ARTICLE
|
doi:10.20944/preprints202310.1628.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
acute myeloid leukemia; mass spectrometry; proteomic; phosphoproteomic; relapse; mitochondria; FAB subtypes
Online: 25 October 2023 (10:07:27 CEST)
REVIEW
|
doi:10.20944/preprints202310.0962.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
oxygen; nanobubbles; hypoxia; mitochondria; metabolism, molecular; drug delivery; cancer, stress; innovation
Online: 16 October 2023 (11:09:22 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1993.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
mitochondria; membrane; fusion; Mifofusin; amphipathic helix; divalent cations; lipid packing defects
Online: 28 July 2023 (11:29:25 CEST)
REVIEW
|
doi:10.20944/preprints202306.1903.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Fasting; autophagy; long-COVID; post-vaccination syndrome; spike protein; mitochondria; mitophagy
Online: 27 June 2023 (12:33:46 CEST)
REVIEW
|
doi:10.20944/preprints202306.1306.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Fasting; autophagy; long-COVID; post-vaccination syndrome; spike protein; mitochondria; mitophagy
Online: 19 June 2023 (07:39:57 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0287.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
HAX1; Che-1/AATF; apoptosis; mitochondria; oxidative stress; breast cancer; ERα
Online: 17 February 2023 (01:50:45 CET)
REVIEW
|
doi:10.20944/preprints202301.0538.v2
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
placenta; mitochondria; preeclampsia; disease subclasses; pregnancy; hypertension; reactive oxygen species; therapies
Online: 10 February 2023 (04:09:05 CET)
REVIEW
|
doi:10.20944/preprints202206.0421.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Mitochondria; Respiratory chain; Krebs cycle; Succinate; Cancer; Encephalopathy; SDH, SDHI; pesticides
Online: 30 June 2022 (08:31:22 CEST)
REVIEW
|
doi:10.20944/preprints202109.0109.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
proteomics; transcriptomics; DNA methylation; mitochondria; metabolism; OXPHOS; ASD; neurogenesis; gliosis; neurodevelopment
Online: 6 September 2021 (17:14:37 CEST)
REVIEW
|
doi:10.20944/preprints202011.0227.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Organelle transport; Charcot-Marie-Tooth; Axonal transport deficiency; Neurodegeneration; Cytoskeleton; Mitochondria
Online: 6 November 2020 (08:55:15 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Diabetic Cardiomyopathy; Hyperglycemia; Ischemia/Reperfusion Injury; Metabolism; Mitochondria; Remote Conditioning; Exercise
Online: 17 March 2020 (08:52:25 CET)
ARTICLE
|
doi:10.20944/preprints201909.0043.v3
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Myalgic Encephalomyelitis; Chronic Fatigue Syndrome; mitochondria; Complex V; TORC1; Seahorse respirometry
Online: 3 February 2020 (09:34:29 CET)
ARTICLE
|
doi:10.20944/preprints201905.0094.v1
Subject:
Physical Sciences,
Thermodynamics
Keywords:
time; availability; irreversibility; time dilation; biological clock; metabolic efficiency; telomere; mitochondria
Online: 8 May 2019 (11:21:50 CEST)
ARTICLE
|
doi:10.20944/preprints201903.0271.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
glucocorticoid receptor; 11HSD; mitochondria; NFκB; inflammation; ovary; uterus; polycystic ovary syndrome
Online: 28 March 2019 (14:05:40 CET)
ARTICLE
|
doi:10.20944/preprints201801.0280.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
cold stress; heat stress; stress recovery; mitochondria; proteomics; respiration; Brassica; angiosperms
Online: 30 January 2018 (10:31:07 CET)
REVIEW
|
doi:10.20944/preprints201701.0039.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
apoptosis; autophagy; cancer; crosstalk; curcumin; endoplasmic reticulum; hormatic behavior; lysosomes; mitochondria
Online: 10 January 2017 (03:46:51 CET)
REVIEW
|
doi:10.20944/preprints202401.0426.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
PDAC; molecular alterations; oncogenic pathways; targeted therapy; preclinical; clinical; combinational therapy; clinical trials
Online: 5 January 2024 (06:28:11 CET)
ARTICLE
|
doi:10.20944/preprints202312.0054.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Ex Vivo Resistance Platform; CAF-mediated Resistance; Combinations of cytotoxic and targeted drugs
Online: 1 December 2023 (07:57:41 CET)
REVIEW
|
