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Preprint ARTICLE | doi:10.20944/preprints202007.0599.v1

Crisis Self-Efficacy and Work Commitment of Education Workers among Public Schools during COVID-19 Pandemic

Erick Baloran, Jenny Hernan

Subject: Social Sciences, Education Keywords: crisis self-efficacy; work commitment; education workers; public schools; COVID-19 pandemic

Online: 24 July 2020 (14:47:56 CEST)

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Working Paper REVIEW

An Overview of Imaging Lidar Sensors for Autonomous Vehicles

Santiago Royo, Maria Ballesta

Subject: Engineering, Automotive Engineering Keywords: lidar, ladar, time of flight, 3D imaging, point cloud, MEMS, scanners, photodetectors, lasers, autonomous vehicles, self-driving car

Online: 8 August 2019 (12:23:48 CEST)

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Preprint REVIEW | doi:10.20944/preprints202003.0001.v2

Coronavirus Disease 2019 – COVID-19

Kuldeep Dhama, Khan Sharun, Ruchi Tiwari, Shubhankar Sircar, Sudipta Bhat, Yashpal Singh Malik, Karam Pal Singh, Wanpen Chaicumpa, D. Katterine Bonilla-Aldana, Alfonso J. Rodriguez-Morales

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: emerging coronavirus; 2019-nCoV; SARS-CoV-2; COVID-19; diagnosis; vaccines; therapy; one health

Online: 13 April 2020 (02:29:00 CEST)

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Working Paper ARTICLE

Detection of Coronavirus Disease (COVID-19) Based on Deep Features and Support Vector Machine

Prabira Kumar Sethy, Santi Kumari Behera, Pradyumna Kumar Ratha, Preesat Biswas

Subject: Engineering, Electrical And Electronic Engineering Keywords: coronavirus; COVID-19; diagnosis; deep features; SVM

Online: 22 April 2020 (05:58:22 CEST)

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The detection of coronavirus (COVID-19) is now a critical task for the medical practitioner. The coronavirus spread so quickly between people and approaches 100,000 people worldwide. In this consequence, it is very much essential to identify the infected people so that prevention of spread can be taken. In this paper, the deep feature plus support vector machine (SVM) based methodology is suggested for detection of coronavirus infected patient using X-ray images. For classification, SVM is used instead of deep learning based classifier, as the later one need a large dataset for training and validation. The deep features from the fully connected layer of CNN model are extracted and fed to SVM for classification purpose. The SVM classifies the corona affected X-ray images from others. The methodology consists of three categories of Xray images, i.e., COVID-19, pneumonia and normal. The method is beneficial for the medical practitioner to classify among the COVID-19 patient, pneumonia patient and healthy people. SVM is evaluated for detection of COVID-19 using the deep features of different 13 number of CNN models. The SVM produced the best results using the deep feature of ResNet50. The classification model, i.e. ResNet50 plus SVM achieved accuracy, sensitivity, FPR and F1 score of 95.33%,95.33%,2.33% and 95.34% respectively for detection of COVID-19 (ignoring SARS, MERS and ARDS). Again, the highest accuracy achieved by ResNet50 plus SVM is 98.66%. The result is based on the Xray images available in the repository of GitHub and Kaggle. As the data set is in hundreds, the classification based on SVM is more robust compared to the transfer learning approach. Also, a comparison analysis of other traditional classification method is carried out. The traditional methods are local binary patterns (LBP) plus SVM, histogram of oriented gradients (HOG) plus SVM and Gray Level Co-occurrence Matrix (GLCM) plus SVM. In traditional image classification method, LBP plus SVM achieved 93.4% of accuracy.

Preprint REVIEW | doi:10.20944/preprints202012.0452.v1

An Update on Self-Amplifying mRNA Vaccine Development

Anna Blakney, Andrew Geall, Shell Ip

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: RNA; self-amplifying RNA; replicon; vaccine; drug delivery

Online: 18 December 2020 (11:12:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints201903.0128.v1

An Updated Review on the Epidemiology, Pathophysiology, Etiology and Diagnosis of Liver Cirrhosis

Gee Young Geong, Sun Hyung Kang, Chang Min Lee

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: Liver cirrhosis; epidemiology; etiology; risk factors; pathophysiology; diagnosis.

Online: 11 March 2019 (09:44:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints202008.0709.v1

COVID-19 Suicide among Adolescents and Youths during the Lockdown: An Exploratory Study based on Media Reports

Md. Dilshad Manzar, Abdulrhman Albougami, Norina Usman, Mohammed A. Mamun

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: COVID-19; lockdown; psychological impacts; self-harm; suicide; COVID-19 suicide; teenage suicide; adolescent suicide; youth suicide; press reporting suicide

Online: 31 August 2020 (05:43:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201710.0169.v1

A Longitudinal Approach to Biological Psychiatric Research: The PsyCourse Study

Monika Budde, Heike Anderson-Schmidt, Katrin Gade, Daniela Reich-Erkelenz, Kristina Adorjan, Janos L. Kalman, Fanny Senner, Sergi Papiol, Till F. M. Andlauer, Ashley L. Comes, Eva C. Schulte, Farah Klöhn-Saghatolislam , Anna Gryaznova, Maria Hake, Kim Bartholdi, Laura Flatau, Markus Reitt, Silke Quast, Sophia Stegmaier, Milena Meyers, Barbara Emons, Ida Sybille Haußleiter, Georg Juckel, Vanessa Nieratschker, Udo Dannlowski, Max Schmauß, Jörg Zimmermann, Jens Reimer, Sybille Schulz, Jens Wiltfang, Eva Reininghaus, Ion-George Anghelescu, Volker Arolt, Bernhard T. Baune, Carsten Konrad, Andreas Thiel, Andreas J. Fallgatter, Christian Figge, Martin von Hagen, Manfred Koller, Fabian U. Lang, Moritz E. Wigand, Thomas Becker, Markus Jäger, Detlef E. Dietrich, Sebastian Stierl, Harald Scherk, Carsten Spitzer, Here Folkerts, Stephanie H. Witt, Franziska Degenhardt, Andreas J. Forstner, Marcella Rietschel, Markus M. Nöthen, Peter Falkai, Thomas G. Schulze, Urs Heilbronner

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: Schizophrenia; bipolar; psychosis; depression; polygenic risk score; diagnosis; RDoC

Online: 27 October 2017 (11:58:11 CEST)

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Preprint REVIEW | doi:10.20944/preprints202003.0343.v1

Emerging Coronavirus Disease (COVID-19), a Pandemic Public Health Emergency with Animal Linkages: Current Status Update

Yashpal Singh Malik, Shubhankar Sircar, Sudipta Bhat, Obli Rajendran Vinodhkumar, Ruchi Tiwari, Ranjit Sah, Ali A. Rabaan, Alfonso J. Rodriguez-Morales, Kuldeep Dhama

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: coronavirus; 2019-nCoV; SARS-CoV-2; animal coronaviruses; COVID-19; bat coronavirus; zoonoses; epidemiology; transmission; diagnosis; antivirals; prevention and control

Online: 23 March 2020 (07:19:35 CET)

