REVIEW
|
doi:10.20944/preprints202404.0203.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
cold plasma; plasma-activated water; redox signalling; cancer; wound healing; Nrf2; MAPK; PI3K/Akt; endoplasmic reticulum stress
Online: 2 April 2024 (12:22:07 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0806.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
ODZ1; EGFR; glioblastoma; migration; p38 MAPK
Online: 14 March 2024 (11:11:25 CET)
ARTICLE
|
doi:10.20944/preprints202402.0866.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
cancer; PI3K; HDAC6; cytotoxicity; antiproliferative; synergism; DMPK
Online: 15 February 2024 (15:35:47 CET)
ARTICLE
|
doi:10.20944/preprints202402.0640.v1
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
Lung adenocarcinoma; EGFR TKI; precision oncology; in silico; computational oncology
Online: 12 February 2024 (10:57:20 CET)
REVIEW
|
doi:10.20944/preprints202402.0609.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Lung NETs, neuroendocrine tumors, typical carcinoid, atypical carcinoid, pulmonary NETs, EGFR, DLL3, immunotherapy
Online: 12 February 2024 (09:53:33 CET)
ARTICLE
|
doi:10.20944/preprints202402.0503.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
HNSCC; PI3K inhibitors; ErbB inhibitor; targeted therapy
Online: 8 February 2024 (14:11:24 CET)
REVIEW
|
doi:10.20944/preprints202401.1992.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
MLIP; Cancer; PI3 kinase; Akt; mTOR; Tumorigenesis
Online: 29 January 2024 (05:47:34 CET)
REVIEW
|
doi:10.20944/preprints202312.1388.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Rheb1; Rheb2; Cancer; mTOR; Hallmarks; Neurons; Rheb1 inhibitors
Online: 19 December 2023 (05:58:46 CET)
ARTICLE
|
doi:10.20944/preprints202312.1030.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Marrow failure; mitochondria; SRSF4; mTOR; CLUH; DRP1; OPA1
Online: 14 December 2023 (08:07:53 CET)
ARTICLE
|
doi:10.20944/preprints202312.0748.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
monoclonal antibody; EGFR; tumor-targeting; pharmacokinetics; radionuclide-based biodistribution; nanoSPECT/CT
Online: 12 December 2023 (05:11:26 CET)
ARTICLE
|
doi:10.20944/preprints202311.0851.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Estrogen receptor a; sigma receptors; TMEM97; mTOR; S6K1; tamoxifen.
Online: 14 November 2023 (09:28:12 CET)
ARTICLE
|
doi:10.20944/preprints202311.0013.v1
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
Bisphenol A; Bisphenol S; Bisphenol F; Atopic dermatitis; DNA methylation; JAK-STAT signaling pathway; PI3K-AKT signaling pathway
Online: 1 November 2023 (04:02:06 CET)
ARTICLE
|
doi:10.20944/preprints202310.1726.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
dacomitinib; EGFR inhibitor; overall survival; pharmacokinetics; progression-free survival; proton pump inhibitors
Online: 27 October 2023 (07:06:07 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1581.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
renal age-related decline; kidney disease (KD); eGFR; mGPS
Online: 25 October 2023 (08:35:43 CEST)
REVIEW
|
doi:10.20944/preprints202310.1483.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
AR; TNBC; CDK4/6; CYP17 lyase; PI3K/AKT; ER; PR; HER2; DHT
Online: 24 October 2023 (05:51:15 CEST)
REVIEW
|
doi:10.20944/preprints202310.1203.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
cancer; microRNA; AKT3; AKT signaling; small non-coding RNAs; circRNA; lncRNA; epigenetic regulation
Online: 19 October 2023 (05:08:12 CEST)
ARTICLE
|
doi:10.20944/preprints202310.0878.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
AKT; cold atmospheric plasma; ERK; miRNA; oral carcinoma
Online: 13 October 2023 (10:04:03 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1706.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
isoxazolidine derivatives; 1,3-dipolar cycloaddition; α-aryl-N-methyl nitrones; Density Functional Theory (DFT); Electron Localization Function (ELF); CDFT indices; docking; molecular dynamics; EGFR; binding energy
Online: 26 September 2023 (04:37:56 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1949.v2
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
Methamphetamine; BDNF; CREB; Akt-1; GSK3; Amygdala
Online: 20 September 2023 (03:22:53 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1214.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
renal dysfunction; chronic kidney disease; CKD-stage; eGFR; creatinine; cystatin C
Online: 18 September 2023 (16:13:29 CEST)
REVIEW
|
doi:10.20944/preprints202309.0682.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Akt; cancer; metastasis; HNSCC; EMT; cytoskeletal remodelling
Online: 12 September 2023 (08:33:01 CEST)
REVIEW
|
doi:10.20944/preprints202309.0633.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
metastatic hormone-sensitive prostate cancer; new hormonal agents; transcriptomic profiling; DNA damage repair genes; tumor suppressor genes; androgen receptor; immunotherapy; CDK4/6 inhibitors; PARP inhibitors; AKT inhibitors.
