REVIEW
|
doi:10.20944/preprints202301.0034.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
migraine; neuropathic pain; calcitonin gene-related peptide (CGRP); kynurenine; glia; cytokines; neuroinflammation; transient receptor potential (TRP) ion channels; endocannabinoids
Online: 4 January 2023 (01:53:45 CET)
ARTICLE
|
doi:10.20944/preprints202212.0523.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Roux-en-Y gastric bypass bariatric surgery; vitamin D; Vitamin D Receptor; FokI (rs2228570); TaqI (rs731236)
Online: 28 December 2022 (01:44:32 CET)
REVIEW
|
doi:10.20944/preprints202212.0298.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Endocytosis; Phagocytosis; Pinocytosis; Receptor endocytosis signaling; Chronic diseases
Online: 16 December 2022 (08:07:01 CET)
ARTICLE
|
doi:10.20944/preprints202212.0254.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
plasma membranes; secretion; ACBD3; KDEL receptor; Rab4; Rab11
Online: 14 December 2022 (09:12:18 CET)
ARTICLE
|
doi:10.20944/preprints202212.0063.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Herpes simplex virus type 1 (HSV-1); antigen-receptor binding; equilibrium constant; Gibbs energy of binding; biothermodynamics
Online: 5 December 2022 (07:07:46 CET)
ARTICLE
|
doi:10.20944/preprints202211.0482.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Biothermodynamics of viruses; HIV-1; Binding constant; Gibbs energy of binding; Antigen-receptor binding
Online: 25 November 2022 (12:44:38 CET)
REVIEW
|
doi:10.20944/preprints202211.0122.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Endocannabinoid system; receptor cannabinoid; endocannabinoids ligands; phytocannabinoids; Integrative and Complementary Health Practices
Online: 7 November 2022 (11:36:46 CET)
ARTICLE
|
doi:10.20944/preprints202211.0031.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
GPCRs; Kappa opioid receptor; Salvinorin A; Natural products; docking; molecular dynamics simulations; dynophores
Online: 1 November 2022 (14:20:16 CET)
REVIEW
|
doi:10.20944/preprints202209.0339.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
cis-prenyltransferase; DHDDS; dolichol; Nogo-B receptor; retinal degeneration; RP59
Online: 22 September 2022 (10:18:11 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0253.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Abdominal aortic aneurysm; Type I interferon receptor, Leukocytes; Angiogenesis
Online: 19 September 2022 (02:08:07 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0198.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Cholecystokinin-2 receptor; minigastrin; peptide receptor radionuclide therapy; lutetium-177, theranostics
Online: 14 September 2022 (08:39:42 CEST)
REVIEW
|
doi:10.20944/preprints202208.0419.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alcohol; Dynorphin; Kappa Opioid Receptor; DYN/KOR; Anxiety; Depression; Negative Affective States; Withdrawal; Microdialysis; Dynorphin-immunoreactivity
Online: 24 August 2022 (10:52:52 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0324.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
T cytotoxic cells; Leukocyte-associated Immunoglobulin-like Receptor-1; LAIR-1; Hepatitis C virus genotype 4; HCV G4; hepatocellular carcinoma; cirrhosis; immune inhibitory checkpoints; inflammation; prognosis; insulin resistance
Online: 17 August 2022 (11:38:10 CEST)
REVIEW
|
doi:10.20944/preprints202208.0082.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
therapy resistance; tumor microenvironment; metabolic reprogramming; purinergic receptor; cancer metabolism; immunometabolism
Online: 3 August 2022 (10:35:30 CEST)
ARTICLE
|
doi:10.20944/preprints202207.0409.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
QNBC (Quadruple negative breast cancer); AR (Androgen receptor); AA (African American); CA (Caucasian); BC (Breast cancer)
Online: 27 July 2022 (04:07:32 CEST)
REVIEW
|
doi:10.20944/preprints202207.0256.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer; immunotherapy; adverse events; immune checkpoints inhibitors; chimeric antigen receptor therapy; bispecific antibodies; toxicity; renal; oncology
Online: 18 July 2022 (09:21:56 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202207.0220.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Hepatitis B virus; HepG2-NTCP cells; Immunofluorescence; Sodium taurocholate cotransporting polypeptide (NTCP) Receptor; Subcloning; Limiting dilution; Myrcludex B
Online: 14 July 2022 (12:06:08 CEST)
REVIEW
|
doi:10.20944/preprints202207.0180.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
plasma membrane; membrane domains; nanodomains; neurotransmitter receptors; cannabinoids; acetylcholine receptor; cannabinoid receptor.
