ARTICLE
|
doi:10.20944/preprints201811.0627.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemical space; chemical data set; chemoinformatics; consensus diversity plot; drug discovery; molecular diversity; visualization
Online: 30 November 2018 (10:06:15 CET)
ARTICLE
|
doi:10.20944/preprints202008.0447.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
spike protein; SARS-CoV-2; mutation; drug repurposing; digitoxin
Online: 20 August 2020 (08:24:41 CEST)
REVIEW
|
doi:10.20944/preprints201810.0512.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
nanotechnology; diatom; biosilica; drug delivery; hybrid devices
Online: 22 October 2018 (16:15:47 CEST)
ARTICLE
|
doi:10.20944/preprints201709.0061.v2
Subject:
Chemistry And Materials Science,
Surfaces, Coatings And Films
Keywords:
expired drug; corrosion inhibitor; potentiodynamic polarization; electrochemical impedance spectroscopy; AFM
Online: 17 October 2017 (04:18:30 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0279.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Blood-Brain Barrier, Penetrating Peptides, Machine learning techniques, Drug delivery, Therapeutic peptides
Online: 10 June 2021 (08:13:15 CEST)
REVIEW
|
doi:10.20944/preprints202009.0417.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
schizophrenia; stress; drug policy; environment; contaminants; pesticides; fungi; prohibition
Online: 18 September 2020 (04:21:43 CEST)
ARTICLE
|
doi:10.20944/preprints201901.0046.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Keywords: methotrexate, cubic phase, magnetocubosomes, monoolein, liquid crystalline phase, drug delivery system, alternating magnetic field
Online: 4 January 2019 (14:32:38 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
acute coronary syndromes; myocardial infarction; STEMI; Covid-19, infectious disease; respiratory infections; pathophysiology; percutaneous coronary intervention; thrombolysis; drug treatment
Online: 7 May 2020 (12:49:39 CEST)
ARTICLE
|
doi:10.20944/preprints202102.0436.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
silver nanoparticles; biofilm; orthodontic wire; drug resistance; oral-Streptococcus
Online: 19 February 2021 (12:23:26 CET)
ARTICLE
|
doi:10.20944/preprints201910.0027.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
PLGA; drug delivery systems; microfluidics; nanoparticles; microparticles
Online: 2 October 2019 (09:21:39 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0310.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
primary open angle glaucoma; dorzolamide/timolol fixed combination; drug efficacy; safety
Online: 24 April 2018 (08:36:58 CEST)
REVIEW
|
doi:10.20944/preprints202208.0021.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Solubility; Bioavailability; Dissolution; Poorly Soluble Drugs; Drug Solubility Enhancement Techniques
Online: 1 August 2022 (10:44:13 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0245.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
Chitosan-g-PMMA amphiphilic nanoparticles; thiolated polymers; mucoadhesion; mucosal drug delivery; Caco2 and HT29-MTX cell lines; apparent permeability in vitro.
Online: 18 April 2018 (16:28:21 CEST)
ARTICLE
|
doi:10.20944/preprints201805.0076.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Oral cancer; mTOR pathway; secreted glycoprotein; drug resistance
Online: 3 May 2018 (12:47:14 CEST)
REVIEW
|
doi:10.20944/preprints201906.0145.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
multiple myeloma; angiogenesis; extramedullary disease; drug resistance; bone marrow microenvironment.
Online: 16 June 2019 (10:05:40 CEST)
REVIEW
|
doi:10.20944/preprints202103.0771.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
cancer; gold nanoparticles; marine; drug delivery; imaging; detection
Online: 31 March 2021 (14:44:42 CEST)
ARTICLE
|
doi:10.20944/preprints201711.0090.v1
Subject:
Medicine And Pharmacology,
Dentistry And Oral Surgery
Keywords:
drug delivery; dentine; diffusion; bio-active molecules; CFD; μ-LIF; microfluidics
Online: 14 November 2017 (10:15:29 CET)
ARTICLE
|
doi:10.20944/preprints202002.0154.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
pediatric drug poisoning; emergency department; corrosive; mortality
Online: 11 February 2020 (15:57:47 CET)
ARTICLE
|
doi:10.20944/preprints201905.0370.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Targeted drug delivery, VX2 tumor, breast cancer, cryoablation, cryo-assisted injection, cryo-assisted resection, blue dye, epirubicin.
