ARTICLE
|
doi:10.20944/preprints202212.0063.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Herpes simplex virus type 1 (HSV-1); antigen-receptor binding; equilibrium constant; Gibbs energy of binding; biothermodynamics
Online: 5 December 2022 (07:07:46 CET)
ARTICLE
|
doi:10.20944/preprints202211.0482.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Biothermodynamics of viruses; HIV-1; Binding constant; Gibbs energy of binding; Antigen-receptor binding
Online: 25 November 2022 (12:44:38 CET)
ARTICLE
|
doi:10.20944/preprints202210.0323.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
walnut; RNA interference; Argonaute (AGO); Dicer-like (DCL); RNA-dependent RNA polymerase (RDR); double-stranded RNA-binding (DRB); evolution; expression characteristics
Online: 21 October 2022 (08:03:38 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0450.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Heslington brain; intrinsically disordered protein; intrinsically disordered region; binding-induced folding; disorder-to-order transition
Online: 29 September 2022 (03:49:27 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0348.v1
Subject:
Physical Sciences,
Mathematical Physics
Keywords:
coupling constants; natural constants; neutrino mass; Higgs mass; Z boson mass; proton mass; nuclear binding; interaction function
Online: 23 September 2022 (02:04:12 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0318.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
BA.2.75 variant; Gibbs energy of binding; binding rate; infectivity; SARS-CoV-2
Online: 21 September 2022 (09:44:34 CEST)
REVIEW
|
doi:10.20944/preprints202209.0125.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Human serum albumin; COVID-19 vulnerabilities; fluid therapy; albumin binding deficiency; lymphatic nutrient pump; colloid pressure; interstitial spaces; albumin infusion; hepatic portal vein
Online: 8 September 2022 (13:40:16 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0439.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
acetylcholine binding protein; acetylcholinesterase; green pesticide, molecular docking
Online: 26 August 2022 (03:21:21 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0331.v1
Subject:
Computer Science And Mathematics,
Information Systems
Keywords:
Drug-Target Binding Affinity; Multi-Instance Learning; Transformer
Online: 18 August 2022 (03:58:34 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0213.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
intermolecular binding affinity; drug target binding affinity; computer-aided drug design (CADD); artificial intelligence-integrated drug discovery (AIDD); machine learning
Online: 11 August 2022 (08:40:37 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0126.v1
Subject:
Chemistry And Materials Science,
Applied Chemistry
Keywords:
Eugenol; Essential oils; Nanoencapsulation; Biopesticides; Insecticides; Odorant binding proteins; Inverted virtual screening
Online: 5 August 2022 (14:43:22 CEST)
ARTICLE
|
doi:10.20944/preprints202207.0058.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
human interferon gamma; human interferon gamma receptor; receptor binding; heparan sulfate; co-receptor; molecular dynamics simulations; sodium chlorate; kynurenine antiproliferative assays; hIFNγ signalling
Online: 5 July 2022 (04:43:05 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0348.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Naltrexone; mu-opioid receptor; MD simulations; MMGBSA; binding free energy
Online: 27 June 2022 (04:09:30 CEST)
REVIEW
|
doi:10.20944/preprints202206.0253.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Bioinorganic chemistry; metal-binding; structural biology; zinc; iron; copper; transition metals
Online: 17 June 2022 (09:30:07 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0201.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
human coronaviruses; envelope protein; PDZ-binding motif (PBM), homology-based modelling; docking; HADDOCK; protein-protein interaction; PALS1; pathogenesis; SARS-CoV-2
Online: 14 June 2022 (09:52:47 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0392.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
atrial-fibrillation; multi-target; drug promiscuity; druggable binding site; flecainide; Nav1.5; Kv1.5; binding site comparison; polypharmacology
Online: 30 May 2022 (10:10:41 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0366.v1
Subject:
Physical Sciences,
Condensed Matter Physics
Keywords:
Electron-phonon coupling; Nanoparticle; Ultrathin layer; Nonthermal melting; Tight-binding molecular dynamics; Boltzmann collision integrals; XTANT
Online: 26 May 2022 (10:44:54 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0336.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Long non-coding RNA; Prostate androgen-regulated transcript 1; miR-204-3p; insulin-like growth factor binding protein 2
