ARTICLE
|
doi:10.20944/preprints202311.1488.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
tuberculosis; statins; host-directed therapy; foam cells; granulomas; NLRP3 inflammasome; mevalonate-kinase deficiencies
Online: 23 November 2023 (08:23:48 CET)
REVIEW
|
doi:10.20944/preprints202009.0276.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Citral; essential oil; integrated pest management; insect-repellent; lemongrass; MEP pathway; mevalonate pathway
Online: 13 September 2020 (11:30:41 CEST)
REVIEW
|
doi:10.20944/preprints202307.2046.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
CADD; SBDD; LBDD; kinase; small molecule kinase inhibitors
Online: 31 July 2023 (03:05:42 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0636.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
C-terminal Src kinase (CSK), fluorescence resonance energy transfer (FRET), Src family kinase, PTPalpha, submembrane kinase activity
Online: 11 March 2024 (13:29:50 CET)
ARTICLE
|
doi:10.20944/preprints201905.0145.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Sprouty1; proliferation; tyrosine kinase
Online: 13 May 2019 (08:23:54 CEST)
COMMUNICATION
|
doi:10.20944/preprints202011.0174.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
MZA, Manzamine A; CTKD, C-terminal kinase domain; ras-ERK1/2 (extracellular-signal-regulated kinase 1/2) pathway; RSK1, 90kDa ribosomal protein S6 kinase 1; RSK2, 90kDa ribosomal protein S6 kinase 2; NTKD, N-terminal kinase domain
Online: 4 November 2020 (08:27:07 CET)
ARTICLE
|
doi:10.20944/preprints202310.0751.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Drosophila; male meiosis; cyclin B; Cyclin-dependent kinase 1; Cyclin-dependent kinase inhibitors
Online: 12 October 2023 (05:32:28 CEST)
REVIEW
|
doi:10.20944/preprints201808.0044.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast tumor kinase (BRK); protein tyrosine kinase 6 (PTK6); breast cancer; pathways; therapeutics
Online: 2 August 2018 (09:58:55 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0002.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Extracellular calpastatin, Ca2+/ calmodulin (CaM)-dependent protein kinase kinase 2, osteocytes, osteoclasts, bone remodeling
Online: 1 February 2023 (01:11:27 CET)
ARTICLE
|
doi:10.20944/preprints202109.0474.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
NELL2; Preproenkephalin; Endoplasmic reticulum; Calcium ion; Protein kinase C; Extracellular signal-regulated kinase (ERK)
Online: 28 September 2021 (13:40:26 CEST)
COMMUNICATION
|
doi:10.20944/preprints202309.0598.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
macrocycle; quinoxaline; Pim kinases; kinase inhibitor
Online: 11 September 2023 (05:09:07 CEST)
REVIEW
|
doi:10.20944/preprints202305.1789.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
PTK6; Colorectal cancer; Tyrosine Kinase Inhibitors
Online: 25 May 2023 (09:52:24 CEST)
ARTICLE
|
doi:10.20944/preprints201807.0393.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
genetic code expansion, protein kinase B, phosphoinositide dependent kinase 1 (PDK1), phosphoseryl-tRNA synthetase (SepRS), tRNASep
Online: 21 July 2018 (12:35:26 CEST)
REVIEW
|
doi:10.20944/preprints202401.1992.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
MLIP; Cancer; PI3 kinase; Akt; mTOR; Tumorigenesis
Online: 29 January 2024 (05:47:34 CET)
COMMUNICATION
|
doi:10.20944/preprints202312.0083.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
PIM1 protein kinase; hypericin; docking analysis; cancer
Online: 1 December 2023 (11:47:15 CET)
ARTICLE
|
doi:10.20944/preprints202108.0001.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Antitumoral drug; Choline kinase inhibition; Choline uptake
Online: 2 August 2021 (08:42:22 CEST)
REVIEW
|
doi:10.20944/preprints201903.0256.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
immunocheckpoint inhibitors; chemotherapy; tirosin kinase inhibitors; angiogenesis
Online: 28 March 2019 (06:48:37 CET)
ARTICLE
|
