Version 1
: Received: 21 July 2023 / Approved: 28 July 2023 / Online: 31 July 2023 (02:34:58 CEST)
How to cite:
Chen, Y.; Pan, Y.; Xu, S. The Effect of Cluster Nursing in ICU on Treatment Compliance and Intestinal Barrier Function in Patients with Refractory Septic Shock. Preprints2023, 2023072010. https://doi.org/10.20944/preprints202307.2010.v1
Chen, Y.; Pan, Y.; Xu, S. The Effect of Cluster Nursing in ICU on Treatment Compliance and Intestinal Barrier Function in Patients with Refractory Septic Shock. Preprints 2023, 2023072010. https://doi.org/10.20944/preprints202307.2010.v1
Chen, Y.; Pan, Y.; Xu, S. The Effect of Cluster Nursing in ICU on Treatment Compliance and Intestinal Barrier Function in Patients with Refractory Septic Shock. Preprints2023, 2023072010. https://doi.org/10.20944/preprints202307.2010.v1
APA Style
Chen, Y., Pan, Y., & Xu, S. (2023). <strong></strong>The Effect of Cluster Nursing in ICU on Treatment Compliance and Intestinal Barrier Function in Patients with Refractory Septic Shock. Preprints. https://doi.org/10.20944/preprints202307.2010.v1
Chicago/Turabian Style
Chen, Y., Yuefang Pan and Shunbo Xu. 2023 "<strong></strong>The Effect of Cluster Nursing in ICU on Treatment Compliance and Intestinal Barrier Function in Patients with Refractory Septic Shock" Preprints. https://doi.org/10.20944/preprints202307.2010.v1
Abstract
Objective: To evaluate the effect of care bundles on treatment compliance and intestinal barrier function in patients with refractory septic shock in the intensive care units (ICUs). Methods: In this retrospective study, the clinical data of 94 patients with refractory septic shock admitted to our hospital between June 2020 and April 2022 were collected. Patients with routine nursing were included in the routine group, and those with care bundles were assigned to the care bundles group, with 47 cases in each group. Outcome measures included nursing efficiency, treatment compliance, sequential organ failure assessment (SOFA) score, acute physiology and chronic health evaluation (APACHE II) score, intestinal barrier function, inflammation factor level, treatment outcome and complications. Results: Care bundles resulted in significantly higher nursing efficiency and treatment compliance versus routine care (P<0.05). Patients receiving care bundles showed significantly higher SOFA scores and APACHE II scores than those receiving routine care (P<0.05). Intestinal fatty-acid binding protein (I-FABP), diamine oxidase (DAO), lactate, endotoxin, and intestinal dysfunction scores in the care bundles group were significantly lower than those in the conventional group after treatment (P<0.05). Care bundles were associated with significantly lower levels of procalcitonin (PCT) and hypersensitive C-reactive protein (hsCRP), shorter time to symptom relief, ICU treatment time, and duration of mechanical ventilation, and lower 28-d morbidity and mortality versus routine care (P<0.05). Patients in the care bundles group had a significantly lower incidence of complications than those in the routine group (P<0.05). Conclusion: Care bundles effectively enhance treatment compliance, improve intestinal barrier function and treatment outcomes, reduce the inflammatory response, and decrease the risk of SOFA score, APACHE II score, and complications in patients with refractory septic shock.
Keywords
care bundles; ICU; refractory septic shock; treatment compliance; intestinal barrier function
Subject
Medicine and Pharmacology, Surgery
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
