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Preprint ARTICLE | doi:10.20944/preprints202301.0010.v1

Usefulness of Systemic Venous Ultrasound Protocols in the Prognosis of Heart Failure Patients: Results from a Prospective Multicentric Study

Marta Torres-Arrese, Arantzazu Mata-Martínez, Davide Luordo-Tedesco, Gonzalo García-Casasola, Rodrigo Alonso-González, Esther Montero-Hernández, Marta Cobo-Marcos, Beatriz Sánchez-Sauce, Valentín Cuervas-mons, Yale Tung-Chen

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: point-of-care ultrasound; Doppler ultrasound; VExUS; venous excess ultrasonography; acute heart failure; portal vein; hepatic vein; intrarenal vein; inferior vena cava

Online: 3 January 2023 (07:33:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0556.v1

Design and Implementation of an Environmental Planning Analysis Platform based on the "Three Lines One Permit"

Xuya Zhang, Kuikui Yuan, Hongdi Lv, Lei Yu, Changbo Qin

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Three Lines One Permit; web-based interactive analysis; online environmental planning analysis platform; EIA approval; Web-GIS; geospatial data; Guangzhou

Online: 29 December 2022 (08:56:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0524.v1

Spectral Matching of Three-Component Seismic Ground Accelerations for Critical Structures

Sindur Mangkoesoebroto, Adi Yasa, Ediansjah Zulkifli

Subject: Engineering, Civil Engineering Keywords: spectral matching; three components; component scales; phase angle; critical structures

Online: 28 December 2022 (02:25:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0440.v1

Implementation of Antimicrobial Stewardship in a District Hospital in the Ashanti Region of Ghana Using a Health Partnership Model

Obed Kwabena Offe Amponsah, Aaron J. Courtenay, Ahmed Abuelhana, Nana Kwame Ayisi-Boateng, Douglas Anning Opoku, Lawrence Kobbina Blay, Nana Akua Abruquah, Annabella Bensusan Osafo, Charlotte Boachie Danquah, Phyllis Tawiah, Mercy Naa Aduele Opare-Addo, Alex Owusu-Ofori, Kwame Ohene Buabeng

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: Antimicrobial stewardship; Point prevalence survey; Antimicrobial resistance; Ghana; CwPAMS; Antibiotic use; THET

Online: 23 December 2022 (03:53:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0356.v1

Longitudinal Registration of Chest CT Images With Radiation-Induced Lung Disease

Fan-Ya Lin, Ya-Jing Li, Chi-En Lee, Kuo-Lung Lor, Hao-Jen Wang, Yeun-Chung Chang, Chung-Ming Chen

Subject: Medicine And Pharmacology, Other Keywords: Component Structure Coherence Point Drift; parenchyma change induced by radiotherapy; computed tomography; feature point sampling; regional vascular point matching; longitudinal registration

Online: 20 December 2022 (07:28:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202211.0566.v1

Determine the Exact Value of the Square Root of 2

Qing Li

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: the square root of 2 ,the decimal point; jump; change in direction; the infinitely great

Online: 30 November 2022 (06:18:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202211.0508.v1

Real-Time Interpolated Rendering of Terrain Point Cloud Data

Jaka Kordež, Matija Marolt, Ciril Bohak

Subject: Computer Science And Mathematics, Software Keywords: point clouds; interpolation methods; terrain rendering

Online: 28 November 2022 (09:56:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints202209.0447.v2

Seismic Signatures and Site Characterization of an Intermittent Stream in Dry and Flood Conditions: An Implication for Soil Losses and Landslide Triggering

Yawar Hussain, Helena Seivane, Gao Qiangshan, Susanne Maciel, Omar Hamza, Rogério Uagoda, Welitom Rodrigues Borges

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: change-point analysis; weak spots; spectral analysis; ambient noise RMS; georadar attribute

Online: 16 November 2022 (02:35:38 CET)

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Identifying ambient noise-based (ANb) signatures of streams can help in the estimation of their erosive potential (EP) that promotes reverie landslides and soil losses in the fluvial valleys. This is particularly imperative on flooding or rainy days, leading to stronger erosion-prone conditions (colluvium and boulders) of the valley beds inferred from georadar attribute analysis. Developing such research direction can benefit the local communities, as is the case with the Cerrado region of Brazil, where these phenomena have high destructive potential with social, economic, and climatic implications. For the present study, a seasonal stream in the Federal District of Brazil was investigated by ANb monitoring supported by Ground Penetration Radar (GPR) for site characterization. The ANb monitoring was conducted (at a safe distance) with a seismometer over several durations of dry and rainy conditions. The power spectral density (PSDs) was computed as a function of several variables, including weather conditions (rainfall, wind speed, and pressure), time-frequency spectrograms, and ambient noise displacement root mean square (RMS). This analysis also considered the single station horizontal-to-vertical spectral ratio (HVSR), where rain, wind, pressure, river flow and anthropogenic signatures were evident (at selective frequency ranges). Multi-peaks that emerged on the HVSR curve were further analyzed to identify amplitude and frequency changes, and the three peaks shift on average to a lower position during the rainy period. The GPR amplitude and waveform variation features were attributed to the stratigraphy (i.e., the boundary between valid and invalid regions and coherence value) of the floodplain and regions susceptible to erosion (erosion-prone lithological spots). This approach provides the basis for non-destructive monitoring tools enabling the detection of 'seismic signatures' and weak spots of the fluvial channels for improving environmental management.

Preprint ARTICLE | doi:10.20944/preprints202211.0285.v1

Inter-rater Variability in the Evaluation of Lung Ultrasound on Videos Acquired from COVID-19 Patients

Joaquin L. Herraiz, Clara Freijo, Jorge Camacho, Mario Muñoz, Ricardo González, Rafael Alonso-Roca, Jorge Álvarez-Troncoso, Luis Matías Beltrán-Romero, Máximo Bernabeu-Wittel, Rafael Blancas, Antonio Calvo-Cebrián, Ricardo Campo-Linares, Jaldún Chehayeb-Morán, Jose Chorda-Ribelles, Samuel García-Rubio, Gonzalo García-de-Casasola, Adriana Gil-Rodrigo, César Henríquez-Camacho, Alba Hernandez-Píriz, Carlos Hernandez-Quiles, Rafael Llamas-Fuentes, Davide Luordo, Raquel Marín-Baselga, María Cristina Martínez-Díaz, María Mateos-González, Manuel Mendez-Bailon, Francisco Miralles-Aguiar, Ramón Nogue, Marta Nogué, Borja Ortiz de Urbina-Antia, Alberto Ángel Oviedo-García, José M. Porcel, Santiago Rodriguez, Diego Aníbal Rodríguez-Serrano, Talía Sainz, Ignacio Manuel Sánchez-Barrancos, Marta Torres-Arrese, Juan Torres-Macho, Ángela Trueba-Vicente, Tomas Villen-Villegas, Juan José Zafra-Sánchez, Yale Tung-Chen

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: Coronavirus disease 2019; interobserver agreement; interrater reliability; lung ultrasound; point-of-care ultrasound; reliability; severe acute respiratory syndrome; ultrasound

Online: 15 November 2022 (09:57:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202211.0034.v1

SAUSA: Securing Access, Usage, and Storage of 3D Point Clouds Data by a Blockchain-based Authentication Network

Ronghua Xu, Yu Chen, Genshe Chen, Erik Blasch

Subject: Computer Science And Mathematics, Information Systems Keywords: Blockchain; Smart Contract; Point Cloud; Security; Privacy Preservation; Software-Defined Network (SND); Big Data; Assurance; Resilience.