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After the appearance of first cases of ‘pneumonia of unknown origin’ in the Wuhan city, China, during late 2019, the disease progressed fast. Its cause was identified as a novel coronavirus, named provisionally 2019-nCoV. Subsequently, an official name was given as SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) by the International Committee on Taxonomy of Viruses (ICTV) study group. The World Health Organization (WHO) named the Coronavirus disease-2019 as COVID-19. The epidemics of COVID-2019 have been recorded over 113 countries/territories/areas apart from China and filched more than 4292 humans, affecting severely around 1,18,326 cases in a short span. The status of COVID-2019 emergency revised by the WHO within 42 days from Public Health International Emergency (January 30, 2020) to a pandemic (March 11, 2020). Nonetheless, the case fatality rate (CFR) of the current epidemic is on the rise (between 2-4%), relatively is lower than the previous SARS-CoV (2002/2003) and MERS-CoV (2012) outbreaks. Even though investigations are on its way, the researchers across the globe have assumptions of animal-origin of current SARS-CoV-2. A recent case report provides evidence of mild COVID-2019 infection in a pet dog that acquired COVID-2019 infection from his owner in Hong Kong. The news on travellers associated spread across the globe have also put many countries on alert with the cancellation of tourist visa to all affected countries and postponement of events where international visits were required. A few diagnostic approaches, including quantitative and differential real-time polymerase chain reaction assays, have been recommended for the screening of the individuals at risk. In the absence of any selective vaccine against SARS-CoV-2, re-purposed drugs are advocated in many studies. This article discourse the current worldwide situation of COVID-2019 with information on virus, epidemiology, host, the role of animals, effective diagnosis, therapeutics, preventive and control approaches making people aware on the disease outcomes.

Preprint REVIEW | doi:10.20944/preprints202102.0459.v1

Sensor and Sensor Fusion Technology in Autonomous Vehicles: A Review

De Jong Yeong, Gustavo Velasco-Hernandez, John Barry, Joseph Walsh

Subject: Engineering, Automotive Engineering Keywords: autonomous vehicles; self-driving cars; perception; camera; lidar; radar; sensor fusion; calibration; obstacle detection

Online: 22 February 2021 (11:31:02 CET)

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Preprint REVIEW | doi:10.20944/preprints201612.0027.v1

Robots to the Rescue: A Review of Studies on Differential Medical Diagnosis Employing Ontology-Based Chat Bot Technology

Bosede Iyiade Edwards, Idris Oladele Muniru, Adrian David Cheok

Subject: Medicine And Pharmacology, Other Keywords: chatbot technology; ontology-based systems; expert systems; diagnosis; conversational agents; robotics; human-robot interaction; physician-patient relationship; intelligent agents

Online: 6 December 2016 (04:46:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints201607.0070.v1

The Self-Action Leadership Model: A Qualitative, Nomological Expansion of Self-Leadership Theory Rooted in Action Research Theory

Jordan Jensen, Christopher Neck, Rodney Beaulieu

Subject: Social Sciences, Behavior Sciences Keywords: Self-Action Leadership (SAL), SAL model, SAL theory, nomological, existential growth, organizational (or corporate) citizen, SAR project, SAL project, step-habit, Self-Declaration of Independence, Self-Constitution

Online: 23 July 2016 (10:26:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0132.v1

A New Deep Learning Model for Fault Diagnosis with Good Anti-Noise and Domain Adaptation Ability on Raw Vibration Signal

Wei Zhang, Gaoliang Peng, Chuanhao Li, Yuanhang Chen, Zhujun Zhang

Subject: Engineering, Mechanical Engineering Keywords: intelligent fault diagnosis; convolutional neural networks; domain adaptation; anti-noise

Online: 30 January 2017 (12:15:03 CET)

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Preprint REVIEW | doi:10.20944/preprints202004.0155.v1

COVID-19 Testing: Challenges, Limitations and Suggestions for Improvement

Emily Hu

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: COVID-19; Coronavirus; False-negative; Nucleic Acid Test; Screening; Diagnostic Accuracy; Missed Diagnosis; Epidemic; Infectious Disease

Online: 9 April 2020 (14:37:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201712.0020.v1

Suicide, Jews and Judaism

Kate Miriam Loewenthal

Subject: Social Sciences, Law Keywords: suicide; Jewish law; suicide ideation; self-harm

Online: 4 December 2017 (08:27:41 CET)

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Working Paper CONCEPT PAPER

EUROPEAN ME NETWORK (EUROMENE) Expert Consensus on the Diagnosis, Service Provision and Care of People with ME/CFS in Europe

Luis Nacul, Fraçois Jérôme Authier, Carmen Scheibenbogen, Lorenzo Lorusso, Ingrid Helland, Jose Alegre Martin, Carmen Adella Sirbu, Anne Marit Mengshoel, Olli Polo, Uta Behrends, Henrik Nielsen, Patricia Grabowski, Slobodan Sekulic, Nuno Sepulveda., Fernando Esteves Lopez, Pawel Zalewski, Derek Pheby, Jesus Castro-Marrero, Giorgos K Sakkas, Jonas Bergquist, Enrica Capelli, Ivan Brandslund, John Cullinan, Angelika Krumina, Modra Murovska, Ruud Vermuelen, Eliana Lacerda

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome; diagnosis; Health services; clinical care

Online: 16 October 2020 (08:58:18 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202003.0184.v2

Serological Test is an Efficient Supplement for Detecting RNA to Confirm SARS-CoV-2 Infection

Ning-Shao Xia, Gui-Qiang Wang, Wen-Feng Gong

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; diagnosis; antibody; serology; screening

Online: 6 April 2020 (14:09:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202004.0201.v1

Detecting the COVID-19

Pravin Pokhrel, Changpeng Hu, Hanbin Mao

Subject: Biology And Life Sciences, Virology Keywords: diagnosis; detection kits; RT-PCR; immunoassay; false negative; false positive; sensitivity; point-of-care (POC)

Online: 12 April 2020 (16:50:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0062.v1

An Adaptive Self-powered Piezoelectric Energy Harvesting Circuit and Its Application on Bridge Condition Monitoring

Teng Li, Yunxin Zhang, Xinlai Geng

Subject: Engineering, Electrical And Electronic Engineering Keywords: piezoelectric cantilever energy harvester 1; autonomous 2; adaptive 3; self-powered 4; voltage doubler interface circuit 5; closed loop control 6; feed-forward 7; multi-shot technology 8

Online: 12 January 2017 (10:45:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints201609.0049.v1

The Effect of 4-Octyldecyloxybenzoic Acid on Liquid-Crystalline Polyurethane Composites with Triple-Shape Memory and Self-Healing Properties

Jianfeng Ban, Linjiang Zhu, Shaojun Chen, Yiping Wang

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: shape memory; liquid crystalline; self-healing

Online: 15 September 2016 (11:07:50 CEST)

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Preprint REVIEW | doi:10.20944/preprints201705.0104.v1

A Systematic Review: Family Support Integrated To Diabetes Self-Management among Glycemic Uncontrolled Type II DM Patients

Rian Adi Pamungkas, Kanittha Chamroonsawasdi, Paranee Vatanasomcoon

Subject: Social Sciences, Behavior Sciences Keywords: diabetes self-management; family support; glycemic uncontrolled; type 2 DM; systematic review

Online: 12 May 2017 (05:27:28 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints201608.0228.v1

Sweat Gland Biopsy: A Possible Early Diagnostic Tool in the Anderson-Fabry Disease

Giuseppe Pistone, Valentina Caputo, Davide Fattore, Giovanna Tilotta, Maria Rita Bongiorno

Subject: Medicine And Pharmacology, Dermatology Keywords: lysosomal diseases; diagnosis

Online: 30 August 2016 (04:27:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201903.0080.v1

Definition of Internet of Things (IoT) Cyber Risk – Discussion on a Transformation Roadmap for Standardisation of Regulations, Risk Maturity, Strategy Design and Impact Assessment

