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Preprint ARTICLE | doi:10.20944/preprints201608.0141.v1

Vorinostat Pretreatment Enhanced Ciprofloxacin-Induced Antibacterial Activity

Majed M. Masadeh, Karem H. Alzoubi, Sayer I. Al-azzam, Ahlam M. Al-buhairan

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: ciprofloxacin; MIC; vorinostat; antimicrobial susceptibility

Online: 13 August 2016 (11:05:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0891.v1

Susceptibility Trends of Respiratory and Enteric Porcine Pathogens to Last Resource Antimicrobials

Anna Vilaro, Elena Novell, Vicens Enrique-Tarancon, Jordi Baliellas, Lourdes Migura-Garcia, Lorenzo Fraile

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: trend analysis; antimicrobial susceptibility; porcine pathogens

Online: 14 September 2023 (03:40:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints202004.0241.v2

Epigenetic Regulation Mediated by microRNAs in the Susceptibility and Pathogenesis of Rheumatoid Arthritis

Shicheng Guo, Cen Chang, Lingxia Xu, Runrun Zhang, Yehua Jin, Momiao Xiong, Dongyi He

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: rheumatoid arthritis; miRNA; susceptibility; pathogenesis; epigenetics

Online: 22 April 2020 (05:52:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0078.v1

Susceptibility Analysis of COVID-19 in Smokers Based on ACE2

Jin Wang, Qiulin Luo, Rui Chen, Tao Chen, Jianxiang Li

Subject: Biology And Life Sciences, Behavioral Sciences Keywords: cigarette smoke; ACE2; HCoV-19; susceptibility

Online: 5 March 2020 (03:15:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.0064.v1

New Associations with HIV Predisposing and Protective Alleles of the HLA System in a Peruvian Population

Daisy Obispo, Oscar Acosta, Maria Guevara, Susan Echavarria, Susan Espetia, Maria Dedios, Carlos Yábar, Ricardo Fujita

Subject: Biology And Life Sciences, Virology Keywords: HIV; HLA genes; WES; susceptibility; Peruvian population

Online: 1 October 2024 (13:03:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0031.v1

Whole-Genome Sequencing, Phenotypic Characterization, and Antifungal Susceptibility Profiles of Three Aspergillus hortae Clinical Isolates from Colombia

Santiago Marín-Carvajal, Mariana Quiceno-Torres, Maria Camila Zuleta, Susana Torres, Álvaro Leon Rúa, Ana Maria García, Clayton Luiz Borges, Angela Maria López, Juan Guillermo McEwen, Orville Hernandez Ruiz, Oscar Mauricio Gómez

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Aspergillus hortae; Genome; Pathogenic fungi; antifungals susceptibility

Online: 2 September 2024 (12:27:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0066.v1

Information Value Model Based Mapping of Updated Spatial and Temporal Landslide Susceptibility: A Case Study from East Sikkim District, India’s Northeastern Himalayas

Md Fariduddin Rafique, Varun Joshi

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: East Sikkim; Landslide susceptibility; Information Value Model

Online: 2 April 2024 (12:48:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202311.1170.v1

Pluvial Flood Susceptibility in the Local Community of the City of Gospić (Croatia)

Silvija Šiljeg, Rina Milosevic, Marica Mamut

Subject: Environmental And Earth Sciences, Geography Keywords: Susceptibility; Pluvial flood; Risk perception; Local community

Online: 21 November 2023 (10:30:05 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1009.v1

Tailoring Rheumatoid Arthritis Treatment through a Gender Lens

Loreto Carmona, Elena Aurrecoechea, Maria Jesus Garcia-Yebenes

Subject: Medicine And Pharmacology, Other Keywords: rheumatoid arthritis; gender; sex; susceptibility; treatment effect

Online: 16 November 2023 (03:06:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.0361.v1

Characterization of Listeria monocytogenes in Palermo (Sicily, Italy) from 2018 to 2020: Correlation between Molecular and Clinical Data

Maria Rita Tricoli, Chiara Massaro, Ignazio Arrigo, Teresa Fasciana, Orazia Diquattro, Francesca Di Bernardo, Elena Galia, Mario Palermo, Anna Giammanco

Subject: Public Health And Healthcare, Other Keywords: Listeria monocytogenes; serogroup; MLST; MVLST; antibiotic susceptibility

Online: 6 November 2023 (15:07:54 CET)

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Preprint REVIEW | doi:10.20944/preprints202108.0276.v1

Antifungal Combinations in Dermatophytes

Lucia Brescini, Simona Fioriti, Gianluca Morroni, Francesco Barchiesi

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: dermatophytes; antifungals; antifungal susceptibility testing; drug combination

Online: 12 August 2021 (13:16:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201904.0028.v1

GIS-Based Rockfall Susceptibility Zoning in Greece

Charalampos Saroglou

Subject: Engineering, Civil Engineering Keywords: rockfall; susceptibility; GIS; rainfall; earthquake; fault; inventory

Online: 2 April 2019 (07:54:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.1263.v2

A Method to Reverse Epimutations

Steven Olsen

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: Homeostasis; HDEC; Hormesis; Epimutations; Susceptibility; Toxicogenomics

Online: 17 September 2024 (05:04:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1151.v1

Exploring Virulence Factors and Antifungal Susceptibility in Sporothrix Isolates: A Comparative Study between Feline and Human Hosts

Blenda Fernandes, Rachel Basques Caligiorne, Thais Almeida Marques da Silva, Maiara Miranda Campolina, Emanoelle Rodrigues Rutren La Santrer, Iara Furtado Santiago, Claudia Barbosa Assunçao, Keterlly Silva Mota de Souza, Aline Dias Valerio, Sonia Maria de Figueiredo, Susana Johann

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Sporothrix; sporothricosis; virulence profile; antifungal susceptibility; species identification.

Online: 17 May 2024 (05:43:32 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202402.1691.v1

Central Line-Associated Bloodstream Infection Due to Elizabethkingia anophelis: Case Report and Literature Review on Pediatric Infections

Sophia Maraki, Nikolaos Katzilakis, Ioannis Neonakis, Dimitra Stafylaki, Viktoria Eirini Mavromanolaki, Ioannis Kyriakidis, Iordanis Pelagiadis, Eftychia Stiakaki

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Elizabethkingia anophelis; pediatric infections; neonate; identification; antimicrobial susceptibility

Online: 29 February 2024 (10:38:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1854.v1

Land Subsidence Susceptibility Mapping in Ca Mau Province, Vietnam Using Boosting Models

Anh Van Tran, Maria Antonia Brovelli, Khien Trung Ha, Dong Thanh Khuc, Duong Nhat Tran, Hanh Hong Tran, Nghi Thanh Le

Subject: Environmental And Earth Sciences, Geography Keywords: AdaBoost; Gradient Boosting; XGBoost; Ca Mau; Subsidence susceptibility

Online: 26 January 2024 (07:00:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.0403.v1

Phase-Dependent Differential In Vitro and Ex Vivo Susceptibility of Aspergillus flavus and Fusarium keratoplasticum to Azole Antifungals

Darby Roberts, Jacklyn Salmon, Marc A Cubeta, Brian C Gilger

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Aspergillus; Fusarium; fungal keratitis; antifungal susceptibility; MIC; azole

Online: 6 September 2023 (10:33:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0428.v1

The Influence of Selected Soil Parameters Modified With Sewage Sludge and Fly Ash Fertilization on the Total Number of Bacteria (TNB) and Bradyrhizobium Species at Soybean Agroecosystem

Izabella Pisarek, Katarzyna Grata

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: soybean agroecosystem; Bradyrhizobium species; magnetic susceptibility; humic substances.

Online: 22 December 2022 (11:37:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202207.0046.v1

Trends in Infectious Keratitis in Taiwan: An Update on Predisposing Factors, Microbiological and Antibiotic Susceptibility Patterns

Jin-Jhe Wang, Chien-Hsiung Lai, Chau-Yin Chen, Chia-Yen Liu, Meng-Hung Lin, Yao-Hsu Yang, Pei-Lun Wu

Subject: Medicine And Pharmacology, Ophthalmology Keywords: infectious keratitis; corneal infection; antibiotic susceptibility; antimicrobial resistance

Online: 4 July 2022 (09:41:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202202.0318.v1

Hypnotizability-Related Cerebral Blood Flow

Anas Rashid, Enrica Laura Santarcangelo, Silvestro Roatta

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: doppler; NIRS; hyperventilation; rebreathing; cognitive tasks; hypnotic susceptibility

Online: 24 February 2022 (16:51:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202112.0115.v2

Disconnect between Published AC Magnetic Susceptibility of a Room Temperature Superconductor and Measured Raw Data

Jorge E Hirsch

Subject: Physical Sciences, Condensed Matter Physics Keywords: room temperature superconductivity; magnetic susceptibility; diamagnetism; raw data

Online: 31 December 2021 (10:13:20 CET)

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Preprint SHORT NOTE | doi:10.20944/preprints202112.0188.v2

Incompatibility of Published ac Magnetic Susceptibility of a Room Temperature Superconductor with Measured Raw Data