Online: 24 May 2022 (11:57:26 CEST)
ARTICLE
|
doi:10.20944/preprints202201.0365.v3
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
binding affinity prediction; machine learning; data quality; data quantity; deep learning
Online: 23 May 2022 (11:16:49 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0280.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
purine-rich element binding protein A gene; PURA; MIM: 600473; transcriptional activator protein Pur-alpha; cognitive developmental delay; mental retardation; Mutation c.697_699del p.Phe233del
Online: 20 May 2022 (16:58:04 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202204.0194.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
antibody; binding energy; binding landscape; logistic function; network
Online: 21 April 2022 (08:10:03 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0165.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
Coronavirus SARS-CoV-2; seroprevalence; antibodies; nucleocapsid antigen; antigen receptor binding domain; seropositivity; St. Petersburg; volunteers; vaccination
Online: 18 April 2022 (10:42:54 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0091.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
SARS-CoV-2; SARS-CoV; RT-PCR; Sanger sequencing; RT-qPCR; receptor-binding domain (RBD); N-terminal domain (NTD); Omicron; multi-allelic SNPs; false-positive
Online: 12 April 2022 (03:57:29 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0075.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2; Antibody binding assays; binding antibody units; Immunocompromised; Threshold
Online: 8 April 2022 (08:38:40 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0328.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Zika Virus; Flavonoids; Azadirachta indica; Molecular Docking; Molecular Dynamics Simulation; Binding free energy
Online: 24 March 2022 (09:31:59 CET)
ARTICLE
|
doi:10.20944/preprints202203.0034.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Hemopexin; Hemoglobin; protein-protein binding; hemin
Online: 2 March 2022 (06:56:02 CET)
ARTICLE
|
doi:10.20944/preprints202202.0326.v1
Subject:
Computer Science And Mathematics,
Computer Science
Keywords:
Binding Problem; Perceptual Binding; Consciousness; Perception
Online: 25 February 2022 (08:46:39 CET)
ARTICLE
|
doi:10.20944/preprints202202.0118.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
protein-DNA interactions; DNA recognition; transcription factors; DNA binding domains; con-formational change; nuclear magnetic resonance; circular dichroism; control of gene expression; homeodomains.
Online: 8 February 2022 (14:53:06 CET)
ARTICLE
|
doi:10.20944/preprints202201.0328.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
cytochrome oxidase; thyroid hormones; steroid hormones; Bile Acids Binding Site; regulation
Online: 21 January 2022 (13:36:04 CET)
ARTICLE
|
doi:10.20944/preprints202112.0071.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Phaseolus vulgaris; Colletotrichum lindemuthianum; RNA silencing; Argonaute; double-stranded RNA binding (DRB); RNA-dependent RNA polymerase (RDR); Pol IV
Online: 6 December 2021 (12:42:51 CET)
ARTICLE
|
doi:10.20944/preprints202111.0322.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
binding agent; disintegrating agent; natural polymer; mucilage; Coccinia grandis
Online: 18 November 2021 (11:14:32 CET)
ARTICLE
|
doi:10.20944/preprints202110.0384.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
thiadizines; serotonin transporter (SERT); serotonin-1A receptor; serotonin-3 receptor; docking; docking energy; binding affinity; binding mechanism; c-Fos; immunohistochemistry; electrophysiology
Online: 26 October 2021 (12:32:43 CEST)
REVIEW
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
vitamin A transporters; all-trans retinol; retinyl esters; LRAT; STRA6; RBPR2; RBP4; retinol-binding proteins; photoreceptors; visual function
Online: 11 October 2021 (14:15:27 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0333.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
small RNA Oxys; RNA chaperone Hfq protein; gene expression regulator; molecular dynamics simulations; binding free energy; interaction entropy
Online: 20 September 2021 (12:47:28 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0013.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
dextransucrases; GH70; lactic acid bacteria; sucrose-active enzymes; carbohydrate binding module; glucansucrase; cellulose binding domain; Leuconostoc
Online: 1 September 2021 (12:12:00 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0403.v1
Subject:
Engineering,
Bioengineering
Keywords:
Phytocompounds; Binding energy; ADMET; Molecular docking
Online: 19 August 2021 (12:05:34 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0269.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
mannose-binding lectin; Oreochromis niloticus lectin; TiO2 nanotubes; biocompatibility; osseointegration.
