Classic game theory is an important field with a long tradition of useful results. Recently, the quantum versions of classical games, such as the Prisoner's Dilemma (PD), have attracted a lot of attention. Similarly, state machines and specifically finite automata have also been under constant and thorough study for plenty of reasons. The quantum analogues of these abstract machines, like the quantum finite automata, have been studied extensively. In this work, we examine some well-known game conditional strategies that have been studied within the framework of the repeated PD game. Then, we try to associate these strategies to proper quantum finite automata that receive them as inputs and recognize them with probability 1, achieving some interesting results. We also study the quantum version of PD under the Eisert-Wilkens-Lewenstein scheme, proposing a novel conditional strategy for the repeated version of this game.

The work proposes a new approach for evolutionary global optimization which, in simple terms, may be described as a fusion of quantum and simulated annealing. This becomes possible by using basic concepts from Homotopy Theory, conjugated to the already existing Fuzzy Adaptive Simulated Annealing paradigm and other components. In this fashion, it occurs a temporal and nonlinear superposition of the two types of annealing, provoking interesting effects in runtime, including the so-called quantum tunneling, when there is a sudden transition between attraction basins of different minima without "climbing" potential barriers. In addition, the proposal includes a generalization of the "deformation" of Hamiltonians used in quantum annealing by suggesting the use of general homotopies between the surface corresponding to the cost function under processing and another specific landscape, being this possible because of the ability of Fuzzy ASA of handling time-varying objective functions. The proposed paradigm shows that it is possible and beneficial to superpose the two types of annealing, displaying amazing numerical results and suggesting a kind of interlacing or synergic behavior - perhaps we could call it an "annealing entanglement". Finally, given the fast advances in commercial quantum annealing processors, it seems sensible to expect that an implementation of the proposed approach using such devices may occur very soon. In order to demonstrate the efficacy of the proposed algorithm, some significant and detailed examples are included in the text, so as to illustrate and clarify the presented ideas.

We describe cosmic expansion from the standpoint of an observer’s comoving horizon. When the Universe is small, the observer detects a large amount of the total cosmic bits, which number is fixed. Indeed, information, such as energy, cannot be created or destroyed in our Universe, i.e., the total number of cosmic bits must be kept constant, despite the black hole paradox. When the Universe expands, the information gets ergodically “diluted” in our isotopic and homogeneous Cosmos. This means that the observer can perceive just a lower number of the total bits, due the decreased density of information in the cosmic volume (or its surrounding surface, according to the holographic principle) in which she is trapped by speed light’s constraints. Here we ask: how does the second law of thermodynamics enter in this framework? Could it be correlated with cosmic expansion? The correlation is at least partially feasible, because the decrease in the information detected by a local observer in an expanding Universe leads to an increase in detected cosmic thermodynamic entropy, via the Bekenstein bound and the Laudauer principle. Reversing the classical scheme from thermodynamic entropy to information entropy, we suggest that the quantum vacuum’s cosmological constant, that causes cosmic expansion, could be one of the sources of the increases in thermodynamic entropy detected by local observers.

The long-term laboratory aspects of the effects of COVID-19 on liver function are still not well understood. Therefore, this study aimed to evaluate the hepatic clinical-laboratory profile of patients with up to 20 months of long-term COVID-19. A total of 243 patients of both sexes aged 18 years or older hospitalised in the acute phase of COVID-19 were included in this study. Liver function analysis was performed. Changes were identified in the mean levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), gamma-glutamyl transferase (GGT), and ferritin. Inflammatory markers such as ferritin > 300 U/L were observed in the group that presented more changes in liver function markers (ALT, AST, and GGT). Age ≥ 60 years, male sex, AST > 25 U/L, and GGT ≥ 50 or 32 U/L were associated with ALT > 29 U/L. There was a correlation between ALT and AST, LDH, GGT, and ferritin. Our findings suggest that ALT and AST levels may be elevated in patients with long-term COVID, especially in those hospitalised in the acute phase. In addition, ALT > 29 U/L was associated with other markers of liver injury, such as LDH, GGT, and ferritin.

Background and Objectives: Due to huge demand and availability of Banana, innovative cost effective method is necessary to promote and smoothen the banana production among farmers commercially mitigating the demand. Method and Materials: In this study, we feed cow dung mixture along with Urea, TSP, MoP, water to the distal part of rachis after cutting down male bud as soon as the female flowers matured into fruits (T1). The effect of this method was then compared with two control groups; one with the same strategy except fertilizer applied on root following ring method (C1, Positive control) and another was male flower untouched without applying fertilizer on rachis or root (C2, Negative control). Results and Conclusion: T1 showed more than double increase in length than controls. In the same way, in case of shape (diameter), T1 (0.46 cm) showed twice as better growth in the C1 (0.22 cm) and C2 (0.18 cm). Trend analysis showed the test group T1 curve is much steeper than the control groups suggesting faster growth rate than the other two. Finally, the cost of fertilizers for T1 per plant was estimated 0.091 USD while for positive control C1 it was 2.9 USD. This study shows an approach to be effective and economic comparing to traditional method of fertilizer application, which can be adapted as a new method of banana production.

In this paper, we investigate the Hawking radiation process by using the quantum tunneling phenomenon of massive spin-1 (W-bosons) and spin-0 particles from (2+1) dimensional Black Hoke with quintessential and magnetic field. For this purpose, using Hamilton-Jacobi ansatz, we apply the WKB approximation to the field equations of massive charged vector particles. We get the required tunneling rate of radiated particles and obtain their corresponding Hawking temperature $T_h$. In order to study the quantum gravity effects, we utilize the generalized Proca and Klein-Gordan equations incorporating the generalized uncertainty principle (GUP) and recover the accompanying quantum corrected temperature $T'_{h}$.

We introduce a number of techniques in quantitative convergent-beam electron diffraction under development by our group and discuss the basis for measuring interatomic electrostatic potentials (and therefore also electron densities), localised at sub-nanometre scales, with sufficient accuracy and precision to map chemical bonds in and around nanostructures in nanostructured materials. This has never before been possible as experimental measurements of bonding in quantum crystallography have hitherto always been restricted to homogeneous single-phased crystals.

Social media has become the most influential battleground for political and societal debate. The reach, the speed, and the fact that everybody can participate make this medium very popular but also highly manipulative, subject to biases and extremely precious to control. Misinformation spreads in an unforeseeable way. Sometimes it just follows usual non-malicious social interaction patterns, but often a targeted and designed-for-purpose manner. In this paper, we propose a novel method to identify the most effective opportunities to moderate the social media debate at a large scale using the properties of social signed graphs, such as structural balance. After building the topic universe for a particular political debate in a given time frame, we extract the most active and influential users and mine their position regarding the topic based on their interactions with other users. The result is a signed graph where each edge represents either support or challenge between a pair of users in the context of the topic. This graph can be modelled as an Ising model, with the goal of minimizing its energy state by using the advantages of Adiabatic Quantum Computing. Applying this principle, we use a Quantum Annealing implementation to solve the problem of finding the edges violating the structural balance of this graph, which in classic computing is known to be an NP-hard problem. We then provide a non-intrusive moderation technique for those violations to mitigate or increase the structural imbalance, depending on the desired strategy. The methodology is shown in the context of the COVID-19 skeptics’ debate in Twitter and implemented using a D-Wave 2000Q-6 quantum annealer.

The interpretation of published experimental results intended to prove the existence of a quantum phenomenon of non-locality involving photonic entangled states did not take into consideration the existence of the quantum Rayleigh conversion of photons in dielectric media. This phenomenon leads to the existence of high levels of correlations between two independent photonic and linearly polarized quantum states generated after the entangled photons have been absorbed through the quantum Rayleigh conversion. Both pure and mixed individual states of polarization result in expressions normally associated with entangled photonic states, providing support for the view that the physical reality of quantum non-locality is highly questionable.

I examine the groups which underly classical mechanics, non-relativistic quantum mechanics, special relativity, relativistic quantum mechanics, quantum electrodynamics, quantum flavourdynamics, quantum chromodynamics, and general relativity. This examination includes the rotations SO(2) and SO(3), the Pauli algebra, the Lorentz transformations, the Dirac algebra, and the U(1), SU(2), and SU(3) gauge transformations. I argue that general relativity must be generalized to Einstein-Cartan theory, so that Dirac spinors can be described within the framework of gravitation theory.

In quantum many-body systems, a Hamiltonian is called an ``extensive entropy generator'' if starting from a random product state the entanglement entropy obeys a volume law at long times with overwhelming probability. We prove that (i) any Hamiltonian whose spectrum has non-degenerate gaps is an extensive entropy generator; (ii) in the space of (geometrically) local Hamiltonians, the non-degenerate gap condition is satisfied almost everywhere. Specializing to many-body localized systems, these results imply the observation stated in the title of Bardarson et al. [PRL 109, 017202 (2012)].

The classical uncertainty principle inequalities were imposed as a mathematical constraint over the general relativity geodesic equation. In this way, the uncertainty principle was reformulated in terms of the proper space-time length element, Planck length and a geodesic-derived scalar, leading to a geometric expression for the uncertainty principle (GeUP). This re-formulation confirmed the necessity for a minimum length for the space-time line element in the geodesic, dependent on a geodesic-derived scalar which made the expression Lorentz-covariant. In agreement with quantum gravity theories, GeUP required the imposition of a perturbation over the background Minkowski metric unrelated to classical gravity. When applied to the Schwarzschild metric, a geodesic exclusion zone was found around the singularity where uncertainty in space-time diverged to infinity.

This conceptual, interdisciplinary paper will start by introducing the commencement of a new era in which human society faces continuously accelerating technological revolutions, named for short ‘Padkos’. In this context, a conceptual model of sustainable development with a focus on knowledge sharing and management will be proposed. The construct of knowledge management will be unpacked into a three-layer model with a focus on the knowledge-human and data-machine spheres. Then, each sphere will be discussed with concentrating on the learning and decision- making processes, the digital supporting systems and the human actors’ aspects. Moreover, the recombination of new knowledge development and contemporary knowledge management into one amalgamated construct will be proposed. The holistic conceptual model of knowledge sharing for sustainable development is comprised by time, cybersecurity and two alternative humanistic paradigms (Homo Technologicus and Homo Sustainabiliticus). Two additional particular models are discussed in depth. First, a recently proposed model of quantum organizational decision-making is elaborated. Next, a boundary management and learning process is particularized. The paper ends with several implications for the future based on the deliberations in the paper and the models discussed.

In the present work, a superlattice structure comprising superconducting and insulator layers is studied. Here, if a magnetic field is applied parallel to the layers, the lack of a pinning center leads to a novel transition; in particular, as the applied magnetic field is reduced, the stationary wave surrounding the magnetic flux quantum in the superconducting layer eventually collides with the superconducting–insulating interfaces on both sides because its radius becomes larger than the width of the superconducting layer. At this instant, the stationary wave will collapse, and a transition will occur: the magnetic quanta are collapsed and thus the uniform magnetic field distribution is achieved, which corresponds to the transition from the superconducting state to the normal state over critical current. Considering a one-dimensional model of the structure, a critical current density equation is derived that indicates an increase in the critical current density for increased applied magnetic field. Subsequently, the same calculation was conducted after changing the direction of the magnetic field component, and the combination of these two calculations expresses the anisotropic property of the structure. The phenomenon is also predicted for anisotropic critical current density. This phenomenon is an important discovery that helps manufacture high-temperature superconducting tape as well as large high-temperature superconducting coils.

