Systematic Review and Metanalysis

Nikolaos Tzenios, Mary Tazanios, Mohamed Chahine

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: ovarian cancer; BMI; obesity; overweight; normal weight; statistical significance

Online: 14 November 2022 (09:57:58 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202308.1678.v1

FLASH Radiation Therapy- Key Physical Irradiation Parameters and Beam Characteristics

roya boodaghi malidarre, Hesham M.H. Zakaly

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: CONV-RT; FLASH-RT; ultra-high-dose-rate; beam characteristics; pulsed beams; normal tissue sparing

Online: 24 August 2023 (04:10:58 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202302.0173.v1

Proposing Intranasal Rifampin for Alzheimer’s Disease and the Other Age-Related Neurodegenerative Proteinopathies

Coad Thomas Dow, Laith Kidess

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: ifampin; proteinopathies; permeability glycoprotein; intranasal; bi-directional; Alzheimer’s; Parkinson’s; Lewy body dementia; multiple system atrophy; huntington’s; amyotrophic lateral sclerosis/frontotemporal dementia spectrum

Online: 10 February 2023 (02:31:56 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202210.0396.v1

Feasibility Study of Cable Routing for Bi-Planar Trajectory Tracking in Cable Driven Lower Limb Exoskeleton

Rajan Prasad, Marwan El-Rich, Mohammad I. Awad, Sunil K. Agrawal, Kinda Khalaf

Subject: Engineering, Mechanical Engineering Keywords: cable driven; exoskeleton; lower limb rehabilitation; hip adduction; bi-planar trajectory; optimized routing.

Online: 26 October 2022 (03:54:13 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202311.0244.v1

Delving into the Digital Twin Developments and Applications Beyond BIM in the Construction Industry

Muhammad Afzal, Rita Yi Man Li, Muhammad Shoaib, Muhammad Faisal Ayyub, Lavinia Chiara Tagliabue, Muhammad Bilal, Habiba Ghafoor

Subject: Engineering, Architecture, Building And Construction Keywords: Bi-directional Interoperability; Building Information Modelling (BIM); Construction 4.0; Digital Transformation; Digital Twin (DT); DT Advancements; DT Technologies; Holistic Review

Online: 3 November 2023 (11:04:37 CET)

Show abstract| Download PDF| Share

Construction 4.0 is witnessing exponential growth in Digital Twin (DT) technology developments and applications, revolutionizing the adoption of Building Information Modelling (BIM) and other emerging technologies used throughout the lifecycle of the built environment. BIM provides technologies, procedures, and data schemas representing building components and systems. At the same time, DT enhances this with real-time data for cyber-physical integration, enabling live asset monitoring and better decision-making. Despite being in the early stages of development, DT applications have rapidly progressed in the AEC sector, resulting in a diverse literature landscape due to the various technologies and parameters involved in fully developing the DT technology. The intricate complexities inherent in digital twin advancements have confused professionals and researchers. This confusion arises from the nuanced distinctions between the two technologies, i.e., BIM and DT, causing a convergence that hinders realizing their potential. To address this confusion and lead to a swift development of DT technology, this study presents a holistic review of the existing research focusing on the critical components responsible for developing DT applications in the construction industry. The study identifies five crucial elements: technologies, maturity levels, data layers, enablers, and functionalities. Additionally, it identifies research gaps and proposes future avenues for streamlined DT developments and applications in the AEC sector. Future researchers and practitioners can target data integrity, integration and transmission, bi-directional interoperability, nontechnical factors, and data security to achieve mature digital twin applications for AEC practices. This study highlights the growing significance of DTs in construction and provides a foundation for further advancements in this field to harness its potential to transform built environment practices.

