Search | Preprints.org

Preprint SHORT NOTE | doi:10.20944/preprints202005.0287.v1

The Impacts of COVID-19 to Small Scale Fisheries in Tun Mustapha Park, Sabah, Malaysia; What Do We Know So Far?

Joannie Jomitol, Adam J. Payne, Sarmalin Sakirun, Mohd. Omar Bural

Subject: Biology And Life Sciences, Aquatic Science Keywords: COVID-19; small scale fisheries; artisarnal fishers; coastal communities; marine protected area; Malaysia; fisheries; impacts

Online: 17 May 2020 (08:46:10 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201703.0087.v1

Inhibition of Zika Virus by Marine Algae

Claudio Cirne-Santos, Caroline De Souza Barros, Caio Cesar Richter Nogueira, Renata Mendonça Campos, Valéria Teixeira, Davis Ferreira, Izabel Christina Nunes De Palmer Paixão

Subject: Biology And Life Sciences, Virology Keywords: Zika Virus, Antiviral, Marine Algae

Online: 14 March 2017 (18:34:37 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202003.0372.v1

Inhibitors of SARS-CoV-2 Main Protease from a Library of Marine Natural Products: A Virtual Screening and Molecular Modeling Study

Davide Gentile, Vincenzo Patamia, Angela Scala, Maria Teresa Sciortino, Anna Piperno, Antonio Rescifina

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: COVID-19; SARS-CoV-2; Marine natural product; Virtual screening; Docking

Online: 25 March 2020 (08:23:57 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202006.0203.v2

SH-SY5Y-derived neurons: A Human Neuronal Model System for Investigating TAU Sorting and Neuronal Subtype-Specific TAU Vulnerability

Michael Bell, Hans Zempel

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: SH-SY5Y-derived neurons; TAU sorting; neuronal identity; tauopathy; Alzheimer’s disease

Online: 23 December 2020 (10:30:47 CET)

Show abstract| Download PDF| Share

The microtubule-associated protein TAU is sorted into the axon in healthy brain neurons. Somatodendritic missorting of TAU is a pathological hallmark of many neurodegenerative diseases called tauopathies, including Alzheimer’s Disease (AD). Cause, consequence, and (patho)physiological mechanisms of TAU sorting and missorting are understudied, in part also due to the lack of readily available human neuronal model systems. The human neuroblastoma cell line SH-SY5Y is widely used for studying TAU physiology and TAU-related pathology in AD and related tauopathies. SH-SY5Y cells can be differentiated into neuron-like cells (SH-SY5Y-derived neurons) using various substances. This review evaluates whether SH-SY5Y-derived neurons are a suitable model for i) investigating intracellular TAU sorting in general, and ii) with respect to neuron subtype-specific TAU vulnerability. I) SH-SY5Y-derived neurons show pronounced axodendritic polarity, high levels of axonally localized TAU protein, expression of all six major human brain isoforms, and TAU phosphorylation similar to the human brain. As proliferative cells, SH-SY5Y cells are readily accessible for genetic engineering, stable transgene integration and leading-edge genome editing are valuable and promising tools for TAU-related studies. II) Depending on the used differentiation procedure, SH-SY5Y-derived neurons resemble cells of distinct subcortical nuclei, i.e. the Locus coeruleus (LC), Nucleus basalis (NB) and Substantia nigra (SN), all of which early affected in many tauopathies. This allows to analyse neuron-specific TAU isoform expression and intracellular localization, also in the context of vulnerability to TAU pathology. Limitations are e.g. the lack of mimicking age-related tauopathy risk factors and the difficulty to define the exact neuronal subtype of SH-SY5Y-derived neurons. In brief, this review discusses the suitability of SH-SY5Y-derived neurons for investigating TAU (mis)sorting mechanisms and neuron-specific TAU vulnerability in disease paradigms.

Preprint REVIEW | doi:10.20944/preprints201905.0066.v1

Chitin and Chitosans: Characteristics, Eco-Friendly Processes and Applications in Cosmetic Science

Cristina Casadidio, Dolores Vargas Peregrina, Maria Rosa Gigliobianco, Siyuan Deng, Roberta Censi, Piera Di Martino

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: chitin; chitosan; cosmetics; biodegradability; biomaterials; polysaccharides; green technology; marine cosmetic ingredients; marine green source; marine resources

Online: 6 May 2019 (12:37:44 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201701.0088.v2

NANOG Plays a Hierarchical Role in the Transcription Network Regulating the Pluripotency and Plasticity of Adipose Tissue-Derived Stem Cells (ASCs)

Maria Pitrone, Giuseppe Pizzolanti, Laura Tomasello, Antonina Coppola, Lorenzo Morini, Gianni Pantuso, Romina Ficarella, Valentina Guarnotta, Sebastio Perrini, Francesco Giorgino, Carla Giordano

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: Adipose derived stem cell (ASC); Regenerative medicine; embryonic stem cell marker network

Online: 20 January 2017 (04:56:06 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201702.0102.v1

Experimental Studies of Turbulence Intensity around a Tidal Turbine Support Structure

Stuart Walker, Lorenzo Cappietti

Subject: Engineering, Energy And Fuel Technology Keywords: Marine Energy; Tidal turbine; horizontal-axis marine current turbine; OCT; Turbulence; Support Structure; device wake

Online: 28 February 2017 (11:55:00 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201908.0255.v1

Macrodebris and Microplastics Pollution in Nigeria: First Report on Abundance, Distribution and Composition

Enyoh Christian Ebere, Verla Andrew Wirnkor, Verla Evelyn Ngozi, Ihenetu Stanley Chukwuemeka

Subject: Chemistry And Materials Science, Applied Chemistry Keywords: anthropogenic activities; coastal pollution; marine litter; Nigeria environment; plastics

Online: 25 August 2019 (16:42:58 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201711.0038.v1

Phospholipids of Animal and Marine Origin: Structure, Function, and Anti-Inflammatory Properties

Ronan Lordan, Alexandros Tsoupras, Ioannis Zabetakis

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: phospholipids; atherosclerosis; inflammation; anti-inflammatory; dairy; marine; meat; egg; nutrition

Online: 6 November 2017 (10:30:12 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201809.0546.v1

Motion and Dynamic Responses Approach for WindFloat Structures under Marine Loads

Ionut Cristian Scurtu, Delia Garleanu, Gabriel Garleanu

Subject: Engineering, Marine Engineering Keywords: wave energy, marine loads, RAO function, dynamic response

Online: 27 September 2018 (13:11:46 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201811.0326.v2

Cell-Based Fish: A Novel Approach to Seafood Production and an Opportunity for Cellular Agriculture

Natalie Rubio, Isha Datar, David Stachura, Kate Krueger

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: cellular agriculture; cell-based seafood; fish tissue culture; bioreactor; serum-free media; ocean conservation; marine cell culture; aquaculture

Online: 25 January 2019 (11:36:58 CET)

