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Preprint ARTICLE | doi:10.20944/preprints202305.0012.v1

Non-muscle Myosin Type-II Localization in the Mouse Intestinal Villi is Altered by B-Type Natriuretic Peptide

Anteneh Addisu, Yunus E. Dogan, Darrice Montgomery, Leeyu Addisu, Abdel A Alli

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Non-Muscle Myosin; BNP; GI epithelia; Apical junctional complex; Absorption

Online: 1 May 2023 (04:09:57 CEST)

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Our prior studies have shown that B type Natriuretic Peptide (BNP) decreases absorption from the gastrointestinal (GI) tract. Since non-muscle myosin-type II (NMM-II) is known to have a role in epithelial tight junction regulation, we aimed to test whether BNP has an effect on the localization and expression of NMM-II in the intestinal villi. We treated wild type mice with a 10 ng/g intravenous bolus of BNP followed by infusion of BNP at 1ng/g/minute vs. vehicle control. The mice were then euthanized and intestinal tissue isolated and sectioned. The tissue was immune-stained for NMM-II and examined using fluorescence microscopy. The tissue section not treated with antibody to NMM-II was used as a methodological control to evaluate the non-specific binding. Scanning electron micrographic images were taken to compare structural differences between the two groups. Western blotting was performed to compare the regional protein expression of NMM-II and associated proteins including smooth muscle actin, kinesin, and E cadherin in small intestinal tissue between BNP vs. vehicle infused mice. Fluorescence microscopy revealed markedly increased localization of NMM-II at the crypts and core of intestinal villi of the jejunum, ileum and colon of BNP treated mice compared to vehicle. Transmission electron microscopy revealed that the microvilli of BNP treated mice assumed the distinctive appearance of ‘relaxed’ microvilli compared to vehicle. Such decrease in contractility was previously shown to decrease para-cellular permeability of epithelia. Our observation indicates that BNP alters the localization of NMM-II in intestinal villi and makes the intestinal villi structures assume a state of decreased permeability of the apical junctional complex. Further characterization of this process and understanding the specific mediators involved could lead to the identification of novel therapeutic targets for various disease states such as heart failure and malabsorption.

Preprint ARTICLE | doi:10.20944/preprints202304.0890.v1

Investigation of Broadband Optical Nonlinear Absorption and Transient Dynamics in Orange IV Containing Azobenzene

Quanhua Wu, Rui Ruan, Xingxing Li, Yujie Zhao, Yang Li, Yu Fang, Yongqiang Chen, Quanying Wu, Yinglin Song, Xingzhi Wu

Subject: Physical Sciences, Optics And Photonics Keywords: Nonlinear optics; Z-scan; Transient absorption and refraction; Pump probe

Online: 25 April 2023 (05:40:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0538.v1

Evaluating Bagasse Ash as Partial Cement Replacement Material

Chala Basha, Amanuel Diriba, Habtamu Fekadu, Boki Tamiru, Abdi Biranu

Subject: Engineering, Civil Engineering Keywords: building materials; sugar cane bagasse; Portland cement; Concrete; water absorption

Online: 31 August 2022 (08:36:55 CEST)

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Preprint REVIEW | doi:10.20944/preprints202103.0057.v1

Lightinduced Effects in Amorphous Chalcogenide Glasses: Femtoseconds to Seconds

Pritam Khan, K. V. Adarsh

Subject: Physical Sciences, Acoustics Keywords: chalcogenide glasses; pump-probe; photodarkening; photobleaching; transient absorption, network rigidity

Online: 2 March 2021 (09:33:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0266.v1

Absorptive Desulfurization of Model Biogas Stream Using Choline Chloride-Based Deep Eutectic Solvents

Edyta Słupek, Patrycja Makoś

Subject: Chemistry And Materials Science, Chemical Engineering Keywords: deep eutectic solvents; absorption; biogas; dimethyl disulfide; green solvents; desulfurization

Online: 18 February 2020 (11:10:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints201905.0354.v1

New Perspective on Performances and Limits of Solar Fresh Air Cooling in Different Climatic Conditions

Ancuta C. Abrudan, Octavian G. Pop, Alexandru Serban, Mugur C. Balan

Subject: Engineering, Energy And Fuel Technology Keywords: Solar cooling; Absorption chiller; LiBr-H2O; Operating conditions; Climatic conditions

Online: 29 May 2019 (15:17:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201807.0376.v1

Self-Absorption Analysis of Silver Resonance Lines in Nano-Material Laser Produced Plasma

Ashraf M. El Sherbini, Mohamed A. Hagras , Mohamed R. Rizk , El-Sayed A. El Badawy, Christian G. Parigger

Subject: Physical Sciences, Atomic And Molecular Physics Keywords: laser-induced plasma; atomic spectroscopy; self-absorption; nanoparticles; silver; hydrogen

Online: 20 July 2018 (05:49:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201806.0402.v1

Single Scattering Albedo’s Spectral Dependence Effect on UV Irradiance

Ioannis-Panagiotis Raptis, Stelios Kazadzis, Kostas Eleftheratos, Vassilis Amiridis, Ilias Fountoulakis

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Solar Irradiance; SSA; Ultraviolet; Aerosols; Radiative Transfer; Absorption; UVA; UVB;

Online: 25 June 2018 (17:02:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0024.v1

Effect of Short Term Water Exposure on the Mechanical Properties of Halloysite Nanotubes-Multi Layer Graphene Reinforced Polyester Nanocomposites

Mohd Shahneel Saharudin, Rasheed Atif, Fawad Inam

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: nanocomposites; halloysite nanotubes; multi-layer graphene; water absorption; mechanical properties

Online: 5 January 2017 (09:34:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0006.v1

A New Method of Environmental Assessment and Monitoring of Heavy Metal Polluted Soil Using Fruticose Lichens

Yuri Sueoka, Masayuki Sakakibara, Sakae Sano, Yoshikazu Yamamoto

Subject: Environmental And Earth Sciences, Environmental Science Keywords: biomarker; environmental assessment; elemental competition; bioconcentration factor; heavy metal absorption

Online: 1 November 2016 (09:34:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints201609.0112.v1

Influence of External Magnetic Field on the Microwave Absorption Properties of Carbonyl Iron and Polychloroprene Composites Film

Haiyan Wang, Xueai Li

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: carbonyl iron; composites film; external magnetic field; microwave absorption properties

Online: 28 September 2016 (10:32:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.1337.v1

Impact of immunopathy and coagulopathy on multi-organ failure and mortality in a lethal porcine model of uncontrolled hemorrhagic shock

Milomir O. Simovic, James A Bynum, Bin Liu, Jurandir J. Dalle Lucca, Yansong Li

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: uncontrolled hemorrhagic shock, immunopathy, coagulopathy, MOF, mortality, swine, damage control resuscitation

Online: 18 December 2023 (13:03:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1889.v1

Reduction of Shock Wave Severity by Porous Media on a Two-Dimensional Obstacle in an Open Channel

Seyed Ehsan Hosseini, Omid Karimi

Subject: Engineering, Mechanical Engineering Keywords: compressible flow; numerical solution method; porous media; shock control; skin friction

Online: 30 October 2023 (10:12:41 CET)

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Preprint REVIEW | doi:10.20944/preprints202310.1327.v1

HSF1 Inhibition: A Novel Anti-Cancer Strategy with Promise for Precision Oncology

Khanisyah Erza Gumilar, Yeh Chin, Ibrahim H. Ibrahim, Brahmana A. Tjokroprawiro, Jer-Yen Yang, Ming Zhou, Natalie R. Gassman, Ming Tan

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: HSF1; heat shock response; cellular stress; cancer stem cells; tumor microenvironment

Online: 20 October 2023 (10:26:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1460.v1

Trade Performance of Bangladesh during Covid-19 Pandemic: An Empirical Study using CGE Model

