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Preprint ARTICLE | doi:10.20944/preprints201712.0137.v1

Gimbutas’ Smile – An Archaeology Led, Archaeogenetic Model

Bob Kenyon

Subject: Arts And Humanities, Archaeology Keywords: Archaeology; Archaeogenetic Model; Neolithic; Chalcolithic; Bronze Age; Migration

Online: 19 December 2017 (15:49:22 CET)

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Migrations are much more important than currently recognised, for explaining important patterns observed in the European archaeology record – according to this archaeology led model. At a high level, they explain the introduction of different farming, monument building, the spread of metalworking and patterns of trade and exchange. This paper presents an archaeogenetic model based on a strategic review of the Neolithic and Chalcolithic archaeology of Europe, alongside a review of recently published ancient DNA data. The model is archaeology led. It takes archaeology themes and proposes migratory events to explain them. Ancient DNA data and further archaeology evidence is then used to test these proposed migrations- to reject or refine them. The model introduces a new and more strategic way of looking at archaeological cultures - that updates early 20th century approaches to studying archaeology cultures, and integrates with the detailed ‘post processual’ studies of the late 20th Century. The model consists of seven maps – each showing multiple migration events – with key evidence to support each migration map. It proposes a new category of a ‘Black Sea’ related population that makes a major genetic contribution to the Middle Neolithic of Europe. The proposed migrations provide an explanation for the observed patterns of archaeology, for example: • multiple Neolithic migrations that introduced, farming and metalworking into Europe; • a major ‘Black Sea’ related ‘Middle Neolithic’ migration that carried advanced knowledge of astronomy that can be recognised in a variety of types of monument from the Neolithic through to Bronze Age Europe; and, • migrations of related cultures (‘supercultures’) that explain patterns of trade and exchange in Bronze Age western Europe. The model also provides ancient DNA and archaeology based support for the key aspects of Childe’s ‘dawn of civilisation’ in Europe and Egypt and Gimbutas’ ‘Old Europe’ and “three waves of migration from the Steppe”.

Preprint ARTICLE | doi:10.20944/preprints201709.0016.v1

Responses of Soil Microbial Communities to Robinia Pseudoacacia Plantations of Different Ages in A Loess Area

Bingxue Zhang, Rumeng Zhao, Boyuan Bi, Fengpeng Han

Subject: Biology And Life Sciences, Forestry Keywords: soil; Robinia pseudoacacia; PLFA; stand age; microbial community

Online: 5 September 2017 (15:28:05 CEST)

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Phospholipid fatty acids (PLFAs) can be used as biomarkers for qualitative and quantitative analyses of soil microbial community diversity. In this study, we collected soil samples at 10-cm intervals to a depth of 1 m from Robinia pseudoacacia plantations of four different ages (10, 15, 25 and 40 years) in a loess area and analysed the soil microbial community structure by PLFA analysis. A total of 97 PLFAs were detected in soils of R. pseudoacacia plantations of different ages. The individual PLFA contents gradually decreased in the 0- to 40-cm soil layers, with little variation in the 40- to 100-cm soil layers. The individual PLFAs were similarly distributed in the soils of R. pseudoacacia plantations of different ages, and there was a clear variation with stand age and soil depth. The individual PLFA contents in the 0- to 20-cm soil layers were highest for the 25-year-old plantation, while those in the 20- to 40-cm soil layers were relatively high for the 25- and 40-year-old plantations; the 16:0 content was the highest among individual PLFAs. The total PLFA content and the PLFA contents of different microbial groups [bacteria, fungi, Gram-positive bacteria (G⁺), Gram-negative bacteria (G^-) and actinomycetes] initially increased before decreasing in the soils of R. pseudoacacia plantations with increasing stand age, whereas these contents gradually decreased with increasing soil depth; the highest PLFA contents was found in the 25-year-old plantation. The total PLFA content and the contents of fungal, G^- and actinomycete PLFAs in the soils of R. pseudoacacia plantations differed significantly among stands of different ages in the 0- to 10-cm, 10- to 20-cm and 30- to 40-cm soil layers, while no significant differences were found in the 20- to 30-cm soil layers; the G⁺ and bacterial PLFAs contents in each of the 0- to 40-cm soil layers were significantly different. The PLFA ratios between different microbial groups differed among the stands of different ages. The fungi/bacteria ratio showed a “decrease-increase-decrease” trend with stand age, while the G⁺/G^- ratio showed an “increase-decrease” trend. The saturated/monounsaturated PLFA ratio initially decreased before plateauing, while the opposite trend was observed for the cyclopropyl/precursor ratio. The PLFA contents of different microbial groups were ranked as follows: bacteria > G^- > G⁺ > actinomycetes > fungi. In the principle component analysis, 18:1ω9c, 10Me18:0, i17:0, a17:0, 18:1ω7c, 18:1ω5c and 18:0 made the greatest contribution to principal component 1, and a14:0, i14:0 3OH, i14:0, i14:1ω7c and 14:0 made the greatest contribution to principal component 2. In conclusion, soil nutrient status and other soil eco-environmental stress factors should be considered in 10- to 25-year-old (particularly ~15-year-old) plots for the management of R. pseudoacacia plantations to prevent forest soil degradation and improve forest stand quality, thereby achieving better soil and water conservation and environmental improvement in R. pseudoacacia plantations.

Preprint REVIEW | doi:10.20944/preprints202403.0700.v1

Waste Glycerol in the Biosynthesis of Liquid Fuels and Other Value-Added Products – a Review

Joanna Kazimierowicz, Marcin Dębowski, Marcin Zieliński, Sandra Mlonek, Jordi Cruz Sanchez

Subject: Engineering, Bioengineering Keywords: waste glycerol; glycerol for liquid fuels; glycerol for value-added products; valorisation of glycerol; bibliographic analysis

Online: 13 March 2024 (07:09:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1743.v1

Examine Website Defacement Dataset by Exploiting Some Classifiers’ Capabilities

Elrasheed Ismail Mohommoud Zayid, Ibrahim Isah, Yagoub Abbker Adam, Nadir Abdelrahman Ahmed Farah, Omar Abdullah Alshehri

Subject: Computer Science And Mathematics, Computer Science Keywords: prediction capabilities for website defacement; website defacement assessment; classification metrics for website hackticism; website defacement risks

Online: 27 October 2023 (05:27:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202008.0047.v2

Design Is How We Change the World! Can We Do It in Socially, Environmentally and Economically Acceptable Ways? Synthesizing Design Tools for This Utopian Concept

Kumaraswamy Ponnambalam, Abbas Seifi, Jamshid Mousavi

Subject: Social Sciences, Decision Sciences Keywords: design for society; design for sustainability; design under uncertainty; circular design; donut economics; life cycle analysis

Online: 5 August 2020 (04:50:02 CEST)

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Since the beginning, humans advanced their civilization by making better tools to improve their lives. Tools and products were designed for better living considering manufacturing issues, cost and time as predominant criteria. It has become clear that not considering environment and society, both at local/global levels, has now become a major impediment affecting living conditions on a large portion of the Earth and in many societies. Design methodologies should lead to creative solutions with consideration to engineering and economics for practicality but also to environmental and social constraints for sustainability. We propose a comprehensive design methodology based on multidisciplinary design to include the knowledge of humanities, environmentalists, science and engineering, and allowing for experts’ inputs from these areas to provide a holistic approach to engineering design . For example, experts in humanities are expected to interact with stakeholders to evaluate their value systems to provide guidance for the design. The methodology that we synthesize is new and combines (i) Societal level impacts at all scales, (ii) Environmental impacts and (iii) Engineering design with economic impacts, including uncertainty considerations. The proposed design methodology is called Social-Environmental-Economical-Engineering Framework (SEEEF). It can utilize concepts and tools such as Circular Design, Doughnut Economics, design based on environmental life cycle analysis, among others. SEEEF is quantity based and provides steps for evaluating any project or product in an objective manner and will help train engineers in design for sustainability. It also provides non-engineers with a significant role in design to increase their understanding of the hard constraints of engineering. Ultimately, SEEEF allows society to take an informed decision considering short/long term and local/global impacts of the design and the pertinent uncertainties.