Online: 12 August 2021 (08:42:44 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0137.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNA binding proteins; SF1; Hrb87F; Bru1; Drosophila; flight muscle; RNAi; splicing
Online: 5 August 2021 (10:42:09 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0109.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Membranous glomerulonephritis (MGN); Retinol binding protein (RBP); Prognostication; End-stage renal diseases
Online: 4 August 2021 (12:06:22 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0531.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
A.thaliana; HaloTag; RNA-binding proteins; RNA pulldown assay; RNA-protein complexes; cold shock domain protein
Online: 23 July 2021 (09:32:28 CEST)
COMMUNICATION
|
doi:10.20944/preprints202107.0500.v1
Subject:
Engineering,
Automotive Engineering
Keywords:
Clinching; binding mechanism; process chain; torsion test; electrical test
Online: 21 July 2021 (15:33:17 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0295.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2 spike protein; ACE2 host receptor; nanobodies; molecular dynamics; mutational sensitivity; binding free energy; allosteric interactions; signal transmission
Online: 13 July 2021 (11:18:02 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0635.v1
Subject:
Social Sciences,
Psychology
Keywords:
Fast learning; Bayes’ theorem; navigation; language; spatial cognition; feature structures; unification; generalization; dynamic binding; metadata multiplexing.
Online: 28 June 2021 (10:06:07 CEST)
REVIEW
|
doi:10.20944/preprints202106.0377.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
aa = amino acids; ACE-2 = receptor angiotensin-converting enzyme 2; cDNA = complementary DNA; mRNA = messenger RNA; orf = open reading frame; RBD = receptor binding protein; S-protein = Spike protein; SARS-CoV-2 = severe respiratory syndrome coronavirus 2; Vaccines.
Online: 22 June 2021 (11:53:34 CEST)
COMMUNICATION
|
doi:10.20944/preprints202106.0309.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
mTORC1; RHEB; G-Protein; Allosteric activation; Kinase domain; Binding kinetics
Online: 11 June 2021 (09:14:14 CEST)
COMMUNICATION
|
doi:10.20944/preprints202106.0091.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
COVID-19; SARS-CoV-2 variant; lateral flow immunoassay; spike protein; receptor binding domain (RBD); neutralizing antibody; therapeutic antibody cocktail; epitope binning; rapid neutralization test; ACE2
Online: 2 June 2021 (16:11:29 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0041.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Leptin; Metabolism; Amyotrophic Lateral Sclerosis (ALS); TAR DNA binding protein (TDP-43).