Online: 30 May 2019 (13:44:41 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0229.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
extracellular vesicles; melanoma; doxorubicin; drug delivery systems.
Online: 11 May 2021 (10:19:50 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0307.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
TiO2 nanoparticles; antibacterial activity; multi-drug-resistance pathogens; MRSA; E. coli. P. aeruginosa; genotoxicity
Online: 10 November 2020 (12:09:17 CET)
REVIEW
|
doi:10.20944/preprints201807.0226.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
galvanic replacement; photothermal therapy; drug delivery; nanoparticles; cancer treatment
Online: 13 July 2018 (05:11:21 CEST)
REVIEW
|
doi:10.20944/preprints202105.0311.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Angiotensin converting enzyme 2; breast feeding; drug therapy; pregnancy; severe acute respiratory syndrome coronavirus 2
Online: 13 May 2021 (15:26:34 CEST)
ARTICLE
|
doi:10.20944/preprints201907.0043.v1
Subject:
Computer Science And Mathematics,
Applied Mathematics
Keywords:
Network biology; LINE; lncRNA; protein; miRNA; Drug; disease
Online: 2 July 2019 (11:42:26 CEST)
ARTICLE
|
doi:10.20944/preprints201803.0144.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
sea anemone; drug discovery; cancer; antiangiogenic; endothelial cells; RGD motif; Kunitz type inhibitor
Online: 19 March 2018 (08:15:38 CET)
ARTICLE
|
doi:10.20944/preprints202108.0498.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
CML; Disease progression; common biomarker; drug target; ANRD36.
Online: 3 January 2024 (12:14:25 CET)
ARTICLE
|
doi:10.20944/preprints201905.0297.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
lignin; drug release; paracetamol; disintegration
Online: 24 May 2019 (12:40:01 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0308.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Indonesia; biodiversity; novel antibiotics; drug screening; bioactivity; gene cluster networking; GNPS
Online: 13 May 2021 (14:05:00 CEST)
ARTICLE
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
kinase inhibitors; pure drug nanoparticles; drug nanocrystals; bottom-up nanonization; nanoprecipitation; microfluidics; flow focusing technologies
Online: 2 March 2021 (11:29:18 CET)
REVIEW
|
doi:10.20944/preprints202109.0432.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Non-genetic heterogeneity; multistability; drug-tolerant persisters; phenotypic plasticity; biological noise; epithelial-mesenchymal plasticity; PAGE4
Online: 24 September 2021 (12:44:34 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0250.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
AI drug discovery; mTOR; rapalog; C. elegans; cancer; longevity
Online: 15 February 2023 (02:42:57 CET)
CONCEPT PAPER
|
doi:10.20944/preprints202001.0040.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
cybernetics; complex systems; new drug development; human system
Online: 5 January 2020 (15:38:27 CET)
ARTICLE
|
doi:10.20944/preprints202008.0283.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Adverse drug reaction; COVID-19 treatment
Online: 12 August 2020 (11:12:41 CEST)
REVIEW
|
doi:10.20944/preprints202104.0733.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Topoisomerase I; irinotecan; camptothecin; ubiquitination; proteasomal degradation; drug resistance
Online: 28 April 2021 (08:44:34 CEST)
REVIEW
|
doi:10.20944/preprints201806.0384.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Trypanosoma brucei; surface proteome; endomembrane system; endocytosis; drug development