Preprint ARTICLE | doi:10.20944/preprints202101.0412.v2

Raspberry PI for Kill Mosquitoes by Laser

Ildar Rakhmatulin

Subject: Biology And Life Sciences, Insect Science Keywords: laser for mosquito control; deep learning for mosquito control; insect detection; mosquito neutralization; pest detection; insect recognition; Raspberry Pi3; Raspberry Pi4; OpenCV for small object detect

Online: 2 August 2021 (16:44:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201802.0008.v1

Computational Information Geometry For Binary Classification of High-Dimensional Random Tensors

Gia-Thuy Pham, Rémy Boyer, Frank Nielsen

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: Optimal Bayesian detection, information geometry, minimal error probability, Chernoff/Bhattacharyya upper bound, large random tensor, Fisher information, large random sensing matrix

Online: 1 February 2018 (16:32:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202405.0124.v1

Evaluating Large Language Models for Structured Science Summarization in the Open Research Knowledge Graph

Vladyslav Nechakhin, Jennifer D’Souza, Steffen Eger

Subject: Information Systems, Computer Science And Mathematics Keywords: Large Language Models; Open Research Knowledge Graph; Structured Summarization

Online: 2 May 2024 (10:14:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1600.v1

GPTs or Grim Position Threats? The Potential Impacts of Large Language Models on Non-Managerial Jobs and Certifications in Cybersecurity

Raza Nowrozy

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: cybersecurity; skills; ChatGPT; workforce; large language model; generative AI

Online: 24 April 2024 (09:46:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1709.v1

LLM- Based Personalized Recommendations in Health

Boris A. Galitsky

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Large Language Models; personalization; recommendation; meta-prompts; abductive reasoning

Online: 29 February 2024 (12:51:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0703.v1

Comparative Small and Large Gap Rheometry for Cementitious Pastes

Mareike Thiedeitz, Thomas Kränkel

Subject: Engineering, Civil Engineering Keywords: Large gap rheometry; cementitious pastes; rheology; Reiner-Riwlin equation

Online: 13 February 2024 (03:36:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.0366.v1

Learning Analytics in the Era of Large Language Models

Elisabetta Mazzullo, Okan Bulut, Tarid Wongvorachan, Bin Tan

Subject: Social Sciences, Education Keywords: learning analytics; large language model; artificial intelligence; process data

Online: 4 August 2023 (07:23:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1723.v1

Truth-O-Meter: Collaborating with LLM in Fighting its Hallucinations

Boris A. Galitsky

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Large Language Model; hallucination; fact-checking; multiple inconsistent sources

Online: 25 July 2023 (13:09:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0636.v1

Large Eddy Simulation of Utility-Scale Wind Farm Sited over Complex Terrain

Jagdeep Singh, Jahrul Alam

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: Wind farm; complex-terrain; large eddy simulation; dispersive stress

Online: 11 July 2023 (03:09:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0904.v1

Wavelet Transforms and Machine Learning Methods for the Study of Turbulence

Jahrul M Alam

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: large eddy simulation; vortex stretching; subgrid model; isotropic turbulence

Online: 13 June 2023 (08:47:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202302.0420.v1

A Study on the Wide Range of Relative Humidity in Cirrus Clouds Using Large-Ensemble Parcel Model Simulations

Miao Zhao, Xiangjun Shi

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Cirrus clouds; Relative humidity; Parcel model; Large-ensemble simulations

Online: 24 February 2023 (07:15:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202109.0438.v1

Statistical Analysis of Dynamic Subgrid Modeling Approaches in Large Eddy Simulation

Mohammad Khalid Hossen, Asokan Mulayath Variyath, Jahrul M Alam

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: large eddy simulation; vortex stretching; subgrid model; isotropic turbulence

Online: 24 September 2021 (14:10:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0520.v1

Bafilomycin A1 Induces Caspase-Dependent Apoptosis and Inhibits Autophagy Flux in Diffuse Large B Cell Lymphoma

Fang Li, Ying Hu, Yizhou Hu, Ren Zhou, Zhengrong Mao

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: apoptosis; autophagy; bafilomycin A1; diffuse large B cell lymphoma

Online: 22 July 2021 (13:43:07 CEST)

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Preprint ESSAY | doi:10.20944/preprints202005.0320.v1

Huge Filaments as Regions of Space-Time Deformation

Irina Rozgacheva

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: cosmology; large scale structure; huge filaments; space-time deformation

Online: 20 May 2020 (06:52:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201910.0096.v1

Test of a Modified Rainfall-runoff Model in Large-scale River Basins

Spyros Giakoumakis, Dimitris Tigkas

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: Rainfall-runoff model; large-scale river basins; calibration; validation

Online: 9 October 2019 (10:16:32 CEST)

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Working Paper REVIEW

Global Learning for Sustainable Development: A Systematic Review

Birgitta Nordén, Helen Avery

Subject: Environmental And Earth Sciences, Environmental Science Keywords: global learning; global learning for sustainable development; South/North perspectives; sustainability; sustainable development; education for sustainable development

Online: 24 September 2020 (07:59:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.2143.v1

Predominant Maternal Risk Factors Increase the Prevalence of Caesarean Section Deliveries: A Cross-Sectional Study in a Reproductive-Aged Women Population

Eleni Pavlidou, Sousana K. Papadopoulou, Olga Alexatou, Evmorfia Psara, Dimitrios Papandreou, Maria Menzelou, Anastasia Sampani, Christina Tryfonos, Maria Spanoudaki, Gerasimos Tsourouflis, Gavriela Voulgaridou, Eleana Toli, Constantinos Giaginis

Subject: Public Health And Healthcare, Other Keywords: caesarean section; pre-pregnancy; overweigh; obesity; gestational weight gain; preterm birth; pregnancy complications; nutritional interventions; maternal risk factors

Online: 29 June 2023 (12:38:51 CEST)

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Background: There is an exponential increase in caesarean sections with epidemic proportions worldwide, which is considered as a serious public health issue that influences negatively both maternal and childhood health. Aims: This study aimed to evaluate the associations between pre-dominant maternal risk factors and the prevalence of caesarean section in a representative sample of women from Greece. Methods: This is a cross-sectional study conducted on 5182 healthy, re-productive-aged women from 11 geographically diverse Greek areas after applying specific inclu-sion and exclusion criteria. Statistical analysis was applied to evaluate the impact of maternal so-ciodemographic, anthropometric, lifestyle and perinatal factors in the risk of caesarean section de-liveries. Results: A high prevalence of 56.4% of caesarean section deliveries was recorded in the study population. The incidence of caesarean sections reached to 51.5% in private hospitals in which an increasing rate of 47.5% for planned caesarean sections were noticed. Older maternal age, pre-pregnancy overweight and obesity, excess gestational weight gain, high rates of preterm birth, better economic status, smoking habits, and private type of birth hospital were significantly related with enhanced risk of caesarean section, independently of multiple confounding factors. Conclu-sions: Our study revealed that caesarean section rates are continuously increase, while several maternal risk factors, including especially pre-pregnancy overweight/obesity and excess gestational weight gain, cumulatively raise its prevalence which further increase the risk for postnatal adverse outcomes for both the mothers and their children. Emergent public health policies and strategies should be promoted to confront the predominant maternal risk factors-related with caesarean sec-tion and inform future mothers how to be prevented from them by applying healthier nutritional and lifestyle habits and to select caesarean section only due to emergency medical reasons. Alarmingly enough, targeted nutritional intervention strategies are strongly recommended to ef-fectively reduce the prevalence of maternal pre-pregnancy overweight/obesity and the excess gestational weight gain, which in turn may minimize the risk of childhood overweight/obesity.