Preprint ARTICLE | doi:10.20944/preprints202403.0858.v1

Experimental Study of White Light Interferometry in Mach-Zehnder Interferometers Based on Standard Single Mode Fiber

J. L. Cano-Perez, J. Gutierrez-Gutiérrez, C. Perezcampos-Mayoral, E. Perez-Campos, M. S. Pina-Canseco, L. Tepech-Carrillo, M. Vargas-Treviño, E. I. Guerra-Hernandez, A. Martinez-Helmes, J. M. Estudillo-Ayala, J. M. Sierra-Hernandez, R. Rojas-Laguna

Subject: Physical Sciences, Optics And Photonics Keywords: White light interference, bi-tapers and core-offset Mach-Zehnder interferometer.

Online: 14 March 2024 (13:00:18 CET)

Show abstract| Download PDF| Share

Working Paper ARTICLE

On the Optimization of the Bus Network Design: An Analytical Approach Based on a Bi-modal Macroscopic Fundamental Diagram

Igor Dakic, Ludovic Leclercq, Monica Menendez

Subject: Social Sciences, Transportation Keywords: Bus network design; Trip length distribution; Bi-modal MFD; Space allocation; Bus operations

Online: 26 June 2020 (12:26:27 CEST)

Show abstract| Download PDF| Share

Public transport systems are considered to be a crucial aspect of a sustainable urban development, as they allow more passengers to efficiently travel across an urban area at low environmental and economic costs. Multiple factors can influence the public transport level of service. All take roots in the network structure and the operating regime, i.e. how bus lines are arranged atop the street network and how the service frequency is adjusted to meet urban mobility patterns. This is known as the bus network design problem and has been the subject of several studies. The problem is so challenging that most studies until now resort to strong assumptions such as a static description of the peak hour demand, homogeneous user behavior, and equal trip lengths. Potential effects of different types of user behavior and trip lengths patterns on the user and/or operator cost function have not been investigated whatsoever. Moreover, the existing studies have not considered the effects of the bus network structure on private car users, the level of interactions between the two modes, and the passenger mode choice that depends on the traffic conditions. This paper aims to close this gap and provide a general framework considering multiple trip length patterns, two types of user behavior, and the effects that the bus network structure might have on the traffic performance and passenger mode choice. For modeling different trip length patterns, the proposed approach combines all origin-destination pairs with the same trip length and uses the trip length distribution as an intermediate level of abstraction. As such, it allows to solve the optimal bus network design problem in an analytical way, while considering a more realistic setting including network congestion, mixed traffic, and different mode choice decisions depending on trip lengths and walking preferences. Numerical analysis reveals that both, the user behavior and the trip length patterns, have significant effects on the operator and user cost function. Results show that the probability of choosing any given mode is not constant across the user trip lengths, but follows certain distribution. This distribution is not unique, but varies across the trip length patterns, indicating the importance of modeling the mode choice at the trip length level. Finally, the analysis demonstrates the significance of addressing simplifications made in previous studies.

Preprint ARTICLE | doi:10.20944/preprints202311.0496.v1

Marina Khodanovich, Mikhail Svetlik, Anna Naumova, Daria Kamaeva, Anna Usova, Marina Kudabaeva, Tatyana Anan’ina, Irina Wasserlauf, Valentina Pashkevich, Marina Moshkina, Victoria Obukhovskaya, Nadezhda Kataeva, Anastasia Levina, Yana Tumentceva, Vasily Yarnykh

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: normal aging; myelin; quantitative MRI; neuroimaging; macromolecular fraction mapping; magnetization transfer; MPF; white matter; FLAIR hyperintensities; demyelination; myelin-specific autoantibodies; myelin basic protein, proteolipid protein

Online: 8 November 2023 (07:41:37 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202305.2115.v1

Initial Coefficients Bounds for Bi-univalent Functions Related to Gregory Coefficients

Gangadharan Murugusundaramoorthy, Kaliappan Vijaya, Teodor Bulboaca

Subject: Computer Science And Mathematics, Analysis Keywords: univalent functions; bi-univalent functions; starlike and convex functions of some order; subordination; Fekete-Szeg\H{o} problem

Online: 30 May 2023 (10:38:03 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202304.0292.v1

Blood Pressure Correlates with Serum Leptin and Body Mass index in Overweight Male Saudi Students