Farha Fatema, Mohammad Monirul Islam, Tania Rahman

Subject: Business, Economics And Management, Business And Management Keywords: Covid-19; trade performance; Bangladesh; CGE model; demand shock; trade disruptions

Online: 21 August 2023 (11:58:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.2010.v1

The Effect of Cluster Nursing in ICU on Treatment Compliance and Intestinal Barrier Function in Patients with Refractory Septic Shock

Yun Chen, Yuefang Pan, Shunbo Xu

Subject: Medicine And Pharmacology, Surgery Keywords: care bundles; ICU; refractory septic shock; treatment compliance; intestinal barrier function

Online: 31 July 2023 (02:34:58 CEST)

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Objective: To evaluate the effect of care bundles on treatment compliance and intestinal barrier function in patients with refractory septic shock in the intensive care units (ICUs). Methods: In this retrospective study, the clinical data of 94 patients with refractory septic shock admitted to our hospital between June 2020 and April 2022 were collected. Patients with routine nursing were included in the routine group, and those with care bundles were assigned to the care bundles group, with 47 cases in each group. Outcome measures included nursing efficiency, treatment compliance, sequential organ failure assessment (SOFA) score, acute physiology and chronic health evaluation (APACHE II) score, intestinal barrier function, inflammation factor level, treatment outcome and complications. Results: Care bundles resulted in significantly higher nursing efficiency and treatment compliance versus routine care (P<0.05). Patients receiving care bundles showed significantly higher SOFA scores and APACHE II scores than those receiving routine care (P<0.05). Intestinal fatty-acid binding protein (I-FABP), diamine oxidase (DAO), lactate, endotoxin, and intestinal dysfunction scores in the care bundles group were significantly lower than those in the conventional group after treatment (P<0.05). Care bundles were associated with significantly lower levels of procalcitonin (PCT) and hypersensitive C-reactive protein (hsCRP), shorter time to symptom relief, ICU treatment time, and duration of mechanical ventilation, and lower 28-d morbidity and mortality versus routine care (P<0.05). Patients in the care bundles group had a significantly lower incidence of complications than those in the routine group (P<0.05). Conclusion: Care bundles effectively enhance treatment compliance, improve intestinal barrier function and treatment outcomes, reduce the inflammatory response, and decrease the risk of SOFA score, APACHE II score, and complications in patients with refractory septic shock.

Preprint ARTICLE | doi:10.20944/preprints202307.1799.v1

Polydeoxyribonucleotide and Shock Wave Therapy Sequence Efficacy in Regenerating Immobilized Rabbit Calf Muscles

Yoon-Jin Lee, Yong Suk Moon, Dong Rak Kwon, Sung Cheol Cho, Eun-Ho Kim

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Muscle atrophy; Polydeoxyribonucleotides; Extracorporeal shock wave therapy; Muscle regeneration; Rabbit models

Online: 26 July 2023 (10:50:58 CEST)

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Objective: The main purpose of the study is to investigate the combined effects of polydeoxyribonucleotide (PDRN) and extracorporeal shock wave therapy (ESWT) sequences on the regenerative processes in atrophied animal muscles. Methods: Thirty male New Zealand rabbits, aged 12 weeks, were divided into five groups: normal saline, PDRN, ESWT, PDRN injection before ESWT, and PDRN injection after ESWT. Following 2 weeks of cast immobilization, the respective treatments were administered to the atrophied calf muscles. Radial ESWT was performed twice weekly. The evaluation included measurements of calf circumference, tibial nerve compound muscle action potential (CMAP), and gastrocnemius (GCM) muscle thickness after 2 weeks of treatment. Histological and immunohistochemical staining, as well as Western blot analysis, were conducted 2 weeks post-treatment. Staining intensity and extent were assessed using semi-quantitative scores. Results: Groups 4 and 5 demonstrated significantly greater calf muscle circumference, GCM muscle thickness, tibial nerve CMAP, and GCM muscle fiber cross-sectional area (types I, II, and total) than in the remaining three groups (p < 0.05), while they did not did not differ significantly in these parameters. Groups 2 and 3 showed the higher values for all the observations compared to group 1 (p < 0.05). Group 4 had the greatest ratio of vascular endothelial growth factor (VEGF) to platelet endothelial cell adhesion molecule-1 (PECAM-1) in the gastrocnemius muscle fibers than in the other four groups (p < 0.05). Western blot analysis revealed significantly higher expression of angiogenesis cytokines in groups 4 and 5 than in the remaining (p < 0.05). Conclusion: The combination of ESWT and PDRN injection demonstrated superior regenerative efficacy for atrophied calf muscle tissue in rabbit models than these techniques alone or saline. Particularly, administering ESWT after PDRN injection yielded the most favorable outcomes in specific parameters.

Preprint ARTICLE | doi:10.20944/preprints202307.1594.v1

The Effect of Cluster Nursing in ICU on Treatment Compliance and Intestinal Barrier Function in Patients with Refractory Septic Shock

Yun Chen, Yuefang Pan, Shunbo Xu

Subject: Medicine And Pharmacology, Surgery Keywords: Care bundles; ICU; Refractory septic shock; Treatment compliance; Intestinal barrier function

Online: 24 July 2023 (10:30:31 CEST)

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Objective: To evaluate the effect of care bundles on treatment compliance and intestinal barrier function in patients with refractory septic shock in the intensive care units (ICUs). Methods: In this retrospective study, the clinical data of 94 patients with refractory septic shock admitted to our hospital between June 2020 and April 2022 were collected. Patients with routine nursing were included in the routine group, and those with care bundles were assigned to the care bundles group, with 47 cases in each group. Outcome measures included nursing efficiency, treatment compliance, sequential organ failure assessment (SOFA) score, acute physiology and chronic health evaluation (APACHE II) score, intestinal barrier function, inflammation factor level, treatment outcome and complications. Results: Care bundles resulted in significantly higher nursing efficiency and treatment compliance versus routine care (P<0.05). Patients receiving care bundles showed significantly higher SOFA scores and APACHE II scores than those receiving routine care (P<0.05). Intestinal fatty-acid binding protein (I-FABP), diamine oxidase (DAO), lactate, endotoxin, and intestinal dysfunction scores in the care bundles group were significantly lower than those in the conventional group after treatment (P<0.05). Care bundles were associated with significantly lower levels of procalcitonin (PCT) and hypersensitive C-reactive protein (hsCRP), shorter time to symptom relief, ICU treatment time, and duration of mechanical ventilation, and lower 28-d morbidity and mortality versus routine care (P<0.05). Patients in the care bundles group had a significantly lower incidence of complications than those in the routine group (P<0.05). Conclusion: Care bundles effectively enhance treatment compliance, improve intestinal barrier function and treatment outcomes, reduce the inflammatory response, and decrease the risk of SOFA score, APACHE II score, and complications in patients with refractory septic shock.