Online: 25 June 2018 (11:33:03 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0169.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Split-intein circular ligation of peptides and proteins (SICLOPPS); cyclic peptide libraries; protein–protein interactions; drug; gateway cloning
Online: 6 April 2021 (10:19:49 CEST)
ARTICLE
|
doi:10.20944/preprints201811.0561.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
cheminformatics, drugs, drug-likeness, drug discovery, natural products
Online: 23 November 2018 (13:56:32 CET)
ARTICLE
|
doi:10.20944/preprints202010.0196.v2
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
drug discovery; artificial intelligence; protein discovery; binding prediction; synthetic molecule generation; synthetic drug
Online: 20 November 2020 (11:30:03 CET)
REVIEW
|
doi:10.20944/preprints201906.0002.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
patient-derived xenograft; immunocompromised mice; precision medicine; drug screening; cancer; cell line
Online: 3 June 2019 (04:47:14 CEST)
REVIEW
|
doi:10.20944/preprints201810.0204.v2
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
DNA origami; aptamer; DNA nanotechnology; protein nano array; biosensor; logic gate; enzyme cascade; drug delivery system; targeted therapy; molecular robotics
Online: 22 October 2018 (10:57:21 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Parkinson’s disease; precision medicine; personalized medicine; GBA; Glucocerebrosidase; GCase; LRRK2; Leucine-rich repeat kinase-2; Dopamine; PD drug trials; PD risk variants
Online: 14 September 2020 (00:22:59 CEST)
ARTICLE
|
doi:10.20944/preprints202210.0223.v3
Subject:
Biology And Life Sciences,
Virology
Keywords:
Drug discovery; Systems biology; SARS-CoV-2; Dengue; Influenza A; RSV; cell viability analysis; antivirals; in vitro validation; in vivo validation
Online: 22 March 2024 (16:46:59 CET)
ARTICLE
|
doi:10.20944/preprints202104.0222.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
ocular surface disease; dry eye disease; antioxidant; Xanthohumol; drug delivery; drug formulation; PLGA; nanoparticles
Online: 8 April 2021 (09:09:24 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0311.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Chitosan; Silver nanoparticles; Graphene oxide; Nanocomposites; Antibacterial property; Drug delivery
Online: 12 April 2021 (13:59:44 CEST)
REVIEW
|
doi:10.20944/preprints202108.0112.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Epitranscriptomics, Immune checkpoint blockage (ICB) therapy, anti-PD-1/PD-L1 drug resistance, Personalized medicine, CISH, microRNAs
Online: 4 August 2021 (13:02:22 CEST)
REVIEW
|
doi:10.20944/preprints201810.0507.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
liposomes, exosomes, extracellular vesicles, drug delivery, drug targeting, bioinspired systems, engineered systems.
Online: 22 October 2018 (15:35:20 CEST)
REVIEW
|
doi:10.20944/preprints202203.0071.v2
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
rheumatoid arthritis; precision medicine; new treatment; drug development; method development
Online: 25 May 2022 (04:59:01 CEST)
ARTICLE
|
doi:10.20944/preprints201911.0024.v1
Subject:
Computer Science And Mathematics,
Information Systems
Keywords:
Iranian traditional medicine; Persian medicine; ontology; knowledge-base; Mizaj; temperament; new drug discovery
Online: 3 November 2019 (17:07:50 CET)
ARTICLE
|
doi:10.20944/preprints202109.0020.v2
Subject:
Social Sciences,
Behavior Sciences
Keywords:
Alcohol drinking; Drug misuse; Family environment; Indonesian students.