Online: 12 July 2022 (09:17:01 CEST)
ARTICLE
|
doi:10.20944/preprints202207.0058.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
human interferon gamma; human interferon gamma receptor; receptor binding; heparan sulfate; co-receptor; molecular dynamics simulations; sodium chlorate; kynurenine antiproliferative assays; hIFNγ signalling
Online: 5 July 2022 (04:43:05 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0348.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Naltrexone; mu-opioid receptor; MD simulations; MMGBSA; binding free energy
Online: 27 June 2022 (04:09:30 CEST)
REVIEW
|
doi:10.20944/preprints202206.0160.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; HER2-positive; estrogen receptor positive; triple-positive; HER2-targeted therapy; immunotherapy
Online: 10 June 2022 (11:03:05 CEST)
REVIEW
|
doi:10.20944/preprints202205.0290.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Cholesterol; PCSK9 inhibitors; HMG-CoA; LDL receptor; statins
Online: 23 May 2022 (10:01:24 CEST)
REVIEW
|
doi:10.20944/preprints202205.0269.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
inflammation; calcium-sensing receptor; burns; chemokines; NLRP3 inflammasome
Online: 20 May 2022 (04:01:33 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0224.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
age-related macular degeneration; light-induced photoreceptor degeneration; anti-inflammatory drug; toll-like receptor 4
Online: 17 May 2022 (08:03:11 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0165.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
Coronavirus SARS-CoV-2; seroprevalence; antibodies; nucleocapsid antigen; antigen receptor binding domain; seropositivity; St. Petersburg; volunteers; vaccination
Online: 18 April 2022 (10:42:54 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0091.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
SARS-CoV-2; SARS-CoV; RT-PCR; Sanger sequencing; RT-qPCR; receptor-binding domain (RBD); N-terminal domain (NTD); Omicron; multi-allelic SNPs; false-positive
Online: 12 April 2022 (03:57:29 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0082.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
Caco2/HT-29 cells; lipopolysaccharide(LPS); mucins; focal adhesion pathway; ECM receptor in-teraction pathway
Online: 8 April 2022 (14:04:17 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0327.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
tryptophan; kynurenine; kynurenic acid; passive avoidance; cognitive domain; memory; cognitive enhancer; neurotransmission; receptor blockers; translational
Online: 24 March 2022 (08:57:45 CET)
REVIEW
|
doi:10.20944/preprints202203.0059.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
vitamin D; calcifediol; cailcitriol; graft-versus-host disease; vitamin D receptor (VDR)
Online: 3 March 2022 (10:02:45 CET)
ARTICLE
|
doi:10.20944/preprints202202.0090.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Gastroenteropancreatic neuroendocrine neoplasms; patient-derived xenograft; tumor spheroids; somatostatin receptor-2; Near infrared-labelled octreotide analog
Online: 7 February 2022 (13:12:50 CET)
ARTICLE
|
doi:10.20944/preprints202202.0082.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Trace amine-associated receptor 5; antagonist; AtomNet; BRET.
