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Preprint ARTICLE | doi:10.20944/preprints202309.0383.v1

Payment Behavioral Response Mechanisms for All-Age Retrofitting of Older Communities: A Study Among Chinese Residents

Yang Zhang, Lei Dong

Subject: Social Sciences, Behavior Sciences Keywords: older community renovation; all-age retrofitting; anxiety; PLS-SEM; payment behavioral response mechanisms

Online: 6 September 2023 (09:25:15 CEST)

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Preprint REVIEW | doi:10.20944/preprints201706.0101.v1

High Speed All-Optical Logic Gate Using QD-SOA and its Application

Shuai Zhao, Hongyu Hu

Subject: Physical Sciences, Optics And Photonics Keywords: QD-SOA; all-optical logic gates; PRBS; all-optical latches; all-optical encryption

Online: 21 June 2017 (11:29:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0911.v1

Age Profiles for SARS-CoV-2 Variants in England and Wales and States of the USA (2020 to 2022): Impact on All-Cause Mor-Tality

Rodney P Jones, Andrey Ponomarenko

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: COVID–19; all-cause mortality; single year of age; gender; complex system; pathogen interference; seasonality; small RNAs

Online: 12 May 2023 (09:01:29 CEST)

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Since 2020 COVID-19 has caused serious mortality around the world. Given the ambiguity in es-tablishing COVID-19 as the direct cause of death we first investigate the effects of age and sex upon all-cause mortality during 2020 and 2021 in England and Wales. Since infectious agents have their own unique age profile for death, we explore several methods to adjust single year of age deaths in England and Wales during 2019 (the pre-COVID-19 base year) to a pathogen-neutral single year of age baseline. This adjusted base year is then used to confirm the widely reported higher deaths in males for most ages above 43 years in both 2020 and 2021. During 2020 (+ COVID-19 but no vac-cination) both male and female population-adjusted deaths were significantly increased above age 35. A significant reduction in all-cause mortality among both males and females aged 75+ could be demonstrated in 2021 during widespread COVID–19 vaccination, however, below age 75 deaths progressively increased. This finding arises from a mix of vaccination and year of age profiles of deaths for the different SARS-CoV-2 variants. In addition, specific effects for age around puberty were demonstrated where females had higher deaths rather than males. There is evidence that year-of-birth cohorts may also be involved, indicating that immune priming to specific pathogen outbreaks in the past may lead to lower deaths for some birth cohorts. To specifically identify the age profile for the COVID-19 variants in 2020 to 2023, we employ the proportion of total deaths at each age which are potentially due to or ‘with’ COVID-19. The original Wuhan strain, and the Alpha variant show somewhat limited divergence in the age profile with the Alpha variant shifted to a moderately higher proportion of deaths below age 84. The Delta variant specifically targeted persons below age 65. The Omicron variants showed significantly lower proportion of overall mortality, with markedly higher relative proportion of deaths above age 65 steeply increasing with age to a maximum around 100 years of age. A similar age profile for the variants can be seen in the age-banded deaths in US states – although slightly obscured by using age bands rather than single year of age. However, the US data shows that higher male deaths are greatly dependent on age and the COVID-variant. Deaths determined as ‘due to’ COVID-19 (as opposed to ‘involving’ COVID-19) in England and Wales were especially over-estimated in 2021 relative to the change in all-cause mortality. This arose as a by-product of an increase in COVID-19 testing capacity in late 2020. Potential structure-function mechanisms for the year of age specificity of SARS-CoV-2 var-iants are discussed. The question is posed as to whether vaccines based on different variants carry the specific age profile through into the vaccine.

Preprint ARTICLE | doi:10.20944/preprints202304.0248.v1

Effect of Age, Sex, and COVID-19 Vaccination History on All-Cause Mortality: Unexpected Outcomes in a Complex Biological and Social System

Rodney P Jones, Andrey Ponomarenko

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: COVID–19; vaccination; all-cause mortality; age; gender; complex system; pathogen interference; seasonality; miRNAs; nonspecific vaccine effects

Online: 12 April 2023 (07:06:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0333.v1

The nonspecific effects of COVID-19 vaccination upon non-COVID-19 all-cause mortality (NCACM) in the population of England: Effects of age, sex, COVID-19 variant, vaccination history, and time in a real-world study from Jan-21 to May-23

Rodney P Jones, Andrey Ponomarenko

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: COVID–19; vaccination; all-cause mortality; age; gender; complex system; pathogen interference; seasonality; miRNAs; negative vaccine effectiveness; nonspecific vaccine effects

Online: 4 January 2024 (07:32:40 CET)

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All vaccines exhibit specific and nonspecific effects. Specific effects are shown by the efficacy against the target pathogen, while nonspecific effects can be detected by the change in all-cause mortality. The real-world non-COVID-19 all-cause mortality (NCACM) data for the population of England between January 2021 and May 2023 was assessed. All vaccines administered were based on the original Wuhan antigen. Each gender and age group, along with COVID-19 variant shows its own unique NCACM vaccination benefit/disbenefit time profile. The efficacy of COVID-19 vaccination against COVID-19 disease/death per se is undisputed, however, the nonspecific outcomes of COVID–19 vaccination is far more nuanced than have been widely appreciated. This confirms an earlier study on the unanticipated nonspecific effects of influenza vaccination against all-cause winter mortality. Interestingly, a high proportion of NCACM beneficial effects occurred during the first 21 days following COVID-19 vaccination, while the worst example of increased NCACM occurred during the fourth dose of COVID-19 vaccination in 19–40-year-olds for the interval >21 days post vaccination which led to NCACM 3- to 10-times higher than in the unvaccinated. By the time of the Omicron variant, NCACM outcomes in those aged 90+ are mostly adverse. The beneficial nonspecific effects of COVID-19 vaccination increase with age and reach their maximum effect during the second week post vaccination for age groups below 50 years, rising to during the third week for those aged 70+. Finally, we discuss the mechanisms by which COVID-19 vaccination could induce wider nonspecific effects. Most of these mechanisms seem to depend on gene regulation by noncoding RNAs which also interact with mRNAs. We suggest that further international studies are required to discern the nonspecific NCACM effects of the different COVID-19 variants other than the three variants prevalent in the UK, and different types/manufacturer of COVID-19 vaccines which have been employed around the world. We can only speculate regarding the nonspecific effects of the COVID-19 vaccines administered to persons with an asymptomatic infection, and during vaccine waning. Vaccines not only need to be effective against the target pathogen, as primarily determined by antibody production, but need to minimize any unanticipated adverse nonspecific effects against all-cause mortality.

Preprint ARTICLE | doi:10.20944/preprints202205.0108.v1

The Impact of Cardiac Comorbidity Sequence at Baseline and Mortality Risk in Type 2 Diabetes Mellitus: A Retrospective Population-Based Cohort Study

Sharen Lee, Teddy Tai Loy Lee, Oscar Hou In Chou, Keith Sai Kit Leung, Abraham Ka Chung Wai, Wing Tak Wong, Tong Liu, Carlin Chang, Gary Tse

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: comorbidity; sequence; all-cause mortality; medication

Online: 9 May 2022 (07:36:42 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1245.v1

A Comparative Review of Models for All-Solid-State Li-Ion Batteries

Erkin Yildiz, Mattia Serpelloni, Alberto Salvadori, Luigi Cabras

Subject: Engineering, Mechanical Engineering Keywords: All-solid-state batteries; Modeling; Multiscale compatibility

Online: 20 March 2024 (15:37:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.1696.v1

Age and Generalized Trust in the United States: What Do WVS Data Say?

Ya'akov M, Bayer

Subject: Social Sciences, Decision Sciences Keywords: trust; age

Online: 26 September 2023 (05:15:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202303.0065.v1

A Fundamental Study of Composite Numbers as a Different Perspective on Problems Related to Prime Numbers

Ahmet Furkan Gocgen, Ejder Aysun

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: prime numbers; composite numbers; prime-composite relationship; formula of composite; formula of all composite; formula of all odd composite

Online: 3 March 2023 (09:13:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.0273.v1

Carotid Plaques and Hypertension on the Risk of Cardiovascular Disease and All-Cause Mortality

Vilma Dzenkeviciute, Tadas Adomavicius, Gabriele Tarulyte, Egidija Rinkuniene, Vytautas Kasiulevicius, Jolita Badariene

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: all-cause mortality; cardiovascular disease; carotid plaque; hypertension

Online: 5 April 2024 (03:57:02 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1126.v1

Different Levels of Therapeutic Strategies to Recover the Microbiome to Prevent/Delay Acute Lymphoblastic Leukemia (ALL) or Arrest Its Progression in Children

Tommaso Silvano Aronica, Miriam Carella, Carmela Rita Balistreri

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Acute lymphoblastic leukemia (ALL); microbiome; GM; therapeutic strategies

Online: 21 March 2024 (04:25:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.0674.v2

Excess Mortality and the Effect of the COVID-19 Vaccines Part 1: European Data

Peter Hegarty

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: COVID-19; vaccination; all-cause mortality; excess mortality

Online: 15 September 2023 (05:26:17 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202102.0367.v2

An Emergency Management Doctrine

David Redman

Subject: Business, Economics And Management, Accounting And Taxation Keywords: All-Hazard; Emergency Management; Mitigation; Preparedness; Recovery; Response

Online: 13 July 2021 (10:07:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201811.0182.v1

Effect of PWHT Temperature and Time on Hardness and Microstructure of 410NiMo Weld Metal