J. E. Hirsch

Subject: Physical Sciences, Condensed Matter Physics Keywords: hydride superconductor; room temperature superconductor; pressure; diamond anvil cell; ac magnetic susceptibility; raw data; background signal; random noise

Online: 21 December 2021 (09:00:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202111.0140.v1

Molecular Typing and Antimicrobial Susceptibility Profiles of Streptococcus uberis Isolated From Sheep Milk

Nives Maria Rosa, Ilaria Dupre, Elisa Azara, Carla Maria Longheu, Sebastiana Tola

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Streptococcus uberis; mastitis; typing; antimicrobial susceptibility; resistance genes

Online: 8 November 2021 (13:12:44 CET)

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Intrammary infections are a major problem for dairy sheep farms, and Streptococcus uberis is one of the main etiological agents of ovine mastitis. Surveys on antimicrobial resistance are still limited in sheep and characterization of isolates is important for acquiring information on resistance and for optimizing therapy. In this study, a sampling of 124 S. uberis isolates collected in Sardinia (Italy) from sheep milk was analysed by multilocus-sequence typing (MLST) and pulsed field gel electrophoresis (PFGE) for genetic relatedness. All isolates were also subjected to antimicrobial susceptibility analysis by the disk diffusion test using a panel of 14 antimicrobials. Resistance genes were detected by PCR assays. MLST analysis revealed that the isolates were grouped into 86 sequence types (STs), of which 73 were new genotypes, indicating a highly diverse population of S. uberis. The most frequently detected lineage was the clonal complex (CC)143, although representing only 13.7% of all characterized isolates. A high level of heterogeneity was also observed among the SmaI PFGE profiles, with 121 unique patterns. Almost all (96.8%) isolates were resistant to at least one antimicrobial, while all exhibited phenotypic susceptibility to oxacillin, amoxicillin-clavulanic acid and ceftiofur. Of the antimicrobials tested, the highest resistance rate was found against streptomycin (93.5%), kanamycin (79.8%) and gentamicin (64.5%), followed by novobiocin (25%) and tetracycline-TE (19.3%). Seventy-four (59.7%) isolates were simultaneously resistant to all aminoglycosides tested. Seventeen isolates (13.7%) exhibited multidrug resistance. All aminoglycosides-resistant isolates were PCR negative for aad-6 and aphA-3’ genes. Among the TE-resistant isolates, the tetM gene was predominant, indicating that the resistance mechanism is mainly mediated by the protection of ribosomes and not through the efflux pump. Three isolates were resistant to erythromycin, and two of them harboured the ermB gene. This is the first study reporting a detailed characterization of the S. uberis strains circulating in Sardinian sheep. Further investigations will be needed to understand the relationships between S. uberis genotypes, mastitis severity, and intra-mammary infection dynamics in the flock, as well as to monitor the evolution of antimicrobial resistance.

Preprint ARTICLE | doi:10.20944/preprints202109.0095.v1

Selective Breeding for Disease Resistant PRNP Variants to Manage Chronic Wasting Disease in Farmed Whitetail Deer

Nicholas Haley, Rozalyn Donner, Kahla Merrett, Matthew Miller, Kristen Senior

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: prion; deer; PRNP; selective breeding; resistance; susceptibility; CWD

Online: 6 September 2021 (13:13:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0704.v1

Analysis of Susceptibility to Slope Movements in the Environment of Road Infrastructures. Models for Obtaining Predictive Mapping Applied to Roads in the Provinces of Malaga and Granada (Spain)

María J. Perles-Roselló, Santiago Pardo-García, Juan F. Sortino-Barrionuevo, Sergio Reyes-Corredera, Claudio Puglisi

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Road infrastructures; risk; slope movements; cartography of susceptibility.

Online: 29 June 2021 (12:53:55 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202009.0115.v1

Molecular Typing and Antimicrobial Susceptibility Profile of Staphylococcus aureus Isolates Recovered from Bovine Mastitis and Nasal Samples

Renata P. Santos, Fernando N. Souza, Ana Claudia C. Oliveira, Antônio F. de Souza Filho, Juliana Aizawa, Luisa Z. Moreno, Adriano F. da Cunha, Adriana Cortez, Alice M. M. P. Della Libera, Marcos B. Heinemann, Mônica M. O. P. Cerqueira

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: intramammary infection; spa typing; antimicrobial susceptibility; dairy cow

Online: 5 September 2020 (04:51:45 CEST)

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Working Paper REVIEW

Evidences from a Systematic Review and Meta-analysis Unveil the Role of miRNA Polymorphisms in the Predisposition to Female Neoplasms

Milad Bastami, Jalal Choupani, Zahra Saadatian, Sepideh Zununi Vahed, Elaheh Ouladsahebmadarek, Yasser Mansoori, Abdolreza Daraei, Hossein Samadi Kafil, Bahman Yousefi, Mahdi Mahdipour, Andrea Masotti, Ziba Nariman-Saleh-Fam

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: microRNA; polymorphism; breast neoplasm; female neoplasm; susceptibility; cancer

Online: 25 September 2019 (10:14:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0363.v1

Diamagnetism of Bulk Graphite Revised

Bogdan Semenenko, Pablo Esquinazi

Subject: Physical Sciences, Condensed Matter Physics Keywords: graphite; diamagnetism; thickness dependence; susceptibility; interfaces; conductivity; graphene

Online: 16 October 2018 (13:56:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201807.0220.v1

Synthesis, Growth and Optical Properties of 2-Aminopyridine Potassium Di-hydrogen Orthophosphate Crystal in Additive of Cadmium Chloride and Lithium Chloride

D. Sivavishnu, R. Srineevasan, J. Johnson

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: Synthesis, Crystal growth, Optical band gap, electrical susceptibility.

Online: 12 July 2018 (15:56:11 CEST)

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Preprint REVIEW | doi:10.20944/preprints202312.1446.v1

The Escalating Specter of Antifungal Resistance in Superficial Mycoses

Ahmed Kadry Eltokhy, Ali Mohamed El-Abbasi, Mohamed Kadri Eltoukhi, Sidi Mohammed lahbib Seddiki, Mahmoud Afif Ghannoum

Subject: Medicine And Pharmacology, Dermatology Keywords: Antifungal resistance; superficial mycoses; antifungal susceptibility; Terbinafine resistant Trichophyton

Online: 19 December 2023 (15:57:37 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.1149.v1

Artificial Intelligence in MALDI-TOF MS: Microbial Identification, Strain Typing, and Antimicrobial Resistance Detection

Hsin-Yao Wang, Chia-Ru Chung, Wan-Ying Lin, Sriram Kalpana, Jorng-Tzong Horng, Tzong-Yi Lee, Jang-Jih Lu

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: artificial intelligence; antimicrobial susceptibility testing; antimicrobial typing; MALDI-TOF

Online: 15 December 2023 (08:57:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1540.v1

Investigation of Phishing Susceptibility with Explainable Artificial Intelligence

Zhengyang Fan, Wanru Li, Kathryn Blackmond Laskey, Kuo-Chu Chang

Subject: Social Sciences, Psychology Keywords: Phishing Susceptibility; Cyber Security; Interpretable Artificial Intelligence; Machine Learning

Online: 24 November 2023 (02:42:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202306.2075.v1

Geological Disaster Susceptibility Evaluation of Random Forest Weighted Deterministic Coefficient Model

Shaohan Zhang, Shucheng Tan, Jinxuan Zhou, Yongqi Sun, Duanyu Ding, Jun Li

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: geological hazard; susceptibility; random forests; certainty factor; Huize county

Online: 29 June 2023 (08:27:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.2212.v1

Group B Streptococci Recto-Vaginal Colonization, Antimicrobial Susceptibility Pattern and Associated factors among Pregnant Women at Selected Health Facilities of Wolaita Sodo Town, Southern Ethiopia

Abera Kumalo Shano, Biruk Gebre Takele, Shimelis Shiferaw Jejaw, Wokil Wolde Dana, Tamirayehu Shonde Jagiso

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: GBS; Antibiotic susceptibility pattern; pregnant women; Wolaita Sodo; Ethiopian

Online: 2 June 2023 (04:53:16 CEST)

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Background: Streptococcus agalactiae or Group B Streptococcal colonization of the gastrointestinal and genital tracts of pregnant women usually remains asymptomatic; even if it is the critical determinant of infection in neonates and young infants. It causes early and late onset of invasive Group B Streptococcus (GBS) disease manifesting as septicemia, meningitis and pneumonia. Now it is recognized as an important cause of maternal and neonatal morbidity and mortality in many parts of the world including Ethiopia where the magnitude of the problem has been little studied. The aim of this study was to assess the prevalence of GBS colonization, to identify associated risk factors and antimicrobial susceptibility pattern among pregnant women at selected health facilities of Wolaita Sodo Town, Southern Ethiopia. Methodology: A health facility based cross-sectional study design was conducted at WSUCSH & Wolaita Sodo Health Center from June to August, 2022. A total of 279 pregnant women who were in ANC follow up with at 35-37 weeks of gestation were included. For GBS isolation, recto-vaginal swabs were inoculated in 1ml Todd-Hewitt broth medium supplemented with 10μg/ml colistin and 15μg/ml nalidixic acid and followed by identification of isolates based on colonial morphology, gram stains, catalase reaction and CAMP tests. Antimicrobial susceptibility testing was performed using modified Kirby–Bauer disk diffusion method. All collected data were organized in Epi info 4.6.0.2, then transfer tabulated using SPSS version 20. Logistic regression analysis was used to see the association between variables. Finally, the p-value < 0.05 were considered statistically significant. Results: In present study, 279 pregnant mothers included and their age was between 15 to 38 years with a mean of 26.5 ± 4.5 years. Of all participants, the highest 120 (43.01%) were housewives. The overall carriage rate of GBS was 67(24.0%). GBS colonization showed a statistically significant association with college and above levels of maternal education [AOR= 6.610, 95% CI (1.724 - 25.349), P=0.01]. High susceptibility of GBS isolate was seen to Penicillin G & Chloramphenicol (92.5%) for each, Ampicillin, and Ceftriaxone (89.6%) each, following Vancomycin (74.62%), and Erythromycin (77%). Relatively, GBS showed high resistance to Tetracycline (88 %). Conclusion: In this study, the overall prevalence of GBS colonization was 24.0%. College and above educational level was statistically significant with GBS colonization. This study used to give attention to the management of pregnant women by making GBS culture one of the routine diagnoses during ANC follow-up and to prevent infection by early detection.