Show abstract| Download PDF| Share

Cellular agriculture is defined as the production of agricultural products from cell cultures rather than from whole plants or animals. With growing interest in cellular agriculture as a means to address the public health, environmental, and animal welfare challenges of animal agriculture, the concept of producing seafood from fish cell- and tissue-cultures is emerging as a means to address similar challenges with industrial aquaculture systems and marine capture. Cell-based seafood - as opposed to animal-based seafood - can combine developments in biomedical engineering with modern aquaculture techniques. Biomedical engineering developments such as closed-system bioreactor production of land animal cells create a basis for large scale production of marine animal cells. Aquaculture techniques such as genetic modification and closed system aquaculture have achieved marked gains in production that can pave the way for innovations in cell-based seafood production. Here, we present the current state of innovation relevant to the development of cell-based seafood across multiple species as well as specific opportunities and challenges that exist for advancing this science. The authors find that the physiological properties of fish cell- and tissue- culture may be uniquely suited to cultivation in vitro. These physiological properties, including hypoxia tolerance, high buffering capacity, and low-temperature growth conditions, make marine cell culture an attractive opportunity for scale production of cell-based seafood; perhaps even more so than mammalian and avian cell cultures for cell-based meats. This, coupled with the unique capabilities of crustacean tissue-friendly scaffolding such as chitosan, a common seafood waste product and mushroom derivative, presents great promise for cell-based seafood production via bioreactor cultivation. To become fully realized, cell-based seafood research will require more understanding of fish muscle culture and cultivation; more investigation into serum-free media formulations optimized for fish cell culture; and bioreactor designs tuned to the needs of fish cells for large scale production.

Preprint ARTICLE | doi:10.20944/preprints201706.0030.v1

4SM: A Novel Self-calibrated Algebraic Ratio Method for Satellite Derived Bathymetry and Water Column Correction

Yann George MOREL

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: remote sensing; attenuation coefficient; ratio method; soil line; bottom reflectance; shallow substrate; satellite derived bathymetry; water column correction; bottom typing

Online: 6 June 2017 (06:33:27 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202012.0757.v1

Remote Sensing of Ocean Fronts in Marine Ecology and Fisheries

Igor Belkin

Subject: Biology And Life Sciences, Aquatic Science Keywords: Ocean front; Marine ecology; Fisheries; Front detection; Satellite imagery; Feature-based approach

Online: 30 December 2020 (14:53:37 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201902.0023.v1

A Circular Economy Approach to Omega-3 Extraction

Rosaria Ciriminna, Antonino Scurria, Giuseppe Avellone, Mario Pagliaro

Subject: Chemistry And Materials Science, Food Chemistry Keywords: anchovy; omega-3; limonene; circular economy; fish processing waste; marine fishery discards

Online: 3 February 2019 (02:58:23 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201812.0156.v1

The Report of Marine Life Genomic Research

Guangyi Fan, Jianwei Chen, Tao Jin, Chengcheng Shi, Xiao Du, He Zhang, Yaolei Zhang, Hanbo Li, Ting Luo, Pengxu Yan, Guang Liu, Xiangqun Chi, Xiaoxuan Tan, Liangwei Li, Guilin Liu, Xiaochuan Liu, Shijie Hao, Kai Han, Xiaoyun Huang, Shuai Sun, Jing Zhou, Mengjun Yu, Lingfeng Meng, Yue Chang, Rui Zhang, Kaiqiang Liu, Mengqi Zhang, Yong Zhao, Chang Li, Jiao Guo, Xinyu Guo, Jiahao Wang, Meiqi Lv, Haoyang Gao, Yujie Liu, Yue Song, Shengjun Wang, Yang Deng, Binjie Ouyang, Jinzhong Lin, Yingjia Yu, lynn Fink, Xianwei Yang, Xun Xu, Xin Liu

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: Marine microorganisms, marine fungi, algae, marine plants, marine invertebrates, marine vertebrates, genome, metagenome

Online: 12 December 2018 (15:44:09 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202107.0273.v1

Current Research on Microbe-Plastic Interactions in the Marine Environment

Mira Latva, Vinko Zadjelovic, Robyn Wright

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Plastisphere; Plastic biofilms; Microbial communities; Marine plastic pollution; Plastic biodegradation

Online: 12 July 2021 (22:12:28 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201810.0772.v1

Beneficial Effects of Marine Algae-Derived Carbohydrates for Skin Health

Ji Hye Kim, Jae-Eun Lee, Kyoung Heon Kim, Nam Joo Kang

Subject: Medicine And Pharmacology, Dermatology Keywords: Marine algae; Carbohydrates; Oligosaccharides; Monosaccharides; Skin health; Cosmeceuticals

Online: 1 November 2018 (18:19:37 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202003.0272.v2

Toward Synthesis-derived Applications of Silver Nanoparticles

Angela SPOIALA, Denisa FICAI, Anton FICAI, Luminita CRACIUN, Aurel Mihail TITU, Ecaterina ANDRONESCU

Subject: Chemistry And Materials Science, Nanotechnology Keywords: silver nanoparticles; synthesis routes of silver nanoparticles; synthesis-derived applications; toxicity

Online: 23 March 2020 (15:24:08 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201709.0114.v1

Seawater Temperature Prediction Method for Sustainable Marine Aquaculture

Takanobu Otsuka, Yuji Kitazawa, Takayuki Ito

Subject: Computer Science And Mathematics, Information Systems Keywords: WSN; IoT; seawater temperature prediction; marine aquaculture support

Online: 23 September 2017 (11:31:13 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201812.0352.v1

Harmful Algal Blooms (HABS) along Mexican Coasts

Magnolia Gricel Salcedo-Garduño, María del Refugio Castañeda-Chávez, Fabiola Lango-Reynoso, Itzel Galaviz-Villa

Subject: Biology And Life Sciences, Other Keywords: marine biotoxins; contaminated seafood; public health

Online: 29 December 2018 (02:31:01 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202101.0545.v3

Evaluation of High-Resolution Satellite-Derived Solar Radiation Data for PV Performance Simulation in East Africa

Diane Palmer, Richard Blanchard

Subject: Engineering, Energy And Fuel Technology Keywords: Solar radiation; Satellite-derived irradiance; Global Horizontal Irradiance; Clear sky model; ground stations; validation

Online: 18 March 2021 (14:30:42 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201808.0040.v1

Modeling the Transport and Fate of Sediments Released from Marine Construction Projects in the Coastal Waters of British Columbia, Canada

David B. Fissel, Yuehua Lin

Subject: Physical Sciences, Mathematical Physics Keywords: British Columbia; environmental assessment; marine construction; circulation; numerical model; sediment model; tidal current; wind-driven current; stratification; initial dilution zone

Online: 2 August 2018 (08:36:50 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201806.0432.v1

Synthetic and Marine-Derived Porous Bone Graft Substitutes

Ana Neto, José Maria Ferreira

Subject: Chemistry And Materials Science, Biomaterials Keywords: Bone tissue engineering; biomaterials; bone scaffolds; additive manufacturing techniques/robocasting; marine-derived biomaterials

Online: 26 June 2018 (16:05:49 CEST)