Preprint ARTICLE | doi:10.20944/preprints202107.0526.v1

Decreased Fatty Acid Transporter FABP1 and Increased Isoprostanes and Neuroprostanes in the Human Term Placenta: Implications for Inflammation and Birth Weight in Maternal Pre-Gestational Obesity

Livia Belcastro, Carolina S. Ferreira, Marcelle A. Saraiva, Daniela B. Mucci, Antonio Murgia, Carla Lai, Claire Vigor, Camille Oger, Jean-Marie Galano, Gabriela D.A. Pinto, Julian L. Griffin, Alexandre G. Torres, Thierry Durand, Graham J. Burton, Fátima L.C. Sardinha, Tatiana El-Bacha

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: maternal pre-gestational obesity; placenta; lipid metabolism; fatty acid transporter proteins; isoprostanoids; neuroprostanes; isoprostanes; docosahexaenoic acid; arachidonic acid

Online: 23 July 2021 (08:04:47 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202310.1363.v1

Novel Genetic Systemic Obstructive Microvascular Dysplasia

Andrea Frustaci, Romina Verardo, Rosario Cianci, Bruna Cerbelli, Maria Cecilia D'Asdia, Alessandro De Luca

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: New strategies for recovery of damaged functions

Online: 20 October 2023 (14:13:54 CEST)

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Preprint REVIEW | doi:10.20944/preprints202009.0086.v1

Molecular Pharming to Support Human Life on the Moon, Mars, and Beyond

Matthew J. McNulty, Yongao Xiong, Kevin Yates, Kalimuthu Karuppanan, Jacob M. Hilzinger, Aaron J. Berliner, Jesse Delzio, Adam P. Arkin, Nancy E. Lane, Somen Nandi, Karen A. McDonald

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: life support for space; plant molecular pharming

Online: 4 September 2020 (07:31:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201710.0050.v2

Impact of Genetic Polymorphism of Sulpha Transferase Genes (SULT1A) Genes on the Risk of Females with Breast Cancer in Jordan

Mona Bustami, Abdel-Ellah Al-Shudifat, Nagham Hussein, Mohannad Yacoub, Eiad Atwa, Israr Sabri, Rania Abu-Hamdah, Walid Abu-Rayyan, Tawfiq Arafat, Adnan Badran, Luay Abu-Qatouseh

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: polymorphism; risk for breast cancer; SULT1A allele

Online: 9 November 2018 (04:28:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1085.v1

Preparation and hydration properties of sodium silicate-activated municipal solid waste incineration bottom ash composite slag cementitious materials

Juan Deng, Guoxiong Wu, Yuchao Xia, Li Liu

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: MSWIBA, sodium silicate-activated, hydration properties, equivalent age modeling

Online: 17 April 2024 (08:06:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0025.v1

Analysis of the Evolution of Water Quality in Tanks according to the Connections and Operation Mode. Application to the most Suitable Design

Marta Hervás, Fernando Martínez-Alzamora, Pilar Conejos

Subject: Engineering, Civil Engineering Keywords: Simulation; water quality; water age; storage tanks; hydraulic networks

Online: 1 April 2024 (10:33:25 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202401.1332.v1

Influence of the Age of Free-Living Amoeba Cysts on Their Vertical Distribution in a Water Column

Zineb Fechtali-Moute, Sébastien Pomel

Subject: Biology And Life Sciences, Life Sciences Keywords: Free-Living Amoeba; cyst; age; water column; vertical distribution

Online: 17 January 2024 (13:38:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0040.v1

Discrete-time Survival Models with Neural Networks for Age-Period-Cohort Analysis of Credit Risk

Hao Wang, Anthony Graham Bellotti, Rong Qu, Ruibin Bai

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Credit risk; Survival model; Neural network; Age-Period-Cohort

Online: 3 January 2024 (03:53:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0166.v1

Knowledge Representation of Age-Related Diseases under Innate and Adaptative-Immunosenescence Valued Contexts

javier Burgos-Salcedo

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Immunosenescence; Knowledge representation; Formal concept Analysis; Age-related diseases

Online: 4 December 2023 (11:27:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1534.v1

Mitigating Age-related Bias in Predictive Policing Algorithms

Ahmed Saud Almasoud

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: predictive policing; algorithms; fairness; age bias; strategic subject list

Online: 24 November 2023 (02:42:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1581.v1

Could the Combination of eGFR and mGPS Facilitate the Differential Diagnosis of Age-Related Renal Decline from Diseases? A Large Study on the Population of Western Sicily

Miriam Carella, Annamaria Porreca, Cinzia Piazza, Francesco Gervasi, Daniele Magro, Marika Venezia, Raffaella Lo verso, Giuseppe Vitale, Anna giusy Agnello, Tommaso Aronica, Carmela Rita Balistreri

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: renal age-related decline; kidney disease (KD); eGFR; mGPS

Online: 25 October 2023 (08:35:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.1249.v1

The Relationship between Jealousy and Mate Retention Strategies in Romantic Relationships among Women during the COVID-19 Pandemic

Paulina Degiuli, Lea Andreis, Dario Vučenović

Subject: Social Sciences, Psychology Keywords: jealousy; partner retention strategies; romantic relationship; age; relationship length

Online: 20 October 2023 (08:06:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0658.v2

Assessment of Knowledge and Attitude of Reproductive Age Women towards Cervical Cancer Prevention in Selected Tertiary Institutions in Osun State, Nigeria

Oluwabunmi B. Erinsakin, Adeyemi O. Omoge, Oladunni Opeyemi, Idowu A. Olumakinde, Busayomi E. Folashayo, Michael N. Philip

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Knowledge; Attitude; Women of Reproductive Age; Cervical Cancer Prevention

Online: 17 October 2023 (11:47:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1322.v1

Age and Task Modulate Olfactory Sensitivity in the Florida Carpenter Ant Camponotus floridanus

Stephen T Ferguson, Isaac Bakis, Nicholas D Edwards, Laurence J Zwiebel

Subject: Biology And Life Sciences, Insect Science Keywords: hymenoptera; olfaction; odor coding; task allocation; age polyethism; aging

Online: 19 July 2023 (10:03:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0469.v1

Dynamical Analysis of an Age-Structured Sveir Model With Imperfect Vaccine

Yanshu Wang, Hailiang Zhang

Subject: Computer Science And Mathematics, Mathematical And Computational Biology Keywords: SVEIR model; latent age; imperfect vaccine; Lyapunov functions; stability

Online: 7 June 2023 (02:32:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0832.v1

Age of Onset Moderates the Association Between Total Antioxi-Dant Capacity and Cognitive Deficits in Patients With Drug-Naïve Schizophrenia

Jiaxin Li, Deyang Li, Junru Guo, Dongmei Wang, Xiangyang Zhang

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: schizophrenia; age of onset; TAOC; cognitive function; oxidative stress

Online: 24 April 2023 (06:22:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0152.v1

Eugenio Martelli, Matilde Zamboni, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe Massimo Sangiorgi, Mariangela Valentina Puci, Allegra Rosa Martelli, Teresa Messina, Paolo Frigatti, Maria Pia Borrelli, Carlo Ruotolo, Ilaria Ficarelli, Paolo Rubino, Francesco Pezzo, Luciano Carbonari, Andrea Angelini, Edoardo Galeazzi, Luca Calia Di Pinto, Franco Michelino Fiore, Armado Palmieri, Giorgio Ventoruzzo, Giulia Mazzitelli, Franco Ragni, Antonio Bozzani, Enzo Forliti, Claudio Castagno, Pietro Volpe, Mafalda Massara, Diego Moniaci, Elisa Pagliasso, Tania Peretti, Mauro Ferrari, Nicola Troisi, Pietro Modugno, Maurizio Maiorano, Umberto Marcello Bracale, Marco Panagrosso, Mario Monaco, Giovanni Giordano, Giuseppe Natalicchio, Antonella Biello, Giovanni Maria Celoria, Alessio Amico, Mauro Di Bartolo, Massimiliano Martelli, Roberta Munaó, Davide Razzano, Giovanni Colacchio, Francesco Bussetti, Gaetano Lanza, Antonio Cardini, Bartolomeo Di Benedetto, Mario De Laurentis, Maurizio Taurino, Pasqualino Sirignano, Pierluigi Cappiello, Andrea Esposito, Santi Trimarchi, Silvia Romagnoli, Andrea Padricelli, Giorgio Giudice, Adolfo Crinisio, Giovanni Di Nardo, Giuseppe Battaglia, Rosario Tringale, Salvatore De Vivo, Rita Compagna, Valerio Stefano Tolva, Ilenia D'Alessio, Ruggiero Curci, Simona Giovannetti, Giuseppe D'Arrigo, Giusi Basile, Dalmazio Frigerio, Gian Franco Veraldi, Luca Mezzetto, Arnaldo Ippoliti, Fabio Massimo Oddi, Alberto Maria Settembrini

Subject: Medicine And Pharmacology, Hematology Keywords: chronic limb-threatening ischemia; outcome; sex; age; limb salvage

Online: 8 December 2022 (09:39:30 CET)

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Preprint REVIEW | doi:10.20944/preprints202211.0350.v2

Recent Advances in Proteomic-based Approaches to Study Age-related Macular Degeneration: A Systematic Review

Laura García-Quintanilla, Lorena Rodríguez-Martínez, Enrique Bandín-Vilar, María Gil-Martinez, Miguel González-Barcia, Cristina Mondelo-García, Anxo Fernández-Ferreiro, Jesús Mateos

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Proteomics, Age-related macular degeneration, inflammation, biomarker, oxidative stress.

