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Preprint ARTICLE | doi:10.20944/preprints202309.1761.v1

Design, Implementation and Evaluation of an Innovative Pilot Intervention to Improve the Quality of Life of the Family of Students with Specific Learning Disabilities. A Quantitative Analysis

Nektaria Pedioti, Stavroula Lioliou, Katerina Koutra, Stavros Parlalis, Maria Papadakaki

Subject: Public Health And Healthcare, Primary Health Care Keywords: specific learning disabilities; children; parenting; authoritarian; intervention; quality of life; experimental design

Online: 26 September 2023 (11:55:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1503.v1

Hypertrophic Cardiomyopathy in Underrepresented Populations: Clinical and Genetic Landscape Based on Russian Single-Center Cohort Study

Olga S. Chumakova, Tatiana N. Baklanova, Natalia V. Milovanova, Dmitry A. Zateyshchikov

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: hypertrophic cardiomyopathy; Russian; Slavic; underrepresented population; specific characteristics; genetics; MYBPC3; MYH7; TPM1; FLNC

Online: 22 September 2023 (05:31:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1349.v1

Incorporation of Functionalized Amino Acid Ionic Liquid into Highly Porous MOF-177 to Improve Post-Combustion CO₂ Capture Capacity

Firuz A. Philip, Amr Henni

Subject: Engineering, Chemical Engineering Keywords: CO2 Capture; Metal Organic Framework (MOF); Ionic Liquid; Amino Acid Ionic Liquid (AAILs); Task-Specific Ionic Liquid (TSIL); MOF-177

Online: 20 September 2023 (10:40:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1364.v1

Development of a Site-Specific Management Strategy for Managing Root-Knot Nematodes Affecting Tomatoes in Kenya

philip Wendot, Francis Kariuki, George Ngundo, Jonah Birgen, George Kariuki

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Tomato; Root-knot nematodes; Site-specific farming; Mwea, Kenya

Online: 20 September 2023 (07:13:05 CEST)

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Tomato (Solanum lycopersicum L.) is a high value horticultural crop in Kenya. Nutritionally, the crop is rich in niacin, carotene, thiamine, and vitamin C. Mwea in Kirinyaga County is one of the major tomato growing areas in Kenya. Tomato production in Kenya is hindered by losses due to diseases caused by pathogens that include plant parasitic nematodes (PPN). Among the plant parasitic nematodes, the root-knot nematode (RKN) is the most predominant in Mwea. This study investigated the soil parameters that influence the distribution of the RKN for the purpose of mapping their distribution. This is important since it ensures that nematicide application is only to specific sites where these nematodes are found thereby saving on input costs as well as protecting the environment. The study consisted of surveys conducted in geo-referenced tomato production fields in seven (7) tomato production sites in Tebere and Mwea. Sampling was done in a stratified random manner in both rainfed and irrigated tomato production fields in both dry and rainy seasons for determination of the spatial and temporal distribution of nematodes, respectively. Nematode extraction was done using the centrifugal floatation technique and identification done to genera level using morphological features. Soil characteristics determining PPN distribution patterns in tomato production fields of Mwea were measured using standard methods. Soil parameters measured included soil pH, electrical conductivity, elevation and soil texture. The PPN incidence and diversity was determined using the Shannon-Weiner species diversity index. Detrended canonical correspondence analysis (DCCA) was performed to interpret and summarize major patterns of variation within the soil variable data and to estimate the ability of each soil variable to reflect variance in the entire PPN data set. Fourteen (14) genera of nematodes were identified with the diversity between 0.6 and 1.2. RKN distribution differed significantly (p<0.05) among the sites. Among the soil samples analyzed, 81% were positive for RKN infestation. There was an insignificant difference (p>0.05) between nematode densities in the dry and rainy seasons. Rainfed fields exhibited a significantly higher (p<0.05) RKN population densities compared to irrigated fields. The study established a great variability in the soil parameters in the area. The RKN distribution pattern, density and abundance were inversely correlated (p<0.05) with the soil pH and positively correlated (p<0.05) with soil EC. Based on the inverse relationship between soil pH and RKN distribution in the Mwea ecosystem, maps of nematode distribution and soil pH were developed. This enables the possibility of a site specific system for management of RKN

Preprint ARTICLE | doi:10.20944/preprints202309.0859.v1

The Novel Tetra-specific Drug C-192, Conjugated Using UniStac, Alleviates Non-alcoholic Steatosis Hepatitis in MCD Diet-induced Mouse Model

Ji-Hye Kim, Nakho Chang, Yunki Kim, Jaehyun Lee, Daeseok Oh, Jaeyoung Choi, Onyou Kim, Su-Jin Kim, Myongho Choi, Junyeob Lee, Junghwa Lee, Jungyul Kim, Minji Cho, Minsu Kim, KwangHwan Lee, Dukhyun Hwang, Jason K. Sa, Sungjin Park, Seungjae Baek, Daeseong Im

Subject: Chemistry And Materials Science, Biomaterials Keywords: multi-specific; conjugation; platform; complex disease; NASH; GLP-1; GCG; FGF21; IL-1RA; chronic inflammation

Online: 13 September 2023 (09:36:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0697.v1

Theoretical Validation and Hardware Implementation of Dynamic Adaptive Scheduling for Heterogeneous Systems-on-Chip

A. Alper Goksoy, Sahil Hassan, Anish Krishnakumar, Radu Marculescu, Ali Akoglu, Umit Y. Ogras

Subject: Computer Science And Mathematics, Hardware And Architecture Keywords: domain-specific SoC (DSSoC); task scheduling; runtime classification; policy switching

Online: 12 September 2023 (04:41:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0688.v1

Comparative Study of the Physico-Chemical Properties of Sorbents Based on Natural Bentonites Modified with Iron (III) and Aluminium (III) Polyhydroxocations

Bakytgul Kussainova, Gaukhar Tazhkenova, Rabiga Kudaibergenova, Ivan Kazarinov, Anna Lamichova, Aisha Nurlybayeva, Lyazat Kusepova, Togzhan Mashan, Batima Tantybayeva, Bekzat Saurbayeva

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: bentonite sorbent; sorption of nickel (II) cations; specific surface area; polyhydroxocation; "co-precipitation" method

Online: 12 September 2023 (03:06:31 CEST)

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A comparative study of the physicochemical properties of natural bentonite clays of Pogodayevо (Republic of Kazakhstan, mod.1) and Dash-Salakhli (Republic of Azerbaijan, mod.2) deposits and modification of the bentonite clay with polyhydroxocations of iron (III) and aluminium (III). It-wasestablished that the modification of natural bentonitesusing polyhydroxocations of iron (III) and aluminium(III) by the method of "co-precipitation" leads to a change in their chemical composition, structural and sorption properties. The results showed that hydroxy-aluminum cations ([Al3O4(OH)24(H2O)12]7+) and poly-hydroxyl-Fe or polyoxo-Fe were intercalated into clay layers, which led to an increase in the values of d001 and specific surface areas compared to those of the original bentonite, from 37 to 120 for the Pogodaevo bentonite and from 51 to 172 respectively for bentonite from the Dash-Salakhli deposit. It is shown that modified sorbents based on natural bentonite are finely porous objects with a predominance of pores of 1.5−6.0 nm in size. As a result, there is a significant increase in the specific surface area of sorbents. Modification of bentonite with polyhydroxocations of iron (III) and aluminium (III) by the "co-precipitation" method also leads to an increase in the sorption capacity of the sorbents obtained with respect to nickel (II) cations. Modified bentonites were used for the adsorption of Ni (II) ions from the model solution. Ni (II) was absorbed in a neutral pH solution. The study of equilibrium adsorption showed that the data are in good agreement with the Langmuir isotherm model. The maximum adsorption capacity of the Ni (II) monolayer obtained from the Langmuir equation was 25.0 mg/g (mod. 1_Al_5-c), 18.2 mg/g (mod. 2_Al_5-c) for Al-bentonite and 16.7 mg/g (mod. 1_Fe_5-c), 10.1 (mod. 2_Fe_5-c) for Fe-bentonite. The kinetics of adsorption is considered. The high content of Al-OH anion exchange centresin them determines the higher sorption activity of Al-modified bentonites.