Preprint ARTICLE | doi:10.20944/preprints202303.0277.v1

Spatial Prediction of Landslide using Hybrid Multi-Criteria Decision-Making Methods: A Case Study, Saqqez-Marivan Mountain Road

Himan Shahabi, Rahim Tavakolifar, Mohsen Alizadeh, Sayed M. Bateni, Mazlan Hashim, Ataollah Shirzadi, Effi Helmy Ariffin, Isabelle D. Wolf, Saman Shojae Chaeikar

Subject: Environmental And Earth Sciences, Geography Keywords: Landslides; inventory; susceptibility; fuzzy TOPSIS; ROC curve; Iran ;

Online: 15 March 2023 (09:19:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202210.0286.v1

Interleukin 6 and Interferon Gamma Haplotypes Are Related to Cytokine Serum Levels in Dogs in an Endemic Leishmania infantum Region

Luis Álvarez, Pilar Rentero-Garrido, Pablo-Jesús Marín-García, Lola Llobat

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: cytokines; haplotypes; immune response; Leishmania; regulatory mechanisms; resistance; susceptibility

Online: 19 October 2022 (11:30:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0350.v1

Using the Vertical Distribution of Magnetic Susceptibility in the Assessment of Soil Condition in the Krakow Area, Southern Poland

Anna Wojas

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: magnetic susceptibility; soil magnetometry; vertical profiles; soil contamination; Krakow

Online: 25 July 2022 (05:36:35 CEST)

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The paper concerns the distribution of apparent magnetic susceptibility in soil profiles located in the areas of topsoil magnetic susceptibility anomalies in Krakow. The type of land use, possible sources of magnetic carriers, and the type of soil were taken into account. Additionally, at each soil profile, a comparison between soil magnetic susceptibility and the results of geochemical analyzes of soil samples was made. The study shows very characteristic changes in magnetic susceptibility with depth, reflecting the interdependencies between natural and anthropogenic factors. A visible magnetic susceptibility maximum at the depth of 10-30 cm is observed at each soil profile. The maximum is associated mainly with the deposition of atmospheric dust and its vertical range depends on the level of anthropopression and natural conditions of soils. At the depth above 40 cm in the eastern part of Krakow, a correlation between the magnetic susceptibility and the soil type (chernozems de-veloped on loess) was found. All indicates that the thicknesses of contaminated upper horizons are not accidental and they depend on human interactions with the environment and the type of soil. An attempt at template establishment with the sources of magnetic particle carriers for different places in the city was made. As the result, in high urbanized sites, the extreme values of magnet-ic susceptibility rapidly change in short vertical distances can identify the richness of anthropo-genic layers with various types of anthropogenic ferrous material and/or additionally Fe-carrying objects buried in soils. In industrialized sites, anthropogenic input plays the most important role in the creation of soil magnetic characteristics. What is more, industrial pollution hides the natural magnetic properties of chernozems. In opposite, the studies at the sites under low anthropopression (mainly located in forests) allow for better insight into magnetic proper-ties arising during pedogenic processes, indirectly giving information about soil conditions. In the forest areas, the lowest values of soil magnetic susceptibility were measured. Additionally, the influence of pedogenic and lithogenic factors on forest soils is manifested in the results. Among the sites concerned, particular attention should be paid to the vicinity of the steel plant because of the agricultural land in the surroundings.

Preprint ARTICLE | doi:10.20944/preprints202009.0089.v1

Antimicrobial Resistance Genes in Porcine Pasteurella Multocida are not Associated with its Antimicrobial Susceptibility Pattern

Máximo Patrocchi-Rilo, César-B. Gutiérrez-Martín, Esther Pérez-Fernández, Anna Vilaró, Lorenzo Fraile, Sonia Martínez-Martínez

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Pasteurella multocida; antimicrobial resistance genes; antimicrobial susceptibility patterns; swine

Online: 4 September 2020 (07:47:26 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints201910.0166.v1

In Vitro Benznidazole and Nifurtimox Susceptibility Profile of Trypanosoma cruzi Strains Belonging to Discrete Typing Units TcI, TcII and TcV

Suzana Revollo, Bruno Oury, Andrea Vela, Michel Tibayrenc, Denis Sereno

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Chagas Disease; Trypanosoma cruzi; benznidazole; nifurtimox; antimicrobial susceptibility test

Online: 15 October 2019 (08:26:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201902.0115.v1

Susceptibility of Exopalaemon carinicauda to the Infection with Shrimp Hemocyte Iridescent Virus

Xing Chen, Liang Qiu, Hailiang Wang, Peizhuo Zou, Xuan Dong, Fuhua Li, Jie Huang

Subject: Biology And Life Sciences, Virology Keywords: Shrimp hemocyte iridescent virus; Exopalaemon carinicauda; susceptibility; host; ISDL

Online: 13 February 2019 (13:06:15 CET)

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In this study, ridgetail white prawns Exopalaemon carinicauda were infected per os with debris of Shrimp hemocyte iridescent virus (SHIV)-infected Penaeus vannamei and via intramuscular injection (im) with raw extracts of SHIV. The infected E. carinicauda showed obvious clinical symptoms, including weakness, empty gut and stomach, pale hepatopancreas, and partial death with cumulative mortality of (50.0±26.5)% and (76.7±18.3)%, respectively. Results of TaqMan probe based real-time quantitative PCR showed that the moribund and survival individuals with clinical signs of infected E. carinicauda were SHIV-positive. Histological examination showed that there were dark eosinophilic inclusions, of which some were surrounded with or contained tiny basophilic staining, and pyknosis in cytoplasm of hemocytes in the hepatopancreatic sinus, hematopoietic cells, and cuticular epithelium, etc. Positive hybridization signals were observed in stomach, hematopoietic tissue, cuticular epithelium, and hepatopancreatic sinus of infected prawns from both per os and im groups, according to the results of in situ DIG-labeling-loop-mediated DNA Amplification (ISDL). Transmission electron microscopy of ultrathin sections showed that icosahedral SHIV particles existed in hepatopancreatic sinus and gills of the infected E. carinicauda of the per os group. The viral particles were also observed in the hepatopancreatic sinus, gills, pereiopods, muscles, and uropods of the infected E. carinicauda from the im group. The assembled virions mostly distributed outside of the assembling area near cellular membrane of infected cells, which were with envelope and about 150 nm in diagonal diameter. The results of molecular biological tests, histopathological examination, ISDL, and transmission electron microscopy confirmed that E. carinicauda is one of the susceptible hosts of SHIV. This study also reminded that E. carinicauda showed some degree of tolerance to the infection with SHIV per os challenge mimicking natural pathway.

Preprint ARTICLE | doi:10.20944/preprints202409.0603.v1

The Time Course of Catecholamine Dose Reduction in Septic Shock as a Predictor of Bacterial Susceptibility to Empiric Antimicrobial Therapy: A Retrospective Observational Study

Tsukasa Kuwana, Kosaku Kinoshita, Yurina Yamaya, Ken Takahashi, Junko Yamaguchi, Atsushi Sakurai, and Toru Imai

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: antimicrobial susceptibility; catecholamines; early indicator; norepinephrine equivalent (NEE); septic shock

Online: 9 September 2024 (12:37:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0529.v1

MMS19 and IFIH1 Host Genetic Variants Associate with SARS-CoV-2 Infection in Elderly Residents of Long-Term Care Facilities

Sandra Franco, Macedonia Trigueros, Dolors Palacín, Josep Maria Bonet-Simó, Maria del Mar Isnard, Nemesio Moreno, Lourdes Mateu, Nuria Prat, Marta Massanella, Miguel Angel Martinez

Subject: Biology And Life Sciences, Aging Keywords: SARS-CoV-2; Infection susceptibility; Host genetics; Elderly; COVID-19

Online: 5 July 2024 (12:06:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0494.v1

Assessing Herbicide Efficacy and Susceptibility for Weed Management and Enhancing Production of Non-GMO Soybean Cultivation

Muhammad Awais Arshad, Rana Nadeem Abbas, Abdul Khaliq, Zaheer Ahmed

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Susceptibility index, soybean, weed management, herbicides, crop yield, agriculture, Pakistan.