Show abstract| Download PDF| Share

Preprint CONCEPT PAPER | doi:10.20944/preprints201801.0220.v1

Maristem - Stem Cells of Marine/Aquatic Invertebrates: From Basic Research to Innovative Applications

Loriano Ballarin, Baruch Rinkevich, Kerstin Bartscherer, Artur Burzynski, Sebastien Cambier, Matteo Cammarata, Isabelle Domart-Coulon, Damjana Drobne, Juanma Encinas, Uri Frank, Anne-Marie Geneviere, Bert Hobmayer, Helike Löhelaid, Daniel Lyons, Pedro Martinez, Paola Oliveri, Lorena Peric, Stefano Piraino, Andreja Ramšak, Sebastian Rakers, Fabian Rentzsch, Amalia Rosner, Tiago Henriques da Silva, Ildiko Somorjai, Sherif Suleiman, Ana Varela Coelho

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: aging; bioactive molecules; blue biotechnology; cancer; cell culture; COST Action; Europe; marine/aquatic invertebrates; regeneration; stem cells

Online: 24 January 2018 (04:14:56 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201709.0027.v1

Insights into the Diagnostic Potential of Extracellular Vesicles and their miRNA Signature from Liquid Biopsy as Early Biomarkers of Diabetic Micro/Macrovascular Complications

Valeria La Marca, Alessandra Fierabracci

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: EVs; endothelial-derived microparticles; platelet-derived microparticles; non-invasive biomarkers; miRNAs signature; diabetes associated complications; micro-macrovascular damage; diabetic nephropathy

Online: 8 September 2017 (09:38:47 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201906.0002.v1

Application of Highly Immunocompromised Mice for Establishment of Patient-Derived Xenograft (PDX) Model

Seiji Okada, Kulthida Vaeteewootthacharn, Ryusho Kariya

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: patient-derived xenograft; immunocompromised mice; precision medicine; drug screening; cancer; cell line

Online: 3 June 2019 (04:47:14 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201904.0200.v1

Fundamentals of Stem Cells: Why and How Patients' Own Adult Stem Cells Are the Next Generation of Medicine

Eckhard U. Alt, Christoph Schmitz, Xiaowen Bai

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: adipose-derived; bone regeneration; cartilage regeneration; clinical application; clinical studies; differentiation; hair loss; induced pluripotent stem cells; maxillary sinus augmentation; osteoarthritis; pluripotency; regenerative

Online: 17 April 2019 (11:25:14 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202105.0215.v1

An Annotated Checklist of the Family Cymothoidae (Isopoda: Cymothooidea) Infesting Marine Fishes from Malaysian Waters, with New Host and Geographical Records

ALIA NADHIRAH TUAH, Melissa Beata Martin, Juariah. Haji Muhamad

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Cymothoida; marine fish parasite; South China Sea; east coast Malaysia; crustacean fish parasite

Online: 10 May 2021 (15:32:00 CEST)

Show abstract| Download PDF| Share

A checklist of parasitic cymothoids from Malaysian waters is presented based on available literature and material collected from 2010 to 2020. Most of the collected specimens were recorded from waters of Terengganu, east coast of Peninsular Malaysia (facing South China Sea), whereas literature records were represented from Sarawak, along the Miri coast of northwest Borneo. The checklist comprises 18 species under 10 genera, seven of which are new records from Malaysia, which includes Anilocra nemipteri Bruce, 1987; Ceratothoa barracuda Martin, Bruce and Nowak, 2015; Ceratothoa carinata (Bianconi, 1869); Cymothoa epimerica Avdeev, 1979; Elthusa sigani Bruce, 1990; Joryma engraulidis (Barnard, 1936) and Renocila richardsonae Williams and Bunkley-Williams, 1992. Eight new host records are based on collected specimens: Anilocra nemipteri was dorsally attached on Nemipterus nemurus (Bleeker 1857), Nemipterus nematophorus (Bleeker 1854), Nemipterus tambuloides (Bleeker 1853), and Nemipterus thosaporni Russell 1991 (family Nemipteridae); Ceratothoa carinata was found in the buccal cavity of Decapterus macrosoma Bleeker 1851 (family Carangidae); Cymothoa eremita (Brunnich, 1783) was attached in the buccal cavity of Nemipterus tambuloides and Nemipterus furcosus (Valenciennes 1830); Elthusa sigani was found attached on Pterois russelli Bennett 1831 (family Scorpaenidae); and Renocila richardsonae was attached on the caudal fin of Upeneus japonicus (Houttuyn 1782) (family Mullidae). All cymothoid species listed here are known to have a Central Indo Pacific distribution, with some ranging as far as the western Indian Ocean. The cymothoid-host association is here listed from 28 fish families, with the most common reported from Carangidae (pompanos, jack mackerels, runners, scads), Engraulidae (anchovies) and Leiognathidae (ponyfishes, slipmouths). This paper is the first comprehensive treatment to update both verified literature data and deposited specimens, with a key for the family Cymothoidae in Malaysian waters.

Preprint REVIEW | doi:10.20944/preprints201811.0568.v1

From Renewable to Marine Energies Sources for Sustainable Development and Energy Transition in Morocco: Current Status and Scenario

Mostapha Tarfaoui, Mourad Nachtane, Youssef Amry, Ahmed El Moumen

Subject: Engineering, Energy And Fuel Technology Keywords: energy transition; sustainable development; efficiency energy; renewable energy; marine natural resources

Online: 26 November 2018 (03:50:26 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202101.0337.v1

Advanced Pediatric Diffuse Pontine Glioma Animal Models Pave the Way Towards Precision Medicine

Zirong Chen, Peng Peng, Xiaolin Zhang, Barbara Mania-Farnell, Guifa Xi, Feng Wan

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Diffuse intrinsic pontine glioma; molecular biology; patient derived xenografts; genetically engineered mouse model; humanized mouse model

Online: 18 January 2021 (12:50:14 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201804.0048.v1

Marine Turbine Hydrodynamics by a Boundary Element Method with Viscous Flow Correction

Francesco Salvatore, Zohreh Sarichloo, Danilo Calcagni

Subject: Engineering, Marine Engineering Keywords: marine current turbines; hydrodynamics; boundary element methods; trailing wake models; viscous flow correction

Online: 4 April 2018 (06:03:25 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201803.0224.v1

Cytokine Expression and Macrophage Localization in Xenograft and Allograft Tumor Models Stimulated with Lipopolysaccharide

Junko Masuda, Tsukasa Shigehiro, Takuma Matsumoto, Ayano Satoh, Akifumi Mizutani, Chiho Umemura, Shoki Saito, Mayumi Kijihira, Eiji Takayama, Akimasa Seno, Hiroshi Murakami, Masaharu Seno

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Myeloid-derived suppressor cells (MDSCs); dendritic cells (DCs); M1 macrophages; M2 macrophages; xenograft tumor; allograft tumor; lipopolysaccharide (LPS)

Online: 27 March 2018 (12:03:56 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201811.0351.v1

Optimization of Thermoplastic Blend Matrix HDPE/PLA with Different Nature and Level of Coupling Agent