Online: 2 November 2022 (02:18:50 CET)

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The rapid development of three-dimensional (3D) acquisition technology based on 3D sensors provides a large volume of data, which is often represented in the form of point clouds. Point cloud representation can preserve the original geometric information along with associated attributes in a 3D space. Therefore, it has been widely adopted in many scene-understanding-related applications such as virtual reality (VR) and autonomous driving. However, the massive amount of point cloud data aggregated from distributed 3D sensors also poses challenges for secure data collection, management, storage, and sharing. Thanks to the characteristics of decentralization and security nature, Blockchain has a great potential to improve point cloud services and enhance security and privacy preservation. Inspired by the rationales behind Software Defined Network (SDN) technology, this paper envisions SAUSA, a blockchain-based authentication network that is capable of recording, tracking, and auditing the access, usage, and storage of 3D point cloud data sets in their life-cycle in a decentralized manner. SAUSA adopts an SDN-enabled point cloud service architecture which allows for efficient data processing and delivery to satisfy diverse Quality-of-Service (QoS) requirements. A blockchain-based authentication framework is proposed to ensure security and privacy preservation in point cloud data acquisition, storage, and analytics. Leveraging smart contracts for digitizing access control policies and point cloud data on the blockchain, data owners have full control of their 3D sensors and point clouds. In addition, anyone can verify the authenticity and integrity of point clouds in use without relying on a third party. Moreover, SAUSA integrates a decentralized storage platform to store encrypted point clouds while recording references of raw data on the distributed ledger. Such a hybrid on-chain and off-chain storage strategy not only improves robustness and availability but also ensures privacy preservation for sensitive information in point cloud applications. A proof-of-concept prototype is implemented and tested on a physical network. The experimental evaluation validates the feasibility and effectiveness of the proposed SAUSA solution.

Preprint ARTICLE | doi:10.20944/preprints202210.0446.v1

Point-of-Care Testing, Spatial Care Paths, and Enhanced Standards of Care – Preparing Island Communities for Global Warming and Rising Oceans

Gerald Kost, Anna Fuzery, Louie Caratao, Samantha Tinsay, Amanullah Zadran, Adrian Ybanez

Subject: Public Health And Healthcare, Nursing Keywords: acute myocardial infarction; coronavirus disease 2019 (COVID-19); island communities; point-of-care testing; spatial care paths

Online: 28 October 2022 (09:30:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0358.v1

A Modified single frequency PPP method for the Positioning and Time transfer with BDS-3

Mingjun OuYang, Xiangwei Zhu, Junzhi Li, Liu Yang

Subject: Environmental And Earth Sciences, Space And Planetary Science Keywords: BDS-3; Time transfer; Precise point positioning; Single frequency; Group and Phase Ionospheric Correction (GRAPHIC)

Online: 24 October 2022 (10:01:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0349.v1

Using Various Analysis Center Products to Assess the Time-Frequency Transfer Performance of GPS/Galileo/BDS PPPAR Methods

Mingjun OuYang, Xiangwei Zhu, Ruite Yi, Daqian Lyu

Subject: Environmental And Earth Sciences, Space And Planetary Science Keywords: Time Frequency Transfer; Precise Point Positioning; Ambiguity Resolution (AR); Analysis Center (AC)

Online: 24 October 2022 (05:33:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0314.v1

Evaluation of Different Cannulation Strategies for Aortic Arch Surgery Using a Cardiovascular Numerical Simulator

Beatrice De Lazzari, Massimo Capoccia, Roberto Badagliacca, Claudio De Lazzari

Subject: Medicine And Pharmacology, Surgery Keywords: Aortic surgery; Aortic arch; Three-way cannulation approach; Carotid artery perfusion; Pressure-volume loop; Lumped parameter model; Software simulation; Cardiovascular modelling.; CARDIOSIM

Online: 20 October 2022 (14:19:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0260.v1

Induction Generator with Direct Control and a Limited Number of Measurements on the Side of the Converter Connected to the Power Grid

Andrzej Kasprowicz, Ryszard Strzelecki

Subject: Engineering, Electrical And Electronic Engineering Keywords: induction generator; Direct Field Oriented Control (DFOC), three-level inverter; sinusoidal pulse width modulator (SPWM), maximum power point tracking (MPPT)

Online: 18 October 2022 (10:33:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0143.v1

A Composite Exponential Reaching Law based SMC with Rotating Sliding Surface Selection Mechanism for Two Level Three Phase VSI in Vehicle to Load Applications

Faheem Haroon, Muhammad Aamir, Assad Waqar, Saeed Mian Qaisar, Syed Umaid Ali, Abdulaziz Turki Almaktoom

Subject: Engineering, Control And Systems Engineering Keywords: Sliding Mode Control; Three phase Voltage Source Inverter; Reaching Law; Chattering; Sliding Surface.

Online: 11 October 2022 (05:39:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0038.v1

Minimalised Three-Dimensional Human Midbrain In Vitro Model for Neurotoxicity Evaluation of DYRK1 Inhibitors

Xiao Wan, Vincent Fagan, Paul Brennan, Daniel Ebner

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: three-dimensional in vitro model; DYRK1; human midbrain; neural progenitor cells

Online: 5 October 2022 (11:29:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202209.0109.v1

Moving Object Detection Based on a Combination of Kalman Filter and Median Filtering

Diana Kalita, Pavel Lyakhov

Subject: Computer Science And Mathematics, Information Systems Keywords: Kalman filter; median filter; impulse noise; estimate prediction; object distance determination; lidar; value calibration; point cloud.

Online: 7 September 2022 (10:20:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202209.0106.v1

Tightly Coupled Ultra-Wideband Phased-Array Implemented by Three-Dimensional Inkjet Printing Technique

Lei Han, Gang Wang, Lin Zhang, Weixu Jiang, Pengbing Zhao, Wei Tang, Tao Dang, Hongxing Zheng

Subject: Engineering, Electrical And Electronic Engineering Keywords: Ultra-wideband; conformal antenna array; coupled tightly; three-dimensional printing technique; fused deposition modelling; microdroplet injection molding

Online: 7 September 2022 (08:15:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0477.v1

LiDAR and UAV SfM-MVS of Merapi Volcanic Dome And Crater Rim Change from 2012 to 2014

Christopher Gomez, Franck Lavigne, Noviyanti Listyaningrum, Sandy Budi Wibowo, Danang Sri Hadmoko, Wiwit Suryanto, Herlan Darmawan, Balazs Bradak, Rikuto Daikai, Sunardi Sunardi, Yudo Prasetyo, Annisa Joviani Astari, Lukman Lukman, Idea Wening Nurani, Moh. Dede, Indranova Suhendro

Subject: Environmental And Earth Sciences, Geochemistry And Petrology Keywords: Merapi Volcano; Indonesia; Natural Hazards; Disaster Risk and Point-cloud technology

Online: 29 August 2022 (08:34:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0426.v1

Multi-View and Shift Rasterization Algorithm (MVSR) for Effective Identification of Ground in Dense Point Clouds

Martin Štroner, Rudolf Urban, Lenka Línková

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: Point cloud; Ground filtering; Classification

Online: 25 August 2022 (07:22:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0060.v1

Bending Analysis of Integrated Multilayer Corrugated Sandwich Panel Based on 3D Printing

Wen Dang, Xuanting Liu, Bohua Sun

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: multi-layer core corrugated sandwich panel; three-point bending; 3D printing; core shape; number of core layers

Online: 2 August 2022 (10:00:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0440.v1

The IASI Water Deficit Index to Monitor the Vegetation Stress and the Early Drying in Summer Because of Heatwaves: an Application to Southern Italy

Guido Masiello, Francesco Ripullone, Italia De Feis, Angelo Rita, Luigi Saulino, Pamela Pasquariello, Angela Cersosimo, Sara Venafra, Carmine Serio

Subject: Environmental And Earth Sciences, Environmental Science Keywords: climate change; drought; water deficit index; infrared observations; satellite; remote sensing; surface temperature; air temperature; humidity; dew point temperature

Online: 29 July 2022 (02:36:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0386.v1

On Improved PSO and Neural Network P&O Methods for PV System under Shading and Various Atmospheric Conditions

Wafa Hayder, Dezso Sera, Emanuele Ogliari, Abderezak Lashab

Subject: Engineering, Control And Systems Engineering Keywords: Maximum Power Point Tracking (MPPT); Improved Particle Swarm Optimization (IPSO); photo-voltaic (PV); Neural Network and Perturb & Observe method (NN-P&O)

Online: 26 July 2022 (05:41:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0339.v1

Optimizing Public Health Preparedness for Highly Infectious Diseases in Central Vietnam

Amanullah Zadran, An V.D. Ho, Layma Zadran, Irene J Ventura Curiel, Tang-Tung Pham, Duong Thi Bich Thuan, Gerald J Kost