Uğur Özdemir, Selçuk Keskinkılıç, Filiz K. Acar, Fikret Kabakci, Mustafa Acarer

Subject: Chemistry And Materials Science, Metals, Alloys And Metallurgy Keywords: 410NiMo, all weld metal, heat treatment, hardness, microstructure

Online: 7 November 2018 (16:24:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints201808.0414.v1

Highly-efficient longitudinal second-harmonic generation from doubly-resonant AlGaAs nanoantennas

Lei Xu, Mohsen Rahmani, Daria Smirnova, Khosro Zangeneh Kamali, Guoquan Zhang, Dragomir Neshev, Andrey Miroshnichenko

Subject: Physical Sciences, Optics And Photonics Keywords: Second harmonic generation, Mie resonances, all-dielectric nanoparticles

Online: 23 August 2018 (11:31:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1340.v1

Cs2AgBiBr6 and Cs2TiBr6 Perovskite Solar Cells: The Challenges and Research Roadmap for Power Conversion Efficiency Improvement

Taame Abraha Berhe, Etsana Kiros Ashebir, Berhe Tadese Abay

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: lead free; all inorganic; halide double perovskite; performance improvement

Online: 22 March 2024 (11:25:39 CET)

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The stability issues in the widely known organic inorganic halide perovskite, CH3NH3PbI3, lead to the development of alternative halide double perovskite materials which get great attention in recent times. Although the stability issue seems promising, both materials and device performance of these photovoltaic materials remain inferior and challenging for improvements. Furthermore, the power conversion efficiency of single junction organic inorganic halide perovskite is now 24.2% and 29.15% for textured monolithic perovskite/silicon tandem solar cell, but for all-inorganic halide perovskite solar cell is 7.11% and halide double perovskite solar cells based on Cs2AgBiBr6 and Cs2TiBr6 is 2.8% and 3.3%, respectively, which is far less than 24.2% and 29.15%, respectively. This creates big question and concern that can both all-inorganic halide perovskite solar cell and halide double perovskites solar cells really be an acceptable alternatives to replace organic inorganic halide perovskite solar cells or lead based perovskite solar cells in the market in order to realize the practical applications? Not only this concern, but also there are many other big challenges facing by halide double perovskite solar cells. Such big challenges include: a) geometric constraints and limited integration with interfacial materials, b) dynamic disorder and a wide bandgap and localized conduction band caused by cubic unit cell which restrains the interactions of orbitals, c) high processing temperature which may limit on the diverse applications, d) low electronic dimensionality making them less appropriate for single junction solar cell purpose and etc. Moreover, origin of electronic and optical properties such as the polarizability, the presence of molecular dipoles and their influence on the dynamics of the photo-excitations in the halide double perovskites remains unlock concern that need to be elucidated. Now, another big question is how to develop overcoming mechanisms for such challenges. Can we really overcome these current limitations faced by halide double perovskites so that we use them for commercialization? This research roadmap for performance improvement is suggested focusing on: materials surface and bulk engineering, bandgap engineering, interfacial engineering, composition engineering, doping engineering, device architectural engineering, polar and domain order engineering. This was the reason that this review was developed in order to forward great contributions to the readers and commercial ventures.

Preprint REVIEW | doi:10.20944/preprints202401.1974.v1

Transforming Growth Factor Beta and Alveolar Rhabdomyosarcoma: A Challenge of Tumor Differentiation and Chemotherapy Response

Bhavya Bhushan, Rosa Iranpour, Amirmohammad Eshtiaghi, Simone Cristina Da Silva Rosa, Benjamin W Lindsey, Joseph W. Gordon, Saeid Ghavami

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Rhabdomyosarcoma; Combination-therapy; all trans retinoic acid; TGF-beta1

Online: 29 January 2024 (04:46:48 CET)

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Preprint REVIEW | doi:10.20944/preprints202307.1074.v1

The Anterolateral Ligament of the Knee in Paediatric Patients: What Do We Know? A Systematic Review

Ludovico Lucenti, Gianluca Testa, Marco Montemagno, Marco Sapienza, Arcangelo Russo, Fabrizio Di Maria, Claudia De Cristo, Vito Pavone

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: knee; anterolateral ligament; all; ligament injury; paediatrics; anterolateral capsule

Online: 17 July 2023 (08:13:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202202.0247.v2

Approach for CO2 Emission Related Cost Functions in the Context of Trade-Off Investigations of a Future Energy Efficient European Aviation

Peter Förster, Bekir Yildiz, Thomas Feuerle, Peter Hecker

Subject: Engineering, Control And Systems Engineering Keywords: cost estimation; all-electric aircraft; European air traffic network

Online: 17 March 2022 (09:04:29 CET)

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Aircraft emissions represent a relevant amount of human induced CO2. Globally, up to 2.5 per cent of such emissions stem from the aviation industry. In order to investigate the effects within the atmosphere, realistic flight profiles are necessary to provide quantitatively tangible values of emissions. The flight profiles and the according fuel consumption can be calculated by using waypoints from flight plans and Base of Aircraft Data (BADA). This paper presents an approach to refine the fuel consumption by integrating the passenger load into the calculation. Since effects of emissions have to be assessed on a greater scale, such as on the European air traffic network, the presented approach provides cost functions for CO2 emissions for different aircraft types and load factors. The cost functions were derived by means of regression analyses of BADA based calculated flight profiles with a step size of one second. The calculations are based on real historic traffic scenarios of several days. The derived aircraft specific fuel burn coefficients enable a simple and efficient integration of CO2 estimations depending on the flight distance, load factor and aircraft type. This can be applied to large traffic scenarios to also study different set-ups such as travel restrictions, other disruptions or an alteration in the traffic system as a whole. In order to enable the assessment of further aspects of such changes to the European air traffic system at large and to foster reproducibility and comparability of related studies, we provide further general-purpose cost estimation functions for several important key characteristics. Besides fuel consumption, we develop cost estimations for air navigation fees and maintenance for conventional aircraft. Those functions are also provided for the design concept of a short-range all-electric aircraft. This propeller aircraft features game-changing technologies such as active laminar flow control, active load alleviation and advanced materials and structure concepts. The approaches discussed in this paper will focus on the generic aspects of aircraft related costs, which can be derived from general available data. For the sake of reproducibility, the results will be made publicly available.

Preprint ARTICLE | doi:10.20944/preprints202310.1387.v2

Uncovering the Blueprint of Aging: How Aging Causes Late-Life Disease

Carina Kern, Justin Stebbing

Subject: Biology And Life Sciences, Aging Keywords: ageing; age-related disease; antagonistic pleiotropy; biological constraint; hyperfunction; hypofunction; programmatic ageing; trade-off ;

Online: 23 November 2023 (04:05:44 CET)

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The evolutionary theory of aging, particularly antagonistic pleiotropy (AP), provides an account of the ultimate origins of aging. What remains unclear is the nature of the proximate mechanisms by which AP gives rise to diseases of aging, like cardiovascular disease and Alzheimer’s disease. Damage-centric theories focusing on loss of genetic and cellular function have been proposed, as well as programmatic theories focusing on unwanted gene and cellular function. The latter include the hyperfunction and developmental theory that view aging as the futile continuation, or run-on, of growth and developmental programmes into later life. Yet neither type of theory has performed well in explaining late-life disease aetiology, particularly with respect to disease onset, presentation and progression. What is proposed here in this review is a new programmatic theory of aging. We argue that the emergence of many specific diseases may involve quasi-programmes that are not the result of run-on, but rather are triggered by other factors in late life. Such triggers may be non-programmatic (e.g. infection, mechanical injury) or programmatic. Moreover, the consequent pre-pathological and pathological changes may in some cases trigger further changes, leading to futile and destructive cascades of quasi-programmes and pathology. The origins of triggered quasi-programmes can be traced to biological constraint i.e. the inability of organisms to optimise all functions at once. And, to some extent, the new theory presented here revises the understanding of AP. That is, because any gene can be triggered in an erroneous manner, every gene is potentially an AP gene that risks pathology, though level of risk varies according to constraint. To help validate the theory, we test it against several complex diseases of aging. The new model in this review attempts to provide a blueprint understanding that, to a certain extent, closes the gap in the causal chain of events between evolutionary causes of aging and the aetiology of age-related diseases. It also helps to explain why certain disorders mimic accelerated aging and how interventions, such as the suppression of IIS and mTOR retard many aspects of aging; notably, though, unlike prior programmatic theories, the new theory is not mTOR-centric. Finally, it provides new perspectives on possible treatment of aging.