Petar Radanliev, David De Roure, Jason R.C. Nurse, Pete Burnap, Eirini Anthi, Uchenna Ani, La’Treall Maddox, Omar Santos, Rafael Mantilla Montalvo

Subject: Engineering, Control And Systems Engineering Keywords: Internet of Things; Micro Mart model; Goal-Oriented Approach; transformation roadmap; Cyber risk regulations; empirical analysis; cyber risk self-assessment; cyber risk target state

Online: 6 March 2019 (11:47:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints201711.0037.v1

Social Learning, Self-Efficacy, and Subjective Norm in Exploring Betel Nut Chewing in Taxi Drivers in Taiwan

Tsui-Yun Yang, Hung-Ru Lin

Subject: Social Sciences, Behavior Sciences Keywords: social learning; self-efficacy; subjective norm; betel nut chewing; taxi driver

Online: 6 November 2017 (07:27:59 CET)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202304.0108.v1

Towards a Biological Definition of Parkinson’s Disease

Günter U. Höglinger, Charles H. Adler, Daniela Berg, Christine Klein, Tiago F. Outeiro, Werner Poewe, Ronald Postuma, Jon Stoessl, Anthony E. Lang

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Parkinson’s disease; genetics; α-synuclein; neurodegeneration; clinical manifestation; diagnosis

Online: 7 April 2023 (03:54:11 CEST)

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With the growing hope that disease-modifying treatments could target the molecular basis of neurodegenerative diseases even before the onset of symptoms, there is mounting pressure to define disease entities based on pathophysiology rather than on clinical syndromes. The Alzheimer’s disease research community has recently transitioned from diagnostic criteria based on an amnestic syndrome to a purely biomarker-based disease definition, relying on the demonstration of amyloid-beta pathology, tau pathology, and neurodegeneration. In contrast, current diagnostic criteria for Parkinson’s disease still rely on the presence of the well-described clinical syndrome of parkinsonism, with the addition of characteristic motor- and non-motor signs and symptoms. However, there is now unequivocal evidence that Parkinson’s disease starts years before the onset of parkinsonism. Furthermore, neuropathologically defined Lewy body disease is clinically heterogeneous, combining a range of motor, non-motor, dopaminergic and non-dopaminergic features. Finally, clinically defined Parkinson’s disease has diverse underlying etiologies most, but not all, associated with α-synuclein positive Lewy pathology. In light of recent scientific advances, we propose a biologically based definition for the diagnosis of Parkinson's disease, initially to be used for research purposes. The criteria use a three-component ‘G-S-N’ system. The first is documentation of defined gene variants (‘G’), which cause or strongly predispose to PD as the most upstream component. The second is α-synuclein pathology (‘S’), currently defined as pathological α-synuclein deposition in tissue or positive α-synuclein seeding assays. The third is evidence of underlying neurodegeneration (‘N’), currently defined by specific neuroimaging procedures. The associated clinical syndrome (‘C’) is defined by a single high-specificity feature or multiple lower-specificity features. Initiating this transition will enable the field to fuel both basic and clinical research and move closer to the precision medicine required to develop clinically meaningful disease-modifying therapies. We acknowledge current limitations, ethical implications, and the need for prospective validation of this approach.

Preprint ARTICLE | doi:10.20944/preprints201701.0008.v1

Fabrication of Mechanically Stable Superhydrophobic Aluminium Surface with Excellent Self-Cleaning and Anti-Fogging Properties

Priya Varshney, Soumya Mohapatra, Aditya Kumar

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: Superhydrophobic; Water-repellent; Chemical etching; Self-cleaning; Anti-fogging

Online: 2 January 2017 (17:27:05 CET)

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Preprint REVIEW | doi:10.20944/preprints201710.0117.v1

Trends in Computer-Aided Diagnosis Using Deep Learning Techniques: A Review of Recent Studies on Algorithm Development

Bosede Iyiade Edwards, Nosiba Hisham Osman Khougali, Adrian David Cheok

Subject: Computer Science And Mathematics, Data Structures, Algorithms And Complexity Keywords: computer-aided diagnosis; CAD algorithms; deep neural networks; medical diagnosis; review

Online: 17 October 2017 (11:57:17 CEST)

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Preprint REVIEW | doi:10.20944/preprints202004.0469.v1

Pandemic Coronavirus Disease (COVID-19): Challenges and A Global Perspective

Yashpal Singh Malik, Naveen Kumar, Shubhankar Sircar, Rahul Kaushik, Sudipta Bhatt, Kuldeep Dhama, Parakriti Gupta, Kapil Goyal, Mini P. Singh, Ujjala Ghoshal, Mohamed Ezzat Mahmoud El Zowalaty, O.R. Vinodh Kumar, Mohd. Iqbal Yatoo, Ruchi Tiwari, Mamta Pathak, Shailesh Kumar Patel, Ranjit Sah, Alfonso J. Rodriguez-Morales, Balasubramanian Ganesh, Prashant Kumar, Raj Kumar Singh

Subject: Biology And Life Sciences, Virology Keywords: severe acute respiratory syndrome coronavirus-2; COVID-2019; epidemiology; pathobiology; clinical profile; phyloanalysis; artificial intelligence; diagnosis; vaccines; therapeutics

Online: 26 April 2020 (08:15:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201707.0044.v1

A Comprehensive Technological Survey on Dependable Self-Managing CPS: The Decade of Researches on Correctness and Dependability

Peng Zhou, Kunmean HOU, Zhan Zhang, Decheng Zuo, Jian Dong, Jianjin Li, Haiyin Zhou

Subject: Engineering, Control And Systems Engineering Keywords: cyber physical systems; industry 4.0; MDE; hardware and software co-design; lifetime verification & validation; dependability; correctness; flexibility; self-management; self-adapting; self-healing

Online: 17 July 2017 (10:27:33 CEST)

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Preprint REVIEW | doi:10.20944/preprints201703.0157.v1

Guided Self-Accelerating Airy Beams—A Mini-Review

Yiqi Zhang, Hua Zhong, Milivoj R. Belic, Yanpeng Zhang

Subject: Physical Sciences, Optics And Photonics Keywords: airy beam; harmonic potential; dynamic linear potential; self-Fourier beam; phase; transition; soliton

Online: 20 March 2017 (09:48:40 CET)

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Preprint REVIEW | doi:10.20944/preprints202104.0019.v1

An Overview on Bioconcrete and the Utilization of Microbes in Civil Engineering

Mohammad Rizwan Bhina, Antoni H Wibowo, Kuang Yen Liu, Waseem Khan, Mohammad Salim

Subject: Engineering, Civil Engineering Keywords: bioconcrete; microbes; biomineralization; self-healing; calcite precipitation

Online: 1 April 2021 (12:56:36 CEST)

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Preprint REVIEW | doi:10.20944/preprints202005.0261.v1

An Extensive Review of Health and Economy of Bangladesh Amid Covid-19 Pandemic

Abdul Kader Mohiuddin

Subject: Social Sciences, Government Keywords: domestic violence during lockdown; healthcare denial; poor adherence to self-quarantine; natural Disasters amid Covid-19; repatriation of migrant workers; supply chain crisis

Online: 15 May 2020 (18:09:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202004.0216.v1

Development of a Field-deployable RT-qPCR Workflow for COVID-19 Detection

Raphael Nyaruaba, Bo Zhang, Caroline Muema, Elishiba Muturi, Greater Oyejobi, Jin Xiong, Bei Li, Zhengli Shi, Caroline Mwaliko, Junping Yu, Xiaohong Li, Hongping Wei

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: COVID-19; SARS-CoV-2; field work; community; diagnosis; rapid detection; inactivation; RT-qPCR