Shalan Alaamri, Abdulhalim S. Serafi, Zahir Hussain, Munira M. Alrooqi, Mohammed A. Bafail, Sumera Sohail

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: systolic blood pressure; diastolic blood pressure; serum leptin; body mass index; normal and overweight male students

Online: 13 April 2023 (03:41:43 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202310.1091.v1

All Bi-Unitary Superperfect Polynomials over F2 with at Most Two Irreducible Factors

Haissam Chehade, Domoo Miari, Yousuf Alkhezi

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: sum of divisors; bi-unitary divisors; polynomials; finite fields; characteristic 2

Online: 17 October 2023 (11:59:49 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202308.0828.v1

Scipion-EM-ProDy: A Graphical Interface for the ProDy Python Package within the Scipion Workflow Engine enabling Integration of Databases, Simulations and Cryo-Electron Microscopy Image Processing

James Michael Krieger, Carlos Oscar S. Sorzano, Jose Maria Carazo

Subject: Biology And Life Sciences, Biophysics Keywords: global protein dynamics; software integration workflows; cryo-electron microscopy; normal mode analysis; elastic network models; ensemble analysis; principal component analysis; hybrid simulations

Online: 10 August 2023 (10:52:04 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.1763.v1

Molecular DNA Barcoding and Fertilization Effects on Growth and Herbal Quality Features of Cultivated Sideritis syriaca subsp. syriaca, a Local Endemic Plant of Crete with High Medicinal Value

Konstantinos A Paschalidis, Dimitrios Fanourakis, Georgios Tsaniklidis, Ioannis Tsichlas, Vasileios A. Tzanakakis, Fotis Bilias, Eftichia Samara, Ioannis Ipsilantis, Katerina Grigoriadou, Ioulietta Samartza, Theodora Matsi, Georges Tsoktouridis, Nikos Krigas

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Molecular markers, genetic characterization, antioxidant, carotenoids, flavonoids, Greece, phenols, bi-ostimulant; malotira; Mountain tea

Online: 22 December 2023 (17:07:02 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202305.1549.v1

The Heterogeneous Progressive Multiple Sclerosis Lesion. How Can We Assess and Modify a Degenerating Lesion?

Olivia Ellen, Sining Ye, Danica Nheu, Mary Dass, Maurice Pagnin, Ezgi Ozturk, Paschalis Theotokis, Nikolaos Grigoriadis, Steven Petratos

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: multiple sclerosis; oligodendrocyte; myelination; inflammation; microglia; macrophage; bi-omarkers; imaging diagnostics

Online: 23 May 2023 (03:39:19 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202212.0452.v1

Idiopathic Normal Pressure Hydrocephalus Diagnosis: Quantitative and Qualitative Score Predicting Outcome of Extended Lumbar Drainage

Maria Caffo, Roberta Laera, Maria Luisa Gorgoglione, Antonello Curcio, Giuseppina Marzano, Gerardo Caruso, Antonino Germanò

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Extended lumbar drainage; Hydrocephalus; Idiopathic normal pressure hydrocephalus; neurodegenerative diseases; Qualitative neurocognitive tests; Quantitative neurocognitive tests

Online: 23 December 2022 (08:09:41 CET)

