ARTICLE
|
doi:10.20944/preprints201908.0131.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
pharmacogenomics; immune checkpoint blockade; immunotherapy; drug response prediction; algorithm; mathematical model; precision medicine; personalized medicine
Online: 11 August 2019 (14:51:14 CEST)
REVIEW
|
doi:10.20944/preprints202001.0324.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
natural products; sirtuin; drug discovery; epigenetics; structure–activity relationship
Online: 27 January 2020 (09:21:29 CET)
REVIEW
|
doi:10.20944/preprints202201.0117.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
G protein-coupled receptor; mouse models; skin cancer; UVR; drug; network
Online: 10 January 2022 (13:41:08 CET)
HYPOTHESIS
|
doi:10.20944/preprints202202.0032.v1
Subject:
Engineering,
Bioengineering
Keywords:
Organ-on-a-Chip (OoC); Micro-physiological systems (MPS); survey; usability; limitations; disease models; drug testing
Online: 2 February 2022 (12:20:19 CET)
REVIEW
|
doi:10.20944/preprints201910.0296.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
nasal delivery; glioblastoma multiforme; drug delivery; nanoparticles; nose-to-brain delivery; pre-clinical studies; clinical evaluation
Online: 27 October 2019 (09:36:27 CET)
REVIEW
|
doi:10.20944/preprints201810.0577.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
myeloma; daratumumab; elotuzumab; isatuximab; CD38; JNJ- 63723283; denosumab; checkpoint inhibitors; BCMA; bispecific T-cell engager; antibody-drug conjugates
Online: 24 October 2018 (12:11:23 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0329.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Machine Learning; Deep Learning; Molecular Modeling; Virtual Screening; Drug Discovery
Online: 18 November 2021 (13:59:09 CET)
ARTICLE
|
doi:10.20944/preprints202002.0009.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
target identification; drug affinity responsive target stability (DARTS); mass spectrometry imaging (MSI); voacangine; curcumin; natural products
Online: 3 February 2020 (04:36:54 CET)
ARTICLE
|
doi:10.20944/preprints201810.0697.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
glioma; glioblastoma; pre-clinical drug development; 3D culture systems; radiotherapy
Online: 30 October 2018 (03:38:28 CET)
ARTICLE
|
doi:10.20944/preprints202104.0483.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Network embedding; multiplex-heterogeneous network; multi-layer network; drug repositioning; graph representation learning
Online: 19 April 2021 (13:21:02 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0588.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Trazodone; drug design; dissolution; crystal structure; solid-state NMR (SSNMR) spectroscopy; GIPAW calculation
Online: 23 December 2020 (13:42:36 CET)
REVIEW
|
doi:10.20944/preprints202007.0478.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Bioinformatics; Drug Design; Small Organic Molecule; Target identification; Web-based Server
Online: 25 July 2020 (17:50:30 CEST)
ARTICLE
|
doi:10.20944/preprints202207.0004.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
SARS-CoV-2; COVID-19; drug repurposing; artificial intelligence; target-target similarity network; drug-target interaction network
Online: 1 July 2022 (05:33:16 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0275.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Cloud infrastructure; Spark; Molecular Dynamics simulations; Drug design.
Online: 16 September 2021 (11:02:38 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0490.v1
Subject:
Computer Science And Mathematics,
Computer Vision And Graphics
Keywords:
drug release simulation; disintegration simulation; poorly water soluble drug; mefenamic acid; Noyes-Whitney equation; cellular automata; synchrotron microtomography
Online: 22 October 2018 (11:38:04 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Drug Safety Surveillance; Adverse Drug Reaction; Ophthalmic; Ciprofloxacin; Dexamethasone
Online: 5 January 2021 (11:51:06 CET)
ARTICLE
|
doi:10.20944/preprints201809.0558.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Alginate, Chitosan, Layer-by-layer, Magnetic nanoparticles, Drug delivery, Cancer, Curcumin
Online: 28 September 2018 (09:26:48 CEST)
REVIEW
|
doi:10.20944/preprints202102.0449.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
multifunctional; hydrogel nanocomposties; tissue engineering; drug delivery; wound healing; bioprinting; biowearable devices
Online: 22 February 2021 (08:48:20 CET)
REVIEW
|
doi:10.20944/preprints202002.0099.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
retroviruses; HIV-1; reverse transcriptase; mutation rate; drug resistance, allostery
Online: 7 February 2020 (11:50:11 CET)
REVIEW
|
doi:10.20944/preprints202101.0625.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’s disease; dementia, beta-amyloid; germ theory; drug development; clinical trials; herpes; spirochetes; Chlamydia pneumoniae; Porphyromonas gingivalis; toxoplasma; mycobacteria
Online: 29 January 2021 (13:57:18 CET)
REVIEW
|
doi:10.20944/preprints201805.0378.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
annexins; inflammation; wound healing; host-pathogen interplay; drug target; translational research
Online: 27 May 2018 (11:32:34 CEST)
ARTICLE
|
doi:10.20944/preprints202006.0335.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Self-medication; dispensing; drug; prescription; misuse; Libya
Online: 28 June 2020 (10:03:59 CEST)
REVIEW
|
doi:10.20944/preprints202105.0554.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
therapeutic drug monitoring; proactive; antifungal drugs
Online: 24 May 2021 (10:24:20 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0158.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Imatinib; NLC; Tween 80; SLS; MTT Assay; Release study; Drug delivery; Breast cancer
Online: 10 May 2021 (10:13:02 CEST)
HYPOTHESIS
|
doi:10.20944/preprints201808.0127.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Big Data, Systems Models, Cancer metabolism, Cancer personalized treatment, Drug Discovery.