doi:10.20944/preprints202307.0552.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer chemotherapy; transmembrane receptors; EGFR; targeted protein degradation; furfuryl-quinolin-triazole-thiol chemicals
Online: 10 July 2023 (07:23:13 CEST)
ARTICLE
|
doi:10.20944/preprints202307.0161.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Non-small cell lung cancer; Targeted Gene Therapy; Immune Checkpoint Inhibitors; Machine Learning
Online: 4 July 2023 (07:57:03 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0400.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
transcriptionally targeted oncolytic adenovirus; gynecologic cancer; human samples; cytokines; ovarian cancer; tumor stroma
Online: 6 May 2023 (09:25:49 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0343.v1
Subject:
Medicinal Chemistry,
Chemistry And Materials Science
Keywords:
targeted alpha therapy; alpha-emitter; thorium-226; uranium-230; isotope generator; extraction chromatography
Online: 20 February 2023 (14:17:58 CET)
REVIEW
|
doi:10.20944/preprints202210.0362.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
gut microbiome; time-restricted feeding; intermittent fasting; targeted approach; hormonal signaling; metabolic regulators
Online: 24 October 2022 (12:00:48 CEST)
REVIEW
|
doi:10.20944/preprints202206.0160.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; HER2-positive; estrogen receptor positive; triple-positive; HER2-targeted therapy; immunotherapy
Online: 10 June 2022 (11:03:05 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0257.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
metastatic melanoma; targeted therapy; immune checkpoint inhibitor therapy; survival; statutory health insurance data
Online: 15 November 2021 (11:50:07 CET)
ARTICLE
|
doi:10.20944/preprints202109.0289.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
BRD9; Prostate Cancer; SWI/SNF; Survival; pathways; signal transduction; human cohorts; targeted therapy
Online: 16 September 2021 (13:51:57 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0424.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
4-Phenylbutyric acid; Colon-targeted drug delivery; Colitis; Prodrug; ER stress; Chemical chaperone
Online: 19 July 2020 (19:15:20 CEST)
REVIEW
|
doi:10.20944/preprints202403.0790.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
plant; mitochondria; RNA helicase; RNA binding protein; post-transcription; RNA metabolism; splicing
Online: 14 March 2024 (07:42:46 CET)
ARTICLE
|
doi:10.20944/preprints202402.0373.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
oxidative stress; Twendee M®; antioxidant; chronic fatigue syndrome; ROS; mitochondria; inflammation
Online: 6 February 2024 (11:06:29 CET)
ARTICLE
|
doi:10.20944/preprints202309.0190.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Mitochondria; Neural Progenitor Cells; Optic nerve compression; Optic nerve crush; Vps35; Syntaxin12
Online: 5 September 2023 (04:55:42 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1248.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
mitochondria; simulated microgravity; cellular spheroids; TCam-2 cells; oxidative stress; antioxidant barrier
Online: 18 July 2023 (13:49:21 CEST)
REVIEW
|
doi:10.20944/preprints202306.1724.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
canine mammary tumors; metabolism, cancer; mitochondria; metabolic reprogramming; glucose; amino acids; lipids
Online: 25 June 2023 (08:00:35 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1603.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Tafazzin; Barth Syndrome; Single-Nucleus RNA-sequencing; Cardiomyopathy; Mitochondria; Gene Expression; Metabolism
Online: 22 June 2023 (11:31:02 CEST)
REVIEW
|
doi:10.20944/preprints202305.1930.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
low-frequency magnetic fields; ion parametric resonance; calcium; cryptochrome; mitochondria; biochemical oscillations
Online: 26 May 2023 (11:27:48 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1698.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Cancer; Aggressiveness; Mitochondria; Acadvl; Fatty acid beta oxidation; Biomarker; Proteomics; Malignant mesothelioma
Online: 24 May 2023 (05:06:41 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0351.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
astrocytes; hypoglycemia; diabetes mellitus, type 1; mitochondria; glycemic control; hypothalamus; glutamic acid.