Alessia Quitadamo, Valérie Massardier, Carlo Santulli, Marco Valente

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: blend; bio-derived polymers; compatibilization; thermoplastic matrix for composite

Online: 15 November 2018 (08:49:26 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202002.0237.v1

Development and Implementation of the Application APPMAR 1.0. A Toolbox for Management of Meteorological and Marine Data on Limited Information Regions

German Rivillas-Ospina, Marianella Bolivar, Mauro Maza Chamorro, Gabriel Ruiz, Diego Casas, Roberto Guerrero

Subject: Engineering, Marine Engineering Keywords: Colombia; Colombian Caribbean; marine climate; Mallorquín Lagoon; Puerto Colombia; Wave Watch III; wave; wind

Online: 17 February 2020 (03:32:48 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202002.0388.v1

Identification and Characterization of Biosynthetic Gene Clusters from Halophilic Marine Fungus Eurotium rubrum

Obul Reddy Bandapali, Frederik Teilfeldt Hansen, Alisha Parveen, Pradeep Phule, Emmagouni Sharath Kumar Goud, Suraj Kumar Acharya, Jens Laurids Sørensen, Abhishek Kumar

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Biosynthetic gene clusters; Eurotium rubrum; halophilic; marine genomics; nonribosomal peptide synthetase; T1pks; Terpene

Online: 26 February 2020 (10:58:18 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202311.1853.v1

Design and Optimization of Combustion Chamber for Gas Turbine Engine

Nandan Kumar Jha, Bhakti Sachin Malve, Rohit Vinod Gawde

Subject: Engineering, Aerospace Engineering Keywords: Aviation; Marine propulsion; Combustion chamber; high power to fuel ratio; Gas turbine engines

Online: 29 November 2023 (11:08:52 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201806.0093.v1

Marine Carbohydrate-Based Compounds with Medicinal Properties

Ariana Vasconcelos, Vitor Pomin

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: marine organisms; carbohydrate; glycoside; antioxidant; anticoagulant; anti-inflammatory; antitumor; antimicrobial

Online: 6 June 2018 (12:32:12 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202301.0523.v1

Potential Future Alternative Resources for Rare Earth Elements: Opportunities and Challenges

Balaram Vysetti

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: rare earth elements; deposits; alternative sources; marine sediments; river sediments; phospho-rites; red mud; fly ash; acid mine drainage; e-waste; extra-terrestrial

Online: 28 January 2023 (08:38:38 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints201906.0029.v1

The Understudied Phylum Bryozoa as a Promising Source of Anticancer Drugs

Blanca Figuerola, Conxita Avila

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: antitumour compounds; marine natural products; bioactivity; cytotoxicity; marine invertebrates

Online: 4 June 2019 (12:55:33 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202009.0198.v2

Aquatic Biota is Not Exempt from Coronavirus Infections: An Overview

Gabriel Núñez-Nogueira, Andres Arturo Granados-Berber

Subject: Biology And Life Sciences, Virology Keywords: coronavirus; aquatic organisms; fish; marine mammals; frogs; birds

Online: 22 September 2020 (11:45:01 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201805.0247.v1

Role of GDNF in Spinal Cord Injury Repair

Melissa J. Walker, Xiao-Ming Xu

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: spinal cord injury; glial cell line-derived neurotrophic factor (GDNF), GFRα-1; cRET; Schwann cells; Astrogliosis; neuroprotection; axonal regeneration; combinational therapies; neurotrauma

Online: 17 May 2018 (12:54:50 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202105.0010.v1

A Review of Optical Techniques for Coral Monitoring & Introducing Low-Cost Hyperspectral Imaging

Jonathan Teague, David A Megson-Smith, Micheal J Allen, John C.C Day, Thomas B Scott

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Coral Reef Monitoring; Reef Health; Review; Hyperspectral Imaging; Marine Optics

Online: 3 May 2021 (16:10:43 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202010.0035.v1

Photopolymerization Mechanisms at a Spatio-temporally Ultra-confined Light

Edvinas Skliutas, Miglė Lebedevaite, Elmina Kabouraki, Tommaso Baldacchini, Jolita Ostrauskaite, Maria Vamvakaki, Maria Farsari, Saulius Juodkazis, Mangirdas Malinauskas

Subject: Physical Sciences, Acoustics Keywords: Photopolymerization; Additive manufacturing; Ultrafast laser; Multiphoton lithography; Laser 3D nanolithography; Nanoscale; Organic and hybrid materials; Bio-derived materials; Functional 3D structures; Advanced material engineering

Online: 2 October 2020 (09:30:53 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202108.0004.v1

Extracellular Vesicles in Skin Wound Healing

Deimantė Narauskaitė, Gabrielė Vydmantaitė, Justina Rusteikaitė, Revathi Sampath, Akvilė Rudaitytė, Gabija Stašytė, María Isabel Aparicio Calvente, Aistė Jekabsone

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: extracellular vesicles; EVs; exosomes; mesenchymal stem cell EVs; plant-derived EVs; wound healing; scaffolds

Online: 2 August 2021 (08:57:45 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201810.0174.v1

Marine Gelatine from Rest Raw Materials

Ivan Milovanovic, Maria Hayes

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: gelatine; marine; by-products; fish; industry; extraction

Online: 9 October 2018 (05:54:23 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201806.0486.v1

Spatial Environmental Assessment Tool (SEAT): A Modeling Tool to Evaluate Potential Environmental Risks Associated with Wave Energy Converter Deployments

Craig Jones, Grace Chang, Kaustubha Raghukumar, Samuel McWilliams, Ann Dallman, Jesse Roberts

Subject: Environmental And Earth Sciences, Oceanography Keywords: marine renewable energy; ocean energy; wave energy; environmental effects; wave modeling; wave propagation; numerical modeling; sediment dynamics; risk assessment

Online: 29 June 2018 (13:09:23 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints201810.0596.v1

Biogenesis and Function of Small Non-Coding RNAs Derived from Eukaryotic Ribosomal RNA

Marine Lambert, Abderrahim Benmoussa, Patrick Provost

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: biogenesis; microRNAs; ribosomal RNA-derived fragment (rRF); ribosomes; small ribosomal RNA (srRNA); ribosomal DNA (rDNA); small RNAs

Online: 25 October 2018 (05:59:58 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201911.0239.v1

Saringosterol Acetate from a Popular Edible Seaweed, Hizikia Fusiformis Attenuated Proliferation of Human Lung Adenocarcinoma Epithelial Cells (A549 Cells) via Apoptosis Signaling Pathway

Ji-Hyeok Lee, Ju-Young Ko, Chuk Young Kim, Yong-Tae Kim, Jaeil Kim, You-Jin Jeon

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: edible marine alga; anticancer; hizikia fusiformis; saringosterol acetate; apoptosis

Online: 20 November 2019 (11:19:19 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201708.0065.v1

4SM Method Tested in the Gulf of California Suggests Field Data are Not Needed to Derive Satellite Bathymetry

Fabio Favoretto, Yann Morel, Andrew Waddington, Jorge Lopez-Calderon, Marco Cadena-Roa, Anidia Blanco-Jarvio