Preprint ARTICLE | doi:10.20944/preprints202301.0135.v1

The Post Shock Nonequilibrium Relaxation in a Hypersonic Plasma Flow Involving Reflection off A Thermal Discontinuity

Anna Markhotok

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: Hypersonic plasma dynamics; Optical Discharge; Shock wave structure; Non-equilibrium state

Online: 9 January 2023 (02:37:19 CET)

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Preprint ARTICLE | doi:10.20944/preprints202210.0087.v1

Molecular Characterization of the Stress Response of the Holothurian Central Nervous System

Sebastián Cruz-González, Eduardo Quesada-Díaz, Yamil Miranda-Negrón, Raúl García-Rosario, Humberto Ortiz-Zuazaga, José Enrique García-Arrarás

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Echinoderm; Heat shock proteins; Ubiquitin; Regeneration; RNA-seq; Spinal cord injury

Online: 8 October 2022 (03:02:32 CEST)

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Preprint REVIEW | doi:10.20944/preprints202208.0141.v1

Update on Current Concepts in Management of Severe Hemorrhagic Shock and Optimal Individualized Fluid Therapy in Critically Ill Polytrauma Patients

Alexandru Florin Rogobete, Stelian Adrian Ritiu, Ovidiu Horea Bedreag, Marius Papurica, Sonia Elena Popovici, Daiana Toma, Maria Alina Lupu, Diana Loreta Paun, Dragos Nicolae Garofil, Dan Corneci, Adriana Pistol, Elena Mihaela Pahontu, Liana Valeanu, Dorel Sandesc

Subject: Medicine And Pharmacology, Anesthesiology And Pain Medicine Keywords: hemorrhagic shock; multimodal monitoring; individualized therapy; fluid therapy; critical care; trauma

Online: 8 August 2022 (09:56:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0171.v1

Mechanically Enhanced Hydrophobic Metal Surfaces Enabled by 3D Gradient Structures

Xiaohan Zhang, Jian Liu, Min Xia, Yaowu Hu

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: Selective laser shock peening; Hydrophobic properties; Mechanical properties; 3D gradient structure

Online: 18 April 2022 (11:58:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0668.v1

Prolonged Infusion of ß-lactams Decreases Mortality in Patients with Septic Shock: A Retrospective Before-and-after Study

Daniel Christoph Richter, Maximilian Dietrich, Lazar Detelinov Lalev, Felix C.F. Schmitt, Mascha Onida Fiedler, Thomas Bruckner, Dominic Stoerzinger, Ute Chiriac, Sabrina Klein, Thilo Hackert, Thorsten Brenner, Alexander Brinkmann, Markus A Weigand

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: prolonged infusion; ß-lactams; septic shock; mortality; antibiotic therapy; critical care

Online: 27 May 2021 (13:13:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201811.0145.v1

Health and Establishment of Highway Plantings in Florida (United States)

Seth Blair, Andrew Koeser, Lara Roman, Gary Knox, Mack Thetford

Subject: Biology And Life Sciences, Forestry Keywords: Highway Beautification; Transplant Shock; Transportation; Tree Health; Tree Establishment; Urban Forestry

Online: 6 November 2018 (14:22:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints201704.0166.v1

Near-Infrared Spectroscopy-based Detector in Application of Intensive Care Unit Clinics

Ting Li, Fulin Zhong, Zishan Deng, Boan Pan, Zebin Li

Subject: Medicine And Pharmacology, Other Keywords: optoelectronic sensor; near-infrared spectroscopy; thrombus diagnosis; shock monitoring; fatigue evaluation

Online: 26 April 2017 (06:05:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202301.0454.v1

Stress-inducible SCAN Factors Suppress the Stress Response and Are Biomarkers for Enhanced Prognosis in Cancers

Takanori Eguchi, Mona Sheta, Stuart K Calderwood

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: cell stress response; heat shock protein 90 (HSP90); SCAN domain-containing proteins (SCAND); MZF1; heat shock factors (HSF); co-expression correlation; Kaplan-Meyer analysis; cancer patients prognosis

Online: 25 January 2023 (10:18:20 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1171.v1

Influence of Hypovolemia on Cardiac Function Measured by Transpulmonary Thermodilution. A Retrospective Cohort Study

Cecilia Gonzalez, Jesica Rodriguez Louzan, Agustin Traverso, Emanuele Papini, Agostina Giordana, Diana Latasa, Carlos Lovesio, Arnaldo Dubin

Subject: Medicine And Pharmacology, Internal Medicine Keywords: cardiac function; GEF limitation; global ejection fraction; TPTD; transpulmonary thermodilution; hypovolemic shock

Online: 21 February 2024 (08:05:51 CET)

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Background and Objectives Transpulmonary thermodilution has gained interest in recent years. It measures cardiac output (CO), stroke volume (SV), but also calculates global end diastolic indexed volume (GEDVI), and global ejection fraction (GEF). GEDVI is a static variable of cardiac preload. GEF provides information regarding cardiac function. GEF algorithm depends on SV and GEDVI. Therefore, in hypovolemic patients with decreased preload, SV or GEDVI could be decreased, and lead to altered GEF. The aim of our work was to evaluate whether impairment in GEDVI and SV may constitute a limitation for the interpretation of GEF in hypovolemic patients. A secondary objective was to determine factors independently associated with impaired GEF. Materials and Methods A retrospective study was conducted. Statistical analysis was performed by means of Mann Whitney and student t test. To determine correlation between GEF with SV, or GEF with GEDVI Pearson's coefficient was used. To determine factors independently associated with the presence of impaired GEF, binary logistic regression was performed. Results We included 113 patients with shock. Differences in mortality were detected in GEF (21[16-28] survivors versus 18 in non survivors[11-26]; p= 0.01). 38(34%) patients had hypovolemia. 44(39%) of them had depressed GEF values. Hypovolemic patients had lower GEF values than non-hypovolemic patients (16 [12-22] vs 20 [15-27]; p=0.01). Both SV and GEDVI had a statistically significant correlation with GEF (SV (Pearson's r 0.74; (p=0.00)) and GEDVI (Pearson's r -0.25; (p=0.00)). The only factors independently associated with low GEF were low SV and low GEDVI. Conclusion Hypovolemic patients frequently show low GEF values. We found correlation between SV and GEDVI with GEF. Low SV and low GEDVI were associated with low GEF. This could constitute a limitation in the interpretation of GEF and cardiac pump function. Hypovolemic patients could have low GEF without implying disorders in cardiac contractility.

Preprint ARTICLE | doi:10.20944/preprints202308.2030.v1

Simulation of Relaxation Processes in Hypersonic Flows with One-Temperature Non-Equilibrium Model

Anton Karpenko, Semen Tolstoguzov, Konstantin Volkov

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: aerodynamics; hypersonic flow; shock wave; physical and chemical processes; chemical kinetics; relaxation

Online: 30 August 2023 (08:54:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0455.v1

Effect of Shock Waves on the Growth of Aspergillus niger Conidia: Evaluation of Germination and Preliminary Study on Gene Expression

Daniel Larrañaga-Ordaz, Miguel Martínez-Maldonado, Blanca E Millán-Chiu, Franciso Fernández, Eduardo Castaño-Tostado, Miguel Ángel Gómez-Lim, Achim M Loske

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Shock waves; Acoustic cavitation; Gene expression; Aspergillus niger; Cell permeabilization; Fungal germination

Online: 26 August 2022 (09:34:23 CEST)

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Working Paper ARTICLE

FE Analysis of Laser Shock Peening on STS304 and the Effect of Static Damping on the Solution

Ryoonhan Kim, Jeong Suh, Dongsig Shin, Kwang-Hyeon Lee, Seung-Hoon Bae, Dae-Won Cho, Won-Geun Yi

Subject: Engineering, Mechanical Engineering Keywords: Laser shock peening; FE simulation; Residual stress; Minimum principal stress; Static damping

Online: 18 August 2021 (10:51:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202008.0257.v1

The Spectrum of Cardiovascular Complications in COVID-19- A Comprehensive Literature Review

Raja Shakeel Mushtaque, Rabia Mushtaque, Shahbano Baloch, Aadil Raza, Haseeb Bhatti, Zohaib Khan

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: COVID-19; SARS-CoV2; Acute Cardiac Injury; Arrhythmia; Heart Failure; Cardiogenic Shock

Online: 11 August 2020 (07:47:51 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202004.0150.v1

Cytoplasmic Increase of Hsp70 Protein: Potential New Biomarker of Early Infiltration of Cutaneous Squamous Cell Carcinoma Arising from Actinic Keratosis