Online: 11 September 2023 (07:17:07 CEST)
REVIEW
|
doi:10.20944/preprints202309.0571.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
immunotherapy, EGFR mutation, non-small cell lung cancer
Online: 8 September 2023 (09:51:50 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1752.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Intracerebroventricular, ICV; mTOR, mTOR-I, rapalog; Tuberous Sclerosis, TSC; Multiple Sclerosis, MS; Experimental Autoimmune Encephalitis, EAE; Alzheimer’s Disease, AD; Thermostable Micelles, Micellar Liquid Formulation; Ommaya device
Online: 24 August 2023 (12:53:26 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1446.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
UMOD; CKD; Creatinine; Urea; eGFR; Uromodulin; Genotyping; ARMS-PCR
Online: 22 August 2023 (02:34:34 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0796.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
anesthesia neurotoxicity; neuropathic pain; neural activity; mammalian target of rapamycin (mTOR); dorsal spinal cord (DSC), dorsal root ganglion (DRG).
Online: 10 August 2023 (08:17:30 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0641.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
licochalcone H (LCH); oxaliplatin; colorectal cancer; EGFR; AKT; apoptosis
Online: 9 August 2023 (03:01:44 CEST)
REVIEW
|
doi:10.20944/preprints202308.0444.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Avenanthramide; AKT-Protein kinase B; Alzheimer's disease; Parkinson's disease; oxidative stress; neuroprotection
Online: 7 August 2023 (02:28:52 CEST)
REVIEW
|
doi:10.20944/preprints202307.1695.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
hepatocellular carcinoma; EGFR/PI3K/AKT/mTOR signaling; animal models; Targeted Therapy
Online: 26 July 2023 (10:07:16 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1464.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
bovine skeletal muscle satellite cells; sodium butyrate; mitophagy; apoptosis; mTOR signaling pathway
Online: 21 July 2023 (05:18:58 CEST)
REVIEW
|
doi:10.20944/preprints202307.1284.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Cancer; tumourigenesis; drug resistance; signalling pathways; Wnt/β-catenin pathway; JAK/STAT pathway; PI3K/Akt/mTOR pathway; RAS/RAF/MAPK/ERK signalling
Online: 19 July 2023 (09:14:02 CEST)
REVIEW
|
doi:10.20944/preprints202307.0552.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer chemotherapy; transmembrane receptors; EGFR; targeted protein degradation; furfuryl-quinolin-triazole-thiol chemicals
Online: 10 July 2023 (07:23:13 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1949.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
homocysteine thiolactone; N-homocysteinylated protein; microRNA; PHF8; mTOR; autophagy; endothelial cells
Online: 28 June 2023 (07:08:26 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202306.1357.v1
Subject:
Medicine And Pharmacology,
Reproductive Medicine
Keywords:
mTOR; rapamycin; PRP; platelet cytokines; ovarian reserve; IVF
Online: 19 June 2023 (12:55:06 CEST)
REVIEW
|
doi:10.20944/preprints202306.1251.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
mTOR; gut microbes; metabolites; therapy
Online: 16 June 2023 (14:02:23 CEST)
REVIEW
|
doi:10.20944/preprints202306.0952.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
mTOR; CD8 T cell; NK cell; cytokine signaling
Online: 13 June 2023 (15:45:23 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0313.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Liquid biopsy; EGFR; NSCLC; T790M mutation; NGS; PCR
Online: 5 June 2023 (11:06:11 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0050.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
ASD; autism; autistic spectrum disease; NSE; Neuron-specific enolase; autism biomarker; neuroinflammation; neuronal apoptosis; mTOR
Online: 1 June 2023 (07:30:35 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1857.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
γH2AX; Actinomycin D; Akt; DNA damage response; DNA double-strand break; DNA-PK; Etoposide; p95/NBS1
Online: 26 May 2023 (05:11:01 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1804.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
EVs; Macrophages 1; STAT3, AKT; NF-κB; metastasis; colorectal cancer.