Preprint ARTICLE | doi:10.20944/preprints202006.0081.v2

Measuring Independent and Controlled Effects of Age at Marriage and Age at First Birth on Completed Family Size among women aged 45-59 in Zambia

Nkuye Moyo, Tina Nanyangwe-Moyo, Xiaochun Qiao, Jilei Wu, Xiaoying Zheng

Subject: Social Sciences, Demography Keywords: age at first marriage; age at first birth; completed family size; fertility

Online: 13 October 2020 (14:17:28 CEST)

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Background The link between age at marriage and first birth in explaining completed family size is not always direct, due to heterogeneity in circumstances, that compel individual women to marry or initiate childbearing at a particular age. We analyzed data for 1020 women aged 45-49 in 2014 of the 1965-1969 birth cohort from the 2013-14 Zambia Demographic and Health Survey (ZDHS). Methods We fitted a bivariate and multivariate multinomial logistic regression to establish the relationship between a mother’s age at first marriage and at first birth on completed family size (CFS). Chi-square test of proportions measuring differences in proportions and relative risk ratios (RRR) with confidence intervals at 95% are reported. Results Our results show that the average CFS was 6.7 (95% CI: 6.5 – 6.9) among women completing their reproductive span in 2014 with mean age at first marriage and birth being 18.3 years (95% CI: 18.0 – 18.5) and 18.9 years (95% CI: 18.7 – 19.1) respectively. Women marrying at younger ages and having their first birth at younger ages were more likely (RRR: 1.187; 95% CI: 1.138-1.239 and RRR: 0.195; 95% CI: 0.074-0.511 respectively) to have higher CFS than their compatriots that initiated both marriage and childbearing at or after age 22 controlling for covariates as presented in the controlled model. The independent effects model shows that the risk of having 1-3 children compared to 6 or more children was lower (RRR: 0.073; 95% CI: 0.009-0.611; RRR: 0.136; 95% CI: 0,046-0.402 and RRR: 0.421; 05% CI: 0.135-1.312) for women whose ages at first marriage were <15, 15-18 and 19-21 respectively relative to 22+. Women with 1-3 children were 2.5 times more likely to use contraception than women with 6 or more children. Conclusion Having no education, being a rural resident and having a medium household wealth all increase the risk of having higher CFS. Women that marry before age 19 have a higher likelihood of having 6 or more children by the end of their reproductive period. The study concludes that apart from a woman’s age at first marriage and first birth, a complex network of factors interact to determined CFS.

Preprint ARTICLE | doi:10.20944/preprints202404.0842.v1

Prognostic Value and Limits of Heart Rate and QT-Corrected in A Large Population

Paolo Giovanardi, Cecilia Vernia, Sara Roversi, Enrico Tincani, Giuseppe Spadafora, Federico Silipo, Claudio Giberti

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: electrocardiogram; QT corrected; Bazett; heart rate; all-cause death; mortality

Online: 12 April 2024 (09:54:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0779.v1

Automatic Classification of All-sky Nighttime Cloud Images Based on Machine Learning

Xin Zhong, Fujia Du, Yi Hu, Xu Hou, Zonghong Zhu, Xiaogang Zheng, Kang Huang, Zhimin Ren, Yonghui Hou

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: nighttime cloud image; observational astronomy; all-sky cameras; PSO; XGBoost

Online: 13 March 2024 (12:40:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202306.0796.v1

Ionic Conductivity of Li6PS5Cl0.5Br0.5 Argyrodite Electrolyte at Different Operating and Pelletizing Pressures and Temperatures

Joshua Dunham, Joshua Carfang, Chan-Yeop Yu, Raziyeh Ghahremani, Rashid Farahati, Siamak Farhad

Subject: Engineering, Energy And Fuel Technology Keywords: All-solid-State Battery; Argyrodite Electrolyte; Li6PS5CL0.5Br0.5; Pelletizing; Pressure; Temperature

Online: 12 June 2023 (08:20:07 CEST)

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Preprint REVIEW | doi:10.20944/preprints202305.0620.v1

Acute Lymphoblastic Leukemia Immunotherapy Treatment: Now, Next, and Beyond

Anna Aureli, Beatrice Marziani, Adriano Venditti, Tommaso Sconocchia, Giuseppe Sconocchia

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: ALL; immunotherapy; antibody-drug conjugate; CAR-based therapies, targeted therapies

Online: 9 May 2023 (09:03:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202302.0414.v1

All-Cause Mortality According to COVID-19 Vaccination Status: an analysis of the UK Office for National Statistics Public Data

Alberto Donzelli, Giovanni Malatesta, Giovanni Di Palmo, Marco Cosentino, Marco Alessandria

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: COVID-19; COVID-19 vaccinations; all-cause mortality; relative risk

Online: 24 February 2023 (02:03:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints201911.0238.v1

An All-Weather Land Surface Temperature Product Based on MSG/SEVIRI Observations

Joao Paulo A. Martins, Isabel Trigo, Nicolas Ghilain, Carlos Jimenez, Frank-M. Goettsche, Sofia L. Ermida, Folke Olesen, Françoise Gellens-Meulenberghs, Alirio Arboleda

Subject: Environmental And Earth Sciences, Environmental Science Keywords: land surface temperature; all-weather; infrared; microwave; surface energy balance

Online: 20 November 2019 (11:12:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1898.v1

Regional-Scale Paleo–Proterozoic Heating Event on Archean Acasta Gneisses in Slave Province, Canada: Insights from K–Ar and 40Ar/39Ar Chronology

Megumi Sato, Hironobu Hyodo, Kei Sugiura, Tatsuki Tsujimori, Tetsumaru Itaya

Subject: Environmental And Earth Sciences, Geochemistry And Petrology Keywords: K-Ar age; 40Ar/39Ar age; biotite; amphibole; Acasta gneiss; Wopmay orogen; Canada

Online: 26 December 2023 (07:47:18 CET)

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Slave Province in Canada is an Archean granite-supracrustal terrane at the northwestern corner of the Canadian Shield. It is bordered by the Thelon–Taltson orogen (2.0 to 1.9 Ga) to the south-east and the Wopmay orogen (1.9 to 1.8 Ga) to the west. Acasta gneisses exposed in the western-most Slave province and the Wopmay rocks close to the gneisses were collected systematically for K-Ar and laser step-heating 40Ar /39Ar analyses of the biotite and amphibole. The K-Ar biotite ag-es of the four Wopmay samples range from 1816 ± 18 Ma to 1854 ± 26 Ma, which is within the reported U-Pb zircon age range of the Wopmay orogen. The K-Ar biotite ages of the fifteen Acasta gneisses range from 1779 ± 25 Ma to 1877 ± 26 Ma, except for a younger sample (1711 ± 25 Ma). The 40Ar/39Ar biotite analyses of the three samples from the Wopmay orogen give the plateau ages of 1826 ± 21 Ma, 1886 ± 13 Ma, and 1870 ± 18 Ma. On the other hand, the 40Ar/39Ar analyses of the biotite crystals from the Acasta gneiss show a variety of ages. Three samples show the plateau ages of 1877 ± 8 Ma, 1935 ± 14 Ma, and 1951 ± 11 Ma. These plateau ages are a little older than the total gas ages. The 40Ar/39Ar analyses of the amphibole crystals show more varied age rela-tions. The two samples show consistent age relations between the plateau ages (1814 ± 22 Ma and 1964 ± 12 Ma) and the total gas ages (1789 ± 23 Ma and 1967 ± 11 Ma), respectively. Some sam-ples have the apparent old age of 2000 Ma in the middle temperature fractions. These old frac-tions are due to that the originally existed amphibole crystals formed in Archean were affected by the thermal events during the Wopmay orogeny. but did not fully reset. The results suggest that the K-Ar system ages of the biotite and amphibole of the Archean Acasta gneiss that is aged from 4200 to 2600 Ma of zircon U-Pb ages were rejuvenated in the Paleo–Proterozoic ages. The heat source that rejuvenated the K-Ar system ages may have arisen due to the asthenospheric intrusion into the wedge mantle, which took place because of the subduction rollback.

Preprint ARTICLE | doi:10.20944/preprints202311.0373.v1

Sex-specific Relationships Between HDL-Cholesterol Levels and 10-year Mortality in Individuals with Atherosclerotic Cardiovascular Disease: A Nationwide Cohort Study of South Koreans

Hyun Suk Yang, Ho Jin Jeong, Hyeongsu Kim, Seungho Lee, Mina Hur

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: high-density lipoprotein cholesterol; atherosclerotic cardiovascular diseases; all-cause mortality; Biomarker

Online: 6 November 2023 (16:33:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202308.1433.v2

An Update on the Link between COVID-19 Vaccination and Mortality

Jarle Aarstad

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: COVID-19; full vaccination; booster vaccination; all-cause mortality; excess mortality

Online: 28 August 2023 (09:48:47 CEST)

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Preprint REVIEW | doi:10.20944/preprints202105.0296.v1

Clinical Performance of CAD/CAM All-ceramic Tooth-supported Fixed Dental Prostheses: A Systematic Review and Meta-analysis

Babak Saravi, Andreas Vollmer, Maja Hartmann, Gernot Lang, Ralf-Joachim Kohal, Martin Boeker, Sebastian B. M. Patzelt

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: CAD/CAM; dental restoration; ceramic; all-ceramic; survival; fixed dental prosthesis

Online: 13 May 2021 (13:18:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0163.v1

Ultraconserved Long Non-Coding RNA Uc.112 is Abnormally Expressed in Childhood Acute Lymphoblastic Leukemia Subtypes

Pablo Chagas, Graziella Sousa, Marcio Kodama, Carlos Biagi Junior, José Yunes Andres, Silvia Brandalise, George Calin, Luiz Tone, Carlos Scrideli, Jaqueline Oliveira

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: T-UCR; pediatric acute lymphoblastic leukemia; uc.112; T-ALL; hyperdiploidy.

