Pharmaceutical Treatment of Monkeypox Virus: A Narrative Review and Bibliometric Analysis

Muhammad Aaqib Shamim; Prakisini Satapathy; Bijaya Kumar Padhi; Sai Dutt Veeramachaneni; Naushaba Akhtar; Anindita Pradhan; Abhimanyu Agrawal; Pradeep Dwivedi; Aroop Mohanty; Kreeti Bhusan Pradhan; Russell Kabir; Ali A Rabaan; Jawaher Alotaibi; Zainab A. Al Ismail; Zainab A. Alsoliabi; Ali Al Fraij; Ranjit Sah; Alfonso J. Rodriguez-Morales

doi:10.20944/preprints202210.0347.v1

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preprints.org > medicine and pharmacology > pharmacology and toxicology > doi: 10.20944/preprints202210.0347.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Pharmaceutical Treatment of Monkeypox Virus: A Narrative Review and Bibliometric Analysis

Muhammad Aaqib Shamim

Prakisini Satapathy

Bijaya Kumar Padhi

Sai Dutt Veeramachaneni

Kreeti Bhusan Pradhan

^* ,

Alfonso J. Rodriguez-Morales

Version 1 : Received: 21 October 2022 / Approved: 24 October 2022 / Online: 24 October 2022 (03:38:12 CEST)

How to cite: Shamim, M.A.; Satapathy, P.; Padhi, B.K.; Veeramachaneni, S.D.; Akhtar, N.; Pradhan, A.; Agrawal, A.; Dwivedi, P.; Mohanty, A.; Pradhan, K.B.; Kabir, R.; Rabaan, A.A.; Alotaibi, J.; Al Ismail, Z.A.; Alsoliabi, Z.A.; Fraij, A.A.; Sah, R.; Rodriguez-Morales, A.J. Pharmaceutical Treatment of Monkeypox Virus: A Narrative Review and Bibliometric Analysis. Preprints 2022, 2022100347. https://doi.org/10.20944/preprints202210.0347.v1 Shamim, M.A.; Satapathy, P.; Padhi, B.K.; Veeramachaneni, S.D.; Akhtar, N.; Pradhan, A.; Agrawal, A.; Dwivedi, P.; Mohanty, A.; Pradhan, K.B.; Kabir, R.; Rabaan, A.A.; Alotaibi, J.; Al Ismail, Z.A.; Alsoliabi, Z.A.; Fraij, A.A.; Sah, R.; Rodriguez-Morales, A.J. Pharmaceutical Treatment of Monkeypox Virus: A Narrative Review and Bibliometric Analysis. Preprints 2022, 2022100347. https://doi.org/10.20944/preprints202210.0347.v1

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MDPI and ACS Style

Shamim, M.A.; Satapathy, P.; Padhi, B.K.; Veeramachaneni, S.D.; Akhtar, N.; Pradhan, A.; Agrawal, A.; Dwivedi, P.; Mohanty, A.; Pradhan, K.B.; Kabir, R.; Rabaan, A.A.; Alotaibi, J.; Al Ismail, Z.A.; Alsoliabi, Z.A.; Fraij, A.A.; Sah, R.; Rodriguez-Morales, A.J. Pharmaceutical Treatment of Monkeypox Virus: A Narrative Review and Bibliometric Analysis. Preprints 2022, 2022100347. https://doi.org/10.20944/preprints202210.0347.v1

APA Style

Shamim, M.A., Satapathy, P., Padhi, B.K., Veeramachaneni, S.D., Akhtar, N., Pradhan, A., Agrawal, A., Dwivedi, P., Mohanty, A., Pradhan, K.B., Kabir, R., Rabaan, A.A., Alotaibi, J., Al Ismail, Z.A., Alsoliabi, Z.A., Fraij, A.A., Sah, R., & Rodriguez-Morales, A.J. (2022). Pharmaceutical Treatment of Monkeypox Virus: A Narrative Review and Bibliometric Analysis. Preprints. https://doi.org/10.20944/preprints202210.0347.v1

Chicago/Turabian Style

Shamim, M.A., Ranjit Sah and Alfonso J. Rodriguez-Morales. 2022 "Pharmaceutical Treatment of Monkeypox Virus: A Narrative Review and Bibliometric Analysis" Preprints. https://doi.org/10.20944/preprints202210.0347.v1

Abstract

Monkeypox virus infection is a recognized public health emergency. Little research has been done on treatment options for this disease. Until recently, there was not a single published work describing the usage of specific drugs in human patients with monkeypox virus infection. This paper gives the first bibliometric analysis of monkeypox treatment options based on data available on PubMed and Scopus. It also reviews the specific drugs used in the treatment of monkeypox. That includes data on Tecovirimat, Cidofovir, Brincidofovir, and Vaccinia Immune Globulin. Tecovirimat is a promising option in progressive disease in terms of efficacy and safety. However, Brincidofovir has been associated with discontinuation of treatment. Cidofovir is also not the preferred drug among physicians. Currently, Tecovirimat can be further used for the management of aggravating cases. More studies should be conducted on Tecovirimat to treat this condition, mainly through controlled trials.

Keywords

monkeypox virus; infection; treatment; antiviral; drug; management; public health emergency; tecovirimat; cidofovir; bibliometric analysis

Subject

Medicine and Pharmacology, Pharmacology and Toxicology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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