Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Chitosan/Silver Nanoparticle/Graphene Oxide Nanocomposites with Multi-drug Release, Antimicrobial, and Photothermal Conversion Functions

Version 1 : Received: 7 April 2021 / Approved: 12 April 2021 / Online: 12 April 2021 (13:59:44 CEST)

A peer-reviewed article of this Preprint also exists.

Su, Z.; Sun, D.; Zhang, L.; He, M.; Jiang, Y.; Millar, B.; Douglas, P.; Mariotti, D.; Maguire, P.; Sun, D. Chitosan/Silver Nanoparticle/Graphene Oxide Nanocomposites with Multi-Drug Release, Antimicrobial, and Photothermal Conversion Functions. Materials 2021, 14, 2351. Su, Z.; Sun, D.; Zhang, L.; He, M.; Jiang, Y.; Millar, B.; Douglas, P.; Mariotti, D.; Maguire, P.; Sun, D. Chitosan/Silver Nanoparticle/Graphene Oxide Nanocomposites with Multi-Drug Release, Antimicrobial, and Photothermal Conversion Functions. Materials 2021, 14, 2351.

Journal reference: Materials 2021, 14, 2351
DOI: 10.3390/ma14092351

Abstract

In this work, we designed and fabricated a multifunctional nanocomposite system which consists of chitosan, raspberry-like silver nanoparticles and graphene oxide. Room temperature atmospheric pressure microplasma (RT-APM) process provides a rapid, facile, and environment-friendly method for introducing silver nanoparticles into the composite system. By loading different drugs onto the polymer matrix and/or graphene oxide, our composite can achieve a pH controlled dual drug release with release profile specific to the drugs used. In addition to its strong antibacterial ability against E. coli and S. aureus, our composite also demonstrates excellent photothermal conversion effect under irradiation of near infrared lasers. These unique functionalities point to it’s the potential of nanocomposite system in multiple applications areas such as multimodal therapeutics in healthcare, water treatment, and anti-microbial, etc.

Subject Areas

Chitosan; Silver nanoparticles; Graphene oxide; Nanocomposites; Antibacterial property; Drug delivery

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.