Montserrat Fernandez-Guarino, José Javier Zamorano León, Antonio José López Farré, Maria Luisa Gonzalez Morales, Ana Isabel Sanchez Adrada, Jose Barrio Garde, Jose Antonio Arias Navalon, Pedro Jaen-Olasolo

Subject: Medicine And Pharmacology, Dermatology Keywords: actinic keratosis; cutaneous squamous cell carcinoma; cytoplams; skin cancer; heat shock protein

Online: 9 April 2020 (12:21:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0426.v1

Ion Acceleration in Multi-Fluid Plasma: Including Charge Separation induced Electric Field Effects in Supersonic Wave Layers

Ross Burrows

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: solitons; electrostatic solitary waves; pickup ions; perpendicular shock waves; multi-fluid plasma

Online: 29 March 2020 (06:53:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0083.v2

A Two-Phase Model of Air Shock Wave Induced by Rock-Fall in Closed Goaf

Fengyu Ren, Yang Liu, Jianli Cao, Rongxing He, Yuan Xu, Xi You, Yan-jun Zhou

Subject: Engineering, Civil Engineering Keywords: air shock wave; rock-fall; two-phase model; computational fluid dynamics (CFD)

Online: 23 January 2017 (09:15:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.2190.v1

Mechanical Properties of Lattice Structures With a Central Cube: Experiments and Simulations

Shuai Guo, Yuwei Ma, Peng Liu, Yang Chen

Subject: Engineering, Mechanical Engineering Keywords: Lattice structure; Energy absorption; Additive manufacturing; Printing defects; Finite element model

Online: 31 January 2024 (09:25:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.1593.v1

Cubic Nonlinearity of Graphene-Oxide Monolayer

Tikaram Neupane, Uma Poudyal, Bagher Tabibi, Wan-joong Kim, Felix Jaetae Seo

Subject: Physical Sciences, Optics And Photonics Keywords: One-photon; two-photon transition; Atomic layer; Nonlinear absorption; Nonlinear refraction

Online: 23 August 2023 (09:44:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1352.v1

Oral Iron Absorption of Ferric Citrate Hydrate and Hepcidin-25 in Hemodialysis Patients: A Prospective, Multicenter, Observational Riona-Oral Iron Absorption Trial

Naohisa Tomosugi, Yoshitaka Koshino, Chie Ogawa, Kunimi Maeda, Noriaki Shimada, Kimio Tomita, Shoichiro Daimon, Tsutomu Shikano, Kazuyuki Ryu, Toru Takatani, Kazuya Sakamoto, Satonori Ueyama, Daisuke Nagasaku, Masato Nakamura, Shibun Ra, Masataka Nishimura, Chieko Takagi, Yoji Ishii, Noritoshi Kudo, Shinsuke Takechi, Takashi Ishizu, Takamoto Yanagawa, Masamichi Fukuda, Yutaka Nitta, Takayuki Yamaoka, Taku Saito, Suzuko Imayoshi, Momoyo Omata, Joji Oshima, Akira Onozaki, Hiroaki Ichihashi, Yasuhisa Matsushima, Hisahito Takae, Ryoichi Nakazawa, Koichi Ikeda, Masato Tsuboi, Keiko Konishi, Shouzaburo Kato, Maki Ooura, Masaki Koyama, Tsukasa Naganuma, Makoto Ogi, Shigeyuki Katayama, Toshiaki Okumura, Shigemi Kameda, Sayuri Shirai

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: oral iron absorption; ferric citrate hydrate; hemodialysis; hepcidin-25; iron shift

Online: 18 August 2023 (11:20:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0324.v1

Porous Gold Nanoparticles: Thermal Stability, Optical Response and Support-Free Synthesis

Laura Juhász, Zoltán Erdélyi, Csaba Cserháti

Subject: Chemistry And Materials Science, Nanotechnology Keywords: porous gold nanoparticles; plasmons, optical absorption,; dewetting, dealloying; support-free nanoparticles

Online: 5 June 2023 (13:20:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0965.v1

Luminescence Properties of Epitaxial Cu₂O Thin Films Electrodeposited on Metallic Substrates and Cu₂O Single Crystals

Laima Trinkler, Dajin Dai, Liuwen Chang, Mitch Ming Chi Chou, Tzu-Ying Wu, Jevgenijs Gabrusenoks, Dace Nilova, Rihards Ruska, Baiba Berzina, Ramunas Nedzinskas

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: cuprous oxide; single crystal; epitaxial thin films; electrodeposition; photoluminescence; optical absorption.

Online: 26 April 2023 (07:27:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0569.v1

Development and Evaluation of Self-Microemulsifying Drug Delivery System for Improving Oral Absorption of Poorly Water-soluble Olaparib

Yong-Han Kim, Seong-Bo Kim, Se-Hui Choi, Thi-Thao-Linh Nguyen, Sung-Hoon Ahn, Kyung-Sun Moon, Kwan Hyung Cho, Taeyong Sim, Eun-Ji Heo, Sungtae Kim, Han-Gon Choi, Dong-Jin Jang

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Olaparib; self-microemulsifying drug delivery system; microemulsion; solubility; dissolution; oral absorption

Online: 19 April 2023 (08:16:05 CEST)

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The purpose of this study is to develop and evaluate a self-microemulsifying drug delivery system (SMEDDS) to improve the oral absorption of poorly water-soluble Olaparib. Through the solubility test of Olaparib in various oils, surfactants and co-surfactants, pharmaceutical excipients for use in SMEDDS manufacturing were selected. Self-emulsifying regions were identified by mixing the selected materials at various ratios, and a pseudoternary phase diagram was constructed by synthesizing these results. Various physicochemical properties of microemulsion incorporating Olaparib were confirmed by investigating the particle morphology, particle size, zeta potential, drug content and stability. In addition, the improved dissolution and oral absorption of Olaparib were also confirmed through a dissolution test and a pharmacokinetic study. An optimal microemulsion was generated in the formulation of Capmul MCM EP/NF 10%, Labrasol 80% and PEG 400 10%. Fabricated nano-sized microemulsions were well-dispersed in aqueous solutions, and it was also confirmed that it was maintained well without any problems of either physical or chemical stability. The 5 min initial dissolution of Olaparib in fabricated formulations was improved by 10.6 times (pH1.2), 14.8 times (pH6.8) and 14.8 times (distilled water) compared to the values of Olaparib powder. The dissolution at 120min was 45.4±4.0%(pH1.2), 53.5±1.1% (pH6.8) and 58.1±1.00% (distilled water) in Olaparib powder but has been significantly improved by 1.7 times (74.8±1.9%), 1.6 times (84.2±0.3%) and 1.5 times (81.2±0.7%) in SMEDDS. Associated with the high dissolutions of Olaparib in fabricated microemulsions, the pharmacokinetic parameters were also greatly improved. The Cmax and AUCinf of Olaparib in the prepared microemulsion were increased 4.2- and 3.2-fold, respectively, compared to powder. Taken together with the results mentioned above, the microemulsion system could be an effective tool as an oral delivery formulation for Olaparib. Additionally, our results demonstrate that the SMEDDS systems comprising Capmul MCM, Labrasol and PEG 400 could be a useful option for improvement of several other poorly water-soluble drugs with physico-chemical properties similar to Olaparib.