Online: 7 February 2022 (11:57:16 CET)
ARTICLE
|
doi:10.20944/preprints202201.0385.v1
Subject:
Social Sciences,
Behavior Sciences
Keywords:
Trace amine-associated receptor 5; cognition; decision-making; switch task
Online: 25 January 2022 (14:49:51 CET)
REVIEW
|
doi:10.20944/preprints202201.0117.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
G protein-coupled receptor; mouse models; skin cancer; UVR; drug; network
Online: 10 January 2022 (13:41:08 CET)
REVIEW
|
doi:10.20944/preprints202112.0518.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
B-cell non-Hodgkin lymphoma (B-NHL); B-cell receptor (BCR); Bruton’s tyrosine kinase (BTK); spleen tyrosine kinase (SYK); phosphoinositide-3-kinase (PI3K); ibrutinib; acalabrutinib; copanlisib; idelalisib; umbralisib; fostamatinib; combination therapies
Online: 31 December 2021 (12:23:29 CET)
REVIEW
|
doi:10.20944/preprints202112.0469.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
astrocyte; gamma-amino butyric acid (GABA); GABA transporter (GAT); GABAA receptor; glutamic acid decarboxylase (GAD); glycine; glycine receptor; glycine transporter (GlyT); K+-Cl- co-transporter 2 (KCC2); vesicular GABA transporter (VGAT)
Online: 29 December 2021 (14:27:41 CET)
ARTICLE
|
doi:10.20944/preprints202111.0523.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Keratinocytes; epidermis; Pemphigus vulgaris; autoimmune disease; autoantibodies, Fc receptor neonatal; efgartigimod
Online: 29 November 2021 (11:46:04 CET)
ARTICLE
|
doi:10.20944/preprints202111.0396.v1
Subject:
Biology And Life Sciences,
Ecology, Evolution, Behavior And Systematics
Keywords:
Progesterone Receptor; Mineralocorticoid Receptor; Evolution; Zebrafish
Online: 22 November 2021 (13:52:50 CET)
ARTICLE
|
doi:10.20944/preprints202110.0384.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
thiadizines; serotonin transporter (SERT); serotonin-1A receptor; serotonin-3 receptor; docking; docking energy; binding affinity; binding mechanism; c-Fos; immunohistochemistry; electrophysiology
Online: 26 October 2021 (12:32:43 CEST)
ARTICLE
|
doi:10.20944/preprints202110.0304.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
1,25-dihydroxyvitamin D; vitamin D receptor; vitamin D receptor; fibroblast growth factor receptor; signal transduction; differentiation
Online: 21 October 2021 (10:52:39 CEST)
REVIEW
|
doi:10.20944/preprints202110.0016.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
prostate cancer; castrate-resistant growth; metastases; androgen receptor; glucocorticoid receptor; cytokines; transmembrane receptors; cell signaling; pharmacological targeting; neuroendocrine differentiation; lineage plasticity; prostate cancer stem cells
Online: 1 October 2021 (12:19:03 CEST)
REVIEW
|
doi:10.20944/preprints202110.0005.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Brown adipose tissue; beige adipose tissue; obesity; cold exposure; uncoupling protein-1, beta-adrenergic receptor; energy expenditure; adipose browning; micro-RNA
Online: 1 October 2021 (11:30:39 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0316.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
temporal lobe epilepsy; hippocampus; 4-aminopyridine; epilepsy model; long-term potentiation; AMPA receptor.
Online: 17 September 2021 (12:45:31 CEST)
REVIEW
|
doi:10.20944/preprints202109.0123.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Genistein; Estrogen receptor; BRCA-1; Cell cycle; Tumor suppressor gene; Molecular pharmacology; Synergistic activity.
Online: 7 September 2021 (11:59:15 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0007.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
receptor; distribution; BMP; BMPR; center of mass; micropattern
Online: 2 August 2021 (09:29:25 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0665.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
cannabinoid receptor; inflammation; astrocytes; immunohistochemistry
Online: 29 July 2021 (14:11:55 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0611.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
pituitary adenylate cyclase-activating peptide (PACAP); PAC1 receptor; doxycycline; minocycline; positive allosteric modulator; Schwann cells; tissue plasminogen activator (tPA); urokinase plasminogen activator (uPA)
Online: 27 July 2021 (21:51:30 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0585.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Functional receptor; Hepatitis B virus; Polymorphism; Sodium taurocholate co-transporting polypeptide; hepatic fibrosis; Egypt
Online: 26 July 2021 (14:42:42 CEST)
REVIEW
|
doi:10.20944/preprints202107.0551.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
epidermal growth factor receptor; ErbB; biomarker; meningioma; intracranial tumor
Online: 23 July 2021 (22:06:24 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0502.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
mushroom; immune checkpoints; Axl receptor; lung cancer; dendritic cells; immune response.