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Infectious disease testing; public health preparedness; point-of-care testing (POCT); molecular diagnostics; therapeutic turnaround time (TTAT); acute medical challenges; geographic information systems; antimicrobial stewardship

Online: 22 July 2022 (13:13:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0269.v1

Analytical Derivations of Critical Temperatures in Every Type of Fe-Based Superconductors Based on Two Electrons’ Rotational Model

Shinichi Ishiguri

Subject: Physical Sciences, Condensed Matter Physics Keywords: Fe-based superconductor; critical temperature; transition temperature; attractive Lorentz force; Tc-dome diagram; structure transition; quantum critical point

Online: 18 July 2022 (11:03:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0049.v1

Reconstructing the Three-Dimensional Structure of Loop Current Rings from Satellite Altimetry and in situ Data using the Gravest Empirical Modes Method

Thomas Meunier, Paula Perez Brunius, Amy Bower

Subject: Environmental And Earth Sciences, Oceanography Keywords: three-dimensional eddy reconstruction; Loop Current rings; Gulf of Mexico; Gravest Empirical Modes

Online: 4 July 2022 (10:05:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0368.v1

A 3DCNN-LSTM Multi-Class Temporal Segmentation for Hand Gesture Recognition

Letizia Gionfrida, Wan M.R. Rusli, Angela E. Kedgley, Anil A. Bharath

Subject: Computer Science And Mathematics, Computer Science Keywords: hand gesture classification; transfer learning; three-dimensional convolutional; LSTM network

Online: 27 June 2022 (13:36:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0342.v1

Uniform Test on the Mixture Simplex Region

Haiqing Zhao, Guanghui Li, Junpeng Li

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: mixture experiments; lattice point sets; uniform designs

Online: 27 June 2022 (03:09:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0300.v1

Multi-View and Shift Rasterization Algorithm (MVSR) for Effective Identification of Ground in Dense Point Clouds

Martin Štroner, Rudolf Urban, Lenka Línková

Subject: Engineering, Control And Systems Engineering Keywords: Point cloud; Ground filtering; Classification

Online: 22 June 2022 (03:37:45 CEST)

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With the ever-increasing popularity of unmanned aerial vehicles and other platforms providing dense point clouds, universal filters for accurate identification of ground points in such dense clouds are needed. Many filters have been proposed and are widely used, usually based on the determination of an original surface approximation and subsequent identification of points within a predefined distance from such surface. In this paper, we present a new filter. This Multi-view and shift rasterization algorithm (MVSR) is based on an entirely different principle, i.e., on the identification of just the lowest points in individual grid cells, shifting the grid along both planar axis and subsequent tilting of the entire grid – after each of these steps, one lowest point per cell is detected. The principle is presented in detail and compared both visually and numerically to other commonly used ground filters (PMF, SMRF, CSF, ATIN) on three sites with different ruggedness and vegetation density. Visually, the MVSR filter showed the smoothest and thinnest ground profiles, with ATIN the only filter performing comparably (although the profiles were somewhat thicker and not as complete as MVSR-acquired ground). The same was confirmed when comparing ground filtered by other filters with the MVSR-based surface. The goodness of fit with the original cloud is demonstrated by the root mean square deviations (RMSD) of the points from the original cloud found below the MVSR-generated surface (ranging, depending on site, between 0.6-2.5 cm). ATIN again performed closest to MVSR, with RMSDs of ground filtered points found above MVSR-based surface at individual sites ranging between 4.5-7.4 cm. The remaining filters performed comparable in the simplest flat area but poorly in rugged and much-vegetated sites, with RMSDs above the MVSR surface ranging at such sites from 21 to 95 cm. In conclusion, the novel filter presented in this paper performed outstandingly at all sites, identifying the ground points with great accuracy while filtering out the maximum of vegetation/above-ground points. The filter dilutes the cloud somewhat; in such dense point clouds, however, this can be perceived rather as a benefit than as a disadvantage.

Preprint ARTICLE | doi:10.20944/preprints202206.0023.v1

Innate Health: A Novel Examination of What Explains Well-being, Prosocial Behavior, and Aggression among Men Living in a UK Prison

Jeanne Catherine, Adriaan Denkers, Anita McGinty

Subject: Social Sciences, Psychology Keywords: well-being; innate health; positive psychology; mental health; three principles; self-control; pro-social behaviors; criminology; incarcerated men; prisoners; inmates

Online: 2 June 2022 (02:57:49 CEST)

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Preprint REVIEW | doi:10.20944/preprints202205.0399.v1

Non-Linear Reconstruction of Images from Patterns Generated by Deterministic or Random Optical Masks – Concepts and Review of Research

Daniel Smith, Shivasubramanian Gopinath, Francis Gracy Arockiaraj, Andra Naresh Kumar Reddy, Vinoth Balasubramani, Ravi Kumar, Nitin Dubey, Soon Hock Ng, Tomas Katkus, Shakina Jothi Selva, Dhanalakshmi Renganathan, Beaula Ruby Kamalam Manueldoss, Aravind Simon John Francis Rajeswary, Srinivasan Navaneethakrishnan, Stephen Rajkumar Inbanathan, Sandhra-Mirella Valdma, Praveen Periyasamy Angamuthu, Amudhavel Jayavel, Manoj Kumar, Rashid A Ganeev, Pierre J Magistretti, Christian Depeursinge, Saulius Juodkazis, Joseph Rosen, Vijayakumar Anand

Subject: Physical Sciences, Optics And Photonics Keywords: Holography; computational imaging; non-linear reconstruction; Fresnel incoherent correlation holography; coded aperture imaging; rotating point spread function; diffractive optics; scattering.

Online: 30 May 2022 (11:37:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0314.v1

The Coronavirus Disease 2019 Spatial Care Path: Home, Community, and Emergency Diagnostic Portals

Gerald J. Kost

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: Emergency Use Authorization; endemic; false omission; false omission rate; home testing; point-of-care testing (POCT); positive predictive value geometric mean-squared; prevalence boundary; recursive protocol; tier; visual logistics

Online: 30 April 2022 (08:42:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0203.v1

The Nonlinear Analysis Related to Schauder Fixed Points, Best Approximation, Birkhoff-Kellogg Problems and Principle of Leray-Schauder Alternatives in p-Vector Spaces

George X. Yuan

Subject: Computer Science And Mathematics, Analysis Keywords: nonlinear analysis; best approximation; Birkhoff-Kellogg theorem; schauder conjecture; fixed point theorem; nonlinear alternative; Leray-Schauder alternative; p-convex; p-inward and p-outward set; p-vector space

Online: 21 April 2022 (10:22:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0375.v1

Rapid Detection of Anti-SARS-CoV-2 Antibodies With a Screen-Printed Electrode Modified With a Spike Glycoprotein Epitope

Wiilson Ameku, David Provance, Carlos Morel, Salvatore De-Simone

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; COVID-19; spike glycoprotein; epitope; electrochemical biosensor; point of care; immunological diagnostic

Online: 29 March 2022 (08:39:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0278.v1

Usefulness of Multi-Organ Point-Of-Care Ultrasound as a Complement to the Decision-Making Process in Internal Medicine

Irene Casado-López, Yale Tung-Chen, Marta Torres-Arrese, Davide Luordo-Tedesco, Arantzazu Mata-Martínez, Jose Manuel Casas-Rojo, Esther Montero-Hernández, Gonzalo García De Casasola-Sánchez

Subject: Medicine And Pharmacology, Internal Medicine Keywords: point-of-care ultrasound; internal medicine; lung ultrasound; echocardiography; abdominal ultrasound

Online: 21 March 2022 (08:39:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202112.0340.v2

Spin g Factors and Neutrino Magnetic Moment of Elementary Fermions

Jae-Kwang Hwang

Subject: Physical Sciences, Particle And Field Physics Keywords: Anomalous spin g factor; Lepton charge (LC); Neutrino magnetic moment; Weak force decay; EC and LC partial masses; Three-dimensional quantized space model (TQSM)

Online: 1 March 2022 (11:25:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0319.v1

Analyses and the cause of corrosion and materials loss at the base of a three-phase separator in petroleum-based processing

