Version 1
: Received: 28 January 2022 / Approved: 4 February 2022 / Online: 4 February 2022 (10:22:34 CET)
How to cite:
Naaz, R. Progress in Antimalarial Drug Discovery and Development: Obstructions and Opportunities. Preprints2022, 2022020067. https://doi.org/10.20944/preprints202202.0067.v1
Naaz, R. Progress in Antimalarial Drug Discovery and Development: Obstructions and Opportunities. Preprints 2022, 2022020067. https://doi.org/10.20944/preprints202202.0067.v1
Naaz, R. Progress in Antimalarial Drug Discovery and Development: Obstructions and Opportunities. Preprints2022, 2022020067. https://doi.org/10.20944/preprints202202.0067.v1
APA Style
Naaz, R. (2022). Progress in Antimalarial Drug Discovery and Development: Obstructions and Opportunities. Preprints. https://doi.org/10.20944/preprints202202.0067.v1
Chicago/Turabian Style
Naaz, R. 2022 "Progress in Antimalarial Drug Discovery and Development: Obstructions and Opportunities" Preprints. https://doi.org/10.20944/preprints202202.0067.v1
Abstract
Mosquitoes conveying Plasmodium store parasites into the skin of the mammalian host. Parasites make a trip through the circulation system to the liver, where they cross a few hepatocytes prior to building up a disease. Inside the last hepatocyte the parasite goes through morphogenesis and afterward abiogenetically partitions to become more than 20,000 blood-infective parasites, called merozoites. On account of P. vivax, P. ovale, and P. cynomolgi, the parasites can stay lethargic in the liver in structures called hypnozoites. The merozoites are delivered once again into the circulation system, where they start the repetitive blood stage. Inside erythrocytes, a little division of parasites separate into male or female gametocytes. These gametocytes are ingested by the mosquito during blood taking care of, where they will duplicate explicitly, in the long run prompting the arrangement of sporozoites
Keywords
Antimalarial Drug; Malaria Vaccine; Drug Discovery; Artimisnine; K13; Malaria
Subject
Biology and Life Sciences, Anatomy and Physiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