Show abstract| Download PDF| Share

Background: Idiopathic normal pressure hydrocephalus is a syndrome with neuroradiological findings and clinical pattern characteristic but not specific for the pathology. Since the prevalence is growing due to the rapidly aging society, standardized and validated protocol for diagnosis is needed, also because this condition may mimic other disorders among elderly such as Parkinson's and Alzheimer's disease. Material and methods: We analysed data from 44 patients with suspect diagnosis of idiopathic normal pressure hydrocephalus with age > 60 years, clinical triad and neuroradiological pattern examined in our ward from November 2018 to November 2022. Neu-ropsychological assessment includes Mini Mental State Examination and Mental Deterioration Battery. Motor scores were collected from gait and balance tests. The evaluation was performed before and after an extended lumbar drainage last 48h. Patients who has scores improvement after the extended lumbar drainage, undergo ventriculoperitoneal shunt with a programmable valve. Results: All patients undergo neuropsychological assessment and motor tests, only 2 patients were unable to perform motor tests because bedridden. 16 patients showed no benefit from the tests, in 2 cases even a worsening of cognitive performance. 28 patients showed an improvement in their performances, but in most cases the improvement involved only the neuropsychological as-sessment. All patients underwent ventriculoperitoneal shunt have had a typical answers pattern in Mental Deterioration Battery test. We performed 9 ventriculoperitoneal shunt and 1 ventricu-lo-atrial shunt. Conclusions: Qualitative neurocognitive tests come out to be more sensitive compared to quantitative neurocognitive tests in identifying patients with suspected idiopathic normal pressure hydrocephalus benefiting from extended lumbar drainage test and then un-derwent surgical treatment. This could be considered a valid screening in elderly patients with suspected idiopathic normal pressure hydrocephalus in order to minimize the number of invasive procedures. More studies are necessary to validate this tool.

Preprint ARTICLE | doi:10.20944/preprints202309.0769.v1

Asymmetric Probabilistic Tsetlin Machine for Pattern Recognition

Negar Elmisadr, Mohamed Bachir Belaid, Anis Yazidi

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Asymmetric Probabilistic Tsetlin(APT) Machine; Tsetlin Automata(TA); stochastic point location (SPL); Asymmetric steps; random search; decaying normal distribution; state transition probability

Online: 12 September 2023 (11:30:00 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.0255.v1

Innovation and Sustainability in Business Turbulence: Navigating the ‘Now Normal’ through Value Co-creation

Ayantunji Gbadamosi, Nnamdi O Madichie, Emmanuel Mogaji

Subject: Business, Economics And Management, Marketing Keywords: COVID-19; Entrepreneurship; SMEs; Opportunity-necessity nexus; Value co-craetion; Now-normal; Sustainability; Turbulence; Innovation

Online: 3 November 2023 (14:34:23 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202304.0982.v1

Molecular Mechanisms Driven by MT4-MMP in Cancer Progression

Emma Muñoz-Sáez, Natalia Moracho, Ana I. R. Learte, Alice Collingnon, Alicia G. Arroyo, Agnés Noel, Nor Eddine Sounni, Cristina Sánchez-Camacho

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: MT4-MMP; MMP-17; development; vasculature; tumor; cancer cell; malignancy; therapy; bi-omarker

Online: 26 April 2023 (11:19:22 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202209.0252.v1

Fundamentally Good Alternative to Normal Distribution

Kabir Bindawa Abdullahi

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: alternative parameterization; normal distribution; dispersion estimators; location-invariance; scale-invariance; scale-and-location-invariance

Online: 19 September 2022 (02:06:09 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.0822.v1

Time-Course Morphological Analysis Using Normal and Local Curvature Information from 3D Modelling Data for Leaf Lettuce

Kaede C. Wada, Atsushi Hayashi, Unseok Lee, Takanari Tanabata, Sachiko Isobe, Hironori Itoh, Hideki Maeda, Satoshi Fujisako, Nobuo Kochi

Subject: Computer Science And Mathematics, Analysis Keywords: 3D; point cloud; measurement; visual assessment; normal vector; local curvature; compactness; phenotyping; leaf lettuce (Lactuca sativa); blistering

Online: 12 June 2023 (10:19:38 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.0069.v1

Unexpected Differences in the Speed of Non-malignant versus Malignant Cell Migration Reveal Differential Basal ATP Levels

Bareun Kim, Anthony T. Lopez, Indhujah Thevarajan, Maria F. Osuna, Monica Mallavarapu, Boning Gao, Jihan K. Osborne

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Cell Migration; Cancer cell migration; normal epithelial cell motility

Online: 1 November 2023 (11:18:02 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202307.1204.v1

Deep-ABSA: A Multichannel Deep Learning Framework For Aspect-Based Bangla Sentiment Analysis

