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Working Paper ARTICLE

Seroprevalence of SARS-CoV-2 Infection Among Occupational Groups from Bucaramanga Metropolitan Area, Colombia

Claudia C. Colmenares-Mejía, Norma Serrano-Díaz, Doris C. Quintero-Lesmes, Ligia Meneses, Isail Salazar Acosta, Álvaro J. Idrovo, Duván Y. Sanabria-Echeverry, Helmer Cordero-Rebolledo, Víctor Castillo

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Seroepidemiologic Studies; Prevalence; Coronavirus Infections; Occupational Exposure; Occupational Health

Online: 25 March 2021 (15:11:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0097.v1

Genetic Diversity and Population Structure in a Regional Collection of Kersting’s Groundnut (Macrotyloma geocarpum (Harms) Maréchal & Baudet)

Konoutan M. Kafoutchoni, Eric E. Agoyi, Symphorien Agbahoungba, Achille E. Assogbadjo, Clément Agbangla

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: orphan crop; genotyping-by-sequencing; inbreeding; pre-breeding; population genetics; DArTseq; isolation by distance

Online: 4 September 2020 (11:11:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0107.v1

On the Redox-Activity and Health-Effects of Atmospheric Primary and Secondary Aerosol: Phenomenology

Francesca Costabile, Stefano Decesari, Roberta Vecchi, Franco Lucarelli, Gabriele Curci, Dario Massabò, Matteo Rinaldi, Maurizio Gualtieri, Emanuela Corsini, Elena Menegola, Silvia Canepari, Lorenzo Massimi, Stefania Argentini, Maurizio Busetto, Gianluca Di Iulio, Luca Di Liberto, Marco Paglione, Igor Petenko, Mara Russo, Angela Marinoni, Gianpietro Casasanta, Sara Valentini, Vera Bernardoni, Federica Crova, Gianluigi Valli, Alice Corina Forello, Fabio Giardi, Silvia Nava, Giulia Pazzi, Paolo Prati, Virginia Vernocchi, Teresa La Torretta, Ettore Petralia, Milena Stracquadanio, Gabriele Zanini, Gloria Melzi, Emma Nozza, Martina Iulini, Donatella Caruso, Lucia Cioffi, Gabriele Imperato, Flavio Giavarini, Maria Battistoni, Francesca Di Renzo, Maria Agostina Frezzini, Cinzia Perrino, Maria Cristina Facchini

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: atmospheric aerosol; chemical composition; secondary aerosol; source apportionment; ultrafine particles; oxidative potential; exposure; toxicology; forecasting; micrometeorology

Online: 12 April 2022 (09:54:57 CEST)

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Working Paper ARTICLE

Effect of W on the Evolution of Precipitates in Ni-Co-Cr-W-Mo Super-Alloys

Hansheng Bao, Zhihua Gong, Zhengzong Chen, Gang Yang, Zhengdong Liu

Subject: Chemistry And Materials Science, Metals, Alloys And Metallurgy Keywords: nickel-based super-alloys; M6C; u phase; long time exposure; M12C

Online: 16 September 2019 (01:22:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201905.0204.v2

The Impact of Lake Water Quality on the Performance of Mature Artificial Recharge Ponds

Jing Li, Kristofer Hägg, Kenneth M. Persson

Subject: Engineering, Civil Engineering Keywords: groundwater; pre-treatment; contact filtration; infiltration ponds; nutrients removal; TP; Cyanobacteria; Cyanotoxin; microcystin-LR; eutrophic lakes; TOC

Online: 19 August 2019 (04:08:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0169.v1

Improved Multifactor Portfolio Optimization Method through Empirical Research in South Korea

DongJun Lee

Subject: Business, Economics And Management, Finance Keywords: asset allocation; risk factor; risk exposure; macro-factor

Online: 12 May 2022 (10:44:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202012.0484.v1

The Relationship between Nature Deprivation and Individual Wellbeing across Urban Gradients under COVID-19

Linda Powers Tomasso, Jie Yin, Jose Guillermo Cedeno Laurent, Jarvis T. Chen, Paul Catalano, John D. Spengler

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: nature exposure; nature deprivation; health disparities; wellbeing; built environment; urban health interventions

Online: 21 December 2020 (09:00:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202205.0234.v1

Physical Analysis of SARS-CoV-2 Routes: from Primary Production and Emissions to Exposures and COVID-19 Infection

Gjalt Huppes, Ruben Huele

Subject: Biology And Life Sciences, Biophysics Keywords: SARS-CoV-2; COVID-19; virions mass balance; spatial modelling of toxics concentrations; human exposure to airborne substances; Substance Flow Analysis (SFA); environmental routes of toxic viruses; primary production of SARS-2 virions

Online: 17 May 2022 (14:19:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0660.v1

Leveraging ChatGPT in Android App Development: A Case Study on Supporting Novice Developers in Creating Successful Apps

Mohamad Iyad Al-Khiami, Martin Jaeger

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Chat Generative Pre-Trained Transformer (ChatGPT); Artifcial Intelligence; Human-Computer Interaction; Human-AI Interaction Chatbot; App Development; Coding

Online: 11 July 2023 (09:30:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0114.v2

A Virtual Reality System for Improved Image-based Planning of Complex Cardiac Procedures

Shujie Deng, Gavin Wheeler, Nicolas Toussaint, Lindsay Munroe, Suryava Bhattacharya, Gina Sajith, Ei Lin, Eeshar Singh, Ka Yee Kelly Chu, Saleha Kabir, Kuberan Pushparajah, John M Simpson, Julia A Schnabel, Alberto Gomez

Subject: Medicine And Pharmacology, Other Keywords: virtual reality; pre-operative imaging; echocardiography

Online: 18 August 2021 (10:02:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0068.v1

Mesoscale Resolution Radar Data Assimilation Experiments with the Harmonie Model

Serguei Ivanov, Silas Michaelides, Igor Ruban

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Harmonie model; radar data assimilation; pre-processing; mesoscale precipitation patterns

Online: 3 August 2018 (12:56:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202103.0378.v1

Variation of Deoxynivalenol levels in Corn and Its Products Available in Retail Markets of Punjab, Pakistan and Estimation of Risk Assessment

Shahzad Zafar Iqbal, Ahmad Faizal Abdull Razis, Sunusi Usman, Nada Basheir Ali, Muhammad Rafique Asi

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: DON; corn; corn products; exposure; risk assessment

Online: 15 March 2021 (12:04:05 CET)

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Preprint ARTICLE | doi:10.20944/preprints202012.0820.v1

Inhibition of Adipogenesis in Mouse 3T3-L1 Pre-Adipocytes by an Extract from Sophora Japonica Fruit Acting via the AMP-Activated Protein Kinase Pathway

Cheol Park, Young-Kyung Lee, Chul Hwan Kim, Su Young Shin, Kyung-Min Choi, In-Jun Yang, Gi-Young Kim, Yung Hyun Choi, Jin-Woo Jeong

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Sophora japonica; Adipogenesis; AMPK; 3T3-L1 pre-adipocytes

Online: 31 December 2020 (14:24:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0140.v1

In-utero Ramadan Exposure and Child Nutrition

Hoi Chu, Srinivas Goli, Anu Rammohan

Subject: Business, Economics And Management, Economics Keywords: Child nutrition; Religion; Ramadan fasting; In-utero exposure

Online: 9 February 2022 (16:00:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202007.0746.v1

An Efficient Radio Frequency Interference Recognition Using End-to-end Transfer Learning

Sahar Ujan, Neda Navidi, Rene Jr Landry

Subject: Engineering, Electrical And Electronic Engineering Keywords: radio frequency interference detection; deep learning; transfer learning; pre-trained convolutional neural networks

Online: 31 July 2020 (12:06:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202109.0164.v2

A High Resolution Spatiotemporal Fine Particulate Matter Exposure Assessment Model for the Contiguous United States

Cole Brokamp

Subject: Environmental And Earth Sciences, Environmental Science Keywords: fine particulate matter; exposure assessment; machine learning; spatiotemporal; high resolution

Online: 17 December 2021 (14:46:46 CET)

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Currently available nationwide prediction models for fine particulate matter (PM_2.5) lack prediction confidence intervals and usually do not describe cross validated model performance at different spatiotemporal resolutions and extents. We used 41 different spatiotemporal predictors, including data on land use, meteorology, aerosol optical density, emissions, wildfires, population, traffic, and spatiotemporal indicators to train a machine learning model to predict daily averages of PM_2.5 concentrations at 0.75 sq km resolution across the contiguous United States from 2000 through 2020. We utilized a generalized random forest model that allowed us to generate asymptotically-valid prediction confidence intervals and took advantage of its usefulness as an ensemble learner to quickly and cheaply characterize leave-one-location-out CV model performance for different temporal resolutions and geographic regions. Using a variable importance metric, we selected 8 predictors that were able to accurately predict daily PM_2.5, with an overall leave-one-location-out cross validated median absolute error of 1.20 ug/m³, an R² of 0.84, and confidence interval coverage fraction of 95%. When considering aggregated temporal windows, the model achieved leave-one-location-out cross validated median absolute errors of 0.99, 0.76, 0.63, and 0.60 ug/m³ for weekly, monthly, annual, and all-time exposure assessments, respectively. We further describe the model’s cross validated performance at different geographic regions in the United States, finding that it performs worse in the Western half of the country where there are less monitors. The code and data used to create this model are publicly available and we have developed software packages to be used for exposure assessment. This accurate exposure assessment model will be useful for epidemiologists seeking to study the health effects of PM across the continental United States, while possibly considering exposure estimation accuracy and uncertainty specific to the the spatiotemporal resolution and extent of their study design and population.