Online: 14 April 2020 (08:41:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0023.v1

Effects of Biomimetic Shear Stress by Self-Assembled Gelatin Oleic Nanoparticles Containing Paclitaxel on the Behavior of Cancer Cell Lines in a Microfluidic System

Taehee Kang, Thuy Thi Thanh Tran, Kyung Taek Oh, Han-Gon Choi, Beom-Jin Lee

Subject: Chemistry And Materials Science, Nanotechnology Keywords: gelatin-oleic conjugate; self-assembled biodegradable nanoparticles; biomimetic shear stress; cell dynamic environment; cellular drug delivery; paclitaxel

Online: 4 April 2017 (10:59:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201809.0610.v1

Self-Consciousness and Healthy Personality in Online Shopping Behavior

Jesús Manuel López-Bonilla, Luis Miguel López-Bonilla, Borja Sanz-Altamira

Subject: Business, Economics And Management, Marketing Keywords: self-consciousness; online shopping behavior; technology acceptance model (TAM)

Online: 30 September 2018 (11:31:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0047.v2

Multistage DC-DC Step-Up Self Balanced and Magnetic Component Free Converter for Photovoltaic Applications—Hardware Implementation

Mahajan Sagar Bhaskar, Sanjeevikumar Padmanaban, Frede Blaabjerg

Subject: Engineering, Electrical And Electronic Engineering Keywords: DC-DC; self biased; magnetic component free; multistage; step-up; photovoltaic application

Online: 10 April 2017 (06:14:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201702.0106.v1

A Robust Diffusion Estimation Algorithm with Self-adjusting Step-size in WSNs

Feng Chen, Qing Ye, Xiaodan Shao, Shukai Duan

Subject: Computer Science And Mathematics, Computer Science Keywords: robust diffusion estimation; self-adjusting step-size; non-Gaussian noise; wireless sensor networks

Online: 28 February 2017 (12:38:25 CET)

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Working Paper ARTICLE

Dynamic Real-Time Risk Analytics of Uncontrollable States in Complex Internet of Things Systems: Cyber Risk at the Edge

Petar Radanliev, David De Roure, Max Van Kleek, Pete Burnap, Eirini Anthi, Jason R.C. Nurse, Omar Santos, Rafael Mantilla Montalvo, La’Treall Maddox

Subject: Engineering, Automotive Engineering Keywords: functional dependency; network-based linear dependency modelling; internet of things; micro mort model; goal-oriented approach; transformation roadmap; cyber risk regulations; empirical analysis; cyber risk self-assessment; cyber risk target state.

Online: 25 December 2020 (11:35:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202007.0650.v1

CNN-KCL: Automatic Myocarditis Diagnosis using Convolutional Neural Network Combined with K-means Clustering

Danial Sharifrazi, Roohallah Alizadehsani, Javad Hassannataj Joloudari, Shahab Shamshirband, Sadiq Hussain, Zahra Alizadeh Sani, Fereshteh Hasanzadeh, Afshin Shoaibi, Abdollah Dehzangi, Hamid Alinejad-Rokny

Subject: Computer Science And Mathematics, Computer Science Keywords: Myocarditis; Diagnosis; Convolutional Neural Network; Cardiac MRI; prediction

Online: 26 July 2020 (17:44:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201702.0105.v1

Can A Robot Have Free Will?

Keith D. Farnsworth

Subject: Computer Science And Mathematics, Robotics Keywords: self-organization; downward causation; autocatalytic set; goal-oriented behaviour; autopoiesis; biological computing

Online: 28 February 2017 (12:08:07 CET)

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Preprint REVIEW | doi:10.20944/preprints201904.0162.v1

Advanced Nanotechnologies for Enhancing the Bioavailability of Silymarin: A State of the Art

Alfonso Di Costanzo, Ruggero Angelico

Subject: Chemistry And Materials Science, Nanotechnology Keywords: silymarin; silybin; nanoemulsion; solid lipid nanoparticles; nanostructured lipid carriers; liposome; polymeric particles; self-emulsifying delivery systems; enhanced bioavailability

Online: 15 April 2019 (11:23:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0154.v1

Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory Paradigm of Quantum Fields

L. Montagnier, J. Aïssa, A. Capolupo, T. J. A. Craddock, P. Kurian, C. Lavallee, A. Polcari, P. Romano, A. Tedeschi, G. Vitiello

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: water bridging; dipole waves; coherent states; polymerase chain reaction; DNA amplification; DNA transduction; enzyme catalytic activity; fractal-like self-similarity

Online: 25 April 2017 (04:24:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints201707.0070.v3

A Comparison of the Social-Adaptive Perspective and Functionalist Perspective on Guilt and Shame

Heidi L. Dempsey

Subject: Social Sciences, Psychology Keywords: guilt; shame; emotion; functionalist; social-adaptive; test of self-conscious affect; TOSCA

Online: 7 December 2017 (05:50:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints201906.0028.v1

A General Theory of Autoimmune Disease Causation: Integrating Innate and Adaptive Immunity, Altered Antigen Processing, Sex and Genetic Predispositions, and Microbiome Effects

Robert Root-Bernstein

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: autoimmunity; toll-like receptors; TLR; nucleotide-binding oligomerization domain; NOD1; major histocompatibility complex; MHC; human leukocyte antigens; HLA; proteasome; innate immunity; adaptive immunity; T cells; B cells; antibodies; microbiome; tolerance; self; non-self; antigen processing

Online: 4 June 2019 (10:21:32 CEST)

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Current theories of autoimmunity are diverse, sometimes contradictory, and suffer from incompleteness. Although substantial evidence exists that adaptive and innate immunity, sex, genetic predisposition, and the microbiome all play essential roles in autoimmune disease etiologies and pathogenesis, and that antigen processing is altered during disease induction, no existing theory integrates all of these factors through a single, coherent mechanism. In an attempt to focus the field on the need to elucidate such an integrative mechanism, I propose one possibility here that, if nothing else, helps to identify the nature of the problems that need to be addressed. My theory is that autoimmune diseases are induced by normal immunological responses to unique pairs of complementary antigens, at least one of which is a molecular mimic of a host target. Each antigen in the complementary pair induces a complementary immune response (T or B cell); although each immune response is idiotypic in origin, the antigenic complementarity results in what appears to be an idiotype-anti-idiotype relationship between the responses. Additionally, because of the antigenic complementarity, each immune response mimics one of antigens, abrogating the distinction between self and non-self. If at least one of the antigens mimics a host antigen, then the resulting immunological civil war spreads to a host tissue. Complementary antigens also alter antigen processing so that antigens that would normally be proteolytically digested are presented by the major histocompatibility complex (MHC) to T and B cell receptors inducing a cross-reactive immune response. The resulting civil war is supported by the innate immune system due to the complementarity of the initiating antigens.. Complementary antigens stimulate synergistic toll-like receptors (TLR) and/or nucleotide-binding oligomerization receptors (NOD) resulting in up-regulation of cytokine production and further stimulation of the adaptive immune response. Because the immune responses (e.g., antibodies) mimic the initiating antigens, this synergistic activation of innate immunity becomes chronic. Additionally, TLR and NOD function are highly sensitive to sex hormones, some becoming up-regulated and some down-regulated in the presence of either testosterone or estrogens. This sensitivity explains how sex modifies susceptibility to autoimmune diseases. Genetic mutations in TLR, NOD and MHC further alter antigen presentation and the degree to which antigens stimulate an immune response explaining how genetics also modifies susceptibility. Finally, sex hormones also alter the host microbiome, which in turn modulates autoimmune disease risk by shaping the immunological nature of self and by mediating susceptibility to microbial infection. Moreover, it appears that the microbiome camouflages itself from the immune system by mimicking the host antigenic repertoire; the mimicry between the antigens of the microbiome and the host results in selective attacks on microbiome constituents concomitant with any autoimmune attack on host tissues. This antigenic complementarity theory thereby integrates all major elements known to affect, or be affected by, autoimmune diseases and provides a set of testable implications.