Md Morshedul Islam, G.M. SAKHAWAT HOSSAIN, Dhiman Sarma, Rishita Chakma, Md Mynoddin

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: ABSA; word embedding; Bi-LSTM; attention; character embedding

Online: 18 July 2023 (09:47:17 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202310.1436.v1

Difference between WMO Climate Normal and Climatology: Insights from a Satellite-Based Global Cloud and Radiation Climate Data Record

Abhay Devasthale, Karl-Göran Karlsson, Sandra Andersson, Erik Engström

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: climate normal; climatology; satellite remote sensing; clouds and radiation; climate change; climate data records; climate monitoring; essential climate variables; climate anomalies; WMO

Online: 23 October 2023 (11:06:23 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0532.v1

Ferromagnetic Fluctuations in the Heavily Overdoped Regime of Single-Layer High-TC Cuprate Superconductors

Tadashi Adachi, Koshi Kurashima, Takayuki Kawamata, Takashi Noji, Satoru Nakajima, Yoji Koike

Subject: Physical Sciences, Condensed Matter Physics Keywords: ferromagnetic fluctuation; Tl-2201 cuprate; La-214 cuprate; Bi-2201 cuprate; electrical resistivity; magnetization

Online: 10 July 2023 (04:10:37 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.1943.v1

Determination of Active Pharmaceutical Ingredients in Saridon Tablets Using an Economical and Sensitive TLC Method Combined with Densitometry

Alina Pyka-Pająk

Subject: Medicine And Pharmacology, Pharmacy Keywords: APIs; Saridon; normal phase thin layer chromatography; densitometry

Online: 30 November 2023 (04:08:14 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202402.0916.v1

Floating Zone Growth of Pure and Pb-Doped Bi-2201 Crystals

Maria Roslova, Bernd Büchner, Andrey Maljuk

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Bi-2201; floating zone crystal growth; crystal structure; cuprates; superconductivity

Online: 17 February 2024 (09:10:37 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202305.1670.v1

Effect of Diffusion and Laser Pulse on a Poro-Thermoelastic Medium via Three-Phase-Lag Model

Mohamed Abdelsabour Fahmy, Mohamed I. A. Othman, Elsayed M. Abd-Elaziz

Subject: Engineering, Mechanical Engineering Keywords: Three-phase-lag model; Laser pulse; Diffusion; Voids; Normal mode analysis

Online: 24 May 2023 (02:39:07 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202308.1456.v1

Weighted Vest Intervention during Whole-Body Circuit Training Improves Plasma Resistin, Cardiovascular Disease Risk Factors, and Cardiorespiratory Fitness in Normal-Weight Obese Women

Ji Woong Kim, Eun Sook Kim, Do Hyun Kim, Sung Jin Yoon

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: circuit training; resistin; weighted vest; normal weight obesity; cardiopulmonary fitness; Vo2max; IL-6; hs-CRP, cardiovascular; cardiovascular disease risk factors

Online: 22 August 2023 (02:58:37 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202308.1268.v1

Simulation of Regular Operating Modes of Oil and Oil Product Pipelines

Mikhail Grigor'evich Sukharev

Subject: Engineering, Control And Systems Engineering Keywords: oil and oil-products pipelines; normal operation modes; Kirchhoff's laws; non- isothermal flows; stochastic model; maximum likelihood method; theory of hydraulic circuits.

Online: 17 August 2023 (08:05:57 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202401.1160.v1

Value-at-Risk Effectiveness: A High-Frequency Data Approach with Semi-heavy Tails

Mario Ivan Contreras-Valdez, Sonal Sahu, José Antonio Núñez-Mora, Roberto Joaquín Santillán-Salgado

Subject: Business, Economics And Management, Other Keywords: VaR; High-frequency data; Normal Inverse Gaussian distribution; Bitcoin; Ethereum

Online: 16 January 2024 (09:56:20 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.1990.v1

Properties of Narrative Productivity, Syntactic Complexity and Lexical Diversity of Typical Bi-dialectal Cypriot-Greek-Speaking Children