Online: 18 August 2022 (14:24:35 CEST)
ARTICLE
|
doi:10.20944/preprints202207.0316.v1
Subject:
Social Sciences,
Cognitive Science
Keywords:
acute injury; antioxidant; behavior; mitochondria; mitoquinone; neuroinflammation; oxidative stress; repeated mild TBI
Online: 21 July 2022 (08:17:28 CEST)
ARTICLE
|
doi:10.20944/preprints202201.0113.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Group II; Intron; Splicing; PPR; Respiration; Complex I; Mitochondria; Embryogenesis; Arabidopsis; Angiosperms.
Online: 10 January 2022 (12:46:06 CET)
REVIEW
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
mitochondria; mitochondrial DNA; nervous tissue, OxPhos complexes; bioenergetics; genomics; proteomics; mitochondrial diseases
Online: 17 June 2021 (15:12:01 CEST)
REVIEW
|
doi:10.20944/preprints202103.0401.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
insulin; insulin receptor; brain insulin resistance; mitochondria; brain; neuron; H2O2; glutamate excitotoxicity.
Online: 15 March 2021 (17:38:24 CET)
REVIEW
|
doi:10.20944/preprints202103.0372.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
insulin; insulin receptor; brain insulin resistance; mitochondria; brain; neuron; H2O2; glutamate excitotoxicity.
Online: 15 March 2021 (11:46:08 CET)
REVIEW
|
doi:10.20944/preprints202102.0163.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
ATP; OXPHOS; ATP synthase; mitochondria; biochemical assays; fluorescence microscopy; genetically-encoded biosensors
Online: 5 February 2021 (14:45:04 CET)
REVIEW
|
doi:10.20944/preprints202010.0512.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Mitochondria; Ubiquitin; Proteasome; mitophagy; autophagy; proteolysis; protein import; Protein Quality Control; Metabolism
Online: 26 October 2020 (10:49:39 CET)
ARTICLE
|
doi:10.20944/preprints202310.1260.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Protons; X-rays; oral squamous cell carcinoma; extracellular vesicles; non-targeted effects of radiation
Online: 19 October 2023 (09:59:48 CEST)
ARTICLE
|
doi:10.20944/preprints202307.0262.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
DCL ligand; iodine radioisotopes; radiolabeled pharmaceuticals; targeted delivery; prostatic specific membrane antigen; prostate cancer
Online: 5 July 2023 (04:43:46 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0315.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Type I nitroreductase; NfsB; Crystal structure; Prodrug; Metronidazole; Targeted cellular ablation; Tinidazole; CB1954; Dinitrotoluene
Online: 17 March 2023 (03:22:59 CET)
ARTICLE
|
doi:10.20944/preprints202212.0214.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Breast; Targeted Radiotherapy; Lung injury; Heart injuries; Health-Related Quality Of Life; Irradiation toxicity.
Online: 13 December 2022 (01:17:52 CET)
COMMUNICATION
|
doi:10.20944/preprints202112.0420.v3
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Non-targeted methods; method validation; food fraud; food authenticity; mass spectrometry; spectroscopy; NGS; NMR
Online: 23 May 2022 (11:10:00 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0724.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
TNBC; dasatinib; poly(styrene-co-maleic acid) micelles; nanoformulation; metabolism; EPR; nanomedicine; targeted therapy.