Preprint ARTICLE | doi:10.20944/preprints202309.0646.v1

Pacing Strategy of 800-Meter and 1500-Meter Freestyle Swimming Finals in the World Championships According to the Performance in Males and Females of Different Age Groups

Sabrina Demarie, Jean Renaud Pycke, Alessia Pizzuti, Veronique Billat

Subject: Biology And Life Sciences, Other Keywords: energy cost; endurance; training; technique; tactic; fatigue; performance; time series; mathematical modelling; sex difference

Online: 11 September 2023 (14:45:18 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.0563.v1

Sex, Age, and Risk Groups Variations among Individuals Infected with HIV, HTLV-1, and HTLV-2: Review of Data Records (1983–2017) from a Public Health Laboratory in São Paulo, Brazil

Adele Caterino-de-Araujo

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: HIV; HTLV-1; HTLV-2; sex; risk factors; prevalence; co-infection; public policies

Online: 8 September 2023 (09:39:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0546.v1

Patient-Specific 3D Virtual Surgical Planning using Simulated Fluoroscopic Images to Improve Sacroiliac Joint Fusion

Nick Kampkuiper, Jorm Nellensteijn, Edsko Hekman, Gabriëlle Tuijthof, Steven Lankheet, Maaike Koenrades, Femke Schröder

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: Sacroiliac joint dysfunction; Sacroiliac joint fusion; Minimally invasive surgery; Virtual surgical planning; Simulated fluoroscopic images; Implant placement accuracy; Patient-specific modeling

Online: 7 September 2023 (10:44:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0307.v1

Testing and Evaluation of Cervical Joint in Young Males and Females: Strength, Range of Motion and Musculoskeletal Pains

Christos Batatolis, Konstantina Karatrantou, Vaggelis Gymnopoulos, Dr. Vassilis Gerodimos

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: neck; isometric assessment; hand‐held dynamometer; functional capacity; cervical flexion/extension ratio; injury prevention; strength asymmetries; rehabilitation; sex effect

Online: 6 September 2023 (04:27:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.2078.v1

The Role of Strength-Related Factors on Psychological Readiness for Return to Sport following Anterior Cruciate Ligament (ACL) Reconstruction

Oliver Lee, Mark A Williams, Clare D Shaw, Anne Delextrat

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: angle-specific torque; rate of force development; time since surgery; rehabilitation

Online: 30 August 2023 (11:19:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1828.v1

Engineered Expression of the Vip3A in Green Tissues as a Feasible approach for Control of Insect Pests in Maize

Guangsheng Yuan, Cheng Zeng, Haoya Shi, Yong Yang, Juan Du, Chaoying Zou, Langlang Ma, Guangtang Pan, Yaou Shen

Subject: Engineering, Safety, Risk, Reliability And Quality Keywords: genetically modified; Cre/loxP; site-specific excision; transgenic maize; insect-resistance

Online: 28 August 2023 (08:48:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1690.v1

Patient Specific Instrumentation with Laser Guide Navigated THA: Clinical and CT Evaluation of the First 100 Cases

Leonardo Previ, Edoardo Viglietta, Veronica Giuliani, Federico Corsetti, Andrea Redler, Attilio Speranza, Angelo De Carli, Raffaele Iorio

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: hip-spine; planning; THA; patient-specific

Online: 24 August 2023 (04:01:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1697.v1

Exergy Loss Assessment Method for CNC Milling System considering the Energy Consumption of the Operator

Zhaohui Feng, Hua Zhang, Yajian Yu, Youjia Guan, Xinru Ding, Wei Li

Subject: Engineering, Mechanical Engineering Keywords: CNC milling system; the energy consumption of the operator; exergy analysis; the specific exergy loss

Online: 24 August 2023 (03:25:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1132.v1

Immunological Misfiring and Sex Differences/Similarities in Early COVID-19 Studies: Missed Opportunities of Making a Real IMPACT

Aditi Bhargava, Johannes D Knapp

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: coagulopathy; COVID-19; CXCL; dendritic cells; ICU; IL6; IL7; IFN; sex differences and similarities

Online: 16 August 2023 (07:57:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0878.v1

Usp22 Deficiency Switches Antiviral Response into Pathological CD8+ T Cell Activation via Downregulation of PD-L1

Justa Friebus-Kardash, Theresa Charlotte Christ, Nikolaus Dietlein, Abdelrahman Elwy, Hossam Abdelrahman, Lisa Holnsteiner, Zhongwen Hu, Hans-Reimer Rodewald3, Karl Sebastian Lang

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Ubiquitin-Specific-peptidase 22 (Usp22); LCMV; PD-L1 downregulation; activation of CD8+ T cells; iver failure

Online: 11 August 2023 (08:58:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0711.v1

Young Women’s Attitudes and Concerns on Pornography and Their Sexual Experiences: A Qualitative Approach

Mónica Fernández-Ruiz, Olga María López-Entrambasaguas, Jose Manuel Martínez-Linares, José Granero-Molina

Subject: Public Health And Healthcare, Primary Health Care Keywords: pornography; qualitative research; sexual behavior; sex education; sexual health; young women

Online: 9 August 2023 (09:05:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0560.v1

Energy Efficiency and Environmental Benefits of Waste Heat Recovery Technologies in Fishmeal Production Plants: A Case Study in Vietnam

Tra Van Tung, Nguyen Thi To Nga, Huu Tap Van, Tran Hai Vu, Ksawery Kuligowski, Adam Cenian, Nguyen Quang Tuan, Phuoc-Cuong Le, Quoc Ba Tran

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: waste heat recovery technologies; specific energy consumption (SEC),; fish meal production; , energy efficiency practices; environmental sustainability

Online: 8 August 2023 (11:09:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0627.v1

Multicentric Study from Southern Italy Hospitals on Oncological Outcomes and Prognostic Factors of Open Partial Horizontal Laryngectomies (OPHL) for Laryngeal Cancer

Eugenia Allegra, Maria Rita Bianco, Domenico Michele Modica, Alfio Azzolina, Elio Privitera, Daniele Latella, Federico Occhiuzzi, Mario Galfano, Vincenzo Saita

Subject: Medicine And Pharmacology, Otolaryngology Keywords: open partial horizontal laryngectomy; laryngeal cancer; laryngeal preservation; laryngectomy free survival; disease specific survival; total laryngectomy

Online: 8 August 2023 (10:25:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0468.v1

Pharmacokinetics of Four Tyrosine Kinase Inhibitors in Adult and Paediatric Chronic Myeloid Leukaemia Patients

Sarah Allegra, Emma Dondi, Francesco Chiara, Silvia De Francia

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: dasatinib; imatinib; nilotibin; ponatinib; children; therapeutic drug monitoring; sex and gender pharmacology; personalized medicine.

Online: 7 August 2023 (11:53:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0536.v1

Serum Specific Immunoglubulin E: Major Determinant for Accessing Sensitivity for Various Pediatric Allergies in North India

Swati Gupta, Rajiv Kumar Gupta, Vigyan Mishra, Hridayesh Prakash

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Pediatric Allergy. Specific IgE; Skin prick test; allergens

Online: 7 August 2023 (10:46:46 CEST)

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High prevalence of allergic disorders in Indian pediatric patients demands early diagnosis of allergens so that appropriate allergen avoidance methods, pharmacotherapy or immunotherapy can be provided in time to avoid the worsening of symptoms due to triggers. In this context, identification of the most prevalent aeroallergens in a given area is critical for diagnosis and treatment of various allergic reactions especially in case of rhino-conjunctivitis and asthma. The specific diagnosis of IgE mediated allergy is usually based on the correlation between the clinical history and signs and symptoms endorsed by the diagnostic tests. Skin prick tests are the gold standard however has some limitation. In view of this, the aim of this study was to assess the significance of ImmunoCAP assay for assessing serum specific IgE levels, available in India, against skin prick test by standardized allergens, for the diagnosis of allergic sensitization. A single-center observational study was conducted at tertiary care corporate hospitals in North India from 2017-2020. Patients with self-reported allergic symptoms or whose symptoms were suspected for allergies were tested for the type of sensitization using skin prick test (SPT) after their consents followed by ImmunoCAP based quantification of serum specific IgE levels. A total of 256 (95.9%) pediatric patients were analyzed in the study and were analysed. The patients were most commonly (30% patients) sensitized to D. farinae (173 [67.6%]), D. pteronyssinus (174 [68.0%]), Acarus siro (93 [36.3%]), Lepidoglyphus destructor (96 [37.5%]), Plantago lanceolata (Engl.). The ROC curve of Bermuda grass shows that the AUC of serum-specific IgE is larger than that of SPT (1.000 / 0.881). The receiver operating characteristic (ROC) analysis of serum-specific IgE reference method resulted in the largest AUC of all the allergens taken into consideration (0.711 / 1.000) compared to those of SPT (0.589 / 1.000). These results revealed that serum-specific IgE is more reliable method over prick test for accessing the sensitivity of patient for various allergens. This study may be helpful in performing early diagnosis of allergies as well as in taking appropriate preventive measures for managing life threatening allergic reactions