Preprint REVIEW | doi:10.20944/preprints201801.0167.v1

Molecular imaging modalities using nanoprobes for cancer diagnosis

Daryoush Shahbazi-Gahrouei, Pegah Moradi Khaniabadi, Bita Moradi khaniabadi, Saghar Shahbazi-Gahrouei, Mona Fazel

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: molecular imaging; nanoparticles; cancer diagnosis; imaging modalities

Online: 18 January 2018 (05:12:13 CET)

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Preprint REVIEW | doi:10.20944/preprints201703.0031.v2

Self-Referential Encoding on Modules of Anticodon Pairs—Roots of the Biological Flow System

Romeu Cardoso Guimarães

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: genetic code; tRNA dimers; self-reference; modularity; error-compensation; metabolism chronology; protein stability; punctuation system

Online: 17 March 2017 (04:55:46 CET)

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Preprint REVIEW | doi:10.20944/preprints202007.0516.v1

COVID-19 Clot: What Is It? Why in the Lungs? Extracellular Histone, “Auto-Activation” of Prothrombin, Emperipolesis, Megakaryocytes, “Self-Association” of Von Willebrand Factor and Beyond

Nadarajah Varatharajah

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Megakaryocyte, IFITM3, VWF, ADAMTS13, emperipolesis, self-association, unfractionated heparin (UFH), histone, NETs, Thrombin

Online: 22 July 2020 (11:03:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0166.v1

Near-Infrared Spectroscopy-based Detector in Application of Intensive Care Unit Clinics

Ting Li, Fulin Zhong, Zishan Deng, Boan Pan, Zebin Li

Subject: Medicine And Pharmacology, Other Keywords: optoelectronic sensor; near-infrared spectroscopy; thrombus diagnosis; shock monitoring; fatigue evaluation

Online: 26 April 2017 (06:05:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0135.v1

Holistic Context-Sensitivity for Run-time Optimization of Flexible Manufacturing Systems

Sebastian Scholze, Jose Barata, Dragan Stokic

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: context sensitivity; cyber physical systems; flexible manufacturing system; process optimization; self-learning systems; SOA

Online: 28 December 2016 (11:13:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202305.0926.v1

An Organizational Diagnosis for Change Readiness: A Case of the Department of Special Education Government of Punjab

Sahib Khan, Muhammad Uzair Ul Hassan, Iram Parveen, Rozita Abdul Mutalib, Masood Ahmad Khan

Subject: Business, Economics And Management, Human Resources And Organizations Keywords: Organizational Diagnosis; Special Education; Readiness for change; Weisbord’s model

Online: 12 May 2023 (10:28:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201705.0004.v1

Data–Driven Fault Diagnosis of a Wind Farm Benchmark Model

Silvio Simani, Paolo Castaldi, Saverio Farsoni

Subject: Engineering, Control And Systems Engineering Keywords: fault diagnosis; analytical redundancy; fuzzy logic; neural networks; data-driven approaches; nonlinear geometric approach; wind farm benchmark simulator

Online: 1 May 2017 (07:53:08 CEST)

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Preprint REVIEW | doi:10.20944/preprints202109.0149.v1

New Perspectives in Imaging of Uveal Melanoma

Malgorzata Solnik, Natalia Paduszynska, Anna M. Czarnecka, Kamil J. Synoradzki, Yacoub A. Yousef, Tomasz Choragiewicz, Robert Rejdak, Mario Damiano Toro, Katarzyna Dyndor, Michal Fiedorowicz

Subject: Medicine And Pharmacology, Ophthalmology Keywords: uveal melanoma; diagnosis; imaging; MRI; PET; CT; SPECT; OCT; ultrasonography

Online: 8 September 2021 (12:38:40 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints202003.0415.v1

How to Further Reduce the Risk of Serious COVID-19 Infections: Exploiting the Fragile Viral Envelope and the Self-Cleaning Mechanisms of Our Respiratory System

Viola Vogel

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: coronavirus; self-defense mechanisms of the human body

Online: 29 March 2020 (03:12:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201711.0199.v2

Self-Sampling for HPV Testing: Increased Cervical Cancer Screening Participation and Incorporation in International Screening Programs

Sarah Gupta, Christina Palmer, Elisabeth M. Bik, Juan P. Cardenas, Harold Nuñez, Laurens Kraal, Sara Bird, Jennie Bowers, Alison Smith, Nathaniel A. Walton, Audrey D. Goddard, Daniel E. Almonacid, Jessica Richman, Zachary S. Apte

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: human papillomavirus; HPV; cervical cancer; cancer screening; self-sampling; vaginal microbiome

Online: 1 December 2017 (07:19:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0078.v1

An Overview and Evaluation of Recent Machine Learning Imputation Methods Using Cardiac Imaging Data

Yuzhe Liu, Vanathi Gopalakrishnan

Subject: Computer Science And Mathematics, Computer Science Keywords: missing value imputation; machine learning; decision tree imputation; k-nearest neighbors imputation; self-organizing map imputation

Online: 15 December 2016 (08:27:13 CET)

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Preprint REVIEW | doi:10.20944/preprints202004.0372.v1

Pathogenesis, Diagnosis and Possible Therapeutic Options for COVID-19

Yusha Araf

Subject: Biology And Life Sciences, Virology Keywords: COVID-19; Diagnosis; Pathogenesis; Treatment; SARS-CoV-2

Online: 21 April 2020 (04:44:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0073.v1

Oxide Self-Flux in Optical Floating Zone Crystal Growth of Nickel Niobate (NiNb₂O₆)

Timothy J. S. Munsie, Anna Millington, Graeme M. Luke, Hanna A. Dabkowska

Subject: Physical Sciences, Condensed Matter Physics Keywords: optical floating zone; self flux; crystal growth; oxide growth

Online: 13 April 2017 (06:18:11 CEST)

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Preprint REVIEW | doi:10.20944/preprints202305.1084.v1

Lysosomal Cleavable Peptide Linkers in Antibody-Drug Conjugates

Seetharamsing Balamkundu, Chuan Fa Liu

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: antibody-drug conjugate; lysosome; cathepsin; legumain; self-immolation; payload release; peptidomimetic; linker

Online: 16 May 2023 (04:51:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201710.0141.v1

A Case Study on Large Deformation Failure Mechanism of Coal given Chamber and Invention of a New Wall-Mounted Coal Bunker in Xiashijie Coal Mine with Soft, Swelling Floor Rock

Xingkai Wang, Wenbing Xie, Shengguo Jing, Jianbiao Bai, Zhili Su

Subject: Engineering, Control And Systems Engineering Keywords: Vertical coal bunker; Coal given chamber; Floor heave; Wall-mounted coal bunker; Reinforcement; Self-bearing system

Online: 20 October 2017 (15:31:57 CEST)