Online: 8 October 2018 (17:01:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0199.v1

Sustainability Assessment of the Groundwater Quality in the Western India to Achieve Urban Water Security

Chitresh Saraswat, Pankaj Kumar, Prashant Bhalani

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Water Security; Water for all; Groundwater assessment; Groundwater quality; Water scarcity

Online: 14 May 2018 (16:01:09 CEST)

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Preprint REVIEW | doi:10.20944/preprints202308.0936.v1

Early Complications in the Era of ATRA Plus ATO Therapy Outside of Clinical Trials‐One Center Experience during Three Years and Literature Review‐

Ghiaur Alexandra, Cristina Doran, Bogdan Ionescu, Maria Camelia Stancioaica, Roxana Hirjan, Aurelia Tatic, Mihaela Cirstea, Mihaela Dragomir, Onda Calugaru, Codruta Popa, Cerasela Jardan, Didona Vasilache, Daniel Coriu

Subject: Medicine And Pharmacology, Hematology Keywords: acute promyelocytic leukemia; arsenic trioxide; all‐trans retinoic acid; non‐hematologic toxicities

Online: 14 August 2023 (09:52:50 CEST)

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Abstract The hallmark of acute promyelocytic leukemia (APL) is the presence of the characteristic fusion transcript of the promyelocytic leukemia gene with the retinoic acid receptor α gene (PML::RARA), which is a molecular target for all-transretinoic acid (ATRA) and arsenic trioxide (ATO). Therapies with ATRA plus ATO have excellent outcomes in terms of complete remission rate, overall survival, and achievement of a deep and durable molecular response with a very low incidence of relapse. However, although the combination of ATRA and ATO has lower hematologic toxicity than standard chemotherapy, its use is associated with a spectrum of unique toxicities, such as hepatic toxicity, QTc (QT interval corrected) prolongation, neurotoxicity, and differentiation syndrome. Hematologists treating patients with acute promyelocytic leukemia should be aware of possible early-complications of the ATRA plus ATO regimen and aim to balance treatment-related adverse events and efficacy. Careful follow-up of the patient’s clinical course is essential to identify and treat each complication. This study focused on treatment-related complications during induction and consolidations in patients with APL who received ATRA plus ATO. We retrospectively analyzed 26 adult patients diagnosed with APL between 2019 and 2022 at our center to identify the incidence rate, severity and time of onset of short-term non-hematologic adverse events relative to the initiation of the ATRA and ATO regimen. Additionally, we review the existing literature regarding the toxic side effects of ATO in APL and discuss how its most frequent toxicities should be managed. The median follow-up of our patients was 21.5 months (range, 1-48 months) and the most common adverse events were hepatic toxicity (69.2%), infections (46.1%), differentiation syndrome(23%) and QT prolongation (11.5%). All patients experienced at least one adverse event and grade 3 and 4 toxicities occurred in 57.6 % patients; these generally consisted of liver enzyme elevations, QTc prolongation, but also some rare manifestations such as musculoskeletal pain syndrome (1 patient) and ATO-related pancreatitis (1 patient). Most patients developed side-effects during induction. This is the first study about Romanian patients diagnosed with APL. Our results suggest that all treatment-related adverse events, except for differentiation syndrome are manageable, self-limiting and reversible. All patients, except for two (one died during induction and one died during consolidation), were able to complete the treatment consolidation with ATO and ATRA.

Preprint ARTICLE | doi:10.20944/preprints202305.1914.v1

Current Effect on the Performances of All-Solid-State Lithium-Ion Batteries. Peuckert’s Law

Alexander Rudy, Alexander Skundin, Victor Naumov, Alexander Mironenko

Subject: Chemistry And Materials Science, Electrochemistry Keywords: all-solid-state lithium-ion batteries; Peuckert’s law; battery model; Peuckert’s exponent

Online: 26 May 2023 (10:16:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0119.v1

Textural and Consumer-Aided Characterisation and Acceptability of a Hybrid Meat and Plant-Based Burger Patty

Bjørn Petrat-Melin, Svend Dam

Subject: Biology And Life Sciences, Food Science And Technology Keywords: plant-based; meat alternative; hybrid burger; check-all-that-apply; consumer survey.

Online: 3 May 2023 (09:10:03 CEST)

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Preprint SHORT NOTE | doi:10.20944/preprints202312.2223.v1

Breaking Back and Bones: A Review on Osteoporotic Vertebral Fracture

Leon Phoon, Dev Desai, Vismit Gami

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: Osteoporosis; Spinal Column; Fracture; Age; Treatment

Online: 29 December 2023 (11:57:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202302.0519.v1

The Effect on HbA1c Levels of Age and Gender in Adults Without Diabetes Mellitus

Gülşen Şener, Esra Deniz Kahvecioğlu, Başak Can, Alper Gümüş, Semih Beyazıt Yeşil, Betül Evran

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: Diabetes mellitus; HbA1c; gender; age; correlation

Online: 28 February 2023 (10:39:45 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202110.0386.v1

Causes and Treatment of Hypoxia During Total Hip Arthroplasty in Elderly Patients: Case Report

Jae Young Ji, Jin Hun Chung, Nan Seol Kim, Yong Han Seo, Ho Soon Jung, Hea Rim Chun, Hyung Yoon Gong, Woo Jong Kim, Jae Min Ahn, Yu Jun Park

Subject: Medicine And Pharmacology, Anesthesiology And Pain Medicine Keywords: Atelectasis; Hypoxia; Old age; Spontaneous respiration

Online: 26 October 2021 (12:36:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0245.v1

Post Vaccination Titers of Serum Anti-Diphtheria in Indonesian Young and Middle-Aged Adults

Gatot Soegiarto, Diksi Novritasari, Ari Baskoro, Deasy Fetarayani, Wita Kartika Nurani

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Age; Antibody titers; Diphtheria; Immunosenescence; Vaccine

Online: 12 July 2021 (11:33:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202102.0501.v1

Age-dependent Non-silent Somatic Mutation with Transcriptomic Landscape and Prognosis of Lower Grade Glioma

YoungJoon Park, JeongMan Park, Ju Won Ahn, JeongMin Sim, Su Jung Kang, Suwan Kim, Sojung Hwang, Kyoung Su Sung, Jaejoon Lim

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: age; glioma; mutation; TCGA; transcriptomic analysis

Online: 23 February 2021 (08:16:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202102.0029.v1

Gender, Age, Year of Course and Faculty: Factors Influencing the Risk of Eating Disorders

María-Camino Escolar-Llamazares, María-Ángeles Martínez-Martín, María-Begoña Medina-Gómez, María-Yolanda González-Alonso, Elvira Mercado-Val, Fernando Lara-Ortega

Subject: Social Sciences, Psychology Keywords: eating disorder; gender; age; university degree

Online: 1 February 2021 (12:58:08 CET)

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Preprint EDITORIAL | doi:10.20944/preprints201608.0130.v1

What Is the Main Cause of Cancer?

Miguel López-Lázaro

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: carcinogenesis; cancer; age distribution of cancer

Online: 11 August 2016 (11:40:40 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0484.v1

Recent Research Progress on All-Solid-State Mg Batteries

Jayaraman Pandeeswari, Gunamony Jenisha, Kumlachew Zelalem Walle, Masashi Kotobuki

Subject: Chemistry And Materials Science, Electrochemistry Keywords: magnesium battery; solid electrolyte; ceramic electrolyte; polymer electrolyte; all-solid-state Mg battery

Online: 10 October 2023 (02:55:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0579.v1

Probing the Analytical Cancelation Factor of Short Scale Gravity Waves Using Na Lidar and Nightglow Data from the Andes Lidar Observatory

Fabio Vargas, Javier Fuentes, Pedro Vega, Luis Navarro, Gary Swenson

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Airglow; All-Sky Imagery; Atmospheric Gravity Waves; Cancelation Factor; Lidar; Mesosphere-Lower-Thermosphere

Online: 28 October 2020 (10:06:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints201910.0273.v1

Growth Rate of Gravity Wave Amplitudes Observed in Sodium Lidar Density Profiles and Nightglow Image Data

Fabio Vargas, Guotao Yang, Paulo Batista, Delano Gobbi

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: all-sky imager; sodium lidar; gravity waves; mesosphere nightglow; growth rate; wave dissipation

Online: 24 October 2019 (05:46:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2104.v1

A New Species of Hemilauxania Hennig (Lauxaniidae) from the Lower Eocene Oise Amber—The Oldest Record of Schizophora (Diptera)?

