Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Brief History of Thermodynamic Research on Microorganisms

Version 1 : Received: 3 March 2023 / Approved: 6 March 2023 / Online: 6 March 2023 (15:47:22 CET)

How to cite: Popovic, M. Brief History of Thermodynamic Research on Microorganisms. Preprints 2023, 2023030112. https://doi.org/10.20944/preprints202303.0112.v1 Popovic, M. Brief History of Thermodynamic Research on Microorganisms. Preprints 2023, 2023030112. https://doi.org/10.20944/preprints202303.0112.v1

Abstract

Pathogen-host interaction (virus-host, bacteria-host and fungi-host) is analyzed from the perspective of biothermodynamics. A mechanistic model of pathogen-host interactions, which was earlier applied to virus-host interactions, was applied for the first time to bacteria-host and fungi-host interactions. Through a mechanistic model suggested in this research, it is possible to explain the phenomenon of tropism of microorganisms to develop infections in certain tissues. Gibbs energy of biosynthesis represents the driving force for growth of bacteria inside host organisms. A growing bacterial colony represents a thermodynamic system, while the host organism is its surroundings. The permissiveness coefficient determines the possibility of growth of bacteria in an appropriate environment (tissue).

Keywords

Viruses; Escherichia coli; Klebsiella aerogenes; Candida utilis; Gibbs energy of biosynthesis; Bi-osynthesis reaction; Enthalpy; Entropy; Pathogen-host interaction

Subject

Biology and Life Sciences, Virology

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.