Online: 3 September 2021 (14:46:44 CEST)
REVIEW
|
doi:10.20944/preprints202004.0012.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemoinformatics; chemical space; database; LANaPD; molecular diversity; drug discovery; natural sources
Online: 2 April 2020 (04:47:13 CEST)
REVIEW
|
doi:10.20944/preprints202107.0650.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
chronic disorders; inflammation; human superorganism; holobiont; microbiome; multimorbidity; microimmunosome; polypharmacy; drug safety; sustainable healthcare
Online: 29 July 2021 (11:37:20 CEST)
REVIEW
|
doi:10.20944/preprints202102.0405.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
drug repurposing; antifungal therapy; antifungal mechanism; clinical application; antifungal agents
Online: 18 February 2021 (10:21:38 CET)
REVIEW
|
doi:10.20944/preprints202105.0726.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Artificial Intelligence; Drug Delivery; Cancer; Nanomedicines; Therapeutic
Online: 31 May 2021 (09:59:30 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0052.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNAi; drug delivery; siRNA delivery; DsiRNA delivery; RNAi delivery; Chol-DsiRNA polymer micelles; Chol-siRNA polymer micelles
Online: 3 September 2021 (08:56:48 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0448.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
acetyleugenol; Acacia nilotica; anti-tuberculosis; Serine/Threonine kinases; multi-drug resistant TB
Online: 24 April 2020 (14:12:33 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0349.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Hypoxia-inducible factor; cancer; hypoxia; drug discovery; medicinal chemistry; virtual screening; molecular dynamics simulation; MM-PBSA; Drug discovery
Online: 28 February 2022 (08:40:24 CET)
REVIEW
|
doi:10.20944/preprints201808.0306.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Candida glabrata, drug resistance, tolerance, FKS, MSH2, echinocandin, azole
Online: 17 August 2018 (12:43:43 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
pharmacology; drug development; sodium channel; potassium channel; TRP channel; HCN channels
Online: 8 August 2019 (12:31:26 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0369.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; SARS-CoV-2; spike protein; ACE1; ACE2; host-virus interaction; drug repurposing
Online: 2 August 2020 (09:23:18 CEST)
ARTICLE
|
doi:10.20944/preprints202201.0082.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; cancer stem cell; therapy resistance; cationic amphiphilic drug; lysosome-dependent cell death
Online: 6 January 2022 (11:51:28 CET)
REVIEW
|
doi:10.20944/preprints202012.0029.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
drug delivery; immune response; inflammation; critical solution temperature; scaffolds; smart polymers; tissue engineering; thermo-responsive; wound healing.
Online: 1 December 2020 (13:55:35 CET)
ARTICLE
|
doi:10.20944/preprints201903.0055.v1
Subject:
Social Sciences,
Psychology
Keywords:
drug, impulsivity, sensation-seeking, peer conflict, adolescent.
Online: 5 March 2019 (11:29:30 CET)
REVIEW
|
doi:10.20944/preprints201909.0327.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
glioblastoma; renin-angiotensin system; cancer stem cells; drug repurposing
Online: 29 September 2019 (06:21:26 CEST)
REVIEW
|
doi:10.20944/preprints202012.0044.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Integrins; Tumor Microenvironment; Drug Resistance; Migration; Metastasis; Solid Tumors; The Cancer Genome Atlas; Gene Expression; Computational Biology; Therapeutic Targeting
Online: 1 December 2020 (18:26:11 CET)
REVIEW
|
doi:10.20944/preprints202105.0643.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Nanocarriers; Nanotheranostics; Nuclear Medicine; Nanoparticles; Drug delivery
Online: 26 May 2021 (14:00:58 CEST)
ARTICLE
|
doi:10.20944/preprints201812.0018.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
colorectal cancer; differentially expressed genes; biomarkers; protein-protein interaction; reporter biomolecules; candidate drugs; systems biology; drug repositioning
Online: 29 December 2018 (07:05:05 CET)
ARTICLE
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Sepiapterin; triacetyl-β-cyclodextrin (TAβCD); hydrophilic drug/cyclodextrin complexes; spray-drying; methoxy-poly(ethylene-glycol)-poly(epsilon-caprolactone) (mPEG-PCL) nanoparticles
Online: 24 May 2019 (11:42:42 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0031.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antibiotics; antimicrobial resistance; antimicrobial stewardship; AWaRe; Pharmacovigilance; Lareb; adverse drug reactions
