New Perspectives in Imaging of Uveal Melanoma

Malgorzata Solnik; Natalia Paduszynska; Anna M. Czarnecka; Kamil J. Synoradzki; Yacoub A. Yousef; Tomasz Choragiewicz; Robert Rejdak; Mario Damiano Toro; Katarzyna Dyndor; Michal Fiedorowicz

doi:10.20944/preprints202109.0149.v1

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preprints.org > medicine and pharmacology > ophthalmology > doi: 10.20944/preprints202109.0149.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

New Perspectives in Imaging of Uveal Melanoma

Version 1 : Received: 7 September 2021 / Approved: 8 September 2021 / Online: 8 September 2021 (12:38:40 CEST)

How to cite: Solnik, M.; Paduszynska, N.; Czarnecka, A.M.; Synoradzki, K.J.; Yousef, Y.A.; Choragiewicz, T.; Rejdak, R.; Toro, M.D.; Dyndor, K.; Fiedorowicz, M. New Perspectives in Imaging of Uveal Melanoma. Preprints 2021, 2021090149. https://doi.org/10.20944/preprints202109.0149.v1 Solnik, M.; Paduszynska, N.; Czarnecka, A.M.; Synoradzki, K.J.; Yousef, Y.A.; Choragiewicz, T.; Rejdak, R.; Toro, M.D.; Dyndor, K.; Fiedorowicz, M. New Perspectives in Imaging of Uveal Melanoma. Preprints 2021, 2021090149. https://doi.org/10.20944/preprints202109.0149.v1

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MDPI and ACS Style

Solnik, M.; Paduszynska, N.; Czarnecka, A.M.; Synoradzki, K.J.; Yousef, Y.A.; Choragiewicz, T.; Rejdak, R.; Toro, M.D.; Dyndor, K.; Fiedorowicz, M. New Perspectives in Imaging of Uveal Melanoma. Preprints 2021, 2021090149. https://doi.org/10.20944/preprints202109.0149.v1

APA Style

Solnik, M., Paduszynska, N., Czarnecka, A.M., Synoradzki, K.J., Yousef, Y.A., Choragiewicz, T., Rejdak, R., Toro, M.D., Dyndor, K., & Fiedorowicz, M. (2021). New Perspectives in Imaging of Uveal Melanoma. Preprints. https://doi.org/10.20944/preprints202109.0149.v1

Chicago/Turabian Style

Solnik, M., Katarzyna Dyndor and Michal Fiedorowicz. 2021 "New Perspectives in Imaging of Uveal Melanoma" Preprints. https://doi.org/10.20944/preprints202109.0149.v1

Abstract

Uveal melanoma is the most common primary intraocular malignancy in adults characterized by insidious onset and poor prognosis strongly associated with tumor size and the presence of distant metastases, most commonly in the liver. Contrary to most tumor identification, biopsy followed by pathological exam is not recommended in ophthalmic oncology. Therefore, early and non-invasive diagnosis is essential to enhance patients’ chances for early treatment possibilities. We reviewed imaging modalities currently used in the diagnosis of uveal melanoma, i.e., fundus imaging, ultrasonography (US), optical coherence tomography (OCT), single-photon emission computed tomography (SPECT), positron emission tomography/computed tomography (PET/CT), magnetic resonance imaging (MRI), fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA), fundus autofluorescence (FAF). The principle of imaging techniques was briefly explained, along with their role in the diagnostic process and a summary of their advantages and limitations. Further, the experimental data and the advancements in imaging modalities were searched. We described their innovations, showed current usage and research, and explained the possibilities of utilizing them to diagnose uveal melanoma and their potential application in personalized medicine such as theranostics.

Keywords

uveal melanoma; diagnosis; imaging; MRI; PET; CT; SPECT; OCT; ultrasonography

Subject

Medicine and Pharmacology, Ophthalmology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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