Jindřich Roháček, Christel Hoffeins

Subject: Biology And Life Sciences, Insect Science Keywords: extinct lauxaniid flies; age of Acalyptratae; Paleogene

Online: 29 September 2023 (10:57:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1739.v1

Effects of Age and Season on Blood Parameters of Domesticated Giant Pandas

Ruijie Jiang, Xinyi Zhang, Kai Fan, Maohua Xia, Sufen Zhao, Yunsheng Wang, Tianchun Pu, Chenglin Zhang, Zhong Wu, Haihong Xu

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: giant pandas; seasonal; age; blood Indices; hemorheology

Online: 24 August 2023 (10:10:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.2052.v1

Artificial Intelligence Prediction of Gestational Age of Fetal in Brain Magnetic Resonance Imaging versus ultrasound Using three different Biometric Measurements

Farzan Vahedifard, Xuchu Liu, Kranthi K. Marathu, Mehmet Kocak, H. Asher Ai, Mark P. Supanich, Seth Adler, Shehbaz M. Ansari, Melih Akyuz, Jubril O. Adepoju, Sharon Byrd

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Artificial Intelligence; Gestational Age; Fetal Brain; MRI

Online: 31 July 2023 (03:07:23 CEST)

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Abstract: Accurately predicting a fetus's gestational age (GA) is of utmost importance in prenatal care. This study aimed to develop an artificial intelligence (AI) model that can automatically predict GA using biometric measurements derived from fetal brain mag-netic resonance imaging (MRI). Additionally, we aimed to assess the significance of con-sidering different references when interpreting GA predictions. To achieve this, we obtained measurements such as Biparietal Diameter (BPD), Fron-to-occipital Diameter (FOD), and Head Circumference (HC) from a dataset comprising 52 normal fetal MRI cases with T2 Haste sequences from Rush University. Both manual and AI-based methods were utilized to acquire these measurements. We also employed three reference papers (Garel, Freq, and Bio) for comparison purposes. The results demonstrated a strong correlation between manual and AI measure-ments, indicating consistency between the two methods. The AI-based measurement of HC exhibited a higher correlation with actual values compared to BPD, FOD, and correct-ed BPD (BPDC). When comparing these measurements with GA in the Picture Archiving and Communication System (PACS), the differences varied depending on the reference used. Specifically, the differences ranged from 0.47 to 2.17 weeks for BPD, 0.46 to 2.26 weeks for FOD, and 0.75 to 1.74 weeks for HC. Furthermore, the Pearson correlation coeffi-cient analysis revealed that all correlation coefficients between PACS records and GA pre-dictions using different references were greater than 0.97. In conclusion, the AI model based on fetal brain MRI accurately predicts GA by uti-lizing BPD, FOD, and HC measurements. The AI approach, which involves combining line segments to calculate fetal head circumference, offers improved accuracy and con-venience compared to manual estimation. This study underscores the potential of AI models in accurately estimating gestational age and highlights their utility in prenatal care. By integrating AI as a valuable tool in prenatal care, we can enhance the accuracy, ef-ficiency, and decision-making involved in assessing fetal development and monitoring pregnancies using MRI measurements.

Preprint ARTICLE | doi:10.20944/preprints202305.1956.v1

Characteristics of Mental Toughness in Young Basketball Players of Different Age Groups

Eimantas Pocius, Romualdas Malinauskas

Subject: Social Sciences, Psychology Keywords: mental toughness skills; young athletes; age groups

Online: 29 May 2023 (04:04:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0685.v1

Association of Metabolic Syndrome Components with Kidney Cancer in Young Adult Population : A Nationwide Population-Based Cohort Study in Korea

Hee Yeon Lee, Kyung-Do Han, In Sook Woo, Hyuk-Sang Kwon

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: Kidney cancer; Metabolic syndrome; Age; Young adults

Online: 10 May 2023 (04:38:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0868.v1

The Relationship between Number of Supernumerary Blastocysts Cryopreserved and Probability of a Live Birth Outcome after Single Fresh Blastocyst Transfer: Analysis of over 10 Thousand Cycles

Yusuf Beebeejaun, Timothy Copeland, Lukasz Polanski, Tarek El Toukhy

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: IVF; blastocyst transfer; cryopreservation; live birth; age

Online: 25 April 2023 (03:01:55 CEST)

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The ability to predict the likelihood of a live birth after single fresh embryo transfer is important for treatment planning and managing patient expectation, particularly in their first in vitro fertilization (IVF) cycle. Cryopreservation of supernumerary embryos is often regarded as an important prognostic variable and a surrogate marker of success for several reasons. While previous large studies have examined the association between the number of oocytes retrieved and cleavage-stage embryos available, and the odds of a live birth following a fresh embryo transfer, the relationship between the number of supernumerary blastocysts cryopreserved following a fresh embryo transfer has not been rigorously studied. We performed a retrospective analysis of data collected between 2006 and 2018 for all first time IVF patients with a fresh autologous day 5 single blastocyst transfer. The relationship between the likelihood of a live birth and number of supernumerary blastocysts cryopreserved was assessed according to patient age group. In patients aged <35 years and 35-39 years old, the likelihood of a live birth increased linearly from 0.33 (95%CI:0.31–0.34) to 0.80 (95%CI:0.74–0.86; P<.0001) and 0.30 (95%CI:0.28–0.32) to 0.82 (95%CI:0.73–0.91;P<.0001) between 1-6 blastocysts cryopreserved and then non-linearly to 0.95 (95% CI 0.92–0.97; P<.0001) and 0.96 (95%CI:0.93–0.99; P<.0001) if 10 or more blastocysts were cryopreserved, respectively. When aged 40 years and above, the likelihood of a live birth increased linearly from 0.26 (95%CI:0.19–0.32) to 0.83 (95%CI:0.68–0.97; P<.0001) between 1-4 blastocysts cryopreserved and then non-linearly to 0.99 (95%CI:0.98–0.99; P<.0001) if 10 or more blastocysts were cryopreserved. The present study demonstrated a non-linear relationship between the number of supernumerary blastocysts cryopreserved and the likelihood of a live birth after single blastocyst transfer in the first autologous fresh IVF/ICSI cycle across different age groups.

Preprint ARTICLE | doi:10.20944/preprints202201.0019.v1

Glacier Recession in Altay Mountains after the LIA Maximum

Dmitry Ganyushkin, Kirill Chistyakov, Ekaterina Derkach, Dmitriy Bantcev, Elena Kunaeva, Anton Terekhov, Valeriia Rasputina

Subject: Environmental And Earth Sciences, Environmental Science Keywords: glaciers; Little Ice Age; reconstruction; retreat; Altai

Online: 4 January 2022 (20:30:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202103.0210.v1

Metabolomic Characterization of Olive Xylem Sap Reveals Differences According to Plant Age and Genotype

Manuel Anguita-Maeso, Carmen Haro, Miguel Montes-Borrego, Leonardo De La Fuente, Juan A. Navas-Cortés, Blanca B. Landa

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: olive; xylem sap; metabolomics; plant age; genotype

Online: 8 March 2021 (10:56:37 CET)

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Vascular pathogens are the causal agents of main diseases threatening the health and growth of olive crops worldwide. The use of endophytic microorganisms represents a challenging and promising strategy for management of vascular diseases in olive. Although current research has been focused on analyzing the structure and diversity of the endophytic microbial communities inhabiting the olive xylem, the characterization of this ecological niche has been overlooked and to date remain unexplored, despite that the characterization of the xylem sap composition is essential to unravel the nutritional requirements of xylem-limited microorganisms. In this study, branches from plantlets and adult olive trees of cultivars ‘Picual’ and ‘Arbequina' were selected to characterize the chemical composition of olive xylem sap extracted using a Scholander pressure chamber. Metabolome and ionome analyses of xylem sap were performed by proton nuclear magnetic resonance (NMR) spectroscopy-based and by inductively coupled plasma with optical emission spectroscopy (ICP-OES), respectively. Olive xylem sap metabolites included a higher relative percentage of sugars (54.35%), followed by alcohols (28.85%), amino acids (8.01%), organic acids (7.68%) and osmolytes (1.12%). Within each of these groups, the main metabolites in the olive xylem sap were mannitol, ethanol, glutamine, acetate and trigonelline, whereas K and Cl- were the main element and inorganic anion, respectively. Metabolomic profile varied when comparing olive plant age and genotype. The levels of glucose, fructose, sucrose and mannitol, choline, B and PO43 were significantly higher in adult trees than in plantlets for both olive genotypes, whereas NO3- and Rb content showed the opposite behavior. On the other hand, levels of aspartate, phenylalanine and Na were significantly higher in ‘Picual’ than in ‘Arbequina’ whereas Fe showed the opposite behavior but only for adult trees. Non-supervised hierarchical clustering analysis separated xylem sap composition firstly according to the plant age and then by the olive cultivar. Supervised PLS-DA analysis revealed that B, ethanol, Fe, Fructose, glucose, mannitol, sucrose and Sr were the most significative compounds discriminating adult trees from plantlets, whereas asparagine, aspartate, glutamate and phenylalanine or aspartate, arginine, ethanol and Sr were the most contributory compounds in the discrimination of both olive genotypes for adult trees or plantlets, respectively. Knowledge of the chemical composition of xylem sap will lead to a better understanding of the complex nutritional requirements of olive xylem-inhabiting microorganisms, including its vascular pathogens, and would allow the design of artificial growing media to improve culturing the olive microbiome.

Preprint ARTICLE | doi:10.20944/preprints201808.0025.v1

Health and Aging: Unifying Concepts, Scores, Biomarkers and Pathways

Georg Fuellen, Ludger Jansen, Alan A. Cohen, Walter Luyten, Manfred Gogol, Andreas Simm, Nadine Saul, Francesca Cirulli, Alessandra Berry, Peter Antal, Rüdiger Köhling, Steffen Möller

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: terminology, health, aging, biological age, wellbeing, biomarker

Online: 1 August 2018 (15:00:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202302.0350.v1

Is there a Link between the 2021 COVID-19 Vaccination Uptake in Europe and 2022 Excess All-Cause Mortality?