Online: 2 August 2021 (12:27:02 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0374.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
STAT3 as a drug target; cyclic STAT3 decoy; oligodeoxynucleotide inhibitor; head and neck cancer
Online: 29 April 2018 (10:10:00 CEST)
ARTICLE
|
doi:10.20944/preprints201808.0319.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
adverse drug reactions; spontaneous reporting; causality; ADR; severity
Online: 18 August 2018 (05:17:05 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0752.v1
Subject:
Medicine And Pharmacology,
Dentistry And Oral Surgery
Keywords:
rational drug use; dentist; prescribe
Online: 31 October 2018 (11:13:37 CET)
ARTICLE
|
doi:10.20944/preprints202104.0047.v2
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Hydrogels; Sodium alginate; Betamethasone; Drug delivery; Cartilage tissue engineering
Online: 6 April 2021 (10:03:04 CEST)
REVIEW
|
doi:10.20944/preprints202105.0337.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antibacterial agents; antibiotics; COVID-19; drug misuse; odontogenic infection
Online: 14 May 2021 (14:03:42 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0088.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
There are many molecules used as drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in addition to that it has the ability to induce apoptosis in cancer cells. However, the effect of TUD-1 appears to act as cell death inducer, regardless of whether it is necrosis or apoptosis. Unfortunately, recent studies indicate that a proportion of cells undergo necrosis rather than apoptosis, which limits the use of TUD-1 as a secure treatment. On the other hand, lithium considered as necrosis inhibitor element. Hence, current study based on the idea of production a new Li/TUD-1 by incorporated mesoporous silica (TUD-1 type) with lithium in order to produce a new compound that has the ability to activate apoptosis by mesoporous silica (TUD-1 type) and at the same time can inhibit the activity of necrosis by lithium. Herein, lithium was incorporated in TUD-1 mesoporous silica by
Online: 4 October 2018 (15:54:02 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0359.v2
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
1, 2, 4-Triazine; Lanosterol 14a-demethylase (CYP51); Drug Resistance; Molecular Docking; Molecular Dynamic Simulation.
Online: 17 August 2021 (12:27:02 CEST)
ARTICLE
|
doi:10.20944/preprints201806.0192.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
β4-galactosyltransferase 4; transcriptional mechanism; sensor cells; colon cancer; drug screening
Online: 12 June 2018 (12:51:07 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0157.v1
Subject:
Business, Economics And Management,
Accounting And Taxation
Keywords:
National Centralized Drug Procurement; "4+7" policy; drug price; interrupted time series; volume-based procurement.
Online: 6 April 2021 (08:18:10 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0054.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
3D printing; semi-solid extrusion 3D printing; additive manufacturing; extemporaneous manufacturing; drug delivery; personalized dosage forms; veterinary medicine; prednisolone
Online: 2 November 2020 (14:59:30 CET)
ARTICLE
|
doi:10.20944/preprints202012.0281.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
covid-19; drug repurposing; topological data analysis; persistent homology
Online: 11 December 2020 (12:57:28 CET)
REVIEW
|
doi:10.20944/preprints201802.0190.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Alzheimer’s disease; biomimetic nanocarriers; blood-brain barrier; dementia; drug targeting; lipid cubic phases; nanoemulsion; SR-BI; scavenger receptors
Online: 28 February 2018 (07:49:13 CET)
REVIEW
|
doi:10.20944/preprints202107.0506.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Drug repositioning; Molecular modelling; Beauvericin
Online: 22 July 2021 (07:48:33 CEST)
REVIEW
|
doi:10.20944/preprints202101.0325.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
pediatric cancer; nanoparticles; drug delivery system; liposome; leukemia; lymphoma; osteosarcoma; Ewing sarcoma; glioma; blood-brain barrier
Online: 18 January 2021 (11:58:32 CET)
REVIEW
|
doi:10.20944/preprints201912.0179.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
globular set; category theory; multidimensional; visual recognition; drug-resistant epilepsy; transcranial magnetic stimulation.