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Serious damage caused by floor heave in the coal given chamber of a vertical coal bunker is one of the challenges faced in underground coal mines. Engineering practice shows that it is more difficult to maintain the coal given chamber (CGC) than a roadway. More importantly, repairing the CGC during mining practice will pose major safety risks and reduce production. Based on the case of the serious collapse that occurred in the bearing structure of the CGC at the lower part of the 214# coal bunker in Xiashijie mine, China, this work analysed (i) the main factors influencing floor heave and (ii) the failure mechanism of the load-bearing structure in the CGC using FLAC^2D numerical models and expansion experiment. The analysis results indicate that: the floor heave, caused mainly by mine water, is the basic reason leading to the instability and repeated failure of the CGC in the 214# coal bunker. Then a new coal bunker, without building the CGC, is proposed and put into practice to replace the 214# coal bunker. The FLAC^3D software program is adopted to establish the numerical model of the wall-mounted coal bunker (WMCB), and the stability of the rock surrounding the WMCB is simulated and analysed. The results show that: (1) the rock surrounding the sandstone segment is basically stable. (2) The surrounding rock in the coal seam segment, which moves into the inside of the bunker, is the main zone of deformation for the entire rock mass surrounding the bunker. Then the surrounding rock is controlled effectively by means of high-strength bolt–cable combined supporting technology. According to the geological conditions of the WMCB, the self-bearing system, which includes (i) H-steel beams, (ii) H-steel brackets, and (iii) self-locking anchor cables, is established and serves as a substitute for the CGC to transfer the whole weight of the bunker to stable surrounding rock. The stability of the new coal bunker has been verified by field testing, and the coal mine has gained economic benefit to a value of 158.026174 million RMB over three years. The new WMCB thus made production more effective and can provide helpful references for construction of vertical bunkers under similar geological conditions.

Preprint REVIEW | doi:10.20944/preprints202108.0351.v1

Review of Materials and Fabrication Methods for Flexible Nano and Micro-Scale Physical Property Sensors

Anesu Nyabadza, Mercedes Vázquez, Shirley Coyle, Brian Fitzpatrick, Dermot Brabazon

Subject: Engineering, Electrical And Electronic Engineering Keywords: Flexible sensors; additive manufacturing; 3D printing; self-healing; nanocomposites; advanced manufacturing

Online: 17 August 2021 (08:30:46 CEST)

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Preprint REVIEW | doi:10.20944/preprints202003.0103.v2

MERS-CoV and SARS-CoV Infections in Animals: A Systematic Review and Meta-Analysis of Prevalence Studies

D. Katterine Bonilla-Aldana, María C. Cardona-Trujillo, Alejandra García-Barco, Yeimer Holguin-Rivera, Isabella Cortes-Bonilla, Hugo A. Bedoya-Arias, Leidy Jhoana Patiño-Cadavid, Juan David Tamayo-Orozco, Alberto Paniz-Mondolfi, Lysien I. Zambrano, Kuldeep Dhama, Ranjit Sah, Ali A. Rabaan, Graciela J. Balbin-Ramon, Alfonso J. Rodriguez-Morales

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Coronavirus; SARS-CoV; MERS-CoV; serology; molecular diagnosis; reservoir; public health

Online: 19 May 2020 (04:13:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0091.v1

Shock Pulse Index and Its Application in the Fault Diagnosis of Rolling Element Bearings

Peng Sun, Yuhe Liao, Jing Lin

Subject: Engineering, Mechanical Engineering Keywords: fault diagnosis; shock pulse index; maximum correlated kurtosis deconvolution; teager energy operator; rolling element bearings

Online: 20 January 2017 (04:12:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints201705.0197.v1

Evaluation of an Educational Videogame on Mathematics Achievement in First Grade Students

Kimberly Hieftje, Tyra Pendergrass, Tassos C. Kyriakides, Walter Gilliam, Lynn Fiellin

Subject: Computer Science And Mathematics, Computer Science Keywords: mathematics; videogame; education; self-competency; randomized controlled trial

Online: 29 May 2017 (10:32:30 CEST)

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Preprint REVIEW | doi:10.20944/preprints201807.0033.v1

Dynamic DNA Origami Devices

Heini Ijäs, Sami Nummelin, Boxuan Shen, Mauri A. Kostiainen, Veikko Linko

Subject: Chemistry And Materials Science, Nanotechnology Keywords: DNA nanotechnology; DNA origami; self-assembly; molecular devices; mechanical movement; robotics

Online: 3 July 2018 (10:03:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201803.0114.v1

Hydrophilic Self-Replenishing Coatings with Long-Term Water Stability for Anti-Fouling Applications

Isabel Jiménez-Pardo, Leendert G.J. van der Ven, Rolf A.T.M. van Benthem, Gijsbertus de With, A. Catarina C. Esteves

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: self-replenishing; anti-fouling; hydrophilic coatings; polycarbonate; mPEG; dangling chains

Online: 15 March 2018 (04:54:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints201803.0251.v1

Examining Self-Disclosure on Social Networking Sites: A Flow Theory and Privacy Perspective

Aseda Mensah, George Oppong Appiagyei Ampong, Adolph Sedem Yaw Adu, John Agyekum Addae, Osaretin Kayode Omoregie, Kwame Simpe Ofori

Subject: Social Sciences, Media Studies Keywords: self-disclosure; social networking sites; flow; privacy concerns; structural equation modeling; Ghana

Online: 29 March 2018 (14:35:35 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints201702.0031.v1

Krzysztof Z. Sokalski

Subject: Physical Sciences, Condensed Matter Physics Keywords: scaling; self-similarity; stochastic processes

Online: 10 February 2017 (10:02:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints201801.0003.v1

A Paradox of Unity

Jens V. Fischer

Subject: Computer Science And Mathematics, Analysis Keywords: Dirac impulse; generalized functions; tempered distributions; paradox of unity; Dirac's delta squared; quantum mechanics; Born's principle of reciprocity; scalar self-reciprocity

Online: 2 January 2018 (06:47:57 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202002.0156.v1

Clinical Reports on Early Diagnosis of Novel Coronavirus (2019-nCoV) Pneumonia in Stealth Infected Patients

Yang Zhou, Le Yang, Ming Han, Mingqiang Huang, Xuedong Sun, Weidong Zhen, Junqing Xu, Jinhong Wang, Wei Han

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: 2019-nCoV; Chest CT; Epidemic; Diagnosis

Online: 12 February 2020 (09:14:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints201710.0056.v1

Conditioning Factors in the Transition Process to the Self-Care of Women with AIDS

Claudia Regina de Andrade Arrais Rosa, Simony Fabíola Lopes Nunes, Regiane Silva de Jesus, Francisco Dimitre Rodrigo Pereira Santos, Leila Rute Oliveira Gurgel do Amaral, Nilviane Pires Silva Sousa, Daniel Costa Duarte, Allan Kardec Barros Duailibe Filho

Subject: Social Sciences, Psychology Keywords: nursing theory; self-care women; HIV

Online: 10 October 2017 (02:55:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201709.0100.v1

Cut-off Values of Hematologic Parameters to Predict the Number of Alpha Genes Deleted in Subjects with Deletional Alpha Thalassemia

Diego Velasco-Rodríguez, Carlos Blas, Juan-Manuel Alonso-Domínguez, Gala Vega, Carlos Soto, Aránzazu García-Raso, Pilar Llamas-Sillero

Subject: Medicine And Pharmacology, Hematology Keywords: alpha; thalassemia; deletional; cut-off; number of genes; microcytic anemia; differential diagnosis

Online: 21 September 2017 (04:47:16 CEST)

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Preprint REVIEW | doi:10.20944/preprints202011.0216.v1

Diagnosis of Composite Materials in Aircraft Applications–Brief Survey of Recent Literature

Muflih Alhammad, Luca Zanotti Fragonara, Nicolas P Avdelidis

Subject: Engineering, Automotive Engineering Keywords: Failure Diagnosis; Aircraft Applications; Composite Materials; Non-Destructive Testing (NDT) Techniques