Subject: Biology And Life Sciences, Biophysics Keywords: 4SM; satellite derived bathymetry; water depth; water column correction; remote sensing; Landsat; San Lorenzo Channel

Online: 18 August 2017 (12:14:16 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201805.0443.v1

Smenamide A Analogues. Synthesis and Biological Activity on Multiple Myeloma Cells

Alessia Caso, Ilaria Laurenzana, Daniela Lamorte, Stefania Trino, Germana Esposito, Vincenzo Piccialli, Valeria Costantino

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: smenamides; marine natural products; peptide/polyketide molecules; synthetic analogues; functional-analogues; antiproliferative activity; MM cell line

Online: 30 May 2018 (09:00:58 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202011.0285.v1

Anti-Arthritic Effect of Chicken Embryo Tissue Hydrolyzate Against Adjuvant Arthritis in Rats (X-Ray Microtomographic and Histopathological Analysis)

Igor Rzhepakovsky, Svetlana Avanesyan, Mehmet Benlidayi, Kunaal Dhingra, Alexander Dolgalev, Natella Enukashvily, Tilman Fritsch, Stanislav Kochergin, Marina Sizonenko, Lyudmila Timchenko, Marco Vukovic, Sergey Piskov, Wolf-Dieter Grimm

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: chicken embryo tissue; hydrolyzate; food-derived bioactive peptides; adjuvant arthritis; anti-arthritic effect; in vitro and in vivo assays; X-ray microtomography

Online: 9 November 2020 (16:59:46 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202307.0739.v1

Exploring the Skin Cosmetic Benefits of Phenolic Compounds and Pigments from Marine Macroalgae: A Novel Green Approach for Sustainable Beauty Solutions

Haresh S. Kalasariya, Aryushi K. Patel, Ritul J Suthar, Leonel Pereira

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Marine macroalgae; Bioactive compounds; Phenolic compounds; Pigments; Cosmeceutical applications; Skin benefits

Online: 12 July 2023 (08:10:35 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202010.0089.v1

The Effects of the Invasive Seaweed Asparagopsis Armata on Native Rock Pool Communities: Evidences from Experimental Exclusion

Carla Silva, Marco Lemos, Rui Gaspar, Carlos Gonçalves, João Neto

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Asparagopsis armata; Biodiversity; Intertidal assemblages; Invasive exotics; Marine invasion; Non-indigenous species (NIS)

Online: 5 October 2020 (13:28:46 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints201810.0562.v1

Marine Gelatine from Rest Raw Materials

Ivan Milovanovic, Maria Hayes

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: gelatine; marine; by-products; fish; industry; extraction

Online: 24 October 2018 (09:37:38 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201810.0611.v1

AJA method and AJA Canvas as a Design Tool for Autonomous Operations

Marialena Vagia, Esten Ingar Grøtli, Aksel A. Transeth, Magnus Bjerkeng, Fredrik Haugli, Gorm Johansen

Subject: Engineering, Marine Engineering Keywords: Autonomy; LOA; design; swarms; underwater vehicles; marine; Autonomous Job Analysis; canvas

Online: 25 October 2018 (15:33:12 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201806.0064.v1

Comparative Analysis Between the In Vivo Biodistribution and Therapeutic Efficacy of Adipose-Derived Mesenchymal Stromal Cells Administered Intraperitoneally in Experimental Colitis

Mercedes Lopez-Santalla, Pablo Mancheño-Corvo, Amelia Escolano, Ramon Menta, Olga Delarosa, Juan M. Redondo, Juan A. Bueren, Wilfried Dalemans, Eleuterio Lombardo, Marina I. Garin

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: adipose-derived mesenchymal stem cells; intraperitoneal therapy; biodistribution; efficacy; colitis

Online: 5 June 2018 (11:33:18 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints201905.0063.v1

The Biotechnological Potential of Secondary Metabolites from Marine Bacteria

Boris Andryukov, Valery Mikhailov, Nataly Besednova

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: biotechnologies; marine bacteria; secondary metabolites; nonribosomal biosynthesis; antibacterial strategies

Online: 6 May 2019 (12:15:50 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202103.0771.v1

Application of Marine-Based Gold Nanomaterials in Cancer Therapy: A Mini-Review

Neda Baghban, Arezoo Khoradmehr, Iraj Nabipour, Amin Tamadon

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: cancer; gold nanoparticles; marine; drug delivery; imaging; detection

Online: 31 March 2021 (14:44:42 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201811.0117.v1

Algebras and Smarandache Types

Hee Sik Kim, J. Neggers, Sun Shin Ahn

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Smarandache algebra; point algebra; $p$-derived algebra.

Online: 5 November 2018 (12:53:07 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201808.0371.v1

Effect of Resveratrol on Reactive Oxygen Species-Induced Cognitive Impairment in Rats with Angiotensin II-Induced Early Alzheimer’s Disease

Yu-Te Lin, Yi-Chung Wu, Gwo-Ching Sun, Chiu-Yi Ho, Tzyy-Yue Wong, Ching-Huang Lin, Hsin-Hung Chen, Tung-Chen Yeh, Chia-Jung Li, Ching-Jiunn Tseng, Pei-Wen Cheng

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Alzheimer’s disease; central nervous system; hypertension; brain-derived neurotrophy factor; NADPH oxidase

Online: 21 August 2018 (06:04:03 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201907.0046.v1

Tumor Transcriptome in Patients with Lower Pectoralis Muscle Area Reveals IL-8 as a Prognostic Biomarker in Non-Small Cell Lung Cancer

Sarah Santiloni Cury, Diogo de Moraes, Paula Paccielli Freire, Grasieli de Oliveira, Douglas Venâncio Pereira Marques, Geysson Javier Fernandez, Maeli Dal-Pai-Silva, Érica Nishida Hasimoto, Patricia Pintor dos Reis, Silvia Regina Rogatto, Robson Francisco Carvalho

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: secretome; computed tomography; interleukin-8; tumor-derived factor; C2C12 cells; Cachexia

Online: 3 July 2019 (06:41:42 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201808.0102.v1

Paleoenvironment Variability during Termination I at the Reykjanes Ridge, North Atlantic

Alexander Matul, Max S. Barash, Tatyana A. Khusid, Padmasini Behera, Manish Tiwari

Subject: Environmental And Earth Sciences, Paleontology Keywords: global warming and environmental change; Late Quaternary paleoenvironments; Termination I; sea-water paleotemperature; marine microfossils; North Atlantic; stable isotopes

Online: 6 August 2018 (08:56:58 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202002.0139.v1

Restricticin B from the Marine Fungus Penicillium janthinellum and Its Inhibitory Activity on the NO Production in BV-2 Microglia Cells

Byeonung-Kyu Choi, Shin-Young Park, Song-Hee Jo, Dong-Kug Choi, Phan Thi Hoai Trinh, Hwa-Sun Lee, Van Anh Cao, Thi Duy Ngoc Ngo, Tran Thi Thanh Van, Hee Jae Shin

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: restricticin; marine fungus; Penicillium janthinellum; BV-2 microglia cells; anti-inflammatory; rotamer

Online: 11 February 2020 (09:28:35 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201808.0156.v1

Sporothrix schenckii Cell Wall Proteins-Stimulated BMDCs Are Able to Induce a Th1-Prone Cytokine Profile In Vitro

Camila Quinello, Lucas Souza Ferreira, Isabella Picolli, Maria Luiza Loesch, Deivys Leandro Portuondo, Alexander Batista-Duharte, Iracilda Zeppone Carlos

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Sporothrix schenckii; bone-marrow-derived dendritic cells; vaccine; sporotrichosis

Online: 8 August 2018 (04:32:10 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201807.0549.v1

Isolation of Smenopyrone, a Bis-g-Pyrone Polypropionate from the Caribbean Sponge Smenospongia Aurea.