Preprint ARTICLE | doi:10.20944/preprints202308.0107.v1

Application of the Compound Specific Stable Isotopes (CSSI) technique to evaluate the contributions of sediment sources in the Panama Canal Watershed

José Peralta, Lucas Calvo, Reinaldo Gil, Yanna Llerena, Kathia Broce, Ana Franco, Jacinto Cherigo

Subject: Environmental And Earth Sciences, Soil Science Keywords: Nuclear technique, Compound Specific Stable Isotopes (CSSI), Sedimentation, Water Reservoir, Panama Canal Watershed

Online: 2 August 2023 (08:21:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0053.v1

Evaluation of Equine Fecal Egg Count Tests for Accurate Monitoring of Anthelmintic Resistance

Manigandan Lejeune, Sabine Mann, Holly White, Danielle Maguire, Jaime Hazard, Rebecca Young, Charles Stone, Doug Antczak, Dwight Bowman

Subject: Biology And Life Sciences, Parasitology Keywords: Equine strongyle; Fecal Egg Count; FEC; modified McMaster; Mini-FLOTAC; Wisconsin floatation; sugar 1.33 specific gravity; NaNO3 1.33 specific gravity; NaCl 1.20 specific gravity; ZnSO4 1.18 specific gravity; AAEP; anthelmintic resistance; FEC gold standard

Online: 1 August 2023 (10:32:58 CEST)

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Parasite control strategies such as blanket anthelmintic treatment of all horses in a herd or interval treatment regimen based on egg reappearance remain widely followed practices for the last several decades. These practices have resulted in the fast emergence of resistance in equine strongyles to all major classes of drugs on the market. In this regard, the guidelines set by the American Association of Equine Practitioners advocate evidence-based strongyle control in horses. It recommends targeted treatment of all heavy egg shedders [> 500 eggs per gram (EPG) of feces] while the low shedders (0-200 EPG) are left untreated to maintain susceptible parasite refugia in a herd. As 50-75% of adult horses in a herd are low shedders, preventing them from unnecessary anthelmintic exposure is critical to tackling resistance. There are various fecal egg count (FEC) techniques with many modifications and variations in use, but none is identified as a gold standard and methods comparison studies are lacking. We hypothesized that the diagnostic performance of commonly used quantitation methodologies differs and the FEC methods must be evaluated to determine the gold standard. In this regard, we performed methods comparison studies using polystyrene beads with size and specific gravity comparable to strongyle eggs, as proxy. The linearity of 12 commonly used FEC methodologies (3 techniques with 4 different solutions) was studied using bead standards in the clinically applicable range (63 to 1,000) to determine their suitability for strongyle egg counts. Deming regression analysis identified Mini-FLOTAC with sugar (specific gravity 1.33) as the test with the greatest coefficient of determination. All tests underestimated the true bead count, and we determined a correction factor (CF) for each test to estimate the true count. CF negates the preference for a gold standard test. Finally, we analyzed the validity of CF for 5 tests with R2>0.95 to accurately quantify strongyle eggs from 40 different horses. Overall, this study identified methodologies with the highest diagnostic performance and the limitations to standardizing routine FEC tests to promote uniformity in implementing AAEP parasite control guidelines.

Preprint ARTICLE | doi:10.20944/preprints202307.1904.v2

The Indirect Effects of Vitamin D3 on the Aging Process According to Gender

Daniela Florina Trifan, Adrian Gheorghe Tirla, Calin Mos, Adrian Danciu, Florian Bodog, Felicia Manole, Timea Claudia Ghitea

Subject: Medicine And Pharmacology, Surgery Keywords: Face-lifting; vitamin D; collagen; sex difference

Online: 31 July 2023 (11:38:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1948.v1

Progress in Language Abilities Related to Reading Comprehension – Domain Specific Intervention on Executive Functioning

Iveta Kovalčíková, Jochanan Veerbeek, Bart Vogelaar, Martin Klimovič, Eva Gogová

Subject: Social Sciences, Language And Linguistics Keywords: reading comprehension; language; executive functioning; domain-specific cognitive stimulation; low-performing pupil; Exefun-READ

Online: 28 July 2023 (08:26:24 CEST)

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Preprint REVIEW | doi:10.20944/preprints202307.1165.v1

Considerations, Advances, and Challenges Associated with the Use of Specific Emitter Identification in the Security of Internet of Things Deployments: A Survey

Joshua H. Tyler, Mohamed K.M. Fadul, Donald R. Reising

Subject: Engineering, Electrical And Electronic Engineering Keywords: Specific Emitter Identification, Radio Frequency Fingerprinting, Physical Layer Authentication, Physical Layer Security, Internet of Things

Online: 18 July 2023 (07:37:34 CEST)

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Initially introduced almost thirty years ago for the express purpose of providing electronic warfare systems the capabilities to detect, characterize, and identify radar emitters, Specific Emitter Identification (SEI) has recently received a lot of attention within the research community as a physical layer technique for securing Internet of Things (IoT) deployments. This attention is due in large part to SEI’s demonstrated success in passively and uniquely identifying wireless emitters using traditional machine learning and the success of Deep Learning (DL) within the natural language processing and computer vision areas. SEI exploits distinct and unintentional features present within an emitter’s transmitted signals. The existence of these distinctive and unintentional features is attributed to slight manufacturing and assembly variations that exist within and between the components, sub-systems, and systems that comprise an emitter’s Radio Frequency (RF) front end. Although sufficient to facilitate SEI, these features do not hinder normal operations such as detection, channel estimation, timing, and demodulation. However, despite the plethora of SEI publications, it has remained largely a focus of academic endeavors that primarily focus on proof-of-concept demonstration and little to no use in operational networks for various reasons. The focus of this survey is a review of SEI publications from the perspective of its use as a practical, effective, and usable IoT security mechanism, thus we use IoT requirements and constraints (e.g., wireless standard, nature of their deployment) as a lens through which each reviewed paper is analyzed. Previous surveys have not taken such an approach and have only used IoT as motivation, a setting, or a context. In this survey, we consider operating conditions, SEI threats, SEI at scale, publicly available data sets, and SEI considerations that are dictated by the fact that it is to be employed by IoT devices or IoT infrastructure.

Preprint REVIEW | doi:10.20944/preprints202307.1094.v1

Do Vaccines Increase or Decrease Susceptibility to Diseases Other Than Those They Protect Against?

Alberto Rubio-Casillas, Elrashdy M. Redwan, Vladimir N. Uversky, Mikolaj Raszek

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: non-specific effects of vaccines; tolerance; immune training; excess deaths; IgG4 antibodies.

Online: 17 July 2023 (09:59:57 CEST)

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Preprint REVIEW | doi:10.20944/preprints202307.0633.v1

Exploring the Therapeutic Potential of Natural Products on Polycystic Ovarian Syndrome (PCOS): A Mini Review of Lipid Profile, Blood Glucose, and Ovarian Histological Improvements

Syawany Wahid, Muhammad Danial Che Ramli, Ezza Fazleen Mohd Fathil, Muhammad Naim Rosli, Mohd Helmy Mokhtar

Subject: Medicine And Pharmacology, Reproductive Medicine Keywords: natural products; polycystic ovarian syndrome; lipid profile; sex hormone; blood glucose

Online: 11 July 2023 (05:19:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0425.v1

Anomalous Ferromagnetic Phase in the Gd1-xErxB4 Series: Crystal Growth, Thermal and Magnetic Properties

Sueli H. Masunaga, V. B. Barbeta, F. Abud, M. S. Torikachvilli, R. F. Jardim

Subject: Physical Sciences, Condensed Matter Physics Keywords: tetraborides; susceptibility; specific heat; geometric magnetic frustration; antiferromagnetism; flux method; Shastry Sutherland

Online: 7 July 2023 (07:40:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0310.v1

Palatal Rugae as a Discriminating Factor in Determining Sex: A Method Applicable in Forensic Odontology?