Online: 25 May 2023 (10:48:17 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1194.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Breast cancer; obesity; metabolic syndrome; rat model; DMBA; insulin signaling; PI3/Akt
Online: 17 May 2023 (05:25:25 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0844.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Peptidomimetic; VEGFR2; Angiogenesis; Tumor suppression; PI3K/Akt/mTOR signaling pathway; PLCγ/ERK signaling pathway
Online: 11 May 2023 (10:57:38 CEST)
COMMUNICATION
|
doi:10.20944/preprints202305.0641.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
mouse EGFR; monoclonal antibody; Cell-Based Immunization and Screening; CBIS
Online: 9 May 2023 (10:42:31 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0406.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Biosensors; ultra-short circulating tumor DNA; Lung Cancer; Liquid biopsy; EGFR
Online: 6 May 2023 (09:44:49 CEST)
REVIEW
|
doi:10.20944/preprints202305.0122.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Non-small cell lung cancer (NSCLC); EGFR; Tyrosine kinase inhibitors (TKIs); Uncommon mutation; Compound mutation; Intracranial activity; Immunotherapy
Online: 3 May 2023 (09:29:08 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0797.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Heart failure; Malnutrition; Exercise; Amino-acids; mTOR; Deptor
Online: 23 April 2023 (08:45:26 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0254.v1
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
cancer cells; quinones; mTOR; antiproliferative activity; molecular descriptors; molecular docking
Online: 12 April 2023 (07:57:34 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0250.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
AI drug discovery; mTOR; rapalog; C. elegans; cancer; longevity
Online: 15 February 2023 (02:42:57 CET)
ARTICLE
|
doi:10.20944/preprints202301.0585.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
glioblastoma; cancer stem cells; EMT; MGMT; temozolomide; doxorubicin; STAT3; EGFR inhibitor (AG1478)
Online: 31 January 2023 (12:01:04 CET)
ARTICLE
|
doi:10.20944/preprints202301.0129.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
chondrogenesis; cartilage; col11a1; collagen α1(XI), AKT; GSK3b; Wnt; ATDC5
Online: 7 January 2023 (13:00:05 CET)
ARTICLE
|
doi:10.20944/preprints202212.0331.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SMN; RNA-binding proteins; head and neck cancers; squamous cell carcinoma; EGFR
Online: 19 December 2022 (09:02:58 CET)
ARTICLE
|
doi:10.20944/preprints202212.0011.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
MST4; EMT; AKT; Apoptosis; Breast cancer
Online: 1 December 2022 (04:46:12 CET)
ARTICLE
|
doi:10.20944/preprints202211.0200.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
neutropenia; neutropenic fever; chemotherapy; kidney function impairment; mild kidney disease; eGFR; CKD-EPI; G-CSF; Kaplan-Meier curves; survival analysis
Online: 10 November 2022 (11:11:40 CET)
REVIEW
|
doi:10.20944/preprints202210.0230.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
PBDE; dose-response relationships; mTOR signaling; steroidogenesis; metabolic disruption; sperm epigenome
Online: 17 October 2022 (05:37:53 CEST)
ARTICLE
|
doi:10.20944/preprints202210.0028.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
EGFR; HER2; bispecific antibody; ADCC; CDC; canine osteosarcoma
Online: 5 October 2022 (09:45:16 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0042.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Colorectal cancer; ddPCR; KRAS; NRAS; BRAF; EGFR
Online: 5 May 2022 (15:24:14 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0001.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
CMT1E; Trembler-J; curcumin; Hsps; autophagy; mTOR
Online: 1 March 2022 (02:52:34 CET)
REVIEW
|
doi:10.20944/preprints202112.0518.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
B-cell non-Hodgkin lymphoma (B-NHL); B-cell receptor (BCR); Bruton’s tyrosine kinase (BTK); spleen tyrosine kinase (SYK); phosphoinositide-3-kinase (PI3K); ibrutinib; acalabrutinib; copanlisib; idelalisib; umbralisib; fostamatinib; combination therapies
Online: 31 December 2021 (12:23:29 CET)
ARTICLE
|