Germana Esposito, Roberta Teta, Gerardo Della Sala, Joseph R. Pawlik, Alfonso Mangoni, Valeria Costantino

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: Smenospongia aurea, -pyrone, polypropionate, marine sponges, secondary metabolites, signaling molecules.

Online: 27 July 2018 (17:00:51 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202105.0398.v1

The Future of Essentially Derived Variety (EDV) Status: Predominantly More Explanations or Essential Change

John Stephen C. Smith

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: intellectual property; intellectual property protection; plant variety protection, plant breeders’ rights, essentially derived variety; utility patent; plant breeding; biotechnology.

Online: 17 May 2021 (17:03:30 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202110.0057.v1

Assessment of Microplastic Impacts in the Marine Environment: A Review

Tony Walker

Subject: Environmental And Earth Sciences, Environmental Science Keywords: impacts; microplastics; marine environment; single-use plastics; co-management initiatives

Online: 4 October 2021 (12:23:39 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201909.0221.v1

The ex-situ immobilization experiment of heavy metals in dredged marine sediments from Bohai Bay, China

Wensi Zhang, Xiao Wang, Baolin Liu

Subject: Chemistry And Materials Science, Applied Chemistry Keywords: dredged marine sediment; heavy metal; immobilization; kaolinite; limestone

Online: 19 September 2019 (11:24:05 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202109.0139.v1

Phenotype Characterization of Human Adipose-Derived Stem Cell by Flow Cytometry

Celeste Limoli, Paolo Giuseppe Limoli, Marcella Nebbioso

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Adipose-derived Stem Cell; Flow-Cytometry; Mesenchymal Stem Cell; Stromal Vascular Fraction; Immunophenotyping; Immunohistochemistry; Fluorescent Antibody Technique; Cell Separation Method

Online: 8 September 2021 (10:50:49 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201810.0324.v1

Evaluation of Efficacy and Adherence to Gluten-Free Diet in Patients with Celiac Disease

Luis Rodrigo, Isabel Perez-Martinez, Eugenia Lauret-Braña, Adolfo Suarez-Gonzalez

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: celiac disease; gluten-free diet; effectiveness; adherence; nutritionists; clinic; serology; duodenal biopsies; structured questionnaires; peptides derived from gluten in feces and urine.

Online: 15 October 2018 (16:27:32 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202005.0001.v1

Using High-Content Screening Technology as a Tool to Generate Single-Cell Patient-Derived Gene-Corrected Isogenic iPS Clones for Parkinson’s Disease Research

Peter A. Barbuti, Paul M. Antony, Bruno F.R. Santos, François Massart, Gérald Cruciani, Claire M. Dording, Jonathan Arias, Jens C. Schwamborn, Rejko Krüger

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: CRISPR-Cas9; high-content screening (HCS); fluorescent-activated cell sorting (FACS); Parkinson's disease (PD); patient-derived iPS; single-cell clones; isogenic cell lines; SNCA; alpha-synuclein; A30P

Online: 2 May 2020 (11:20:20 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint CONCEPT PAPER | doi:10.20944/preprints201911.0037.v1

ESwift: Smart and Self-Stabilizing Water-Wind Floating Turbine

Minh N. Doan, Mehdi Badri, Trung B. Tran, Yuriko Kai

Subject: Engineering, Energy And Fuel Technology Keywords: marine hydrokinetic turbine; wind energy; floating offshore wind turbine; mooring lines; floating platform; vertical axis turbine

Online: 4 November 2019 (05:13:32 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202105.0572.v1

How do Quorum Sensing Signals Mediate Algae–Bacteria Interactions?

Lachlan Dow

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: microalgae; marine bacteria; quorum sensing signals; alkyl quinolones; microbial loop

Online: 24 May 2021 (13:34:11 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201811.0346.v1

Development Model of Synergistic Sustainable Marine Ecotourism (Case Study in Pangandaran Region, West Java Province, Indonesia)

Atikah Nurhayati, Isah Aisah, Asep K Supriatna

Subject: Environmental And Earth Sciences, Environmental Science Keywords: marine ecotourism; coastal areas; fishermen; development models; sustainable

Online: 15 November 2018 (05:51:15 CET)

Show abstract| Download PDF| Share

Coastal areas in the South Coast of West Java Province have the potential to develop marine ecotourism, one of which is the Pangandaran area which must be transferred into economic value by not damaging natural resources. Marine ecotourism development is not only intended to raise foreign exchange for local governments, but are also expected to play a role in maintaining natural resources sustainably. This research aims to analyze the sustainable synergistic marine ecotourism development model. The method used in this research using quantitative descriptive method. The Quantitative descriptive method is used to describe the general condition of the research area, using primary and secondary data. The technique of taking respondents using accidental sampling as many as 50 respondents consisting of tourists, public figures, fishermen who have side jobs as a provider of marine ecotourism services. The analysis tool used is through a Rapfish model approach to measuring the synergistic model of sustainable development of marine ecotourism. Based on the results of a research on a sustainable synergistic marine ecotourism development model by measuring the ecological dimensions of environmental services in high conditions, the economic dimension of marine ecotourism is in moderate condition. Marine ecotourism technology in low conditions and social dimensions of marine ecotourism in low conditions. Model development of sustainable marine ecotourism synergistic with regard to the dimension of environmental, economic and social institutions should be able to form integrated from infrastructure to support marine ecotourism up to raise the level of income of fishermen who have a second job as a marine ecotourism providers. The infrastructure and regulatory dimensions are recommended to use the technology information to promote marine ecotourism optimally and regulations need to make marine ecotourism zoning rules and infrastructure improvements.