Online: 8 April 2024 (10:15:09 CEST)

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Soybean (Glycine max L.) is a vital leguminous crop known for its rich nutritional profile, includ-ing high protein and oil content, making it a valuable resource in global agriculture and human nutrition. In Pakistan due to regulatory issues non-GMO soybean is grown therefore, the universal herbicide control method is not applicable. Similarly, for other crops, specific herbicides are avail-able but for soybean no crop specific herbicide is present. A comprehensive study was conducted over two growing seasons, in 2022 and 2023, at Agronomic Research Farm University of Agri-culture Faisalabad. The research involved 16 different treatments, including both six pre-emergence and eight post-emergence herbicides as well as a control group and weedy check. Findings of this study showed that critical importance of weed management in soybean cultiva-tion, as unchecked weed infestation can lead to substantial yield losses. Among the pre-emergence herbicide S-Metolachlor + Pendimethalin performed best and showed higher plant height (54.33 cm & 53.67 cm), 100 grain weight (11.57 g & 12 g), seed yield plant-1 (13.07 g and 12.87 g), lower Susceptibility Index (10%), higher weed control percentage (91.21% & 95.65%) higher weed con-trol efficiency (92.02% & 93.43%), herbicide efficiency index (27.54% & 32.48%) and lower weed index (18.16% & 21.70%) during 2022 and 2023 respectively. However, in post emergence herbi-cide the Fluizefop-p-butyl is most effective herbicide due to less crop injury 10% Susceptibility In-dex, higher plant height (42.67 cm & 44 cm), whole plant weight (93.33 g & 95 g), 100-grain weight (11.40 g & 11.77 g), seed yield plant-1 (12.87 g & 13.13 g), higher weed control percentage (91.12% & 91.03%) higher weed control efficiency (89.73% & 92.36%, herbicide efficiency index (21.18% & 30.41%) and lower weed index (19.42% & 20.08%) in both 2022 and 2023 respectively. Notably, herbicides such as S-Metolachlor + Atrazine + Mesotrione, Topramezone, Mesosulfu-ron-methyl + Iodosulfuron-methyl sodium and Mesotrione + Atrazine led to complete plant mor-tality, resulting lethal to soybean. The findings of this study support the hypothesis that screened the best suitable herbicides with less plant injury, and higher efficiency index. So, it is recom-mended that the application of S-Metolachlor + Pendimethalin as PRE and Fluizefop-p-butyl as POST showed the least injury and best weed control results with higher grain yield.

Preprint ARTICLE | doi:10.20944/preprints202311.0196.v1

Molecular Identification of Fungal Species by Multiplex-qPCR in Candidal Vulvovaginitis Specimens and Antifungal Susceptibility

Inés Arrieta-Aguirre, Pilar Menéndez-Manjón, Giulia Carrano, Ander Diez, Íñigo Fernandez de Larrinoa, María-Dolores Moragues

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Vulvovaginal Candidiasis; qPCR; Candida species, antifungal susceptibility, resistance-related mutations

Online: 3 November 2023 (04:02:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202304.0834.v1

Antifungal Susceptibility of Oral Candida Isolates From Mother-Infant Dyads to Nystatin, Fluconazole, and Caspofungin.

Naemah A Alkhars, Anthony Gaca, Yan Zeng, Nisreen Al-Jallad, Elena Rustchenko, Tong Tong Wu, Eli Eliav, Jin Xiao

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Antifungal agent; in vitro susceptibility; oral Candida; nystatin; fluconazole; caspofungin

Online: 24 April 2023 (07:49:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0080.v1

The Frequency and Patterns of Post-COVID-19 Vaccination Syndrome Reveal Initially Mild and Potentially Immunocytopenic Signs in Primarily Young Saudi Women

Kamaleldin B. Said, Amal Al-Otaibi, Luluh Aljaloud, Basmah Al-Anazi, Ahmed Alsolami, Fayez Saud Alreshidi

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: COVID-19 reactions; ITP syndromes 2; COVID-vaccine women susceptibility

Online: 6 June 2022 (09:43:09 CEST)

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Vaccination is the most promising approach for ending or containing the SARS-CoV2 pandemic. However, serious post-COVID vaccine reactions including immunocytopenia (ITP) syndrome has been increasingly reported. Several factors cause increased risks including multiple doses, age-dependent heterogeneity in immune-responses, platelet cross-reactions with microbial components, and Long-COVID syndrome. Thus, in the absence of a widely available specific therapeutics, vigilance is important while more studies are imperative. Using a structured questionnaire sent to different regions in Saudi Arabia, we conducted a comprehensive investigation on the frequency, rates, disease patterns, and patient demographics of post-COVID-19 side effects on febrile patients after three major vaccines. Results indicated the majority administered Pfizer BioNtech vaccine (81%, n=809); followed by AstraZeneca (16%, n=155); and Moderna (3%, n=34). In overall 998 participants, 74% (n=737) had no serious symptoms; however, 26.2% (n=261) revealed typical syndrome. In a focused group of 722, shortness of breath (20%), bruises or bleeding (18%), inattention (18%), GIT symptoms (17.6%), skin irritation (8.6%), and anosmia and ageusia (8%) were the most prominent. The onset time was mostly in 1-3 days in 49% (n=128), followed by 4-7 days in 21.8% (n=57), 8-14 days in 16.5% (n=43), and more than a month in 12.6% (n=33). The onsets occurred mostly after the first, second, or both doses 9%, 10%, and 7%, respectively. The frequency of symptoms was significantly higher among after Moderna ® vaccine (P-value = 0.00006) and it was significantly lower in participants who received Pfizer (P-value 0.00231). We did not find significant difference in symptoms related to differences in regions. Similarly, the region, age, gender, education, and nationality had no influence in the dose and onset timings. The findings of this study have significant clinical implications in disease management strategies, preventive measures, and vaccine development. Future vertical studies would reveal more insights into the mechanisms of post-COVID vaccine syndrome.

Preprint ARTICLE | doi:10.20944/preprints202102.0045.v1

Candida Albicans ERG11 Gene Polymorphism: Impact on Its In Vivo Virulence and Susceptibility to Fluconazole According to the Galleria Mellonella Model

Marcel Patindoilba Sawadogo, Adama Zida, Issiaka Soulama, Samuel S Sermé, Thierry Kiswendsida Guiguemdé, Ibrahim Sangaré, Clément Kafando, Sanata Bamba, Rasmata Ouédraogo-Traoré, Robert Tinga Guiguemdé

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Burkina Faso; Candida albicans; ERG11; virulence; susceptibility; Fluconazole; Galleria mellonella

Online: 1 February 2021 (14:31:17 CET)

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Preprint REVIEW | doi:10.20944/preprints202012.0681.v1

Understanding Root Rot Disease in Agricultural Crops

Bruce A. Williamson-Benavides, Amit Dhingra

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Fungi; oomycetes; resistance; susceptibility; molecular mechanisms; quantitative trait loci; mapping

Online: 28 December 2020 (11:12:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202008.0089.v1

Landslide Susceptibility Mapping at Two Adjacent Catchments Using Advanced Machine Learning Algorithms

Ananta Man Singh Pradhan, Yun-Tae Kim

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: Deep Neural Network; Extreme Gradient Boosting; Random Forest; Landslide Susceptibility

Online: 4 August 2020 (11:13:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0265.v1

Identification and Differences in Antimicrobial Susceptibility of Lactococcus garvieae from Farmed Grey Mullet ( Mugil cephalus ) and Non-Grey Mullet in Southern Taiwan

Jian-Lin Lee, Shu-Yung Chiu, Che-Chun Chen, Chishih Chu, Jiann-Hsiung Wang

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Lactococcus garvieae; Grey Mullet (Mugil cephalus); Multiplex PCR; Antibiotic Susceptibility

Online: 12 July 2020 (15:41:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202002.0051.v3

Bulk and Single-Cell Transcriptomics Identify Tobacco-Use Disparity in Lung Gene Expression of ACE2, the Receptor of 2019-nCov

Guoshuai Cai

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Wuhan 2019-nCov; ACE2; expression; susceptibility; race; age; gender; smoking; single cell

Online: 2 March 2020 (01:38:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.2089.v1

Exploring the Impact of IL-33 Gene Polymorphism (rs1929992) on Susceptibility to Chronic Urticaria and its Association with Serum Interleukin-33 levels

Carmen-Teodora Dobrican-Băruța, Diana Mihaela Deleanu, Mihaela Iancu, Ioana Adriana Muntean, Irena Nedelea, Radu-Gheorghe Bălan, Lucia Maria Procopciuc, Gabriela Adriana Filip

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: chronic urticaria; genetic polymorphisms; IL-33; SNP rs1929992; cytokine; autoimmune; susceptibility

Online: 26 September 2024 (17:07:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0479.v1

Optimization of Magnetic Susceptibility Weighted Imaging for Female Pelvic Scans

Wenjie Liu, Bin Yu, Furong Lv, Kaiwen Liang, Zhibo Xiao

Subject: Public Health And Healthcare, Other Keywords: magnetic resonance imaging; magnetic susceptibility weighted imaging; flip angle; pelvic disease.