There is growing recognition in research and policy of a mental health crisis among Canada’s paramedics but despite this, epidemiological surveillance of the problem is in its infancy. Just weeks before the emergence of the COVID-19 pandemic, we surveyed paramedics from a single, large, urban paramedic service in Ontario, Canada to assess for symptom clusters consistent with Post-Traumatic Stress Disorder (PTSD), major depressive disorder, and generalized anxiety disorder and to identify potential risk factors for each. In total, we received 589 completed surveys (a 97% completion rate) and found that 11% screened positive for PTSD, 15% for depression, and 15% for anxiety, with 1 in 4 active-duty paramedics screening positive for any of the three as recently as February 2020. In adjusted analyses, the risk of a positive screen varied as a function of employment classification, gender, self-reported resilience, and previous experience as a member of the service’s peer support team. Our findings support the position that paramedics screen positive for mental disorders at high rates – a problem likely to have worsened since the onset of the COVID-19 pandemic. We echo the calls of researchers and policymakers for urgent action to support paramedic mental health in Canada.

Density distribution function of classical statistical mechanics is generally generalized as a product of a general complex function and its complex Hermitian conjugate function, and the average of classical statistical mechanics is generalized as the average of the quantum mechanics. Furthermore, this paper derives three ones of the five axiom presumptions of quantum mechanics, e.g., deduces Schrȍdinger equation by two general ways, makes the three axiom presumptions into three theorems of quantum mechanics, not only solves the crisis to hard understand, but also gets new theories and new discoveries, e.g., this paper solves the crisis of the origin of the wave-particle duality, derives operators, eigenvalues and eigenstates, deduces commutation relations for coordinate and momentum as well as the time and energy, and discovers quantum mechanics is just a generalization ( mechanics ) theory of the complex square root of ( real density function of ) classical statistical mechanics. Quantum mechanics being just a generalization theory of the complex square root of classical statistical mechanics is both new physics and revolutionary discovery, which are affecting people’s deep philosophical thinking for modern physics development, solve all the crisises of quantum mechanics, quantum information and so on, and make quantum mechanics have scientific solid bases being checked and both no basic axiom presumption and no all the quantum strange incomprehensible properties, because classical statistical mechanics and the complex square root of classical statistical mechanics have the scientific solid bases being checked. In addition, this paper discovers the reason no taking the time derivative of space coordinates in Schrȍdinger equation. Therefore, this paper gives solution to the crisis of the first quantization origin, and mainly deduces quantum physics no all the quantum current strange incomprehensible properties.

proposal for a fundamental theory is described in which classical and quantum physics as a representation of the universe as a gigantic dendrogram are unified. The latter is the explicate order structure corresponding to the purely number-theoretical implicate order structure given by p-adic numbers. This number field was zero-dimensional, totally disconnected, and disordered. Physical systems (such as electrons, photons) are sub-dendrograms of the universal dendrogram. Measurement process is described as interactions among dendrograms; in particular, quantum measurement problems can be resolved using this process. The theory is realistic, but realism is expressed via the the Leibnitz principle of the Identity of Indiscernible. The classical-quantum interplay is based on the degree of indistinguishability between dendrograms (in which the ergodicity assumption is removed). Depending on this degree, some physical quantities behave more or less in a quantum manner (versus classic manner). Ideologically, our theory is very close to Smolin’s dynamics of difference and Rovelli’s relational quantum mechanics. The presence of classical behavior in nature implies a finiteness of the Universe-dendrogram. (Infinite Universe is considered to be purely quantum.) Reconstruction of events in a four-dimensional space type is based on the holographic principle. Our model reproduces Bell-type correlations in the dendrogramic framework. By adjusting dendrogram complexity, violation of the Bell inequality can be made larger or smaller.

Manual visual inspections typically conducted after an earthquake are high-risk, subjective, and time-consuming. Delays from inspections often exacerbate the social and economic impact of the disaster on affected communities. Rapid and autonomous inspection using images acquired from unmanned aerial vehicles offer the potential to reduce such delays. Indeed, a vast amount of re-search has been conducted toward developing automated vision-based methods to assess the health of infrastructure at the component and structure level. Most proposed methods typically rely on images of the damaged structure, but seldom consider how the images were acquired. To achieve autonomous inspections, methods must be evaluated in a comprehensive end-to-end manner, incorporating both data acquisition and data processing. In this paper, we leverage recent advances in computer generated imagery (CGI) to construct a 3D synthetic environment for simulation of post-earthquake inspections that allows for comprehensive evaluation and valida-tion of autonomous inspection strategies. A critical issue is how to simulate and subsequently render the damage in the structure after an earthquake. To this end, a high-fidelity nonlinear finite element model is incorporated in the synthetic environment to provide a representation of earthquake-induced damage; this finite element model, combined with photo-realistic rendering of the damage, is termed herein a physics-based graphics models (PBGM). The 3D synthetic en-vironment with PBGMs provide a comprehensive end-to-end approach for development and validation of autonomous post-earthquake strategies using UAVs, including: (i) simulation of path planning of virtual UAVs and image capture under different environmental conditions; (ii) au-tomatic labeling of captured images, potentially providing an infinite amount of data for training deep neural networks; (iii) availability of the ground truth damage state from the results of the finite-element simulation; and (iv) direct comparison of different approaches to autonomous as-sessments. Moreover, the synthetic data generated has the potential to be used to augment field datasets. To demonstrate the efficacy of PBGMs, models of reinforced concrete moment-frame buildings with masonry infill walls are examined. The 3D synthetic environment employing PBGMs is shown to provide an effective testbed for development and validation of autonomous vision-based post-earthquake inspections that can serve as an important building block for ad-vancing autonomous data to decision frameworks.

It is proposed to incorporate the concepts of brain microbiota and microbial consciousness in the Orchestrated Objective Reduction (Orch OR) theory of human consciousness with the goal of increasing its explanatory and predictive powers. If consciousness arises from quantum computations in cytoskeletal structures inside human neurons, there is no theoretical impediment at hypothesizing that it might also occur in the cytoskeletal structures of the microbes resident in the human brains. If the concept of the brain microbiota is integrated in a general Orch OR theory, its explanatory and predictive powers would be vastly increased.

We present the mathematical model of cooperative functioning of unconscious and consciousness. The model is based on the theory of open quantum systems. Unconscious and consciousness are treated as bio-information systems. The latter plays the role a measurement apparatus for the former. States of both systems are represented in Hilbert spaces. Consciousness performs measurements on the states which are generated in unconscious. This process of unconscious-conscious interaction is described by the scheme of indirect measurements. This scheme is widely used in quantum information theory and it leads to the theory of quantum instruments (Davis-Lewis-Ozawa). Our approach is known as quantum-like modeling. It should be sharply distinguished from modeling of genuine quantum physical processes in biosystems, in particular, in the brain. In the quantum-like framework, the brain is a black box processing information in the accordance with the laws of quantum theory. During the last 10-15 years this framework has been actively used in cognition, psychology, decision making, social and political sciences. The quantum-like scheme of unconscious-consciousness functioning has already been explored for sensation-perception modeling.

One of the biggest queries in cognitive sciences is the emergence of consciousness from matter. Modern neurobiological theories of consciousness propose that conscious experience is the result of interactions between large-scale neuronal networks in the brain, traditionally described within the realm of classical physics. Here, we propose a generalized connectionist framework in which the emergence of “conscious networks” is not exclusive of large brain areas, but can be identified in sub-cellular networks exhibiting non-trivial quantum phenomena. The essential feature of such networks is the existence of strong correlations in the system (classical or quantum coherence) and the presence of an optimal point at which the system’s complexity is maximized, expressed either by maximization of the information content in large scale functional networks or by achieving optimal efficiency through the quantum Goldilock effect.

Smoking during pregnancy remains one of the most significant risk factors for poor birth outcomes. The Loma Linda University Health Comprehensive Tobacco Treatment Program (CTTP) is the largest maternal tobacco cessation program in San Bernardino County – the largest county in the contiguous US. CTTP is an eight week, incentivized, behavioral intervention for tobacco cessation for pregnant smokers. As part of program evaluation, we used a retrospective cohort design to assess smoking abstinence and to identify predictors of relapse/smoking after enrollment. Among CTTP cohort enrollees (n=233) from 2012-2013 we found: 1) a 28.4% 8 week point prevalence abstinence (PPA), and at a median of 9 months of follow-up after the PPA, 81.6% continued to indicate tobacco cessation, and 2) a high rate of relapse or loss to follow-up (56%). Our modeling of relapse/smoking after enrollment indicated that this was higher in young mothers, non-Hispanic mothers (White, Black), first/third trimester mothers, and rural mothers. The evaluation identified efficacy of the behavioral model at 8 weeks, but that relapse/smoking was occurring in disparity populations. Formative research is needed to expand the programmatic outreach and enrollment of mothers wanting to quit smoking.

The efficiency of data sorting algorithms is the key aspect which determines the speed of data processing and searching. The best known efficiency of sorting algorithm has been Log (N) if there are N terms. All of the well-known sorting algorithms use various techniques to sort data. The basis for most of these are comparing the data terms with each other. In this manuscript, we are introducing a new approach for sorting data. This method is postulated to have the highest efficiency ever achieved by any of the sorting algorithms. We achieve this by sorting data without comparing the data terms. Or achieving results of data comparison without comparing the terms explicitly.

Whether the universe is a computer simulation, or whether we wish to efficiently model our universe in a computer simulation, there would be benefits to modeling it in a fashion analogous to computer spreadsheet, each lattice cell can be conceived as containing all the mathematical formula necessary to continuously compute its state relative to changes in all its neighboring cells, and by progression, in relation to all the cells of entire space-time lattice. Alternatively, the “real” universe may itself be built on a space cell lattice, an irregular foam of space cells, in which each cell may be conceived as a multidimensional cell of distortable space, the shape of which fully describes (a) the four basic forces (gravity, electromagnetic, strong, weak) observed at that cell of space, and (b) the probability (or weight distribution) of any quantum states overlapping the cell and its neighbors. At an appropriate scale, it would appear that this conceptual model would resolve apparent conflicts between general relativity and quantum physics. It would also provide a new interpretation of Planck’s constant as description of the number of space cell events associated with any set of observable events. If formulae operating at a lattice cell level can be improve our ability to understand and model larger scale phenomena, this would be strong evidence in favor of the theory that mathematics is not just a human invention but rather an inherent feature of space-time itself.

Role identity theory describes the purpose and meaning in life that comes, in part, from occupying social roles. While robustly linked to health and well-being, this may become, however, when an individual is unable to fulfil the perceived requirements of an especially salient role in the way that they believe they should. Amid high rates of mental illness among public safety personnel, we interviewed a purposely selected sample of 21 paramedics from a single service in Ontario, Canada to explore incongruence between an espoused and able-to-enact paramedic role identity. Situated in an interpretivist epistemology, and using successive rounds of thematic analysis, we developed a framework for role identity dissonance wherein chronic, identity-relevant disruptive events cause emotional and psychological distress. While some participants were able to recalibrate their sense of self and understanding of the role, for others, this dissonance was irreconcilable, contributing to disability and lost time from work. In addition to contributing a novel perspective on paramedic mental health and well-being, our work also offers a modest contribution to the theory in using the paramedic context as an example to consider identity disruption through chronic workplace stress.

