Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Pathogenesis, Diagnosis and Possible Therapeutic Options for COVID-19

Version 1 : Received: 19 April 2020 / Approved: 21 April 2020 / Online: 21 April 2020 (04:44:40 CEST)

A peer-reviewed article of this Preprint also exists.

Journal reference: Journal of Clinical and Experimental Investigations 2020, 11, em00755
DOI: 10.29333/jcei/8564


The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread so rapidly and severely affected the people of almost every country in the world. The highly contagious nature of this virus makes it difficult to take control of the present pandemic situation. With no specific treatment available, the coronavirus disease 2019 (COVID-19) presents a threat to people of all ages including the elderly people and people with other medical complications as a vulnerable group to this disease. Better understanding of viral pathogenesis, appropriate preventive measures, early diagnosis and supportive treatments of the infected patients are now the general solutions to fight against this viral transmission. But, as an emerging disease, most about it remains still poorly understood. This article holds an overview on the origin and structure, pathogenesis, diagnosis and possible therapeutic options for the causative agent, SARS-CoV-2 and disease, COVID-19. However, few therapeutic options, laboratory experiments and other strategies proposed here need to be further clinically tested.


COVID-19; Diagnosis; Pathogenesis; Treatment; SARS-CoV-2



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