Preprint REVIEW | doi:10.20944/preprints202008.0087.v1

Nasal Polyposis: Insights in Epithelial-mesenchymal Transition and Differentiation of Polyp Mesenchymal Stem Cells

Emanuela Chiarella, Nicola Lombardo, Nadia Lobello, Annamaria Aloisio, Teodoro Aragona, Corrado Pelaia, Stefania Scicchitano, Heather M. Bond, Maria Mesuraca

Subject: Medicine And Pharmacology, Otolaryngology Keywords: Chronic rhinosinusitis (CR); inflammation; nasal polyps; epithelial to mesenchymal transition (EMT); Polyp derived mesenchymal stem cells (PO-MSCs)

Online: 4 August 2020 (11:07:19 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202106.0014.v1

Bioactive Compounds With Antiglioma Activity From Marine Species

Rodion Khotimchenko, Igor Bryukhovetskiy, Maksim Khotimchenko, Yuri Khotimchenko

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: antitumor activity; natural compounds; glioma multiforme; brain tumors; marine species

Online: 1 June 2021 (09:59:08 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202107.0232.v1

Seasonal Spatial and Temporal Distribution of Chlorophyll-a Concentration over Kuwait and the Arabian Gulf using Satellite and In-Situ Data

Jasem A. Albanai

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Kuwait; Arabian Gulf; Remote Sensing; ChlorophyII-a; Marine Biogeography

Online: 9 July 2021 (15:49:04 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202107.0523.v1

Recycling of Marine Carbonate Induced Calcium Isotope Heterogeneity of Arc Magmas in Subduction Zones

Xue-Gang Chen, Tao Wu, Qin Gao, Yu-Ming Lai

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Carbonate recycling; Ca isotopes; Subduction zone; Sediment melts; Arc magmas; Slab-derived fluids

Online: 22 July 2021 (16:57:46 CEST)

Show abstract| Download PDF| Share

Calcium (Ca) is an essential element constituting sedimentary carbonate in subducting sediments. Ca isotopic characteristics of subduction-related rocks could provide insight into the behavior and budget of carbonate and carbon cycles in subduction zones, due to the distinctive δ^44/40Ca ranges of sedimentary carbonate with respect to the mantle. Here, we studied the Ca isotopic compositions of arc magmas from the Northern Luzon arc (NLA), which are evolved from a depleted mantle metasomatized by slab-derived fluids and sediment melts. The δ^44/40Ca values range from 0.76 ± 0.04‰ to 1.01 ± 0.03‰ and cover the typical ranges for bulk silica earth (BSE, ~ 0.94‰) and fresh mid-ocean ridge basalt (MORB, ~ 0.83‰). The Ca isotopes of NLA volcanics are not dominantly determined by the effects of mantle partial melting or fractional crystallization, nor significantly modified by secondary alteration. Instead, the δ^44/40Ca values of NLA volcanics are controlled by the subduction-related metasomatism. The metasomatism by slab-derived fluids (mainly expelled from altered oceanic crust, AOC) dramatically elevated the contents of fluid-mobile elements (e.g., Ba and Pb) with respect to fluid-immobile elements (e.g., Ce). This process, however, rarely modified the Ca isotopes, possibly ascribed to the δ^44/40Ca similarity between AOC and the depleted mantle. The δ^44/40Ca values significantly correlated with subduction indicators (e.g., Sr-Nd isotopes, Ba/Nb, Ce/Pb, and Nb/La), demonstrating the Ca isotopes of NLA volcanics are mainly controlled by the metasomatism of sediment melts subducting from the South China Sea (SCS). Based on the thermal structures and chemical compositions of sediments subducting into global trenches, we propose that carbonate Ca isotopic signals can only be observed in the arcs with high sedimentary Ca fluxes and temperature-pressure conditions well beyond the solidus of H₂O-saturated sediment melting, e.g., NLA, Nicaragua, Guatemala, Colombia, Peru, South Chile, North Vanuatu, New Zealand, and Kermadec. The absence of such signals in other arcs suggests either limited sedimentary fluxes or much of the subducting sedimentary carbonate has been survived during plate subduction to enter the deep mantle.

Preprint ARTICLE | doi:10.20944/preprints201911.0162.v1

Characterization Of Human Pluripotent Stem Cell-Derived Hepatocytes With Adult Features And Potential For Modeling Metabolic Diseases

Gustav Holmgren, Benjamin Ulfenborg, Annika Asplund, Karin Toet, Christian X Andersson, Ann Hammarstedt, Roeland Hanemaaijer, Barbara Küppers-Munther, Jane Synnergren

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: human pluripotent stem cells; human stem cell-derived hepatocytes; in vitro; metabolic diseases; transcriptomics; maturation; characterization

Online: 14 November 2019 (11:24:24 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201807.0194.v2

Whole body vibration therapy after ischemia reduces brain damage in reproductively senescent female rats

Ami P. Raval, Marc Schatz, Pallab Bhattacharya, Nathan d’Adesky, Tatjana Rundek, W. Dalton Dietrich, Helen M. Bramlett

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: brain-derived neurotrophic factor; Frailty; Inflammasome proteins; Interleukin-1β; Peri-infarct area

Online: 23 August 2018 (07:59:58 CEST)

Show abstract| Download PDF| Share

Preprint TECHNICAL NOTE | doi:10.20944/preprints202103.0030.v1

An Efficient Low-Cost Laboratory Workflow for the Study of Blood Cells and RNA Extractions in Marine Invertebrates

Stefania Gutierrez

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Marine invertebrates; RNA extraction by LiCl precipitation; electron microscopy of blood cells; cytology stains; tunicate culture

Online: 1 March 2021 (14:19:14 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201811.0394.v3

A Sparse Autoencoder and Softmax Regression based Diagnosis Method for the Attachment on the Blades of Marine Current Turbine

Yilai Zheng, Tianzhen Wang, Bin Xin, Tao Xie, Tianzhao Tang, Yide Wang

Subject: Engineering, Electrical And Electronic Engineering Keywords: marine current turbine; blade attachment; sparse autoencoder; softmax regression

Online: 12 February 2019 (09:59:09 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202009.0263.v1

Prospects of Red King Crab Hepatopancreas Processing: Fundamental and Applied Biochemistry

Tatyana Ponomareva, Maria Timchenko, Michael Filippov, Sergey Lapaev, Evgeny Sogorin

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: marine fisheries; aquatic organisms; brachyura; anomura; commercial crab species; red king crab; Kamchatka crab; processing waste; hepatopancreas; waste recycling; enzymes; proteases; hyaluronidase

Online: 12 September 2020 (04:02:24 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202009.0532.v2

First Immunohistochemical Evidence of Human Tendon Repair Following Stem Cell Injection: A Case Report and Review of Literature

Eckhard Alt, Ralf Rothoerl, Matthias Hoppert, Hans-Georg Frank, Tobias Wuerfel, Christopher Alt, Christoph Schmitz

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: adipose derived regenerative cells; ADRCs; efficacy; point of care treatment; stem cells; stromal vascular fraction; tendon healing without scar formation; tendon regeneration

Online: 28 June 2021 (15:47:12 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202206.0333.v1

Strategies for Generating Human Pluripotent Stem Cell- Derived-Organoid Culture for Disease Modelling, Drug Screening, and Regenerative Therapy

Zakiya Gania, Syarifah Tiara Noorintan, Ni Putu Diah Pradnya Septiari, Dhea Sandra Fitriany, Fuad Gandhi Torizal

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: hPSCs derived-organoids; Culture strategy; Disease modeling; Drug screening; Regenerative therapy

Online: 24 June 2022 (08:11:15 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201810.0615.v1

Hyperspectral Image based Biodiversity of Forest Canopy and Marine Benthic Species

Vidya Manian, Alejandro Sotomayor, Ollantay Medina

Subject: Environmental And Earth Sciences, Environmental Science Keywords: hyperspectral images; multispectral images; spectral diversity; Shannon entropy; tropical forest; marine coral reefs; biodiversity; correlation.

