Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

DRESS Syndrome in a Teenage Male Associated With Hhv-6 Reactivation While on Prolonged TMP-SMX Use

Version 1 : Received: 28 February 2021 / Approved: 2 March 2021 / Online: 2 March 2021 (09:26:48 CET)

A peer-reviewed article of this Preprint also exists.

D, C.; IS, P.; AE, G. DRESS Syndrome in a Teenage Male Associated With HHV-6 Reactivation While On Prolonged TMP-SMX Use: A Case Report and Review of the Literature. SunText Review of Medical & Clinical Research 2021, 02, doi:10.51737/2766-4813.2021.029. D, C.; IS, P.; AE, G. DRESS Syndrome in a Teenage Male Associated With HHV-6 Reactivation While On Prolonged TMP-SMX Use: A Case Report and Review of the Literature. SunText Review of Medical & Clinical Research 2021, 02, doi:10.51737/2766-4813.2021.029.

Abstract

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a rare and potentially life-threatening systemic drug reaction with skin involvement. We present the unusual case of DRESS in a 16-year-old male that was treated with TMP-SMX for acne and was initially misdiagnosed with Steven Johnson Syndrome. Our case serves as an example to healthcare providers treating adverse drug reactions to having a high clinical suspicion for DRESS as delay in diagnosis and treatment can result in disseminated disease and higher patient mortality risk.

Keywords

DRESS syndrome, Eosinophilia, Adverse drug reaction, HHV-6 reactivation, Bactrim adverse reaction

Subject

Medicine and Pharmacology, Immunology and Allergy

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