Preprint REVIEW | doi:10.20944/preprints202306.1160.v1

Drinking Water Systems as a Cocktail of Emerging Organic Contaminants: Occurrence, Public Health Risks, and Research Needs

Jerikias Marumure, Tinoziva T Simbanegavi, Zakio Makuvara, Rangarirayi Karidzagundi, Richwell Alufasi, Marvelous Goredema, Claudious Gufe, Nhamo Chaukura, Willis Gwenzi

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: Human exposure; high-risk environments; human health hazards; personal care products; pharmaceuticals; per- and polyfluoroalkyl substances; risk factors

Online: 16 June 2023 (03:16:14 CEST)

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Emerging organic contaminants (EOCs) of anthropogenic origins are ubiquitous in environmental compartments, including aquatic systems. Thus, EOCs have attracted considerable research and public attention due to their potential human and ecological health risks. However, compared to other aquatic environments such as wastewater systems, comprehensive reviews focussing on the occurrence and human health risks of EOCs in drinking water systems are still lacking. Therefore, to address this knowledge gap, the current review posits that drinking water systems harbour a cocktail of toxic EOCs, which pose public health risks via multiple exposure routes. In the present review, global evidence is examined to track EOCs along the source-pathway-receptor-impact-mitigation (SPRIM) continuum. Evidence shows that, various groups of EOCs, including pharmaceuticals and personal care products, solvents, plasticizers, endocrine disrupting compounds, gasoline additives, per- and polyfluoroalkyl substances (PFAS), food colourants, artificial sweeteners, and musks and fragrances, have been detected in drinking water systems. The anthropogenic sources of EOCs detected in drinking water systems, including wastewater systems and industrial emissions, are summarized. Further, the behaviour and fate of EOCs in the drinking water systems, including removal processes are discussed. Once in drinking water systems, human exposure to EOCs may occur via ingestion of contaminated drinking water and cooked foods, and possibly dermal contact and inhalation. The high-risk environments, and risk factors and behaviours predisposing humans to EOC exposure are discussed. Evidence on the human health risks of the various EOCs and a critique of the data are presented. Notably, besides inferential data, quantitative epidemiological evidence directly relating the occurrence of EOCs in drinking water systems to specific adverse human health outcomes is still scarce. Lastly, future research directions, including the need for quantitative public health risk assessment, and the application of emerging detection tools are discussed.

Preprint ARTICLE | doi:10.20944/preprints202010.0641.v1

Aging-induced Changes in Sperm DNA Methylation are Modified by Low Dose of Perinatal Flame retardants

J.Richard Pilsner, Alex Shershebnev, Haotian Wu, Chelsea Marcho, Olga Dribnokhodova, Victoria Shtratnikova, Oleg Sergeyev, Alexander Suvorov

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: aging; paternal exposure; sperm; advanced paternal age; epigenetics; DNA methylation; RRBS, 2,2′,4,4′-tetrabromodiphenyl ether; PBDE; BDE-47; perinatal; environment

Online: 30 October 2020 (13:37:14 CET)

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Advanced paternal age at fertilization has been suggested to be a risk factor for neurodevelopmental, psychiatric and other disorders in offspring. One emerging hypothesis suggests that altered offspring phenotype is linked with age-related accumulation of epigenetic changes in the sperm of fathers. Given that paternal age is increasing in the developed world, understanding aging-related epigenetic changes in sperm is needed as well as environmental factors that modify such changes. In this study, we characterize age-dependent changes in sperm DNA methylation profiles between young pubertal (postnatal day (PNDs) 65) and mature (PND120) Wistar rats. We also analyze these changes in rats exposed perinatally to 0.2 mg/kg of ubiquitous environmental xenobiotic 2,2’,4,4’-tetrabromodiphenyl ether (BDE-47). Reduced representation bisulfite sequencing (RRBS) libraries were prepared from caudal epididymal sperm DNA and differentially methylated regions (DMRs; ≥ 10x coverage depth, ≥ 3 CpGs per cluster, ≥ 5% methylation change, q < 0.05) were identified via MethPipe package. In control animals, 5,319 age-dependent DMRs were identified, with 99.3% DMRs hypermethylated in mature animals compared to young pubertal rats. These age-related DMRs were enriched for functional categories essential for embryonic development, such as pattern specification, forebrain and sensory organ development, Hippo and Wnt pathways. Age-related changes in sncRNA, reported in different study, target similar list of genes and biological categories.In BDE-47 exposed rats, sperm DNA methylation was higher in young pubertal and lower in mature animals when compared to controls, which resulted in a significant attenuation in the number of age-dependent DMRs (N = 189) identified in the exposed group. In conclusion, our results indicate that the natural aging process has profound effects on sperm methylation levels and this effect may be modified by environmental exposures. Moreover, our results further support the role of epigenetic mechanisms as a likely link betwen paternal age and offspring health and development.

Preprint ARTICLE | doi:10.20944/preprints202102.0577.v1

Atherosclerotic Plaque Fissuration and Clinical Outcomes in Pre-Diabetics vs. Normoglycemics Patients Affected by Asymptomatic Significant Carotid Artery Stenosis at 2 Years of Follow-Up: Role of MIcRoRNAs Modulation. The ATIMIR Study

Celestino Sardu, Piero Modugno, Gaetano Castellano, Lucia Scisciola, Michelangela Barbieri, Lella Petrella, Mara Fanelli, Gabriella Macchia, Eugenio Caradonna, Massimo Massetti, Giuseppe Paolisso, Raffaele Marfella

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: carotid atherosclerosis; pre-diabetes mellitus; microRNAs; inflammation; metformin therapy

Online: 25 February 2021 (11:43:02 CET)

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BACKGROUND AND PURPOSE—Atherosclerotic plaque instability and rupture in patients with asymptomatic carotid artery stenosis (ACAS) is a leading cause of major adverse cardiac events (MACE). This could be mainly evidenced in patients with pre-diabetes. Indeed, the altered glucose homeostasis and insulin resistance could cause over-inflammation of atherosclerotic plaque, favoring its conversion to unstable phenotype with rupture and MACE. Notably, the metformin therapy reducing the metabolic distress and the inflammatory burden, could lead to reduction of MACE in ACAS patients with pre-diabetes. In this setting, microRNAs (miRs) could be used as molecular biomarkers of atherosclerosis progression, plaque rupture and worse prognosis in normoglycemics (NG) vs. pre-diabetics metformin users (PDMU) vs. pre-diabetics non metformin users (PDNMU). However, the aim of our study was to investigate a wide miRNA panel in peripheral blood exosomes from patients with ACAS divided in NG vs. PDMU vs. PDNMU, and to associate the circulating miRNA expression profiles with MACE at 2 years of follow-up after endarterectomy. METHODS—The study included 234 patients with ACAS divided in NG (n 125), PDNMU (n 73) and PDMU (n 36). The miRs’ expression profiles of circulating exosomes were determined at baseline and at 2 years of follow-up by Affymetrix microarrays from plasma samples of the patients from any study cohort. Then we collected and analyzed MACE at 2 years of follow-up in NG vs. PDMU vs. PDNMU. RESULTS—prediabetics vs. NG had over-inflammation (p<0.05) and over expressed miR 24 and miR 27 at baseline. At 2 years of follow-up PDNMU vs. NG, PDMU vs. NG and PDNMU vs. PDMU over-expressed inflammatory markers and miR 24, miR 27, miR 100, miR 126 and miR 133 (p<0.05). Finally, at follow-up end we observed a significant difference about MACE comparing PDNMU vs. NG (n 27 (36.9%) vs. n 8 (6.4%); p<0.05), PDNMU vs. PDMU (n 27 (36.9%) vs. n 6 (16.6%); p <0.05), and PDMU vs. NG (n 6 (16.6%) vs. n 8 (6.4%); p<0.05). Admission glucose values (HR 1.020, CI 95% [1.001-1.038], p 0.029), atheromatous carotid plaque (HR 5.373, CI 95% [1.251-11.079], p 0.024), and miR 24 (HR 3.842, CI 95% [1.768-19.222], p 0.011) predicted MACE at 2 years of follow-up. CONCLUSIONS—Specific circulating miRs could be over-expressed in pre-diabetics and specifically in PDNMU vs. PDMU after endarterectomy. MiR24, hyperglycemia and atheromatous plaque could predict MACE at 2 years of follow-up.