Online: 27 April 2021 (13:56:12 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
HBOC; statewide random sampling; cancer survivorship; targeted intervention; tailored intervention; black participants; family recruitment
Online: 5 September 2019 (16:16:34 CEST)
REVIEW
|
doi:10.20944/preprints201902.0245.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cyclin-dependent kinases; cyclin-dependent kinase 4 and 6 inhibitors; targeted therapies; breast cancer
Online: 27 February 2019 (04:48:54 CET)
ARTICLE
|
doi:10.20944/preprints201609.0024.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
neurofibromatosis type 1; congenital pseudarthrosis of the tibia; whole-exome sequencing; targeted sequencing; BCOR
Online: 7 September 2016 (11:19:00 CEST)
ARTICLE
|
doi:10.20944/preprints202309.2064.v1
Subject:
Computer Science And Mathematics,
Security Systems
Keywords:
adversarial attacks; artificial intelligence; machine learning; defense mechanisms; system integrity; model vulnerabilities; advanced attack techniques; Fast Gradient Sign Method (FGSM); Carlini and Wagner Attack (C&W); targeted attacks; non-targeted attacks; blackbox attacks
Online: 29 September 2023 (08:42:10 CEST)
REVIEW
|
doi:10.20944/preprints202402.1176.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Ca2+ signaling; Ca2+ regulation; miltefosine; acidocalcisome; mitochondria; Ca2+ Channel; sphingosine; Chagas Disease; Leishmaniasis
Online: 21 February 2024 (04:22:08 CET)
REVIEW
|
doi:10.20944/preprints202310.2087.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
aging; chronodisruption; clock genes; Bmal1; inflammaging; oxidative stress; mitochondria; skeletal muscle; sarcopenia; melatonin
Online: 1 November 2023 (03:02:46 CET)
ARTICLE
|
doi:10.20944/preprints202310.1076.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Hepatocellular carcinoma (HCC); Human immunodeficiency virus (HIV); hepatitis; inflammatory cytokines; mitochondria DNA deletion
Online: 17 October 2023 (11:46:43 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0977.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
human pathogen; aspergillus; mitochondria; single nucleotide polymorphism; clonal expansion; recombination; copy number variation
Online: 15 September 2023 (05:32:30 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0215.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Homocysteine; endothelial cell; angiogenesis; zebrafish; ER stress; actin cytoskeleton; mitochondria; glycolysis; TCA cycle
Online: 5 September 2023 (05:24:08 CEST)
ARTICLE
|
doi:10.20944/preprints202307.2112.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
Alzheimer's disease; oxidative stress; Twendee X®︎; antioxidant; dementia; mitochondria; reactive oxygen species
Online: 1 August 2023 (02:49:59 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0302.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Mitochondria; Eclipsed protein targeting; Yeast model system; TDH1; TDH2; Dual protein tar-geting
Online: 5 May 2023 (04:57:13 CEST)
REVIEW
|
doi:10.20944/preprints202207.0130.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
Keywords: mitochondria; stress resilience; plasticity; stress; kynurenine; Alzheimer’s disease; neurodegenerative; depression; anxiety; psychiatric
Online: 8 July 2022 (03:56:36 CEST)
ARTICLE
|
doi:10.20944/preprints202102.0545.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
trastuzumab, HER2, extracellular vesicles, breast cancer, proteomic analysis, immunoelectron microscopy, TOP1, CD63, mitochondria.
Online: 24 February 2021 (11:38:41 CET)
REVIEW
|
doi:10.20944/preprints202101.0120.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
mTOR; ATP; protein synthesis; autophagy; amino acids; nutrition; adipose tissue; muscle; sarcopenia; mitochondria
Online: 6 January 2021 (14:32:22 CET)
HYPOTHESIS
|
doi:10.20944/preprints202004.0269.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
COVID-19; SARS-CoV-2; pandemic; antibiotics; immune response; mitochondria; epidemiology; health policy
Online: 16 April 2020 (12:14:30 CEST)
REVIEW
|
doi:10.20944/preprints201810.0023.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Unfolded protein response; ER morphology; Mitochondria-associated ER membrane; ER-PM contact sites
Online: 2 October 2018 (13:41:17 CEST)
REVIEW
|
doi:10.20944/preprints201809.0521.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Unfolded protein response; ER morphology; Mitochondria-associated ER membrane; ER-PM contact sites
Online: 26 September 2018 (15:44:54 CEST)
REVIEW
|
doi:10.20944/preprints202403.1011.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
retinoblastoma; RB1; E2F; Targeted Therapy; Therapeutic Vulnerabilities; Spliceosome; Cell Cycle; Epigenetic Regulators; Ubiquitin-Proteasome Pathway
Online: 18 March 2024 (10:29:38 CET)
ARTICLE
|
doi:10.20944/preprints202401.0334.v1
Subject:
Public Health And Healthcare,
Other
Keywords:
recurrent ovarian cancer; platinum-sensitive relapse; platinum-resistant relapse; platinum refractory relapse; targeted therapy; chemotherapy
Online: 4 January 2024 (04:18:09 CET)
CASE REPORT
|
doi:10.20944/preprints202306.1950.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