Online: 5 November 2020 (14:53:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0408.v1

Maritime Workers’ Quality of Life: Organizational Culture, Self-efficacy, and Perceived Fatigue

Jae hee Kim, Soong-nang Jang

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: quality of work life; organizational culture; organizational support; self-efficacy; maritime workers; culture-work-health model

Online: 23 July 2018 (10:00:06 CEST)

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Preprint REVIEW | doi:10.20944/preprints201707.0003.v1

Chronic Wasting Disease: Evolution of Diagnostic Testing for a Naturally Occurring Prion Disease

Nicholas J. Haley, Juergen A. Richt

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: prion, cervids, PMCA, RT-QuIC, diagnosis

Online: 3 July 2017 (17:34:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints202201.0386.v1

Self-Healing Systems on Anodes for Next Generation Energy Storage Devices

Neslihan Yuca, Ilknur Kalafat, Emre Guney, Busra Cetin, Omer Suat Taskin

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: self-healing; polymers; batteries; silicon anodes

Online: 25 January 2022 (15:37:52 CET)

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Preprint REVIEW | doi:10.20944/preprints202002.0261.v2

Phase Transitions in Virology

Ricard Sole, Josep Sardanyes, Santiago F. Elena

Subject: Biology And Life Sciences, Virology Keywords: epidemics; molecular replicators; mutation; quasispecies; recombination; self-assembly; phase transitions

Online: 29 October 2020 (09:30:44 CET)

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Viruses have established symbiotic relationships with almost every other living organism on Earth and at all levels of biological organisation, from other viruses up to entire ecosystems. In most cases, peacefully coexisting with their hosts, but in most relevant cases, parasitising them and inducing diseases. Viruses are playing an essential role in shaping the eco-evolutionary dynamics of their hosts, and have been also involved in some of the major evolutionary innovations either by working as vectors of genetic information or by being themselves coopted by the host into their genomes. Viruses can be studied at different levels of biological organisation, from the molecular mechanisms of genome replication, gene expression and encapsidation, to global pandemics. All these levels are different and yet connected through the presence of threshold conditions allowing for the formation of a capsid, the loss of genetic information or epidemic spreading. These thresholds, as it occurs with temperatures separating phases in a liquid, define sharp qualitative types of behaviour. These {\em phase transitions} are very well known in Physics. They have been studied by means of simple, but powerful models able to capture their essential properties, allowing to understand them. Can the physics of phase transitions be an inspiration for our understanding of viral dynamics at different scales? Here we review well-known examples of transition phenomena in virology and their simplest mathematical modelling approaches. We suggest that the advantages of abstract, simplified pictures used in Physics are also the key to properly understand the origins and evolution of complexity in viruses. By means of several examples, we explore this multilevel landscape and how minimal models provide deep insights into a diverse array of problems. The relevance of these transitions in connecting dynamical patterns across levels and their evolutionary and clinical implications are outlined.

Preprint ARTICLE | doi:10.20944/preprints202004.0350.v1

Cymatics Inspired Self-Cleaning Mechanism for Solar Panels

Edwin Babu, Sumith Yesudasan, Sibi Chacko

Subject: Engineering, Mechanical Engineering Keywords: solar panel; laminatel vibrations; self-cleaning; cymatics

Online: 19 April 2020 (13:51:32 CEST)

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Preprint REVIEW | doi:10.20944/preprints202101.0471.v1

Fluorescent Aptamers for Detection and Treatment of Pathogenic Bacteria and Cancer

Aarushi Sharma, Grace Ramena

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: aptamer; aptasensor; diagnosis; imaging; sequencing; therapeutics; probes; fluorescence; pathogenic bacteria; cancer cells; monoclonal antibodies; SELEX; nucleic acids

Online: 25 January 2021 (10:18:16 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202211.0016.v1

What Primary Care Practitioners Need to Know about the New NICE Guideline for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in Adults

Caroline Claire Kingdon, Adam Lowe, Charles Shepherd, Luis Nacul

Subject: Public Health And Healthcare, Primary Health Care Keywords: ME/CFS; ME; understanding; diagnosis; management; disabling; stigma

Online: 1 November 2022 (04:27:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints201809.0390.v1

Effective Features to Classify Ovarian Cancer Data in Internet of Medical Things

Mohamed Elhoseny, Gui-Bin Bian, S.K. Lakshmanaprabu, K. Shankar, Amit Kumar Singh, Wanqing Wu

Subject: Engineering, Control And Systems Engineering Keywords: Ovarian Cancer; Features Classification; Self-Organizing Map; Optimal Neural Networks; Adaptive Harmony Search Optimization; Internet of Things

Online: 19 September 2018 (16:15:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201709.0124.v1

Evaluation of Electrical Tree Degradation in Cable Insulation using Weibull Process of Propagation Time

Donguk Jang, Seonghee Park

Subject: Engineering, Electrical And Electronic Engineering Keywords: partial discharge; Weibull distribution; XLPE cable; electric tree; diagnosis

Online: 25 September 2017 (16:47:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints201907.0196.v1

Pathological Mechanisms Underlying Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Daniel Missailidis, Sarah Annesley, Paul Fisher

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, ME/CFS, diagnosis, metabolism, mitochondria, inflammation, immune system, signaling, gut microbiota.

Online: 16 July 2019 (12:41:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201801.0011.v1

Critical Nutrient Concentrations and DRIS Norms for Pinus patula

Agustina Sánchez-Parada, Miguel Ángel López-López, Armando Gómez-Guerrero, Marlín Pérez-Suárez

Subject: Biology And Life Sciences, Forestry Keywords: plant nutrition; chemical fertilization; nutrient diagnosis; forest plantation; foliar nutrients

Online: 2 January 2018 (10:25:46 CET)

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Preprint REVIEW | doi:10.20944/preprints202102.0345.v1

Advanced Selection Materials in Solar Cell Efficiency and their Properties- A Comprehensive Review

Ibrahim Alarifi

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Copper indium gallium selenide layers; Solar cell efficiency; Self-cleaning; Superhydrophobic coatings; Vapour deposition technique

Online: 17 February 2021 (08:23:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints202006.0031.v3

A Fully Automated Deep Learning-based Network For Detecting COVID-19 from a New And Large Lung CT Scan Dataset

Mohammad Rahimzadeh, Abolfazl Attar, Seyed Mohammad Sakhaei

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Deep learning; Convolutional Neural Network; Coronavirus; COVID-19; radiology; CT scan; Medical image analysis; Automatic medical diagnosis; lung CT scan dataset

Online: 5 September 2020 (03:36:20 CEST)

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Preprint REVIEW | doi:10.20944/preprints202203.0285.v1

Large Power Transformers: Time Now for Addressing Their Monitoring and Failure Investigation Techniques

Jonathan Velasco Costa, Diogo F.F. Silva, P.J. Costa Branco

Subject: Engineering, Electrical And Electronic Engineering Keywords: Large power transformer; condition monitoring; transformer fault diagnosis; diagnostic techniques; mechanical or electrical integrity of the core and windings

Online: 21 March 2022 (10:47:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0106.v1

A Comparative Study of the Causes and Methods of Completed Suicide Referred to Legal Medicine Organization in Bushehr Province, South of Iran, 2006-2015

Alireza Raeisi, Mahmo]od Montazeri, Hiyam Hosseini

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: completed suicide; hanging out; self-Immolation; Bushehr; Iran

Online: 24 January 2017 (04:16:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints201804.0188.v1

A Fault Diagnosis Scheme of Gear Vibration Signal Based on Variational Mode Decomposition and Detrended Fluctuation Analysis

