Version 1
: Received: 12 April 2020 / Approved: 14 April 2020 / Online: 14 April 2020 (06:28:23 CEST)
How to cite:
Nami, M.; Kamali, A.; Kazemiha, M.; kosagisharaf, R.; Derman, S. The Role of Endocannabinoid System in Sleep Deprivation-Induced Psychosis-Like Symptoms through Hampering Prepulse Inhibition; A Hypothesis. Preprints2020, 2020040215. https://doi.org/10.20944/preprints202004.0215.v1
Nami, M.; Kamali, A.; Kazemiha, M.; kosagisharaf, R.; Derman, S. The Role of Endocannabinoid System in Sleep Deprivation-Induced Psychosis-Like Symptoms through Hampering Prepulse Inhibition; A Hypothesis. Preprints 2020, 2020040215. https://doi.org/10.20944/preprints202004.0215.v1
Nami, M.; Kamali, A.; Kazemiha, M.; kosagisharaf, R.; Derman, S. The Role of Endocannabinoid System in Sleep Deprivation-Induced Psychosis-Like Symptoms through Hampering Prepulse Inhibition; A Hypothesis. Preprints2020, 2020040215. https://doi.org/10.20944/preprints202004.0215.v1
APA Style
Nami, M., Kamali, A., Kazemiha, M., kosagisharaf, R., & Derman, S. (2020). The Role of Endocannabinoid System in Sleep Deprivation-Induced Psychosis-Like Symptoms through Hampering Prepulse Inhibition; A Hypothesis. Preprints. https://doi.org/10.20944/preprints202004.0215.v1
Chicago/Turabian Style
Nami, M., Rao kosagisharaf and Sabri Derman. 2020 "The Role of Endocannabinoid System in Sleep Deprivation-Induced Psychosis-Like Symptoms through Hampering Prepulse Inhibition; A Hypothesis" Preprints. https://doi.org/10.20944/preprints202004.0215.v1
Abstract
The interaction between endocannabinoid (eCB) system with in key brain structures such as hippocampus, amygdala and prefrontal cortex and sleep deprivation (SD)-induced psychosis has been less studied. The present hypothesis revolves around the question whether altered chemical dynamics within the eCB system with the resultant impact on cannabinoid receptors in key cortical hubs would impact SD-induced psychosis-like symptoms. Having this investigated research is expected to pave the path towards identifying newer drug targets namely for schizophrenia.
Keywords
endocanabinoid system; sleep deprivation; animal models; psychosis-like symptoms; drug development
Subject
Medicine and Pharmacology, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
