Version 1
: Received: 16 October 2023 / Approved: 17 October 2023 / Online: 17 October 2023 (11:20:56 CEST)
How to cite:
Poçan, S.; Karakaş, L. Splenic Stiffness Measured by 3-Tesla Magnetic Resonance Elastography Is Correlated with Age in Healthy Individuals. Preprints2023, 2023101081. https://doi.org/10.20944/preprints202310.1081.v1
Poçan, S.; Karakaş, L. Splenic Stiffness Measured by 3-Tesla Magnetic Resonance Elastography Is Correlated with Age in Healthy Individuals. Preprints 2023, 2023101081. https://doi.org/10.20944/preprints202310.1081.v1
Poçan, S.; Karakaş, L. Splenic Stiffness Measured by 3-Tesla Magnetic Resonance Elastography Is Correlated with Age in Healthy Individuals. Preprints2023, 2023101081. https://doi.org/10.20944/preprints202310.1081.v1
APA Style
Poçan, S., & Karakaş, L. (2023). Splenic Stiffness Measured by 3-Tesla Magnetic Resonance Elastography Is Correlated with Age in Healthy Individuals. Preprints. https://doi.org/10.20944/preprints202310.1081.v1
Chicago/Turabian Style
Poçan, S. and Levent Karakaş. 2023 "Splenic Stiffness Measured by 3-Tesla Magnetic Resonance Elastography Is Correlated with Age in Healthy Individuals" Preprints. https://doi.org/10.20944/preprints202310.1081.v1
Abstract
Background: We aimed to determine the splenic stiffness (SS) values in healthy individuals as measured by 3 Tesla magnetic resonance elastography (3T MRE) and to investigate the possible effects of parameters such as age, sex, spleen volume, diameter, and parenchyma thickness on SS.Methods: A total of 54 healthy volunteers were included in this cross-sectional study. Participants' age and sex information were recorded, in addition to spleen craniocaudal and anteroposterior diameter, cortical thickness, spleen volume, and SS, which were measured using 3T magnetic resonance imaging and MRE. Results: Twenty-nine male and 25 female subjects with a mean age of 54.78±15.40 years were included in the study. Mean cradiocaudal diameter was 10.46±1.16 cm, anteroposterior diameter was 9.88±1.29 cm, parenchyma thickness was 4.08±0.67 cm, SS was 3721.94±709.69 Pascal (Pa), and median spleen volume was 292.54 (239.40-311.00) cm3. A significant positive correlation was observed between age and SS (r=0.779, p<0.001). The SS values were not associated with sex, craniocaudal diameter, anteroposterior diameter, parenchymal thickness, or volume.Conclusion:Age should be considered when using SS in the diagnosis and staging of relevant diseases such as portal hypertension and esophageal varices. Our results should be confirmed by future studies using 3T MRE in larger populations.
Keywords
3 tesla magnetic resonance; age, healty volunteers; elastography; splenic stiffness
Subject
Medicine and Pharmacology, Medicine and Pharmacology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
