Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Environmental Exposures and Phenotype of Non-smoking COPD

Sameer Arbat
* ORCID logo ,
Ashok Arbat
,
Bharat Agrawal
,
Parimal Deshpande
,
Irfan Rahman
* ORCID logo ,
Swapnil Bakamwar
,
Prajakta Borkar
Version 1 : Received: 24 June 2022 / Approved: 24 June 2022 / Online: 24 June 2022 (08:18:34 CEST)

How to cite: Arbat, S.; Arbat, A.; Agrawal, B.; Deshpande, P.; Rahman, I.; Bakamwar, S.; Borkar, P. Environmental Exposures and Phenotype of Non-smoking COPD. Preprints 2022, 2022060334. https://doi.org/10.20944/preprints202206.0334.v1 Arbat, S.; Arbat, A.; Agrawal, B.; Deshpande, P.; Rahman, I.; Bakamwar, S.; Borkar, P. Environmental Exposures and Phenotype of Non-smoking COPD. Preprints 2022, 2022060334. https://doi.org/10.20944/preprints202206.0334.v1

Abstract

Chronic obstructive pulmonary disease (COPD) is strongly associated with tobacco smoking and it is the increasing cause of morbidity and mortality worldwide. The prevalence of COPD among never smokers varies widely across regions, areas, and nations. COPD in smokers has been extensively explored worldwide, however, COPD in non-smokers is under-explored and there is limited data available on non-smoking COPD. We determined the role of environmental pollution and biomass fuel exposure in COPD patients who were non-smokers. We evaluated the clinical profile of non-smokers with COPD in a retrospective observational study. 180 non-smoker COPD patients were selected from the year 2016-to 2018. We found that many patients with COPD are non-smokers and the incidence is higher among the rural population, suggesting that non-smoking COPD is evolving rapidly due to biomass smoke and other environmental pollutant exposures.

Keywords

non-smoking COPD; phenotypes; air pollution; biomass; occupational exposure

Subject

Medicine and Pharmacology, Immunology and Allergy

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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