inflammatory breast carcinoma; targeted biological therapy; HER2 overexpression; multidisciplinary treatment; aggressive cancer management; systemic chemotherapy
Online: 28 June 2023 (07:12:56 CEST)
REVIEW
|
doi:10.20944/preprints202210.0450.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Tumor microenvironment; stromal cells; immune cells; ECM; cancer hallmarks; hypoxia; exosomes; drug resistance; targeted therapy
Online: 28 October 2022 (09:57:34 CEST)
REVIEW
|
doi:10.20944/preprints202208.0220.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Molecular switches; oncolytic vectors; patient-specific ubiquitous mutations; targeted therapy; multi-region sequencing; molecular biology
Online: 11 August 2022 (11:50:12 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0137.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Taihe silky fowl; metabolic components; un-targeted metabolome; breed and feed; biosynthesis of amino acids
Online: 15 April 2022 (05:47:06 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0300.v1
Subject:
Computer Science And Mathematics,
Applied Mathematics
Keywords:
CAR T; Targeted Radionuclide Therapy; TRT; Mathematical Model; Multiple Myeloma; Immunotherapy; Daratumumab; CS1; Combination Therapy
Online: 17 September 2021 (09:32:33 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0638.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
pancreatic ductal adenocarcinoma; targeted therapies; therapeutic resistance; tumor microenvironment; desmoplasia; collagen; collagenase; attenuated Salmonella typhimurium
Online: 28 June 2021 (10:36:31 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0692.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
RACK1; HIV-1; IRES; Hepatitis C; HCV; AZT; HTA; Host-targeted antiviral; HEK293T; SD29-14
Online: 26 April 2021 (20:35:00 CEST)
COMMENTARY
|
doi:10.3390/sci2030070
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
small molecule inhibitor; personalized medicine; precision medicine; oncology; targeted therapy; drug delivery; drug screening; chemotherapy
Online: 8 September 2020 (00:00:00 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0349.v1
Subject:
Aging,
Biology And Life Sciences
Keywords:
aging; neuroinflammation; cognitive impairment; Tusc2; Fus1; mitochondria; calcium; brain immune populations; sex-dependent changes
Online: 7 May 2024 (08:17:45 CEST)
REVIEW
|
doi:10.20944/preprints202404.0628.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Plant-based diet; lifestyle; in-stent restenosis; stent thrombosis; ISR; ST; atherosclerosis; mitochondria; telomere
Online: 9 April 2024 (08:49:59 CEST)
REVIEW
|
doi:10.20944/preprints202401.0245.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Parkinson’s disease; substantia nigra; dopamine; neuromelanin; α-synuclein; oxidative stress; mitochondria; calcium; energy; ATP
Online: 3 January 2024 (10:41:13 CET)
ARTICLE
|
doi:10.20944/preprints202305.1517.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
Antiviral; Thiourea derivatives; Hepatitis B Virus; Chronic hepatitis B infection; Mitochondria dysfunction; Exhausted hepatocytes
Online: 29 May 2023 (14:29:16 CEST)
REVIEW
|
doi:10.20944/preprints202305.0677.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
gender differences; cancer; oxidative stress; oestrogens; testosterone; antioxidant; reactive oxygen species; sex hormones; mitochondria.
Online: 10 May 2023 (03:44:32 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0125.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
ATP synthase; cancer cell; mitochondria; glioblastoma; integrin αvβ3; NADH dehydro-genase; tetrac; thyroid hormones
Online: 9 March 2022 (01:55:26 CET)
REVIEW
|
doi:10.20944/preprints202312.2256.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
acute myeloid leukemia; TP53 mutations; TP53-mutated acute myeloid leukemia; novel targeted AML therapies; AML immunotherapies
Online: 29 December 2023 (05:27:17 CET)
REVIEW
|
doi:10.20944/preprints202311.0094.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Casein Kinase II; Musculoskeletal; Osteoarthritis; Osteoporosis; CX-4945; CIBG-300; Cell Signaling; Drug Development; Targeted therapy
Online: 1 November 2023 (13:18:42 CET)
REVIEW
|
doi:10.20944/preprints201811.0143.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
clear cell renal cell carcinoma; tumor evolution; tumor ecology; intratumor heterogeneity; multisite tumor sampling; targeted therapy
Online: 6 November 2018 (13:30:54 CET)
ARTICLE
|
doi:10.20944/preprints201804.0307.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
gastric cancer; ramucirumab; paclitaxel; second line therapy; vascular endothelial growth factor receptor 2; targeted therapy; nutrition
Online: 24 April 2018 (06:01:56 CEST)
REVIEW
|
doi:10.20944/preprints202312.0932.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
oxidative phosphorylation; cancer; mitochondria; metabolic shift; type 2 diabetes; insulin resistance; therapy; nutritional adjuvants; glutaminolysis
Online: 13 December 2023 (03:26:13 CET)
REVIEW
|
doi:10.20944/preprints202311.1813.v1
Subject:
Public Health And Healthcare,
Public, Environmental And Occupational Health
Keywords:
bilirubin; cadmium; diabetes type 2; glucose homeostasis; gluconeogenesis; glycolysis; heme; heme oxygenase; hyperglycemia; mitochondria; obesity.