Online: 6 August 2018 (15:09:15 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0001.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Antitumoral drug; Choline kinase inhibition; Choline uptake
Online: 2 August 2021 (08:42:22 CEST)
REVIEW
|
doi:10.20944/preprints202104.0679.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Sildenafil; phosphodiesterase 5 inhibitors; drug repurposing; cancer; chemoadjuvant
Online: 26 April 2021 (15:02:08 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0305.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
drug repurposing; combination therapeutics; PubMed; ChEBI; disease ontology; gene ontology; drug interaction; MeSH terms; COVID-19
Online: 17 August 2022 (05:51:53 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0003.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug repositioning/repurposing; dopamine transporter (DAT); benztropine; tumoroids; signal transducer and activator of transcription (STAT); circulating tumor cells (CTC); three-dimensional (3D) culture
Online: 3 February 2020 (03:16:54 CET)
ARTICLE
|
doi:10.20944/preprints202204.0224.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
COVID-19; SARS-CoV-2; drug discovery; multitargeting; computational drug repurposing
Online: 26 April 2022 (03:39:06 CEST)
REVIEW
|
doi:10.20944/preprints201805.0319.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
annexins; inflammation; wound healing; drug target; translational research
Online: 23 May 2018 (08:19:42 CEST)
CASE REPORT
|
doi:10.20944/preprints202103.0054.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
DRESS syndrome, Eosinophilia, Adverse drug reaction, HHV-6 reactivation, Bactrim adverse reaction
Online: 2 March 2021 (09:26:48 CET)
REVIEW
|
doi:10.20944/preprints202105.0143.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Co-infection; Drug resistance; Gut microbiota; Salmonellosis; Schistosoma
Online: 7 May 2021 (12:02:03 CEST)
REVIEW
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
cannabis; cannabinergic; drug; FDA-approved; medical conditions; pharmaceutical-grade; phytocannabinoid
Online: 31 August 2020 (10:38:32 CEST)
REVIEW
|
doi:10.20944/preprints202201.0303.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Inflammation; NF-κB; drug repurposing; drug development; autoimmunity; COVID-19; multiple sclerosis; rheumatoid arthritis
Online: 20 January 2022 (11:16:25 CET)
ARTICLE
|
doi:10.20944/preprints201905.0109.v2
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
child; diarrhea; water sanitation and hygiene; rehydration solution; zinc; case management; antibacterial agents; drug utilization; community participation; India
Online: 14 May 2019 (11:46:53 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0046.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Cancer; tumor homing peptide; in silico drug discovery; complex network; chemical space network; centrality measure; similarity searching, group fusion; motif discovery; starPep toolbox software
Online: 3 February 2022 (10:14:05 CET)
ARTICLE
|
doi:10.20944/preprints202107.0270.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
drug design; falcipain; malaria; peptidomimetics; Plasmodium falciparum; virtual screening; pharmacophore.
Online: 12 July 2021 (14:48:13 CEST)
ARTICLE
|
doi:10.20944/preprints201910.0074.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Pseudomonas aeruginosa; Quorum sensing; Virtual screening; E-pharmacophore; Drug discovery.
Online: 7 October 2019 (12:33:33 CEST)
REVIEW
|
doi:10.20944/preprints202104.0574.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
smart materials; drug delivery systems; flame retardant; industrial coatings; filtration membranes; antifouling coatings.