Andrea Trizzino, Pietro Messina, Fabio M Sciarra, Stefania Zerbo, Antonina Argo, Giuseppe Alessandro Scardina

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: palatal rugae; sex; forensic dentistry

Online: 5 July 2023 (12:38:18 CEST)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202307.0289.v1

Profitability assessment of precision agriculture applications – a step forward in farm management

Christos Karydas, Myrto Chatziantoniou, Ourania Tremma, Alexandros Milios, Kostas Stamkopoulos, Vangelis Vassiliadis, Spiros Mourelatos

Subject: Environmental And Earth Sciences, Other Keywords: precision agriculture; site-specific fertilization; ifarma; PreFer

Online: 5 July 2023 (11:26:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0262.v1

Synthesis, ¹²³I-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with Tributylstannyl Prosthetic Group in Their Structures

Lutfi A. Hasnowo, Maria S. Larkina, Evgenii V. Plotnikov, Vitalina Bodenko, Feruza Yuldasheva, Elena Stasyuk, Stanislav A. Petrov, Nikolai Y. Zyk, Aleksei E. Machulkin, Nikolay I. Vorozhtsov, Elena K. Beloglazkina, Valentine G. Nenajdenko, Vladimir Tolmachev, Anna Orlova, Alexander G. Majouga, Mekhman S. Yusubov

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: DCL ligand; iodine radioisotopes; radiolabeled pharmaceuticals; targeted delivery; prostatic specific membrane antigen; prostate cancer

Online: 5 July 2023 (04:43:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0133.v1

Tumor-Specific Targeting of Polymer Drug Delivery Systems with Recombinant Proteins Bound via Tris(Nitrilotriacetic Acid)

Michal Pechar, Vlastimil Král, Lucie Woldřichová, Ladislav Androvič, Eliška Hrdá, Robert Pola, Sára Pytlíková, Martin Studenovský, Libor Kostka, Vladimír Šubr, Tomáš Etrych, Olga Kočková, Jéssica Mariane Ferreira Mendes, Milan Fábry, Richard Laga

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: Hydrophilic polymers; Thermo-responsive polymers; Polymer drug delivery system; Tumor-specific targeting; Recombinant proteins; Non-covalent attachment; Tris(nitrilotriacetic acid) ligation

Online: 4 July 2023 (08:01:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.2253.v1

Patient-Specific Preictal Pattern-Aware Epileptic Seizure Prediction with Federated Learning

Raghdah Saemaldahr, Mohammad Ilyas

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Epilepsy; Seizure Prediction; Preictal; Federated Learning (FL); Spiking Encoder; Graph Convolutional Neural Network (GCNN); Patient-specific Personalization

Online: 30 June 2023 (14:48:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1817.v1

Sex/gender Differences in the Language Profiles of Italian Children with Autism Spectrum Disorder

Jessica Barsotti, Gloria Mangani, Roberta Nencioli, Antonio Narzisi, Lucia Pfanner, Anna Maria Chilosi, Paola Cipriani, Alice Mancini, Angela Cosenza, Raffaella Tancredi, Sara Calderoni

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Language and communication; sex/gender; Autism Spectrum Disorder; children

Online: 26 June 2023 (13:54:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1435.v1

A-DSCNN: Depthwise Separable Convolutional Neural Network Inference Chip Design using an Approximate Multiplier

Jin-Jia Shang, Nicholas Phipps, I-Chyn Wey, Tee Hui Teo

Subject: Engineering, Electrical And Electronic Engineering Keywords: Application-Specific Integrated Circuits; Approximate Multiplier; CMOS; Convolutional Neural Network; Depthwise Separable Convolution; Processing Element

Online: 21 June 2023 (03:49:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1242.v1

Exploring the Evolutionary Relics of Sex-chromosomes of Divergent Animal Species through Comparative Analysis of the Predicted SSR Sequences and CpG Islands

Barinder Singh Grewal, Shilpa Tewari, Håkon Hægland, Chandra Shekhar Mukhopadhyay

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Microsatellite; CpG island; sex chromosomes; DNA markers

Online: 16 June 2023 (12:41:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0867.v1

Sex Differences In Glomerular Lesions, Atherosclerosis Progression, And In The Response To Angiotensin-Converting Enzyme Inhibitors In The Apoe^-/- Mice Model

Adrián Mallén, Ronny Rodriguez-Urquia, Rafael Alvarez, Eduard Dorca-Duch, Estanis Navarro, Miguel Hueso

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: Sex differences; Chronic Kidney Disease; Atherosclerosis; Foam Cells; Parietal Epithelial Cells (PECs); Angiotensin-Converting Enzyme Inhibitors (ACEi)

Online: 13 June 2023 (03:22:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0843.v1

Sex Differences in Frequencies of B and T Cell Subpopulations of Human Cord Blood

Michelle Bous, Charline Sarah Schmitt, Muriel Charlotte Hans, Regine Weber, Nasenien Nourkami-Tutdibi, Sebastian Tenbruck, Bashar Haj Hamoud, Gudrun Wagenpfeil, Elisabeth Kaiser, Erich-Franz Solomayer, Michael Zemlin, Sybelle Goedicke-Fritz

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: B cells; T cells; B1 cells; human; white blood cells; cord blood; development; ontogeny; sex differences; gender medicine

Online: 12 June 2023 (13:33:46 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0833.v1

The Price of Human Evolution: Cancer-Testis-Antigens, the Decline in Male Fertility and the Increase in Cancer

Jekaterina Erenpreisa, Ninel M Vainshelbaum, Marija Lazovska, Roberts Karklins, Kristine Salmina, Pawel Zayakin, Felikss Rumnieks, Inna Inashkina, Dace Pjanova, Juris Erenpreiss

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Cancer-testis-antigens; parthenogenetic; polyploid giant cancer cells; PGCCs; genome fragility; phylostratigraphic analysis; innate immunity-placentation; endogenous retroviruses; sex determination; male infertility; endocrine disruption; environmental pollution

Online: 12 June 2023 (12:59:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0605.v1

Synthesis and Evaluation of 99mTc-labeled PSMA-targeted Tracers Based on the Lys-urea-Aad Pharmacophore for Detecting Prostate Cancer with Single Photon Emission Computed Tomography

Kelly Lu, Chengcheng Zhang, Zhengxing Zhang, Hsiou-Ting Kuo, Nadine Colpo, François Bénard, Kuo-Shyan Lin

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: prostate-specific membrane antigen (PSMA); technetium-99m; single photon emission computed tomography (SPECT); molecular imaging; HYNIC

Online: 8 June 2023 (08:11:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0587.v1

Development of Clause Complexity in Children with Specific Language Impairment/Language Development Disorder. A Longitudinal Study

Claudia Araya, Carmen Julia Coloma, Camilo Quezada, Paula Benavente

Subject: Social Sciences, Language And Linguistics Keywords: Grammar; clause complexity; longitudinal study; Specific Language Impairment (SLI); Developmental Language Disorder (DLD).

Online: 8 June 2023 (04:41:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0050.v1

Neuron-Specific Enolase (NSE) as a Biomarker for Autistic Spectrum Disease (ASD)

Felician Stancioiu, Raluca Bogdan, Radu Dumitrescu

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: ASD; autism; autistic spectrum disease; NSE; Neuron-specific enolase; autism biomarker; neuroinflammation; neuronal apoptosis; mTOR

Online: 1 June 2023 (07:30:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0011.v1

Update on Desensitization Strategies and Drugs on Hyperimmune Patients for Kidney Transplantation

Maurizio Salvadori

Subject: Medicine And Pharmacology, Transplantation Keywords: Desensitization; Donor specific antibodies; HLA system; antibodies identification; B cells; Plasma cells; Complement; New drugs; Desensitization; Donor specific antibodies; HLA system; B cells; Plasma cells; Complemennt; New drugs

Online: 1 June 2023 (03:17:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.2257.v1

Genetic Diversity and Population Structure of Bursaphelenchus xylophilus in Central China based on SNP Markers

Aixia Yang, Xiaolei Ding, Yuan Feng, Tingting Chen, Jianren Ye

Subject: Biology And Life Sciences, Forestry Keywords: Bursaphelenchus xylophilus; SNP; genetic diversity; population differentiation (List three to ten pertinent keywords specific to the article yet reasonably common within the subject discipline.)