Han Ding, Houbu Li, Dongtao Qi, Zhao Zhang, Guoquan Qi, Bin Wei, Xuehua Cai

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: Three-phase separator; Perforation; Corrosion; Galvanic

Online: 25 February 2022 (01:46:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0277.v2

Research on Mechanical Braking Model of Cows Knee Joint

Meng Liu, Kexin Meng, Shuli Mei, Ruyi Xing

Subject: Physical Sciences, Mathematical Physics Keywords: Dairy cow; Lyapunov exponent; bio-mechanical model; Nonlinear dynamics; gait; Weight scale; Three-link model; Fractals

Online: 24 February 2022 (09:57:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0126.v1

Roach Infestation Optimization MPPT Algorithm for Solar Photovoltaic System

Chittaranjan Pradhan, Nicholas Kakra Ntiakoh, Rajnish Kaur Calay

Subject: Engineering, Electrical And Electronic Engineering Keywords: DC-DC Boost converter; Maximum power point tracking (MPPT); Partial shading condition (PSC); Particle swam optimization (PSO); Roach infestation optimization (RIO); Solar photovoltaic system

Online: 9 February 2022 (07:59:07 CET)

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Preprint BRIEF REPORT | doi:10.20944/preprints202202.0045.v1

Functional Near-infrared Spectroscopy Of Prefrontal Cortex During Memory Encoding And Recall In Elderly With Type 2 Diabetes Mellitus

Fei Zhao, Machiko Tomita, Anirban Dutta

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: fNIRS; diabetes; brain imaging; point of care

Online: 3 February 2022 (10:10:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202112.0489.v1

Nighttime Sleep Awakening Frequency and Its Consistency Predict Future Academic Performance in College Students

Ghee Wee Ho, Zhenzhi Yang, Linna Xing, Ken Kang-Too Tsang, Huada Daniel Ruan, Yu Li

Subject: Social Sciences, Psychology Keywords: sleep; academic performance; grade point average; college students; wearable device; longitudinal; nighttime sleep awakening

Online: 30 December 2021 (13:45:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202111.0270.v2

Improve the Three-phase Unbalance Rate of Railway System Under 2% By Three Kinds of Special Transformer Wiring

Chien-Hsu Chen, Chin E. Lin

Subject: Engineering, Electrical And Electronic Engineering Keywords: three-phase unbalance rate (TPUR); negative phase sequence unbalance rate (NPSUR); special transformer wiring (STW); Railway System Transport Cable (RSTC); Traction Supply Substation (TSS)

Online: 14 December 2021 (15:26:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202112.0192.v1

Using Enhanced Sparrow Search Algorithm-Deep Extreme Learning Machine Model to Forecast End-Point Phosphorus Content of BOF

Lingxiang Quan, Ailian Li, Guimei Cui, Shaofeng Xie

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: End-point phosphorus content; Deep extreme learning machine; Sparrow search algorithm; Trigonometric substitution; Cauchy mutation

Online: 10 December 2021 (15:04:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202112.0113.v1

Usefulness of Serial Multiorgan Point-of-Care Ultrasound in Acute Heart Failure: Results from a Prospective Observational Cohort

Marta Torres-Arrese, Gonzalo García de Casasola-Sánchez, Manuel Méndez-Bailón, Esther Montero-Hernández, Marta Cobo-Marcos, Mercedes Rivas-Lasarte, Luis Caurecel-Díaz, Pablo Rodríguez-Fuertes, Tomas Villén-Villegas, Yale Tung-Chen

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: acute heart failure (AHF); venous congestion; Point-of-Care Ultrasound (POCUS); VExUS (venous excess ultrasonography score).

Online: 7 December 2021 (23:46:59 CET)

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Background and Objectives: Acute Heart Failure (AHF) is a common disease and a cause of high morbidity and mortality, constituting a major health problem. The main purpose of this study was to determine the impact of multiorgan ultrasound in identifying the pulmonary hypertension (PH) in patients admitted due to AHF, predict the evolution of the disease during hospitalization and identify areas of improvement in the care of patients with AHF. Materials and Methods: Patients were evaluated with a standard exam of lung ultrasound, echocardiography, inferior vena cava (IVC) and femoral, renal, hepatic, portal venous Doppler flow patterns at admission and on the day of discharge. Results: Thirty patients were enrolled during November 2021. The mean age was seventy-nine years (Standard Deviation – SD 13,4). Seven patients (23.3%) had a renal function worsening. Regarding ultrasound findings, venous excess ultrasonography score (VExUS) score was calculated at admission and at discharge, surprisingly remaining unchanged or even worsened in most of them (21 patients, 70.0%). The area under the curve for the Lung Score was 83.9% (p = 0.008), obtaining a cutoff value of 10 that showed a sensitivity of 82.6% and a specificity of 71.4% in the identification of intermediate and high PH. It was possible to monitor significant changes between both exams on the lung score (p <0.001), hepatic vein Doppler (p <0.001), portal vein Doppler (p = 0.030), intra-renal vein Doppler (p = 0.025) and VExUS score (p = 0.023), remaining similar the femoral vein Doppler (p = 0.177) and IVC (p = 0.132). Conclusions: Our study results suggest that performing serial multiorgan Point-of-Care ultrasound can help us to better identify high and intermediate probability of PH patients with AHF. Currently proposed multi-organ, venous Doppler scanning protocols, such as the VExUS score, should be further studied in different populations before expanding its use in AHF patients.

Preprint ARTICLE | doi:10.20944/preprints202112.0044.v1

Linear Quadratic Regulator and Fuzzy Control for Grid-Connected Photovoltaic Systems

Azamat Mukhatov, Nguyen Gia Minh Thao, Ton Duc Do

Subject: Engineering, Electrical And Electronic Engineering Keywords: fuzzy control; grid-connected; incremental conductance algorithm; linear quadratic regulator; maximum power point tracking; photovoltaic system

Online: 3 December 2021 (09:49:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202112.0032.v1

Characterization of Cardiopulmonary Interactions and Exploring Their Prognostic Value in Acute Bronchiolitis: A Prospective Cardiopulmonary Ultrasound Study

Moises Rodriguez-Gonzalez, Patricia Rodriguez-Campoy, Lorena Estepa-Pedregosa, Ana Estalella-Mendoza, Ana Castellano-Martinez, Jose Carlos Flores-Gonzalez

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Acute bronchiolitis; Lung ultrasound; Echocardiography; Point of care ultrasonography; Cardi-opulmonary ultrasound; Cardiopulmonary interactions; Pulmonary hypertension; Myocardial strain; NT-proBNP

Online: 2 December 2021 (11:22:02 CET)

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We aimed to delineate cardiopulmonary interactions in acute bronchiolitis and to evaluate the capacity of a combined cardiopulmonary ultrasonography to predict the need for respiratory support. This was a prospective observational single-center study that includes infants < 12 month of age admitted to a hospital due to acute bronchiolitis. All the included patients under-went clinical, laboratory and cardiopulmonary ultrasonographic evaluation at the same time point within 24 hours of hospital admission. The existence of significant correlation between car-diac and respiratory parameters was the primary outcome. The association of different cardio-pulmonary variables with the need of respiratory support higher than O2, the length of stay hos-pitalization, the PICU stay, and the duration of respiratory support were a secondary outcome. We enrolled 112 infants (median age 1 (0.5-3) months; 62% males) hospitalized with acute bron-chiolitis. Increased values of the pulmonary variables (BROSJOD score, pCO2 and LUS) showed moderate correlations with NT-proBNP and all echocardiographic parameters indicative of pulmonary hypertension and myocardial dysfunction. Up to 36 (32%) infants required respira-tory support during the hospitalization. This group presented with higher lung ultrasound score (p<0.001), and increased values of Tei index (p<0.001) and pulmonary artery pressures (p<0.001). All the analyzed respiratory and cardiac variables showed moderate to strong correlations with the LOS hospitalization and the time of respiratory support. Lung ultrasound and echocardiog-raphy showed a moderate to strong predictive accuracy for the need of respiratory support in the ROC analysis, with AUC varying from 0.74 to 0.87. Conclusion: Those cases of bronchiolitis with a worse pulmonary status presented with a more impaired cardiac status. Cardiopulmonary ul-trasonography could be a good strategy to easily identify high-risk population for a complicated acute bronchiolitis hospitalization.