Online: 13 December 2019 (10:37:03 CET)
REVIEW
|
doi:10.20944/preprints202105.0036.v2
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Electrophile; Drug Design; Covalent Drug; Chemical Biology
Online: 19 October 2021 (10:28:15 CEST)
ARTICLE
|
doi:10.20944/preprints201909.0063.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
FABP4; A-FABP; aP2; antidiabetes; antiobesity; antiatherosclerosis; anticancer; computational tools; computer-aided drug discovery
Online: 5 September 2019 (15:39:58 CEST)
REVIEW
|
doi:10.20944/preprints202106.0305.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
dietary flavonoids; cardioprotective effects; ROS scavenging; myocardial dysfunction; bioavailability and drug metabolism; toxicity; drug discovery
Online: 11 June 2021 (08:44:01 CEST)
ARTICLE
|
doi:10.20944/preprints201811.0574.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
activity cliff; activity landscape plotter; epigenetics; docking; drug discovery; D-tools; molecular dynamics; Epi-polypharmacology; SmART; structure-activity relationships
Online: 26 November 2018 (07:14:05 CET)
ARTICLE
|
doi:10.20944/preprints202001.0219.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
protruding features; spherical virus; point arrays; surface modifications; VLP; drug delivery; icosahedral; nanomedicine; ligand binding
Online: 20 January 2020 (06:59:09 CET)
REVIEW
|
doi:10.20944/preprints202201.0146.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Nanomedicine; drug resistance; lung cancer; chemotherapeutic agents; drug delivery
Online: 11 January 2022 (13:48:22 CET)
ARTICLE
|
doi:10.20944/preprints201908.0177.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
chronic myeloid leukemia; tyrosine kinase inhibitor; adverse drug event; quality of life; second-generation tyrosine kinase inhibitor; nilotinib
Online: 16 August 2019 (08:09:07 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0161.v2
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
COVID-19; docking; drug repurposing; natural products; in silico drug design; viral replication inhibition
Online: 1 June 2020 (02:42:54 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0212.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Geophila obvallata; toxicity; Sub-acute; Drug therapy
Online: 13 April 2020 (11:38:46 CEST)
REVIEW
|
doi:10.20944/preprints201807.0143.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Aromatic hydroxy metabolites; arenolic drug metabolites; metabolic O-dealkylation; metabolic aromatic ring hydroxylation; primary and auxiliary pharmacophores; auxophores; metabolic modification of drug activity
Online: 9 July 2018 (13:28:16 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
adlay; adlay bran oil; cytochrome P450; food-drug interactions; rats
Online: 10 September 2019 (03:16:30 CEST)
REVIEW
|
doi:10.20944/preprints201807.0518.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
virus; antiviral agent; drug target; drug side effect; innate immunity; precision medicine; systems biology
Online: 26 July 2018 (15:33:03 CEST)
ARTICLE
|
doi:10.20944/preprints201811.0608.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
spheroids; concentration gradient generator; drug screening; high-throughput
Online: 28 November 2018 (10:08:05 CET)
ARTICLE
|
doi:10.20944/preprints201809.0587.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
machine learning; conotoxins; cone snails; venom; drug discovery
Online: 29 September 2018 (07:39:42 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0236.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
essential oils; drug resistant microorganisms; antimicrobial activity; antifungal activity; medicinal plants
Online: 11 October 2018 (11:51:16 CEST)
ARTICLE
|
doi:10.20944/preprints201907.0220.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
diversity; fragment-based drug discovery; library design; library size
Online: 19 July 2019 (07:54:41 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0178.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
DILIrank; DILI; drug hepatotoxicity; QSAR; nested cross-validation; virtual screening; in silico
Online: 14 February 2020 (02:24:04 CET)