doi:10.20944/preprints201703.0215.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
FGFR1; inhibitor; kinase inhibitor; pyrazine; hinge binder
Online: 30 March 2017 (04:13:45 CEST)
ARTICLE
|
doi:10.20944/preprints201908.0177.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
chronic myeloid leukemia; tyrosine kinase inhibitor; adverse drug event; quality of life; second-generation tyrosine kinase inhibitor; nilotinib
Online: 16 August 2019 (08:09:07 CEST)
ARTICLE
|
doi:10.20944/preprints202409.0763.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Epithelial Ovarian Cancer (EOC); Liver Kinase B1 (LKB1); STE20-related Kinase Adaptor Protein (STRAD); Spheroid; Organoid; Mesothelial Clearance; Metastasis
Online: 10 September 2024 (09:00:58 CEST)
REVIEW
|
doi:10.20944/preprints202112.0518.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
B-cell non-Hodgkin lymphoma (B-NHL); B-cell receptor (BCR); Bruton’s tyrosine kinase (BTK); spleen tyrosine kinase (SYK); phosphoinositide-3-kinase (PI3K); ibrutinib; acalabrutinib; copanlisib; idelalisib; umbralisib; fostamatinib; combination therapies
Online: 31 December 2021 (12:23:29 CET)
ARTICLE
|
doi:10.20944/preprints202406.0459.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Protein kinase R, poxviruses, K3L, yatapoxvirus, translational regulation
Online: 7 June 2024 (08:08:13 CEST)
REVIEW
|
doi:10.20944/preprints202406.0069.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Cutaneous T-Cell Lymphoma; kinase inhibitors; targeted therapy
Online: 3 June 2024 (12:13:18 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1746.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
sensitization; adenosine monophosphate-activated protein kinase; metformin; cocaine
Online: 26 October 2023 (18:55:47 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0393.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
poxviruses; protein kinase R; evolution; translational regulation; eIF2
Online: 30 May 2022 (10:42:41 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0115.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
triterpenoids; Acacia stem bark; polypharmacology; protein kinase inhibitors
Online: 3 June 2021 (13:04:47 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0343.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
protein; exercise; muscle damage; creatine kinase; myoglobin; inflammation
Online: 16 July 2020 (06:33:18 CEST)
ARTICLE
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
c-src-tyrosine kinase; QSAR; molecular descriptors; virtual screening; drug discovery; cancer; molecular docking
Online: 25 October 2019 (11:21:43 CEST)
ARTICLE
|
doi:10.20944/preprints201908.0238.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
aurora kinase A; molecular docking; DFT; MD simulation
Online: 23 August 2019 (05:01:40 CEST)
REVIEW
|
doi:10.20944/preprints201809.0435.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Acute Myeloid Leukemia; FLT3; Tyrosine kinase inhibitors; resistance
Online: 21 September 2018 (10:28:34 CEST)
ARTICLE
|
doi:10.20944/preprints201808.0516.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
ALK5 inhibitor; TGF-β; kinase assay; selectivity; docking
Online: 30 August 2018 (05:52:08 CEST)
REVIEW
|
doi:10.20944/preprints202307.0539.v3
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Hepatocellular carcinoma; tyrosine kinase inhibitors; immune checkpoint inhibitors; biomarkers
Online: 17 July 2023 (13:22:33 CEST)
REVIEW
|
doi:10.20944/preprints202306.1643.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
metastasis treatment; small molecules; tyrosine kinase inhibitors; integrins; siRNA
Online: 22 June 2023 (16:10:15 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0538.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Aging; Betaine; dBHMT; Drosophila; dSAMTOR; dTORC1; Kinase; Methionine; SAM
Online: 8 May 2023 (12:06:37 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0634.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
compound 3K; ovarian cancer; pyruvate kinase M2; autophagy; apoptosis