Preprint ARTICLE | doi:10.20944/preprints202112.0002.v1

Performance Study of Absorption Tower and Adsorption Reactor to Eliminate Ammonia Gas as Pollutant

Ikha Rasti Julia Sari, Januar Arif Fatkhurrahman, Yose Andriani

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: ammonia; emission control; saturation point; absorption tower; adsorption reactor

Online: 1 December 2021 (10:22:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202111.0266.v1

Pan-Cancer Integrative Analysis of Whole-Genome De novo Somatic Point Mutations Reveals 17 Cancer Types

Amirreza Kazemi, Amin Ghareyazi, Kimia Hamidieh, Hamed Dashti, Maedeh Tahaei, Hamid Rabiee, Hamid Alinejad Rokny, Abdollah Dehzangi

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Pan-Cancer; somatic point mutations; cancer subtyping; biomarker discovery; driver genes; per-sonalized medicine; health data analytics

Online: 15 November 2021 (13:51:33 CET)

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The advent of high throughput sequencing has enabled researchers to systematically evaluate the genetic variations in cancer, resulting in identifying many cancer-associated genes. Although cancers in the same tissue are widely categorized in the same group, they demonstrate many differences concerning their mutational profiles. Hence there is no “silver bullet” for the treatment of a cancer type. This reveals the importance of developing a pipeline to identify cancer-associated genes accurately and re-classify patients with similar mutational profiles. Classification of cancer patients with similar mutational profiles may help discover subtypes of cancer patients who might benefit from specific treatment types. In this study, we propose a new machine learning pipeline to identify protein-coding genes mutated in a significant portion of samples to identify cancer subtypes. We applied our pipeline to 12270 samples collected from the International Cancer Genome Consortium (ICGC), covering 19 cancer types. Here we identified 17 different cancer subtypes. Comprehensive phenotypic and genotypic analysis indicates distinguishable properties, including unique cancer-related signaling pathways, in which, for most of them, targeted treatment options are currently available. This new subtyping approach offers a novel opportunity for cancer drug development based on the mutational profile of patients. We also comprehensive study the causes of mutations among samples in each subtype by mining the mutational signatures, which provides important insight into their active molecular mechanisms. Some of the pathways we identified in most subtypes, including the cell cycle and the Axon guidance pathways, are frequently observed in cancer disease. Interestingly, we also identified several mutated genes and different rates of mutation in multiple cancer subtypes. In addition, our study on “gene-motif” suggests the importance of considering both the context of the mutations and mutational processes in identifying cancer-associated genes. The source codes for our proposed clustering pipeline and analysis are publicly available at: https://github.com/bcb-sut/Pan-Cancer.

Preprint ARTICLE | doi:10.20944/preprints202111.0262.v1

Reduction of DC-drift in LiNbO3-based Electro-optical Modulator

Aleksei V. Sosunov, Roman S. Ponomarev, Anton A. Zhuravlev, Sergey S. Mushinsky, Mariana Kuneva

Subject: Physical Sciences, Optics And Photonics Keywords: lithium niobate; electro-optical modulator; DC-drift; operating point

Online: 15 November 2021 (13:37:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0272.v2

Urban Canyon in the CBD of Rio de Janeiro (Brazil): Thermal Profile of Avenida Rio Branco during Summer

Lidiane de Oliveira Lemos, Antonio Carlos Oscar-Júnior, Francisco Mendonça

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Urban climate; thermal field; three-dimensional structure; surface temperatures; heat islands; thermal inversion

Online: 15 November 2021 (12:30:33 CET)

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This study aims to evaluate the land surface temperature (LST) and the thermal characteristics of the Urban Canopy Layer (UCL) of the urban canyon in Avenida Rio Branco in the Central Business District (CBD) of Rio de Janeiro during summer. In order to conduct this evaluation, two methods were employed: 1) TIRS Landsat-8 sensor for data selection and processing (latest generation, 2011-2020); ; 2) field survey using nine sampling points — seven along two mobile transects, one fixed point, and one vertical measurement point, which required the use of a RPA (Remotely Piloted Aircraft). Three categories of analysis were established for the field survey based on the prevailing synoptic situations: stability, instability, and post-instability. The CBD is characterized by extensive areas with surface heat islands, in which temperatures were higher than 38.9°C; the areas with milder LSTs were Campo do Santana, Avenida Rio Branco, and one of the Mixed-Use Zones (Praça Mauá). With respect to Rio Branco Avenue, the LST niches of lowest elevation were derived through building shadowing; however, the orbital data diverged from the observation data of the ten field-study days. In situ data revealed that the characteristics urban morphology of Avenida Rio Branco is susceptible to the formation of heat islands, presenting heat islands of very strong magnitude (over 6.1°C) in atmospheric stability, strong magnitude (4.1-6.0°C) in atmospheric instability, and moderate magnitude (2.1°C-4.0°C) in post-atmospheric instability. Despite the synoptic situation, thermal cores were concentrated at 1 pm. The intersection between Avenida Rio Branco, Rua do Ouvidor, and Praça Mauá stored most of the solar energy received during the day due to the greater sky obstruction caused by the verticalization. Finally, vertical analysis demonstrated the formation of a thermal inversion on the night of the highest mean air temperature (29.5°C), probably, due to the roughness and number of buildings in the urban canyon.

Preprint REVIEW | doi:10.20944/preprints202111.0090.v2

Why and How to Use the Body’s Own Stem Cells for Regeneration in Musculoskeletal Disorders: A Primer

John Furia, Mark Lundeen, Jason Hurd, David Pearce, Christopher Alt, Eckhard Alt, Christoph Schmitz, Nicola Maffulli

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: adipose-derived regenerative cells; ADRCs; adipose-derived stem cells; ADSCs; bone regeneration, cartilage regeneration; efficacy; point of care treatment; stem cell; tendon healing without scar formation; tendon regeneration; vaPS cells

Online: 12 November 2021 (11:44:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202110.0249.v1

Predictive Model of ACC Speed to Enhance Engine Operating Conditions

Srikanth Kolachalama, Hafiz Malik

Subject: Engineering, Automotive Engineering Keywords: Adaptive Cruise Control; Driver behvaiour; Deep learning; Engine Operating Point; NARX

Online: 18 October 2021 (14:48:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202109.0424.v1

Microfluidic Lab-On-a-Chip based on UHF-Dielectrophoresis for Stemness Phenotype Characterization and Discrimination among Glioblastoma Cells

Elisa Lambert, Rémi Manczak, Elodie Barthout, Sofiane Saada, Elena Porcù, Francesca Maule, Barbara BESSETTE, Giampietro Viola, Luca Persano, Claire DALMAY, Fabrice Lalloué, Arnaud POTHIER

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: high frequency dielectrophoresis; glioblastoma cells; single cell manipulation; microfluidic point-of-care device; cancer stem cells

Online: 24 September 2021 (11:11:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202109.0269.v1

The System of Differential Equations Associated With Involutions

Farrukh Nuriddin ugli Dekhkonov

Subject: Computer Science And Mathematics, Mathematics Keywords: Involution; linear differential equation; fixed point; boundary value problem

Online: 15 September 2021 (15:19:50 CEST)

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Working Paper ARTICLE

Three-dimensional Transfer Functions of Interference Microscopes

Peter Lehmann, Sebastian Hagemeier, Tobias Pahl

Subject: Physical Sciences, Optics And Photonics Keywords: Interference microscopy; coherence scanning interferometry; three-dimensional transfer function

Online: 15 September 2021 (12:46:05 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202109.0225.v1

Designing an Efficient Self-Assembled Plasmonic Nanostructures from Spherical Shaped Nanoparticles

Vasanthan Devaraj, Jong-Min Lee, Ye-ji Kim, Hyuk Jeong, Jin-Woo Oh

Subject: Chemistry And Materials Science, Nanotechnology Keywords: Self-assembly; Metallic nanoparticles; Plasmonic modes; Simulations; Surface charge mappings; Full-width three-quarter maximum

Online: 14 September 2021 (08:45:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202109.0180.v1

MPCR-Net: Multiple Partial Point Clouds Registration Network Using a Global Template