Preprint ARTICLE | doi:10.20944/preprints202201.0140.v1

Temporal and Spatial Evolution of Climate Comfort and Population Exposure in Guangdong Province in the Last Half Century

Ziqiang Ye, Song Song, Runfei Zhong

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: climate comfort index; temperature-humidity index; wind-effect index; clothing index; population exposure

Online: 11 January 2022 (13:04:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0337.v1

Pre-Intervention Effects of a Community-Based Intervention Targeting Alcohol Use (LEF); The Role of Participatory Research and Publicity

Ina Koning, Vincent G. van der Rijst, John B. F. de Wit, Charlotte De Kock

Subject: Social Sciences, Psychology Keywords: participatory research; pre-intervention; community-based intervention; alcohol use; adolescents

Online: 14 July 2021 (14:04:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201907.0333.v1

Litter Survival Differences between Divergently Selected Lines for Environmental Sensitivity in Rabbits

Ivan Agea, María-Luz García, Agustín Blasco, María-José Argente

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: correlated response; pre-weaning; survival; weight; welfare

Online: 29 July 2019 (09:40:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202109.0007.v1

Robot-Enhanced Language Learning for Children in Norwegian Day-Care Centers

Till Halbach, Trenton Schulz, Wolfgang Leister, Ivar Solheim

Subject: Computer Science And Mathematics, Robotics Keywords: Social robot; mobile app; e-learning; language education; kindergarden, pre-school

Online: 1 September 2021 (11:46:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0535.v1

Explosives Use in Decommissioning – Guide for Assessment of Risk (EDGAR): II Determination of Sound Exposure Levels for Open Water Blasts and Severance of Conductors and Piles from Below the Seabed

Alison Brand

Subject: Physical Sciences, Acoustics Keywords: Underwater noise modelling; decommissioning; explosives; sound exposure level; marine mammals; fish

Online: 23 July 2021 (10:41:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0288.v1

Effect of Fire Temperature and Exposure Time on High-strength Steel Bolts Microstructure and Residual Mechanical Properties

Paweł Artur Król, Marcin Wachowski

Subject: Engineering, Automotive Engineering Keywords: effect of temperature; exposure time; steel microstructure; residual mechanical properties; high-strength steel bolts; heat treatment of steel; phase transformation; fire; cooling method

Online: 13 May 2021 (12:53:32 CEST)

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The article presents results of research consisting in an attempt to assess the influence of temperature, heating time and cooling method on microstructure and residual strength properties of steel previously tempered during the production process. Simulated environmental conditions to which high-strength bolts, commonly used in steel construction, were subjected, were intended to reflect conditions of a natural fire that may occur in public facilities where the obligation to ensure safety of users and rescue teams is of key importance, also required by law. Furthermore, the tests carried out also comprised a simulated effect of a rescue and firefighting operation using shock, rapid cooling of some of the heated bolts. Samples cut out from the tested bolts, after they were properly prepared, were subjected to microstructural tests using light microscopy, scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), phase analysis with the use of an X-ray diffractometer (XRD) and quantitative analysis of the microstructure involving, inter alia, measuring the surface area of grains, their equivalent diameter and mean diameter. As a result of the tests, considerable microstructure changes were identified occurring in the bolt material as a result of exposing it to fire conditions, leading to a change in key, from the point of view of structural safety, mechanical properties. The results of the microstructure tests were compared with the results of previous strength tests, including hardness of the material after the heat treatment and the residual tensile strength of the material Rm. A conducted comparative analysis showed a significant effect of all such factors as the temperature level of the simulated fire, its duration and the fire-fighting method on the mechanical properties of bolts. Results obtained were provided with required comments and the concept of using the microstructure for the post-fire assessment of steel structures was referred to.

Preprint ARTICLE | doi:10.20944/preprints201810.0745.v1

$(q,\sigma,\tau)$-Differential Graded Algebras

Viktor Abramov, Olga Liivapuu, Abdenacer Makhlouf

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: q-differential graded algebra; (σ,τ)-differential graded algebra; generalized Clifford algebra; pre-cosimplicial complex

Online: 31 October 2018 (10:03:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0184.v1

Provider-Patient Interactions as Predictors of Lifestyle Behaviors Related to the Prevention and Management of Diabetes

Brenda Robles, Tony Kuo

Subject: Biology And Life Sciences, Food Science And Technology Keywords: type 2 diabetes; lifestyle behaviors; healthcare provider advice; provider-patient interactions; health care setting; brief lifestyle intervention exposure; diabetes prevention; diabetes management

Online: 15 February 2022 (09:20:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202106.0122.v1

Supporting Restoration Decisions through Integration of Tree-Ring and Modeling Data: Reconstructing Flow and Salinity in the San Francisco Estuary over the Past Millennium

Paul H Hutton, David M Meko, Sujoy B Roy

Subject: Environmental And Earth Sciences, Environmental Science Keywords: tree-ring; flow reconstruction; pre-development; estuarine salinity; salinity intrusion

Online: 4 June 2021 (08:11:27 CEST)

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This work presents updated reconstructions of watershed runoff to San Francisco Estuary from tree-ring data to AD 903, coupled with models relating runoff to freshwater flow to the estuary and salinity intrusion. We characterize pre-development freshwater flow and salinity conditions in the estuary over the past millennium and compare this characterization with contemporary conditions to better understand the magnitude and seasonality of changes over this time. This work shows that the instrumented flow record spans the range of runoff patterns over the past millennium (averaged over five, ten, twenty and one hundred years), and thus serves as a reasonable basis for planning-level evaluations of historical hydrologic conditions in the estuary. Over annual timescales we show that, although median freshwater flow to the estuary has not changed significantly, it has been more variable over the past century compared to pre-development flow conditions. We further show that the contemporary period is generally associated with greater spring salinity intrusion and lesser summer-fall salinity intrusion relative to the pre-development period. Thus, salinity intrusion in summer and fall months was a common occurrence under pre-development conditions and has been moderated in the contemporary period due to the operations of upstream reservoirs, which were designed to hold winter and spring runoff for release in summer and fall. This work also confirms a dramatic decadal-scale hydrologic shift in the watershed from very wet to very dry conditions during the late 19th and early 20th centuries; while not unprecedented, these shifts have been seen only a few times in the past millennium. This shift resulted in an increase in salinity intrusion in the first three decades of the 20th century, as documented through early records. Population growth and extensive watershed modification during this period exacerbated this underlying hydrologic shift. Putting this shift in the context of other anthropogenic drivers is important in understanding the historical response of the estuary and in setting salinity targets for estuarine restoration. By characterizing the long-term behavior of San Francisco Estuary, this work supports decision-making in the State of California related to flow and salinity management for restoration of the estuarine ecosystem.

Preprint TECHNICAL NOTE | doi:10.20944/preprints202203.0095.v1

An Algorithm for High-Resolution Satellite Imagery Pre-processing

Urmila Shrawankar, Chaitreya Shrawankar

Subject: Engineering, Control And Systems Engineering Keywords: pre-processing; image transformation; image enhancement; geometric correction; radiometric correction; Satellite Imagery

Online: 7 March 2022 (09:43:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202007.0211.v1

Phosphocholine Steroid Conjugates: Are these Compounds the Mammalian Cardiotonic Steroids?