Online: 21 November 2022 (02:35:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202210.0278.v1

Association between Knowledge about Anemia, Food Consumption Behaviors, and Hematocrit Level among School-Age Children in Nakhon Si Thammarat Province, Thailand

Pastraporn Kaewpawong, Kiatkamjorn Kusol, Onuma Bunkarn, Sirigran Sutthisompohn

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: knowledge; food consumption behaviors; hematocrit level; school-age children

Online: 19 October 2022 (10:06:28 CEST)

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Anemia is a significant public health problem among children, especially school-age children because their body quickly produces red blood cells to provide sufficient blood volume with plasma expansion to maintain blood concentration. This research aimed to study the anemia situation, knowledge about anemia, food consumption behaviors, and the association between knowledge, food consumption behaviors, and hematocrit level among school-age children in primary school, in Thasala district, Nakhon Si Thammarat Province. This is a descriptive study among 408 students, Grades 4 to 6, aged 9-12 years. Research instruments included the demographic data of the children and their knowledge about anemia, food consumption behaviors, and hematocrit assessment. Data were analyzed using descriptive, Spearman’s rank correlation coefficient, and logistic regression statistics. The results revealed that 23.2% of the samples had anemia, whereas 22.22% had mild anemia and 0.98% had moderate anemia. The children knew about anemia, where the mean score was at a moderate level (Mean= 6.63; SD= 2.51) out of 10. The mean score on food consumption behaviors was in the moderate level (Mean= 17.49; SD= 3.68) out of 24. There were significantly positive correlations between the knowledge about anemia and the hematocrit level at a moderate level (r= 0.45, p< 0.001). Correlation analysis revealed moderate food consumption behaviors with the hematocrit level (r= 0.40, p< 0.001). When confirm with Logistic regression found that knowledge about anemia (OR = 9.15, 95% CI: 4.57-18.34), and food consumption behaviors (OR = 19.09, 95% CI: 9.71-37.53) were significantly associated with the hematocrit level. Conclusions: This study showed that knowledge and appropriate food consumption behaviors are associated with hematocrit levels. Enhancing knowledge about anemia and food consumption behaviors may be reduced the prevalence of anemia in school-age children. The health care providers in primary care should be encouraged children to have health education and eat sufficient food.

Preprint ARTICLE | doi:10.20944/preprints202206.0091.v1

Assessing the Effectiveness of Tobacco 21 Laws to Reduce Underage Access to Tobacco: Protocol for a Repeated Multi-Site Study

Mary Hrywna, Amanda Kong, Christopher Ackerman, Shawna Hudson, Cristine Delnevo

Subject: Public Health And Healthcare, Health Policy And Services Keywords: tobacco age of sale; tobacco policy; youth; young adults

Online: 7 June 2022 (03:44:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0367.v1

Differences in Citation Patterns across Areas, Article Types and Age Groups of Researchers

Marcelo Mendoza

Subject: Social Sciences, Library And Information Sciences Keywords: Citation patterns; Age groups of researchers; Types of publications.

Online: 17 August 2021 (15:09:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0434.v1

Clinical and Laboratory Characteristics of Kikuchi-Fujimoto Disease According to Age

Hye-Young Kim, Ha Young Jo, Seong Heon Kim

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Kikuchi-Fujimoto disease; histiocytic necrotizing lymphadenitis; prognosis; children; age

Online: 20 July 2021 (09:37:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0729.v1

Sergey Sudakov, Elena Alekseeva, Galina Nazarova, Valentina Bashkatova

Subject: Social Sciences, Psychology Keywords: age; behaviour; open field; physical activity; anxiety; Wistar rat.

Online: 30 June 2021 (10:57:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0536.v1

“What a Mobility-Limited World”: Design Requirements of an Age-Friendly Playable City

Liliana Vale Costa, Ana Isabel Veloso, Michael Loizou, Sylvester Arnab, Richard Tomlins, Arun Sukumar

Subject: Social Sciences, Urban Studies And Planning Keywords: playable city; age-friendly environments; games; mobility; active ageing

Online: 23 October 2018 (10:11:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201801.0111.v1

Applicability of Precision Medicine Approaches to Managing Hypertension in Rural Populations

Jacqueline R. Halladay, Kaitlin C. Lenhart, Kimberly Robasky, Wendell Jones, Wayne F. Homan, Doyle M. Cummings, Crystal W. Cené, Alan L. Hinderliter, Cassandra L. Miller, Katrina E. Donahue, Beverly A. Garcia, Thomas C. Keyserling, Alice S. Ammerman, Cam Patterson, Darren A. DeWalt, Larry F. Johnston, Monte S. Willis, Jonathan C. Schisler

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: hypertension; GWAS; precision medicine; rural population; SNP-age interaction

Online: 12 January 2018 (07:34:37 CET)

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Background: As part of the Heart Healthy Lenoir Project, we developed a practice level intervention to improve blood pressure control. The goal of this study was: i) determine if single nucleotide polymorphisms (SNPs) that associate with blood pressure variation, identified in large case-control studies, are applicable to blood pressure control in subjects from a rural population; ii) measure the association of these SNPs with subjects’ responsiveness to the hypertension intervention; and iii) identify other SNPs that may help understand patient-specific responses to an intervention. Methods and Results: We used a combination of candidate SNPs and genome-wide analyses to test associations with either baseline systolic blood pressure (SBP) or change in systolic blood pressure one year after the intervention in two genetically defined ancestral groups: African Americans (AA) or Caucasian Americans (CAU). Of the 48 candidate SNPs, 13 SNPs associated with baseline SBP in our study; however, one candidate SNP, rs592582, also associated with a change in SBP after one year. Using our study data, we identified 4 and 15 additional loci that associated with a change in SBP in the AA and CAU groups, respectively. Our analysis of gene-age interactions identified genotypes associated with SBP improvement within different age groups of our populations. Moreover, our integrative analysis identified AQP4-AS1 and PADI2 as genes whose expression levels may contribute to the pleiotropy of complex traits involved in cardiovascular health and blood pressure regulation in response to an intervention targeting hypertension. Conclusions: Identification of SNPs associated with the success of a hypertension treatment intervention suggests that genetic factors in combination with age may contribute to an individual’s success in lowering SBP. If these findings prove to be applicable to other populations, the use of this genetic variation in making patient-specific interventions may help providers with making decisions to improve patient outcomes. Further investigation is required to determine the role of this genetic variance with respect to the management of hypertension such that more precise treatment recommendations may be made in the future as part of personalized medicine.