We investigate molecular beam epitaxy growth conditions of micrometers-thick In0.52Al0.48As designed for waveguide of InGaAs/InAlAs/InP quantum cascade lasers. Effect of growth temperature and V/III ratio on the surface morphology and defect structure were studied. The growth conditions which were developed for the growth of cascaded In0.53Ga0.47As/In0.52Al0.48As active region, e.g. growth temperature of TG=520°C and V/III ratio of 12, turned out to be not optimum for the growth of thick In0.52Al0.48As waveguide layers. It has been observed that after exceeding ~1µm thickness the quality of In0.52Al0.48As layers deteriorates. The in-situ optical reflectometry showed increasing surface roughness caused by defect forming, which was further confirmed by High Resolution X-Ray reciprocal space mapping, optical microscopy and atomic force microscopy. The presented optimization of growth conditions of In0.52Al0.48As waveguide layer led to the growth of defect free material, with good optical quality. This has been achieved by decreasing the growth temperature to TG=480 °C with appropriate increasing V/III ratio. At the same time the growth conditions of the cascade active region of the laser were left unchanged. The lasers grown using new recipe have shown lower threshold currents and improved slope efficiency. We relate this performance improvement to reduction of the electron scattering on the interface roughness and decreased waveguide absorption losses.

In quantum field theory (QFT), it is well known that when Feynman diagrams containing loops are evaluated to account for self interactions, probability amplitude comes out to be infinite which is physically not admissible. So, to make the QFT convergent, various renormalization methods are conventionally followed in which an additional (infinite) counter term is postulated which neutralizes the original infinity generated by diagram. The resulting finite values of amplitudes have agreed with experiments with surprising accuracy. However, proponents of renormalization methods acknowledged that this ad-hoc procedure of subtraction of infinity from infinity to reach at a finite value is not at all satisfactory and there is no physical basis for bringing in the counter term. So, it is desirable to establish a method in QFT which does not generate any infinite term (thus not requiring renormalization), but which predicts same results as conventional methods do. In this paper, we describe such a technique taking self interaction quantum electrodynamics diagram representing electron or photon self energy. In our method, no problem of infinity arises and hence renormalization is not necessary. Still, the dependence of calculated probability amplitude on physical variables in our technique comes out to be same as conventional methods. Using similar procedure, we hope, the problem of non-renormalizability of quantum gravity may be solved in future.

This study presents the B92 Quantum Key Distribution scheme and its optimization and implementation considerations. Simulation software was developed to model and analyze the B92 protocol under varying conditions. Another contribution of this work is investigating how this protocol runs on real quantum computing hardware. New eavesdropping schemes were proposed and modeled.

Plastid gene expression involves many post-transcriptional maturation steps resulting in a complex transcriptome composed of multiple isoforms. Although short read RNA-seq has considerably improved our understanding of the molecular mechanisms controlling these processes, it is unable to sequence full-length transcripts. This information is however crucial when it comes to understand the interplay between the various steps of plastid gene expression. Here, the study of the Arabidopsis leaf plastid transcriptome using Nanopore sequencing showed that many splicing and editing events were not independent but co-occurring. For a given transcript, maturation events also appeared to be chronologically ordered with splicing happening after most sites are edited.

The fact that quantum gravity does not admit a co-variant vacuum state has far-reaching consequences for all physics. It points out that space could not be empty, and we return to the notion of an ether . Such a concept requires a preferred reference frame for, e.g., universe expansion and black holes. Here, we intend to discuss vacuum and quantum gravity from three essential viewpoints: universe expansion, black holes existence, and quantum decoherence.

The interaction between single or a fixed number of photons with a single absorber is of fundamental interest in quantum technology. The harnessing of light matter interactions at the single particle limit has several potential applications ranging from quantum communication and quantum metrology to quantum imaging. In this letter, a setup for heralded two-photon absorption at the single absorber level is proposed. The setup is based on a heralded two-photon source utilizing spontaneous parametric down-conversion, entanglement swapping and sum frequency generation for joint detection. The feasibility of the scheme is discussed by reviewing recent achievements in utilizing entangled and correlated photons for two-photon absorption as well as single photon absorption experiments at the limit of single absorbers in the context of applications in imaging (here mainly microscopy) and spectroscopy.

Aggregated alpha-synuclein (-synuclein) is the main component of Lewy bodies (LBs), Lewy neurites (LNs), and glial cytoplasmic inclusions (GCIs), which are pathological hallmarks of idiopathic Parkinson’s disease (IPD) and multiple system atrophy (MSA), respectively. Initiating factors that culminate in forming LBs/LNs/GCIs remain elusive. Several species of -synuclein exist, including phosphorylated and nitrated forms. It is unclear which -synuclein post-translational modifications (PTMs) appear within aggregates throughout disease pathology. Herein we aimed to establish the predominant synuclein PTMs in post-mortem IPD and MSA pathology using immunohistochemistry. We examined the patterns of three -synuclein PTMs (pS87, pS129, nY39) simultaneously in pathology-affected regions of 15 PD, 5 MSA, 6 neurologically normal controls. All antibodies recognized LBs, LNs, and GCIs, albeit to a variable extent. pS129 -synuclein antibody was particularly immunopositive for LNs and synaptic dot-like structures followed by nY39 -synuclein antibody. GCIs, neuronal inclusions, and small threads were positive for nY39 -synuclein in MSA. Quantification of the LB scores revealed that pS129 -synuclein was the dominant and earliest -synuclein PTM followed by nY39 -synuclein, while lower amounts of pSer87 -synuclein appeared later in disease progression in PD. These results may have implications for novel biomarker and therapeutic developments.

We generalize the idea of quantum clock time to quantum spacetime reference frame via physical realization of a reference system by quantum rulers and clocks. Omitting the internal degrees of freedom (such as spins) of the physical rulers and clocks, only considering their metric properties, the spacetime reference frame is described by a bosonic non-linear sigma model (NLSM). We study the quantum behavior of the system under approximations, and obtain (1) a cosmological constant valued (2/π)ρ_c0 (ρ_c0 the critical density at near current epoch) which is very close to the observations; (2) an effective Einstein-Hilbert term; (3) the ratio of variance to mean-squared of spacetime interval tends to a universal constant 2/π in the infrared region. This effect is testable by observing a linear dependence between the inherent quantum variance and mean-squared of the redshifts from cosmic distant spectral lines. The proportionality is expected to be the observed percentage of the dark energy. The equivalence principle is also generalized to the quantum level.

The effectiveness of forest resources depends on the comprehensiveness and rationality of their consumption and processing into finished products. This article discusses a problem of utilising solid fir wood greenery residues generated during the industrial production of essential oils. Bioconversion is considered to be the most promising utilization method. The objective of this research was to study the chemical composition of bioconversion products of fir wood greenery-based substrates. The РР-3.2 strain of Pleurotus pulmonarius (Fr.) Quél was used as a biodestructor. In the process of bioconversion, the contents of polysaccharides and lignin substances is reduced to 38 and 28 % respectively. Up to 20 % of protein accumulates in bioconversion products of fir wood greenery. The amount of nucleic acids is not more than 1.5 g per 1 kg, the contents of heavy metals, such as mercury, cadmium, arsenic, lead, do not exceed maximum permissible concentration standards. The substrate weight loss reaches 15 %. When fallen leaves and post-extraction poplar bud residues are added to the substrate, the substrate-destroying activity of fungi rises, as well as the protein content increases by 3 %. The digestibility of products as a result of bioconversion increases 1.6–2.8 times depending on the substrate composition. The obtained data enable to recommend post-fermented substrates based on fir wood greenery and balsam poplar biomass for use as a protein feed additive.

The interaction of electrons with strong laser fields is usually treated with semiclassical theory, where the laser is represented by an external field. There are analytic solutions for the free electron wave functions, which incorporate the interaction with the laser field exactly, but the joint effect of the atomic binding potential presents an obstacle for the analysis. Moreover, the radiation is a dynamical system, the number of photons changes during the interactions. Thus, it is legitimate to ask how can one treat the high order processes nonperturbatively, in such a way that the electron-atom interaction and the quantized nature of radiation be simultaneously taken into account? An analytic method is proposed to answer this question in the framework of nonrelativistic quantum electrodynamics. As an application, a quantum optical generalization of the strong-field Kramers-Heisenberg formula is derived for describing high-harmonic generation. Our formalism is suitable to analyse, among various quantal effects, the possible role of arbitrary photon statistics of the incoming field. The present paper is dedicated to the memory of Prof. Dr. Fritz Ehlotzky, who had significantly contributed to the theory of strong-field phenomena over many decades.

Facing unprecedented global declines in the extent and integrity of ecosystems, the 15^th UN Biodiversity Conference (COP-15) in Kunming, China, presents an opportunity for transformative change. However, a lack of consensus on two key issues – resource mobilization and Access and Benefit Sharing (ABS) associated with Digital Sequence Information (DSI) – risks stalling negotiations for an ambitious ‘Post-2020 Global Biodiversity Framework’ as the next 10-year strategic plan under the Convention on Biological Diversity. We highlight systemic misconceptions concerning the financing of biodiversity and the burden this places on the ABS system. In the context of DSI, we caution that conflating ABS with resource mobilization risks disrupting modern science policy built on open access, with potentially severe ramifications for scientific research and innovation. To resolve these tensions, we call for a recalibration of discussions on ABS in order to maximize the value delivered by biodiversity for all of society, including indigenous peoples and local communities.

We present a thermodynamic approach in modeling the evolution of the universe based on a theory that space consists of energy quanta, the spaceons. From wave-particle duality, they can be treated as an ideal gas. The model is similar to the Big Bang but without Inflation. It provides an insight into the nature of dark energy and dark matter, and an explanation for the accelerated expansion of the universe. The universe started from an atomic size volume of spaceons at very high temperature and pressure. Upon expansion and cooling, phase transitions occurred resulting in the formation of fundamental particles, and matter. These nucleate and grow into stars, galaxies, and clusters due to the action of gravity. From the cooling curve of the universe we constructed a thermodynamic phase diagram of cosmic composition, from which we obtained the correlation between dark energy and the energy of space. Using Friedmann’s equations, our model fits well the WMAP data on cosmic composition with an equation of state parameter, w= -0.7. The dominance of dark energy started at 7.25 x 10⁹ years, in good agreement with BOSS measurements. The expansion of space is attributed to a scalar quantum space field. Dark Matter is identified as a plasma form of matter similar to that which existed during the photon epoch, prior to recombination. The thermodynamics of expansion of the universe was adiabatic and decelerating during the first 7 billion years after the Big Bang; it accelerated thereafter. A negative pressure for Dark Energy is required to sustain the latter. This is consistent with the theory of General Relativity and the law of conservation of energy. We propose a mechanism for the acceleration as due to consolidation of matter forming Dark Energy Stars (DES) and other compact objects. The resulting reduction in gravitational potential energy feeds back energy for the expansion. Space will continue to expand and dark energy will undergo phase transition to a Bose-Einstein condensate, a superfluid form of matter. Self-gravitation can cause a bounce and start a new Big Bang. We show how the interplay of gravitational and space forces leads to a cyclic, maybe eternal, universe.

We propose a novel interpretation of consciousness and an enlarged definition of locality, which provide a solution to the problem of the consistency of measurements in quantum mechanics: consciousness is a characteristics of the Universe as a whole. Besides its physical conse- quences, this interpretation has also moral implications: individuality comes out naturally to be just an accident functional to evolution which shaped past and present history through competition, and re- alizing this fact should enforce cooperation.

At present there is a renewed interest in theories of ”modified” gravity. Here, under a more drastic modification enforced by Galilei group, we obtain a completely new gravitational structure, and which exists in addition to the already available general relativity of today. Correlated with this, we show that in addition, there is a new ”modified” quantum mechanics, in as much as it exists as an independent and new ”pure” non-relativistic quantum me- chanics, and which has no relativistic counterpart. This is in addition to the present quantum mechanics, where the relativistic and non-relativistic structures are counterparts of each other. The above holds, firstly due to the correlation between Galilei group and quantum mechanics. These math- ematical conclusions are consolidated by the fact that there exists a physical Majorana interaction between each neutron- proton pairs in nuclei. Galilei invariance of Majorana exchange in Majorana interaction, shows that the mass here is of pure gravitational nature, and which is immune to the other three forces. This makes an amazing connection between the gravitational force and the quantum mechanics. This pure gravitational mass would man- ifest itself as dark matter of the universe. It is our new modified gravity that generates the dark matter.

