Working Paper Review Version 1 This version is not peer-reviewed

Non-Canonical Ion Channel Behaviour in Pain

Version 1 : Received: 7 August 2019 / Approved: 8 August 2019 / Online: 8 August 2019 (12:31:26 CEST)

How to cite: Ciotu, C.I.; Tsantoulas, C.; Meents, J.; Lampert, A.; McMahon, S.; Ludwig, A.; Fischer, M.J. Non-Canonical Ion Channel Behaviour in Pain. Preprints 2019, 2019080110 Ciotu, C.I.; Tsantoulas, C.; Meents, J.; Lampert, A.; McMahon, S.; Ludwig, A.; Fischer, M.J. Non-Canonical Ion Channel Behaviour in Pain. Preprints 2019, 2019080110

Abstract

Ion channels contribute fundamental properties to all cell membranes. The ion channels are highly diverse in conductivity, structure, location and function. However, many of them can be regulated by common mechanisms, such as voltage or (de-)phosphorylation. Considering primarily pain-related ion channels, this review covers more novel and less known features of ion channel function, also with the aim to transfer knowledge between fields, which get inevitably more separate due to their size.

Subject Areas

pharmacology; drug development; sodium channel; potassium channel; TRP channel; HCN channels

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