Online: 25 October 2018 (16:30:53 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201809.0437.v2

Damage Characterisation of Nanointerleaved Woven CFRP Under Fatigue Loading

Sakineh Fotouhi, Mohamad Fotouhi, Hamed Saghafi, Giangiacomo Minak, Cristiano Fragassa

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: Fatigue; Delamination; Acoustic Emission; Failure Mechanisms; Composite Materials; Nanofibers, Marine Applications.

Online: 14 December 2018 (10:12:52 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202305.0185.v1

Analysis of Omega-3 (ω-3) Fatty Acid in Indonesia Fish Oils Using Infrared Spectroscopy and Multivariate Data Analysis

Irnawati Irnawati, Anjar Windarsih, Nurrulhidayah A. Fadzilah, Florentinus Dika Octa Riswanto, Abdul Rohman

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: EPA-DHA; marine oils; FTIR spectra; chemometrics; partial least square

Online: 4 May 2023 (04:17:19 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202005.0427.v2

Isolation of Skeletal Muscle-derived Cells Modeling Neural Crest-Derived Stem Cells for Therapeutic Use in Regenerative Periodontology

Wolf-Dieter Grimm, Nikolaj Didenko5, Kunaal Dhingra, Alexander Dolgalev, Natella Enukashvily, Tilman Fritsch, Bernd Giesenhagen5, Dmitriy Ivolgin, Marco Alexander Vukovic

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Isolation; Neural Crest-derived Stem Cells; Mechanical Dissociation; Regenerative Periodontology, Enzymatic Digestion

Online: 2 November 2020 (11:35:16 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202203.0290.v3

New Workflow Predicts Drug Targets Against SARS-CoV-2 via Metabolic Changes in Infected Cells

Nantia Leonidou, Alina Renz, Reihaneh Mostolizadeh, Andreas Dräger

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: host-virus interactions; tissue-specific model; COVID-19; SARS-CoV-2; antiviral targets; flux balance analysis; flux variability analysis; reaction knockout; host-derived enforcement; metabolic modeling; virus mutations; software engineering; Python

Online: 17 January 2023 (01:50:23 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201811.0212.v1

Osteogenesis of Multipotent Progenitor Cells using the Epigallocatechin Gallate-Modified Gelatin Sponge Scaffold in Rat Congenital Cleft-Jaw Model

Satoshi Sasayama, Tomoya Hara, Tomonari Tanaka, Yoshitomo Honda, Shunsuke Baba

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: plant polyphenol; EGCG; gelatin; bone formation; congenital bone defect; dedifferentiated fat cell; adipose-derived stem cell; scaffold

Online: 8 November 2018 (11:34:11 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202108.0536.v1

Alphavirus-driven Interferon Gamma (IFNg) Expression Inhibits Tumour Growth in Orthotopic 4T1 Breast Cancer Model

Olga Trofimova, Ksenija Korotkaja, Dace Skrastina, Juris Jansons, Karina Spunde, Maria Isaguliants, Anna Zajakina

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: interferon gamma; cancer immunotherapy; viral vectors; alphavirus; bone marrow-derived macrophages; spheroids; CD38; Pam3CSK4

Online: 30 August 2021 (10:18:08 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201910.0091.v1

Fast Detection of Two Smenamide Family-Members Using Molecular Networking

Alessia Caso, Germana Esposito, Gerardo Della Sala, Joseph R. Pawlik, Roberta Teta, Alfonso Mangoni, Valeria Costantino

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: smenospongia aurea; marine natural products; structure elucidation; anti-tumor lead molecules; smenamides; solid tumor cell lines; conformational analysis

Online: 8 October 2019 (11:08:05 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201904.0183.v1

Stochastic Modeling of Forces on Jacket-Type Offshore Structures Colonized by Marine Growth

Hamed Ameryoun, Franck Schoefs, Laurent Barille, Yoann Thomas

Subject: Engineering, Marine Engineering Keywords: marine growth; biofouling; wave loading; stochastic modeling; reliability; jacket structures

Online: 16 April 2019 (10:49:17 CEST)

Show abstract| Download PDF| Share

Working Paper ARTICLE

COI Gene and Algorithmic Analysis for Delimitation of Putative Species in Mexican Marine Nematodes

Arely Martínez-Arce, Alberto De Jesús-Navarrete, Francesca Leasi

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: marine nematodes; mtCOI; DNA taxonomy; meiofauna; Mexican Caribbean

Online: 4 July 2019 (09:51:50 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202111.0050.v1

The Neuroprotective Effects of Cannabis-Derived Phytocannabinoids and Resveratrol in Parkinson’s Disease: A Systematic Review of Pre-clinical Studies

Samay Prakash, Wayne G. Carter

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: cannabinoids; cannabis-derived phytocannabinoids; neuroprotection; resveratrol; Parkinson’s disease

Online: 2 November 2021 (12:15:49 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202009.0734.v1

AE36 HER2/neu-derived Peptide Linked to Positively Charged Liposomes with CpG-ODN as an Effective Therapeutic and Prophylactic Vaccine for Breast Cancer

Nastaran Barati, Amin Reza Nikpoor, Fatemeh Mosaffa, Atefeh Razazan, Ali Badiee, Mousa Motavallihaghi, Javad Behravan, Mahmoud Reza Jafari

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: AE36 HER2/neu-derived peptide; Nanoliposomes; CpG-ODN; Vaccine; Cancer

Online: 30 September 2020 (10:12:34 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202007.0615.v1

An Alternative Technique for Ultra-high Resolution Bathymetry and Seabed Inspection for Marine Renewables

Francisco Gemo Albino Francisco, Jan Sundberg

Subject: Engineering, Marine Engineering Keywords: Bathymetry; marine renewables; seabed inspection; high resolution survey; sonar

Online: 25 July 2020 (17:01:00 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201805.0222.v1

Sterepinic Acids A–C, New Carboxylic Acids Produced by a Marine Alga-Derived Fungus

Takeshi Yamada, Miwa Matsuda, Mayuko Seki, Megumi Hirose, Takashi Kikuchi

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: terepinic acids; Stereum sp.; marine microorganism; Undaria pinnatifida; vibralactones; phenylglycine methyl ester method

Online: 16 May 2018 (06:28:36 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202312.2257.v1

When Intruder Comes Home: GM and GE Strategies to Combat Virus Infection in Plants

Adeeb Rahman, Neeti Sanan-Mishra

Subject: Biology And Life Sciences, Plant Sciences Keywords: Pathogen Derived Resistance; RNA silencing; artificial miRNA; tasiRNA; Epigenetic editing; prime editing; Multiplexing CRISPR/Cas editing

Online: 29 December 2023 (05:55:13 CET)

Show abstract| Download PDF| Share

Search Results

344 articles found