Online: 21 July 2021 (15:43:11 CEST)
REVIEW
|
doi:10.20944/preprints202107.0353.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Lung cancer; Adjuvant treatment; Non-small-cell lung carcinoma (NSCLC); Epidermal growth factor receptor (EGFR); Tyrosine kinase inhibitor (TKI)
Online: 15 July 2021 (10:16:30 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
histamine; histamine H1 receptor; histamine H4 receptor; itch; TRPV1; TRPA1; dorsal root ganglion neurons (DRG); Ca2+-imaging
Online: 15 July 2021 (10:12:01 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0295.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2 spike protein; ACE2 host receptor; nanobodies; molecular dynamics; mutational sensitivity; binding free energy; allosteric interactions; signal transmission
Online: 13 July 2021 (11:18:02 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
cannabinoid receptor 2; epilepsy; cAMP, M-current; anti-inflammatory
Online: 6 July 2021 (17:09:20 CEST)
REVIEW
|
doi:10.20944/preprints202106.0692.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Ryanodine receptor; skeletal muscle; cardiac muscle; exercise and injury; heart function; diet
Online: 29 June 2021 (08:37:53 CEST)
REVIEW
|
doi:10.20944/preprints202106.0377.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
aa = amino acids; ACE-2 = receptor angiotensin-converting enzyme 2; cDNA = complementary DNA; mRNA = messenger RNA; orf = open reading frame; RBD = receptor binding protein; S-protein = Spike protein; SARS-CoV-2 = severe respiratory syndrome coronavirus 2; Vaccines.
Online: 22 June 2021 (11:53:34 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0531.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Microglia; Extracellular vesicles; migration; P2X4 receptor; MFG-E8; lipid rafts
Online: 22 June 2021 (08:26:41 CEST)
REVIEW
|
doi:10.20944/preprints202106.0176.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
chronic hepatitis B; covalently closed circular DNA; viral integration; transcription factor; nuclear receptor; transcriptional inhibitor; RNA interference
Online: 7 June 2021 (12:43:06 CEST)
COMMUNICATION
|
doi:10.20944/preprints202106.0091.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
COVID-19; SARS-CoV-2 variant; lateral flow immunoassay; spike protein; receptor binding domain (RBD); neutralizing antibody; therapeutic antibody cocktail; epitope binning; rapid neutralization test; ACE2
Online: 2 June 2021 (16:11:29 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0030.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
PGE2; Th1/Th17; EP4 receptor; T cell differentiation
Online: 1 June 2021 (11:59:27 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0694.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Congenital hypothyroidism; FOXE1; Mexican population; multiplex ligation-dependent probe amplification (MLPA); NKX2-1; NKX2-5; PAX8; polyalanine tract; protein modeling; thyroid dysgenesis; TSH receptor
Online: 28 May 2021 (11:15:14 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0634.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
silica; nanoparticles; ATP; purinergic receptor; airway; epithelial cell
Online: 26 May 2021 (11:45:50 CEST)
REVIEW
|
doi:10.20944/preprints202105.0625.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Toll-Like Receptor; Innate Immunity; Inflammation; Anti-inflammation
Online: 26 May 2021 (08:17:01 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0525.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
COVID-19; glycyrrhizin; mineralocorticoid receptor; toll like receptor 4; angiotensin converting enzyme; aldosterone
Online: 21 May 2021 (15:11:30 CEST)
REVIEW
|
doi:10.20944/preprints202105.0414.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
: mineralocorticosteroid receptor antagonist (MRA); angiotensin converting enzyme 2 (ACE2); SARS-CoV-2; transmembrane protease receptor serine 2; furin; plasmin
Online: 18 May 2021 (10:39:03 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0297.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Protein Kinase Receptor (PKR); Mammarenavirus; Interferon; Innate immune response; Mx1; ISG15; CCL5
Online: 13 May 2021 (13:27:07 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0087.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
G-Protein Coupled Receptors; beta-3-adrenergic receptor; receptor desensitization