Online: 2 April 2021 (11:09:21 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0708.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Adolescents; high sensitivity C-reactive protein; Insulin-like growth factor binding proteins; Obesity; Oxidized Low-Density Lipoprotein; Predictive diagnostics
Online: 29 March 2021 (16:33:20 CEST)
REVIEW
|
doi:10.20944/preprints202103.0643.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Fragile X Syndrome; FMRP, RNA-binding protein; Physiopathology; Genomic; Transcriptomic; Proteomic; Metabolomic
Online: 25 March 2021 (16:22:35 CET)
ARTICLE
|
doi:10.20944/preprints202103.0618.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Binding sites; Optimization; cell free bacteria condition for metal bio-sorbents
Online: 25 March 2021 (13:59:50 CET)
ARTICLE
|
doi:10.20944/preprints202103.0541.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
α-Amylase inhibition; Tannic acid; Mixing order; Binding interactions; Adsorption
Online: 22 March 2021 (15:35:35 CET)
ARTICLE
|
doi:10.20944/preprints202103.0452.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
fission yeast; kinesin-14; RNA-binding protein; mitotic spindle; heat stress
Online: 17 March 2021 (16:52:41 CET)
ARTICLE
Subject:
Physical Sciences,
Condensed Matter Physics
Keywords:
cold nuclear fusion; maximum binding energy per nucleon; nuclear experiment
Online: 11 March 2021 (14:15:22 CET)
ARTICLE
|
doi:10.20944/preprints202102.0589.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
serotonin transporter (SERT); thiadiazines; serotonin receptors 3 and 1A (5-HT3 and 5-HT1A); docking energy; binding affinity; binding mechanisms; electrophysiology in vivo
Online: 25 February 2021 (15:23:26 CET)
REVIEW
|
doi:10.20944/preprints202102.0572.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
muscle; circRNA; RNA binding protein; molecular interactions; function
Online: 25 February 2021 (10:09:04 CET)
ARTICLE
|
doi:10.20944/preprints202102.0525.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
HIV-RT; ribonuclease H; dual inhibitors; docking; putative binding
Online: 23 February 2021 (15:51:40 CET)
ARTICLE
|
doi:10.20944/preprints202102.0132.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
multidrug resistance protein 4; ATP-binding cassette (ABC) transporters; aging; retina; mouse; electroretinogram
Online: 4 February 2021 (10:58:06 CET)
REVIEW
|
doi:10.20944/preprints202101.0458.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
blood-brain barrier; transient receptor potential cation channels; ischemic stroke; neuroprotection; calcium signaling; cAMP response element-binding protein
Online: 25 January 2021 (09:20:51 CET)
ARTICLE
|
doi:10.20944/preprints202101.0434.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Speciation of Ni2+; Kinetics and mechanism; Hydrogen bonding; 5,10,15,20-tetrakis(N-methylpyridium-4-yl)porphyrinatonickel(II) tetracation; Outside binding; Chemotherapeutic agents
Online: 22 January 2021 (08:42:47 CET)
ARTICLE
Subject:
Physical Sciences,
Nuclear And High Energy Physics
Keywords:
4G model of final unification; Four gravitational constants; Unified nuclear binding energy scheme; Free or unbound nucleons; Strong interaction; Electroweak interaction
Online: 25 December 2020 (17:29:44 CET)
ARTICLE
|
doi:10.20944/preprints202012.0189.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Zika virus (ZIKV); TFs Binding Motifs; Transcription Factors (TFs)
Online: 8 December 2020 (09:47:18 CET)
ARTICLE
|
doi:10.20944/preprints202010.0196.v2
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
drug discovery; artificial intelligence; protein discovery; binding prediction; synthetic molecule generation; synthetic drug
Online: 20 November 2020 (11:30:03 CET)
ARTICLE
|
doi:10.20944/preprints202011.0524.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
zinc finger; protein; MM/GBSA; DNA binding; molecular dynamics; mutation; linkers
Online: 19 November 2020 (21:21:37 CET)
REVIEW
|
doi:10.20944/preprints202009.0727.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
vitamin D; muscle; parathyroid hormone; vitamin D-binding protein
Online: 30 September 2020 (08:11:15 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0283.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Decapod Crustaceans; dsRNA transport; Gene silencing mechanism; Serum dsRNA binding proteins; Systemic RNAi
Online: 13 September 2020 (12:09:03 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0046.v1
Subject:
Physical Sciences,
Atomic And Molecular Physics
Keywords:
Biofilms; virtual screening; molecular dynamics; natural products; binding energy; trans-Aconitic acid; hit-to-lead