Preprint ARTICLE | doi:10.20944/preprints201608.0133.v1

Calorie Restriction Supplemented with Fish Oil Ameliorates Abnormal Metabolic Status in Middle-Aged Obese Women: An Open-Label, Parallel-Arm, Controlled Trial

Fasty Arum Utami, Hsiu-Chuan Lee, Chien-Tien Su, Shih-Yi Huang

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: calorie restriction; PUFA; meal replacement; metabolic syndrome; middle age

Online: 13 August 2016 (03:39:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0178.v1

Raspberry Pi for Autonomous Home Farm Control

Ildar Rakhmatulin

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: RaspberryPI smart home farm; RaspberryPI for farm control; RaspberryPI for agriculture; RaspberryPI automation; Raspberry Pi & Internet of Things

Online: 7 July 2021 (11:19:50 CEST)

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Preprint DATASET | doi:10.20944/preprints202012.0047.v1

Dataset for Eye-Tracking Tasks

Ildar Rakhmatulin

Subject: Engineering, Automotive Engineering Keywords: eye tracking dataset; gaze tracking dataset; iris tracking dataset; CNN for eye-tracking; neural networks for eye-tracking

Online: 2 December 2020 (08:00:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1513.v1

Explaining Misinformation Detection Using Large Language Models

Vishnu S Pendyala, Eliot Christopher Hall

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Large Language Models; Natural Language Processing; Misinformation Containment; Explainable AI

Online: 23 April 2024 (12:05:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0768.v1

Towards Cognition-Aligned Visual Language Models via Zero-Shot Instance Retrieval

Teng Ma, Daniel Organisciak, Wenbao Ma, Yang Long

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Large Visual Language Models; Zero-Shot Instance Retrieval; Cognition-Alignment

Online: 13 March 2024 (07:29:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0795.v1

Finger Vein Identification Based on Large Kernel Convolution and Attention Mechanism

Meihui Li, Yufei Gong, Zhaohui Zheng

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: finger vein identification; CNN; large kernel; attention mechanism; dual-channel

Online: 10 January 2024 (08:20:36 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202312.1336.v1

Missense Variants in COL4A1/2 Are Associated with Cerebral Aneurysms: A Case Report and Literature Review

Masahiro Uemura, Natsuki Tanaka, Shoichiro Ando, Takehiko Yanagihara, Osamu Onodera

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: COL4A1; COL4A2; cerebral aneurysm; small vessel disease; large vessel abnormality

Online: 18 December 2023 (12:50:43 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1929.v1

Performance Scaling of Silicon after Moore’s Law

Ohm Rishabh Venkatachalam

Subject: Engineering, Electrical And Electronic Engineering Keywords: semiconductors; chips; hardware; large scale silicon die; chiplets; quantum hardware

Online: 30 November 2023 (10:33:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1638.v1

Using the ISO 9705 Room Corner Test for Smoke Toxicity Quantification of Oriented Strand Board

Gabrielle Peck

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: Smoke Toxicity; Large-Scale; Oriented Strand Board; ISO 9705; Flammability

Online: 28 November 2023 (01:40:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.0535.v1

A Generalised Series Model for LES of Premixed and Non-Premixed Turbulent Combustion

Weilin Zeng, Xujiang Wang, Kai Hong Luo, Konstantina Vogiatzaki, Salvador Navarro-Martinez

Subject: Engineering, Mechanical Engineering Keywords: Combustion modelling; Large Eddy Simulation; Non-premixed Combustion; Premixed Combustion

Online: 8 November 2023 (09:55:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1647.v1

A Chatbot that Learns One’s Preferences as the Next Step in Human Digital Twins: A Pilot Study using HyperCLOVA X, a Large Language Model

Joseph Yun, Joshua Lee, Yohan Yun, Stanley Yoon, Sang-Hoon Park, Sijung Yun

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: AI; HyperCLOVA X; Personality; Digital Twin; Large Language Model; Transformer

Online: 25 October 2023 (13:42:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.1487.v1

An Efficient Plug-and-Play Post-Training Pruning Strategy in Large Language Models

Yingtao Zhang, Haoli Bai, Haokun Lin, Jialin Zhao, Lu Hou, Carlo Vittorio Cannistraci

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: post-training pruning; combinatorial optimization; large language models; inference acceleration

Online: 24 October 2023 (07:51:13 CEST)

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Preprint REVIEW | doi:10.20944/preprints202307.1943.v1

Developing New Strategies for Relapsed/Refractory Diffuse Large B-Cell Lymphoma

EVA GONZALEZ-BARCA

Subject: Medicine And Pharmacology, Hematology Keywords: diffuse large B-cell lymphoma. relapsed/refractory; therapy; efficacy; toxicity

Online: 28 July 2023 (03:55:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0899.v1

CFD Model Verification and Aerodynamic Analysis in Large-Scaled Venlo Greenhouse Complex for Tomato Cultivation

Anthony Kintu Kibwika, Hyo-Jae Seo, Il–Hwan Seo

Subject: Engineering, Other Keywords: Grid independent test; Large-scale greenhouse; Natural ventilation; Ventilation efficiency

Online: 13 July 2023 (09:33:12 CEST)

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Preprint REVIEW | doi:10.20944/preprints202307.0229.v1

The Unmet Diagnostic and Treatment Needs in Large Cell Neuroendocrine Carcinoma of the Lung

Catalin Buium, Serban Negru, Diana Ionescu, Mircea Dediu

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: large cell; neuroendocrine; lung cancer; pathology; molecular subtypes; diagnosis; treatment

Online: 4 July 2023 (12:28:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1691.v1

Influence of Key Strata on the Evolution Law of Mining-induced Stress in the Working Face of Deep and Large-scale Mining

Jianlin Xie, Shan Ning, Weibing Zhu, Xiaozhen Wang, Tao Hou

Subject: Engineering, Mining And Mineral Processing Keywords: key strata; mining-induced stress; DOFS; 3DEC; large-scale mining

Online: 23 June 2023 (14:09:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0575.v1

Large Eddy Simulation Inflow Generation Using Reduced Length Scales for Low-Rise Buildings

Ava Shahrokhi, Julien Berthaut-Gerentes, Lin Ma, Derek Ingham, Mohamed Pourkashanian

Subject: Engineering, Mechanical Engineering Keywords: large eddy simulation; integral length scale; wind assessment; wind measurement

Online: 8 June 2023 (08:47:38 CEST)

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Preprint REVIEW | doi:10.20944/preprints202211.0471.v1

Provision of High-Quality Molasses Blocks to Improve Productivity and Address Greenhouse Gas Emissions from Smallholder Cattle and Buffalo in Developing Countries

Peter Andrew Windsor, Julian Hill

Subject: Biology And Life Sciences, Food Science And Technology Keywords: large ruminants, molasses blocks, greenhouse gas emissions, abatement, climate change

Online: 25 November 2022 (07:03:24 CET)

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Large ruminant production in developing countries is inefficient with low growth rates and likely high greenhouse gas emissions (GHGe) per unit of meat or milk produced. Trials conducted in Lao PDR from 2017-2020, studied ad-libitum supplementation for 12 weeks with 20kg high quality molasses nutrient blocks (MNB; Four Seasons Pty Ltd, Brisbane, Australia), that were either: non-medicated (NMB); fenbendazole-medicated (FMB5, Panacur100®, Coopers Australia, @ 5g/kg); triclabendazole-medicated (TMB5 or TMB10, Fasinex®, Novartis Australia, @ 5g/kg or @ 10g/kg, respectively); or formulated with urea (UMB8 or UMB10 @ 8% or 10% urea, respectively). Average daily gains (ADG) were determined for access to all MNB’s and compared with access to NMB’s, no supplementation, or previously determined free-grazing baseline ADG’s (55–84g in cattle; 92–106g in buffalo). ADGs were significantly improved following access to all MNBs for periods up to 12wks. ADGs following access to UMB8 or NMB were calculated for three age cohorts of cattle: young calves <8m (238-298g), growing cattle (143-214g) and lactating cows (179-191g). Modelling using IPCC Inventory software model V 2.69 of published data demonstrated a conservative net abatement of 350kg CO2e was achievable over a 200 day feeding period. An additional trial of Emissions control blocks (EMB’s, n = 200) distributed to farmers (n = 60) and two educational institutions, was conducted. Consumption rates (156g/day) and farmer and institutional acceptance of EMB’s were similar to published findings with other MNB’s, confirming all MNB’s and EMB’s improved animal productivity and body condition score, with healthier animals that were easier to manage. Modelling of changes in GHGe intensity identified an abatement of 470kg CO2e per EMB consumed, delivering a total project emissions abatement of 94t CO2e. Provision of MNBs and EMBs in smallholder large ruminant production systems is likely to achieve impressive abatement of GHGe due to improved efficiency of rumen fermentation and productivity.