Online: 31 May 2023 (13:23:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1836.v3

The Combination of Binding-Avidity of Ovomucoid-Specific IgE Antibody and Specific IgG4 Antibody Can Predict Positive Outcome of Oral Food Challenge during Stepwise Slow Oral Immunotherapy in Children with Hen’s Egg Allergy

Shoichiro Taniuchi, Rika Sakai, Takashi Nishida, Meguru Goma, Masatoshi Mitomori, Aya Imaide, Masahiro Enomoto, Masamitsu Nishino, Yo Okizuka, Hiroshi Kido

Subject: Biology And Life Sciences, Food Science And Technology Keywords: oral immunotherapy; hen’s egg allergy; IgE binding-avidity; ovomucoid specific IgE; ovomucoid specific IgG4; oral food challenge

Online: 31 May 2023 (02:28:20 CEST)

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Preprint REVIEW | doi:10.20944/preprints202305.1568.v1

Gender: a Postmodern idea Developed in Association with the Modern Concept of Sex; Implications for Evolving Sexuality

Carol Nash

Subject: Social Sciences, Gender And Sexuality Studies Keywords: gender; modern thought; sex; capitalism; standardization; eugenics; postmodern thought; sexuality

Online: 23 May 2023 (04:42:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1451.v1

Management’s Discretionary Assessments of Goodwill Impairments—Evidence from STOXX Europe 600

Frode Kjærland, Kristian Forbord, Are Oust, Håkon Stephani

Subject: Business, Economics And Management, Accounting And Taxation Keywords: goodwill impairment; IFRS; earnings management; company-specific factors; fixed effects

Online: 19 May 2023 (16:49:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1440.v1

Development of an Accurate Polymerase Chain Reaction (PCR) Assay for Genetic Sex Identification in Lumpfish (Cyclopterus lumpus) based on Male-specific anti-Mullerian Hormone (amh) Gene

Kasidis Chaiyasut, Paul Merviel, Peter Palma, Johanna Perschthaler, Eduardo Jimenez Fernandez, Andrew Davie, Alejandro P. Gutierrez

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Anti-Müllerian hormone; Cyclopterus lumpus; Male-specific marker; Genetic sex identification

Online: 19 May 2023 (11:36:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1251.v1

Length of Stay in Emergency Department by ICD-10 Specific and Non-Specific Diagnoses: A Single-Centre Retrospective Study

Bartosz Miazgowski, Cezary Pakulski, Tomasz Miazgowski

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: length of stay; emergency department; ICD-10 classification; non-specific diagnoses

Online: 17 May 2023 (12:59:54 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202305.1119.v1

Adult-Type Granulosa Cell Tumor of the Testis: A Report of a Case and a Discussion of the Literature

Georgios Zervopoulos, Nikolaos Mitsimponas, Filippos Venetsanos, Athanasios Papathanasis

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: Testis; granulosa-cell tumor; adult–type; sex cord-stromal tumor of testis; testicular cancer

Online: 16 May 2023 (07:27:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0978.v1

Long-Chain Acyl Coenzyme a Dehydrogenase, a Key Player in Metabolic Rewiring/Invasiveness in Experimental Tumors and Human Mesothelioma Cell Lines

Daniel L. Pouliquen, Giacomo Ortone, Letizia Rumiano, Alice Boissard, Cécile Henry, Stéphanie Blandin, Catherine Guette, Chiara Riganti, Joanna Kopecka

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: malignant mesothelioma; metabolism; mitochondria; long-chain specific acyl-CoA dehydrogenase; fatty acid β-oxidation, biomarker

Online: 15 May 2023 (05:27:55 CEST)

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Preprint REVIEW | doi:10.20944/preprints202305.0677.v1

Gender Differences in Oxidative Stress in Relation to Cancer Susceptibility and Survival

Alessandro Allegra, Santino Caserta, Sara Genovese, Giovanni Pioggia, Sebastiano Gangemi

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: gender differences; cancer; oxidative stress; oestrogens; testosterone; antioxidant; reactive oxygen species; sex hormones; mitochondria.

Online: 10 May 2023 (03:44:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0353.v1

Impact of COVID-19 on Quality of Life in Long-term Advanced Rectal Cancer Survivors

Daniel Anton Blasko, Claudia Schweizer, Tim Fitz, Christoph Schröter, Christopher Sörgel, Annett Kallies, Rainer Fietkau, Luitpold Valentin Distel

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: quality of life; COVID-19; pandemic; rectal cancer; radiochemotherapy; age; sex; stage

Online: 5 May 2023 (10:39:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0112.v1

Tracing the Influence of Manure as a Complex Mixture on the Soil Sorption of Pharmaceuticals Back to Selected Chemical Constituents

Sören Thiele-Bruhn, Wei Zhang

Subject: Environmental And Earth Sciences, Soil Science Keywords: Atenolol; caffeine; sulfadiazine; dissolved organic matter; sewage; specific sorption; sorption competition

Online: 3 May 2023 (07:55:31 CEST)

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Preprint REVIEW | doi:10.20944/preprints202305.0031.v1

Mast Cells as a Potential Target of Molecular Hydrogen in Regulating the Local Tissue Microenvironment

Dmitri Atiakshin, Andrey Kostin, Artem Volodkin, Anna Nazarova, Viktoriya Shishkina, Dmitry Esaulenko, Igor Buchwalow, Markus Tiemann, Mami Noda

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: molecular hydrogen; reactive oxygen intermediates; mast cells; secretome; specific mast cell proteases; local tissue microenvironment; inflammation

Online: 1 May 2023 (11:54:37 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202305.0013.v1

Renal Mast Cell Specific Proteases in the Pathogenesis of Tubulointerstitial Fibrosis: Case Report

Dmitri Atiakshin, Sergey Morozov, Vladimir Dlin, Andrey Kostin, Michael Ignatyuk, Galina Kuzovleva, Sergey Baiko, Igor Buchwalow, Markus Tiemann

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: mast cells; tryptase; carboxypeptidase A3; chymase; fibrogenic niche; kidney fibrosis; specific tissue microenvironment

Online: 1 May 2023 (04:12:22 CEST)

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Kidney fibrosis is a complex polyetiological progressive disease manifesting as an intraorgan proliferation of the connective tissue with the appearance of cicatricial changes. However, pathogenetic mechanisms of renal fibrosis remain poorly understood. The paper highlights features of the protease phenotype and histotopography of mast cells (MCs) found in the kidney, as the key players in extracellular matrix remodeling in nephrofibrosis, detected in a patient diagnosed with "nephrosclerosis with the non-functioning upper pole of the duplex right kidney in the junction of refluxing megaureter of the upper pole of the duplex right kidney". The highest content of MCs was found in the kidney areas with fibrotic changes. MCs were actively involved in the development of inflammatory and fibrotic changes in limited loci of the specific tissue microenvironment of the kidney through targeted secretion of tryptase, chymase, and carboxypeptidase A3 to the vascular endothelium, nephron epithelium, interstitium cells, and components of the intercellular substance. The formation of a profibrotic environment in the kidney interstitium was facilitated by epigenetic effects of tryptase promoting epithelial-mesenchymal transition (EMT) of the nephron epithelium. A selectively increased number and targeted secretory activity of MCs in limited loci of the kidney parenchyma without visible pathological changes evidence a trigger pathogenetic role of specific proteases in the formation of a local microenvironment with a profibrogenic metabolic profile. Thus, MCs are actively involved in the mechanisms of formation and evolution of fibrogenic niches in the kidney; this fact can be used to develop new strategies for therapeutic options of tubulointerstitial fibrosis resulted from chronic kidney injury. Further study of the molecular phenotype of mast cells reveals new fundamental mechanisms of fibrosis pathogenesis being a significant tool for personalized therapy in nephrology.