Preprint ARTICLE | doi:10.20944/preprints202203.0382.v1

The Characteristic of CFRP Laminates Related to Water Absorption Subjected to Tensile, Bending, and Compression

Sudarisman Sudarisman, Alfian Hidayat, Haniel Haniel, Muhammad Tiopan, Rela Adi Himarosa, Muhammad Akhsin Muflikhun

Subject: Engineering, Mechanical Engineering Keywords: CFRP; vacuum infusion; water absorption; tensile test; bending test; compressive test

Online: 29 March 2022 (12:22:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202008.0229.v1

Evaluation of the CDOM Absorption Coefficient in the Arctic Seas by Sentinel-3 OLCI Data

Dmitry Glukhovets, Oleg Kopelevich, Anna Yushmanova, Svetlana Vazyulya, Sergey Sheberstov, Polina Karalli, Inna Sahling

Subject: Environmental And Earth Sciences, Oceanography Keywords: OLCI Sentinel-3; Barents; Kara seas; absorption coefficient; uncertainties; field data

Online: 9 August 2020 (22:31:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0458.v1

Effect of Structural Parameters and Materials on the Mechanical Characteristics of Expansion Tube

Zizhen Qi, Yuwu Zhang, and Yuliang Lin

Subject: Engineering, Mechanical Engineering Keywords: expansion tube; mechanical properties; energy absorption; parent material comparison; plastic deformation

Online: 20 July 2020 (08:10:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201908.0085.v1

Synthesis, Characterization, and Crystal Structure Determination of a New Lithium Zinc Iodate Polymorph LiZn(IO₃)₃

Zoulikha Hebboul, Christine Galez, Djamal Benbertal, Sandrine Beauquis, Yannick Mugnier, Abdelnour Benmakhlouf, Mohamed Bouchenafa, Daniel Errandonea

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: iodate; crystal structure; x-ray diffraction; density functional theory; infrared absorption

Online: 7 August 2019 (03:42:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201902.0001.v2

Effects of Continuous Deep Fat Frying on the Physical and Chemical Properties of Assorted Brands of Edible Cooking Oils Sold in Metropolitan Kampala

Timothy Omara, Erisa Kigenyi

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: color; free fatty acids; iodine absorption value; paraanisidine value; peroxide value

Online: 6 February 2019 (06:36:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints201809.0547.v1

Exotic spectra and lattice vibrations of ice X using the DFT method

Lu Jiang, Shu-Kai Yao, Kai Zhang, Ze-Ren Wang, Hui-Wen Luo, Xu-Liang Zhu, Yue Gu, Peng Zhang

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: ice X; vibrational spectrum; first-principles DFT; Raman scattering; IR absorption

Online: 27 September 2018 (13:25:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201809.0160.v1

Acoustic Properties of Composite Synthesized from Activated Zeolite and Fibre

Hidjan Hidjan, Sutanto Sutanto, Nanang Rohadi

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Sound Absorption Coefficient; Noise; Activated Zeolite; Banana Stem Fibre; Acoustical material

Online: 10 September 2018 (09:32:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201702.0011.v1

Simulation Analysis of Solution Transportation Absorption Chiller with the Capacity from 25 RT to 1000 RT

Koji Enoki, Fumi Watanabe, Seigo Tanaka, Atsushi Akiwawa, Toshitaka Takei

Subject: Engineering, Energy And Fuel Technology Keywords: absorption chiller; thermal energy transportation; solution transportation; ammonia-water; COP; simulation

Online: 4 February 2017 (07:49:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0136.v1

Impact of CytoSorb Hemoadsorption Therapy on Fluid Balance in Patients with Septic Shock

Klaus Kogelmann, Tobias Huebner, Matthias Drüner, Dominik Jarczak

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: Inflammation; septic shock; CytoSorb; hemoadsorption; fluid balance; vasopressors; vascular barrier function; endothelial integrity

Online: 5 December 2023 (06:12:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.0245.v1

New Insights into Flow for a Low-Bypass-Ratio Transonic Fan with Optimized Rotor

Mingjun Liu, Zhenjiu Zhang, Zhuoming Liang, Haibing Xiao, Huanlong Chen, Xianqing Yang, Changxiao Shao

Subject: Engineering, Aerospace Engineering Keywords: low-bypass-ratio transonic fan; aerodynamic optimization; vortex dynamics; secondary flow; shock wave

Online: 5 October 2023 (02:12:19 CEST)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202309.0655.v1

Temporary Mechanical Circulatory Support in Cardiogenic Shock Patients after Cardiac Procedures: Selection Algorithm and Weaning Strategies

Gaik Nersesian, Sascha Ott, Alexander Fardman, Pia Lanmueller, Daniel Lewin, Alexander Bernhardt, Fabian Emrich, Gloria Faerber, Gábor Szabó, Mehmet Oezkur, Bernd Panholzer, Sebastian Rojas Hernandez, Diyar Saeed, Bastian Schmack, Gregor Warnecke, Daniel Zimpfer, Herko Grubitzsch, Volkmar Falk, Evgenij Potapov

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: postcardiotomy cardiogenic shock; mechanical circulatory support; extracorporeal life support; microaxial flow pump; Impella

Online: 11 September 2023 (09:58:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0698.v1

Health Shock, Borrowing, and Rural Household Welfare: Evidence from China

Xinyu ZHANG

Subject: Business, Economics And Management, Economics Keywords: Health Shock, Credit, Rural Household Welfare, Sustainable Rural Devlopment, China Household Finance Survey

Online: 9 August 2023 (08:50:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0325.v1

Breeding Substrate Containing Distillation Residues of Mediterranean Medicinal Aromatic Plants Modulates the Effects of Tenebrio molitor as Fishmeal Substitute on Blood Signal Transduction and WBC Activation of Gilthead Seabream (Sparus aurata)

Efthimia Antonopoulou, Markos Kolygas, Nikolas Panteli, Evangelia Gouva, Panagiota Kontogeorgiou, Konstantinos Feidantsis, Achileas Chatzopoulos, Konstantina Bitchava, Christos Zacharis, Eleftherios Bonos, Ιlias Giannenas, Ioannis Skoufos, Stefanos S. Andreadis, Georgios Skoulakis, Christos G. Athanassiou, Cosmas Nathanailides

Subject: Biology And Life Sciences, Life Sciences Keywords: Tenebrio molitor; gilthead sea bream; differential leukocyte count; MAPK signaling; heat shock proteins

Online: 3 August 2023 (10:48:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0087.v1

Interrelation Midst Low T3 Levels, Type 3 Deiodinase, Oxidative Stress And Mortality In Sepsis and Septic Shock: Defining Patient Outcome

Josi Vidart, Luiza Axelrud, Andre Cardozo Braun, Rafael A. Marschner, Simone Magagnin Wajner

Subject: Medicine And Pharmacology, Hematology Keywords: low T3 syndrome, oxidative stress, sepsis, septic shock, thyroid hormone, type 3 deiodinase

Online: 6 December 2022 (02:18:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202205.0089.v1

HSPA1B is the Dominant Partner in the HSPA1A/HSPA1B Mediated Proteotoxic Stress Response in Placenta-Derived Stem Cells

Bothina Mohammed Alharbi, Aisha Bugshan, Azhaar Almozel, Reem Alenzi, Abderrezak Bouchama, Tanvir Khatlani, Sameer Mohammad, Shuja Shafi Malik

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: placenta-derived stem cells; placenta; stem cells; proteostasis; heat-shock; chaperones; HSPA1B; HSPA1A

Online: 7 May 2022 (03:37:17 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202103.0192.v1

Radial Extracorporeal Shock Wave Therapy to Support Breathing in Case of Coronavirus Disease 2019 (COVID-19): A Case Report

Peter Stiller, Christoph Schmitz

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: COVID-19; shortness of breath; chest pain; radial extracorporeal shock wave therapy; rESWT

Online: 5 March 2021 (17:02:02 CET)

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Preprint REVIEW | doi:10.20944/preprints202010.0292.v1

A Critical Review of the Material Characteristics of Additive Manufactured IN718 for High Temperature Application

Ching Kiat Yong, Gregory J. Gibbons, Geoff West

Subject: Chemistry And Materials Science, Biomaterials Keywords: laser powder bed fusion; Inconel 718; high temperature; material characterisation; laser shock peening

Online: 14 October 2020 (09:11:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202009.0369.v1