doi:10.20944/preprints202112.0023.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Cancer; neurodegeneration; glioma; Drosophila; disease model; PI3K; EGFR; genetics
Online: 2 December 2021 (09:30:17 CET)
COMMUNICATION
|
doi:10.20944/preprints202111.0052.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
RNA-based NGS; EGFR mutated NSCLC; acquired resistance; RET-fusion; rebiopsy
Online: 2 November 2021 (22:19:36 CET)
HYPOTHESIS
|
doi:10.20944/preprints202110.0373.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Zika virus; Microcephaly; Neurogenesis; Retinoic Acid; mTOR signaling
Online: 26 October 2021 (11:12:37 CEST)
ARTICLE
|
doi:10.20944/preprints202110.0003.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
AP5M1; BAIAP2L1; ENTPD2; MTOR; AKT2; FKBP9; TBRG4; TMEM186
Online: 1 October 2021 (11:16:39 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Vericiguat; osteoclast (OCs), MAPK, NF-κB; RANKL; AKT, molecular mechanism
Online: 8 September 2021 (13:02:05 CEST)
REVIEW
|
doi:10.20944/preprints202108.0552.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
antagonistic pleiotropy; insulin/IGF-1 signalling; hyperfunction; quasi-programs; mTOR; theories of aging; programmatic aging
Online: 30 August 2021 (16:11:02 CEST)
REVIEW
|
doi:10.20944/preprints202107.0353.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Lung cancer; Adjuvant treatment; Non-small-cell lung carcinoma (NSCLC); Epidermal growth factor receptor (EGFR); Tyrosine kinase inhibitor (TKI)
Online: 15 July 2021 (10:16:30 CEST)
REVIEW
|
doi:10.20944/preprints202106.0333.v2
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
2-Deoxyglucose; Adverse effects; COVID-19; Glutamine; PI3K/Akt
Online: 1 July 2021 (13:04:43 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0443.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
miR-378d; ESCC; AKT; RhoA; polyploidization
Online: 16 June 2021 (12:07:30 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0169.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
melanoma initiating cells; CD133; drug resistance; apoptosis; caspase activation; CRISPR-Cas9 knockout; AKT; BAD; BCL-2 family
Online: 7 June 2021 (12:11:10 CEST)
REVIEW
|
doi:10.20944/preprints202105.0367.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
PI3K/mTOR signalling; feedback loop; crosstalk; nonlinear dynamics; cancer
Online: 17 May 2021 (07:54:13 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0732.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Epidermal Growth Factor Receptor (EGFR); mutations, EGFR tyrosine kinase inhibitor; molecular epidemiology; Non-small-cell lung cancer
Online: 28 April 2021 (07:55:22 CEST)
REVIEW
|
doi:10.20944/preprints202104.0379.v1
Subject:
Social Sciences,
Psychology
Keywords:
Substantia nigra; mTOR; SUMO E3 ligase; Huntington’s disease; 3,4-methylenedioxymethamphetamine (MDMA); autophagy; L-Dopa-induced dyskinesia (LID); mitophagy
Online: 14 April 2021 (13:41:05 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0687.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
gold nanorods; targeted; EGFR; HNSCC; uptake; NIR-II window
Online: 29 March 2021 (12:11:26 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Metformin; cerebralischemia-reperfusion; inflammation; PI3K/Akt.
Online: 12 March 2021 (08:43:06 CET)
REVIEW
|
doi:10.20944/preprints202102.0278.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
ncRNA; miR; NCDs; onco-miR; cancer; mTOR
Online: 11 February 2021 (11:04:50 CET)
ARTICLE
|
doi:10.20944/preprints202101.0232.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
CaSR; Homer1; mTOR; osteoblast; osteocyte; AKT; chaperone function
Online: 12 January 2021 (17:21:02 CET)
REVIEW
|
doi:10.20944/preprints202101.0120.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
mTOR; ATP; protein synthesis; autophagy; amino acids; nutrition; adipose tissue; muscle; sarcopenia; mitochondria
Online: 6 January 2021 (14:32:22 CET)
REVIEW
|
doi:10.20944/preprints202012.0675.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Breast cancer; Estrogen Receptor; PI3K-AKT-mTOR; anti-estrogen resistance
Online: 28 December 2020 (09:22:17 CET)
REVIEW
|
doi:10.20944/preprints202010.0195.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Autophagy; Amyloid precursor protein (APP); β‐amyloid (Aβ); mTOR; Alzheimer’s disease (AD).