Shijie Su, Chao Wang, Ke Chen, Jian Zhang, Yang Hui

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: point cloud registration; template point cloud; multiple partial point cloud; deep learning

Online: 10 September 2021 (10:26:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202109.0146.v1

Performance Analysis of Heterogeneous Networks in Presence of Deliberate Jammers Using Reverse Frequency Allocation

Muhammad Ihsan Ur Rehman, Muhammad Qasim, Abdul Wakeel, Mehmood Alam, Mir Yasir Umair

Subject: Engineering, Electrical And Electronic Engineering Keywords: Heterogeneous Cellular Networks; Deliberate Jamming; Inter-cell Interference; Independent Homogenous Poisson Point Process; Coverage Probability; Reverse Frequency Allocation

Online: 8 September 2021 (11:57:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202109.0112.v1

Contrasitive Learning for 3D Point Clouds Classification and Shape Completion

Danish Nazir, Muhammad Zeshan Afzal, Alain Pagani, Marcus Liwicki, Didier Stricker

Subject: Engineering, Marine Engineering Keywords: 3D point Cloud Classification, 3D point Cloud Shape Completion,Auto-Encoders, Contrastive Learning, Self-Supervised Learning

Online: 6 September 2021 (18:00:28 CEST)

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Working Paper REVIEW

C,C- and C,N-Chelated Organocopper Compounds

Liang Liu, Hui Chen, Zhenqiang Yang, Junnian Wei, Zhenfeng Xi

Subject: Chemistry And Materials Science, Inorganic And Nuclear Chemistry Keywords: organocopper; C,N-chelated; C,C-chelated; bidentate; butadienyl; intramolecular coordination; three center-two electron bonds; structure-reactivity relationship

Online: 2 September 2021 (12:01:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0415.v1

Intuitionistic Fuzzy Normed Prime Ideal and Some of Their Characteristics

Tekalign Regasa Ashale

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: Intuitionist Fuzzy Normed Ring; Intuitionist fuzzy normed Ideal; Intuitionist Fuzzy Normed Point; Fuzzy Normed Prime Idea

Online: 20 August 2021 (12:48:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0368.v1

An Investigation of Point Mutations Discovers Novel Genes and Their Corresponding Motifs in Pancreatic Cancer

Amin Ghareyazi, Amir Mohseni, Hamed Dashti, Abdollah Dehzangi, Hamid R. Rabiee, Hamid Alinejad-Rokny

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: pancreatic cancer; cancer subtype identification; somatic point mutations; genotype and phenotype characterization; therapeutic targets; personalized medicine

Online: 17 August 2021 (22:24:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0272.v1

Remaining Useful Life Prediction from 3D Scan Data with Genetically Optimized Convolutional Neural Networks

Giovanni Diraco, Pietro Siciliano, Alessandro Leone

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: Remaining Useful Life; Deep Neural Network; Convolutional Neural Network; Genetic Optimization; Neural Network Optimization; Support Vector Regression; Depth Maps; Normal Maps; 3D Point Clouds.

Online: 12 August 2021 (10:40:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0264.v1

Proposal Design of a Hybrid Solar PV-Wind-Battery Energy Storage for Standalone DC Microgrid Application

Mwaka Juma, Bakari M. M. Mwinyiwiwa, Consalva J. Msigwa, Aviti T. Mushi

Subject: Engineering, Electrical And Electronic Engineering Keywords: solar photovoltaic (PV); wind turbine coupled to permanent synchronous generator (WT-PMSG); battery energy storage (BESS); maximum power point tracking (MPPT); DC/DC converters

Online: 11 August 2021 (15:10:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0202.v1

Implants versus Lipograft – Analysis of Long-Term Results after Congenital Breast Asymmetry Procedure

Vanessa Brebant, Maximilian Weiherer, Vivien Noisser, Stephan Seitz, Lukas Prantl, Andreas Eigenberger

Subject: Medicine And Pharmacology, Surgery Keywords: congenital breast asymmetry; PROM, autologous fat injections, fat grafting, lipograft, implant augmentation, breast augmentation, 3D volumetry, three-dimensional imaging, Breast-QTM; human adipose stem cells

Online: 9 August 2021 (15:06:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0161.v1

Understanding the Nature of the Long–Range Memory Phenomenon in Socio–Economic Systems

Rytis Kazakevičius, Aleksejus Kononovicius, Bronislovas Kaulakys, Vygintas Gontis

Subject: Physical Sciences, Condensed Matter Physics Keywords: long–range memory; 1/f noise; absolute value estimator; anomalous diffusion; ARFIMA; first–passage times; fractional Lèvy stable motion; Higuchi’s method; Mean squared displacement; multiplicative point process

Online: 6 August 2021 (11:22:25 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202108.0118.v1

The Amoebic Self Scale and GPA are related to the academic procrastination sensu lato

Ernest Bielinis, Lidia Bielinis

Subject: Social Sciences, Education Keywords: active procrastination; amoebic self-theory; correlation; grade point average; procrastination; procrastination sensu lato

Online: 4 August 2021 (14:56:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0078.v1

Modeling Insolation, Multi-spectral Imagery and LiDAR Point-cloud Metrics to Predict Plant Diversity in a Temperate Montane Forest

Paul Christian Dunn, Leonhard Blesius

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: biodiversity; insolation, biogeography; lidar; point-cloud; multi-spectral imagery; spatial prediction model; forest canopy

Online: 3 August 2021 (13:05:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0646.v2

Constraints on General Relativity Geodesics by a Covariant Geometric Uncertainty Principle

David Escors, Grazyna Kochan

Subject: Physical Sciences, Quantum Science And Technology Keywords: General relativity; Uncertainty principle; Geodesics; Black hole singularity; zero-point energy

Online: 2 August 2021 (13:38:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0029.v1

θ∗-Weak Contractions and Discontinuity at the Fixed Point With Applications to Matrix and Integral Equations

Atiya Perveen, Waleed Alfaqih, Salvatore Sessa, Mohammad Imdad

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: θ∗-weak contraction; fixed point; discontinuity at the fixed point; property P; matrix equation; integral equations

Online: 2 August 2021 (12:21:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0431.v1

Natural-Fibrous Lime-Based Mortar for the Rapid Retrofitting of Masonry Heritage

Marco Vailati, Micaela Mercuri, Michele Angiolilli, Amedeo Gregori

Subject: Engineering, Automotive Engineering Keywords: masonry; composite; short fibers; natural hydraulic lime; sisal; three-point bending test; fracture energy; strengthening; preservation; sustainability; carbon foot print

Online: 20 July 2021 (09:31:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0110.v1

A Multi-Criteria Assessment Strategy for 3d Printed Porous Polyetheretherketone (Peek) Patient-Specific Implants for Orbital Wall Reconstruction

Neha Sharma, Dennis Welker, Soheila Aghlmandi, Michaela Maintz, Hans-Florian Zeilhofer, Philipp Honigmann, Thomas Seifert, Florian M. Thieringer

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: blow-out; biocompatible materials; computer-aided design; finite element analysis; orbit; implant; orbital fracture; patient-specific modeling; printing; three-dimensional.