Impact on Mechanical Properties and Microstructural Response of Nickel-Based Super-Alloy GH4169 Subjected to Warm Laser Shock Peening

Ying Lu, Yuling Yang, Jibin Zhao, Yuqi Yang, Hongchao Qiao, Xianliang Hu, Jiajun Wu, Boyu Sun

Subject: Engineering, Mechanical Engineering Keywords: warm laser shock peening (WLSP); GH4169 nickel-base super-alloy; microstructure; residual stress

Online: 17 September 2020 (04:12:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1593.v1

Comparative Simulation of Plasmonic Nanostructures: Optical Response of Periodic Metal Nanostrip and Nanodisk Arrays on Mirror

Niloofar Ebrahimzadeh Esfahani, Jaroslav Kováč, Jr., Giuseppe Maruccio, Silvia Rizzato, Soňa Kováčová

Subject: Engineering, Electrical And Electronic Engineering Keywords: Nanodisk; nanostrip; plasmonic; field enhancement; absorption; scattering cross section; extinction cross section

Online: 26 March 2024 (11:54:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1371.v1

The Influence of Geometry on the Energy Capture of a Point Absorber Wave Energy Converter in the Coast of Mexico

Alejandro Martinez Flores, Ayrton Alfonso Medina Rodríguez, Edgar Mendoza, Rodolfo Silva

Subject: Engineering, Other Keywords: Wave energy converter, heaving buoy, mild slope equation, hydrodynamic response, energy absorption.

Online: 23 February 2024 (11:14:41 CET)

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Preprint REVIEW | doi:10.20944/preprints202402.0386.v1

Integrated Photonic Sensors with Enhanced Evanescent Field: Unveiling the Dynamic Interaction with the Ambient Medium

Muhammad A. Butt

Subject: Physical Sciences, Optics And Photonics Keywords: Evanescent field; photonic sensor; optical waveguide; light-matter interaction; absorption; mid-infrared.

Online: 6 February 2024 (15:36:54 CET)

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Preprint REVIEW | doi:10.20944/preprints202401.1066.v1

Toxicity Tolerance in the Carcinogenesis of Environmental Cadmium

Aleksandar Cirovic, Soisungwan Satarug

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: cadmium; cancer; cell transformation; copper; intestinal absorption; iron store status; zinc transporters

Online: 15 January 2024 (10:27:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0416.v1

Analysis of the Optical Properties and Electronic Structure of Semiconductors of the Cu2NiXS4 (X = Si, GE, Sn) Family as New Promising Materials for Optoelectronic Devices

Dilshod Nematov

Subject: Physical Sciences, Condensed Matter Physics Keywords: bandgap; kesterites; optical properties; solar cells; absorption coefficient; dielectric constant; photoelectric applications

Online: 4 January 2024 (15:15:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1627.v1

Natural Gas Sweetening via Membrane-Assisted Gas Absorption. Part 1: A Hollow-Fiber Unit with MDEA-Based Absorbent

Anton Petukhov, Artem Atlaskin, Kirill Smorodin, Mariia Atlaskina, Dmitriy Mikhailovich Zarubin, Nikita S. Tsivkovsky, Sergey Kryuchkov, Anna Stepakova, Andrey Vorotyntsev, Olga Kazarina, Sergey Suvorov, Ekaterina Stepanova, Ilya Vorotyntsev

Subject: Chemistry And Materials Science, Chemical Engineering Keywords: membrane-assisted gas absorption; natural gas processing; sweetening; gas separation; hollow fibers

Online: 21 December 2023 (08:37:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1486.v1

Antiviral Efficacy of Heparan Sulfate and Enoxaparin Sodium against SARS-CoV-2: An In-Vitro/in-Silico Model

Virginia Fuochi, Salvatore Furnari, Giuseppe Floresta, Vincenzo Patamia, Chiara Zagni, Filippo Drago, Antonio Rescifina, Pio Maria Furneri

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: heparan sulfate; enoxaparin; coronavirus; SARS-CoV-2; ACE2, absorption inhibition; molecular docking

Online: 24 October 2023 (08:12:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0037.v1

Comparison of the Mechanical Properties of Fiber Reinforced Shotcrete at Laboratory and On-Site Conditions

Ramiro Castellanos Castellón, Marcos G. Alberti, Jaime C. Galvez, José Vera-Agullo, Raul Pina-Zapardiel

Subject: Engineering, Civil Engineering Keywords: Fracture energy (GF); energy absorption capacity (E25mm); residual flexural strength(fRj); fibers

Online: 3 June 2022 (09:46:23 CEST)

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Preprint DATA DESCRIPTOR | doi:10.20944/preprints202202.0305.v1

Theoretical Calculations and Analysis Method of the Physicochemical Properties of Phytochemicals to Predict Gastrointestinal Absorption

Luis A. Vélez, Yamixa Delgado, Yancy Ferrer-Acosta, Ivette J. Suárez-Arroyo, Priscilla Rodríguez, Daraishka Pérez

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Physicochemical properties; Gastrointestinal absorption; Lipinski's rules; Veber's rules; Ghose's rules; Muegge's rules

Online: 24 February 2022 (08:35:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202111.0114.v1

Channel Modeling for In-body Optical Wireless Communications

Stylianos E. Trevlakis, Alexandros-Apostolos A. Boulogeorgos, Nestor D. Chatzidiamantis, George K. Karagiannidis

Subject: Engineering, Electrical And Electronic Engineering Keywords: Absorption coefficient; biomedical engineering; fitting; machine learning; optical properties; pathloss; scattering coefficient.

Online: 5 November 2021 (10:38:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0222.v1

Detection of Heavy Metals in Water Using Graphene Quantum Dots: An Experimental and Theoretical Study

Lorenzo Gontrani, Olivia Pulci, Marilena Carbone, Roberto Pizzoferrato, Paolo Prosposito

Subject: Chemistry And Materials Science, Biomaterials Keywords: Graphene oxide; Quantum Dots; TD-DFT; Absorption; Quenching effect; Concentration; Optical Response

Online: 9 July 2021 (13:22:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0217.v1

Analysis of Heat Absorption and Collection Based on Solid Structures Collector

Yan Liu, Wenbin Liu, Qing Gao, Yong Huang, Peizhuo Li, Yongzhen Wang

Subject: Engineering, Automotive Engineering Keywords: solar collection; solid structure; heat absorption analysis; collection heat analysis; reflection spectrum

Online: 8 June 2021 (12:06:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202008.0692.v1

Exciton Coupling and Conformational Changes Impacting the Optical Properties of Metal Organic Frameworks

Andreas Windischbacher, Luca Steiner, Ritesh Haldar, Christof Wöll, Egbert Zojer, Anne-Marie Kelterer

Subject: Chemistry And Materials Science, Nanotechnology Keywords: metal organic frameworks; SURMOF; absorption; emission; time-dependent density functional theory; aggregation

Online: 31 August 2020 (04:11:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201909.0049.v1

Deriving Aerosol Absorption Properties from Solar Ultraviolet Radiation Spectral Measurements at Thessaloniki, Greece

Ilias Fountoulakis, Athanasios Natsis, Nikolaos Siomos, Theano Drosoglou, Alkiviadis F. Bais

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: solar UV radiation; aerosol absorption; SSA; AAOD; spectral measurements; aerosol optical properties

Online: 4 September 2019 (14:29:58 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints201908.0192.v1

Generation of Optical Absorption Band in Colloidal Coffee at Extremely Alkaline pH

Arindam Kushagra, Akshaya Pandey

Subject: Chemistry And Materials Science, Applied Chemistry Keywords: caffeine; colloidal coffee; optical absorption; pH sensor; solute-solvent interactions; UV absorber

Online: 19 August 2019 (04:14:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201906.0221.v1

Opacity Corrections for Resonance Silver Lines in Nano-Material Laser-Induced Plasma