Online: 6 May 2021 (13:16:27 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0045.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Cramping; electromyography; electrical stimulation; cramp induction; flexor hallucis brevis; pickle juice; oropharyngeal transient receptor
Online: 5 May 2021 (12:23:02 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0732.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Epidermal Growth Factor Receptor (EGFR); mutations, EGFR tyrosine kinase inhibitor; molecular epidemiology; Non-small-cell lung cancer
Online: 28 April 2021 (07:55:22 CEST)
REVIEW
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
amyloid-β; endotoxin; short chain fatty acids; clasmatodendrosis; cytokines; neurovascular unit; vagus nerve; Toll-like Receptor 4
Online: 26 April 2021 (13:22:47 CEST)
REVIEW
|
doi:10.20944/preprints202104.0517.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
CAR T-cells; chimeric antigen receptor T cells; cytokine release syndrome; central nervous system toxicity; neurotoxicity; adverse events; pathophysiology
Online: 19 April 2021 (21:17:34 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0223.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Apoptosis; PARP; Caspase 3; Neurodegeneration; GPR4 receptor; MPTP; Parkinson’s disease
Online: 8 April 2021 (09:12:06 CEST)
REVIEW
|
doi:10.20944/preprints202103.0401.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
insulin; insulin receptor; brain insulin resistance; mitochondria; brain; neuron; H2O2; glutamate excitotoxicity.
Online: 15 March 2021 (17:38:24 CET)
ARTICLE
|
doi:10.20944/preprints202103.0379.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
γδ T cell; T cell receptor; TRA/TRD locus; Variable, Diversity, Joining and Constant genes; complementarity determining region-3; δ chain; somatic hypermutation; Camelidae
Online: 15 March 2021 (12:32:41 CET)
REVIEW
|
doi:10.20944/preprints202103.0372.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
insulin; insulin receptor; brain insulin resistance; mitochondria; brain; neuron; H2O2; glutamate excitotoxicity.
Online: 15 March 2021 (11:46:08 CET)
ARTICLE
|
doi:10.20944/preprints202103.0273.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
testicular germ cell tumors (TGCTs); human seminoma; p75 neurotrophin receptor (p75NTR); p75NTR -signaling.
Online: 9 March 2021 (14:52:34 CET)
REVIEW
|
doi:10.20944/preprints202103.0231.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Tryptophan metabolism; Kynurenine; Indoleamine 2,3-dioxygenase; Aryl hydrocarbon receptor; Microbiome; Indole; Colon cancer.
Online: 8 March 2021 (15:55:29 CET)
ARTICLE
|
doi:10.20944/preprints202102.0318.v3
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Machine Learning; Artificial Intelligence; Androgen Receptor; Random Forest; Deep Neural Network; Convolutional
Online: 24 February 2021 (13:14:01 CET)
ARTICLE
|
doi:10.20944/preprints202102.0397.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
pyrazolopyrimidinone; hydrazide-hydrazone; antitumor lead compound; cytotoxic activity; antiproliferative activity; molecular docking; epidermal growth factor receptor; G-quadruplex DNA; KRAS; circular dichroism
Online: 17 February 2021 (14:05:44 CET)
ARTICLE
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
T cell receptor; dolphin genome; TRB locus; TRBV; TRBJ; TRBD and TRBC genes; TRA and TRB gene expression analysis; multiple sequence alignments (MSA); 3D modelisation; IMGT
Online: 11 February 2021 (13:26:26 CET)
ARTICLE
|
doi:10.20944/preprints202102.0276.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
liver receptor homolog-1; perilipin 5; triglyceride; fasting; lipid droplet
Online: 11 February 2021 (10:36:17 CET)
REVIEW
|
doi:10.20944/preprints202101.0458.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
blood-brain barrier; transient receptor potential cation channels; ischemic stroke; neuroprotection; calcium signaling; cAMP response element-binding protein
Online: 25 January 2021 (09:20:51 CET)
REVIEW
|
doi:10.20944/preprints202101.0393.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Breast cancer; Angiogenesis; Lymphangiogenesis; Cancer Stem cells, microRNA; EP4 receptor; Immune check-point inhibitor
Online: 19 January 2021 (17:40:53 CET)
REVIEW
|
doi:10.20944/preprints202101.0388.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Thymic selection; T-cell development; T-cell receptor (TCR); mathematical modelling; multiscale models; complex systems; ordinary differential equations (ODE); agent-based models.