In this study an adjusting post-processing approach is implemented for improving intra-hourly forecasts of solar power and ramp events of PV solar power systems at different locations in the United States. This study also serves as an out-of-sample test to evaluate the performance of the adjusting approach with different locations and timescales. Thus, various individual intra-hourly forecasts of solar power are combined and adjusted by applying the adjusting approach. Both point and probabilistic forecasts of solar power are included. After that, solar power ramp event forecasting by the adjusting approach is carried out.

In this article we presented an application of the quantum cosmological model in teleparallel gravity. Working with a vacuum solution, the gravitational energy density is quantized with the Weyl procedure and we obtain a discrete expression for the gravitational energy. As an immediate consequence the empty space exhibits an expansion for an early universe.

The tryptophan (TRP)-kynurenine (KYN) metabolic pathway is a main player of TRP metabolism through which more than 95% of TRP is catabolized. The pathway is activated by acute and chronic immune responses leading to a wide range of illnesses including cancer, immune diseases, neurodegenerative diseases, and psychiatric disorders. The TRP-KYN pathway synthesizes multifarious metabolites including oxidants, antioxidants, neurotoxins, neuroprotectants, and immunomodulators. The immunomodulators are known to facilitate the immune system towards a tolerogenic state, resulting in chronic low-grade inflammation (LGI) that is commonly present in obesity, poor nutrition, exposer to chemicals or allergens, prodromal stage of various illnesses, and chronic diseases. KYN, kynurenic acid, xanthurenic acid, and cinnabarinic acid are aryl hydrocarbon receptor ligands that serve as immunomodulators. Furthermore, TRP-KYN pathway enzymes are known to be activated by the stress hormone cortisol and inflammatory cytokines, and genotypic variants were observed to contribute to inflammation and thus various diseases. The tryptophan 2,3-dioxygenase, the indoleamine 2, 3-oxygenases, and the kynurenine-3-monooxygenase are main enzymes in the pathway. This review article discusses the TRP-KYN pathway with special emphasis on its interaction with the immune system and the tolerogenic shift towards chronic LGI and overviews the major symptoms, pro- and anti-inflammatory cytokines, and toxic and protective KYNs to explore the linkage between chronic LGI, KYNs, and major psychiatric, including depressive disorder, bipolar disorder, substance use disorder, post-traumatic stress disorder, schizophrenia, and autism spectrum disorder.

Considering the predictions from the standard model of particle physics coupled with experimental results from particle accelerators, we discuss a scenario in which from the infinite possibilities in the Lie groups we use to describe particle physics, nature needs only the lower dimensional representations - an important phenomenology that we argue indicates nature is code theoretic. We show that the quantum deformation of the SU(2) Lie algebra at the fifth root of unity can be used to address the quantum Lorentz group representation theory through its universal covering group and gives the right low dimensional physical realistic spin quantum numbers confirmed by experiments. In this manner we can describe the spacetime symmetry content of relativistic quantum fields in accordance with the well known Wigner classification. Further connections of the fifth root of unity quantization with the mass quantum number associated with the Poincaré Group and the SU(N) charge quantum numbers are discussed as well as their implication for quantum gravity.

This paper results from our investigation into novel means of electromagnetic propulsion. It requires the basis of our claims to be put on a sound theoretical footing regarding the purported momentum exchange with the electromagnetic field. One of these concerns is the huge discrepancy between the energy density of the Zeropoint and its purported manifestation as the Cosmological Constant. Here we state that it is manifestly wrong to introduce the zeropoint at zero order into the stress-energy tensor, because it is something which describes zero particle count. As a fluctuation, it belongs in a higher order Taylor expansion in frequency of the stress-energy tensor. Furthermore in the 3^rd order in the Einstein constant our procedure is some 9 orders of magnitude too small. We make up this difference by suggesting that vacuum energy is much higher still and that more degrees of freedom exist in physics beyond the Standard Model or that there is interaction energy between the modes.

Planck's constant plays an important role in quantum mechanics but has little physical meaning apart from its contribution to the formulas. Evaluating each of the constant's unit dimensions gives a more granular account of the physical phenomena described by the equations. These formulas show how classical and quantum mechanical equations are related, and they give consistent descriptions of phenomena like momentum and energy in classical and quantum systems.

The paper presents new data on mineralogical-geochemical peculiarities of the granites and pegmatites of the Baikal area (Olkhon Region) with implications for the age, generation conditions and geodynamic settings of magmatism. The early Paleozoic granitoids of the Olkhon region are syncollisional formations produced from the gneiss-schistose substratum of the Olkhon metamorphic sequences. Pegmatoid granites and pegmatites of the Region were generated within a wide age range (458-390 Ma) and include different mineralogical and geochemical types. Amongst the Early Paleozoic granitoids, pegmatoid rocks are products of the collisional magmatism evolution and are similar to granites in terms of the mineral composition and distribution patterns of rare and rare earth elements. On the Olkhon island (Baikal lake) the pegmatite of the Tashkiney vein belong to the Be-Nb-Ta mineralogical-geochemical type demonstrating high contents of W, Sn U, Th and very low concentrations of Li and volatile components (F, B). In the Pryolkhonye area, vein pegmatite Iliksin is with Li, Be, Nb, Ta mineralization (lepidolite, vorobyevite, samarskite et al). The studied pegmatite veins are similar both by the profound negative Ba, Sr, Eu, and Zr anomalies. The zircons from the Tashkiney vein (390±5.0 Ma) and of the Iliksin vein (430.1±2.2 Ma, U-Pb isotope LA ICP MS metod) indicate the formation of pegmatite at the late post-collisional stage of magmatism in the Olkhon Region. As regard to mineralogical and geochemical characteristics, vein pegmatites with amazonite (Ainsky and Ulan-Nur) belong to the Li-F type. The tantalum mineralization, represented by microlites and minerals of the columbite-tantalite group is associated with the Ainsky amazonite pegmatite. As opposed to the Early Paleozoic syncollisional granitoids and pegmatoid formations, the middle Paleozoic vein bodies of pegmatites (Tashkiney, Iliksin, Ainsky, Ulan-Nur) are regarded as rare-metal pegmatites. In terms of geochemical characteristics, they are similar to the rare-metal pegmatoid granites and pegmatites of the intra-plate setting widespread in Mongolia and Transbaikalia. The rare-metal mineralization in the Olkhon region may be genetically related to the evolution of Be-Nb-Ta and Li-F types of the post-collisional granites and pegmatites.

ME/CFS (Myalgic Encephalomyelitis / Chronic Fatigue Syndrome) is a chronic, complex, heterogeneous disease that affects millions and lacks both diagnostics and treatments. Big data, or the collection of vast quantities of data that can be mined for information, has transformed the understanding of many complex illnesses like cancer (1,2) and multiple sclerosis (3,4), by dissecting heterogeneity, identifying subtypes, and enabling the development of personalized treatments. It is possible that big data can reveal the same for ME/CFS. Solve M.E. developed and launched the You + ME Registry to collect longitudinal health data from people with ME/CFS, people with Long COVID (LC) and control volunteers using rigorous protocols designed to harmonize with other groups collecting data from similar groups of people. The Registry is an invaluable resource because it integrates with a symptom tracking app, as well as a biorepository, to provide a robust and rich dataset that is available to qualified researchers. Accordingly, it facilitates collaboration that may ultimately uncover causes and help accelerate the development of therapies.

We study the performance of a classical and quantum magnetic Otto cycle with a quantum dot as a working substance using the Fock-Darwin model with the inclusion of the Zeeman interaction. Modulating an external/perpendicular magnetic field, we found in the classical approach an oscillating behavior in the total work that is not perceptible under the quantum formulation. Also, we compare the work and efficiency of this system for different regions of the Entropy, $S(T,B)$, diagram where we found that the quantum version of this engine always shows a reduced performance in comparison to his classical counterpart.

An interesting anomaly of the diffusion process with an apparently negative diffusion coefficient defined through the mean-square displacement in a one-dimensional quantum molecular chain model is shown. Nevertheless, the system satisfies the H-theorem, so that the second law of thermodynamics is satisfied. The reason why the “diffusion constant” becomes negative is due to the effect of the phase mixing process, which is a characteristic result of the one-dimensionality of the system. We illustrate the situation where this negative “diffusion constant” appears.

The aim of this review is to provide a survey of the recent advances and the main remaining challenges related to the ultrananocrystalline diamond (UNCD) nanowires and other nanostructures which exhibit excellent capability as the core components for many diverse novel sensing devices, due to the unique material properties and geometry advantages. The doping introduced in the gas phase during deposition promotes p-type or n-type conductivity. With the establishment of the UNCD nanofabrication techniques, more and more nanostructure based devices are being explored in measuring basic physical and chemical parameters via classic and quantum methods, as exemplified by gas sensors, ultraviolet photodetectors, piezoresistance effect based devices, biological applications, and nitrogen-vacancy color center based magnetic field quantum sensors. Highlighted finally are some of the remaining challenges and future outlook in this area.

The paper discusses the 2022 Nobel Prize in physics for experiments of entanglement “establishing the violation of Bell inequalities and pioneering quantum information science” in a much wider, including philosophical context legitimizing by the authority of the Nobel Prize a new scientific area out of “classical” quantum mechanics relevant to Pauli’s “particle” paradigm of energy conservation and thus to the Standard model obeying it. One justifies the eventual future theory of quantum gravitation as belonging to the newly established quantum information science. Entanglement, involving non-Hermitian operators for its rigorous description, non-unitarity as well as nonlocal and superluminal physical signals “spookily” (by Einstein’s flowery epithet) synchronizing and transferring some nonzero action at a distance, can be considered to be quantum gravity so that its local counterpart to be Einstein’s gravitation according to general relativity therefore pioneering an alternative pathway to quantum gravitation different from the “secondary quantization” of the Standard model. So, the experiments of entanglement once they have been awarded by the Nobel Prize launch particularly the relevant theory of quantum gravitation grounded on “quantum information science” thus granted to be nonclassical quantum mechanics in the shared framework of the generalized quantum mechanics obeying rather quantum-information conservation than only energy conservation. The concept of “dark phase” of the universe naturally linked to the very well confirmed “dark matter” and “dark energy” and opposed to its “light phase” inherent to classical quantum mechanics and the Standard model obeys quantum-information conservation, after which reversible causality or the mutual transformation of energy and information are valid. The mythical Big Bang after which energy conservation holds universally is to be replaced by an omnipresent and omnitemporal medium of decoherence of the dark and nonlocal phase into the light and local phase. The former is only an integral image of the latter and borrowed in fact rather from religion than from science. Physical, methodological and proper philosophical conclusions follow from that paradigm shift heralded by the 2022 Nobel Prize in physics. For example, the scientific theory of thinking should originate from the dark phase of the universe, as well: probably only approximately modeled by neural networks physically belonging to the light phase thoroughly. A few crucial philosophical sequences follow from the break of Pauli’s paradigm: (1) the establishment of the “dark” phase of the universe as opposed to its “light” phase, only to which the Cartesian dichotomy of “body” and “mind” is valid; (2) quantum information conservation as relevant to the dark phase, furthermore generalizing energy conservation as to its light phase, productively allowing for physical entities to appear “ex nihilo”, i.e., from the dark phase, in which energy and time are yet inseparable from each other; (3) reversible causality as inherent to the dark phase; (4) the interpretation of gravitation only mathematically: as an interpretation of the incompleteness of finiteness to infinity, for example, following the Gödel dichotomy (“either contradiction or incompleteness”) about the relation of arithmetic to set theory; (5) the restriction of the concept of hierarchy only to the light phase; (6) the commensurability of both physical extremes of a quantum and the universe as a whole in the dark phase obeying quantum information conservation and akin to Nicholas of Cusa’s philosophical and theological worldview.

