Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin

Version 1 : Received: 25 April 2023 / Approved: 26 April 2023 / Online: 26 April 2023 (15:23:50 CEST)

A peer-reviewed article of this Preprint also exists.

Hasatsri, S.; Suthi, J.; Siriwut, N.; Charoensappakit, O. Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin. Pharmaceuticals 2023, 16, 685. Hasatsri, S.; Suthi, J.; Siriwut, N.; Charoensappakit, O. Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin. Pharmaceuticals 2023, 16, 685.

Abstract

Developing novel wound dressings containing medicinal plant extracts can have several potential benefits, including improving the therapeutic value of the dressings and reducing the cost of producing wound dressings. In this study, we prepared foam dressing containing Eclipta prostrata leaf extract and gelatin (Eclipta prostrata dressing). Chemical composition was verified using Fourier transform infrared spectroscopy (FTIR), and pore structure was obtained by scanning electron microscopy (SEM). The physical properties, including absorption and dehydration properties, were also evaluated. The chemical properties were measured to determine the pH environment after being submerged with Eclipta prostrata dressings. The results revealed that the Eclipta prostrata dressing had a pore structure with an appropriate pore size (313.25 ± 76.51 µm and 383.26 ± 64.45 µm for the Eclipta prostrata A and Eclipta prostrata B dressings, respectively). The Eclipta prostrata B dressing was more consistent porosity, resulting in a higher absorption capacity and faster dehydration rate. According to physical properties, the Eclipta prostrata B dressing is best used on low-exuding wounds. Furthermore, the Eclipta prostrata A and B dressings make a slightly acidic environment. Therefore, our foam dressing will not interfere wound healing process.

Keywords

Eclipta prostrata; gelatin; foam dressing; wound dressing; physical property; absorption; dehydration; pH environment

Subject

Chemistry and Materials Science, Biomaterials

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