Sinian Hu, Han Xiao, Cancan Yi

Subject: Engineering, Mechanical Engineering Keywords: variational mode decomposition; detrended fluctuation analysis; heavy gearbox; fault diagnosis

Online: 16 April 2018 (05:35:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints201807.0478.v1

Risk Stratification on Pheochromocytoma and Paraganglioma from Laboratory and Clinical Medicine

Noriko Kimura, Kazuhiro Takekoshi, Mitsuhide Naruse

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: pheochromocytoma; paraganglioma; GAPP; metastasis; prognosis; catecholamine; gene mutation; immunohistochemistry; pathology; diagnosis

Online: 25 July 2018 (11:41:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0592.v1

Perceived Organizational Support and Career Adaptability as Predictors of Self and Environmental-career Exploration: An Empirical Investigation in China

Yin Ma, Shih-Chih Chen, Athapol Ruangkanjanases

Subject: Business, Economics And Management, Business And Management Keywords: higher education expansion; sustainable employment; perceived organizational support; career adaptability; self-exploration; environment exploration; sustainable career guidance; sustainability competencies

Online: 24 July 2020 (14:12:38 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202008.0574.v2

An Engineering Theory of Evolution

Simeon Castle, Claire Grierson, Thomas Gorochowski

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: evolution; evotype; engineering theory; genotype-phenotype maps; directed evolution; selection; synthetic biology; bioengineering; evolvability; self-adaptive systems

Online: 9 December 2020 (10:51:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints201802.0063.v1

An Experimental Study on Static and Dynamic Strain Sensitivity of Smart Concrete Sensors Doped with Carbon Nanotubes for SHM of Large Structures

Andrea Meoni, Antonella D'Alessandro, Austin Downey, Enrique García-Macías, Marco Rallini, A. Luigi Materazzi, Luigi Torre, Simon Laflamme, Rafael Castro-Triguero, Filippo Ubertini

Subject: Engineering, Civil Engineering Keywords: smart concrete sensors; self-sensing materials; structural health monitoring; strain sensitivity; carbon nanotubes; cement-based materials

Online: 7 February 2018 (13:00:33 CET)

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Preprint HYPOTHESIS | doi:10.20944/preprints202003.0238.v1

A Feedback Loop Between Human Self-Domestication and Dog Domestication Contributing to Language Evolution?

Antonio Benítez-Burraco, Daniela Pörtl, Christoph Jung

Subject: Social Sciences, Behavior Sciences Keywords: dog domestication; human self-domestication; aggression; prosociality; language evolution; cognitive disorders

Online: 15 March 2020 (02:24:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202208.0017.v1

The Relationship between Consuming Fashion and Self-Confidence on the Buying Behaviour in the Clothing Market as a Mediator

Milad Zam, Mohammadhosein Tavakoli, Hasan Ramezanian, Amin Rezasoltani

Subject: Business, Economics And Management, Marketing Keywords: Interest in modem personal taste; utilitarianism; new fashion products; self-confidence; fashion buying behaviour

Online: 1 August 2022 (09:40:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201804.0109.v2

Dissolved Gas Analysis Principle-Based Intelligent Approaches to Fault Diagnosis and Decision Making for Large Oil-Immersed Power Transformers: A Survey

Lefeng Cheng, Tao Yu

Subject: Engineering, Electrical And Electronic Engineering Keywords: power transformer; fault diagnosis and decision; dissolved gas analysis; intelligent algorithms; reliability assessment; hybrid network; preventive electrical tests

Online: 11 April 2018 (08:58:29 CEST)

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Compared with conventional methods of fault diagnosis for power transformers, which have defects such as imperfect encoding and too absolute encoding boundaries, this paper systematically discusses various intelligent approaches applied in fault diagnosis and decision making for large oil-immersed power transformers based on dissolved gas analysis (DGA), including expert system (EPS), artificial neural network (ANN), fuzzy theory, rough sets theory (RST), grey system theory (GST), swarm intelligence (SI) algorithms, data mining technology, machine learning (ML), and other intelligent diagnosis tools, and summarizes existing problems and solutions. From this survey, it is found that a single intelligent approach for fault diagnosis can only reflect operation status of the transformer in one particular aspect, causing various degrees of shortcomings that cannot be resolved effectively. Combined with the current research status in this field, the problems that must be addressed in DGA-based transformer fault diagnosis are identified, and the prospects for future development trends and research directions are outlined. This contribution presents a detailed and systematic survey on various intelligent approaches to faults diagnosing and decisions making of the power transformer, in which their merits and demerits are thoroughly investigated, as well as their improvement schemes and future development trends are proposed. Moreover, this paper concludes that a variety of intelligent algorithms should be combined for mutual complementation to form a hybrid fault diagnosis network, such that avoiding these algorithms falling into a local optimum. Moreover, it is necessary to improve the detection instruments so as to acquire reasonable characteristic gas data samples. The research summary, empirical generalization and analysis of predicament in this paper provide some thoughts and suggestions for the research of complex power grid in the new environment, as well as references and guidance for researchers to choose optimal approach to achieve DGA-based fault diagnosis and decision of the large oil-immersed power transformers in preventive electrical tests.

Preprint ARTICLE | doi:10.20944/preprints201802.0192.v1

Self-Tuning Method for Increasing Reliability in Obstacle Detection based on Internet-of-Things LiDAR Sensor Models

Fernando Castaño, Gerardo Beruvides, Alberto Villalonga, Rodolfo Haber

Subject: Computer Science And Mathematics, Computer Science Keywords: LiDAR sensors reliability; Internet of Things, self-turning parametrization; k-nearest neighbors, driven-assistance simulator

Online: 28 February 2018 (11:26:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints201711.0193.v1

A Quantum Hybrid PSO Combined with Fuzzy K-NN Approach to Feature Selection and Cell Classification in Cervical Cancer Detection

Abdullah M. Iliyasu, Chastine Fatichah

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: computational intelligence; quantum hybrid intelligent systems; quantum machine learning; medical image processing; disease diagnosis; Fuzzy k-NN; Quantum-behaved PSO; cervical smear images; cancer detection

Online: 30 November 2017 (07:21:00 CET)

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Preprint REVIEW | doi:10.20944/preprints201909.0211.v1

MOOCs at the Crossroads: A Literature Review and Reflection Drawing upon Discourse Analysis

Laila Mohebi, Marcelo F. Ponce

Subject: Social Sciences, Education Keywords: MOOCs; distance education; self-directed learning; self-defined learning pathways; 21st century abilities

Online: 18 September 2019 (17:00:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202111.0123.v1

Professional Self-Concept and Self-Confidence for Nurses Dealing with COVID-19 Patients

Nabeel F. Allobaney, Nidal F. Eshah, Ahmad A. Abujaber, Abdulqadir J. Nashwan

Subject: Public Health And Healthcare, Nursing Keywords: COVID-19; nurses; self-concept; self-confidence; professional practice

Online: 5 November 2021 (14:12:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints201712.0026.v2

Fault Diagnosis of Induction Machines in Transient Regime Using Current Sensors with an Optimized Slepian Window

Jordi Burriel-Valencia, Ruben Puche-Panadero, Javier Martinez-Roman, Angel Sapena-Bañó, Manuel Pineda-Sanchez

Subject: Engineering, Electrical And Electronic Engineering Keywords: fault diagnosis; condition monitoring; short time Fourier transform; slepian window; prolate spheroidal wave functions; discrete prolate spheroidal sequences; time-frequency distributions

Online: 6 December 2017 (05:34:29 CET)

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