The purpose of this paper is to show a new approach to unify the theory of general relativity and quantum physics. For this, we rely on thermodynamics, fluid mechanics and the theory of information. We will then see that the Shannon entropy, Boltzmann and Von Neumann can be the source of gravity, which would be a form emerging. For this, we will study at first what is lacking for the unification of general relativity and physics. Secondly, we will explain the concept of entropic gravity by introducing calculations Erik Verlinde. Then we will explain the concept of entropy Boltzmann, Shannon, Von Neumann and the links between them. Then, we will modify Einstein's equations by transforming the tensor of perfect fluid in terms of entropy. Finally, we will link our theory with experience already carried out as part of a link between gravity and quantum theory.

In the Valpolicella area (Verona - Italy) Vitis vinifera cv. Corvina is the main grape variety used to produce Amarone wine. Before starting the winemaking process, the Corvina grapes are stored in a withering (i.e., dehydrating) warehouse until about 30% of the berry weight is lost (WL). This practice is followed to have the chemical metabolites concentrate in the berry and enrich the Amarone wine in aroma and antioxidant compounds. In compliance with the guidelines and strict Amarone protocol set by the Consorzio of Amarone-Valpolicella, withering must be carried out by setting the grapes in a suitable environment, either under controlled relative air humidity (RH) conditions and wind speed (WS) – no temperature modification is to be applied – or, following the traditional methods, in open-air natural environmental conditions. In general, the two processes have different dehydration kinetics due to the different conditions in terms of temperature, RH, and WS, which affect the accumulation of sugars and organic acids and the biosynthesis of sec-ondary metabolites such as stilbenes and glycoside aroma precursors. For this study, the two grape-withering processes were carried out under controlled (C) and not-controlled (NC) condi-tions and the final compositions of the Corvina dried grapes were compared also to evaluate the effects on the organoleptic characteristics of Amarone wine. The findings highlighted differences between the two processes mainly in terms of the secondary metabolites of the dried grapes, which affect the organoleptic characteristics of Amarone wine.

At present, there are no hardware or biochemical systems allow to assess the severity of post-COVID syndrome in vivo. The hardware of the proposed biotechnical system is based on routine transthoracic electrical impedance rheography, which makes it possible to register the frequency characteristics of the patient's bioimpedance response to controlled stress stimulation, thereby simultaneously fixing the characteristics of his productive heart, the state of the hemomicrocirculatory bed, the efficiency of the gas transport function of his blood, and also reliably assess personal reactivity and adaptive potential. Subsequent mathematical approximation of the obtained biometric data by an original neural network makes it possible to rank the results obtained and automatically generate a program of medical rehabilitation for a particular patient, depending on the severity of his post-COVID syndrome. The study results proved two reliable physiological signs confirming the presence of latent post-COVID complications: a decrease in the base impedance value for light exercise and an increase in the length of the systolic arc of the rheocardiogram.

Quantum Computation, in the gate array version, uses logical gates adopting convenient forms for computational algorithms based on those of classical computation. There, two-level quantum systems are the basic elements connecting the binary nature of classical computation with the settlement of quantum processing. Despite, their design depends on specific quantum systems and physical interactions involved, exacerbating the dynamics analysis. Predictable and controllable manipulation should be addressed to control the quantum states, but resources are restricted to limitations imposed by the physical settlement. This work presents a formalism to decompose the quantum information dynamics in SU(2^2d) for 2d-partite two-level systems into 2^2d-1 SU(2) quantum subsystems. Decomposition lets to set control procedures, to generate large entangled states and to design specialized dedicated quantum gates. There, easy and traditional operations proposed by quantum computation are recovered for more complex and large systems. Alternating the parameters of local and non-local interactions, the procedure states a universal exchange semantics on the generalized Bell states basis. It could be understood as a momentary splitting of the 2d information channels into 2^2d-1 pairs of 2 level quantum information subsystems and a settlement of the quantum information manipulation free of the imposed restrictions by the underlying physical system.

The article presents the author's results of studying hidden rules of structural organizations of long DNA sequences in eukaryotic and prokaryotic genomes. The results concern some rules of percentages (or probabilities) of n-plets in genomes. To reveal such rules, the author considers genomic DNA nucleotide sequences as multilayers sequences of n-plets and studies the percentage contents of n-plets in different layers. Unexpected rules of invariance of total sums of percentages in certain tetra-groupings of n-plets in different layers of genomic DNA sequences are revealed. These discovered rules are candidates for the role of universal genomic rules. A tensor family of matrix representations of interrelated DNA-alphabets of 4 nucleotides, 16 doublets, 64 triplets, and 256 tetraplets is used in the study. This matrix approach allows revealing algebraic properties of the mentioned genetic rules of probabilities, which are useful for developing algebraic and quantum biology. Some analogies of the discovered genetic phenomena with phenomena of Gestalt psychology are noted and discussed. The author connects the received results about the genomic percentages rules with a supposition of P. Jordan, who is one of the creators of quantum mechanics and quantum biology, that life's missing laws are the rules of chance and probability of the quantum world. Additional attention is paid to the algebraic features of the system of structured DNA alphabets and their relationship with the methods of algebraic holography, known in the technique of processing discrete signals. The concept of algebraic-holographic genetics is being developed for the understanding of inherited holographic properties of organisms.

In this paper the development process of a deployable modular sandwich panelized system for rapid assembly building construction is presented, and its structural performance under some different action effects is investigated. This system, which includes an innovative sandwich panel and its integrated connections, can be used as structural walls and floors in quickly assembled post-disaster housing, as well as load bearing panels for pre-fabricated modular construction and semi-permanent buildings. Panels and connections are composed of a pneumatic fabric formwork, and two 3-D high-density polyethylene (HDPE) sheets as the skins, filled with high-density rigid Polyurethane (PU) foam as the core. HDPE sheets manufactured with a studded surface considerably enhance the stress distribution, buckling performance and delamination strength of the sandwich panel under various loading conditions. The load-carrying behaviour of the system in accordance with some ASTM standards is presented here. The results show the system satisfies the codes criteria regarding semi-permanent housing.

Land-cover classification that uses very-high-resolution (VHR) remote sensing images is a topic of considerable interest. Although many classification methods have been developed, there is still room for improvements in the accuracy and usability of classification systems. In this paper, a novel post-processing approach based on a dual-adaptive majority voting strategy (D-AMVS) is proposed for improving the performance of initial classification maps. D-AMVS defines a strategy for refining each label of a classified map that is obtained by different classification methods from the same original image and fusing the different refined classification maps to generate a final classification result. The proposed D-AMVS contains three main blocks. 1) An adaptive region is generated by extending gradually the region around a central pixel based on two predefined parameters (T1 and T2) in order to utilize the spatial feature of ground targets in a VHR image. 2) For each classified map, the label of the central pixel is refined according to the majority voting rule within the adaptive region. This is defined as adaptive majority voting (AMV). Each initial classified map is refined in this manner pixel by pixel. 3) Finally, the refined classified maps are used to generate a final classification map, and the label of the central pixel in the final classification map is determined by applying AMV again. Each entire classified map is scanned and refined pixel by pixel based on the proposed D-AMVS. The accuracies of the proposed D-AMVS approach are investigated through two remote sensing images with high spatial resolutions of 1.0 and 1.3 m, respectively. Compared with the classical majority voting method and a relatively new post-processing method called general post-classification framework, the proposed D-AMVS can achieve a land-cover classification map with less noise and higher classification accuracies.

The evolution of life on the planet Earth is happening primarily in the universe and secondary on the Earth. We will examine in this article evolution of life as the cosmic phenomena. In our model multidimensional time-invariant superfluid quantum space that is the fundamental arena of the universe and represents about 95% of the energy in the universe has stable entropy. The increase of entropy happens only by about 5% of the energy in the universe that is in the form of matter. The evolution of life in our model is a process of matter organization into living systems that tends to develop towards the constant entropy of the time-invariant multidimensional quantum space. This process runs in the entire universe. The development of life into intelligent organisms is the universal process running throughout the entire universe.

Macromolecular crystallography at cryogenic temperatures has so far provided the majority of the experimental evidence that underpins the determination of the atomic structures of proteins and other biomolecular assemblies by means of single crystal X-ray diffraction experiments. One of the core limitations of the current methods is that crystal samples degrade as they are subject to X-rays, and two broad groups of effects are observed: global and specific damage. While the currently successful approach is to operate outside the range where global damage is observed, specific damage is not well understood and may lead to poor interpretation of the chemistry and biology of the system under study. In this work, we present a phenomenological model in which specific damage is understood as the result of a single process, the steady excitation of crystal electrons caused by X-ray absorption, which acts as a trigger for the bulk effects that manifest themselves in the form of global damage and obscure the interpretation of chemical information from XFEL and synchrotron structural research.

A radical, albeit pragmatic protocol for experimental access to putative String/M-theoretic, Einstein Unified Field Mechanical (UFM) additional dimensionality (XD) of the brane-bouquet bulk is presented. If successful, results demonstrate the existence dimensionality beyond the metric of observed physical reality provided by the Standard Model (SM) of particle physics and Cosmology. Quantum Mechanics (QM), as well-known is incomplete and further, should no longer be considered the basement of reality; meaning, Locality and Unitarity – the fundaments of quantum theory are an insufficient basis for extending the representation of reality. A seminal model of Tight Bound States (TBS) below the lowest Bohr orbit in the hydrogen atom, proposed by Vigier, is extended to a Kaluza-Klein-like (KK) cyclical tier of XD hyperspherical cavities defined within a manifold of uncertainty (MOU) of finite radius up to the semi-quantum limit, predicting, within its domain, new spectral lines in Hydrogen. The proposed protocol for this process, with phase modifications, provides efficacy of large-scale additional dimensionality (LSXD) of the brane bulk; XD-LSXD incursion duality accesses nonlocal Einsteinian UFM phenomena, leading to myriad new classes of technological innovation.

Quantum theory predicts a whole class of non-local phenomena, observable via coincident detection of EPR-type systems. An important feature of these observations is their non-signaling character. Technically, non-local phenomena should only be observable for post-selected sub-ensembles, rather than for complete projections. Otherwise, superluminal telegraphy becomes possible. Yet, a couple of recent Bell experiments reported the observation of quantum non-locality for 100% of the detected events. Does it follow that signaling non-locality is possible? If so, was quantum theory falsified? This puzzle is solved by revisiting the interpretation of the spin projection operator, with special focus on its dual nature (combining spectral decomposition with spectral transformation). “Component switching” is not a loophole, but rather a requirement of quantum mechanics in this context, because sharp spin projections are partial (as well as partially overlapping). Surprisingly, it is possible to pre-select incompatible statistical sub-ensembles with heralded detection and to reveal the same behavior as in post-selected observations. Therefore, Bell experiments confirm the predictions of quantum theory without violating the non-signaling principle.

We study the resonant dipole-dipole interaction energy between two uniformly accelerated identical atoms, one excited and the other in the ground state, prepared in a correlated Bell-type state, and interacting with the scalar field or the electromagnetic field nearby a perfectly reflecting plate. We suppose the two atoms moving with the same uniform acceleration, parallel to the plane boundary, and that their separation is constant during the motion. We separate the contributions of vacuum fluctuations and radiation reaction field to the resonance energy shift of the two-atom system, and show that Unruh thermal fluctuations do not affect the resonance interaction, which is exclusively related to the radiation reaction field. However, nonthermal effects of acceleration in the radiation-reaction contribution, beyond the Unruh acceleration-temperature equivalence, affect the resonance interaction energy. By considering specific geometric configurations of the two-atom system relative to the plate, we show that the presence of the mirror significantly modifies the resonance interaction energy between the two accelerated atoms. In particular, we find that new and different features appear with respect to the case of atoms in the free space, related to the presence of the boundary and to the peculiar structure of the quantum electromagnetic field vacuum in the locally inertial frame. Our results suggest the possibility to exploit the resonance interaction between accelerated atoms, as a probe for detecting the elusive effects of atomic acceleration on radiative processes.