Online: 21 April 2021 (11:47:42 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0205.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Franz-Bampa; BCS drugs; biomimetic membrane; Franz cell; passive drug transport
Online: 9 September 2020 (10:25:54 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
K-Ras; Hsp90; Cdc37; nanoclustering; cancer; drug development
Online: 31 March 2021 (15:30:27 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0221.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Cancer; cytochrome c; drug delivery; Lewis Lung Carcinoma; nanoprecipitation
Online: 14 April 2020 (14:27:15 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202004.0043.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
lactation; physiology-based lactation models; drug exposure prediction; fasting; drug safety; newborn; infant; human milk
Online: 6 April 2020 (09:11:05 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0474.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Breast cancer, genome-scale metabolic models, constraint-based analysis, divergence analysis, gene expression, metabolism, drug targets, personalized metabolic networks.
Online: 18 November 2020 (12:29:02 CET)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
galangin; Self microemulsion drug delivery system; Antioxidant damage; Pharmacokinetics
Online: 15 June 2021 (15:30:12 CEST)
REVIEW
|
doi:10.20944/preprints202109.0287.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
drug screening; monodrug or combinatorial drug screening; anti-cancer
Online: 16 September 2021 (13:46:49 CEST)
REVIEW
|
doi:10.20944/preprints202210.0347.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
monkeypox virus; infection; treatment; antiviral; drug; management; public health emergency; tecovirimat; cidofovir; bibliometric analysis
Online: 24 October 2022 (03:38:12 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0478.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
ocular drug delivery system; topical liposomes; posterior segment of the eye; safety and toler-ability; biologic activity; diabetic macular edema
Online: 25 January 2021 (10:48:51 CET)
ARTICLE
|
doi:10.20944/preprints201810.0231.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug release; electrospinning; paclitaxel; polycaprolactone; 3D matrix
Online: 11 October 2018 (06:09:26 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0770.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
BRF2; cancer; molecular dynamics simulation; drug repurposing; drug discovery
Online: 16 July 2021 (11:40:34 CEST)
COMMUNICATION
|
doi:10.20944/preprints202011.0441.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Sars-Cov-2; Proteomic,; Ghost proteome,; Alternative proteins,; AltOrf.; interactomic; drug repurposing
Online: 16 November 2020 (17:50:19 CET)
ARTICLE
|
doi:10.20944/preprints202107.0395.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Melatonin; molecular modelling; adsorption; clays; modified drug release; molecular dynamics
Online: 19 July 2021 (08:44:04 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0512.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antimicrobials; meropenem; generic drug; real-life studies; product surveillance, postmarketing; treatment outcome; pharmacovigilance
Online: 19 November 2020 (13:34:26 CET)
ARTICLE
|
doi:10.20944/preprints202301.0076.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
COVID-19; drug repurposing; long COVID; molecular docking; molecular dynamics; SARS-CoV-2
Online: 4 January 2023 (09:38:47 CET)
ARTICLE
|
doi:10.20944/preprints202103.0387.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
β-cyclodextrin; binary complex; antipsychotic drug; dissolution studies
Online: 15 March 2021 (13:44:03 CET)
ARTICLE
|
doi:10.20944/preprints202106.0717.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
hyperthyroidism; thyrotoxicosis; Graves’ disease; pregnancy; antithyroid drug; drug withdrawal; postpartum recurrence; birth defects
Online: 30 June 2021 (00:09:17 CEST)
REVIEW
|
doi:10.20944/preprints202103.0095.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
doxorubicin; drug delivery; polymers; targeted therapy; anticancer treatment; controlled release
Online: 2 March 2021 (14:14:38 CET)
REVIEW
|
doi:10.20944/preprints202203.0032.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
artificial intelligence; machine learning; drug design; covid-19; structure-based drug design; ligand-based drug design
Online: 2 March 2022 (03:00:37 CET)
ARTICLE
|
doi:10.20944/preprints202202.0194.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
antifungal resistance; isavuconazole; cystic fibrosis; pulmonary disease; Aspergillus fumigatus; pulmonary aspergillosis; respiratory disease; antifungal stewardship; therapeutic drug monitoring; minimum inhibitory concentration (MIC)
Online: 16 February 2022 (05:12:39 CET)
ARTICLE
|
doi:10.20944/preprints202008.0316.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
nanoparticles; FA-DABA-SMA; drug delivery systems; folic acid receptor alpha; intracellular disruptions; invasion and migration; breast cancer
Online: 14 August 2020 (09:49:17 CEST)
REVIEW
|
doi:10.20944/preprints202202.0067.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Antimalarial Drug; Malaria Vaccine; Drug Discovery; Artimisnine; K13; Malaria
Online: 4 February 2022 (10:22:34 CET)
ARTICLE
|
doi:10.20944/preprints202102.0505.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
adhesion; self-assembly; drug delivery; curved surface; template-assisted self-assembly; nanotechnology; single-molecule system; polymer nanocomposite.