Online: 7 June 2024 (10:24:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.2009.v1

Susceptibility of Broflanilide and a Broflanilide-based Insecticide Formulation against the Common Bed Bug, Cimex lectularius L. (Hemiptera: Cimicidae)

Kai Dang, Stephen Lindsay Doggett

Subject: Biology And Life Sciences, Other Keywords: bed bug; broflanilide; susceptibility; efficacy; surface substrates; aged residues; ovicidal efficacy

Online: 30 April 2024 (17:06:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0444.v1

Landslide Susceptibility Evaluation of BO-CNN Gengma Seismic Zone Considering InSAR Deformation

Yunlong Deng, Xiaoqing Zuo, Yongfa Li, Xincheng Zhou

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: InSAR; landslide susceptibility; random forest; support vector machine; convolutional neural network

Online: 7 September 2023 (04:03:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1358.v1

Exploration and Comparison of the Effect of Conventional and Advanced Modeling Algorithms on Landslide Susceptibility Prediction: A Case Study from Yadong Country, Tibet

Zhu Liang, Weiping Peng, Wei Liu, Houzan Huang, Jiaming Huang, Kangming Lou, Guochao Liu, Kaihua Jiang

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: Landslide Susceptibility; Information Value; Logistic regression; Machine learning; Deep learning; GIS

Online: 19 May 2023 (02:28:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0464.v1

Lipoic Acid-Functionalized Hexanuclear manganese(III) Nanomagnets Suitable for Surface Grafting

Marta Orts-Arroyo, Carlos Rojas-Dotti, Nicolás Moliner, José Martínez-Lillo

Subject: Chemistry And Materials Science, Inorganic And Nuclear Chemistry Keywords: manganese; lipoic acid; salicylamidoxime; crystal structure; magnetic susceptibility; single-molecule magnet

Online: 8 May 2023 (08:14:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0385.v1

Evaluation of the Novel Culture-Based AtbFinder Test-System for the Selection of Optimal Antibiotics for Critically Ill Patients With Polymicrobial Infections Within 4 H

George Tetz, Victor Tetz

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: antibiotic resistance; antimicrobial susceptibility testing; novel diagnostics; polymicrobial; sputum; drug resistant

Online: 14 April 2021 (14:21:15 CEST)

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Preprint REVIEW | doi:10.20944/preprints202009.0654.v1

BARD1 and Breast Cancer: The Possibility of Creating Screening Tests and New Preventive and Therapeutic Pathways for Predisposed Women

Marcin Śniadecki, Michał Brzeziński, Katarzyna Darecka, Dagmara Klasa-Mazurkiewicz, Patryk Poniewierza, Marta Krzeszowiec, Natalia Kmieć, Dariusz Wydra

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: breast cancer; BARD1; surveillance; management; genetic testing; predisposition; susceptibility; neoadjuvant; chemotherapy

Online: 26 September 2020 (17:32:52 CEST)

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Preprint REVIEW | doi:10.20944/preprints202008.0371.v1

BARD1 and Breast Cancer: the Possibility of Creating Screening Tests and New Preventive and Therapeutic Pathways for Predisposed Women

Marcin Śniadecki, Michał Brzeziński, Katarzyna Darecka, Dagmara Klasa-Mazurkiewicz, Patryk Poniewierza, Marta Krzeszowiec, Natalia Kmieć, Dariusz Wydra

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: breast cancer; BARD1; surveillance; management; genetic testing; predisposition; susceptibility; neoadjuvant; chemotherapy

Online: 18 August 2020 (03:08:11 CEST)

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Preprint SHORT NOTE | doi:10.20944/preprints202004.0516.v1

Is There a Relationship Between Blood Group and COVID-19 Susceptibility?

Davide Golinelli, Erik Boetto, Maria Pia Fantini

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: ABO blood groups system; COVID-19; susceptibility; SARS-CoV-2; SARS

Online: 30 April 2020 (05:51:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202001.0385.v1

A Machine Learning based Approach for Wildfire Susceptibility Mapping. The Case Study of Liguria Region in Italy

Marj Tonini, Mirko D'Andrea, Guido Biondi, Silvia Degli Esposti, Andrea Trucchia, Paolo Fiorucci

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: wildfires; susceptibility mapping; machine learning; random forest; model validation; Liguria region

Online: 31 January 2020 (11:40:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.1918.v1

High Resolution Precipitation and Soil Moisture Data Integration for Landslide Susceptibility Mapping

Yaser Peiro, Evelina Volpe, Luca Ciabatta, Elisabetta Cattoni

Subject: Engineering, Safety, Risk, Reliability And Quality Keywords: Landslide Susceptibility Map; High-Resolution Precipitation and Soil Moisture; Machine Learning Algorithm

Online: 25 October 2024 (02:59:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1082.v1

Effect of Temperature Over the Growth and Biofilm Formation of the Thermotolerant Aspergillus flavus

José Alejandro Hernández-Benítez, Brenda Nallely Santos-Ocampo, Daniel Genaro Rosas-Ramírez, Adrian Ramírez-Granillo, Luis Antonio Bautista-Hernández, Víctor Manuel Bautista-de Lucio, Nestor Octavio Pérez, Aída Verónica Rodríguez-Tovar

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Aspergillus flavus; biofilm; thermotolerant; extracellular matrix; lipid droplets; antifungal susceptibility

Online: 13 September 2024 (11:25:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0129.v1

Development of an Environmental Vulnerability Index (EVI) Using Analytical Hierarchy Process and Application to the São Francisco River Basin, Brazil

Clívia Dias Coelho, Demetrius David da Silva, Ricardo Santos Silva Amorim, Bruno Nery Fernandes Vasconcelos, Ernani Lopes Possato, Elpídio Inácio Fernandes Filho, Pedro Christo Brandão, José Ambrósio Ferreira Neto, Lucas Vieira Silva

Subject: Environmental And Earth Sciences, Environmental Science Keywords: multicriteria analysis; GIS; land use adequacy; burned area; erosion susceptibility; water balance

Online: 2 August 2024 (10:41:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0959.v1

Magnetic Prospecting as a Tool for the Characterization of Mining Dams in the La Carolina Mining District (South of Spain)

Rosendo Mendoza, Javier Rey, Jose Vílchez, M. Carmen Hidalgo

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: Tailings dams; Environmental risk; Magnetometry; Magnetic susceptibility; La Carolina mining district; Spain

Online: 18 March 2024 (09:53:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.0978.v2

Soil Erosion and Landslide Susceptibility Mapping Using Rock Engineering System Methodology: The Case of Mandra Fatal Flash Flood (2017) in Western Attica, Greece

Nikolaos Tavoularis

Subject: Environmental And Earth Sciences, Soil Science Keywords: mandra flash flood; soil erosion; slope failure; RES; mitigation measures; landslide susceptibility

Online: 11 October 2023 (16:02:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0903.v1

Can Chitosan Applications in Pre- and Post-Harvest affect the Quality and Antioxidant Contents of Red Raspberries?

Ermes Lo Piccolo, Piera Quattrocelli, Michelangelo Becagli, Roberto Cardelli, Hafsa El Horri, Lucia Guidi, Marco Landi, Susanna Pecchia

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: anthocyanins; antioxidants; ascorbic acid; fungal decay; pre-harvest factors and susceptibility; storage

Online: 14 September 2023 (05:26:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0107.v1

Magnetic and Geochemical Properties of Zagreb City Area Soils

Stanislav Frančišković-Bilinski, Josip Peco, Sanja Sakan, Dragana Đorđević, Dejan Inđić

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: magnetic susceptibility; geochemistry; Zagreb urban area (Croatia); soils; anthropogenic influence; geological background

Online: 4 September 2023 (15:26:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0425.v1

Anomalous Ferromagnetic Phase in the Gd1-xErxB4 Series: Crystal Growth, Thermal and Magnetic Properties

Sueli H. Masunaga, V. B. Barbeta, F. Abud, M. S. Torikachvilli, R. F. Jardim

Subject: Physical Sciences, Condensed Matter Physics Keywords: tetraborides; susceptibility; specific heat; geometric magnetic frustration; antiferromagnetism; flux method; Shastry Sutherland

Online: 7 July 2023 (07:40:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0141.v1

AtbFinder Diagnostic Test System Improves Optimal Selection of Antibiotic Therapy in Persons with Cystic Fibrosis

George Tetz, kristina Kardava, Maria Vecherkovskaya, Andrea Hahn, Michael Tsifansky, Anastassios Koumbourlis, Victor Tetz

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: AtbFinder; antibiotic susceptibility testing; cystic fibrosis; Pseudomonas aeruginosa; multi-drug re-sistant

Online: 11 October 2022 (04:56:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0032.v1

Towards a Healthy Car: UVC LEDs Inside Automobile HVAC Chamber Offers Effective Complementary Disinfection to Ensure Clean Cabin Air

Richard Mariita, James H. Davis, Michelle M. Lottridge, Rajul V. Randive, Hauke Witting, Johannes Yu