In this article we derive a closed form expression for the symmetric logarithmic derivative of Fermionic Gaussian states. This provides a direct way of computing the quantum Fisher Information for Fermionic Gaussian states. Applications range from quantum Metrology with thermal states to non-equilibrium steady states with Fermionic many-body systems.

The question of what generates conscious experience has mesmerized thinkers since the dawn of humanity, yet its origins remain a mystery. The topic of consciousness has gained traction in recent years, thanks to the development of large language models that now arguably pass the Turing test, an operational test for intelligence. However, intelligence and consciousness are not related in obvious ways, as anyone who suffers from a bad toothache can attest - pain generates intense feelings and absorbs all our conscious awareness yet nothing particularly intelligent is going on. Still, in the hard sciences, this topic is frequently met with skepticism because to date no protocol to measure the content or intensity of conscious experiences in an observer-independent manner has been agreed upon. Here we present a novel proposal: Conscious experience arises whenever a quantum mechanical superposition forms. Our proposal has several implications: First, it suggests that the structure of the superposition determines the qualia of the experience. Second, quantum entanglement naturally solves the binding problem, ensuring the unity of phenomenal experience. Finally, a moment of agency may coincide with the formation of a superposition state. We outline a research program to experimentally test our conjecture via a sequence of quantum biology experiments. Applying these ideas opens up the possibility of expanding human experience through brain-quantum computer interfaces.

Background: Many randomized controlled trials (RCTs) and systematic reviews (SRs) on acupuncture treatment for post-acute stroke dysphagia have been published. Due to conflicting results an overview of SRs to summarize and assess the quality of this evidence to determine whether acupuncture is effective for this disease was conducted. Methods: Seven databases were searched for SRs and/or Meta-analysis of RCTs and quasi-RCTs on acupuncture for post-acute stroke dysphagia. Two authors independently identified SRs and meta-analyses, collected data to assess the quality of included SRs and meta analyses according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and the revised Assessment of Multiple Systematic Reviews (AMSTAR 2). Results: 31 SRs were identified. Quality of 22 SRs was critically low, 5 SRs were low, and 4 Cochrane SRs were moderate when evaluated by AMSTAR2. 17 SRs reported 85.2-96.3% items of PRISMA. Five SRs included explanatory RCTs, 16 SRs included pragmatic RCTs, and 10 SRs included both. Conclusion: Currently evidence on the effectiveness of acupuncture on post-acute stroke dysphagia is low quality. Type of study appeared to have no direct influence on the result, but the primary outcome measures showed a relationship with the quality of SRs. High quality trials with large sample sizes should be the focus of future research. PROSPERO REGISTRATION NUMBER: CRD42019134163

Background: This study investigated the prevalence of worsening problems using Post Stroke Checklist (PSC) at 3, 6, and 12 months post-stroke and their associations with health-related quality of life. Methods: In stroke patients admitted between June 2014 and December 2015, PSC and EuroQol-5Dthree level (EQ-5D-3L) were assessed at post-stroke 3 (n=181), 6 (n=175), and 12months (n=89). The prevalence of worsening problems and its association withEQ-5D-3L at post-stroke 3 and 6months were analyzed. Results: An average of 0.59 (range 0–12), 1.47 (range 0–12), and 1.00 (range 0–10) worsening problems per patient was identified at 3, 6, and 12months after stroke, respectively. The most frequently and continuously identified worsening problems were mood disturbances (reported by 8.8%, 16.0% and13.5% of patients at 3, 6, and 12 months post-stroke, respectively). Worsening mobility was significantly associated with worse EQ-5D index at post-stroke 3 months (β,-0.583; 95% CI, -1.045 to -0.120). The worsening of mobility and communication was significantly associated with worse EQ-5D index at post-stroke 6 months (mobility: β,-0.170; 95% CI, -0.305 to -0.034, communication: β,-0.164; 95% CI, -0.309 to -0.020). Conclusions: PSC may be useful for the detection of various subjective worsening problems during serial clinical follow-up after stroke. Appropriate rehabilitation and management strategy to solve the identified problems could improve the quality of life in stroke survivors.

Highly-correlated electrons – electrons that engage in strong electron-electron interactions – have been observed in transition metal oxides and quantum dots and can create unusual material behavior that is difficult to model, such as switching between a low resistance metal state and a high resistance Mott insulator state. Tests of devices using a layer-by-layer deposition process for forming multilayer arrays of ferritin (a transition metal (iron) oxide storage protein) have been previously reported that indicate that highly-correlated electron transport is occurring, consistent with models of electron transport in quantum dots. This paper reports the results of the effect of various degrees of structural homogeneity on the electrical characteristics of these ferritin arrays, as well as demonstrating that these structures can provide a switching function associated with the circuit that they are contained within, consistent with the observed behavior of highly-correlated electrons.

Several mathematicians and physicists are working all over the globe to get a unified theory. However, most of them are discarding Einstein’s view at the very first step of their theories. This article provides a brief description about this. Also, on the basis of Koga’s theory we point out two reasons which might have caused Einstein’s failure to get a unified theory.

In 1935 Einstein, Podolsky, and Rosen (EPR) studied general entangled states in the two photon experiment and pointed out the contradiction between local realism and the completeness of quantum mechanism. Most of the EPR experiments in recent years are based on the detection of polarization correlations of optical photons between spatially separated photon channels, some of which are split and directed to two spatially separated Michelson interferometers. Later, the two arms of Michelson interferometers are replaced by dual-channel Fabry-Perot (F-P) interferometry enabling precise analysis of the energy-time entanglement between a pair of photons. On the other hand, F-P type detectors on gravitational radiation have caught dozens of gravitational wave (GW) events successfully. This paper proposes a combined experiment of EPR and GW, exhibiting whether the coincident rate of EPR is modulated by GW induced change of cavity length or not. Such an experiment could test the coupling of quantum mechanics and general relativity for the first time, and be a useful tool to explore the nature of quantum gravity.

We describe results from a Monte-Carlo simulation of Bell-CHSH type correlations in hydrodynamic walkers. We study feasibility of a real life walker test with relevant hydrodynamic parametric ranges. We observe the generic formation of pairs of walkers strongly anti-correlated both in position and momentum. With this source of entangled walkers, we model the insertion of 2 pins in the bath as a notion of measure, akin to the polarizers of photonic Bell tests. This insertion of pins, either static or dynamic, introduces 2 weak field signals. Each field has the physical form of a standing wave Bessel hat, representing the non-local (field mediated) influences of the measure on the walkers. With this representation of the measure, we develop protocol for a Bell game with actual hydrodynamic walkers. We model both static and dynamic insertion of pins in the walker bath. Static pins give us numerical S > 2, as a permissible Bell violation for a non-local (field based) effect. Dynamic insertion of the pins, however, leads to causal space separation of the two arms. We observe the again expected S ≤ 2. We argue for the hydrodynamic implementation and observation of these effects as a walker visualization of Bell inequalities.

The Newton-Hooke duality and its generalization to arbitrary power laws in classical, semiclassical and quantum mechanics are discussed. We pursue a view that the power-law duality is a symmetry of the action under a set of duality operations. The power dual symmetry is defined by invariance and reciprocity of the action in the form of Hamilton’s characteristic function. We find that the power-law duality is basically a classical notion and breaks down at the level of angular quantization. We propose an ad hoc procedure to preserve the dual symmetry in quantum mechanics. The energy-coupling exchange maps required as part of the duality operations that take one system to another lead to an energy formula that relates the new energy to the old energy. The transformation property of Green function satisfying the radial Schrödinger equation yields a formula that relates the new Green function to the old one. The energy spectrum of the linear motion in a fractional power potential is semiclassically evaluated. We find a way to show the Coulomb-Hooke duality in the supersymmetric semiclassical action. We also study the confinement potential problem with the help of the dual structure of a two-term power potential.

In the past 100 years, quantum theory has achieved remarkable achievements and formed a relatively mature system, but at the same time there are still some incomplete places. For example: What is the origin of quantum? What is the origin of quantum entanglement? What is the origin of quantum mechanical wave-particle duality? This is still a problem that the existing quantum theory has not solved. Therefore, this paper attempts to seek a classic interpretation of quantum mechanics to make up for the shortcomings of existing quantum theory. In the latest research, this paper finds a classic interpretation of blackbody radiation, which can explain the discontinuity of light energy from the perspective of classical mechanics. Based on this discovery, this paper successfully explains the origin of quantum, quantum entanglement and wave-particle duality, and eliminates the confusion of quantum mechanical probability waves.

Applications in security and electronic surveillance require combination of excellent magnetic softness with good mechanical and anti-corrosive properties and low dimensionality. We overviewed the properties of soft magnetic glass-coated microwires and different post-processing making them quite attractive for electronic article surveillance and security applications. We studied the magnetostatic interaction between the microwires and routes to tune the non-linear hysteresis loops by using the arrays of different types of amorphous microwires. The presence of neighbouring microwire (either Fe or Co-based) significantly affects the hysteresis loop of the whole microwires array. In a microwires array containing magnetically bistable microwires we observed splitting of the initially rectangular hysteresis loop with a number of Barkhausen jumps correlated with the number of magnetically bistable microwires. Essentially, non-linear and irregular hysteresis loops have been observed in mixed arrays containing Fe and Co-rich microwires. The observed non-linearity in hysteresis loops allowed to increase the harmonics and tune their magnetic field dependencies. Non-linear hysteresis loops have been also observed upon devitrification of amorphous microwires. On the other hand, several routes allowing to tune the switching field by either post-processing or modifying the magnetoelastic anisotropy have been reviewed. Observed unique combination of magnetic properties together with thin dimensions and excellent mechanical and anti-corrosive properties provide excellent perspectives for the use of glass-coated microwires for security and electronic surveillance applications.

With reference to Planck scale, increasing support for large scale cosmic anisotropy and preferred directions and by considering an increasing ratio of Hubble parameter to angular velocity, right from the beginning of Planck scale, we make an attempt to estimate ordinary matter density ratio, dark matter density ratio, mass, radius, temperature, age and expansion velocity (from and about the baby universe in all directions). We would like suggest that, from the beginning of Planck scale, 1) Dark matter can be considered as a kind of cosmic foam responsible for formation of galaxies. 2) Cosmic angular velocity decreases with square of the decreasing cosmic temperature. 3) Increasing ratio of Hubble parameter to angular velocity plays a crucial role in estimating increasing cosmic expansion velocity and decreasing density ratios of dark matter and ordinary matter. 4) There is no need to consider dark energy for understanding cosmic acceleration.

We show that quantum mechanics can be constructed as a classical field theory that correctly describes all basic quantum effects, by combining the Maxwell and Dirac equations. It is shown that for a self-consistent union of the Maxwell and Dirac equations into a unified classical field theory, it is necessary to introduce an additional short-range tensor field, which compensates the intrinsic electrostatic field of the electron wave inside the atom. For the combined Maxwell-Dirac field, the stress-energy tensor is constructed. We show that in the nonrelativistic limit this theory naturally transforms into the self-consistent Maxwell-Pauli theory and allows describing all basic quantum effects in the framework of classical field theory without any quantization.