Online: 26 September 2020 (13:34:05 CEST)
COMMUNICATION
|
doi:10.20944/preprints201910.0068.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Frank-Starling; myopathy; Myosin Binding Protein-C; Kinase mechanism
Online: 7 October 2019 (12:15:26 CEST)
ARTICLE
|
doi:10.20944/preprints201901.0018.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
pyruvate kinase M2; prostate cancer; cancer metabolism; mTOR; autophagy
Online: 3 January 2019 (12:32:52 CET)
ARTICLE
|
doi:10.20944/preprints201703.0225.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
acute lung injury; fasudil, Rho kinase; endothelial function; inflammation
Online: 31 March 2017 (08:30:54 CEST)
REVIEW
|
doi:10.20944/preprints202407.0700.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
treatment; biologics; biological drugs; vitiligo; Janus kinase inhibitors (JAKs); cytokines
Online: 9 July 2024 (07:55:45 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1418.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
DENV-2; c-Abl protein kinase; actin; Imatinib; artificial microRNA
Online: 25 March 2024 (06:21:26 CET)
ARTICLE
|
doi:10.20944/preprints202403.0028.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
osmotic stress; glycerol-3-phospate phosphatase; phosphorylation; kinase inhibition; chloroplast
Online: 1 March 2024 (07:48:43 CET)
ARTICLE
|
doi:10.20944/preprints202402.1396.v1
Subject:
Biology And Life Sciences,
Horticulture
Keywords:
diacylglycerol kinase; Actinidia valvata; phylogenetic analysis; waterlogging stress; expression pattern
Online: 23 February 2024 (20:21:46 CET)
ARTICLE
|
doi:10.20944/preprints202402.1157.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
sleep fragmentation; metabolic dysfunction; AMP-activated protein kinase (AMPK); melatonin
Online: 20 February 2024 (15:20:49 CET)
ARTICLE
|
doi:10.20944/preprints202312.0648.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
uterine myoma; Angiopoietin 1; Calcium sensing receptor; Focal Adhesion Kinase
Online: 11 December 2023 (06:03:40 CET)
REVIEW
|
doi:10.20944/preprints202306.0143.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Systemic sclerosis; treatment; Janus kinase inhibitors; fibrosis; anti-cytokine treatment
Online: 2 June 2023 (07:07:00 CEST)
REVIEW
|
doi:10.20944/preprints202207.0024.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
post-translation modifications; CK2; Huntington’s Disease; Kinase Inhibition; HTT phosphorylation
Online: 1 July 2022 (17:47:10 CEST)
COMMUNICATION
|
doi:10.20944/preprints202106.0309.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
mTORC1; RHEB; G-Protein; Allosteric activation; Kinase domain; Binding kinetics
Online: 11 June 2021 (09:14:14 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0174.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Phosphodiesterase (PDE); natural products; inhibitors; Protein Kinase; selectivity; fluorescence polarization
Online: 6 April 2021 (12:07:58 CEST)
REVIEW
|
doi:10.20944/preprints202003.0251.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
gastric acid suppressant; chemotherapy; tyrosine kinase inhibitors; proton pump inhibitors
Online: 31 March 2020 (03:40:46 CEST)
ARTICLE
|
doi:10.20944/preprints201811.0278.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
astrocytes; glutamine; SN1 (SNAT3); Sp1; protein kinase C; ammonia; transport
Online: 12 November 2018 (10:02:12 CET)
REVIEW
|
doi:10.20944/preprints202405.0141.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Arrestin; GPCR; MAP kinase; microtubules; ubiquitin ligase
Online: 5 May 2024 (08:33:01 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1231.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
apoptosis; diaphragm fibrosis; phosphoinositide 3-kinase-g; ventilator-induced diaphragm dysfunction
Online: 18 April 2024 (10:06:43 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1574.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
ALS; Tumor Necrosis Factor-alpha; GDNF; Creatine kinase; ferritin; BM-MSC.