Preprint ARTICLE | doi:10.20944/preprints202304.1276.v1

Understanding Transcription Factors and How They Affect Metabolic Processes in Cucumber Sex Determination

Szymon Turek, Aparna Aparna, Agnieszka Skarzyńska, Wojciech Pląder, Magdalena Pawełkowicz

Subject: Biology And Life Sciences, Plant Sciences Keywords: transcription factors; interactome network; sex development; sex determination; Cucumber (Cucumis sativus); metabolomic processes

Online: 1 May 2023 (00:01:26 CEST)

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Preprint REVIEW | doi:10.20944/preprints202304.1102.v1

Sex Specificities of Human Placental Adaptive Changes: The Influence of Maternal Obesity

Esther Dos Santos, Marta Hita Hernandez, Valérie Sérazin, François Vialard, Marie-Noëlle Dieudonné

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: Maternal obesity; placenta; environmental adaptation; sex specificities; reproduction

Online: 28 April 2023 (04:06:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints202304.0989.v1

An Emerging Animal Model for Querying the Role of Whole Genome Duplication in Development, Evolution, and Disease

Mara Schvarzstein, Fatema Alam, Muhammad Toure, Judith L Yanowitz

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Whole genome duplication; tetraploidy; polyploidy; aneuploidy; Caenorhabditis; WGD model (List three to ten pertinent keywords specific to the article yet reasonably common within the subject discipline.)

Online: 26 April 2023 (12:43:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0818.v1

Micromagnetic Approach to the Metastability of a Magnetite Nanoparticle and Specific Loss Power As Function of the Easy-Axis Orientation

Nathaly Roa, Johans Restrepo

Subject: Physical Sciences, Other Keywords: dynamic phase transition; alternating magnetic field; magnetic nanoparticle; hyperthermia; specific loss power

Online: 24 April 2023 (04:16:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0457.v1

Lateral Flow Biosensor for microRNA Detection Based on Peptide Nucleic Acid Probes

Aodi Liu, Qingjie Xia, Yang Huang, Haoheng Liu, Jin Tian, Kezhou Li

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Peptide nucleic acid; microRNA detection; duplex specific nuclease; Early diagnosis of pancreatic cancer; Lateral flow biosensor

Online: 18 April 2023 (02:48:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0023.v1

PSI-mediated Vacuolar Sorting is not Disrupted in Arabidopsis leb-2 Mutant

Tatiana Cardoso, Miguel Sampaio, João Neves, Sofia Oliveira, Inês Moura, Ana Séneca, José Pissarra, Susana Pereira, Cláudia Pereira

Subject: Biology And Life Sciences, Plant Sciences Keywords: Arabidopsis; ER-bodies; aspartic proteinases; Plant Specific Insert; Vacuolar sorting; Endomembranes

Online: 3 April 2023 (10:36:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202001.0350.v2

An Alternative Model of Gravitational Forces in Nature Using the Combined Effects of Repulsion and Attraction Forces on Gaseous Molecules

Chithra Piyadasa

Subject: Physical Sciences, Atomic And Molecular Physics Keywords: gravitational attraction; gravitational repulsion; intermolecular forces; thermal energy; specific heat; inverse cube law

Online: 21 March 2023 (15:44:21 CET)

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Preprint REVIEW | doi:10.20944/preprints202303.0371.v1

Nuclei on the Rise: When Nuclei-Based Methods Meet Next-Generation Sequencing

Tamer Butto, Kanak Mungikar, Peter Baumann, Jennifer Winter, Beat Lutz, Susanne Gerber

Subject: Medicine And Pharmacology, Hematology Keywords: Nuclei isolation; Next-generation sequencing; Cell-type specific isolation; Epigenetics; Transcriptomics; Single cell sequencing; Single nucleus sequencing

Online: 21 March 2023 (06:40:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202303.0165.v1

Modelling Time–Dependent Flow through Railway Ballast

Raed Alrdadi, Michael H. Meylan

Subject: Engineering, Civil Engineering Keywords: free surface; steady state; unsteady state; railway ballast; fouling ratio; specific yield; finite element method

Online: 9 March 2023 (03:31:03 CET)

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Preprint ARTICLE | doi:10.20944/preprints202303.0049.v1

Dietary and Sexual Correlates of Gut Microbiota in the Japa-Nese Gecko, Gekko japonicus (Schlegel, 1836)

Xin-Ru Jiang, Ying-Yu Dai, Yu-Rong Wang, Kun Guo, Yu Du, Jian-Fang Gao, Long-Hui Lin, Peng Li, Hong Li, Xiang Ji, Yan-Fu Qu

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: ASVs; diet habit; Gekko japonicus; gut microbiota; sex

Online: 3 March 2023 (01:31:32 CET)

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Preprint REVIEW | doi:10.20944/preprints202302.0516.v1

The Confound of Hemodynamic Response Function Variability in Resting-State Functional MRI Studies

D Rangaprakash, Robert Barry, Gopikrishna Deshpande

Subject: Biology And Life Sciences, Biophysics Keywords: BOLD fMRI; HRF; resting state connectivity; aging; sex differences; confound

Online: 28 February 2023 (09:32:04 CET)

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Preprint REVIEW | doi:10.20944/preprints202302.0305.v1

National and Ethnic Mutation Frequency Databases: Cross Comparison and Future Direction

Shumaila Khan, Mehmood Alam, Shahnaz Khan, Wahab Khan, Ihsan Rabbi, Iqbal Qasim

Subject: Computer Science And Mathematics, Information Systems Keywords: genetic databases; mutation disorders; ethnic specific databases

Online: 17 February 2023 (07:59:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints201909.0247.v3

Four‑stage Evolution of Diabetes or Whole‑body Insulin Resistance (WBIR) Driven by Sequential Progression of Tissue‑specific Glycation‑induced Insulin Resistance (GIIR)

Song Jae LEE, Sang Won Shin

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: obesity; obesity paradox; diabetes; insulin resistance (IR); whole body insulin resistance (WBIR); tissue specific insulin resistance; muscle insulin resistance (MIR); subcutaneous insulin resistance (s AIR); visceral adipose insulin resistance (v AIR); hepatic insulin resistance (HIR); lipid induced insulin resistance (LIIIR); glycation induced insulin resistance (GIIIR); metabolic syndrome

Online: 14 February 2023 (09:38:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202301.0403.v1

Are Men Better at Recognizing Emojis than Facial Expressions?

Linda Dalle Nogare, Alice Cerri, Alice Mado Proverbio

Subject: Social Sciences, Cognitive Science Keywords: visual perception; emotion; emoji; emoticon; sex differences; anger; fear; emotional communication; texting

Online: 23 January 2023 (08:43:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0290.v3

New Workflow Predicts Drug Targets Against SARS-CoV-2 via Metabolic Changes in Infected Cells

Nantia Leonidou, Alina Renz, Reihaneh Mostolizadeh, Andreas Dräger

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: host-virus interactions; tissue-specific model; COVID-19; SARS-CoV-2; antiviral targets; flux balance analysis; flux variability analysis; reaction knockout; host-derived enforcement; metabolic modeling; virus mutations; software engineering; Python

Online: 17 January 2023 (01:50:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202301.0273.v1

Identifying Patients in Whom the Follow-up Scheme after Robot-assisted Radical Prostatectomy Could be Optimized in the First Year after Surgery: Reducing Healthcare Burden

Hans Veerman, Sophia Van der Graaf, Dennie Meijer, Marinus Jan Hagens, Corinne N. Tillier, Pim J. Van Leeuwen, Henk G. Van der Poel, André N. Vis

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: prostatic neoplasms; prostatectomy; prostate-specific antigen; follow-up; aftercare; recurrence; delivery of healthcare

Online: 16 January 2023 (07:38:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0420.v1

Normative scores for CrossFit® Open Workouts: 2011 - 2022

Gerald T. Mangine, Nina Grundlingh, Yuri Feito

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: fitness assessment; sport-specific; athlete classification; high-intensity functional training; sex differences

Online: 22 December 2022 (06:34:53 CET)

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Preprint BRIEF REPORT | doi:10.20944/preprints202212.0219.v1

SARS-CoV-2 Breakthrough Infections after Third Doses Boost IgG Specific Salivary and Blood Antibodies

Maria Noel Badano, Matias Pereson, Florencia Sabbione, Irene Keitelman, Natalia Aloisi, Roberto Chuit, Maria Marta Elizalde de Bracco, Susana Fink, Patricia Bare

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: SARS-CoV-2 breakthrough infections; vaccines; anti-spike antibody levels; humoral response; IgG specific salivary antibodies

Online: 13 December 2022 (02:28:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0211.v1