Theodora Papastefanou, Eleni Theodorou

Subject: Social Sciences, Language And Linguistics Keywords: retelling; microstructure analysis; Cypriot-Greek bi-dialectal children; typical language development

Online: 28 July 2023 (12:30:54 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202305.0562.v1

Intra-Articular Facet Joint Injection of Normal Saline for Chronic Low Back Pain: A Systematic Review and Meta-Analysis

Areerat Suputtitada, Tanawin Nopsopon, Thanitsara Rittiphairoj, KRIT Pongpirul

Subject: Medicine And Pharmacology, Anesthesiology And Pain Medicine Keywords: Facet joint injection; Chronic low back pain; Normal saline; Meta-analysis; Patient Reported Clinical Outcomes

Online: 9 May 2023 (04:22:14 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0187.v1

VaR Estimation Using Extreme Value Mixture Models for Cryptocurrencies

Stephanie Danielle Subramoney, Knowledge Chinhamu, Retius Chifurira

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: Bitcoin; cryptocurreny; extreme value models (EVM); GPD-Normal-GPD (GNG); generalised Pareto distribution (GPD); Kernel density estimator (KDE); Normal distribution; Value-at-Risk (VaR)

Online: 4 July 2023 (11:29:36 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202308.1928.v1

Using the BWA (Bertaut-Warren-Averbach) Method to Optimize the Technology of Crystalline Powders such as LiFePO4

Aleksandr Bobyl, Oleg Konkov, Mislimat Faradzheva, Igor Kasatkin

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: crystallites in powders; Lamé's shape; X-ray sizes; Bertaut-Warren-Averbach; Normal distributions; Lognormal distribution; energy storage; energy optimization

Online: 29 August 2023 (08:46:51 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202311.1517.v1

Benign Recurrent Intrahepatic Cholestasis: Where are we now?

Eleni V Geladari, Natalia G Vallianou, Evangelia Margellou, Dimitris Kounatidis, Vassilios Sevastianos, Alexandra Alexopoulou

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: Benign recurrent intrahepatic cholestasis; mutations; elevated conjugated bilirubin; normal gamma-glutamyl transferase

Online: 23 November 2023 (11:12:32 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202309.0364.v1

Cytokine Levels in Saliva Are Associated with Salivary Gland Fibrosis and Hyposalivation in Mice after Fractionated Radiotherapy of the Head and Neck

Olga Zlygosteva, Inga Solgård Juvkam, Hans Christian Dalsbotten Aass, Hilde Kanli Galtung, Tine Merete Søland, Eirik Malinen, Nina F. J. Edin

Subject: Biology And Life Sciences, Life Sciences Keywords: cytokines; X-rays; fractionated radiotherapy; normal tissue response; head and neck; salivary glands; fibrosis; mice

Online: 6 September 2023 (09:33:02 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202402.0770.v1

Ovarian Morphology in Non-hirsute, Normo-Androgenic, Eumenorrheic Premenopausal Women From a Multi-ethnic Unselected Siberian Population

Ludmila Lazareva, Larisa Suturina, Alina Atalyan, Irina Danusevich, Iana Nadeliaeva, Lilia Belenkaya, Irina Egorova, Kseniia Ievleva, Natalia Babaeva, Daria Lizneva, Richard S. Legro, Ricardo Azziz

Subject: Medicine And Pharmacology, Reproductive Medicine Keywords: pelvic ultrasound; follicle number per ovary; FNPO; ovarian volume; PCOM; upper normal limits; referral population

Online: 14 February 2024 (05:32:02 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202310.1281.v1

Effects of ESC/ESH-Based Written Lifestyle Advice including a Nutraceutical on 24-Hour Blood Pressure in High-Normal Blood Pressure Patients with Low Cardiovascular Risk

Matteo Landolfo, Francesco Spannella, Chiara Poliseno, Adriano Massacesi, Federico Giulietti, Roberto Festa, Enrico Cavazzin, Giulio Sasso, Alberto Mazza, Riccardo Sarzani