Fred Chasalow

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: Ionotropin; Steroid phosphocholine esters; pre-eclampsia; endogenous ouabain; DLM; PTSD

Online: 10 July 2020 (09:55:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0041.v2

Reconstructing the 26 June 1917 Samoa Tsunami Disaster

Laura Sischka, Cyprien Bosserelle, Shaun Williams, Josephina Chan Ting, Ryan Paulik, Malcolm Whitworth, Lameko Talia, Paul Viskovic

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: coastal inundation; historical tsunami records; hazard exposure; impacts; BG-Flood; RiskScape

Online: 22 March 2022 (11:56:13 CET)

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The 26 June 1917 tsunamigenic earthquake in Samoa is considered the largest historical event on record to have impacted this region in terms of earthquake magnitude and intensity. Yet, very little is known about the scale and distribution of tsunami impacts compared with the recent 2009 event which originated about 150 km east along the subduction zone bend of the Northern Tonga Trench (NTT). In this study we set out to: 1) reconstruct the 1917 tsunami from source to inundation to understand its hazard risk characteristics in the Samoan islands of Savai’i and Upolu; and 2) assess the hazard implications of tsunamis sourced from different locations along the subduction zone bend of the NTT on present-day exposure of coastal assets relative to the 2009 tsunami benchmark. We use the BG-Flood numerical modelling suite to produce model outputs representing inundation extent and hazard depth intensities at spatially flexible grid resolution (10 m, 20 m and 40 m). These are validated using available tide gauge records in Apia harbour and limited observations of runup that were derived from historical records. We then combine the inundation model with available digital distributions of buildings in the RiskScape multi-hazard risk analysis software, to produce exposure metrics for understanding the likely impacts on present-day coastal asset and population distributions if a similar tsunami were to occur. Results of the tsunami modelling indicate variable modelled-to-observed consistency using available source models, wave and runup validation data. Discrepancies in recorded vs modelled wave arrival time at Apia of between 30—40 mins are observed, with modelled runup underestimated in southeast Upolu Island compared with the rest of the country where runup observations are available (e.g., Savai’i Island). These differences likely reflect complexities in the tsunami source mechanism which might not currently be represented in our modelling. Nevertheless, our results suggest that a larger proportion of people would be exposed in Savai’i island (71% of exposure total), compared with Upolu island if a characteristic 1917-type event were to occur. While this study provides the first detailed inundation model of the 1917 tsunami in the Samoan region, the observed discrepancies suggest that further investigation is required to constrain potential tsunami source complexities which might not be accounted for in this study. Notwithstanding these limitations, our findings help to reinforce an appreciation of the risk to the greater Samoan region faced by local tsunamis sourced at different locations along the subduction zone bend of the NTT.

Preprint REVIEW | doi:10.20944/preprints202205.0051.v1

A Reality We Have to Face in the Era of Tenofovir-Derived Pre-exposure Prophylaxis and Antiretroviral Therapy: A Paradigm Shift From the Reduction of HIV Risk to the Increased Risk of Cardiovascular Disease?

Jason Lew, Ilias Yee

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: Tenofovir; Pre-exposure prophylaxis; anti-retroviral therapy; cardiovascular disease; LGBT

Online: 5 May 2022 (16:11:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0260.v1

Calculation of Reasonable Tension Value for Longitudinal Connecting Reinforcement of CRTSII Slab Ballastless Track

Long Chen, Jin-jie Chen, Jian-xi Wang

Subject: Engineering, Civil Engineering Keywords: tension force; interface damage; CRTSII slab ballastless track; concrete crack; pre-stress

Online: 12 October 2018 (06:34:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0146.v1

Chronic Ambient Poisoning

Beth Alderman

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: ubiquitous exposure; diagnosis; research design; quality of health care; habitat injuries; discovery

Online: 11 May 2022 (05:40:27 CEST)

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Preprint REVIEW | doi:10.20944/preprints202110.0005.v1

Human Brown Adipose Tissue and Metabolic Health: Potential for Therapeutic Avenues

Rajan Singh, Albert Barrios, Golnaz Dirakvand, Shehla Pervin

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: Brown adipose tissue; beige adipose tissue; obesity; cold exposure; uncoupling protein-1, beta-adrenergic receptor; energy expenditure; adipose browning; micro-RNA

Online: 1 October 2021 (11:30:39 CEST)

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Obesity-associated metabolic abnormalities comprise of a cluster of conditions including dyslipidemia, insulin resistance, diabetes, and cardiovascular diseases that has affected more than 650 million people all over the globe. Obesity results from accumulation of white adipose tissues mainly due to the chronic imbalance of energy intake and energy expenditure. Variety of approaches to treat or prevent obesity, including lifestyle interventions, surgical weight loss procedures and pharmacological approaches to reduce energy intake and increase energy expenditure have failed to substantially decrease the prevalence of obesity. Brown adipose tissue (BAT), the primary source of thermogenesis in infants and small mammals may represent a promising therapeutic target to treat obesity by promoting energy expenditure through non-shivering thermogenesis mediated by mitochondrial uncoupling protein 1 (UCP1). Since the confirmation of functional BAT in adult humans by several groups, approximately a decade ago and its association with a favorable metabolic phenotype, intense interest on the significance of BAT in adult human physiology and metabolic health has emerged within the scientific community to explore its therapeutic potential for the treatment of obesity and metabolic diseases. Substantially decreased BAT activity in individuals with obesity indicates a role for BAT in setting of human obesity. On the other hand, BAT mass and its prevalence has been reported to correlate with lower body mass index (BMI), decreased age and glucose levels, leading to lower incidence of cardio metabolic diseases. Increased cold exposure in adult humans with undetectable BAT was associated with decreased body fat mass and increased insulin sensitivity. Deeper understanding of the role of BAT in human metabolic health and its inter-relationship with body fat distribution and deciphering proper strategies to increase energy expenditure by either increasing functional BAT mass, or inducing white adipose browning holds the promise for possible therapeutic avenues for the treatment of obesity and associated metabolic disorders.

Preprint ARTICLE | doi:10.20944/preprints201911.0001.v1

3D Printed Lab-on-a-Chip Diagnostic Systems - Developing a Safe-by-Design Manufacturing Approach

Panagiotis Karayannis, Fotini Petrakli, Anastasia Gkika, Elias Koumoulos

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: 3D printing; lab-on-a-chip; FFF; Safe-by-Design; exposure assessment

Online: 1 November 2019 (03:40:54 CET)

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Preprint REVIEW | doi:10.20944/preprints202010.0406.v1

Maternal Docosahexaenoic Acid Status During Pregnancy and Its Impact on Infant Neurodevelopment

Sanjay Basak, Rahul Mallick, Asim K Duttaroy

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: DHA; Brain; MFSD2a; SPM; Fetus; Placenta; infacnts; Neurogenesis; Pregnancy; Pre-term

Online: 20 October 2020 (08:37:41 CEST)

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Preprint REVIEW | doi:10.20944/preprints201808.0511.v1

Natural Background and Anthropogenic Arsenic Enrichment in Florida Soils, Surface Water, and Groundwater: A Review with a Discussion on Public Health Risk

Thomas M. Missimer, Christopher M. Teaf, William T. Beeson, Robert G. Maliva, John Woolschlager, Douglas J. Covert

Subject: Environmental And Earth Sciences, Environmental Science Keywords: arsenic; florida; soils; geologic units; groundwater; exposure; public health risk

Online: 30 August 2018 (05:13:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202009.0501.v1

Elevated Urinary Arsenic Level among Residents of an Arsenic-Endemic Area of Southern Thailand and its Related Factors: Three Decades after Mitigation Attempts

Udomsak Saengow, Surasak Vijitpongjinda, Supabhorn Yimthiang, Apichai Wattanapisit, Sirilak Thaicharoen

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: human arsenic exposure; water source; risk factors; Thailand

Online: 21 September 2020 (11:32:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0086.v1

A Comprehensive Approach for Floodplain Mapping Through Identification of Hazard Using Publicly Available Data Sets Over Canada

Mohit Prakash Prakash Mohanty, Slobodan P. Simonovic

Subject: Engineering, Civil Engineering Keywords: Flood hazard; CaMa-Flood; Flood Map Viewer; Floodplain mapping; Flood risk; North American Regional Reanalysis; Property exposure

Online: 11 April 2022 (03:35:28 CEST)