Ashraf M. EL Sherbini, Tharwat M. EL Sherbini, Christian G. Parigger

Subject: Physical Sciences, Atomic And Molecular Physics Keywords: laser-induced plasma; atomic spectroscopy; self-reversal; self-absorption; nanoparticles; silver; hydrogen

Online: 22 June 2019 (11:43:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201901.0295.v1

Experimental Observation of Temperature-Driven Topological Phase Transition in HgTe/CdHgTe Quantum Wells

Maksim Zholudev, Aleksandr Kadykov, Mikhail Fadeev, Michal Marcinkiewicz, Sandra Ruffenach, Christophe Consejo, Wojciech Knap, Jeremie Torres, Sergey Morozov, Vladimir Gavrilenko, Nikolay Mikhailov, Sergey Dvoretskii, Frederic Teppe

Subject: Physical Sciences, Condensed Matter Physics Keywords: topological insulator; phase transition; mercury cadmium telluride; Landau levels; magneto-absorption; magnetotransport

Online: 29 January 2019 (16:44:14 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints201806.0353.v1

Electronic Excitations and Radiation Damage in Macromolecular Crystallography

José Brandão-Neto, Leonardo Bernasconi

Subject: Chemistry And Materials Science, Biomaterials Keywords: macromolecular crystallography; X-ray diffraction; radiation damage; absorption; electronic excitations; quantum chemistry

Online: 22 June 2018 (08:15:27 CEST)

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Preprint REVIEW | doi:10.20944/preprints201805.0096.v1

Acoustic Metamaterials in Aeronautics

Giorgio Palma, Huina Mao, Lorenzo Burghignoli, Peter Göransson, Umberto Iemma

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: metamaterials; aviation noise; aeroacoustics; noise absorption; noise reflection; noise trapping; acoustic cloaking

Online: 4 May 2018 (15:05:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201802.0097.v1

Estimating Chlorophyll-a Absorption with the Total Algae Peak Integration Retrieval TAPIR Considering Chlorophyll-a Fluorescence from Hyperspectral Top of the Atmosphere Signals in Optically Complex Waters

Therese Keck, René Preusker, Jürgen Fischer

Subject: Environmental And Earth Sciences, Oceanography Keywords: fluorescence; absorption; chlorophyll-a; remote sensing; hyperspectral; ocean color; IOP; TAPIR; EnMAP

Online: 14 February 2018 (07:11:09 CET)

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Preprint BRIEF REPORT | doi:10.20944/preprints202401.0889.v1

Impact of Mechanical Circulatory Support Timing on Outcomes in Myocardial Infarction-Related Cardiogenic Shock: Subanalysis of the PREPARE CS Registry

Dan Mihai Prunea, Eva Bachl, Lukas Herold, Sadeek Sidney Kanoun Schnur, Sascha Pätzold, Siegfried Altmanninger-Sock, Gudrun Angelika Sommer, Theresa Glantschnig, Ewald Kolesnik, Markus Wallner, Klemens Ablasser, Heiko Bugger, Eva Buschmann, Andreas Praschk, Friedrich M. Fruhwald, Albrecht Schmidt, Dirk Von Lewinski, Gabor Toth-Gayor

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: cardiogenic shock; mechanical circulatory support; myocardial infarction; mechanical circulatory support timing; in-hospital mortality

Online: 11 January 2024 (08:10:58 CET)

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Working Paper ARTICLE

Hspb1 Is Essential for Inducing Resistance to Proteotoxic Stress In Beta-Cells

Vinícius M. Gomes, Rosangela A. M. Wailemann, Gabriel S. Arini, Talita C. de Oliveira, Daria Raquel Queiroz, Ancély F. dos Santos, Letícia F. Terra, Stephan Lortz, Leticia Labriola

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: heat shock proteins; Diabetes mellitus; beta-cells; endoplasmic reticulum stress; proteostasis; HSPB1; cytoprotection; apoptosis.

Online: 8 July 2021 (14:03:59 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202102.0110.v1

Zika E Glycan Loop Region and Guillain-Barré Syndrome-Related Proteins: A Possible Molecular Mimicry to be Taken in Account for Vaccine Development

Lebeau Grégorie, Frumence Etienne, Turpin Jonathan, Hoarau Jean-jacques, Gadea Gilles, Krejbich Pascale, Despres Philippe, Wildriss Viranaicken

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: ZIKV; Guillain-Barré Syndrome; Molecular Mimicry; Calcium Channel Voltage Dependent; Heat Shock Protein; Vaccine

Online: 3 February 2021 (10:18:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints202004.0297.v1

Gold Nanoparticle Mediated Multi-Modal CT Imaging of 3 Hsp70 Membrane Positive Tumors

Melanie A. Kimm, Maxim Shevtsov, Caroline Werner, Wolfgang Sievert, Zhiyuan Wu, Oliver Schoppe, Bjoern H. Menze, Ernst J. Rummeny, Roland Proksa, Olga Bystrova, Marina Martynova, Gabriele Multhoff, Stefan Stangl

Subject: Biology And Life Sciences, Biophysics Keywords: gold nanoparticle; heat shock protein 70; molecular imaging; biomarker; spectral-CT; k-edge imaging

Online: 17 April 2020 (08:42:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201905.0054.v2

Is Radial Extracorporeal Shock Wave Therapy Combined with a Specific Rehabilitation Program (rESWT + RP) More Effective than Sham-rESWT + RP for Acute Hamstring Muscle Complex Injury Type 3b in Athletes? Study Protocol for a Prospective, Randomized, Double-Blind, Sham-Controlled Single Centre Trial

Javier Crupnik, Santiago Silveti, Natalia Wajnstein, Alejandro Rolon, Alisa Vollhardt, Peter Stiller, Christoph Schmitz

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: acute hamstring muscle complex injury; radial extracorporeal shock wave therapy; rESWT, RSWT; soccer medicine

Online: 14 July 2019 (09:01:08 CEST)

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Background: Acute injuries of the hamstring muscle complex (HMC) Type 3b (interfascicle / bundle-tear) are frequently observed in various sports disciplines both in elite and recreational sport. The treatment of choice of acute HMC injuries Type 3b is a progressive physiotherapeutic exercise program. Besides this, there is currently only insufficient scientific evidence to support other treatment methods, including local infiltrations and injections of platelet-rich-plasma. Very recently it was demonstrated that extracorporeal shock wave therapy (ESWT) may accelerate regeneration after acute skeletal muscle injury. The aim of the present study is to test the hypothesis that the combination of radial ESWT (rESWT) and a specific rehabilitation program (RP) is effective and safe in treatment of acute HMC injury Type 3b in athletes, and is statistically significantly more effective than the combination of sham-rESWT and RP. Methods/Design: We will perform a double blind, randomized, sham-controlled clinical trial at the clinic KinEf Kinesiología Deportiva, Ciudad Autónoma de Buenos Aires, Argentina. Fourty patients with acute HMC injury Type 3b will be randomly allocated to receive either rESWT (nine rESWT sessions; three sessions per week; 2500 radial extracorporeal shock waves (rESWs) per session; energy density depending on what the patient tolerates) or sham-rESWT. In addition, all patients will receive a specific rehabilitation program that will last for eight weeks. The primary outcome measure will be the individual time (days) necessary to return to play. Secondary outcomes will include the presence or absence of reinjury during a time period of six months after inclusion into the study. Discussion: Because of the lack of adequate treatment options for acute HMC injury Type 3b in athletes and particularly the high reinjury rate, we hypothesize that the results of this trial will be of importance and have impact on clinical practice. Trial registration: ClinicalTrials.gov ID NCT03473899. Registered March 22, 2018.