Online: 23 February 2021 (09:35:14 CET)
REVIEW
|
doi:10.20944/preprints202207.0031.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Cell-state transitions; Phenotypic plasticity; Cancer Stem Cells; Intratumoral heterogeneity; Lamarckian Induction; Drug resistance
Online: 4 July 2022 (04:56:00 CEST)
REVIEW
|
doi:10.20944/preprints202108.0276.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
dermatophytes; antifungals; antifungal susceptibility testing; drug combination
Online: 12 August 2021 (13:16:42 CEST)
ARTICLE
|
doi:10.20944/preprints202010.0138.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Mass drug administration; Azithromycin; Gut microbiota; V4-16S rRNA sequencing
Online: 6 October 2020 (15:55:40 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0316.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Valproic acid; Drug-induced liver injury; Adverse drug reaction; Case-control study
Online: 18 January 2021 (11:11:04 CET)
REVIEW
|
doi:10.20944/preprints202109.0491.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Tuberculosis; Mycobacterium; Diagnostics; Drug Discovery; Antibiotics; Antimicrobial Re-sistance; Microfluidics; Single-Cell Analysis; Bioengineered Models
Online: 29 September 2021 (11:34:04 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0480.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
camptothecin; drug distribution; drug-membrane interaction; biophysical profiling; biomimetic models; partition coefficient; ADMET/PK prediction; small and wide-angle X-ray diffraction; fluorescence spectroscopy; human serum albumin (HSA)
Online: 20 May 2021 (10:52:33 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0675.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
pharmacogenes; transcripts; sex-bias; drug metabolism; sex differences
Online: 28 June 2021 (15:08:38 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0385.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
antibiotic resistance; antimicrobial susceptibility testing; novel diagnostics; polymicrobial; sputum; drug resistant
Online: 14 April 2021 (14:21:15 CEST)
ARTICLE
|
doi:10.20944/preprints202110.0021.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
chitosan; dexketoprofen trometamol; drug delivery; gelatin; NSAIDs; personalized medicine; smart polymers
Online: 1 October 2021 (13:53:53 CEST)
REVIEW
|
doi:10.20944/preprints202108.0447.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Interferons; IFNα; IFNß; IFNγ; antiviral; antiproliferative; immunomodulator; PEGylation; formulation; encapsulate IFNs; drug delivery system; liposomes; polymeric micelles; microparticles; nanoparticles
Online: 23 August 2021 (13:51:44 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202004.0215.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
endocanabinoid system; sleep deprivation; animal models; psychosis-like symptoms; drug development
Online: 14 April 2020 (06:28:23 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Otolaryngology
Keywords:
Drug-induced hearing loss; cochlea; outer hair cells; hearing protection; SIRT3
Online: 9 August 2021 (07:50:36 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0746.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
ABC transporter; ABCB1; P-glycoprotein; taxol; drug recognition
Online: 31 May 2021 (11:27:14 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0246.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
influenza virus; virus-host interaction; commonly prescribed drugs; drug adverse reaction
Online: 12 July 2021 (11:37:07 CEST)
REVIEW
|
doi:10.20944/preprints202305.1084.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
antibody-drug conjugate; lysosome; cathepsin; legumain; self-immolation; payload release; peptidomimetic; linker
Online: 16 May 2023 (04:51:34 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0618.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
Chemical Intolerance, Drug Intolerance, Food Intolerance, QEESI, BREESI, Multiple Chemical Sensitivity, Toxicant-induced Loss of Tolerance, Prevalence
Online: 25 June 2021 (11:49:32 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0358.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Antitumor agents; Fluorescence lifetime imaging; Medicinal chemistry; Metabolic drug; Mitochondrial carrier
Online: 15 December 2020 (08:35:30 CET)
REVIEW
|
doi:10.20944/preprints202109.0496.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
Nanomedicine; molecularly imprinted polymer; drug delivery; targeting; hybrid material
Online: 29 September 2021 (14:16:32 CEST)
REVIEW
|
doi:10.20944/preprints202106.0575.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Candida glabrata; candidiasis; virulence factors; biofilm; antifungal drug resistance