The goal of finding a commutative group of gates from the set of unitary matrices is to simplify the process of quantum computing. If a set of gates is commutative, then we can apply the gates in any order without affecting the final outcome. This is important because quantum systems are very sensitive to errors and decoherence, and any disruption to the system can cause errors in the computation.By having a commutative group of gates, we can simplify the process of designing quantum algorithms and reduce the risk of errors. This is particularly important for solving complex computational problems that cannot be solved by classical computers.

This paper is our attempt on the basis of physical theory to bring more clarification on the question ``What is life?'' formulated in the well-known book of Schr\"odinger in 1944. According to Schr\"odinger, the main distinguishing feature of biosystem's functioning is the ability to preserve its order structure or, in the mathematical terms, to prevent increasing of entropy. Since any biosystem is fundamentally open, it is natural to use open system's theory. However, Schr\"odinger's analysis shows that the classical theory is not able to adequately describe the order-stability in a biosystem. Schr\"odinger should also appeal to the ambiguous notion of negative entropy. We suggest to apply the quantum theory. As is well-known, behaviour of the quantum von Neumann entropy crucially differs from behaviour of the classical entropy. We consider a complex biosystem $S$ composed of many subsystems, say proteins, or cells, or neural networks in the brain, i.e., $S=(S_i).$ We study the following problem: if the composed system $S$ can preserve the ``global order'' in the situation of increase of local disorder and if $S$ can preserve its entropy while some of $S_i$ increase their entropies We show that within quantum information theory the answer is positive. The significant role plays entanglement of the subsystems states. In the absence of entanglement, increasing of local disorder generates disorder increasing in the compound system $S$ (as in the classical regime).

Inferring algorithmic structure in data is essential for discovering causal generative models. In this research, we present a quantum computing framework using the circuit model, for estimating algorithmic information metrics. The canonical computation model of the Turing machine is restricted in time and space resources, to make the target metrics computable under realistic assumptions. The universal prior distribution for the automata is obtained as a quantum superposition, which is further conditioned to estimate the metrics. Specific cases are explored where the quantum implementation offers polynomial advantage, in contrast to an indispensable exhaustive enumeration in the corresponding classical case. The unstructured output data and the computational irreducibility of Turing machines make this algorithm impossible to approximate using heuristics. Thus, exploring the space of program-output relations is one of the most promising problems for demonstrating quantum supremacy using Grover search that cannot be dequantized. Experimental use cases for quantum acceleration are developed for self-replicating programs and algorithmic complexity of short strings. With quantum computing hardware rapidly attaining technological maturity, we discuss how this framework will have significant advantage for various genomics applications in meta-biology, phylogenetic tree analysis, protein-protein interaction mapping and synthetic biology. This is the first time experimental algorithmic information theory is implemented using quantum computation. Our implementation on the Qiskit quantum programming platform is copy-left and can be found on https://github.com/Advanced-Research-Centre/QPULBA

Background: Whilst lack of concentration is a known symptom of anaemia, its association with post-stroke dementia is unclear. Methods: We used data from a UK regional stroke register. To be eligible, patient must have survived to discharge and had anaemia by WHO criteria. Dementia status and other prevalent co-morbidities were assessed using ICD-10 codes. Patients were followed till May 2015 (mean follow-up 3.7 years, total person years = 27,769). Hazard Ratio for incident dementia was calculated using Cox-proportional hazards model controlling for potential confounders. Fine and Gray model was additionally constructed using mortality as the competing risk. Results: A total of 7,454 stroke patients were included with mean age (SD) of 75.9(12.3) years (50.2% men). Those with anaemia were older, has higher disability and co-morbidity burden prior to stroke. We observed a large amount of variation in the dementia incidence rates over time and that the hazard ratio increased every year. The significant association between anaemia and dementia incidence was lost after controlling for pre-stroke Modified Rankin score (HR1.17(0.97,1.40)). With every 20g/dL increase in Hb was associated with a significant reduction in the risk of dementia after adjustment for age, sex, stroke factors and disability but lost significance after adjustment for vascular risk factors. Competing risk analyses showed similar results. Conclusion: Whilst we found no evidence of anaemia as a risk factor for post-stroke dementia, the findings may be limited by potential under recognition of post stroke dementia.

The presence of the quantum Rayleigh scattering, or spontaneous emission, inside a dielectric medium such as a beam splitter or an interferometric filter, prevents a single-photon from propagating in a straight-line. Modelling a beam splitter by means of a unitary transformation is physically meaningless because of the loss of photons. Additional missing elements from the conventional theory are: 1) the quantum Rayleigh stimulated emission which can form groups of photons of the same frequencies, and 2) the unavoidable parametric amplification of single-photons in the original parametric crystal. An interference filter disturbs, through multiple internal reflections, the original stream of single-photons, thereby confirming the existence of groups of photons being spread out to lengthen the coherence time. The approach of modelling individual, single measurements with statistical ensemble probability amplitudes leads to the counterintuitive explanations of the experimental outcomes and should be replaced with pure states describing instantaneous measurements which are afterwards averaged.

The usage of Quantum Similarity through the equation Z = {∀θ ∈ Z → ∃s ∈ S ∧ ∃t ∈ T : θ = (s, t)}, represents a way to analyze the way communication works in our DNA. Being able to create the object set reference for z being (s, t) in our DNA strands, we are able to set logical tags and representations of our DNA in a completely computational form. This will allow us to have a better understanding of the sequences that happen in our DNA. With this approach, we can also utilize mathematical formulas such as the Euler–Mascheroni constant, regression analysis, and computational proofs to answer important questions on Quantum biology, Quantum similarity, and Theoretical Physics.

The aim of the paper is to investigate Nash equilibria and correlated equilibria of classical and quantum games in the context of their Pareto optimality. We study four games: the prisoner's dilemma, battle of the sexes and two versions of the game of chicken. The correlated equilibria usually improve Nash equilibria of games but require a trusted correlation device. We analyze the quantum extension of these games in the Eisert-Wilkens-Lewenstein formalism with the full SU(2) space of players’ strategy parameters. It has been shown that the Nash equilibria of these games in quantum mixed Pauli strategies are closer to Pareto optimal results than their classical counterparts. The relationship of mixed Pauli strategies equilibria and correlated equilibria is also analyzed.

The spatial formation of coherent random laser modes in strongly scattering disordered random media is a central feature in the understanding of the physics of random lasers. We derive a quantum field theoretical method for random lasing in disordered samples of complex amplifying Mie resonators which is able to provide self-consistently and free of any fit parameter the full set of transport characteristics at and above the laser phase transition. The coherence length and the correlation volume respectively is derived as an experimentally measurable scale of the phase transition at the laser threshold. We find that the process of stimulated emission in extended disordered arrangements of active Mie resonators is ultimately connected to time-reversal symmetric multiple scattering in the sense of photonic transport while the diffusion coefficient is finite. A power law is found for the random laser mode diameters in stationary state with increasing pump intensity.

Several researchers have contemplated deep learning-based post-filters to increase the quality of statistical parametric speech synthesis, which perform a mapping of the synthetic speech to the natural speech, considering the different parameters separately and trying to reduce the gap between them. The Long Short-term Memory (LSTM) Neural Networks have been applied successfully in this purpose, but there are still many aspects to improve in the results and in the process itself. In this paper, we introduce a new pre-training approach for the LSTM, with the objective of enhancing the quality of the synthesized speech, particularly in the spectrum, in a more efficient manner. Our approach begins with an auto-associative training of one LSTM network, which is used as an initialization for the post-filters. We show the advantages of this initialization for the enhancing of the Mel-Frequency Cepstral parameters of synthetic speech. Results show that the initialization succeeds in achieving better results in enhancing the statistical parametric speech spectrum in most cases when compared to the common random initialization approach of the networks.

High-level quantum-chemical computations (G4MP2) are carried out in the study of complexes featuring tetrel bonding between the carbon atom in the carbenoid CB11H11 - obtained by hydride removal in the C-H bond of the known closo-monocarbadodecaborate anion CB11H12() and acting as Lewis acid (LA) - and Lewis bases (LB) of different type; the electron donor groups in the tetrel bond feature carbon, nitrogen, oxygen, fluorine, silicon, phosphorus, sulphur and chlorine atomic centers in neutral molecules as well as anions H(-), OH(-) and F(-). The empty radial 2pr vacant orbital on the carbon center in CB11H11 , which corresponds to the LUMO, acts as a Lewis acid or electron attractor, as shown by the molecular electrostatic potential (MEP) and electron localization funcion (ELF). The thermochemistry and topological analysis of the complexes {CB11H11:LB} are comprehensively analyzed, and classified according to sharing or closed-shell interactions. ELF analysis shows that the tetrel C···X bond ranges from very polarised bonds, as in H11B11C:F() to very weak interactions as in H11B11C···FH and H11B11C···O=C=O.

Currently, there are two approaches to the foundations of thermodynamics. One, associated with the mechanistical Clausius-Boltzmann tradition, is favored by the physics community. The other, associated with the post-mechanical Carnot tradition, is favored by the engineering community. The bold hypothesis is that the conceptual foundation of engineering thermodynamics is the more comprehensive. Therefore, contrary to the dominant consensus, engineering thermodynamics (ET) represents the true foundation of thermodynamics. The foundational issue is crucial to a number of unresolved current and historical issues in thermodynamic theory and practice. ET formally explains the limited successes of the ‘rational mechanical’ approaches as idealizing special cases. Thermodynamic phenomena are uniquely dissymmetric and can never be completely understood in terms of symmetry-based mechanical concepts. Consequently, ET understands thermodynamic phenomena in new way, in terms of the post-mechanical formulation of action. The ET concept of action and the action framework trace back to Maupertuis’s Principle of Least Action, both clarified in the engineering worldview research program of Lazare and Sadi Carnot. Despite the intervening Lagrangian ‘mechanical idealization of action’, the original dualistic, indeterminate engineering understanding of action, somewhat unexpectedly, re-emerged in Planck’s quantum of action. The link between engineering thermodynamics and quantum theory is not spurious and each of our current formulations helps us develop our understanding of the other. Both the ET and quantum theory understandings of thermodynamic phenomena, as essentially dissymmetric (viz. embracing complementary), entail that there must be an irreducible, cumulative historical, qualitatively emergent, aspect of reality.

For the better part of a century researchers across disciplines have sought to explain the crystallography of the elemental transition metals: hexagonal close packed, body centered cubic, and face centered cubic in a form similar to that used to rationalize the structure of organic molecules and inorganic complexes. Pauling himself tried with limited success to address the origins of transition metal stability. These early investigators were handicapped, however, by incomplete knowledge regarding the structure of metallic charge density. Here we exploit modern approaches to charge analysis to first comprehensively describe transition metal charge density. Then, we use topological partitioning and quantum mechanically rigorous treatments of kinetic energy to account for the structure of the density as arising from the interactions between metallic tetrahedra. We argue that the crystallography of the early transition metals results from charge transfer from the so called “octahedral” to “tetrahedral holes” while the face centered cubic structure of the late transition metals is a consequence of antibonding interactions that increase octahedral hole kinetic energy.

Abstract: I present a generalization of quantum electrodynamics which includes Diracmagnetic monop oles and the Salam magnetic photon. This quantum electromagnetodynamics has many attractive features. (1) It explains the quantization of electric charge. (2) It describes symmetrized Maxwell equations. (3) It is manifestly covariant. (4) It describes local four-potentials. (5) It avoids the unphysical Dirac string. (6) It predicts a second kind of electromagnetic radiation which can be veri ed by a tabletop experiment. An eect of this radiation may have been observed by August Kundt in 1885. Furthermore I discuss a generalization of General Relativity which includes Cartan's torsion. I discuss the mathematical de nition, concrete description, and physical meaning of Cartan's torsion. I argue that the electric-magnetic duality of quantum electromagnetodynamics is analogous to the spin-mass duality of Einstein-Cartan theory. A quantum version of this theory requires that the torsion tensor corresponds to a spin-3 boson called tordion which is shown to have a rest mass close to the Planck mass. Moreover I present an empirically satis ed fundamental equation of uni ed eld theory which includes the fundamental constants of electromagnetism and gravity. I conclude with the remark that the concepts presented here require neither Grand Uni cation nor supersymmetry.