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: high-normal BP; hypertension; lifestyle; nutraceuticals; nitrates; beetroot

Online: 20 October 2023 (08:07:43 CEST)

Show abstract| Download PDF| Supplementary Files| Share

(1) Background: Lifestyle changes, eventually associated with a nutraceutical, are recommended strategies for managing high-normal blood pressure (BP) patients with low-moderate cardiovascu-lar (CV) risk. Nitrates-enriched products (i.e., red beet extracts) may help reduce BP, exerting vas-oactive properties and enhancing adherence to lifestyle advice. Our study aimed to evaluate the effectiveness in clinical practice of generic written lifestyle advice and a beetroot-based nutraceu-tical prescription based on the 2018 ESC/ESH guidelines on 24-hour BP in a population with high-normal BP and low-moderate CV risk.; (2) Methods: A longitudinal observational study was con-ducted in two ESH hypertension excellence centres on 43 consecutive subjects with high-normal BP based on repeated office BP (OBP) measurements and a low-moderate CV risk. Twenty-four-hour ambulatory BP monitoring (ABPM) was carried out at baseline and three months after ge-neric written ESC/ESH advice for lifestyle changes associated with a nutraceutical containing 500 mg of dry beetroot extract; (3) Results: Mean age 50±11 years, 54% males, 58% overweight/obese, mean OBP 135±3/85±3 mmHg. At baseline, 24-hour BP, daytime BP and night-time BP were 127±7/80±6 mmHg, 131±8/83±6 mmHg and 118±8/70±5 mmHg, respectively, BP profiles compat-ible with hypertension status in some subjects. After a median follow-up of 98 (92-121) days, all BPs, except night-time diastolic BP, were significantly decreased: -3±6/-2±4 mmHg for 24-hour BP, -3.9±6.0/-3.0±4.0 mmHg for daytime BP and -3.3±7.4/-1.3±4.7 mmHg for night-time BP, respec-tively. No significant clinical changes in weight were detected. BP decreased independently of baseline BP level, gender, smoking status and BMI, while a more substantial decrease in BP was observed in older patients; (4) Conclusions: Our pilot study shows for the first time that written generic lifestyle advice based on ESC/ESH hypertension guidelines coupled with a beetroot-based nutraceutical may represent a valid initial non-pharmacological approach in subjects with high-normal BP and low-moderate CV risk even without personalized diet interventions.

Preprint ARTICLE | doi:10.20944/preprints202305.1144.v1

Collagen Hydrolysate Effects on Photodynamic Efficiency of Gallium(III) Phthalocyanine on Pigmented Melanoma Cells

Vanya Mantareva, Ivan Iliev, Inna Sulikovska, Mahmut Durmus, Tsanislava Genova

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: bovine collagen hydrolysate; gallium phthalocyanine; pigmented melanoma; normal keratocytes and fibroblasts; mouse embryonal fibroblasts; photodynamic therapy

Online: 16 May 2023 (09:46:10 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202212.0474.v1

Delicate Comparison of the Central and Non-central Lyapunov Ratios with Applications to the Berry–Esseen Inequality for Compound Poisson Distributions

Vladimir Makarenko, Irina Shevtsova

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: Lyapunov fraction; extreme problem, moment inequality; central limit theorem; Berry–Esseen inequality; compound Poisson distribution; normal approximation

Online: 26 December 2022 (06:43:46 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202209.0162.v1

Bi-substituted Ferrite Garnet Type Magneto-Optic Materials Studied at ESRI Nano-Fabrication Laboratories, ECU, Australia

Mohammad Nur-E-Alam, Mikhail Vasiliev, Kamal Alameh

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: Bi-substituted; RF magnetron; Sputtering; Annealing; Oxygen plasma treatment; Magneto-optic; Faraday rotation; Figure of merit; Hysteresis loop; Imaging; Sensing.

Online: 13 September 2022 (05:53:32 CEST)

Show abstract| Download PDF| Share

Search Results

129 articles found