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: bioaerosols; bacteriophage Phi6; vehicle; automobile; HVAC; UVC LEDs; susceptibility; SARS-CoV-2

Online: 5 October 2022 (10:50:08 CEST)

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Vehicle HVAC systems can accumulate and recirculate highly infectious respiratory diseases via aerosols. Integrating UVC to complement automobile HVAC systems can protect occupants from developing allergies, experiencing inflammatory problems, or acquiring respiratory infectious diseases by inactivating pathogenic organisms. UVC can add little to no static pressure with minimal space, unlike mercury lamps which are larger and heavier. Additionally, UVC LEDs are effective at low voltage and have no mercury or glass. While previous experiments have shown UVC LED technology can reduce bacteriophage Phi6 concentrations by 1 log in 5 minutes (selected as the average time to clean the cabin air), those studies had not positioned LED within the HVAC itself or studied the susceptibility of the surrogate at the specific wavelength. This study aimed to assess the disinfection performance of UVC LEDs in automotive HVAC systems and determine the dose-response curve for bacteriophage Phi6, a SARS-CoV-2 surrogate. To achieve this, UVC LEDs were installed in a car HVAC system. To determine inactivation efficacy, a model chamber of 3.5 m3, replicating the typical volume of a car, containing the modified automobile HVAC system was filled with bacteriophage Phi6, and the HVAC was turned on with and without the UVC LEDs being turned on. The results revealed that HVAC complemented with UVC reduced bacteriophage Phi6 levels significantly more than the HVAC alone and reduced the viral concentration in the cabin by more than 1 LRV (90% viral reduction) in less than 5 minutes. The performance after 5 minutes is expected to be significantly better against SARS-CoV-2 because of its higher sensitivity to UVC, especially at lower wavelengths (below 270 nm). HVAC alone could not achieve a 90% viral reduction of bacteriophage Phi6 in 15 minutes. Applying UVC LEDs inside an HVAC system is an effective means of quickly reducing the number of aerosolized viral particles in the chamber, by inactivating microorganisms leading to improved cabin air quality.

Preprint ARTICLE | doi:10.20944/preprints202009.0516.v1

Novel Ensemble Approach of Deep Learning Neural Network Model and Particle Swarm Optimization (PSO) Algorithm for Prediction of Gully Erosion Susceptibility

Shahab S, Saeid Janizadeh, Subodh Chandra Pal, Asish Saha, Rabin Chakrabortty, Manouchehr Shokri, Amirhosein Mosavi

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: gully erosion susceptibility; deep learning neural network; particle swarm optimization; Shiran watershed

Online: 22 September 2020 (09:48:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2398.v1

Epidemiology and Genetic Susceptibility of SARS-CoV-2 of Young Children Living in Northwestern Amazon Region Presenting Acute Gastroenteritis and Respiratory Infection

Yan Cardoso Pimenta, Flávia Freitas de Oliveira Bonfim, Carlos Eduardo da Silva Figueiredo, Bruno Loreto Aragão, Mauro França Silva, Alberto Ignácio Olivares Olivares, José Paulo Gagliardi Leite, Isabella Fernandes Delgado, Marcia Terezinha Baroni de Moraes

Subject: Biology And Life Sciences, Virology Keywords: COVID-19; SARS-CoV-2; susceptibility; histo-blood group antigen; angiotensin-converting enzyme

Online: 31 July 2024 (07:48:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1249.v1

The Personalized Inherited Signature Predisposing to Non-small Cell Lung Cancer in Non-smokers

Viola Bianca Serio, Diletta Rosati, Debora Maffeo, Angela Rina, Marco Ghisalberti, Cristiana Bellan, Ottavia Spiga, Francesca Mari, Maria Palmieri, Elisa Frullanti

Subject: Public Health And Healthcare, Other Keywords: whole-exome sequencing; lung cancer susceptibility; germline variants; next-generation sequencing; oligogenic model

Online: 16 July 2024 (10:08:28 CEST)

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Lung cancer (LC) continues to be an important public health problem being the most common form of cancer and a major cause of cancer deaths worldwide. Despite the great bulk of research to identify genetic susceptibility genes by genome-wide association studies, only few loci associated to nicotine dependence have been consistently replicated. Our previously published study in few phenotypically discordant sib-pairs identified a combination of germline truncating mutations in known cancer susceptibility genes in never smoker early-onset LC patient does not present in their healthy sib. These results firstly demonstrated the presence of an oligogenic combination of disrupted cancer predisposing genes in non-smokers patients, giving experimental support to a model of a “private genetic epidemiology”. Here, we used a combination of whole-exome and RNA sequencing coupled with a discordant sib’s model in a novel cohort of pairs of never-smokers early-onset LC patients and in their healthy sibs used as controls. We selected rare germline variants predicted as deleterious by CADD and SVM bio-informatics tools and absent in the healthy sib. Overall, we identified an average of 200 variants per patient, about 10 of which in cancer predisposing genes. In most of them, RNA sequencing data reinforced the pathogenic role of the identified variants showing: i) downregulation in LC tissue (indicating “second hit” in tumor suppressor genes); ii) upregulation in cancer tissue (likely oncogene); iii) downregulation in both normal and cancer tissue (indicating transcript instability). The combination of the two techniques demonstrates that each patient has an average of six (with a range from four to eight) private mutations with functional effect in tumor predisposing genes. The presence of a unique combination of disrupting events in the affected subjects may explain the absence of familial clustering of non-small cell lung cancer. In conclusion, these findings indicate that each patient has his/her own “predisposing signature” to cancer development and suggest the use of personalized therapeutic strategies in lung cancer.

Preprint ARTICLE | doi:10.20944/preprints202309.1003.v1

Bacterial Profile, Antibiotic Susceptibility Pattern and Associated Risk Factors of Urinary Tract Infection among Reproductive Age Females Attending the Logbaba District Hospital, Douala, Cameroon

Ngwa Fabrice Ambe, Pride Bobga Tanyi, Ekwi Damian Nsongmayi, Ebai Christabel Ashu, Sangwe Bertrand Ngwa, Ngong Judith Nyeme

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Bacterial profile; Antibiotic susceptibility; reproductive age females; risk factors; Urinary tract infection (UTI)

Online: 18 September 2023 (14:36:21 CEST)

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Background: Urinary tract infection (UTI) is one of the commonest bacterial infections among reproductive age females. Untreated UTI in reproductive age female is associated with sexual dysfunction, cystitis, pyelonephritis and Pelvic inflammatory disease. At present, the antimicrobial resistance emergency has quadrupled worldwide and poses a serious threat to the treatment of patients. Thus, this study aimed to determine bacterial profile, antibiotic susceptibility pattern and associated risk factors of urinary tract infection among reproductive age females attending the Logbaba District Hospital Methods: A hospital-based cross-sectional study was conducted from January – July, 2023. Convenient sampling was employed to recruit 259 reproductive age females. Sociodemographic and risk factors information were obtained using a well-structured questionnaire. Mid-stream urine was collected and inoculated on cystine lactose electrolyte deficient media. Isolates were identified using API 20. Antibiotic sensitivity testing was performed using modified kirby-bauer susceptibility testing technique. Multivariate logistic regression model was used to assessed risk factors. A p-value < 0.05 was considered as statistically significant. Results: The overall prevalence of UTI among reproductive age females was 82/259 (31.66%). Symptomatic and asymptomatic patients reported a prevalence of 50/121(41.32%) and 32/138 (23.19%), respectively. Ages ranging from 21-30 years (AOR: 2.53 ,95% CI 1.32 – 4.43, p=0.006) and 31 – 40 years (AOR: 0.19 , 95% CI: 0.14- 0.54; p <0.0001), student (AOR: 1.8, 95% CI: 1.21 - 2.75; p = 0.010), history of UTI (5.34, 95% CI = 1.86 - 18.15; p = 0.03), symptomatic (AOR = 2.86, 95% CI1.78 - 4.67, p <0.0001) and secondary education (AOR: 0.13, 95% CI 0.08 - 0.32; p<0.0001) were predictors to UTI. Klebsiella Pneumoniae was the most frequent species 27 (32.9%), follow by E coli 22(26.8%), Staphylococcus aureus 16 (19.5%), CONS 8 (9.8%), Proteus mirabilis 6 (7.3 %) and Pseudomonas aeruginosa 3(3.7%). Majority of the isolates were sensitive to cefotaxime (87.80%), imipenem (85.7%), vancomycin (79.27%), Ofloxacillin (76.83%), Ceftriaxone (75.61%), Ciprofloxacin (74.39%), Gentamicin (71.95%) and Doxycycline (69.51%), and resistant to Amoxicillin (51.22%), cotrimoxazole (47.56%) and Azithromycin (31.71%) , All the isolates were multidrug drug resistant (100%) and Klebsiella Pneumoniae and E coli were the most multidrug drug resistant species Conclusion: In the present study, the prevalence of urinary tract infection among reproductive age females was high and considerably a high proportion of multidrug resistance was observed. This result will have a significant impact on the selection of appropriate antimicrobial agents for the treatment of urinary tract infection in the study area.