Klotho Regulated by Estrogen Plays a Key Role in Sex Differences in Stress Resilience

Zhinei Tan, Yongxia Li, Yinzheng Guan, Javed Iqbal, Chenyue Wang, Xinming Ma

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: klotho; estrogen; hippocampus; chronic stress; sex difference; stress resilience

Online: 13 December 2022 (01:09:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0185.v1

De Novo Assembly and Annotation of 11 Diverse Shrub Willow (Salix) Genomes Reveals Novel Gene Organization in Sex-Linked Regions

Brennan Hyden, Kai Feng, Timothy B Yates, Sara Jawdy, Chelsea Cereghino, Lawrence B Smart, Wellington Muchero

Subject: Biology And Life Sciences, Plant Sciences Keywords: Salix; shrub willow; genome assembly; sex determination

Online: 12 December 2022 (01:46:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0152.v1

Eugenio Martelli, Matilde Zamboni, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe Massimo Sangiorgi, Mariangela Valentina Puci, Allegra Rosa Martelli, Teresa Messina, Paolo Frigatti, Maria Pia Borrelli, Carlo Ruotolo, Ilaria Ficarelli, Paolo Rubino, Francesco Pezzo, Luciano Carbonari, Andrea Angelini, Edoardo Galeazzi, Luca Calia Di Pinto, Franco Michelino Fiore, Armado Palmieri, Giorgio Ventoruzzo, Giulia Mazzitelli, Franco Ragni, Antonio Bozzani, Enzo Forliti, Claudio Castagno, Pietro Volpe, Mafalda Massara, Diego Moniaci, Elisa Pagliasso, Tania Peretti, Mauro Ferrari, Nicola Troisi, Pietro Modugno, Maurizio Maiorano, Umberto Marcello Bracale, Marco Panagrosso, Mario Monaco, Giovanni Giordano, Giuseppe Natalicchio, Antonella Biello, Giovanni Maria Celoria, Alessio Amico, Mauro Di Bartolo, Massimiliano Martelli, Roberta Munaó, Davide Razzano, Giovanni Colacchio, Francesco Bussetti, Gaetano Lanza, Antonio Cardini, Bartolomeo Di Benedetto, Mario De Laurentis, Maurizio Taurino, Pasqualino Sirignano, Pierluigi Cappiello, Andrea Esposito, Santi Trimarchi, Silvia Romagnoli, Andrea Padricelli, Giorgio Giudice, Adolfo Crinisio, Giovanni Di Nardo, Giuseppe Battaglia, Rosario Tringale, Salvatore De Vivo, Rita Compagna, Valerio Stefano Tolva, Ilenia D'Alessio, Ruggiero Curci, Simona Giovannetti, Giuseppe D'Arrigo, Giusi Basile, Dalmazio Frigerio, Gian Franco Veraldi, Luca Mezzetto, Arnaldo Ippoliti, Fabio Massimo Oddi, Alberto Maria Settembrini

Subject: Medicine And Pharmacology, Hematology Keywords: chronic limb-threatening ischemia; outcome; sex; age; limb salvage

Online: 8 December 2022 (09:39:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202211.0355.v1

Risk Assessment of Transgender People: Development of Rodent Models Mimicking Gender-Affirming Hormone Therapies and Identification of Sex-Dimorphic Liver Genes as Novel Biomarkers of Sex Transition

Roberta Tassinari, Alessia Tammaro, Gabriele Lori, Sabrina Tait, Andrea Martinelli, Luigia Cangemi, Paolo Frassanito, Francesca Maranghi

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: testosterone; estrogen; cyprotenone acetate; masculinizing; feminizing; cytochrome P450; sex-specific genes

Online: 18 November 2022 (10:10:00 CET)

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Preprint BRIEF REPORT | doi:10.20944/preprints202211.0215.v1

Alterations in Kidney Structures Caused by Age Vary According to Sex and Dehydration Condition

Susana Quirós Cognuck, Lucas Ferreira de Almeida, Wagner L. Reis, Márcia S. Silva, Gislaine Almeida Pereira, Sandra V. Zorro, André S. Mecawi, Terezila Machado Coimbra, Lucila L.K. Elias, José Antunes Antunes Rodrigues

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: aging; body composition; kidney; sex differences

Online: 11 November 2022 (03:53:06 CET)

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Preprint REVIEW | doi:10.20944/preprints202211.0075.v1

Use of Antiandrogens as Therapeutic Agents in COVID-19 Patients

Efstathios S. Giotis, Emine Cil, Greg N. Brooke

Subject: Biology And Life Sciences, Virology Keywords: coronavirus; TMPRSS2; ACE2; SARS-CoV-2; androgens; sex hormones; antiandrogens

Online: 3 November 2022 (09:21:09 CET)

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Preprint REVIEW | doi:10.20944/preprints202209.0487.v2

Innate Immunity in Cardiovascular Diseases – Identification of Novel Molecular Players and Targets

Wolfgang Poller, Bettina Heidecker, Enrico Ammirati, Andreas W Kuss, Ana Tzvetkova, Wolfram C Poller, Carsten Skurk, Arash Haghikia

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Immunology; innate immunity; immunogenetics; noncoding genome; tRNA biology; evolutionary genetics (list 3-10 specific to the article yet reasonably common within the subject discipline)

Online: 1 November 2022 (09:55:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202209.0377.v1

Calibrating A Comprehensive Immune Age Metric to Analyze the Cross Sectional Age-Related Decline in Cardiorespiratory Fitness

Peter Bröde, Maren Claus, Patrick D. Gajewski, Stephan Getzmann, Klaus Golka, Jan G. Hengstler, Edmund Wascher, Carsten Watzl

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: aging; immunosenescence; physical fitness; physical activity; obesity; sex

Online: 26 September 2022 (05:00:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202209.0361.v1

Impact of Sex in Left Atrial Indices for Prognosis of Heart Failure with Preserved Ejection Fraction

Shiro Hoshida, Koichi Tachibana, Nobutaka Masunaga, Yukinori Shinoda, Tomoko Minamisaka, Hirooki Inui, Keisuke Ueno, Masahiro Seo, Masamichi Yano, Takaharu Hayashi, Akito Nakagawa, Yusuke Nakagawa, Shunsuke Tamaki, Takahisa Yamada, Yoshio Yasumura, Yohei Sotomi, Shungo Hikoso, Daisaku Nakatani, Yasushi Sakata

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Ed/Ea; Fine-Gray model; HFpEF; LAVI; sex

Online: 23 September 2022 (08:09:57 CEST)

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Preprint REVIEW | doi:10.20944/preprints202208.0220.v1

Promoting Oncolytic Vector Replication With Switches That Detect Ubiquitous Mutations

Michael Renteln

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Molecular switches; oncolytic vectors; patient-specific ubiquitous mutations; targeted therapy; multi-region sequencing; molecular biology

Online: 11 August 2022 (11:50:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0178.v1

A Genome-Wide Association Study Reveals New Genes in a Molecular Network Associated With Alcohol Dependence and Related Clinical Measures

Anastasia Levchenko, Sergey Malov, Alexey Antonik, Anastasia Protsvetkina, Kseniya V. Rybakova, Alexander Kanapin, Alexey N. Yakovlev, Anna Y. Nenasteva, Anton E. Nikolishin, Nikolay Cherkasov, Natalia A. Chuprova, Anna S. Blagonravova, Angelica V. Sergeeva, Tatyana V. Zhilyaeva, Maria K. Denisenko, Raul R. Gainetdinov, Alexander O. Kibitov, And Evgeny M. Krupitsky

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: alcohol dependence; comorbidity; gene network; genome-wide association study; sex differences

Online: 9 August 2022 (10:35:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0426.v1

Predicting the Cross-Coordinated Immune Response Dynamics in Sars-Cov-2 Infection: Implications for Disease Pathogenesis

Dmitry Grebennikov, Antonina Karsonova, Marina Loginova, Valentina Casella, Andreas Meyerhans, Gennady Bocharov

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: SARS-CoV-2 infection; innate immune response; antigen-specific immune response; kinetic coordination; mathematical model; pathogenesis, long COVID-19

Online: 27 July 2022 (15:11:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0372.v1

Cell Compartment-specific Folding of Ty1 Long Terminal Repeat Retrotransposon RNA Genome

Małgorzata Zawadzka, Angelika Andrzejewska-Romanowska, Julita Gumna, David J. Garfinkel, Katarzyna Pachulska-Wieczorek

Subject: Biology And Life Sciences, Virology Keywords: RNA genome; RNA structure; Cell compartment-specific folding; LTR-retrotransposon; gRNA dimerization; gRNA cyclization; tRNA annealing; Ty1; Gag.