Online: 5 July 2021 (15:37:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0002.v1

Hospitalist Perceptions of Barriers to Lung Ultrasound Adoption in Diverse Hospital Environments

Anna M. Maw, P. Michael Ho, Megan A. Morris, Russell E. Glasgow, Amy G. Huebschmann, Juliana G. Barnard, Robert Metter, David M. Tierney, Benji K. Mathews, Edward P. Havranek, Mark Kissler, Michelle Fleshner, Barbra K. Burian, Elke Platz, Nilam J. Soni

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: lung ultrasound; implementation science; point of care ultrasound

Online: 1 July 2021 (07:43:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202009.0532.v2

First Immunohistochemical Evidence of Human Tendon Repair Following Stem Cell Injection: A Case Report and Review of Literature

Eckhard Alt, Ralf Rothoerl, Matthias Hoppert, Hans-Georg Frank, Tobias Wuerfel, Christopher Alt, Christoph Schmitz

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: adipose derived regenerative cells; ADRCs; efficacy; point of care treatment; stem cells; stromal vascular fraction; tendon healing without scar formation; tendon regeneration

Online: 28 June 2021 (15:47:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0665.v1

Coupled Delft3D-Object Model to Predict Mobility and Burial of Munition on Sandy Floor

Peter C. Chu, Vinicius S. Pessanha, Chenwu Fan

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Delft3D; Object Mobility Model; Munitions Mobility and Burial; Object Shields Parameter; Sediment Shields Parameter; Equilibrium Burial Percentage; Sediment Supporting Point

Online: 28 June 2021 (14:24:25 CEST)

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Working Paper ARTICLE

DoA Estimation for FMCW Radar by 3D-CNN

Tzu-Hsien Sang, Feng-Tsun Chien, Chia-Chih Chang, Kuan-Yu Tseng, Bo-Sheng Wang, Jiun-In Guo

Subject: Engineering, Electrical And Electronic Engineering Keywords: FMCW Radar; Deep Learning; Three-Dimension Convolution Network; Direction-of-Arrival Estimation

Online: 14 June 2021 (16:54:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0644.v1

Novel Method to Analytically Obtain the Asymptotic Stable Equilibria States of Extended SIR-type Epidemiological Models

Teddy Lazebnik, Svetlana Bunimovich-Mendrazitsky, Leonid Shaikhet

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: Markov chain; random variable transformation technique; asymptotic stable equilibria state; three age group SIIRD model

Online: 26 May 2021 (14:29:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0564.v1

Heritage-BIM Workflow for Stone Pavements Digital Reproduction

Mattia Intignano, Salvatore Antonio Biancardo, Cristina Oreto, Nunzio Viscione, Rosa Veropalumbo, Francesca Russo, Gianluca Dell’Acqua

Subject: Engineering, Automotive Engineering Keywords: Heritage-BIM; Stone paved road; Procedural Modeling; VPL scripting; CAD; Point Cloud.

Online: 24 May 2021 (11:04:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0504.v1

Research on the Decision-Making Mechanism of Live Commerce Supply Chain Based on Three-Party Evolutionary Game

Jixiao Wu, Yinghui Wang

Subject: Business, Economics And Management, Accounting And Taxation Keywords: livestreaming e-commerce; evolutionary game; multi-party behavior; replicator dynamics equation; three-party game theory

Online: 21 May 2021 (08:32:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0468.v1

3D Reconstruction Method of Rapeseed Plants in the Whole Growth Period Using RGB-D Camera

Xiaowen Teng, Guangsheng Zhou, Yuxuan Wu, Chenglong Huang, Wanjing Dong, Shengyong Xu

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: 3D reconstruction; ICP; Azure Kinect; RGB-D image processing; point cloud filtering; rapeseed

Online: 20 May 2021 (09:52:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0421.v1

Unveiling the Different Reactivity of Bent and Linear Three-Atom-Components Participating in [3+2] Cycloaddition Reactions

Mar Ríos-Gutiérrez, Luis R. Domingo, Fatemeh Ghodsi

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: [3+2] cycloaddition reactions; bent and linear three-atom-components; reactivity; regioselectivity; molecular electron density theory

Online: 18 May 2021 (11:19:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0203.v1

Interaction of Gravitational Field and Orbit in Sun-planet-moon system

Yin Zhu

Subject: Physical Sciences, Acoustics Keywords: Interaction of gravitational field; Three-body problem; Orbital perturbation theory; Repulsive gravity; Neutralization of gravity

Online: 10 May 2021 (14:49:57 CEST)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202104.0641.v1

Three-Dimensional Laser Scanning-Based Method for Identifying Rock Discontinuities

Shengming Hu, Gao Jianglin, liang Hu, Zhiguang Dai, Fang Chen

Subject: Engineering, Automotive Engineering Keywords: three-dimensional laser scanning; rock discontinuity; rock fracture; rock joint; discontinuity orientation.

Online: 23 April 2021 (13:15:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0597.v1

Existence and Uniquenes Solution of Integral Equations via Common Fixed Point Theorems

Gunaseelan Mani, Arul Joseph Gnanaprakasam, Yongjin Li, Zhaohui Gu

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: integral equations; complex partial metric space; common fixed point.

Online: 22 April 2021 (09:19:54 CEST)

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Working Paper ARTICLE

MPPT Circuit Using Time Exponential Rate Perturbation and Observation for Enhanced Tracking Efficiency for a Wide Resistance Range of Thermoelectric Generator

Jie Miao, Houpeng Chen, Yu Lei, Yi Lv, Weili Liu, Zhitang Song

Subject: Engineering, Automotive Engineering Keywords: maximum power point tracking (MPPT); thermoelectric generator (TEG); time exponential rate perturbation and observation (P&O); power modulator

Online: 19 April 2021 (13:26:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0406.v1

Stabilization methodology in foundation soils by ERT-3D. Application in Estepona, South Spain.

Alfonso Gutiérrez-Martín, José I. Yenes, Marta Fernández-Hernández, Ricardo Castedo

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: Electric tomography; three-dimensional; electrodes; seat control; foundations; stabilization methodology.

Online: 15 April 2021 (10:50:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0400.v1

Inhomogeneous Poisson Point Process for Species Distribution Models: Relative Performance of Methods Accounting for Sampling Bias and Imperfect Detection

Yannick MUGUMAARHAHAMA, Adandé Belarmain FANDOHAN, Arsene Ciza MUSHAGALUSA, Idelphonse Akoeugnigan SODE, Romain GLELE KAKAÏ

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Integrated Species distribution models; Maximum likelihood; Point-counts; Presence-only data; Site-Occupancy; species abundance

Online: 15 April 2021 (08:09:25 CEST)

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Working Paper ARTICLE

Large Deviations and Information theory for Sub-Critical SINR Randon Network Models

Enoch Sakyi-Yeboah, Pepertual Saah Andam, Louis Asiedu, Kwabena Doku-Amponsah

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Large deviation principle; Sub-critical SINR random network model; Poisson point process; Empirical power measure; Empirical connectivity measure; Relative entropy; Kullback action

Online: 13 April 2021 (09:17:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0320.v1

"Green into Gold": The Sustainable Development of Commercial Banks from the Perspective of the Equator Principles

duan keyi keyi

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Carbon neutral; Equator Principle; Industrial Bank; "Three Principles"; Factor Analysis; Carbon neutral

Online: 12 April 2021 (14:32:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0086.v1

Rapid and Sensitive Point of Care Detection of MRSA gDNA by Nanoelectrokinetic Sensors

Rania Oueslati, Yu Jiang, Jiangang Chen, Jie Jayne Wu

Subject: Engineering, Electrical And Electronic Engineering Keywords: DNA sensor; point of care diagnostics; methicillin-resistant Staphylococcus aureus; label free biosensor; AC electrokicetics

Online: 5 April 2021 (10:11:51 CEST)

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Preprint REVIEW | doi:10.20944/preprints202004.0201.v2

Detecting the Coronavirus (COVID-19)

Pravin Pokhrel, Changpeng Hu, Hanbin Mao

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: SARS-CoV-2 Detection, SARS-CoV-2 Antibody Test, SARS-CoV-2 Antigen Test, False Negative, False Positive, Sensitivity, Specificity, Point-of-care testing (POCT), SARS-CoV-2 Mutants

Online: 25 March 2021 (15:33:14 CET)

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The COVID-19 pandemic has created huge damage to society and brought panics around the world. Such panics can be ascribed to the seemingly deceptive features of the COVID-19: compared to other deadly viral outspreads, it has medium transmission and mortality rates. As a result, the severity of the causative coronavirus, SARS-CoV-2, was deeply underestimated by the society at the beginning of the COVID-19 outbreak. Based on this, in this review, we define the viruses with features similar to those of SARS-CoV-2 as the Panic Zone viruses. To contain those viruses, accurate and fast diagnosis followed by effective isolation and treatment of patients are pivotal at the early stage of virus breakouts. This is especially true when there is no cure or vaccine available for a transmissible disease, which is the case for current COVID-19 pandemic. As of January 2021, more than two hundred kits for the COVID-19 diagnosis on the market are surveyed in this review, while emerging sensing techniques for SARS-CoV-2 are also discussed. It is of critical importance to rationally use these kits for the efficient management and control of the Panic Zone viruses. Therefore, we discuss guidelines to select diagnostic kits at different outbreak stages of the Panic Zone viruses, SARS-CoV-2 in particular. While it is of utmost importance to use nucleic acid-based detection kits with low false negativity (high sensitivity) at the early stage of an outbreak, the low false positivity (high specificity) gains its importance at later stages of the outbreak. When a society is set to reopen from the lock-down stage of the COVID-19 pandemic, it becomes critical to have antibody based immunoassay kits with high specificity to identify people who can safely return to the society after their recovery of SARS-CoV-2 infections. Given that the emergence of mutant viruses at the beginning of 2021 has complicated current battle against the COVID-19, we also discussed approaches and guidelines to detect viral mutants in the middle of the second wave of the pandemic that started at the end of 2020. Finally, since a massive attack from a viral pandemic requires a massive defense from the whole society, we urge both government and private sectors to research and develop more affordable and reliable point-of-care testing (POCT) kits, which can be used massively by the general public (and therefore called as massive POCT) to contain Panic Zone viruses in future.