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Flood events and their associated damages have escalated significantly in the last few decades. To add to the gruesome situation, many reports and studies warn that flood risk would aggravate significantly in future periods due to significant alterations in the climate patterns and socio-economic dynamics. Floodplain mapping is looked upon as a viable option to tackle this global issue as it provides both quantitative and qualitative information on flood dynamics. Moreover, with the increasing availability of global data and enhancement in computational simulations, it has become easier to simlate flooding patterns at large scales. This study deter-mines the usability of publicly available datasets in capturing flood hazards over Canada. Run-off data set from the North American Regional Reanalysis (NARR), along with a few other rele-vant inputs are fed to CaMa-Flood, a robust global hydrodynamic model to generate flooding patterns for 1 in 100 and 1 in 200-yr return period events over Canada . The simulated maps are compared and validated with the existing maps of a few flood-prone regions in Canada, thereby establishing their performance over both regional and country-scale. Later, the simulated flood-plain maps are used in conjunction with property related information at 34 cities (within the top 100 populous cities in Canada) to determine the degree of exposure due to flooding in 1991, 2001, and 2011. The results indicate that around 80 percent of inundated spots belong to high and very-high hazard classes in a 200-yr event, which is roughly 4 percent more than simulated for 100-yr event. NARR derived floodplain maps perform very well while compared over the six flood-prone regions. While analyzing the exposure of properties to flooding, we notice an in-crease in the number during the last three decades, with the maximum rise observed in Toronto, followed by Montreal, and Edmonton. To disseminate the extensive flood-related information, a web-based public tool, Flood Map Viewer (http://www.floodmapviewer.com/) is developed. The development of the tool was motivated by the commitment of the Canadian government to provide $63 M over the next three years for the completion of flood maps for higher-risk areas. The study reaches out to demonstrate how publicly available datasets can be utilized with a lesser degree of uncertainty in representing flooding patterns over large regions. The flood re-lated information derived from the study can be used along with vulnerability for quantifying flood risk, which will help in developing appropriate pathways for resilience building for long-term sustainable benefits.

Preprint ARTICLE | doi:10.20944/preprints202010.0153.v1

Study on the Compressive Behaviour of Sustainable Cement-Based Composites Under 1-Hour Direct Flame Exposure

Ajitanshu Vedrtnam, Chiara Bedon, Gonzalo Barluenga

Subject: Engineering, Automotive Engineering Keywords: Concrete; Cement-Based Composites (CBCs); compressive strength; fire exposure; thermal boundaries; Finite Element (FE) numerical modelling; empirical formulations.

Online: 7 October 2020 (09:27:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0339.v1

Aging Induces Profound Changes in sncRNA in Rat Sperm and these Changes are Modified by Perinatal Exposure to Environmental Flame Retardant

Alexander Suvorov, Vladimir Naumov, Victoria Shtratnikova, J.Richard Pilsner, Anna Zheludkevich, Evgeny Gerasimov, Maria Logacheva, Oleg Sergeyev

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: aging; paternal exposure; sperm; semen; epigenetics; sncRNA; piRNA; miRNA; 2,2′,4,4′-tetrabromodiphenyl ether; PBDE; BDE-47; perinatal; environment.

Online: 16 October 2020 (08:10:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0017.v3

Effectiveness of High-Intensity Interval Training and Continuous Moderate-Intensity Training on Blood Pressure in Physically Inactive Pre-Hypertensive Young Adults

Anil T. John, Moniruddin Chowdhury, Rabiul Islam, Imtiyaz Ali Mir, Md Zobaer Hasan, Chao Yi Chong, Syeda Humayra, Yukihito Higashi

Subject: Medicine And Pharmacology, Internal Medicine Keywords: High-intensity interval training; Continuous aerobic training; Systolic blood pressure; Diastolic blood pressure; Pre-hypertension

Online: 13 July 2022 (09:21:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0215.v1

Deriving the Arrhenius Equation and the Pre-Exponential Factor

Rupeng Dou

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: Arrhenius Equation; Boltzmann distribution; Pre-exponential factor; Collision theory

Online: 11 April 2023 (08:51:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0334.v1

Environmental Exposures and Phenotype of Non-smoking COPD

Sameer Arbat, Ashok Arbat, Bharat Agrawal, Parimal Deshpande, Irfan Rahman, Swapnil Bakamwar, Prajakta Borkar

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: non-smoking COPD; phenotypes; air pollution; biomass; occupational exposure

Online: 24 June 2022 (08:18:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202012.0552.v1

In Vitro Impact Preliminary Assessment of Airborne Particulate From Metalworking and Woodworking Industries

Ilona Pavlovska, Anna Ramata-Stunda, Žanna Martinsone, Martins Boroduskis, Liene Patetko, Inese Martinsone, Anita Seile, Ivars Vanadziņš

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Nanoparticles; metallic compounds; airborne particulate; occupational environment; in vitro exposure; alternative testing strategies; EpiAirway™; 3D tissue models; respiratory epithelial tissues

Online: 22 December 2020 (10:40:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202007.0680.v1

Effects of Air Pollution on the Risk of Low Birth Weight in a Cold Climate

Hamudat Balogun, Aino Rantala, Harri Antikainen, Nazeeba Siddika, A.Kofi Amegah, Niilo Ryti, Jaakko Kukkonen, Mikhail Sofiev, Maritta S. Jaakkola, Jouni Jaakkola

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: Air pollution; low birth weight; prenatal exposure; joint effects; cold climate

Online: 28 July 2020 (10:43:42 CEST)

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Preprint REVIEW | doi:10.20944/preprints202003.0254.v1

Inflammatory Responses during Tumour Initiation: From Zebrafish Transgenic Models of Cancer to Evidence from Mouse and Man

Abigail Elliot, Henna Myllymäki, Yi Feng

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: zebrafish; inflammation; tumour initiation; macrophage; neutrophil; cancer; pre-neoplastic; live imaging; tumourigenesis; tumour model

Online: 16 March 2020 (01:31:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202010.0425.v1

Remote Sensing Based Methodology for the Quick Update of Population Exposed to Natural Hazards

Giorgio Boni, Silvia De Angeli, Angela Celeste Taramasso, Giorgio Roth

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: exposure; urban development; nightlights intensity; population distribution; natural hazards; remote sensing

Online: 21 October 2020 (09:35:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202110.0031.v2

User-Centred Design of a Final Results Report for Participants in Multi-Sensor Personal Air Pollution Exposure Monitoring Campaigns

Johanna Amalia Robinson, Rok Novak, Tjaša Kanduč, Thomas Maggos, Demetra Pardali, Asimina Stamatelopoulou, Dikaia Saraga, Danielle Vienneau, Benjamin Flückiger, Ondřej Mikeš, Céline Degrendele, Ondřej Sáňka, Saul García Dos Santos-Alves, Jaideep Visave, Alberto Gotti, Marco Giovanni Persico, Dimitris Chapizanis, Ioannis Petridis, Spyros Karakitsios, Dimosthenis A. Sarigiannis, David Kocman

Subject: Environmental And Earth Sciences, Environmental Science Keywords: user centred design; air pollution exposure campaign; report to participants; communication; focus group; design thinking

Online: 4 November 2021 (15:18:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints201811.0006.v1

Evaluation of Prestress Loss Distribution during Pre-Tensioning and Post-Tensioning Using Long-Gauge Fiber Bragg Grating Sensors

Sheng Shen, Yao Wang, Sheng-Lan Ma, Di Huang, Zhi-hong Wu, Xiao Guo

Subject: Engineering, Civil Engineering Keywords: prestress monitoring; prestress loss; pre-tensioning; post-tensioning; long-gauge fiber Bragg grating; strain distribution

Online: 2 November 2018 (02:19:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202207.0038.v1

Progeria and Aging - Omics Based Comparative Analysis

Aylin Caliskan, Samantha Agnetz Wilhelmine Crouch, Sara Giddins, Thomas Dandekar, Seema Dangwal

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: progeria; aging; omics; RNA Sequencing; bioinformatics; sun exposure; HGPS; IGFBP2; ACKR4; WNT

Online: 4 July 2022 (08:10:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1014.v1

A Comparative Study of Large Language Models in Explaining Intrinsically Disordered Proteins

David Taylor Gonzalez, Mak Djulbegovic, Colin Kim, Michael Antonietti, Gustavo Rosa Gameiro, Vladimir N. Uversky

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Artificial Intelligence; Generative Pre-Trained Transformers (GPT); Intrinsically Disordered Proteins (IDPs); Large Language Models (LLMs); Pathways Language Model 2 (PaLM 2)

Online: 14 August 2023 (09:44:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0153.v1

Is There a Need for Alcohol Policy to Mitigate Metal Contamination in Unrecorded Fruit Spirits?

