Preprint Case Report Version 1 This version is not peer-reviewed

Clinical Reports on Early Diagnosis of Novel Coronavirus (2019-nCoV) Pneumonia in Stealth Infected Patients

Version 1 : Received: 11 February 2020 / Approved: 12 February 2020 / Online: 12 February 2020 (09:14:56 CET)

How to cite: Zhou, Y.; Yang, L.; Han, M.; Huang, M.; Sun, X.; Zhen, W.; Xu, J.; Wang, J.; Han, W. Clinical Reports on Early Diagnosis of Novel Coronavirus (2019-nCoV) Pneumonia in Stealth Infected Patients. Preprints 2020, 2020020156 (doi: 10.20944/preprints202002.0156.v1). Zhou, Y.; Yang, L.; Han, M.; Huang, M.; Sun, X.; Zhen, W.; Xu, J.; Wang, J.; Han, W. Clinical Reports on Early Diagnosis of Novel Coronavirus (2019-nCoV) Pneumonia in Stealth Infected Patients. Preprints 2020, 2020020156 (doi: 10.20944/preprints202002.0156.v1).

Abstract

An outbreak of novel coronavirus(2019-nCoV) that began in Wuhan, China, is rapidly spreading to all over China, and gradually to multiple countries. Regarding to put the epidemic prevention and spread under the control, early identification and diagnosis play a critical role. Patients with initially no or mild symptoms of Novel Coronavirus Pneumonia (2019-nCoV), namely “stealth” infection, often lack of typical clinical evidence to establish the diagnosis. Based on the clinical analysis of 4 cases in stealth infection, the results of this study highlight that early diagnosis requires a combination of epidemiological history, clinical manifestations, early chest CT examination, and 2019-nCoV RNA test (nucleic acid test), with particular emphasis on definite epidemiological history and early chest CT findings when positive nucleic acid tests lag behind.

Subject Areas

2019-nCoV; Chest CT; Epidemic; Diagnosis

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