Review Version 1 Preserved in Portico This version is not peer-reviewed
Brief History of Thermodynamic Research on Microorganisms
Version 1 : Received: 3 March 2023 / Approved: 6 March 2023 / Online: 6 March 2023 (15:47:22 CET)
How to cite: Popovic, M. Brief History of Thermodynamic Research on Microorganisms. Preprints 2023, 2023030112. https://doi.org/10.20944/preprints202303.0112.v1. Popovic, M. Brief History of Thermodynamic Research on Microorganisms. Preprints 2023, 2023030112. https://doi.org/10.20944/preprints202303.0112.v1.
Pathogen-host interaction (virus-host, bacteria-host and fungi-host) is analyzed from the perspective of biothermodynamics. A mechanistic model of pathogen-host interactions, which was earlier applied to virus-host interactions, was applied for the first time to bacteria-host and fungi-host interactions. Through a mechanistic model suggested in this research, it is possible to explain the phenomenon of tropism of microorganisms to develop infections in certain tissues. Gibbs energy of biosynthesis represents the driving force for growth of bacteria inside host organisms. A growing bacterial colony represents a thermodynamic system, while the host organism is its surroundings. The permissiveness coefficient determines the possibility of growth of bacteria in an appropriate environment (tissue).
Viruses; Escherichia coli; Klebsiella aerogenes; Candida utilis; Gibbs energy of biosynthesis; Bi-osynthesis reaction; Enthalpy; Entropy; Pathogen-host interaction
LIFE SCIENCES, Virology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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