Dirk W. Lachenmeier

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: unrecorded alcohol; home-produced fruit spirits; metals; lead; cadmium; ethanol; health risk; risk assessment; margin of exposure

Online: 10 March 2020 (02:44:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202011.0009.v1

Pathological Test Type and Chemical Detection Using Deep Neural Networks: A Case Study Using ELISA and LFA Assays

Marzia Hoque Tania, M. Shamim Kaiser, Kamal J. Abu-Hassan, M A Hossain

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Computer Vision; Machine Learning; Colourimetric Test; Pre-trained Model; Point-of-Care System; Diagnosis

Online: 2 November 2020 (09:56:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202008.0172.v2

Vegetation Survival in Green Roofs without Irrigation

Anita Raimondi, Mariana Marchioni, Umberto Sanfilippo, Gianfranco Becciu

Subject: Engineering, Automotive Engineering Keywords: Sustainable Urban Drainage Systems; green roofs; analytical probabilistic approach; pre-filling volume; vegetation survival

Online: 7 December 2020 (08:07:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0361.v2

Brief Exposure to Infants Activates Social and Intergroup Vigilance

Bobby Cheon, Gianluca Esposito

Subject: Social Sciences, Psychology Keywords: parental care system; intergroup bias; infant exposure; social vigilance

Online: 27 March 2020 (03:51:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints201810.0290.v1

Application of Numerical Tools to Investigate a Leaky Aquitard beneath Urban Well Fields

Farhad Jazaei, Brian Waldron, Scott Schoefernacker, Daniel Larsen

Subject: Engineering, Civil Engineering Keywords: groundwater model; well field; pre-field investigation; aquitard breach

Online: 15 October 2018 (08:30:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0026.v1

An Exploration of A Reflective Evaluation Tool for the Teaching Competency of Pre-Service Physical Education Teachers in Korea

Kim Chul-Min, Kwak Eun-Chang

Subject: Social Sciences, Education Keywords: reflective evaluation tool; pre-service teacher education; teaching competency; pre-service phys-ical education teacher; Delphi survey

Online: 2 June 2022 (04:44:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202008.0339.v1

Reconstructed f(R) Gravity and Its Csmological Consequences in Chameleon Scalar Field with A Scale Factor Describing The Pre-Bounce Ekpyrotic Contraction

Soumyodipta Karmakar, Kairat Myrzakulov, Surajit Chattopadhyay, Ratbay Myrzakulov

Subject: Physical Sciences, Particle And Field Physics Keywords: pre-bounce ekpyrotic contraction; f(R) gravity; reconstruction

Online: 15 August 2020 (06:15:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0359.v1

Biomolecular Fluorescence Complementation Profiling and Artificial Intelligence Structure Prediction of the Kaposi’s Sarcoma-associated Herpesvirus ORF18 and ORF30 Interaction

Yoshiko Maeda, Tadashi Watanabe, Taisuke Izumi, Kazushi Kuriyama, Shinji Ohno, Masahiro Fujimuro

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: Kaposi’s sarcoma-associated virus (KSHV); Viral pre-initiation complex (vPIC); Bimolecular fluorescence complementation (BiFC); Artificial intelligence (AI) structure prediction; AlphaFold2

Online: 27 June 2022 (10:15:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0166.v1

The Influence of Parental Environmental Exposure and Nutrient Restriction on the Early Life of Offspring Growth in Gambia

Ousman Bajinka, Sang Mendy, Binta JJ Jallow, Jarry Jallow, Amadou Barrow, Sulayman Barrow, Ousman Bah, Saikou Camara, Modou Lamin Colley, Sankung Nyabally, Amie Joof, Yurong Tan

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Epigenetics; Toxicant exposure; Maternal stress; Parental smoking; Offspring health

Online: 9 August 2022 (03:27:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0178.v3

The Meta-Dynamic Nature of Consciousness

John Barnden

Subject: Physical Sciences, Thermodynamics Keywords: consciousness; meta-causation; pre-reflective self-consciousness; physicalism; causal productivity; dynamism; laws of nature; laws of physics; temporal non-locality

Online: 27 August 2020 (08:27:28 CEST)

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Working Paper ARTICLE

Protective Effects of GIC and S-PRG Filler Restoratives on Demineralization of Bovine Enamel in Lactic Acid Solution

Naoyuki Kaga, Futami Nagano-Takebe, Takashi Nezu, Takashi Matsuura, Kazuhiko Endo, Masayuki Kaga

Subject: Chemistry And Materials Science, Biomaterials Keywords: pH neutralization; ion release; enamel demineralization; glass ionomer cement; surface pre-reacted glass ionomer filler

Online: 5 May 2020 (04:22:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0766.v1

ChatGPT for Digital Forensic Investigation: The Good, The Bad, and The Unknown

Mark Scanlon, Frank Breitinger, Christopher Hargreaves, Jan-Niclas Hilgert, John Sheppard

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: ChatGPT; Digital Forensics; Artificial Intelligence; Generative Pre-trained Transformers (GPT); Large Language Models (LLM)

Online: 12 July 2023 (09:09:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0119.v1

Follow-up of Elevated Blood Lead Levels and Sources in a Cohort of Children in Benin

Shukrullah Ahmadi, Barbara Le Bot, Roméo Zoumenou, Séverine Durand, Nadine Fiévet, Pierre Ayotte, Achille Massougbodji, Jules Alao, Michel Cot, Philippe Glorennec, Florence Bodeau-livinec

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Lead poisoning; environmental health; toxic metals; sub-Saharan Africa; environmental exposure

Online: 6 October 2020 (10:55:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0359.v1

Characterization of Potential Threats from Cyanobacterial Toxins in Lake Victoria Embayments and During Water Treatment

Mark Olokotum, Jean-François Humbert, Catherine Quiblier, William Okello, Ronald Semyalo, Marc Troussellier, Benjamin Marie, Kathrin Baumann, Rainer Kurmayer, Cécile Bernard

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Drinking water; rapid sand filtration; Recreational areas; Exposure; Microcystis and Dolichospermum; Microcystins

Online: 25 July 2022 (08:16:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202111.0269.v1

Lead Solubility in the Kırklareli Stream, Turkey

Sultan Kıymaz, Hacer Gülocak, William F. Bleam

Subject: Environmental And Earth Sciences, Environmental Science Keywords: groundwater chemistry; surface water chemistry; lead toxicity; lead exposure; solubility diagrams; solubility modeling

Online: 15 November 2021 (15:00:46 CET)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202309.0111.v1

Conceptualization and Construction of a Low-Cost and Self-Made Device for Monitoring of Particulate Matter: A Step-by-Step Guide

Giacomo Fanti, Francesca Borghi, Emanuele Cauda, Cody Wolfe, justin Patts, Carlo Dossi, Andrea Cattaneo, Andrea Spinazzè, Domenico Cavallo

Subject: Environmental And Earth Sciences, Pollution Keywords: miniaturized monitors; Arduino; air quality; air pollution; exposure assessment; low-cost monitor

Online: 3 September 2023 (13:52:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0262.v1

How Is the Exposure of a Sarcoma Surgeon Defined?

Carlo Theus-Steinmann, Georg Schelling, Philip Heesen, Stefan Breitenstein, Mario F. Scaglioni, Bruno Fuchs

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: sarcoma; multidisciplinary team / MDT; sarcoma surgery; orthopedic oncology; real-world data registry; exposure; experience

Online: 18 July 2022 (10:18:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.2161.v1

A Proof of Collatz Conjecture

HUANG Qingxue

Subject: Computer Science And Mathematics, Mathematics Keywords: pre odd number; post odd number; classification of odd numbers; sequence classification of odd numbers,1-1 mapping between odd numbers and odd number sequences

Online: 31 May 2023 (03:10:05 CEST)

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Preprint REVIEW | doi:10.20944/preprints202304.0349.v1

Effect of Prenatal Ketamine Exposure: A Focused Literature Review

Alexa Simonetti, Alicia Trimble, Hattie Shrock, Revathi Gudi, Varsha Murthy

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: N-methyl-D-aspartate (NMDA) receptors; prenatal exposure; neurotoxic

Online: 14 April 2023 (04:29:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0365.v1

Population-Based Disparities in U.S. Urban Heat Exposure from 2003 – 2018

Daniel P. Patrick Johnson

Subject: Environmental And Earth Sciences, Environmental Science Keywords: surface urban heat island; racial disparity; thermal exposure; environmental justice; social justice; climate justice; Bayesian spatial temporal modelling