Online: 30 November 2023 (02:04:00 CET)
ARTICLE
|
doi:10.20944/preprints202311.0337.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
modular nanotransporters; Keap1; intracellular delivery; CETSA; FLIM-FRET; FLIM; thermophoresis; chlorine e6; targeting to mitochondria
Online: 7 November 2023 (02:49:52 CET)
REVIEW
|
doi:10.20944/preprints202307.1807.v2
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
polycystic ovary syndrome (PCOS); ovary; uterus; placenta; mitochondria; biogenesis; mtDNA; metabolism; mitochondrial dynamics; oxidative stress
Online: 21 August 2023 (10:16:55 CEST)
REVIEW
|
doi:10.20944/preprints202307.0484.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
Cyclophilin D (CyPD); mitochondrial permeability transition (mPTP); Alzheimer’s Disease (AD); Parkinson’s Disease (PD); mitochondria; neurodegeneration
Online: 7 July 2023 (11:06:01 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0978.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
malignant mesothelioma; metabolism; mitochondria; long-chain specific acyl-CoA dehydrogenase; fatty acid β-oxidation, biomarker
Online: 15 May 2023 (05:27:55 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202304.0796.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
Sepsis Treatment; Mitochondria; Adenosine Triphosphate (ATP); Pyruvate dehydrogenase complex and thiamine; Glycolysis; Glucose and insulin.
Online: 23 April 2023 (08:39:15 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0511.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
glaucoma; optic neuropathy; mitochondria; optic nerve crush; confocal scanning ophthalmoscope; distribution; Thy1-mito-YFP mice
Online: 28 January 2023 (03:05:08 CET)
ARTICLE
|
doi:10.20944/preprints202107.0212.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
TDP-43; Jun; REST; ERK; mitochondria; cell stress; aggregation; transcription factors; transgenic mice; subcellular fractionation
Online: 9 July 2021 (10:14:47 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0360.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Riboflavin transporter deficiency; motor neurons; mitochondria; energy metabolism; electron microscopy; antioxidants; SOD2; oxidative stress; neurodegeneration
Online: 12 November 2020 (18:14:17 CET)
ARTICLE
|
doi:10.20944/preprints202002.0029.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Myalgic Encephalomyelitis; Chronic Fatigue Syndrome; mitochondria; Complex V; TORC1; Seahorse respirometry; biomarker; diagnosis; ME/CFS
Online: 3 February 2020 (10:36:05 CET)
ARTICLE
|
doi:10.20944/preprints202312.1002.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
intranasal spray; drug delivery; respiratory transport modeling; respiratory diseases; upper airway physiology; targeted nasal therapy; gentlemistTM technology
Online: 13 December 2023 (13:05:13 CET)
ARTICLE
|
doi:10.20944/preprints202105.0546.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
triple negative breast cancer; Pembrolizumab; Atezolizumab; chemotherapy; anti-PD-L1; biomarkers; targeted therapies; development of novel drugs
Online: 24 May 2021 (09:23:50 CEST)
REVIEW
|
doi:10.20944/preprints202001.0030.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
histone deacetylase 6 inhibitor; personalized treatment; heat shock protein 90α; leukemia stem cells; imatinib resistance; targeted therapy
Online: 4 January 2020 (06:18:22 CET)