Online: 26 March 2024 (09:15:36 CET)
REVIEW
|
doi:10.20944/preprints202401.0297.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
dual leucine zipper kinase; phosphorylation; protein-protein interaction; proteasomal degradation; palmitoylation
Online: 4 January 2024 (09:32:03 CET)
ARTICLE
|
doi:10.20944/preprints202401.0053.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
oncostatin M; bone morphogenetic protein-4; osteoprotegerin; p70 S6 kinase; osteoblast
Online: 2 January 2024 (09:38:17 CET)
ARTICLE
|
doi:10.20944/preprints202308.1686.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
Schizophrenia; Lactate; Physical exercise; Creatine Kinase (CK); C-Reactive Protein (CRP)
Online: 24 August 2023 (08:20:32 CEST)
REVIEW
|
doi:10.20944/preprints202304.1236.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
FLT3 mutations; resistant/relapsed acute myeloid leukemia; tyrosine kinase inhibitors; gilteritinib
Online: 29 April 2023 (10:55:21 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0525.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Mucormycosis; AlkB; demethylase; virulence; dimorphism; protein kinase A; hyphae development; Mucor
Online: 23 July 2021 (07:57:16 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Kinase Inhibitor; NEK2; Chemoresistance; Avicennia marina; Marine compounds; Molecular docking; Cancer
Online: 7 June 2020 (11:16:35 CEST)
REVIEW
|
doi:10.20944/preprints201907.0256.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
PI 3-kinase; chromosomal instability; PI3K inhibitor; cancer; tumour evolution; centrosome
Online: 23 July 2019 (11:01:34 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0322.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
p21-activated kinase (PAK); Pancreatic ductal adenocarcinoma (PDA); PF-3758309; gemcitabine
Online: 17 September 2018 (15:28:54 CEST)
ARTICLE
|
doi:10.20944/preprints201807.0131.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
pigmentary glaucoma; ROCK kinase inhibitor; RKI-1447; trabecular meshwork; phagocytosis; cytoskeleton
Online: 9 July 2018 (11:27:28 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0034.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
voltage-gated sodium channels; fibroblast growth factors; split luciferase assay; kinase inhibitors
Online: 3 June 2024 (08:07:35 CEST)
ARTICLE
|
doi:10.20944/preprints202312.1162.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
statin; multityrosine kinase inhibitor; sorafenib resistance; hepatocellular carcinoma; lipophilic statin; hydrophilic statin
Online: 15 December 2023 (12:14:20 CET)
COMMUNICATION
|
doi:10.20944/preprints202311.1690.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
serine/threonine protein kinase; amentoflavone; molecular docking; apoptosis
Online: 27 November 2023 (09:09:47 CET)
REVIEW
|
doi:10.20944/preprints202308.0444.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Avenanthramide; AKT-Protein kinase B; Alzheimer's disease; Parkinson's disease; oxidative stress; neuroprotection
Online: 7 August 2023 (02:28:52 CEST)
REVIEW
|
doi:10.20944/preprints202307.0990.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Bruton's tyrosine kinase (BTK); cognitive disorders; multiple sclerosis (MS); Neuroinflammation; immune system
Online: 14 July 2023 (13:24:12 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0156.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
circulating thymidine kinase 1; cell loss; biomarker; early treatment response; breast cancer
Online: 8 September 2021 (16:25:39 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0729.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Gastric cancer; Cyclin-dependent protein kinase; Cluster of differentiation (CD) 47; Prognosis
Online: 31 May 2021 (10:13:20 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0297.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Protein Kinase Receptor (PKR); Mammarenavirus; Interferon; Innate immune response; Mx1; ISG15; CCL5