Online: 19 August 2022 (13:34:09 CEST)

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Previous studies have shown, in the United States (U.S.), that non-White communities are exposed to significantly higher temperatures in urban environments than complementary White populations. Studies highlighting this disparity have usually been cross-sectional and are therefore “snapshots” in time. Using surface urban heat island (SUHI) intensity data, U.S. Census 2020 population counts, and a measure of residential segregation, this study performs a comparative analysis between census tracts identified as prevalent for White, Black, Hispanic and Asian populations and their thermal exposure from 2003 – 2018. The analysis concentrates on the top 200 most populous U.S. cities. SUHI intensity is shown to be increasing through time for all examined tracts. However, the increase is only statistically significant for White and Black prevalent zones. There is a 1.25K to ~2.00K higher degree of thermal exposure on average for non-White relative to White prevalent areas. When examined on an inter-city basis, White and Black prevalent tracts had the largest disparity, as measured by SUHI intensity, in New Orleans, LA, USA by < 6.00K. Hispanic (>7.00K) and Asian (<6.75K) prevalent tracts were greatest in intensity in San Jose, CA, USA. To further explore temporal patterns, two models were developed using a Bayesian hierarchical spatial temporal framework. One models the effect of varying the percentages of each population group relative to SUHI intensity within all examined tracts. Increases in percentages of Black, Hispanic, and Asian populations contributed to statistically significant increases in SUHI intensity. White increases in population percentage lowered SUHI temperature intensity. Throughout all modeled tracts, there is a statistically significant 0.01K per year average increase in SUHI intensity. A second model tests the effect of residential segregation on thermal inequity across all examined cities. Residential segregation, indeed, has a statistically significant positive association with SUHI intensity from this portion of the analysis. Similarly, there is a statistically significant 0.01K increase in average SUHI intensity per year for all cities. Results from this study can be used to guide and prioritize intervention strategies and furthers urgency related to social, climatic, and environmental justice concerns.

Preprint ARTICLE | doi:10.20944/preprints202208.0256.v1

Lead Exposure in Infancy and Subsequent Childhood Growth

Shukrullah Ahmadi, Jérémie Botton, Roméo Zoumenou, Pierre Ayotte, Nadine Fievet, Achille Massougbodji, Maroufou Jules Alao, Michel Cot, Philippe Glorennec, Florence Bodeau-Livinec

Subject: Biology And Life Sciences, Toxicology Keywords: Heavy metals; lead exposure; growth outcomes; cohort study

Online: 15 August 2022 (11:22:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.1176.v1

Ex Vivo Drug Testing of Patient-Derived Lung Organoids to Predict Treatment Responses for Personalized Medicine

Chia-Nung Hung, Maddison Williams, Ryan Williams, Meizhen Chen, Samaneh Kamali, Vaishnavi Sambandam, Cheryl Hsiang-Ling Chiu, Pawel Osmulski, Maria Gaczynska, Daniel DeArmond, Christine Gaspard, Maria Macini, Lina Song, Lingtao Jin, Paolo Schiavini, Chun-Liang Chen, Josephine Taverna

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: lung cancer; organoid; drug screening; high throughput; translational; pre-clinical; clinical; tumor microenvironment; personalized medicine

Online: 16 June 2023 (08:42:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1205.v1

Microplastics, Additives, and Plasticizers in Freshwater Bivalves: Preliminary Research of Biomonitoring

Giulia Cesarini, Fabiana Corami, Beatrice Rosso, Massimiliano Scalici

Subject: Biology And Life Sciences, Aquatic Science Keywords: freshwaters; environmental exposure; gills; gastrointestinal tracts; biological uptake; nylon; rayon

Online: 19 June 2023 (09:47:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0635.v1

Potato Peels to Bioethanol: Evaluation of Different Pre-treatment Strategies for Low-Cost Saccharification Using In-house Produced Multi-Enzyme System

Sanjeev Kumar Soni, Binny Sharma, Apurav Sharma, Bishakha Thakur, Raman Soni

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Potato peels; Pre-treatment; Multiple enzyme system; Enzymatic saccharification; Fermentation; Bioethanol

Online: 9 May 2023 (10:25:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0348.v1

Vulnerability Assessment to Flood Hazards of Households in Flood-Prone Areas of Kasese District, Western Uganda

Yayiru Tibara, Hannington Wasswa, Henry Musoke Semakula

Subject: Environmental And Earth Sciences, Environmental Science Keywords: floods; vulnerability; exposure; adaptive capacity; Uganda

Online: 24 October 2022 (05:08:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1083.v1

LogBD: A Log Anomaly Detection Method Based on Pre-trained Models and Domain Adaptation

Le Deng, Shuxian Liu, Huan Xu, Wei Wang

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: log anomaly detection; pre-trained models; domain adaptation

Online: 16 May 2023 (04:49:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1136.v1

Observance of Standard Precautions for Infection Prevention in the COVID-19 Era: A Cross Sectional Study in Six District Hospitals in Yaounde, Cameroon

Fabrice Zobel Lekeumo Cheuyem, Emilia Enjema Lyonga, Jonathan Hangi Ndungo, François–Xavier Mbopi–Keou, Innocent Takougang

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: standard precautions; occupational exposure; personal protective equipment; COVID-19; vaccination; Yaounde hospital; cameroon

Online: 18 July 2023 (03:29:50 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202301.0067.v1

Quick Report of the ML=3.3 on 1 January 2023 Guidonia (Rome, Italy) Earthquake: Evidence of a Seismic Acceleration

Dedalo Marchetti, Kaiguang Zhu, Laura Marchetti, Yiqun Zhang, Wenqi Chen, Yuqi Cheng, Mengxuan Fan, Siyu Wang, Ting Wang, Jiami Wen, Donghua Zhang, Hanshuo Zhang

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: seismic acceleration; Guidonia; earthquake; Benioff cumulative stress; Swarm; pre-earthquake processes

Online: 4 January 2023 (06:08:38 CET)

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Preprint REVIEW | doi:10.20944/preprints202306.2231.v1

Attention Deficit-Hyperactive Disorder (ADHD): From Abnormal Behavior to Impairment in Synaptic Plasticity

Gonzalo Ugarte, Ricardo Piña, Darwin Contreras, Felipe Godoy, David Rubio, Carlos Rozas, Marc Zeise, Bernardo Morales

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: neurodevelopmental disorders; hippocampus; long-term potentiation; dendritic spines; prenatal nicotine exposure model

Online: 30 June 2023 (12:16:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2171.v1

Pre-exposure prophylaxis for COVID-19 with Tix-agevimab/Cilgavimab in kidney transplant recipients in the Kraken variant (XBB.1.5) era: A Single-center Experience

Biagio Pinchera, Rosa Carrano, Fabrizio Salemi, Amerigo Piccione, Elisa Schettino, Paolo Romano, Emilia Trucillo, Alessia D'Agostino, Marina Sarno, Emanuela Zappulo, Ivan Gentile

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Tixagevimab/Cilgavimab, kidney transplantation, SARS-CoV-2, COVID-19, Kraken variant, XBB.1.5, pre-exposure prophylaxis, immunosuppressed patients

Online: 2 October 2023 (11:22:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202301.0550.v1

Assessing Completeness of OpenStreetMap Building Footprints Using a Gamification Approach in MapSwipe

Tahira Ullah, Sven Lautenbach, Benjamin Herfort, Danijel Schorlemmer

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: OpenStreetMap; MapSwipe; data completeness; disaster management; exposure, Volunteered Geographic Information; data quality

Online: 30 January 2023 (09:29:16 CET)

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Preprint SHORT NOTE | doi:10.20944/preprints202303.0553.v2

The A(H5N1) Avian Influenza Virus at the Domestic Animal-Wildlife-Human Interface: Issues of Concern

Giovanni Di Guardo

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: A(H5N1) avian influenza virus; Influenza viruses; Virus host range; Zoonotic risk, Human exposure risk; Viral infection; Epidemiology

Online: 4 April 2023 (14:22:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202211.0310.v2

The Effect of Two Parallel Crack Inclination Angles on the Stability of Concrete Members under Dynamic Loading

Ahmad Moradpour, Mojtaba Hosseini, Hamidreza Babaali

Subject: Engineering, Civil Engineering Keywords: Dynamic loadings; Inclination angles; Numerical simulation; Pre-cracked concrete

Online: 21 November 2022 (09:06:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202301.0136.v1