Preprint ARTICLE | doi:10.20944/preprints202206.0379.v1

Porous TiO2/Carbon Dots Nanoflowers with Enhanced Surface Areas for Improving Photocatalytic Activity

Fengyan Song, Hao Sun, Hailong Ma, Hui Gao

Subject: Chemistry And Materials Science, Inorganic And Nuclear Chemistry Keywords: porous TiO2; hybrid TiO2/CDs; photocatalysts; photodegradation; large surface areas

Online: 28 June 2022 (06:02:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202112.0165.v1

One-Point Statistics Matter in Extended Cosmologies

Alex Gough, Cora Uhlemann

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: cosmology; theory; large scale structure of the Universe; analytical methods

Online: 10 December 2021 (07:31:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202108.0021.v1

A Note on Stokes Approximations to Leray Solutions of the Incompressible Navier-Stokes Equations in Rn

Joyce Cristina Rigelo, Janaina Pires Zingano, Paulo Ricardo Zingano

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Navier-Stokes equations, Stokes flows, Leray solutions, large time behavior

Online: 2 August 2021 (11:47:33 CEST)

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Preprint REVIEW | doi:10.20944/preprints201912.0128.v1

Comparative Analysis of Risk Management Techniques for Large-Scale Systems

Mehreen Sirshar, Aliya Shahid, Zoya Alam

Subject: Engineering, Control And Systems Engineering Keywords: large scale systems; risk assessment; risk management techniques; risk mitigation

Online: 10 December 2019 (07:14:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints201810.0637.v1

Untangling Cosmic Magnetic Fields: Faraday Tomography at MetreWavelengths with LOFAR

Shane O'Sullivan, Marcus Brüggen, Cameron Van Eck, Martin Hardcastle, Marijke Haverkorn, Timothy Shimwell, Cyril Tasse, Valentina Vacca, Cathy Horellou, George Heald

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: magnetic fields; Faraday tomography; large-scale structure; AGN; Milky Way

Online: 26 October 2018 (15:35:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201712.0131.v1

Is Equilibrium Modelling Outdated for Recent Challenges in River Management?

Arianna Varrani, Michael Nones

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: 1D modelling; large rivers; morphodynamic equilibrium; river concavity; bottom fining

Online: 19 December 2017 (07:15:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.0189.v1

The Global Burden of Type 2 Diabetes Attributable to Dietary Risks: Insights from the Global Burden of Disease Study 2019

Alina Ioana Forray, Mădălina Adina Coman, Ruxandra Simonescu-Colan, Andreea Isabela Mazga, Răzvan Mircea Cherecheș, Cristina Maria Borzan

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: type 2 diabetes mellitus; Global Burden of Disease Study; dietary risk factors; Age- Standardized Mortality Rate; Age-Standardized DALY Rate; Socio-Demographic Index

Online: 4 October 2023 (04:55:59 CEST)

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Preprint REVIEW | doi:10.20944/preprints202401.0937.v1

Fostering a Whole Institution Approach to Sustainability Through Systems Thinking: An Analysis of the State-of-the-Art in Sustainability Integration in Higher Education Institutions

Odysseas Christou, Dimitra B. Manou, Stefano Armenia, Eduarfo Franco, Anastasia Blouchoutzi, Iason Papathanasiou

Subject: Social Sciences, Education Keywords: systems thinking; whole institution approach; education for sustainable development (ESD); education for sustainability (EfS); higher education; sustainable development; sustainability

Online: 11 January 2024 (13:08:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.0774.v1

Junxia Li, Zhenguo Wang, Liujia Wang, Xiayuan Wang, Dong He, Xinming Duan, Chunxiang Zhang, Youshe Ren, Chunhe Yang

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: cashmere goat; cashmere production; secondary hair follicle; age; oxidative stress

Online: 11 April 2024 (10:12:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1497.v1

Ethnic Representation Matters: Investigating Bias in Facial Age Prediction Models

Nenad Panić, Marina Marjanović, Timea Bezdan

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Facial recognition; Age prediction; Convolutional Neural Network (CNN); Ethnicity bias

Online: 26 March 2024 (08:15:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0998.v1

Development and Implementation of Virtual Reality Application: Age-Friendly Health System Scenario

Sweta Tewary, Oksana Shnayder, Marie Dezine, Naushira Pandya

Subject: Public Health And Healthcare, Primary Health Care Keywords: virtual reality; age friendly health systems; medical education; older adults

Online: 19 February 2024 (15:45:44 CET)

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INTRODUCTION: With an increase in the aging population, the application of evidence-based practice in geriatric education can strengthen knowledge, skills, and clinical experience for healthcare students caring for older adults. Age Friendly Health Systems (AFHS) is one of the frameworks founded on providing evidence-based and low-risk care centered on what matters most to older adults, their families, and caregivers. Virtual Reality (VR) platforms are gaining popularity due to their ability to provide an immersive, hands-on learning experience resembling an actual medical practice or care setting. Immersive learning enhances students’ sensory perceptions, promoting an innovative and engaging way of acquiring concepts that are difficult to teach in real life. This study aimed to design, develop, implement, and evaluate a case-based training module highlighting AFHS and educating medical students on the 4Ms approach in geriatric care (What Matters, Medication, Mentation, and Mobility). METHODOLOGY: The project was a feasibility study completed in two phases. Phase one included planning and development of a case-based scenario incorporating 4Ms of AFHS. Phase two included implementing and evaluating the VR training module into the geriatric curriculum for medical students. RESULTS: The final VR case displays a hospital and post-acute setting where an elderly patient is admitted for a hip fracture. Students learn how to triage and treat patients from admission to discharge while demonstrating their knowledge of AFHS. Approximately 10% of students completed the evaluation survey, and preliminary results indicate significant knowledge change in pre-post scenario-based training on AFHS. CONCLUSION: The VR education platform and embedded scenario promise an innovative adaptation of technology in learning the concepts of the 4Ms of AFHS. However, future studies should explore VR education with clinical assessment evaluation to ensure competence in providing Age-Friendly care.

Preprint REVIEW | doi:10.20944/preprints202402.1022.v1

The Value of Autopsy in the Modern Age: Discrepancy between Clinical and Autopsy Diagnoses

Cecilia Salzillo, Roberta Basile, Gerardo Cazzato, Giuseppe Ingravallo, Andrea Marzullo

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: hospital autopsy; modern age; clinical diagnosis; autopsy diagnosis; Public Health

Online: 19 February 2024 (08:22:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1799.v1

Suboptimal Nutritional Status of School-Age Children in Addis Ababa: Evidence from the Analysis of Sociodemographic, Environmental, and Behavioral Factors

Yimer Mihretie Mihretie, Abebe Ayelign, Tadesse Alemu Zerfu

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: ; Addis Ababa; dietary factors; nutritional status; school-age children

Online: 25 January 2024 (09:53:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0350.v1

Human Age Estimation from Face Images with Deep Convolutional Neural Networks Using Transfer Learning

Gilbert George, Chandrashekhar Uppin, Usman Abubakar Bello

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Convolution neural network; Deep Learning; Facial Age; Regression; Transfer learning

Online: 4 January 2024 (07:41:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1081.v1

Splenic Stiffness Measured by 3-Tesla Magnetic Resonance Elastography Is Correlated with Age in Healthy Individuals

Süheyl Poçan, Levent Karakaş

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: 3 tesla magnetic resonance; age, healty volunteers; elastography; splenic stiffness

Online: 17 October 2023 (11:20:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.1069.v1

Splenic Stiffness Measured by 3-Tesla Magnetic Resonance Elastography Is Correlated with Age in Healthy Individuals

Süheyl Poçan, Levent Karakaş

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: 3 tesla magnetic resonance; age; healty volunteers; elastography; splenic stiffness

Online: 17 October 2023 (11:11:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0861.v1

Pattern of Presentation and Risk Factor Prediction of Acute Myocardial Infarction in Kosovo