Online: 13 May 2021 (13:27:07 CEST)
ARTICLE
|
doi:10.20944/preprints201708.0015.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
ischemia-reperfusion injury (IRI), ω3-PUFA, AMP-activated protein kinase (AMPK), autophagy
Online: 4 August 2017 (12:56:08 CEST)
ARTICLE
|
doi:10.20944/preprints201611.0121.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
tissue microarray; immunohistochemistry; cancer imaging; tyrosine kinase receptor; normal tissue; colon cancer
Online: 24 November 2016 (11:07:23 CET)
REVIEW
|
doi:10.20944/preprints201912.0412.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Frank-Starling; angiotensin receptor; muscle contraction; myosin light chain kinase; Protein Kinase C-βII; myosin light chain phosphatase; β-arrestin; MgATP; MgADP-phosphomyosin; myosin LC affinity for Ca2+
Online: 11 January 2020 (13:24:08 CET)
ARTICLE
|
doi:10.20944/preprints202407.0524.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
phyllotaxis; stem thickness; BELLRINGER transcription factor; replum; vascular bundles; ROP GTPase-activated kinase
Online: 9 July 2024 (06:03:33 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1174.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Gastric cancer; Proto-Oncogene Protein c-met; Tyrosine Kinase Inhibitors; Cell Line; Tumor
Online: 17 May 2024 (12:28:09 CEST)
REVIEW
|
doi:10.20944/preprints202403.0254.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
dichloroacetate; cancer; lactic acidosis; glioma; pyruvate dehydrogenase kinase; pyruvate dehydrogenase; pyruvate dehydrogenase phosphatase
Online: 5 March 2024 (13:03:15 CET)
ARTICLE
|
doi:10.20944/preprints202312.0595.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
chronic myeloid leukemia; tyrosine kinase inhibitor; very elderly; safety; efficacy; outcome; dose optimization
Online: 8 December 2023 (10:26:16 CET)
ARTICLE
|
doi:10.20944/preprints202311.0790.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
Plasmodium falciparum, infection, erythrocyte, pyruvate kinase deficiency, enzymopathy, 2,3-bisphosphoglycerate, transcriptome, Nanopore technology
Online: 13 November 2023 (09:02:00 CET)
ARTICLE
|
doi:10.20944/preprints202307.1689.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
N-acetyl-L-glutamate kinase; arginine biosynthesis; PII- signal transduction protein; green algae
Online: 25 July 2023 (11:43:42 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1297.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Heart failure; β-adrenergic receptor; cardiac fibrosis; cardiac inflammation; Bruton’s tyrosine kinase; Zanubrutinib
Online: 19 June 2023 (05:23:12 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1059.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
corneal enendothelial dystrophy; Slc4a11; barrier function; lactate transporters; Src kinase; oxidative stress; Visomitin
Online: 15 May 2023 (15:50:03 CEST)
ARTICLE
|
doi:10.20944/preprints202211.0356.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Focal adhesion kinase; 3D-QSAR; Molecular Dynamics; MM-PB/GBSA; Free energy perturbation
Online: 18 November 2022 (10:13:00 CET)
BRIEF REPORT
|
doi:10.20944/preprints202207.0144.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Protein Kinase C; PKCeta; autophagy; senescence; chemoresistance; oxidative stress; ER stress; 3MA; chloroquine
Online: 10 July 2022 (06:42:23 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0349.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
MAP kinase; ERK5; Bmk1; SUMO; nuclear translocation; transcription; cell proliferation; cancer; Hsp90; Cdc37
Online: 29 January 2020 (05:00:39 CET)
REVIEW
|
doi:10.20944/preprints202407.1534.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
lymphoma; B‐cell; hematologic neoplasms; bruton tyrosine kinase; protein kinase inhibitors; drug resistance; neoplasm; ibrutinib; pirtobrutinib; molecular targeted therapy; chronic lymphocytic leukemia; hematopoietic stem cell transplantation; covalent inhibitors; protein degradation