Preprint ARTICLE | doi:10.20944/preprints202305.1226.v1

Geological Hazard Susceptibility Evaluation using Information Quantity, Deterministic Coefficient, and Logistic Regression Models and Their Comparison at Xuanwei, China

Shaohan Zhang, Shucheng Tan, Lifeng Liu, Duanyu Ding, Yongqi Sun, Jun Li

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: information model; certainty factor model; logistic regression model; geological hazard; susceptibility; Xuanwei city

Online: 17 May 2023 (10:20:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202202.0005.v2

Analysis Of Ac Magnetic Susceptibility Data Of A Room Temperature Superconductor

Jorge E. Hirsch

Subject: Physical Sciences, Condensed Matter Physics Keywords: hydride superconductor; room temperature superconductor; pressure; ac magnetic susceptibility; raw data; background signal

Online: 4 February 2022 (10:31:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202201.0370.v1

Determination of Location-Specific Solidification Cracking Susceptibility for a Mixed Dissimilar Alloy Processed by Wire-Arc Additive Manufacturing

Soumya Sridar, Noah Sargent, Xin Wang, Michael A. Klecka, Wei Xiong

Subject: Chemistry And Materials Science, Metals, Alloys And Metallurgy Keywords: functionally graded alloy; directed energy deposition; solidification cracking susceptibility; ICME; CALPHAD; high entropy.

Online: 25 January 2022 (08:52:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202012.0746.v1

Key Indicators to Build Country Resilience

Arnoldo Jose de Hoyos Guevara, Valeria Regina Bertoncelo

Subject: Business, Economics And Management, Accounting And Taxation Keywords: Resilience; Social Progress; Enviromental Performance; Sustainable Development Goals; Governance; World Risks; Vulnerability; Susceptibility

Online: 30 December 2020 (08:58:20 CET)

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Working Paper BRIEF REPORT

Is H34 of ACE2 an indicator of the susceptibility to SARS-CoV-2? Clues from multi-species sequence analyses

Jianghai Lin, Fengjuan Lyu, Wenjuan Xiao, Yuan Xu, Zehuan Liu

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: SARS-CoV-2; COVID-19; Angiotensin-converting enzyme 2; susceptibility; livestock; aquatic mammals

Online: 7 June 2020 (08:18:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1855.v1

Antimicrobial Susceptibility of Uropathogenic Escherichia coli with Analysis of Impact of Socio-Economic Factors in Low, Medium and High-Income Countries

Meher Rizvi, Maria Khan, Amina AL Jardani, Ujjala Ghoshal, Zaaima AL Jabri, Mohammad Ahanjan, Azza AL Mamari, Nawal AL Shizawi, Hiba Sami, Abdullah Balkhair, Adila Shaukat, Alwarith Nasser Salem Alkharusi, Abdulrahman Almahrouqi, Afreenish Hassan, Ajay Kumar, Amal Malehi, Amina Gul, Ashima Singh, Asma Said Hamed AL Shidhani, Areena Hoda Siddiqui, Aruna Poojary, Azza AL Rashdi, Bradley Langford, Dmytro Stepanskyi, Abbas Dolatabadi, Aisha Al Mufraji AL Mufraji, Elham Said Ahmed AL Risi, Garima Kapoor, Isabella Princess, Hatim Ali Eltahir, Hilal Al Sidairi, Kaitlyn Dougherty, Katia Iskandar, Ken Masters, Ibrahim Khalaf Hamdan AL Busaidi, Laila AL Yazidi, Mahfuza Nasrin, Mahmood Salim AL Subhi, Mallika Sengupta Mallika Sengupta, Manisha Khandait, Nada Khalfan AL Tamtami, Nada Khafan Alsiyabi, Nawal AL Kindi, Nazla Musthafa Luthfee, Neha Shreshtha, Nihal Mohamed Amur AL Riyami, Noora Hilal Ali AL Busaidi, Nupur Goel, Oksana Ishchenko, Omnia Mohamed Elnabawy Ahmed Taher, Pragnya Paramita Jena, Rajni Ekadashi, Razan Zadjali, Reba Kanungo, Sara Abolghasemi, Salima Al-maqbali, Sanjay Jaju, Sayantan Banerjee, Shadma Yaqoob, Shahnaz Sali, Shafqat Husnain Khan, Shalini Malhotra, Stephen Hughes, Sundas Shaukat, Syed Mohammed Atif, Vrushali Vishwas Patwardhan, Victorien Dougnon, Wahid Khan, Walid Wali, Zakariya AL Muharrmi, Zeeshana Basit, Jasashree Choudhury, Rachita Pravalina, Sanjeev Singh, Sarman Singh, Neelam Taneja, Raman Sardana, Pawan Kapoor, Rajeev Soman, Rashid Al Abri

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: community acquired UTI; Escherichia coli; antimicrobial susceptibility; Indian subcontinent; MENA; GDP; temperature

Online: 24 September 2024 (12:32:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0788.v1

Physical Vulnerability and Landslide Risk Assessment in Tegucigalpa City, Honduras

Ginés Suárez, María José Domínguez-Cuesta

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: Numerical methods and its applications; reliability and risk analysis; landslide susceptibility modeling and mapping

Online: 12 August 2024 (12:30:13 CEST)

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Preprint REVIEW | doi:10.20944/preprints202402.1101.v1

How Does Airway Surface Liquid Composition Vary in Different Pulmonary Diseases, and How Can We Use This Knowledge to Model Microbial Infections?

Dean Walsh, Jennifer Bevan, Freya Harrison

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: respiratory infection; airway surface liquid; infection models; antimicrobial susceptibility testing; ventilator-associated pneumonia; COPD

Online: 20 February 2024 (06:32:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.1331.v1

Calculation of Thermodynamic Quantities of 1D Ising Model with Mixed Spin-(s,(2t-1)/2) by Means of Transfer Matrix

Hasan Akin

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: one-dimensional Ising model with mixed spin; free energy; entropy; magnetization; susceptibility; phase transition

Online: 18 August 2023 (07:29:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0529.v1

Assessing the Dimensionality Reduction of the Geospatial Dataset Using Principal Component Analysis (PCA) and Its Impact on the Accuracy and Performance of Ensembled and Non-ensembled Algorithms

Farkhanda Abbas, Feng Zhang, Javed Iqbal, Fazila Abbas, Abdulwahed Fahad Alrefaei, Mohammed Albeshr

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: machine learning; accuracy; complexity; entropy; landslide susceptibility mapping; dimensionality reduction; Principal Component Analysis (PCA)

Online: 10 July 2023 (11:11:27 CEST)

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In this study, our primary objective was to analyze the tradeoff between accuracy and complexity in machine learning models, with a specific focus on the impact of reducing complexity and entropy on the production of landslide susceptibility maps. We aimed to investigate how simplifying the model and reducing entropy can affect the capture of complex patterns in the susceptibility maps. To achieve this, we conducted a comprehensive evaluation of various machine-learning algorithms for classification tasks. We compared the performance of these algorithms in terms of accuracy and complexity, considering both "before" and "after" scenarios of dimensionality reduction using Principal Component Analysis (PCA). Our findings revealed that reducing complexity and lowering entropy can lead to an increase in model accuracy. However, we also observed that this reduction in complexity comes at the cost of losing important complex patterns in the produced landslide susceptibility maps. By simplifying the model and reducing entropy, certain intricate relationships and uncertain patterns may be overlooked, resulting in a loss of information and potentially compromising the accuracy of the susceptibility maps. The analysis encompassed a diverse range of machine learning algorithms, including Random Forest (RF), Extra Trees (EXT), XGboost, LightGBM, Catboost, Naive Bayes (NB), K-Nearest Neighbors (KNN), Gradient Boosting Machine (GBM), and Decision Trees (DT). Each algorithm was evaluated for its strengths and limitations, considering the tradeoff between accuracy and complexity. Before dimensionality reduction, the algorithms demonstrated promising results, with RF exhibiting excellent AUC/ROC scores and average accuracy. However, computational costs were noted as a potential drawback for RF, especially when dealing with large datasets. EXT showcased robust performance and good accuracy, while XGboost demonstrated its ability to handle complex relationships within large datasets, albeit requiring careful hyperparameter tuning. The efficiency and scalability of LightGBM made it a suitable choice for large datasets, although it displayed sensitivity to class imbalance. Catboost excelled in handling categorical features, but longer training times were observed for larger datasets. NB showcased simplicity and computational efficiency but assumed independence among features. KNN, known for its capability to capture local patterns and spatial relationships, was found to be sensitive to the choice of distance metric. GBM, while capturing complex relationships effectively, was prone to overfitting without proper regularization. DT, with its interpretability and ease of understanding, faced limitations in terms of overfitting and limited generalization. After dimensionality reduction, certain algorithms exhibited improvements in their AUC/ROC scores and average accuracy, including RF, EXT, XGboost, and LightGBM. However, for a few algorithms, such as NB and DT, a decrease in performance was observed. This study provides valuable insights into the performance characteristics, strengths, and limitations of various machine learning algorithms in classification tasks. Researchers and practitioners can utilize these findings to make informed decisions when selecting algorithms for their specific datasets and requirements. We also aim to identify the potential factors contributing to the high accuracy rates obtained from these ensembled algorithms and explore possible shortcomings of non-ensembled algorithms that may result in lower accuracy rates. By conducting a comprehensive analysis of these algorithms, we seek to provide valuable insights into the benefits and limitations of ensembled approaches for landslide susceptibility mapping. Our study sheds light on the challenges faced when balancing accuracy and complexity in machine learning models for landslide susceptibility mapping. It emphasizes the importance of carefully considering the level of complexity and entropy reduction in relation to the specific patterns and uncertainties present in the data. By providing insights into this tradeoff, our research aims to assist researchers and practitioners in making informed decisions regarding model complexity and entropy reduction, ultimately improving the quality and interpretability of landslide susceptibility maps.