Jarle Aarstad, Olav Andreas Kvitastein

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: COVID-19; vaccination; all-cause mortality; excess mortality; causal inferences; ecological fallacy; individualistic fallacy

Online: 21 February 2023 (03:49:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202010.0271.v1

Regional Variations in the Dynamics of the COVID-19 Pandemic in the US

Gal Almogy

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: 2019-nCoV; COVID-19; excess mortality; all-cause deaths; case fatality ratio; CFR; epidemiology

Online: 13 October 2020 (10:27:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201911.0254.v1

Mean Zonal Drift Velocities of Plasma Bubbles Estimated from Keograms of Nightglow All-Sky Images from the Brazilian Sector

Fabio Vargas, Christiano Brum, Pedrina Terra, Delano Gobbi

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: all-sky imager; ionospheric plasma bubble; zonal drift velocity; keograms; nightglow; OI6300 thermospheric emission

Online: 22 November 2019 (05:42:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints201802.0045.v1

New Solvent for Polyamide 66 and its use for Preparing Single-Polymer Composite Coated-Fabric

Mostafa Jabbari, Parviz Rashidi Ranjbar, mikael skrifvars, Dan Åkesson, Mohammad J. Taherzadeh

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: Polyamide solvent, composite, coated-fabric, Nylon, single-polymer composite, all-polyamide composite coated-fabric

Online: 5 February 2018 (16:19:09 CET)

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Preprint REVIEW | doi:10.20944/preprints202310.1771.v1

Evidence of Age Estimation Procedures in Forensic Dentistry: Results from an Umbrella Review

João Albernaz Neves, Luísa Bandeira Lopes, Vanessa Machado, João Botelho, Ana Delgado, José João Mendes

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: forensic dentistry; age estimation; dental maturation; umbrella review

Online: 27 October 2023 (09:26:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.1105.v1

MethylRAD-Seq Technology Reveals DNA Methylation Charac-Teristics of Apostichopus japonicus of Different Ages

Xinyu Yang, Lingshu Han, Qi Ye, Hao Wang, Jinyuan Zhang, Wenpei Wang, HaoRan Xiao, Yongjie Wang, Luo Wang, Jun Ding

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: MethylRAD-Seq; A. japonicus; body wall; age identification

Online: 18 October 2023 (08:21:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0990.v1

Lipid Profile in Children Born Small for Gestational Age

Justyna Zamojska, Katarzyna Niewiadomska-Jarosik, Beata Kierzkowska, Marta Gruca, Agnieszka Wosiak, Elżbieta Smolewska

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: children; lipid profile; cholesterol; small for gestational age

Online: 14 September 2023 (14:05:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0524.v1

From Immunosenescence to Aging Types – Establishing Reference Intervals for Immune Age Biomarkers by Centile Estimation

Peter Bröde, Maren Claus, Patrick D Gajewski, Stephan Getzmann, Edmund Wascher, Carsten Watzl

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: immunosenescence; biological age; biomarker; flow cytometry; longitudinal study

Online: 7 August 2023 (10:05:00 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.1115.v1

A Paradigm Shift in the Entertainment Industry in the Digital Age: A Critical Review

Dr. Bharat Dhiman

Subject: Arts And Humanities, Film, Radio And Television Keywords: media; digital media; entertainment; paradigm shift; digital age

Online: 15 June 2023 (09:40:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0738.v1

Effects of Physical Activity Program on Body Composition, Physical Performance, and Neuromuscular Strategies During Walking in Older Adults With Sarcopenic Obesity: Randomized Controlled Trial

Hamza FERHI, Sabri GAIED CHORTANE, Sylvain DURAND, Bruno BEAUNE, Sebastien BOYAS, Wael MAKTOUF

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: age; obesity; gait; physical activity; neuromuscular system; sarcopenia

Online: 12 June 2023 (03:02:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.2151.v1

A Class of Models That Support a Maximum Entropy Principle for Age Structure

Henri Laurie

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: Population dynamics; age structure; entropy; Maximum Entropy Principle

Online: 30 May 2023 (13:20:58 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202107.0075.v1

Accurate Epigenetic Aging in Bottlenose Dolphins (Tursiops Truncatus), an Essential Step in the Conservation of at-Risk Dolphins.

Ashley Barratclough, Cynthia R. Smith, Forrest M. Gomez, Theoni Photopoulou, Ryan Takeshita, Enrico Pirotta, Len Thomas, Abby M. McClain, Celeste Parry, Joseph A Zoller, Steve Horvath, Lori H Schwacke

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: DNA methylation; epigenetic aging; bottlenose dolphin; chronological age

Online: 5 July 2021 (07:59:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202009.0200.v1

Comparison of Gender, Age, and Body Mass Index Levels for Spatiotemporal Parameters of Bilateral Gait Pattern

Turki S. Abualait, Mohammad Ahsan

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: spatiotemporal parameters; gait; gender; age; Body Mass Index

Online: 9 September 2020 (07:12:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0367.v1

Epidemiological Characteristics of Early COVID-19 Case Outbreaks in Indonesia

Abu Bakar, Triyono Indrasiwi Kuncoroaji, Andy Lee, Shih-Chieh Lee, Valendriyani Ningrum

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Confirmed cases, case fatality rate, province, age, gender.

Online: 17 July 2020 (06:24:55 CEST)

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The initial outbreak of COVID-19 was first reported in Wuhan (China) during the latter part of December 2019. Indonesia has the fourth-largest population globally and reported the country’s first case of the virus on 2nd March 2020. The World Health Organisation (WHO) in addition to several neighbouring provinces and educational institutions within the region began questioning the Indonesian government upon the initial case reported. The objective of this study was to describe the epidemiological characteristics of the COVID-19 outbreak in Indonesia during March 2020. The data were collected from Indonesian government databases and non-government organisations (NGOs). The data were analysed using Microsoft Office 2019 (Excel) and Adobe Illustrator 2017 software, was used in drawing the map depicting the distribution of COVID-19 in Indonesia. As at 31st March 2020, a total of 1,528 people in Indonesia have been infected by COVID-19, in addition to 136 mortalities (CFR of 8.9%). Jakarta, as the principal capital of Indonesia, quickly has become the epicentre of the virus since this period. Most patient cases were attributed to those aged between 31 and 70 years (72.64%), with male patients (64.93%) representing the highest incidence of cases compared to female patients (35.07%). The number of ventilating machines was 3,326, with hospital numbers at 859. The distribution of cases depicting COVID-19 was mainly seen in urban areas compared to rural areas. Males compared to females, are at a higher risk of contracting COVID-19, including those aged below 30, between 30 and 60 or above. Indonesia also has the highest case fatality rate (CFR) with respect to mortalities in Southeast Asia and has the second-highest CFR globally. Similarly, while the number of ventilator machines as at 31st March 2020 were sufficient in meeting the growing number of COVID-19 cases in the country, it is possible that the government may need to increase the number of ventilators if the cases continue to escalate.

Preprint ARTICLE | doi:10.20944/preprints201911.0335.v1

Socio-Moral Development of Preschool Children: Aspects of Theory and Practice

Evgenia Korotaeva, Irina Chugaeva

Subject: Social Sciences, Psychology Keywords: social and moral education; preschool age; communitarian approach

Online: 27 November 2019 (08:46:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints201902.0106.v1

Comparative Assessment of Age, Growth and Food Habit of the Black-Chinned Tilapia, Sarotherodon melanotheron (Rüppell, 1852), from Closed and Open Lagoons, Ghana

Cephas Kwesi Zuh, Seth Mensah Abobi, Benjamin Betey Campion

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: Ghana; lagoon; tilapia; fish growth; otoliths; age; food

Online: 12 February 2019 (17:14:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints201810.0187.v1

Determining Oil Palm Stands Age Using Multi Temporal Images Analysis

Anggoro Cahyo Fitrianto, Doddy Mendro Yuwono, Arif Darmawan, Koji Tokimatsu

Subject: Environmental And Earth Sciences, Environmental Science Keywords: remote sensing; multi-temporal; Landsat; age; canopy; FCD

Online: 9 October 2018 (11:33:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201809.0122.v1

Spatial and Age Related Effects on Phytochemical Compounds of Ethanolic Extract of Gigantochloa scortechinii Rhizome

Johar Mohamed, Hazandy Abdul Hamid, Ahmad Ainuddin Nuruddin, Nik Muhammad Nik Abdul Majid

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: spatial; age-related; phytochemical; bamboo; rhizome; GC-MS

Online: 7 September 2018 (03:01:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201712.0137.v1

Gimbutas’ Smile – An Archaeology Led, Archaeogenetic Model

Bob Kenyon

Subject: Arts And Humanities, Archaeology Keywords: Archaeology; Archaeogenetic Model; Neolithic; Chalcolithic; Bronze Age; Migration

Online: 19 December 2017 (15:49:22 CET)

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Migrations are much more important than currently recognised, for explaining important patterns observed in the European archaeology record – according to this archaeology led model. At a high level, they explain the introduction of different farming, monument building, the spread of metalworking and patterns of trade and exchange. This paper presents an archaeogenetic model based on a strategic review of the Neolithic and Chalcolithic archaeology of Europe, alongside a review of recently published ancient DNA data. The model is archaeology led. It takes archaeology themes and proposes migratory events to explain them. Ancient DNA data and further archaeology evidence is then used to test these proposed migrations- to reject or refine them. The model introduces a new and more strategic way of looking at archaeological cultures - that updates early 20th century approaches to studying archaeology cultures, and integrates with the detailed ‘post processual’ studies of the late 20th Century. The model consists of seven maps – each showing multiple migration events – with key evidence to support each migration map. It proposes a new category of a ‘Black Sea’ related population that makes a major genetic contribution to the Middle Neolithic of Europe. The proposed migrations provide an explanation for the observed patterns of archaeology, for example: • multiple Neolithic migrations that introduced, farming and metalworking into Europe; • a major ‘Black Sea’ related ‘Middle Neolithic’ migration that carried advanced knowledge of astronomy that can be recognised in a variety of types of monument from the Neolithic through to Bronze Age Europe; and, • migrations of related cultures (‘supercultures’) that explain patterns of trade and exchange in Bronze Age western Europe. The model also provides ancient DNA and archaeology based support for the key aspects of Childe’s ‘dawn of civilisation’ in Europe and Egypt and Gimbutas’ ‘Old Europe’ and “three waves of migration from the Steppe”.

