Version 1
: Received: 17 February 2021 / Approved: 19 February 2021 / Online: 19 February 2021 (12:23:26 CET)
How to cite:
Farheen, S.; Oanz, A.M.; Khan, N.; Umar, M.S.; Jamal, F.; Kashif, M.; Alshameri, A.W.; Khan, S.; Owais, M. Antimicrobial Effect of Nano-Silver Against Oral Streptococci: Implications in Containment of Bacterial Biofilm on Orthodontal Appliances. Preprints2021, 2021020436. https://doi.org/10.20944/preprints202102.0436.v1
Farheen, S.; Oanz, A.M.; Khan, N.; Umar, M.S.; Jamal, F.; Kashif, M.; Alshameri, A.W.; Khan, S.; Owais, M. Antimicrobial Effect of Nano-Silver Against Oral Streptococci: Implications in Containment of Bacterial Biofilm on Orthodontal Appliances. Preprints 2021, 2021020436. https://doi.org/10.20944/preprints202102.0436.v1
Farheen, S.; Oanz, A.M.; Khan, N.; Umar, M.S.; Jamal, F.; Kashif, M.; Alshameri, A.W.; Khan, S.; Owais, M. Antimicrobial Effect of Nano-Silver Against Oral Streptococci: Implications in Containment of Bacterial Biofilm on Orthodontal Appliances. Preprints2021, 2021020436. https://doi.org/10.20944/preprints202102.0436.v1
APA Style
Farheen, S., Oanz, A.M., Khan, N., Umar, M.S., Jamal, F., Kashif, M., Alshameri, A.W., Khan, S., & Owais, M. (2021). Antimicrobial Effect of Nano-Silver Against Oral Streptococci: Implications in Containment of Bacterial Biofilm on Orthodontal Appliances. Preprints. https://doi.org/10.20944/preprints202102.0436.v1
Chicago/Turabian Style
Farheen, S., Saba Khan and Mohammad Owais. 2021 "Antimicrobial Effect of Nano-Silver Against Oral Streptococci: Implications in Containment of Bacterial Biofilm on Orthodontal Appliances" Preprints. https://doi.org/10.20944/preprints202102.0436.v1
Abstract
Among various metal-based nanoparticles, silver nanoparticles (AgNPs) manifest superior inhibitory effect against several microorganisms. In fact, the AgNPs based therapy has been reported to inhibit both sensitive as well resistant isolates of bacteria and other disease causing microbes with equal propensity. Keeping this fact into consideration, we executed bio-mediated synthesis of AgNPs employing Hibiscus rosa sinensis flower extract. The as-synthesized AgNPs were evaluated for their potential to inhibit Streptococcus mutans (S. mutans), one of the main causative bacteria for dental caries. Beside several other reasons, orthodontic appliances have also been reported to facilitate infliction of oral cavity with a range of microbes including S. mutans. To determine the growth inhibitory and anti-adherence activity of AgNPs on orthodontic appliance, we performed microbiological assays employing AgNPs adsorbed on to the orthodontic wires. Topographic analysis of orthodontic wires was executed by scanning electron microscopy. In addition to antimicrobial and antibiofilm activity against oral S. mutans, the as-fabricated AgNPs demonstrated significant inhibitory and anti-biofilm properties against other biofilm forming bacteria such as Escherichia coli and Listeria monocytogenes as well.
Keywords
silver nanoparticles; biofilm; orthodontic wire; drug resistance; oral-Streptococcus
Subject
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
