Working Paper Brief Report Version 1 This version is not peer-reviewed

Is H34 of ACE2 an indicator of the susceptibility to SARS-CoV-2? Clues from multi-species sequence analyses

Version 1 : Received: 5 June 2020 / Approved: 7 June 2020 / Online: 7 June 2020 (08:18:54 CEST)

How to cite: Lin, J.; Lyu, F.; Xiao, W.; Xu, Y.; Liu, Z. Is H34 of ACE2 an indicator of the susceptibility to SARS-CoV-2? Clues from multi-species sequence analyses. Preprints 2020, 2020060067 Lin, J.; Lyu, F.; Xiao, W.; Xu, Y.; Liu, Z. Is H34 of ACE2 an indicator of the susceptibility to SARS-CoV-2? Clues from multi-species sequence analyses. Preprints 2020, 2020060067

Abstract

SARS-CoV-2, the causal agent of the globally spreading COVID-19, is capable of infecting variable animals besides human being. We evaluated the potential susceptibility of important livestock, pets and aquatic mammals by performing a multi-species sequence analysis of ACE2 based on the reported affected and unaffected animals. We identified a triple amino acid pattern of ACE2, at position 30, 31 and 34, that might be associated with SARS-CoV-2 infection and H34 might be an indicator of the susceptibility to COVID-19.

Subject Areas

SARS-CoV-2; COVID-19; Angiotensin-converting enzyme 2; susceptibility; livestock; aquatic mammals

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.