Preprint ARTICLE | doi:10.20944/preprints201709.0016.v1

Responses of Soil Microbial Communities to Robinia Pseudoacacia Plantations of Different Ages in A Loess Area

Bingxue Zhang, Rumeng Zhao, Boyuan Bi, Fengpeng Han

Subject: Biology And Life Sciences, Forestry Keywords: soil; Robinia pseudoacacia; PLFA; stand age; microbial community

Online: 5 September 2017 (15:28:05 CEST)

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Phospholipid fatty acids (PLFAs) can be used as biomarkers for qualitative and quantitative analyses of soil microbial community diversity. In this study, we collected soil samples at 10-cm intervals to a depth of 1 m from Robinia pseudoacacia plantations of four different ages (10, 15, 25 and 40 years) in a loess area and analysed the soil microbial community structure by PLFA analysis. A total of 97 PLFAs were detected in soils of R. pseudoacacia plantations of different ages. The individual PLFA contents gradually decreased in the 0- to 40-cm soil layers, with little variation in the 40- to 100-cm soil layers. The individual PLFAs were similarly distributed in the soils of R. pseudoacacia plantations of different ages, and there was a clear variation with stand age and soil depth. The individual PLFA contents in the 0- to 20-cm soil layers were highest for the 25-year-old plantation, while those in the 20- to 40-cm soil layers were relatively high for the 25- and 40-year-old plantations; the 16:0 content was the highest among individual PLFAs. The total PLFA content and the PLFA contents of different microbial groups [bacteria, fungi, Gram-positive bacteria (G⁺), Gram-negative bacteria (G^-) and actinomycetes] initially increased before decreasing in the soils of R. pseudoacacia plantations with increasing stand age, whereas these contents gradually decreased with increasing soil depth; the highest PLFA contents was found in the 25-year-old plantation. The total PLFA content and the contents of fungal, G^- and actinomycete PLFAs in the soils of R. pseudoacacia plantations differed significantly among stands of different ages in the 0- to 10-cm, 10- to 20-cm and 30- to 40-cm soil layers, while no significant differences were found in the 20- to 30-cm soil layers; the G⁺ and bacterial PLFAs contents in each of the 0- to 40-cm soil layers were significantly different. The PLFA ratios between different microbial groups differed among the stands of different ages. The fungi/bacteria ratio showed a “decrease-increase-decrease” trend with stand age, while the G⁺/G^- ratio showed an “increase-decrease” trend. The saturated/monounsaturated PLFA ratio initially decreased before plateauing, while the opposite trend was observed for the cyclopropyl/precursor ratio. The PLFA contents of different microbial groups were ranked as follows: bacteria > G^- > G⁺ > actinomycetes > fungi. In the principle component analysis, 18:1ω9c, 10Me18:0, i17:0, a17:0, 18:1ω7c, 18:1ω5c and 18:0 made the greatest contribution to principal component 1, and a14:0, i14:0 3OH, i14:0, i14:1ω7c and 14:0 made the greatest contribution to principal component 2. In conclusion, soil nutrient status and other soil eco-environmental stress factors should be considered in 10- to 25-year-old (particularly ~15-year-old) plots for the management of R. pseudoacacia plantations to prevent forest soil degradation and improve forest stand quality, thereby achieving better soil and water conservation and environmental improvement in R. pseudoacacia plantations.

Preprint COMMUNICATION | doi:10.20944/preprints202309.0915.v1

Asymmetric Orthogonal Metasurfaces Governed by Toroidal Dipole Bound States in the Continuum

Jun Ji, Xiaolong Lv, Xiaoyuan Yang, Yunsheng Guo

Subject: Physical Sciences, Optics And Photonics Keywords: metasurface; all-dielectric metasurface; bound states in the continuum; TD-BIC; Fano resonance; Q factor

Online: 13 September 2023 (16:18:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0239.v1

Gray Public Space Under Urban Bridge - A Case Study of Public Arts Space Micro-Transformation Focusing on "Regional Culture" and "Art for All"

Ting Liu Liu, Wu Cao, Yuyi Liu

Subject: Arts And Humanities, Art Keywords: Urban grey space; Space under bridge; Public Art; Micro-transformation; Regional culture; Art for all

Online: 26 April 2022 (10:55:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202201.0227.v1

Enhancing Race and Ethnicity using Bayesian Imputation in an All Payer Claims Database

Sanae El Ibrahimi, Michelle A. Hendricks, Sara E Hallvik, Nazanin Dameshghi, Christi Hildebran, Michael A. Fischer, Scott G. Weiner

Subject: Social Sciences, Behavior Sciences Keywords: Bayesian inference; race and ethnicity imputation; All Payer Claims Database; vital statistics death records; validation

Online: 17 January 2022 (12:40:15 CET)

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Preprint REVIEW | doi:10.20944/preprints202109.0094.v1

Barriers and Challenges Going From Conventional to Cryogenic Superconducting Propulsion for Hybrid and All-Electric Aircrafts

F. Ferreira da Silva, João F. P. Fernandes, P. J. da Costa Branco

Subject: Engineering, Electrical And Electronic Engineering Keywords: Review; Electrical Machines; Superconducting Machines; Hybrid-Electric Aircraft; Propulsion Design; All-Electric Aircraft; Specific Power

Online: 6 September 2021 (13:04:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202011.0192.v1

On the Generalization Ability of Data-Driven Models in the Problem of Total Cloud Cover Retrieval

Mikhail Krinitskiy, Marina Aleksandrova, Polina Verezemskaya, Sergey Gulev, Alexey Sinitsyn, Nadezhda Kovaleva, Alexander Gavrikov

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Total cloud cover; all-sky camera; algorithms assessment; neural networks; machine learning; data-driven approach

Online: 4 November 2020 (10:55:10 CET)

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Total cloud cover (TCC) retrieval from ground-based optical imagery is a problem being tackled by a few generations of researchers. The number of human-designed algorithms for the estimation of TCC grows every year. However, there is not very much progress in terms of quality, mostly due to the lack of systematic approach to the design of the algorithms, to the assessment of their generalization ability, and to the assessment of the TCC retrieval quality. In this study, we discuss the optimization nature of data-driven schemes for TCC retrieval. In order to compare the algorithms, we propose the framework for the assessment of the algorithms characteristics. We present several new algorithms that are based on deep learning techniques: a model for outliers filtering, and a few models for TCC retrieval from all-sky imagery. For training and assessment of data-driven algorithms of this study, we present the Dataset of All-Sky Imagery over the Ocean (DASIO) containing over one million of all-sky optical images of visible sky dome taken in various regions of the World Ocean. The research campaigns contributed to DASIO collection took place in the Atlantic ocean, the Indian ocean the Red and Mediterranean seas, and also in the Arctic ocean. Optical imagery collected during these missions are accompanied by standard meteorological observations of cloudiness characteristics made by experienced observers. We assess the generalization ability of the presented models in several scenarios that differ in terms of the regions selected for the train and validation subsets. As a result, we demonstrate that our models based on convolutional neural networks deliver superior quality compared to all previously published schemes. As a key result, we demonstrate considerable drop of the ability to generalize the training data in case of strong covariate shift between training and validation subsets of imagery which may take place in case of region-aware subsampling.

Preprint ARTICLE | doi:10.20944/preprints202404.1085.v1

Preparation and hydration properties of sodium silicate-activated municipal solid waste incineration bottom ash composite slag cementitious materials

Juan Deng, Guoxiong Wu, Yuchao Xia, Li Liu

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: MSWIBA, sodium silicate-activated, hydration properties, equivalent age modeling

Online: 17 April 2024 (08:06:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0025.v1

Analysis of the Evolution of Water Quality in Tanks according to the Connections and Operation Mode. Application to the most Suitable Design

Marta Hervás, Fernando Martínez-Alzamora, Pilar Conejos

Subject: Engineering, Civil Engineering Keywords: Simulation; water quality; water age; storage tanks; hydraulic networks

Online: 1 April 2024 (10:33:25 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202401.1332.v1

Influence of the Age of Free-Living Amoeba Cysts on Their Vertical Distribution in a Water Column

Zineb Fechtali-Moute, Sébastien Pomel

Subject: Biology And Life Sciences, Life Sciences Keywords: Free-Living Amoeba; cyst; age; water column; vertical distribution

Online: 17 January 2024 (13:38:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0040.v1

Discrete-time Survival Models with Neural Networks for Age-Period-Cohort Analysis of Credit Risk

Hao Wang, Anthony Graham Bellotti, Rong Qu, Ruibin Bai

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Credit risk; Survival model; Neural network; Age-Period-Cohort

Online: 3 January 2024 (03:53:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0166.v1

Knowledge Representation of Age-Related Diseases under Innate and Adaptative-Immunosenescence Valued Contexts

javier Burgos-Salcedo

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Immunosenescence; Knowledge representation; Formal concept Analysis; Age-related diseases

Online: 4 December 2023 (11:27:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1534.v1

Mitigating Age-related Bias in Predictive Policing Algorithms

Ahmed Saud Almasoud

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: predictive policing; algorithms; fairness; age bias; strategic subject list