Online: 9 October 2020 (11:07:53 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0572.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
glycine soja seed; type 2 diabetes mellitus; antidiabetic; AMPK; Akt; PPAR-γ
Online: 26 August 2020 (09:16:38 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Glycine soja seed; Type 2 diabetes mellitus; Antidiabetic; AMPK; Akt; PPAR-γ
Online: 25 August 2020 (11:47:20 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0112.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
AKT/PI3K signaling pathway; apoptosis; human hepatocarcinoma HepG2 cells; migration activity; proliferation; oxidative stress; ROS level; uvaol
Online: 5 August 2020 (05:58:26 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0527.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Triple Negative Breast Cancer; Cancer Stem Cell; Hypoxia; EGFR; Cisplatin; PDX
Online: 22 July 2020 (11:32:30 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0514.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
AKT; D-Pinitol; ghrelin; insulin; insulin resistance; liver; phosphorylation
Online: 31 May 2020 (21:11:01 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0445.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
oral cancer; cancer-associated fibroblasts; metastasis; cell migration; cell invasion; Akt; EGFR
Online: 27 May 2020 (08:25:20 CEST)
REVIEW
|
doi:10.20944/preprints202004.0530.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
CDK1; eIF4F; mTOR; mRNA translation; M-phase
Online: 30 April 2020 (13:46:44 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0312.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
chalocomoracin; proliferative vitreoretinopathy; vitreous; Akt; p53; migration; proliferation; contraction
Online: 19 April 2020 (02:18:01 CEST)
REVIEW
|
doi:10.20944/preprints202004.0060.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
COVID-19; coronavirus; cytokine storm; immunity; ADE; cross-reactive antibody; rapamycin; mTOR inhibotors
Online: 6 April 2020 (14:03:00 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0053.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
calcium signaling; chemokine signaling; gap junction; NOD-like receptor signaling; oli-neu cells; pannexin1; PI3K-Akt pathway; thyroid hormone pathway
Online: 6 April 2020 (12:36:20 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0255.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Cordycepin; Cisplatin-resistance; Resensitization; MDR1; Ets-1; AKT
Online: 22 January 2020 (09:18:20 CET)
ARTICLE
|
doi:10.20944/preprints202001.0109.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Alzheimer’s disease; curcumin; network pharmacology; molecular simulation; neurodegeneration; TrkB/PI3K signaling; autophagy
Online: 11 January 2020 (13:53:12 CET)
ARTICLE
|
doi:10.20944/preprints201912.0382.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
glioblastoma multiforme; MGMT; IDH1; EGFR; P53; ATRX; Ki67; neurosurgery; oncology; epilepsy
Online: 29 December 2019 (13:04:12 CET)
REVIEW
|
doi:10.20944/preprints201911.0170.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
PI3K signalling; cancer; stemness; pluripotent stem cells; development
Online: 15 November 2019 (03:59:00 CET)
ARTICLE
|
doi:10.20944/preprints201910.0180.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
long term survival; Glioblastoma; IDH; EGFR; Ki67; p53
Online: 16 October 2019 (08:30:25 CEST)
ARTICLE
|
doi:10.20944/preprints201909.0037.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
EGFR; ErbB3; Src; phosphorylation; TK inhibitor; cetuximab
Online: 4 September 2019 (03:21:39 CEST)
REVIEW
|
doi:10.20944/preprints201907.0256.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
PI 3-kinase; chromosomal instability; PI3K inhibitor; cancer; tumour evolution; centrosome
Online: 23 July 2019 (11:01:34 CEST)
REVIEW
|
doi:10.20944/preprints201905.0358.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
alloimmune response; immunosuppressants; calcineurin inhibitors; corticosteroids; mTOR inhibitors; neurotoxicity; neuroprotective effects
Online: 29 May 2019 (16:37:44 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
EGFR-mutated non-small cell lung cancer; EGFR-TKI; intrinsic resistance; resistance mechanisms
Online: 22 April 2019 (11:08:42 CEST)
REVIEW
|
doi:10.20944/preprints201904.0127.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
PTEN; PI3K; cancer predisposition syndromes; targeted therapies; mouse models of human cancer
Online: 10 April 2019 (10:37:43 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
cysteine oxidation redox systems biology proteomics signaling EGFR cryptic
Online: 10 April 2019 (10:07:12 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
KIT assay; chronic kidney disease; biomarker; non-invasive; urine; eGFR; cfDNA
Online: 20 March 2019 (02:12:19 CET)