Afrim Poniku, Arlind Batalli, Dua Shita, Zarife Rexhaj, Arlind Ferati, Rita Leka, Artan Bajraktari, Genc Abdyli, Edmond Haliti, Pranvera Ibrahimi, Shpend Elezi, Faik Shatri, Ibadete Bytyçi, Michael Henein, Gani Bajraktari

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Myocardial infarction; risk factors; smoking; diabetes; arterial hypertension; age; gender

Online: 14 September 2023 (02:34:12 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.0670.v1

Precision and Accuracy of Radiological Bone Age Assessment in Children among Ethnical Groups

Sebastián Eustaquio Martín Pérez, Isidro Miguel Martín Pérez, Jesús Vega González, Ruth Molina Suárez, Coromoto León Hernández, Fidel Rodríguez Hernández, Mario Ulises Herrera Perez

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: diagnostic imaging; radiography; age determination by skeleton; racial group; children

Online: 11 September 2023 (11:11:23 CEST)

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Introduction: Determination of radiological bone age (BA) is a diagnostic method that consists of estimating chronological age (CA) from the bone maturation of children. Although environmental and hormonal factors can interfere with bone ossification, the process is essentially dependent on ancestral inheritance. These ethnic backgrounds are not usually considered, which can lead to biased interpretations and inadequate decision-making by pediatricians or forensic experts. The objective of this study was to determine the precision and accuracy of these radiological procedures among different ethnic groups. Methods: A qualitative systematic review carried out following MOOSE statement and previously registered in the International Prospective Registry of Systematic Reviews PROSPERO (CRD42023449512). Search was performed in MEDLINE (PubMed) (n=561), Cochrane Library (n=261), CINAHL (n=103), Web of Science (WOS) (n=181) and public institutional repositories (n=37) from inception to 31st December 2022 using Mesh as “Diagnostic Techniques and Procedures”, “Diagnostic imaging”, “Radiography”, “Age Determination by Skeleton” and free terms combining with booleans “AND” and “OR”. PEDro scale, and Risk of Bias in non-randomized Studies of Exposure (ROBINS-E) were used to assess methodological quality and risk of bias of included studies respectively. Results: 51 articles (n=19,531) were included according to the inclusion criteria previously established. There was a good to moderate methodological quality and a high to very high risk of bias. Skeletal methods for determining BA were precised in terms of intra-observer and inter-observer reliability in all ethnic groups. Regarding to accuracy of Skeletal methods in Caucasians and Hispanic children, GPA was accurate at all ages, but in youths, TW3 RUS could be a consistent alternative. In Asian and Arab, GPA and TW3 overestimated BA in adolescents near adulthood. In African youths, GPA overestimated BA while TW3 was more accurate in estimating CA. Dental and Cervical radiographic methods are equally precise but lesser accurate than Skeletal BA determination. Conclusion: Skeletal radiographic methods GPA and TW3 are both precise for BA determination among all ethnical groups, but their accuracy in estimating CA can be altered by racial bias.

Preprint ARTICLE | doi:10.20944/preprints202306.0653.v1

Determinants of Child Nutritional Status among Scheduled Tribes in West Bengal

Manabindra Barman, Dr. Indrajit Roy Chowdhury

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Scheduled tribe; Children; Nutritional status; Under 5years age; Determinant factors

Online: 9 June 2023 (03:04:37 CEST)

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Malnutrition is the main cause of child mortality in developing nations, especially in Sub-Saharan Africa and South Asian countries. This undernutrition status is predominantly higher among primitive tribal (ST) children under 5 years of age. The nutritional status of tribal children is a serious concern in India. For this, there should be intends to examine the prevalence and determinants of primitive tribal children's nutritional status. To investigate the effect of household, child’s & maternal characteristics on biological children under 5 years of age. The study aims to find out the association between some selected determinants on scheduled tribe child’s nutritional status. The study used some selected variable of scheduled tribe mothers, household characteristics and their children anthropometric indices from DHS datasets of India, which was published by the NFHS datasets of India. In this study People datasets and Children (Under 5 years of age) of interviewed women file datasets of NFHS-IV & V is taken. The datasets of West Bengal, ST mothers, and their child into consideration as per the research interest. Then to analyze the determinants of ST children (U5 age) nutritional status, some determinant factors are taken from mothers, children and household characteristics. Children’s stunting, wasting and underweight as dependent variable and the mothers, child’s and household’s characteristics as independent variable. The statistical analysis was done by using Pearson Chi square test used to analyze the association between dependent and independent variables. The study results shows that the mother’s educational status, child’s age, birth order, size of child at birth, type of residence had significant associations with stunting. Mother's anemia status and mother age had significant associations with wasting. Mother education, currently breastfeeding, child age, sex of the child, birth order, size of child at birth, type of residence, wealth, toilet facility, and cooking fuel shows a significant association with underweight. The results found that many determinant factors had a significant role among ST children's (U5 age) nutritional status. Thus, the findings will help to achieve tentative resource allocation, and utilization through various programs and policies to improve the ST children (U5 age) nutritional status. There is a need to take a multisectoral and multidimensional approach to develop for those primitive tribal children.

Preprint ARTICLE | doi:10.20944/preprints202305.1011.v1

Prevalence of Vitamin B₁₂ and Folate Deficiencies in Indian Children and Adolescents

Tattari Shalini, Raghu Pullakhandam, Santu Ghosh, Bharati Kulkarni, Hemalatha Rajkumar, Harshpal S Sachdev, Anura V Kurpad, Geereddy Bhanuprakash Reddy

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Vitamin B12 deficiency; Folate deficiency; School-age children; Adolescents; CNNS

Online: 15 May 2023 (09:45:12 CEST)

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Deficiencies of vitamin B12 (B12) and folate (FA) are of particular interest due to their pleiotropic role in 1-carbon metabolism. In addition to adverse birth outcomes, deficiencies of B12 and FA, or an imbalance in FA/B12 status, are linked to metabolic disorders. Indian diets that are predominantly plant food-based could be deficient in these vitamins, but there are no national estimates of the prevalence of B12 and FA deficiency in Indian children and adolescents, nor of their associations with age, sex, and growth indicators. The recent Comprehensive National Nutrition Survey (CNNS-2016-18) provided estimates of the prevalence of B12 and FA deficiency at the national and state level among preschool (1-4y: 9,976 and 11,004 children respectively), school-age children (5-9y: 12,156 and 14,125) and adolescents (10-19y: 11,748 and 13,621). Serum B12 and erythrocyte FA were measured by the direct chemiluminescence method and their deficiency was defined using WHO cut-offs. The prevalence of B12 and FA deficiency was high among adolescents (31.0%, CI: 28.7-33.5 and 35.6%, CI: 33.1-8.2), compared to school-age (17.3%, CI: 15.4-19.3 and 27.6%, CI: 25.5-29.9) and preschool children (13.8%, CI: 11.7-16.2 and 22.8%, CI: 20.5-25.2, respectively). The prevalence of both B12 and FA deficiency was significantly higher by 8 and 5% points respectively, in adolescent boys compared to girls. The prevalence of B12 deficiency was higher in moderately stunted school children (by 18.9% points) than in normal children, but no such difference was observed for FA deficiency. There was wide regional variation in the prevalence of B12 and FA deficiency, but no rural-urban differences were observed across all age groups. The national prevalence of B12 deficiency among preschool or school-age children was <20% (the cut-off that indicates a public health problem). However, FA deficiency in these age groups and both FA and B12 deficiencies in adolescents were >20%, which warrants further investigation.