Online: 18 July 2024 (17:24:05 CEST)
ARTICLE
|
doi:10.20944/preprints202408.1642.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
allogeneic hematopoietic stem cell transplantation; chronic myeloid leukaemia; tyrosine kinase inhibitors; imatinib; dasatinib; nilotinib
Online: 22 August 2024 (16:30:22 CEST)
ARTICLE
|
doi:10.20944/preprints202408.0379.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
biocatalysis; ATP regeneration; polyphosphate; polyphosphate kinase; cofactor recycling; cascade reactions; Burkholderia cenocepacia
Online: 6 August 2024 (07:03:48 CEST)
REVIEW
|
doi:10.20944/preprints202312.0095.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Eosinophilia,; hematological neoplasm; myeloid/lymphoid neoplasm with eosinophilia; tyrosine kinase fusion genes; acute leukemia
Online: 1 December 2023 (16:34:12 CET)
ARTICLE
|
doi:10.20944/preprints202309.1199.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
protein-protein interaction; fragment molecular orbital method; polo-like kinase 1; molecular dynamics simulation
Online: 19 September 2023 (03:58:32 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0108.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Plasmodium; malaria; type III beta phosphatidylinositol 4-kinase; virtual screening; homology modeling; molecular dynamics
Online: 5 November 2021 (08:44:31 CET)
REVIEW
|
doi:10.20944/preprints202103.0510.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RAF kinase independent; RAS; MST2; ASK; PLK; RHO-α; apoptosis; cell cycle; cancer therapy
Online: 22 March 2021 (10:29:37 CET)
ARTICLE
|
doi:10.20944/preprints202009.0251.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Trichoderma atroviride; mycoparasitism; secondary metabolites; 6-pentyl-alpha-pyrone; Tmk3 MAP kinase; light; dark
Online: 11 September 2020 (08:49:15 CEST)
REVIEW
|
doi:10.20944/preprints201902.0245.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cyclin-dependent kinases; cyclin-dependent kinase 4 and 6 inhibitors; targeted therapies; breast cancer
Online: 27 February 2019 (04:48:54 CET)
REVIEW
|
doi:10.20944/preprints201809.0360.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
p-21 activated kinase; pioglitazone, metformin, type 2 diabetes mellitus, cancer, chemoprevention, and inflammation.
Online: 19 September 2018 (00:50:05 CEST)
REVIEW
|
doi:10.20944/preprints201808.0403.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
p-21 activated kinase; pioglitazone, metformin, type 2 diabetes mellitus, cancer, chemoprevention, and inflammation.
Online: 23 August 2018 (05:10:55 CEST)
ARTICLE
|
doi:10.20944/preprints201802.0026.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
pig eye perfusion model; pigmentary glaucoma; ocular hypertension; ocular hypotension; phagocytosis; rho-kinase inhibitor
Online: 5 February 2018 (03:39:57 CET)
REVIEW
|
doi:10.20944/preprints201705.0212.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
cancer; cell-surface receptor; EGFR; molecular mechanism; phosphorylation; receptor tyrosine kinase; transmembrane signal transduction
Online: 30 May 2017 (08:34:04 CEST)
COMMUNICATION
|
doi:10.20944/preprints202410.1074.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Polo-like-kinase-1; RNA-seq mRNA expression; prostate cancer; prognostic marker; ORIEN database
Online: 14 October 2024 (15:42:26 CEST)
REVIEW
|
doi:10.20944/preprints202409.1641.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Chronic Myeloid Leukemia; Bone Mineral Density; Bone Turnover; Tyrosine Kinase Inhibitor; CTX-1; Osteocalcin; Imatinib
Online: 20 September 2024 (15:06:17 CEST)
ARTICLE
|
doi:10.20944/preprints202407.2128.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
metastatic renal cell carcinoma; tyrosine kinase inhibitor sunitinib; nomogram; cancer-specific survival; prognosis; treatment response
Online: 26 July 2024 (06:23:32 CEST)