Preprint ARTICLE | doi:10.20944/preprints201810.0211.v1

Lipoprotein Cholesterols Are Stored in High-Resistant, Metastatic Cancer Cells and Released Upon Stress: Implication for a Mechanism Underlying Hypocholesterolemia in Cancer Patients

Taka Eguchi, Chiharu Sogawa, Kisho Ono, Mami Itagaki, Masaki Matsumoto

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: lipoprotein; extracellular vesicles; exosome; ectosome; stress response; resistant cancer; metastatic cancer; heat shock stress

Online: 10 October 2018 (09:44:17 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202306.1416.v1

Behavior of C₇₀ Fullerene in a Binary Mixture of Xylene and Tetrahydrofuran

Urol K Makhmanov, Shaxboz A Esanov, Dostonbek T Sidigaliev, Kayyum N Musurmonov, Bobirjon A Aslonov, Tohirjon A Chuliev

Subject: Physical Sciences, Optics And Photonics Keywords: C70 fullerene; xylene/tetrahydrofuran; self-organization; refractive index; DLS; UV-Vis absorption; nanocluster

Online: 20 June 2023 (09:35:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.1001.v1

Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin

Sukhontha Hasatsri, Jariya Suthi, Nattaporn Siriwut, Onjira Charoensappakit

Subject: Chemistry And Materials Science, Biomaterials Keywords: Eclipta prostrata; gelatin; foam dressing; wound dressing; physical property; absorption; dehydration; pH environment

Online: 26 April 2023 (15:23:50 CEST)

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Preprint REVIEW | doi:10.20944/preprints202204.0162.v1

Photoinduced Electron Transfer in Organized Assemblies. Case Studies

Antonio Santoro, Giovanni Bella, Ambra Maria Cancelliere, Scolastica Serroni, Giuliana Lazzaro, Sebastiano Campagna

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: Electron transfer; artificial photosynthesis; supramolecular assemblies; Donor-bridge-acceptor system; transient absorption spectroscopy

Online: 18 April 2022 (09:29:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202111.0022.v1

Genotoxicity of PM2.5 and PM1.0 Particulates on Human Peripheral Blood Lymphocytes in Manila, Philippines

Ma. Katrina Gale Estonilo, Joedith Anne Cazeñas, Carlos Josef Villafuerte, Custer Deocaris, Gloriamaris Caraos, Gerardo Jose Robles, Maria Cecilia Galvez, Celia Asaad, Edgar Vallar

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Particulate Matter; Genotoxicity; Peripheral Blood Lymphocytes; Atomic Absorption Spectroscopy; In-vitro Micronucleus Test

Online: 1 November 2021 (15:22:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202104.0445.v1

Phase Correction for Absorption Mode Two-dimensional Mass Spectrometry

Marc-André Delsuc, Kathrin Breuker, Maria A. van Agthoven

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: mass spectrometry; two-dimensional; tandem mass spectrometry; phase correction; absorption mode; data processing

Online: 16 April 2021 (12:41:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201911.0028.v1

Hydrogen Sensor Based on Tunable Diode Laser Absorption Spectroscopy

Viacheslav Avetisov, Ove Bjoroey, Junyang Wang, Peter Geiser, Ketil Gorm Paulsen

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: gas sensor; hydrogen sensor; diode laser; TDLAS; WMS; absorption spectroscopy; laser spectroscopy; hydrogen

Online: 3 November 2019 (18:21:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints201610.0050.v1

Investigation of Physical Characteristics of Non-Structural Lightweight Aggregate Blocks

Hamid Reza Ashrafi, Marzieh Sadat Moayyeri, Peyman Beiranvand

Subject: Engineering, Civil Engineering Keywords: non-load-bearing lightweight blocks; lightweight aggregates; density; compressive strength; water absorption volume

Online: 13 October 2016 (12:01:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1893.v1

Disturbance Observer-Based Anti-shock Controller for Laser Beam Steering Systems

Jung-Gon Kim

Subject: Control And Systems Engineering, Engineering Keywords: laser beam steering; fast-steering mirror; tip-tilt control system; anti-shock controller; disturbance observer

Online: 29 April 2024 (09:56:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0852.v1

Balloon Valvuloplasty In Congenital Critical Aortic Valve Stenosis – A Rescue Procedure For The Left Ventricle

Jochen Pfeifer, Axel Rentzsch, Martin Poryo, Hashim Abdul-Khaliq

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: critical aortic valve stenosis; transcatheter balloon valvuloplasty; retrieval loop; neonate; cardiogenic shock; left ventricular dysfunction

Online: 14 March 2024 (15:16:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.1118.v1

An Increase in HSF1 Expression Directs Human Mammary Epithelial Cells toward a Mesenchymal Phenotype

Natalia Vydra, Agnieszka Toma-Jonik, Patryk Janus, Katarzyna Mrowiec, Tomasz Stokowy, Magdalena Głowala-Kosińska, Damian Robert Sojka, Magdalena Olbryt, Wiesława Widłak

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: epithelial-to-mesenchymal transition; heat shock transcription factor 1; HSF1 inhibitor; human mammary epithelial cells

Online: 18 September 2023 (08:51:33 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202308.1410.v1

Altered Blood Molecular Markers of Cardiovascular Function in Rats After Intrauterine Hypoxia and Drug Therapy

Olena Popazova, Igor Belenichev, Oleh Yadlovskyi, Valentyn OKsenych, Aleksandr Kamyshnyi

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: prenatal hypoxia; cardioprotective; heat shock proteins; Angioli; L-arginine; Thiotriazoline; Mildronate; HSP70; HIF-1; eNOS

Online: 21 August 2023 (10:05:21 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202307.0711.v1

Rare Fatal Case of Purpura Fulminans with Acute Kidney Injury, Due to Pneumococcal Sepsis in Children, Associated with Multiorgan Failure

Maria Madalina Merisescu, Gheorghita Jugulete, Pavelescu Carmen, Monica Luminita Luminos

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Streptococcus pneumoniae; purpura fulminans; sepsis; shock; children; Acute Kidney Injury; multiple organ and system failures

Online: 11 July 2023 (10:41:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202302.0105.v2

IABP Versus Impella Support in Cardiogenic Shock: “In Silico” Study

Beatrice De Lazzari, Massimo Capoccia, Roberto Badagliacca, Selim Bozkurt, Claudio De Lazzari

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: IABP; Impella; Cardiogenic shock; Ventricular elastance; Heart failure; Lumped parameter model; Software simulation; Cardiovascular modelling.

Online: 15 February 2023 (02:47:13 CET)

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Preprint REVIEW | doi:10.20944/preprints202110.0168.v1

With or Without You: Co-chaperones Mediate Health and Disease by Modifying Chaperone Function and Protein Triage

Selin Altinok, Rebekah Sanchez-Hodge, Mariah Stewart, Kaitlan Smith, Jonathan C. Schisler

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: heat shock proteins; co-chaperones; protein quality control; protein folding; protein degradation; cardioprotection; neuroprotection; cancer

Online: 11 October 2021 (14:38:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0531.v1

HALO-RPD: In Searching for RNA-Binding Protein Targets in Plants

Anastasia Shamustakimova

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: A.thaliana; HaloTag; RNA-binding proteins; RNA pulldown assay; RNA-protein complexes; cold shock domain protein

Online: 23 July 2021 (09:32:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0464.v1

Macrophage-Derived Small Exosomes: Efficient Transmission and Cytotoxicity to Cancer Cells

Yanyin Lu, Takanori Eguchi, Chiharu Sogawa, Eman A. Taha, Manh Tien Tran, Toshiki Nara, Penggong Wei, Shiro Fukuoka, Takuya Miyawaki, Kuniaki Okamoto

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: tumor-associated macrophage; exosomes; extracellular vesicles; heat shock proteins; oral cancer; fluorescent labeling of exosomes

Online: 19 April 2021 (11:50:52 CEST)

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