Online: 24 November 2023 (02:42:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1581.v1

Could the Combination of eGFR and mGPS Facilitate the Differential Diagnosis of Age-Related Renal Decline from Diseases? A Large Study on the Population of Western Sicily

Miriam Carella, Annamaria Porreca, Cinzia Piazza, Francesco Gervasi, Daniele Magro, Marika Venezia, Raffaella Lo verso, Giuseppe Vitale, Anna giusy Agnello, Tommaso Aronica, Carmela Rita Balistreri

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: renal age-related decline; kidney disease (KD); eGFR; mGPS

Online: 25 October 2023 (08:35:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.1249.v1

The Relationship between Jealousy and Mate Retention Strategies in Romantic Relationships among Women during the COVID-19 Pandemic

Paulina Degiuli, Lea Andreis, Dario Vučenović

Subject: Social Sciences, Psychology Keywords: jealousy; partner retention strategies; romantic relationship; age; relationship length

Online: 20 October 2023 (08:06:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0658.v2

Assessment of Knowledge and Attitude of Reproductive Age Women towards Cervical Cancer Prevention in Selected Tertiary Institutions in Osun State, Nigeria

Oluwabunmi B. Erinsakin, Adeyemi O. Omoge, Oladunni Opeyemi, Idowu A. Olumakinde, Busayomi E. Folashayo, Michael N. Philip

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Knowledge; Attitude; Women of Reproductive Age; Cervical Cancer Prevention

Online: 17 October 2023 (11:47:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1322.v1

Age and Task Modulate Olfactory Sensitivity in the Florida Carpenter Ant Camponotus floridanus

Stephen T Ferguson, Isaac Bakis, Nicholas D Edwards, Laurence J Zwiebel

Subject: Biology And Life Sciences, Insect Science Keywords: hymenoptera; olfaction; odor coding; task allocation; age polyethism; aging

Online: 19 July 2023 (10:03:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0469.v1

Dynamical Analysis of an Age-Structured Sveir Model With Imperfect Vaccine

Yanshu Wang, Hailiang Zhang

Subject: Computer Science And Mathematics, Mathematical And Computational Biology Keywords: SVEIR model; latent age; imperfect vaccine; Lyapunov functions; stability

Online: 7 June 2023 (02:32:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0832.v1

Age of Onset Moderates the Association Between Total Antioxi-Dant Capacity and Cognitive Deficits in Patients With Drug-Naïve Schizophrenia

Jiaxin Li, Deyang Li, Junru Guo, Dongmei Wang, Xiangyang Zhang

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: schizophrenia; age of onset; TAOC; cognitive function; oxidative stress

Online: 24 April 2023 (06:22:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0152.v1

Eugenio Martelli, Matilde Zamboni, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe Massimo Sangiorgi, Mariangela Valentina Puci, Allegra Rosa Martelli, Teresa Messina, Paolo Frigatti, Maria Pia Borrelli, Carlo Ruotolo, Ilaria Ficarelli, Paolo Rubino, Francesco Pezzo, Luciano Carbonari, Andrea Angelini, Edoardo Galeazzi, Luca Calia Di Pinto, Franco Michelino Fiore, Armado Palmieri, Giorgio Ventoruzzo, Giulia Mazzitelli, Franco Ragni, Antonio Bozzani, Enzo Forliti, Claudio Castagno, Pietro Volpe, Mafalda Massara, Diego Moniaci, Elisa Pagliasso, Tania Peretti, Mauro Ferrari, Nicola Troisi, Pietro Modugno, Maurizio Maiorano, Umberto Marcello Bracale, Marco Panagrosso, Mario Monaco, Giovanni Giordano, Giuseppe Natalicchio, Antonella Biello, Giovanni Maria Celoria, Alessio Amico, Mauro Di Bartolo, Massimiliano Martelli, Roberta Munaó, Davide Razzano, Giovanni Colacchio, Francesco Bussetti, Gaetano Lanza, Antonio Cardini, Bartolomeo Di Benedetto, Mario De Laurentis, Maurizio Taurino, Pasqualino Sirignano, Pierluigi Cappiello, Andrea Esposito, Santi Trimarchi, Silvia Romagnoli, Andrea Padricelli, Giorgio Giudice, Adolfo Crinisio, Giovanni Di Nardo, Giuseppe Battaglia, Rosario Tringale, Salvatore De Vivo, Rita Compagna, Valerio Stefano Tolva, Ilenia D'Alessio, Ruggiero Curci, Simona Giovannetti, Giuseppe D'Arrigo, Giusi Basile, Dalmazio Frigerio, Gian Franco Veraldi, Luca Mezzetto, Arnaldo Ippoliti, Fabio Massimo Oddi, Alberto Maria Settembrini

Subject: Medicine And Pharmacology, Hematology Keywords: chronic limb-threatening ischemia; outcome; sex; age; limb salvage

Online: 8 December 2022 (09:39:30 CET)

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Preprint REVIEW | doi:10.20944/preprints202211.0350.v2

Recent Advances in Proteomic-based Approaches to Study Age-related Macular Degeneration: A Systematic Review

Laura García-Quintanilla, Lorena Rodríguez-Martínez, Enrique Bandín-Vilar, María Gil-Martinez, Miguel González-Barcia, Cristina Mondelo-García, Anxo Fernández-Ferreiro, Jesús Mateos

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Proteomics, Age-related macular degeneration, inflammation, biomarker, oxidative stress.

Online: 21 November 2022 (02:35:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202210.0278.v1

Association between Knowledge about Anemia, Food Consumption Behaviors, and Hematocrit Level among School-Age Children in Nakhon Si Thammarat Province, Thailand

Pastraporn Kaewpawong, Kiatkamjorn Kusol, Onuma Bunkarn, Sirigran Sutthisompohn

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: knowledge; food consumption behaviors; hematocrit level; school-age children

Online: 19 October 2022 (10:06:28 CEST)

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Anemia is a significant public health problem among children, especially school-age children because their body quickly produces red blood cells to provide sufficient blood volume with plasma expansion to maintain blood concentration. This research aimed to study the anemia situation, knowledge about anemia, food consumption behaviors, and the association between knowledge, food consumption behaviors, and hematocrit level among school-age children in primary school, in Thasala district, Nakhon Si Thammarat Province. This is a descriptive study among 408 students, Grades 4 to 6, aged 9-12 years. Research instruments included the demographic data of the children and their knowledge about anemia, food consumption behaviors, and hematocrit assessment. Data were analyzed using descriptive, Spearman’s rank correlation coefficient, and logistic regression statistics. The results revealed that 23.2% of the samples had anemia, whereas 22.22% had mild anemia and 0.98% had moderate anemia. The children knew about anemia, where the mean score was at a moderate level (Mean= 6.63; SD= 2.51) out of 10. The mean score on food consumption behaviors was in the moderate level (Mean= 17.49; SD= 3.68) out of 24. There were significantly positive correlations between the knowledge about anemia and the hematocrit level at a moderate level (r= 0.45, p< 0.001). Correlation analysis revealed moderate food consumption behaviors with the hematocrit level (r= 0.40, p< 0.001). When confirm with Logistic regression found that knowledge about anemia (OR = 9.15, 95% CI: 4.57-18.34), and food consumption behaviors (OR = 19.09, 95% CI: 9.71-37.53) were significantly associated with the hematocrit level. Conclusions: This study showed that knowledge and appropriate food consumption behaviors are associated with hematocrit levels. Enhancing knowledge about anemia and food consumption behaviors may be reduced the prevalence of anemia in school-age children. The health care providers in primary care should be encouraged children to have health education and eat sufficient food.

Preprint ARTICLE | doi:10.20944/preprints202206.0091.v1

Assessing the Effectiveness of Tobacco 21 Laws to Reduce Underage Access to Tobacco: Protocol for a Repeated Multi-Site Study

Mary Hrywna, Amanda Kong, Christopher Ackerman, Shawna Hudson, Cristine Delnevo

Subject: Public Health And Healthcare, Health Policy And Services Keywords: tobacco age of sale; tobacco policy; youth; young adults

Online: 7 June 2022 (03:44:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0367.v1

Differences in Citation Patterns across Areas, Article Types and Age Groups of Researchers

Marcelo Mendoza

Subject: Social Sciences, Library And Information Sciences Keywords: Citation patterns; Age groups of researchers; Types of publications.

Online: 17 August 2021 (15:09:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0434.v1

Clinical and Laboratory Characteristics of Kikuchi-Fujimoto Disease According to Age

Hye-Young Kim, Ha Young Jo, Seong Heon Kim

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Kikuchi-Fujimoto disease; histiocytic necrotizing lymphadenitis; prognosis; children; age

Online: 20 July 2021 (09:37:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0729.v1

Sergey Sudakov, Elena Alekseeva, Galina Nazarova, Valentina Bashkatova

Subject: Social Sciences, Psychology Keywords: age; behaviour; open field; physical activity; anxiety; Wistar rat.

Online: 30 June 2021 (10:57:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0536.v1

“What a Mobility-Limited World”: Design Requirements of an Age-Friendly Playable City

Liliana Vale Costa, Ana Isabel Veloso, Michael Loizou, Sylvester Arnab, Richard Tomlins, Arun Sukumar

Subject: Social Sciences, Urban Studies And Planning Keywords: playable city; age-friendly environments; games; mobility; active ageing

Online: 23 October 2018 (10:11:15 CEST)

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