Online: 23 June 2021 (11:21:53 CEST)
REVIEW
|
doi:10.20944/preprints202112.0380.v2
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
sex differences; drug repurposing; sex-bias; sex-aware; review; therapeutics; pharmaceuticals; computational drug repurposing
Online: 8 March 2022 (10:34:42 CET)
ARTICLE
|
doi:10.20944/preprints202206.0417.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
lecithin; ginger oil; essential oil; nano-lipid; drug delivery system
Online: 30 June 2022 (08:00:31 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0621.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Auger electron; cisplatin; 191Pt; 189Pt; radio-drug; DNA double-strand break; γH2AX
Online: 25 March 2021 (14:30:14 CET)
REVIEW
Subject:
Biology And Life Sciences,
Virology
Keywords:
Chikungunya virus; alphavirus; antiviral therapy; direct-acting antivirals; host-directed antivirals; in silico screening; in vivo validation; antiviral drug development
Online: 10 June 2021 (09:15:45 CEST)
REVIEW
|
doi:10.20944/preprints201912.0386.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
resistance-associated secretory phenotype (RASP); extracellular vesicle (EV); exosome; oncosome; drug resistance; epithelial-mesenchymal transition (EMT); heat shock protein (HSP); cell stress response; hypoxia; acidosis; tumor immunology
Online: 29 December 2019 (13:46:21 CET)
REVIEW
|
doi:10.20944/preprints201810.0360.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Molecular Dynamics, CoSolvent Molecular Dynamics, Drug design, Fragment Screening, Docking
Online: 16 October 2018 (12:15:17 CEST)
COMMUNICATION
|
doi:10.20944/preprints202002.0421.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
De novo transcriptome assembly; brushtail possums; liver; brain cerebral cortex; drug and xenobiotic metabolism; chemical toxicants
Online: 28 February 2020 (11:49:29 CET)
REVIEW
|
doi:10.20944/preprints202008.0313.v2
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
drug resistance; natural diversity; C. elegans; anthelmintics
Online: 25 November 2020 (14:47:29 CET)
COMMUNICATION
|
doi:10.20944/preprints202311.1268.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
SARS-CoV-2; COVID-19; RdRp; m1A triphosphate; Antiviral Drug
Online: 21 November 2023 (07:19:23 CET)
ARTICLE
|
doi:10.20944/preprints202303.0322.v1
Subject:
Computer Science And Mathematics,
Computer Science
Keywords:
Hemolytic peptide; Network science; Half-Space Proximal Networks; Metadata Networks; Visual mining; Cluster analysis; Motif discovery; StarPep toolbox; Peptide drug discovery
Online: 17 March 2023 (10:05:05 CET)
REVIEW
|
doi:10.20944/preprints202211.0032.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’s disease; Quantum Dot Nanoparticles; PINK1; Theranostic; mitochondria; drug delivery
Online: 1 November 2022 (14:29:26 CET)
ARTICLE
|
doi:10.20944/preprints201904.0075.v1
Subject:
Chemistry And Materials Science,
Applied Chemistry
Keywords:
amphiphilc copolymer; hydrolyzable polyurea; micelle; controlled drug delivery; cancer chemotherapy
Online: 8 April 2019 (08:35:46 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0553.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Raman biosensor; Au-coated nanoparticles; hot-spot SERS substrate; anticancer drug nanocarriers; targeted drug delivery sensing; magneto-plasmonic nanoparticles.
Online: 20 April 2021 (17:43:09 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0047.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
silk fibroin; nanoparticles; drug loading content; quantification; infrared spectroscopy; FTIR spectroscopy.; nanotechnology; nanomedicine; drug delivery; controlled release
Online: 3 September 2020 (03:56:19 CEST)
REVIEW
|
doi:10.20944/preprints202201.0440.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
electrophiles; signaling; profiling; drug mechanism; drug discovery; T-REX
Online: 28 January 2022 (14:57:08 CET)
REVIEW
|
doi:10.20944/preprints202111.0250.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cell fusion; tumor hybrid cell; metastasis; drug resistance
Online: 15 November 2021 (11:07:48 CET)
ARTICLE
|
doi:10.20944/preprints202205.0256.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Extracellular matrices; Macromolecular crowding; human iPSC derived astrocytes; human iPSC derived dopaminergic neurons; drug testing
Online: 19 May 2022 (08:50:28 CEST)
REVIEW
|
doi:10.20944/preprints202203.0237.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
academy; drug development; industrial pharmacy; pharmaceutical technology; research method-ology
Online: 17 March 2022 (01:56:47 CET)