Preprint ARTICLE | doi:10.20944/preprints202305.0165.v1

Computed Tomographic Features of Thymus Gland in Dogs: Correlation with Age, Gender, Breed and Body Fat Content

Mohammad Molazem, Sarang Soroori, Alireza Bahonar, Saghar Karimi

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Computed tomography, Thymus Gland, Dog, Age, Gender, Breed, Body Fat

Online: 4 May 2023 (02:59:54 CEST)

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: Background: The thymus gland is the first lymphoid organ formed to regulate a newborn's immunity. It reaches its maximum size during puberty, after which it undergoes an atrophic procedure called involution, but its ability to grow again in response to some stresses, such as infections, neoplasia, surgeries, chemotherapy, and radiotherapy is maintained. There is not any comprehensive study on computed tomographic features of thymus gland in dogs. So, the goal of the present study is to achieve some information about thymus gland using computed tomography as a non-invasive method. Methods: One hundred and fifty dogs classified in 5 age groups and 2 breed groups were entered to this study and the thymus gland was evaluated using 2-slice computed tomography machine. The inclusion criteria for the present study were having normal complete blood count, plain and post-contrast CT scan examination of thoracic region and no history of neoplasia, chemotherapy or radiotherapy. The visibility, density, enhancement, grade, size, volume, shape, borders and lateralization of the thymus were evaluated and statistical analysis were performed. The effect of obesity on thymic grade and volume were also investigated. Results: The visibility, density, dorsal length, volume and grade decreased with increasing age. The thymic shape and lateralization were mostly wedge-shaped and left sided respectively. The borders became concave with aging and increasing body fat content caused to increase fatty degeneration of thymus. Conclusions: Declining of thymic density, grade, size and volume with aging was related to thymic involution and fatty degeneration was accelerated by increasing body fat content. Females and Males were different only in thymic shape and small and large breeds were different only in thymic volume. The thymus was visible in some geriatric dogs with no underlying disease. We hope that the present work can be used by radiologists in reading thoracic computed tomography but investigation of thymic characteristics in dogs with neoplasia and history of chemotherapy, radiotherapy and thoracic surgeries can complete this study.

Preprint ARTICLE | doi:10.20944/preprints202205.0409.v1

Are There Sex Differences in Self-Reported Childhood Maltreatment in Major Depressive and Bipolar Disorders? A Retrospective Cross-Sectional Study

Daniela Caldirola, Tatiana Torti, Francesco Cuniberti, Silvia Daccò, Alessandra Alciati, Koen Schruers, Giovanni Martinotti, Domenico De Berardis, Giampaolo Perna

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: childhood trauma; major depressive disorder; bipolar disorder; sex difference; age

Online: 31 May 2022 (03:39:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202202.0192.v1

Inequalities in Temporal Effects on Cervical Cancer Mortality in States in Different Geographic Regions of Brazil: An Ecological Study

Karina Cardoso Meira, Carinne Magnago, Angelo Braga Mendonça, Stephane Fernanda Soares Duarte, Pedro Henrique Oliveira de Freitas, Juliano dos Santos, Dyego Leando Bezerra de Souza, Taynãna César Simões

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: uterine cervical neoplasms; mortality; age-period-cohort analysis; forecasting; Brazil

Online: 16 February 2022 (05:03:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202111.0506.v1

A Retrospective Cohort Study of the Clinical Features, Pathological Characteristics, and Molecular Classification in Reproductive Age Patients with Endometrial Cancer who Experienced Unsuccessful Fertility-sparing Treatment

Tong Yu, Xi-Wen Zhang, Ping-Li Sun, Abdulkarim Mohamed Farah, Yan Jia

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: endometrial cancer; fertility-sparing management; molecular classification; reproductive age; pregnancy

Online: 26 November 2021 (12:42:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0446.v1

Non-Modifiable Risk Factors (Age and Sex), Stroke Types, and Outcomes in Rivers State, Nigeria: A Retrospective Hospital-Based Study

Osborne Ikechuckwu Osuegbu, Foluke Olukemi Adeniji, Golden Chukwuemaka Owhonda, Rogers Bariture Kanee, M Alblihed, Gaber El-Saber Batiha, Eric Osamudiamwen Aigbogun

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Age; Sex; Stroke Types; Outcomes; SEM; Tertiary Hospitals; Rivers State

Online: 20 July 2021 (11:45:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0696.v1

Revealed Preferences of Fourth Graders When Requesting Face-to-Face Help While Doing Math Exercises Online

Roberto Araya, Raúl Gormaz

Subject: Business, Economics And Management, Accounting And Taxation Keywords: Help Seeking; Same-age Peer Tutoring; Revealed Preferences; Data analytics

Online: 29 June 2021 (11:36:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0392.v1

Prevalence of Controlled Systemic Hypertension and Its Associated Risk Factors among Hypertensive Patients at Mbeya Zonal Referral Hospital, Tanzania.

Samson Peter Mvandal, Victor Jastin Mwinuka

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Age; adherence; anti-hypertensive; Controlled hypertension; clinic; hypertension; Prevalence; Systemic

Online: 17 May 2021 (15:57:01 CEST)

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Working Paper REVIEW

A Systematic Review of Neuroimaging and Acute Cannabis Exposure in Age-of-Risk for Psychosis

Lani Cupo, Eric Plitman, Elisa Guma, M Mallar Chakravarty

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: systematic review; cannabis; neuroimaging; age-of-onset psychosis; psychosis; schizophrenia

Online: 14 May 2021 (09:58:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0589.v1

Compaction Model for Shale in Differences of Geological Ages Using A 3D Empirical Relationship in Northeastern Thailand

Avirut Puttiwongrak, Syukratun Nufus, Chaiyaphruk Bunprasert, Pham Huy Giao, Sakanann Vann, Thongchai Suteerasak, Nophea Sasaki

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Shale compaction; Geological age; Thailand shale; Compaction model; Standard curve

Online: 21 April 2021 (16:50:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202012.0478.v1

Quality of Life: Changes in Self Perception in People with DS who Participate in Laliga Genuine Santander. Self Reports and External Reports

Rocío Camacho, Cristina Castejón-Riber, Francisco Requena, Julio Camacho, Arturo Gallego, Roberto Espejo, Amaranta De Miguel-Rubio, Begoña M. Escribano, Estrella I. Agüera

Subject: Social Sciences, Psychology Keywords: Down's Syndrome; perception; quality of life; sport; age; gender; scale

Online: 18 December 2020 (16:17:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0090.v1

Tapering, Tree Rings and Biomass Production of Pinus roxburghii (Sarg.): A Dendrochronological Study

Hari Prasad Pandey, Narayan Prasad Pokhrel

Subject: Biology And Life Sciences, Forestry Keywords: age; coring sample; forest productivity; Nepal; P. roxburghii; stand structure

Online: 4 September 2020 (08:08:30 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints202005.0005.v1

Age-Adaptive and Gender-Balanced Social Interventions Might Be Stepping Stones to the Next ‘New Normal’ in COVID-19 Outbreak

Carlo Vittorio Cannistraci, Ilaria Capua

Subject: Biology And Life Sciences, Virology Keywords: social intervention; COVID-19; health policy; public health; age; gender

Online: 2 May 2020 (12:04:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202002.0051.v3

Bulk and Single-Cell Transcriptomics Identify Tobacco-Use Disparity in Lung Gene Expression of ACE2, the Receptor of 2019-nCov

Guoshuai Cai

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Wuhan 2019-nCov; ACE2; expression; susceptibility; race; age; gender; smoking; single cell

Online: 2 March 2020 (01:38:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints201912.0380.v1

Physical Activity in Elderly Kidney Transplant Patients with Multiple Renal Arteries

Armando Calogero, Caterina Sagnelli, Gaia Peluso, Antonello Sica, Maria Candida, Silvia Campanile, Gianluca Minieri, Paola Incollingo, Massimiliano Creta, Luigi Pelosio, Vincenzo Tammaro, Alessandro Scotti, Akbar Jamshidi, Marcello Caggiano, Evangelista Sagnelli, Concetta Anna Dodaro, Nicola Carlomagno, Michele Santangelo

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: physical activity; kidney transplantation; elder age; vascular anomalies; marginal kidneys

Online: 29 December 2019 (11:06:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints201908.0236.v1

Growth Opportunities and Earnings Quality from Emerging Economies

Jerry Danjuma kwarbai, Rufus Ishola Akintoye, Festus Fola Adegbie, Apollos Nwabuisi Nwaobia

Subject: Business, Economics And Management, Accounting And Taxation Keywords: earnings quality; growth opportunities; discretionary accruals; corporate age; corporate size

Online: 23 August 2019 (04:40:37 CEST)

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