Online: 3 September 2020 (03:53:16 CEST)
REVIEW
|
doi:10.20944/preprints202008.0685.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
vitamin D; muscle; parathyroid hormone; vitamin D-binding protein
Online: 30 August 2020 (18:31:44 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0470.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Amyotrophic Lateral Sclerosis (ALS); Fronto-Temporal-Lobar-Dementia; Tauopathies; synaptic plasticity; long-term potentiation; spatial learning; inositol signaling; neurexin; K-homology RNA-binding domain; Fragile-X-associated Tremor-Ataxia syndrome
Online: 21 August 2020 (04:39:19 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0639.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
chromatin immunoprecipitation with massively parallel sequencing, transcription factors binding sites prediction; cooperative binding of transcription factors; composite elements; motifs conservation; classification of transcription factors; ETS transcription factor family; direct binding of transcription factors; overlap of motifs
Online: 20 August 2020 (13:43:09 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0318.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
nicotinic acetylcholine receptors; three-finger toxins; acetylcholine binding protein; protein – protein docking; computational modeling
Online: 14 August 2020 (09:57:35 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0150.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
chaperone function; heat-shock proteins; lipid binding; phosphatidylserine; protein refolding
Online: 29 July 2020 (12:18:02 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0363.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Ebola virus; filovirus; lipid binding; matrix protein; VP24
Online: 17 July 2020 (06:00:08 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0359.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
food allergens; egg allergy; milk allergy; fish allergy; amyloids; IgE-binding
Online: 16 July 2020 (13:31:23 CEST)
REVIEW
|
doi:10.20944/preprints202007.0314.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
hepatic fibrosis; Mac-2 binding protein glycated isomer; apoptosis inhibitor of macrophage; patatin-like phospholipase domain-containing protein 3; α-fetoprotein; PIVKA-II
Online: 14 July 2020 (13:55:16 CEST)
REVIEW
|
doi:10.20944/preprints202006.0213.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RORγ; plasticity; druggability; orthosteric binding pocket; allosteric binding pocket
Online: 10 July 2020 (01:50:44 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202006.0206.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
serine protease; interferon; ribonucleoproteins; RNA binding proteins; SERPIN; A1AT; hemostasis rebalancing
Online: 17 June 2020 (03:20:54 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0227.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
meta-analysis; transcription factor; binding site; genomics; transcriptomics; chilling stress; CBF; DREB; CAMTA
Online: 13 May 2020 (15:17:16 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202005.0192.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
SARS-CoV2; corona virus; affinity proteomics; glycoproteins; glycoprotein-binding domains
Online: 11 May 2020 (10:24:43 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0522.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
RNA Nucleotides; Uracil; Intermolecular Binding; Cyclic Compounds
Online: 30 April 2020 (08:58:21 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202004.0476.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
androgen insensitivity syndrome; androgen receptor; ligand binding domain; pathogenic mutation; bioinformatics
Online: 27 April 2020 (03:59:38 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0264.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RBFOX3; HTERT; gastric cancer; promoter-binding protein; cancer biomarker
Online: 16 April 2020 (08:17:44 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0296.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
retinol binding protein 4 receptor 2; RBP4; Rbpr2; STRA6; all-trans retinol transport; photoreceptor cell; vision; retinoids; zebrafish
Online: 19 March 2020 (03:16:19 CET)
REVIEW
|
doi:10.20944/preprints202003.0285.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
HIF-1α; NQO1; hypoxia; angiogenesis; cancer; protein:protein interactions; ligand binding; proteasomal degradation
Online: 18 March 2020 (08:45:33 CET)
COMMUNICATION
|