Fire-tolerant eucalypt forests of south eastern Australia are assumed to fully recover from even the most intense fires but surprisingly very few studies have quantitatively assessed that recovery. Accurate assessment of horizontal and vertical attributes of tree crowns after fire is essential to understand the fire’s legacy effects on tree growth and on forest structure. In this study, we quantitatively assessed individual tree crowns 8.5 years after a 2009 wildfire that burnt extensive areas of eucalypt forest in temperate Australia. We used airborne lidar data validated with field measurements to estimate multiple metrics that quantified the cover, density, and vertical distribution of individual-tree crowns in 51 plots of 0.05 ha in fire-tolerant eucalypt forest across four wildfire severity types (unburnt, low, moderate, high). Significant differences in the field-assessed mean height of fire scarring as a proportion of tree height, and in the proportions of trees with epicormic (stem) resprouts were consistent with the gradation in fire severity. Linear mixed-effects models indicated persistent effects of both moderate- and high-severity wildfire on tree crown architecture. Trees at high-severity sites had significantly less crown projection area and live crown width as a proportion of total crown width than those at unburnt and low-severity sites. Significant differences in lidar-based metrics (crown cover, evenness, leaf area density profiles) indicated that tree crowns at moderate- and high-severity sites were comparatively narrow and more evenly distributed down the tree stem. These conical-shaped crowns contrasted sharply with the rounded crowns of trees at unburnt and low-severity sites, and likely influenced both tree productivity and the accuracy of biomass allometric equations for nearly a decade after the fire. Our data provide a clear example of the utility of airborne lidar data for quantifying the impacts of disturbances at the scale of individual trees. Quantified effects of contrasting fire severities on the structure of resprouter tree crowns provide a strong basis for interpreting post-fire patterns in forest canopies and vegetation profiles in lidar and other remotely-sensed data at larger scales.

Background: Recently some photon models of a Wigner's friend experiment have led investigators to suggest objective reality does not exist, and to publish non-academic articles with such claims. The public is not equipped to evaluate the severe limitations of these experiments. The separation of Wigner from the experiment and use of only reversible coherent processes for the friend allow operations that are not possible in ordinary reality according to the latest quantum research. Methods: We suggest directly testing the implied claim that objective reality, including incoherent objects with irreversible non-destructive memory, can be held in superposition. We suspect it will fail, but provide for a graduated approach that may discover something about the conditions for superposition collapse. To this end we design a thought experiment to model the objective world, investigating under what conditions experimenters in the same world (ensemble member) will be able to record a result and find it does not appear to change. An observer has a viewing apparatus and a memory apparatus. A second uncorrelated viewer of the same recorded result is employed to obtain objectivity. By hypothesis the uncorrelated second viewer obtains the same view of the measurement record as the first observer. There are not two measurements. This is not an investigation of hidden variables. Results: To model the objective world, incoherent and irreversible processes must be included. To test for superposition, coherence has to be established. These seem to present a contradiction. Conclusions: The thought experiment has suggested new places to look other than size for the origin of objective reality from the quantum world, casts doubt on the Many-Worlds interpretation, and provides a method of testing it.

According to the current European and Italian scenario related to urban re-generation, cultural and landscape heritage, valorisation is being also enhanced by the activation of innovative processes. These involve the development of methodologies and tools that are able to address decision-making processes among low entropy economy, complex values and creative practices. In this perspective, the research aims to investigate the possibilities of developing a Cultural Heritage Low Entropy Enhancement (CHLEE) approach by considering how the complex values of cultural heritage can vary not only through a physical transformation of spaces but also through a program of uses and activities able to produce new values, where the human experience is essential. This type of model modifies the objectives that characterise the valorisation of cultural heritage and landscape, recognising that the fruition is no longer “consumerist” but “experiential”. A crucial role is represented by the heterogeneity of creative practices that contribute to the identificationidentifying and implementation ofimplementing innovative management and governance models. The present paper explores the components of creative regenerative processes, based upon the ex-post evaluation of some Italian experiments, across the PROMETHEE-GAIA multi-criteria method, to understand how creative experiences are building innovation ecosystem thanks to low entropy economy and improve the ex-ante evaluation for new strategies and policies.

Macrophage-derived chemokine belongs to the CC subfamily. It is produced by dendritic cells (DCs) and macrophages with or without external stimulation. We have previously shown a statistically significant depletion of MDC/CCL22 concentrations in a number of studies concerning COVID-19. These shifts in concentrations demonstrated stability unrelated to the SARS-CoV-2 genetic variant and remained noticeable even in convalescent patients. In this work, we analyze MDC/CCL22 dynamics in various diseases, including those that manifest with inflammation in lung tissue. In addition, we provide our hypothesis on such a decrease in MDC/CCL22 concentrations in COVID-19. If its secretion by producer cells is unperturbed, then it is possible for viral products to bind to this chemokine and to block its functional activity. There is, however, another possible explanation directly linked to depletion in DC subpopulations and the inhibition of their function. We also discuss MDC/CCL22's role in the immunology of novel coronavirus infection, based on both our own data and other studies.

For more than eighty years the standard interpretation (SI) has dominated quantum physics. Perspectives that have tried to challenge this domination have been remarkably unsuccessful. As a result, quantum theory (QT) has remained remarkably stagnant. The article offers a critical examination of SI and provides an explanation for its continued domination. It also uses Bohmian mechanics—a theoretical perspective advanced by American physicist David Bohm—as a case study for why alternative interpretations have failed to displace SI. The article sees the main reason for the failure to achieve much progress beyond SI in the unresolved philosophical problem of subject-object relation that continues to plague our study of physics. The article sketches a path to a possible solution and outlines a new science practice that this solution will require.

The paper considers the symmetries of a bit of information corresponding to one, two or three qubits of quantum information and identifiable as the three basic symmetries of the Standard model, U(1), SU(2), and SU(3) accordingly. They refer to “empty qubits” (or the free variable of quantum information), i.e. those in which no point is chosen (recorded). The choice of a certain point violates those symmetries. It can be represented furthermore as the choice of a privileged reference frame (e.g. that of the Big Bang), which can be described exhaustively by means of 16 numbers (4 for position, 4 for velocity, and 8 for acceleration) independently of time, but in space-time continuum, and still one, 17th number is necessary for the mass of rest of the observer in it. The same 17 numbers describing exhaustively a privileged reference frame thus granted to be “zero”, respectively a certain violation of all the three symmetries of the Standard model or the “record” in a qubit in general, can be represented as 17 elementary wave functions (or classes of wave functions) after the bijection of natural and transfinite natural (ordinal) numbers in Hilbert arithmetic and further identified as those corresponding to the 17 elementary of particles of the Standard model. Two generalizations of the relevant concepts of general relativity are introduced: (1) “discrete reference frame” to the class of all arbitrarily accelerated reference frame constituting a smooth manifold; (2) a still more general principle of relativity to the general principle of relativity, and meaning the conservation of quantum information as to all discrete reference frames as to the smooth manifold of all reference frames of general relativity. Then, the bijective transition from an accelerated reference frame to the 17 elementary wave functions of the Standard model can be interpreted by the still more general principle of relativity as the equivalent redescription of a privileged reference frame: smooth into a discrete one. The conservation of quantum information related to the generalization of the concept of reference frame can be interpreted as restoring the concept of the ether, an absolutely immovable medium and reference frame in Newtonian mechanics, to which the relative motion can be interpreted as an absolute one, or logically: the relations, as properties. The new ether is to consist of qubits (or quantum information). One can track the conceptual pathway of the “ether” from Newtonian mechanics via special relativity, via general relativity, via quantum mechanics to the theory of quantum information (or “quantum mechanics and information”). The identification of entanglement and gravity can be considered also as a ‘byproduct” implied by the transition from the smooth “ether of special and general relativity’ to the “flat” ether of quantum mechanics and information. The qubit ether is out of the “temporal screen” in general and is depicted on it as both matter and energy, both dark and visible.

Formalism proofing general derivation, applying matrix properties operations, showing fundamental relationships with inner product to outer product has been advanced here. This general proof formalism has direct application with physics to quantify quantum density at micro scale level to time commutator at macro scale level. System of operator algebraic equations have been rigorously derived to obtain analytic solutions which are physically acceptable. Extended physics application will include metricizing towards unitarization to achieve gaging Hamiltonian mechanics to electromagnetic gravitational strong theory, towards grand unifying physics atomistic to astrophysics or vice versa via quantum relativistic general physics thereby patching to classical physics fields energy.

1) We shall discuss what modern interpretations say about the Heisenberg's uncertainties. These interpretations explain that a quantity begins to 'lose' meaning when a conjugate property begins to 'acquire' definite meaning. We know that a quantity losing meaning means that it has no fixed value and has an uncertainty . In this paper we look deeper into this interpretation and the outcome reveals more evidence of the quantity losing meaning. Newer insights appear. 2) We consider two extreme cases of hypothetical processes nature undergoes, without interference by a measurement: One, a system collapses to an energy eigenstate under the influence of a Hamiltonian instantaneously at a time $t$. This is thus what would happen if we would measure the system's energy. Next, when a particle becomes localised to a point at a time $t_0$ under the influence of a Hamiltonian. This is thus what would happen if we would measure the system's position. We shall prove that both these situations cannot arise under ordinary circumstances and thus measurement processes cannot be modelled by physical Hamiltonians.

We try to solve three decades-old physics challenges. List all elementary particles. Describe dark matter. Describe mechanisms that govern the rate of expansion of the universe. We propose new modeling. The modeling uses extensions to harmonic oscillator mathematics. The modeling points to all known elementary particles. The modeling suggests new particles. Based on those results, we do the following. We explain observed ratios of dark matter amounts to ordinary matter amounts. We suggest details about galaxy formation. We suggest details about inflation. We suggest aspects regarding changes in the rate of expansion of the universe. We interrelate the masses of some elementary particles. We interrelate the strengths of electromagnetism and gravity. Our work seems to offer new insight regarding applications of harmonic oscillator mathematics. Our work seems to offer new insight regarding three branches of physics. The branches are elementary particles, astrophysics, and cosmology.

This paper is devoted to investigate charged vector particles tunneling via horizons of a pair of accelerating rotating charged NUT black hole under the influence of quantum gravitational effects. For this purpose, we use the modified Proca equation incorporating generalized uncertainty principle. Using the WKB approximation to the field equation, we obtain a modified tunneling rate and the corresponding corrected Hawking temperature for this black hole. Moreover, we analyze the graphical behavior of corrected Hawking temperature T'_H with respect to the event horizon for the given black hole. By considering quantum gravitational effects on Hawking temperatures, we discuss the stability analysis of this black hole. For a pair of black holes, the temperature T'_H increases with the increase in rotation parameters α and w, correction parameter β, black hole acceleration α and arbitrary parameter k and decreases with the increase in electric e and magnetic charges g.

In this article various heuristic approaches are discussed to solve the dark matter phenomenon by the concept of vacuum polarization. They are compared with a more fundamental approach, based upon an entropy model of the visible universe. They all make use of some kind of gravitational dipole. These dipoles seem to violate Einstein’s equivalence principle between inertial mass and gravitational mass. It is shown how the paradox can be solved by a quantum mechanical principle.