Exploring Skills in Observing Teaching Competency through Video Evaluation of Class Demonstrations by Pre-service Physical Education Teachers

Chul-min Kim, Min-jun Kim, Hyun-su Youn, Joo-Hyug Jung

Subject: Social Sciences, Education Keywords: pre-service teacher education; teacher evaluation; pre-service physical education teacher; class demonstration; teaching behavior analysis

Online: 9 January 2023 (03:09:08 CET)

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Preprint REVIEW | doi:10.20944/preprints202401.0008.v1

Human Pesticide Exposure in Bolivia: A Scoping Review of Current Knowledge, Future Challenges and Research Needs

Jessika Ximena Barrón Cuenca, Kristian Dreij, Noemi Sandra Tirado Bustillos

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Pesticides exposure; health effects, Bolivia, farmers, Bolivian regulations

Online: 3 January 2024 (03:48:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.0400.v1

Harnessing the Power of Physiologically Based Pharmacokinetic Modeling to Explore Potential Discordance between in vitro Dissolution, Local Gut vs Systemic Bioequivalence in Health and Disease: The Case of Budesonide in Crohn’s Disease

Chunyan Han, Tiancheng Sun, Sirikalyan Chirumamilla, Frederic Bois, Mandy Xu, Amin Rostami-Hodjegan

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: local bioequivalence; gut wall exposure; PBPK; Crohn’s disease; budesonide

Online: 4 August 2023 (11:34:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0683.v2

Perception Of Pre-Marital Sex, Courtship among Osun State University Undergraduates, Osogbo, Osun State

Abdulazeez A. Olayiwola, Adeyemi O. Omoge, Abayomi Olarinmoye, Grace Benzard, Halima U. Yahaya, Odunayo G. Aborisade, Jennifer Osolase

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Pre-Marital Sex; courtship; influences; university; undergraduates

Online: 17 October 2023 (03:38:54 CEST)

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BACKGROUND: Pre-marital sex is a sexual interest practiced by people who are yet to get married and has ended up being accepted specifically in western countries. Sex before marriage is sexual behavior engaged in by single people. In the past, having sex before getting married is seen as a moral dilemma that many cultures forbade and that many people regarded to be sin in many religions, although it has gained wider acceptance across the board. OBJECTIVES: This study was carried out to determine the perception, practices, and factors associated with pre-marital sex, courtship, and its influences among Osun State University Undergraduates, Osogbo, Osun State. METHODOLOGY: The study was a descriptive study, and respondents were selected using multi-stage sampling technique. Students of Osun State University, Osogbo main campus form the population of the study and its sample size was calculated using Leslie Kish’s formula. A total of 387 responses were validated from the survey. The instrument for data collection was a self-administered semi-structured questionnaire consisting of four sections. The data obtained were collated, examined for completion, coded, imputed, and analyzed using SPSS v21. RESULTS: The mean age of the respondents was between 19.19±2.17, and the majority were between 18 – 24 years. About 52% of the respondents show a positive perception of premarital sex and courtship. Also, in the practice of courtship majority (88.3%) of the respondents think those that go around together are courting and from the responses obtained and analyzed from the factors leading to pre-marital sex, the findings revealed that peer pressure (90.4%), Internet (86.7%), pornography (83.9%) and drugs (82.9%) are the leading factors which contribute to pre-marital sex among undergraduates. CONCLUSION: The study hereby recommends that Parents should as a matter of responsibility monitor and pays regular visits to their children in the universities and provide them with materials that will make them stay comfortable for them not to fall victim to peer pressure.Pre-marital sex is a practice that should be avoided by undergraduate students, though most students consider courtship as a normal practice, it is still used as a normal factor that leads them to practice pre-marital sex.

Preprint ARTICLE | doi:10.20944/preprints202310.1557.v1

Identification of Pre-emptive Biosecurity Zone Areas for Highly Pathogenic Avian Influenza Based on Machine Learning-Driven Risk Analysis

Kwang Myung Jeon, Jinwoo Jung, Chang-Min Lee, Dae Sung Yoo

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Highly Pathogenic Avian Influenza (HPAI); Biosecurity Zones; Machine Learning; Risk Analysis; Pre-emptive depopulation

Online: 24 October 2023 (16:46:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0306.v1

Emotional Intelligence and Empathy in Pre-primary Teachers: A Pilot Test

Paula Domínguez-Marquez, Bartolomé Pizà-Mir

Subject: Social Sciences, Education Keywords: Empathy; Emotional Education; Emotional Intelligence; Emotional competences; pre-primary Education

Online: 16 December 2022 (14:05:19 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.1150.v1

Noradrenergic Transmission in the Basolateral Amygdala Mediates the Effects of Predatory Odor Exposure on Hippocampal Plasticity – a New Concept for Studying the Emotional Modulation of Memory Consolidation

Bogomil Peshev, Petya Ivanova, Desislava Krushovlieva, Lidia Kortenska, Dimitrinka Atanasova, Nikolai Lazarov, and Jana Tchekalarova

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: basolateral amygdala; noradrenaline; memory consolidation; object location task; predator odor exposure; pCREB; Arc

Online: 19 March 2024 (12:48:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202307.0017.v1

Building Climate Resilience for Sustainable Livelihoods: Addressing Challenges Faced by Blue Collared Migrants in Adapting to New Climates

Anurupa Bhattacharjee, Princy Thomas

Subject: Social Sciences, Other Keywords: blue-collared migrants; climate resilience; adaptation; new climates; poverty alleviation; employment challenges; sustainable livelihoods; climate shocks; cultural nuances; social dynamic; support measures; pre-departure training; retraining opportunities; poverty reduction; inclusive development

Online: 3 July 2023 (08:27:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202211.0040.v1

Towards Outdoor Electromagnetic Field Exposure Mapping Generation Using Conditional GANs

Mohammed Mallik, Angesom Ataklity Tesfay, Benjamin Allaert, Esteban Egea Lopez, Jose-Maria Molina-Garcia Pardo, Redha Kassi, Joe Wiart, Davy P. Gaillot, Laurent Clavier

Subject: Engineering, Telecommunications Keywords: EMF exposure; conditional generative adversarial network; optimization

Online: 2 November 2022 (03:43:14 CET)

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Preprint REVIEW | doi:10.20944/preprints202309.0288.v1

Bridging the Gaps between Microplastics and Human Health

Stephanie Damaj, Farah Trad, Dennis Goevert, Jeff Wilkesman

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: Exposure routes; Human breast milk; Human placenta; Microplastics; Nanoplastics

Online: 6 September 2023 (03:19:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1634.v1

Potential Effects of Permanent Daylight Savings Time on Daylight Exposure and Risk During Commute Times Using a Biomathematical Model of Fatigue

Jaime K. Devine, Jake Choynowski, Steven R. Hursh

Subject: Social Sciences, Behavior Sciences Keywords: daylight savings time; light exposure; fatigue risk; biomathematical modeling of fatigue; road safety; traffic

Online: 22 June 2023 (14:39:04 CEST)

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Preprint REVIEW | doi:10.20944/preprints202402.0048.v1

A Critical Review of Risk Assessment Models for Listeria monocytogenes in Seafood

Ursula Gonzales-Barron, Vasco Cadavez, Juliana De Oliveira Mota, Laurent Guillier, Moez Sanaa

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: systematic review; exposure assessment; simulation; fish; smoked salmon; listeriosis

Online: 1 February 2024 (13:54:47 CET)

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Preprint REVIEW | doi:10.20944/preprints202310.1649.v1

Photon-counting Detector CT in Vascular Imaging

Chiara Zanon, Filippo Cademartiri, Alessandro Toniolo, Costanza Bini, Alberto Clemente, Elda Chiara Colacchio, Giulio Cabrelle, Florinda Mastro, Michele Antonello, Emilio Quaia, Alessia Pepe

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Vascular; Photon-counting; CT Angiography; Dose Exposure; Contrast Agents; EVAR; Aorta; Endoleaks

Online: 25 October 2023 (12:36:34 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202306.0122.v1

Preexposure Prophylaxis against COVID-19 with Tixagevimab/Cilgavimab in Slovenian National Cohort of Kidney Transplant Recipients

Špela Borštnar, Miha Arnol, Željka Večerić Haler, Gregor Mlinšek

Subject: Medicine And Pharmacology, Internal Medicine Keywords: COVID 19; pre-exposure prophylaxis; kidney transplantation, tixagevimab/cilgavimab

Online: 2 June 2023 (03:58:07 CEST)

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