doi:10.20944/preprints202003.0125.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
2019-nCoV; Darunavir; ACE-2; Receptor Binding Domain; Metastable Conformation; FDA database
Online: 7 March 2020 (16:28:05 CET)
BRIEF REPORT
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
heterologous vaccine; receptor-binding domain; subunit vaccine; coronavirus; COVID-19; SARS; SARS-CoV-2
Online: 4 March 2020 (05:19:16 CET)
ARTICLE
|
doi:10.20944/preprints202002.0467.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Ebola virus; filovirus; lipid binding; Marburg virus; membrane trafficking; virus assembly; VP40
Online: 29 February 2020 (13:12:20 CET)
ARTICLE
|
doi:10.20944/preprints202002.0234.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
adeno-associated virus; protein sequence analysis; overlapping genes; amino acid depletion; cysteine depletion; tyrosine depletion; capsid design; membrane-binding amphipathic helix
Online: 17 February 2020 (02:42:39 CET)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Insecta; Chemosensory proteins; Odorant binding proteins; Peptide mutation; Cell evolution; Abiogenesis
Online: 30 January 2020 (03:02:21 CET)
ARTICLE
|
doi:10.20944/preprints202001.0279.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
NS3 inhibitors; allosteric inhibitors; NS4A; peptidomimetics; imidazole; hepatitis C virus; molecular dynamics; Flaviviridae; DSLS; binding assay
Online: 24 January 2020 (11:11:46 CET)
ARTICLE
|
doi:10.20944/preprints202001.0219.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
protruding features; spherical virus; point arrays; surface modifications; VLP; drug delivery; icosahedral; nanomedicine; ligand binding
Online: 20 January 2020 (06:59:09 CET)
ARTICLE
|
doi:10.20944/preprints202001.0062.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
C2 domain; E3 ubiquitin ligase; lipid binding; phosphoinositide; plasma membrane; smurf1; ubiquitin
Online: 8 January 2020 (04:34:28 CET)
REVIEW
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
calmodulin; calmodulin binding proteins; calmodulin binding motifs; calcium signalling; EF hands; heart arrythmia; neurodegeneration; Dictyostelium discoideum
Online: 15 December 2019 (15:44:35 CET)
ARTICLE
|
doi:10.20944/preprints201911.0398.v2
Subject:
Physical Sciences,
Nuclear And High Energy Physics
Keywords:
large nuclear gravity; strong coupling constant; nuclear stability; nuclear binding energy; free nucleons; active nucleons; magic numbers; up and down Quark clusters
Online: 4 December 2019 (04:48:31 CET)
ARTICLE
|
doi:10.20944/preprints201911.0255.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
arabidopsis thaliana; floral development; flower morphology; ds transposon; classical/sequencing-based mapping; LEAFY; DNA-binding
Online: 22 November 2019 (06:39:06 CET)
ARTICLE
|
doi:10.20944/preprints201911.0134.v1
Subject:
Physical Sciences,
Nuclear And High Energy Physics
Keywords:
four gravitational constants; compound reduced Planck’s constant; nuclear elementary charge; strong coupling constant; nuclear stability and binding energy; quark masses
Online: 12 November 2019 (16:53:07 CET)
ARTICLE
|
doi:10.20944/preprints201911.0131.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
epitope; monoclonal antibodies; open reading frame 3 protein; apoptosis; p53; porcine circovirus type 2; thimerosal; interfere; antibody binding; lymphocyte
Online: 12 November 2019 (16:20:27 CET)
ARTICLE
|
doi:10.20944/preprints201911.0061.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
rett syndrome; intrinsically disordered region; phylogenetic profile analysis; post-transcriptional modification; methyl-cpg-binding protein 2; cyclin-dependent kinase-like 5; forkhead box protein g1
Online: 6 November 2019 (10:58:54 CET)
ARTICLE
|
doi:10.20944/preprints201910.0297.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
polyelectrolytes; charge regulation; charge fluctuations; weak polyelectrolyte; annealed polyelectrolyte; monte carlo simulation; semi-grand canonical ensemble; binding equilibria; conformational equilibria; constant ph ensamble; stretching; scaling law
Online: 27 October 2019 (10:01:16 CET)
ARTICLE
|
doi:10.20944/preprints201910.0281.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
protein structural dynamics; NQO1; ligand binding; protein stability; allostery; protein degradation
Online: 24 October 2019 (15:41:46 CEST)
ARTICLE
|
doi:10.20944/preprints201910.0161.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Enterovirus 71; EV71; EV71 non-structural protein 2B; interleukin enhancer binding factor 2; ILF2; virus infection; virus replication
Online: 15 October 2019 (05:37:34 CEST)