Online: 25 July 2022 (10:07:00 CEST)

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Preprint REVIEW | doi:10.20944/preprints202207.0281.v1

Software-Defined Networks for Optical Networks using Flexible Orchestration : Advances, Challenges and Opportunities

Kenneth Nsafoa-Yeboah, Eric Tchao, Bright Yeboah-Akowuah, Benjamin Kommey, Andrew Selasi Agbemenu, Eliel Keelson, Mohammad Monirujjaman Khan

Subject: Computer Science And Mathematics, Computer Networks And Communications Keywords: Optical networks; software-defined networks; fifth-generation wireless network(5G); network service orchestrators; customer- specific requirements; Quality of service, flexibility.

Online: 19 July 2022 (07:44:11 CEST)

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Preprint REVIEW | doi:10.20944/preprints202207.0125.v1

A Fish of Multiple Faces, which Show us Enigmatic and Incredible Phenomena in Nature: Biology and Cytogenetics of the Genus Carassius

Martin Knytl, Adrian Forsythe, Lukáš Kalous

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: hybridization; sexuality; asexuality; biotype; species; sex determination; ploidy level; Carassius auratus complex

Online: 7 July 2022 (09:56:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0401.v1

Assessing Loss of Regulatory Divergence, Genome–Transcriptome Incongruence, and Preferential Expression Switching in Abaca/ Banana Backcrosses

Nelzo C. Ereful, Antonio G. Lalusin, Antonio C. Laurena

Subject: Biology And Life Sciences, Plant Sciences Keywords: abaca (Musa textilis); allelic imbalance; regulatory divergence; banana (M. balbisiana); allele-specific expression

Online: 29 June 2022 (09:34:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0234.v1

Alcohol Dependence Induces CRF Sensitivity in Female Central Amygdala GABA Synapses

Larry Rodriguez, Dean Kirson, Sarah A. Wolfe, Reesha R. Patel, Florence P. Varodayan, Angela E. Snyder, Pauravi J. Gandhi, Sophia Khom, Roman Vlkolinksy, Michal Bajo, Marisa Roberto

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: corticotropin releasing factor (CRF); patch-clamp electrophysiology; sex difference; alcohol use disorder (AUD); Gamma-Aminobutyric Acid (GABA); central amygdala (CeA); spontaneous inhibitory post synaptic currents (sIPSCs)

Online: 16 June 2022 (08:41:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints202206.0121.v1

Factors Modulating COVID-19: A Mechanistic Understanding Based on the Adverse Outcome Pathway Framework

Laure-Alix Clerbaux, Maria Cristina Albertini, Núria Amigó, Anna Beronius, Gillina F.G. Bezemer, Sandra Coecke, Evangelos P. Daskalopoulos, Giusy Del Giudice, Dario Greco, Lucia Grenga, Alberto Mantovani, Amalia Muñoz, Elma Omeragic, Nikolaos Parissis, Mauro Petrillo, Laura A. Saarimäki, Helena Soares, Kristie Sullivan, Brigitte Landesmann

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: SARS-CoV-2 infection; COVID-19; modulating factors; Adverse Outcome Pathway; sex; age; co-morbidities; lifestyle; environment; pre-existing conditions

Online: 8 June 2022 (09:47:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0108.v1

Neuropsychological Findings in Adults with Triple X Syndrome

Maarten Otter, Bea Campforts, Connie TRM Stumpel, Thérèse Van Amelsvoort, Claudia Vingerhoets, Marjan Drukker

Subject: Social Sciences, Cognitive Science Keywords: Triple X syndrome; Adults; Neurocognitive functioning; Sex Chromosomal Disorders; Attention; Psychomotor speed; Executive functioning

Online: 7 June 2022 (11:26:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0409.v1

Are There Sex Differences in Self-Reported Childhood Maltreatment in Major Depressive and Bipolar Disorders? A Retrospective Cross-Sectional Study

Daniela Caldirola, Tatiana Torti, Francesco Cuniberti, Silvia Daccò, Alessandra Alciati, Koen Schruers, Giovanni Martinotti, Domenico De Berardis, Giampaolo Perna

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: childhood trauma; major depressive disorder; bipolar disorder; sex difference; age

Online: 31 May 2022 (03:39:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0295.v1

Sex Differences in Nutritional Status and Associated Risk Factors Among Cardiovascular Disease (Cvd) Patients in Lahore, Pakistan; A Cross-Sectional Descriptive Study

Amina Faheem, Qaisar Raza, Sanaullah Iqbal, Rakhshanda Batool, Umer Faheem

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: Cardiovascular Diseases; Sex differences; Pakistani; Dietary intake patterns

Online: 23 May 2022 (10:30:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0286.v1

Classical-Relativistic Variability of Inertia of Photon Displacement Mass in the Matter and the Specific Vacuum Temperature

Daniel Souza Cardoso, José Rafael Bordin

Subject: Physical Sciences, Optics And Photonics Keywords: photon inertia; inertia momenta; photon inertia variability; photon inertia momenta variability; specific vacuum temperature; Abraham momenta; Minkowski momenta; relativistic energy wave; translational inertia; rotational inertia; photon displacement mass

Online: 21 March 2022 (11:21:56 CET)

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Preprint REVIEW | doi:10.20944/preprints202112.0380.v2

Considerations and Challenges for Sex-Aware Drug Repurposing

Jennifer Fisher, Emma Jones, Victoria Flanary, Avery Williams, Elizabeth Ramsey, Brittany Lasseigne

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: sex differences; drug repurposing; sex-bias; sex-aware; review; therapeutics; pharmaceuticals; computational drug repurposing

Online: 8 March 2022 (10:34:42 CET)

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Sex differences are essential factors in disease etiology and manifestation in many diseases such as cardiovascular disease, cancer, and neurodegeneration (1). The biological influence of sex differences (including genomic, epigenetic, hormonal, immunological, and metabolic differences between males and females) and the lack of biomedical studies considering sex differences in their study design has led to several policies. For example, the National Institute of Health’s (NIH) sex as a biological variable (SABV) and Sex and Gender Equity in Research (SAGER)) policies to motivate researchers to consider sex differences (2). However, drug repurposing, a promising alternative to traditional drug discovery by identifying novel uses for FDA-approved drugs, lacks sex-aware methods that can improve the identification of drugs that have sex-specific responses (1,3–5). Sex-aware drug repurposing methods either select drug candidates that are more efficacious in one sex or deprioritize drug candidates based on if they are predicted to cause a sex-bias adverse event (SBAE), unintended therapeutic effects that are more likely to occur in one sex. Computational drug repurposing methods are encouraging approaches to develop for sex-aware drug repurposing because they can prioritize sex-specific drug candidates or SBAEs at lower cost and time than traditional drug discovery. Sex-aware methods currently exist for clinical, genomic, and transcriptomic information (3,6,7). They have not expanded to other data types, such as DNA variation, which has been beneficial in other drug repurposing methods that do not consider sex (8). Additionally, some sex-aware methods suffer from poorer performance because a disproportionate number of male and female samples are available to train computational methods (3). However, there is development potential for several different categories (i.e., data mining, ligand binding predictions, molecular associations, and networks). Low-dimensional representations of molecular association and network approaches are also especially promising candidates for future sex-aware drug repurposing methodologies because they reduce the multiple hypothesis testing burden and capture sex-specific variation better than the other methods (9,10). Here we review how sex influences drug response, the current state of drug repurposing including with respect to sex-bias drug response, and how model organism study design choices influence drug repurposing validation.

Preprint ARTICLE | doi:10.20944/preprints202202.0310.v1

Translating the Biology of Rodents’ Sex-Recognition and Mate-Recognition to Humans’: Bridging the Pheromonal-Visual Gap

Yehuda Salu

Subject: Social Sciences, Behavior Sciences Keywords: Sex-recognition; mate-recognition; sexual orientation; puberty; vomeronasal-organ; VNO; learning sexual behavior; Medial-geniculate-nucleus; MGN; MASH

Online: 24 February 2022 (10:06:07 CET)

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