Preprint ARTICLE | doi:10.20944/preprints202306.0753.v1

Study on Factors Influencing Moisture Susceptibility of Warm Mix Asphalt Using the Surface Free Energy Approach

Liping Liu, Lingxiao Liu, Ying Yu

Subject: Engineering, Civil Engineering Keywords: Warm Mix Asphalt; Moisture Susceptibility; Surface Free Energy; Three-phase Model; Effective Adhesion Work

Online: 12 June 2023 (04:41:45 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202305.1236.v1

Novel Antifungals and Aspergillus Section Terrei with Potpourri Susceptibility Profiles to Conventional Antifungals

Roya Vahedi-Shahandashti, Jos Houbraken, Mike Birch, Cornelia Lass-Flörl

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: new antifungals; Aspergillus terreus; aspergillosis; antifungal susceptibility test; EUCAST; Ibrexafungerp; Manogepix; Olorofim; Rezafungin; Resistance

Online: 17 May 2023 (10:42:05 CEST)

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Preprint REVIEW | doi:10.20944/preprints202109.0441.v1

Genomic Risk Factors for Cervical Cancer

Dhanya Ramachandran, Thilo Dörk

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Cervical cancer; cervical dysplasia, HPV, HLA, GWAS, genetic susceptibility, meta-analysis, SNP, eQTL, Papillomavirus

Online: 24 September 2021 (15:28:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202410.1390.v1

Retrospective Evaluation of the Prevalence and Drug Susceptibility of Candida Species and an Analysis of Risk Factors for Oral Candidiasis

Marcin Tkaczyk, Anna Kuśka-Kiełbratowska, Wojciech Niemczyk, Dariusz Skaba, Rafał Wiench

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: Candida albicans; non-albicans Candida; denture stomatitis; drug resistance; antifungal susceptibility; species distribution; fungal prevalence

Online: 17 October 2024 (13:00:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1367.v1

Hand Carriage of Yeast in Student of Medicine, Nurses and Medical Laboratory Scientist. Impact of Infection Control Measures

Victor Silva, Ceidy Silva, Coral Silva, Rodrigo Gacitúa, Hernan Salas, Claudio Alburquenque, Viviana Silva-Abello

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Hand yeast carriage; healthcare students; C. parapsilosis; control infection; antifungal susceptibility

Online: 20 August 2024 (03:39:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1726.v1

Spin Frustrated Pyrazolato Triangular CuII Complex. Structure and Magnetic Properties, an Overview.

Walter Cañón-Mancisidor, Patricio Hermosilla-Ibáñez, Evgenia Spodine, Verónica Paredes-García, Carlos J. Gómez-García, Diego Venegas-Yazigi

Subject: Chemistry And Materials Science, Electronic, Optical And Magnetic Materials Keywords: Cu3-3OH complex; pyrazolato ligands; trinuclear complex; Spin Frustration; magnetic susceptibility; antisymmetric exchange; DFT calculations.

Online: 25 May 2023 (03:37:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0337.v2

Stacking Ensemble of Machine Learning Methods for Landslide Susceptibility Mapping in Zhangjiajie City, Hunan Province, China

Yuke Huan, Lei Song, Umair Khan, Baoyi Zhang

Subject: Environmental And Earth Sciences, Other Keywords: landslide susceptibility; stacking ensemble; machine learning; random forest; gradient boosting decision tree; extreme gradient boosting

Online: 5 October 2022 (10:29:51 CEST)

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The current study aims to apply and compare the performance of six machine learning algorithms, including three basic classifiers: random forest (RF), gradient boosting decision tree (GBDT), and extreme gradient boosting (XGB), as well as their hybrid classifiers, using the logistic regression (LR) method (RF+LR, GBDT+LR, and XGB+LR), in order to map the landslide susceptibility of Zhangjiajie City, Hunan Province, China. First, a landslide inventory map was created with 206 historical landslide points and 412 non-landslide points, which was randomly divided into two datasets for model training (80%) and model testing (20%). Second, 15 landslide conditioning factors (i.e., altitude, slope, aspect, plane curvature, profile curvature, relief, roughness, rainfall, topographic wetness index (TWI), normalized difference vegetative index (NDVI), distance to roads, distance to rivers, land use/land cover (LULC), soil texture, and lithology) were initially selected to establish a landslide factor database. Thereafter, the multicollinearity test and information gain ratio (IGR) technique were applied to rank the importance of the factors. Subsequently, we used a series of metrics (e.g., accuracy, precision, recall, f-measure, area under the ROC (receiver operating characteristic) curve (AUC), kappa index, mean absolute error (MAE), and root mean square error (RMSE)) to evaluate the accuracy and performance of the six models. Based on the AUC values derived from the models, the GBDT+LR model with the highest AUC value (0.8168) was identified as the most efficient model for mapping landslide susceptibility, followed by the XGB+LR, XGB, RF+LR, GBDT, and RF models, which achieved AUC values of 0.8124, 0.8118, 0.8060, 0.7927, and 0.7883, respectively. The results from this study suggest that the stacking ensemble machine learning method is promising for use in landslide susceptibility mapping in the Zhangjiajie area and is capable of targeting the areas prone to landslides.

Preprint ARTICLE | doi:10.20944/preprints202201.0003.v1

Superconductivity in Carbonaceous Sulfur Hydride: Further Analysis of Relation between Published AC Magnetic Susceptibility Data and Measured Raw Data

Jorge Hirsch

Subject: Physical Sciences, Condensed Matter Physics Keywords: hydride superconductor; room temperature superconductor; pressure; ac magnetic susceptibility; raw data; background signal; fine structure

Online: 4 January 2022 (12:26:48 CET)

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Working Paper ARTICLE

Theory; A Connection between Newton’s Law and Coulomb’s Law?

Christopher Pilot

Subject: Physical Sciences, Acoustics Keywords: Winterberg Model, Extended Gravity Model, Gravitational Susceptibility Model, Cosmic Vacuum Model, Dark Energy, Dark Matter

Online: 16 February 2021 (13:40:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0258.v2

Asians Do Not Exhibit Elevated Expression or Unique Genetic Polymorphisms for ACE2, the Cell-Entry Receptor of SARS-CoV-2

Ying Chen, Kejia Shan, Wenfeng Qian

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: SARS-CoV-2; cell-entry receptor; ACE2; The Cancer Genome Atlas; susceptibility; demographic factors; polymorphism

Online: 25 February 2020 (06:30:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints201712.0124.v1

Single Crystal Growth and Superconducting Properties of Antimony Substituted NdO_0.7F_0.3BiS₂

Satoshi Demura, Satoshi Otsuki, Yuita Fujisawa, Hideaki Sakata

Subject: Chemistry And Materials Science, Electronic, Optical And Magnetic Materials Keywords: BiS2-based superconductor; Flux growth; Layered structure; Superconducting Properties; Magnetic susceptibility measurement; Electrical resistivity measurement

Online: 18 December 2017 (13:38:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.2063.v1

Multi-Echo Complex Quantitative Susceptibility Mapping and Quantitative Blood Oxygen Level Dependent Magnitude (mcQSM+qBOLD or mcQQ) for Oxygen Extraction Fraction (OEF) Mapping

Junghun Cho, Jinwei Zhang, Pascal Spincemaille, Hang Zhang, Thanh D. Nguyen, Shun Zhang, Ajay Gupta, Yi Wang

Subject: Engineering, Bioengineering Keywords: oxygen extraction faction; quantitative susceptibility mapping; quantitative blood oxygen level-dependent imaging; multi-echo complex quantitative susceptibility mapping and quantitative blood oxygen level dependent magnitude; QSM+qBOLD; QQ; mcQQ; deep learning; magnetic resonance imaging; MRI

Online: 27 December 2023 (09:10:19 CET)

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Preprint ESSAY | doi:10.20944/preprints202408.1624.v2

Homeostasis - Resiliance and Susceptibility

Steven Olsen

Subject: Public Health And Healthcare, Primary Health Care Keywords: Disease causation; Homeostasis profile; Set point reference images; Resilience; Susceptibility; Stress/Reaction Dynamics; Epigenetics

Online: 22 September 2024 (06:40:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.2024.v1

Development and Optimization of a Novel Passive Shim System for Human Orbitofrontal Cortex Imaging at 4T MRI

Mohan L. Jayatilake, Sahan M. Vijithananda, Jing-Huei Lee

Subject: Engineering, Bioengineering Keywords: MRI; 4T MRI; Brain; Orbito-frontal Cortex Imaging; Magnetic Susceptibility; Passive Shim Development; Passive Shim Placement.

Online: 29 January 2024 (15:43:28 CET)

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