Preprint ARTICLE | doi:10.20944/preprints202103.0625.v1

CARTmath - A Mathematical Model of CAR-T Immunotherapy in Preclinical Models

Luciana Rodrigues Carvalho Barros, Emanuelle Arantes Paixão, Andrea Maria Pedrosa Valli, Gustavo Taiji Naozuka, Arthur César Fassoni, Regina Célia Cerqueira Almeida

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: three population mathematical model; CAR-T lymphocytes; memory CAR-T cells; long-term immunity; tumor-induced immunosupression

Online: 25 March 2021 (14:39:02 CET)

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Immunotherapy has gained great momentum with chimeric antigen receptor T cell (CAR-T) therapy, in which patient’s T lymphocytes are genetically manipulated to recognize tumor-specific antigens increasing tumor elimination efficiency. In the last years, CAR-T cell immunotherapy for hematological malignancies achieved a great response rate on patients and is a very promising therapy for several other malignancies. Each new CAR design requires a preclinical proof-of-concept experiment using immunodeficient mouse models. The absence of a functional immune system in these mice makes them simple and suitable to be mathematically modeled. In this work, we developed a three population mathematical model to describe tumor response to CAR-T cell immunotherapy in immunodeficient mouse models, encompassing interactions between a non-solid tumor and CAR-T cells (effector and long-term memory). We account for several phenomena, such as tumor-induced immunosuppression, memory pool formation, and conversion of memory into effector CAR-T cells in the presence of new tumor cells. Individual donor and tumor specificities were considered as uncertainties in the model parameters. Our model is able to reproduce several CAR-T cell immunotherapy scenarios, with different CAR receptors and tumor targets reported in the literature. We found that therapy effectiveness mostly depends on some specific parameters such as the differentiation of effector to memory CAR-T cells, CAR-T cytotoxic capacity, tumor growth rate, and tumor-induced immunosuppression. In summary, our model can contribute to reduce and optimize the number of in vivo experiments with in silico tests to select specific scenarios that could be tested in experimental research. Such in silico laboratory was made available in a Shiny R-based platform called CARTmath. It is an open-source, easy to run simulator, available at github.com/tmglncc/CARTmath or directly on the webpage cartmath.lncc.br, containing this manuscript results as examples and documentation. The developed model, together with the CARTmath platform, provides potential use for assessing different CAR-T cell immunotherapy protocols and associated efficacy, becoming an accessory towards in silico trials.

Preprint SHORT NOTE | doi:10.20944/preprints202103.0604.v1

N,N-bis(2-quinolinylmethyl)benzylamine

Leigh Andre Hunter, Shivani Naidoo, Allen Mambanda

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: H-bonds (-bonding): hydrogen bonds (-bonding); q: quinoline; 3-/2D: three-/two dimensional & VdW: Van der Waal & bqma: bis(2-quinolinylmethyl)amine

Online: 24 March 2021 (16:40:02 CET)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202102.0618.v1

The Concept of Training Image-Based Geostatistics for Spatial Distribution of Hydraulic Conductivity

Fiaz Hussain, Ray-Shyan Wu

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Interpolation; Hydraulic Conductivity; Multi-Point Geostatistics; Training Image

Online: 26 February 2021 (12:47:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202102.0517.v1

New Study of Existence and Dimension of the Set of Solutions for Nonlocal Impulsive Differential Inclusions With Sectorial Operator

Salvatore Sessa, Nawal Alsarori, Kirtiwant Ghadle, Hayel Saleh

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Impulsive fractional differential inclusions; Nonlocal conditions; Fixed point theorems; 10 Mild solutions

Online: 23 February 2021 (14:16:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202102.0453.v1

The Systemic Immune Response in COVID-19 is Associated with a Shift to Formyl-Peptide Unresponsive Eosinophils

Leo Koenderman, Maarten J. Siemers, Corneli Aalst, Suzanne Bongers, Bas Bindels, Giulio Giustarini, Harriët van Goor, Karin Kaasjager, Nienke Vrisekoop

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: SARS-CoV-2; COVID-19; point-of-care flow cytometry; eosinophil; formyl peptide; responsiveness; blood; CD11b; CD62L

Online: 22 February 2021 (10:33:05 CET)

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Working Paper ARTICLE

Diagnostic Accuracy of Point of Care Tests Measuring Glycosylated Haemoglobin (HbA1c) for Glycemic Control: A Field Study in India

Sagar Khadanga, Abhijit Pakhare, Rajnish Joshi

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: HbA1c; point-of-care; diabetes; glycosylated haemoglobin

Online: 18 February 2021 (10:01:13 CET)

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Objectives: This study was performed to estimate diagnostic accuracy of the two commercially available point-of-care tests to identify poor glycemic control defined by HbA1c levels, with HPLC as a reference. Settings: The study was carried at two locations, general medical out-patient department of a teaching medical college in Bhopal (urban), and a primary health care centre in rural area in the state of Madhya Pradesh, India.Participants: All individuals with diabetes mellitus who presented to the health care facility for assessment of glycemic control. We excluded participants who denied a written informed consent. No other exclusions were used. We compared HbA1c estimated from two index tests (Hemocue Hb501, Sweden; SD Biosensor, South Korea) from capillary blood samples with HPLC performed from venous blood, as a reference standard. Primary and secondary outcome measures: Diagnostic properties of index tests such as sensitivity, specificity, positive and negative predictive value and diagnostic accuracy for identifying poor glycemic control were primary outcome measures. Lin’s concordance correlation coefficient (CCC) was secondary outcome measure.Results: Out of 114 patients, all received reference standard, 103-Hemocue A1C test, and 110- SD Biosensor test. Overall both the index-tests had similar diagnostic accuracy estimates. The area under the Receiver Operating Curve for SDA1c device was 0.935 (95%CI 0.886-0.983), and for Hemocue device was 0.938 (95%CI 0.893-0.984). The Hemocue device HbA1c value of above 7.0 (positive) correctly predicted poor glycemic control 92% times (81.58% for SD device). There were 4 vs. 11 device failures and 14 vs. 12 failures with SD and Hemocue respectively. Ambient air temperatures were no different for the device test failures.Conclusions: Commercially available point-of-care tests evaluated in this study are comparable and an acceptable alternative to HPLC based measurements for assessment of glycemic control. Tests and device failure rates of both the index tests are similar.

Preprint ARTICLE | doi:10.20944/preprints202102.0323.v1

Free and Open-Source Software for Geographic Information System on Coastal Management: A Study Case of Sea-Level Rise in Southern Brazil

Lucas Terres de Lima, Sandra Fernández-Fernández, Carlos V. C. Weiss, Volney Bitencourt, Cristina Bernardes

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Climate Change; Modeling; Coastal Hazards; End Point Rate; Uncertainty Bathtub; Bruun Rule

Online: 16 February 2021 (13:30:10 CET)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202102.0304.v1

Field Information Modeling (FIM)™: Best Practices using Point Clouds

Reza Maalek

Subject: Engineering, Automotive Engineering Keywords: Field Information Modeling (FIM)™; point cloud to BIM; point cloud vs. BIM; n-D information modeling; digital engineering and construction

Online: 12 February 2021 (13:19:06 CET)

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