Online: 19 January 2021 (16:39:50 CET)
ARTICLE
|
doi:10.20944/preprints202101.0319.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
thromboxane A2 and prostaglandin H2 receptor (TPR) antagonist; ONO-8809; renal disorders; salt-overload; stroke-prone spontaneously hypertensive rat (SHRSP); hypertension; oxidative stress
Online: 18 January 2021 (11:32:11 CET)
REVIEW
|
doi:10.20944/preprints202012.0795.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
T cells; chimeric antigen receptor; transgenic T-cell receptor; tumor-infiltrating lymphocytes; exhaustion; terminal differentiation; senescence; apoptosis; adoptive cell transfer; immunotherapy
Online: 31 December 2020 (12:16:55 CET)
REVIEW
|
doi:10.20944/preprints202012.0675.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Breast cancer; Estrogen Receptor; PI3K-AKT-mTOR; anti-estrogen resistance
Online: 28 December 2020 (09:22:17 CET)
ARTICLE
|
doi:10.20944/preprints202012.0670.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
In silico; Estrogen Receptor; Hibiscus sabdariffa L.; Phytochemical; Anthocyanin; SERM
Online: 25 December 2020 (16:03:32 CET)
ARTICLE
|
doi:10.20944/preprints202012.0635.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Free fatty acid receptor 2; microbiota; metabolite; sensor; G-coupled protein receptor; signaling; Alzheimer’s disease; senescence; C. elegans
Online: 24 December 2020 (14:56:00 CET)
REVIEW
|
doi:10.20944/preprints202011.0276.v2
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Vitamin D; VDR; inflammation; microbiome; metabolites; nuclear receptor; probiotics; tight junctions
Online: 24 December 2020 (09:55:13 CET)
ARTICLE
|
doi:10.20944/preprints202012.0513.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
apoferritin nanocarriers; controlled drug delivery; idarubicin; ferritin receptor targeting; folate receptor targeting
Online: 21 December 2020 (11:28:08 CET)
REVIEW
|
doi:10.20944/preprints202012.0441.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
dystrohinopathy; Duchenne muscular disease; Becker muscular disease; dystrophic deficient cardiomyopathy; cardiac fibrosis; renin angiotensin system; angiotensin 2; angiotensin converter enzyme inhibitors; angiotensin receptor blockers; heart failure
Online: 18 December 2020 (07:18:16 CET)
ARTICLE
|
doi:10.20944/preprints202012.0376.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Desipramine; Autophagy; Apoptosis; Death receptor-5; TRAIL
Online: 15 December 2020 (12:09:09 CET)
REVIEW
|
doi:10.20944/preprints202012.0288.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
desmoplastic small round cell tumor; treatment; prognosis; surgery; radiotherapy; chemotherapy; tyrosine kinase receptor; target therapy; rare disease
Online: 11 December 2020 (15:53:20 CET)
REVIEW
|
doi:10.20944/preprints202012.0176.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Vitamin D; COVID-19; SARS-CoV-2; endothelialithis; CYP27B1; vitamin D receptor; CYP24A1
Online: 7 December 2020 (19:43:48 CET)
ARTICLE
|
doi:10.20944/preprints202011.0709.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Sphingosine-1-phosphate receptor analogue; fingolimod phosphate; neuroprotection; mitochondrial damage; glycolytic pathway; pentose phosphate pathway; REDOX homeostasis.
Online: 30 November 2020 (08:31:50 CET)
REVIEW
|
doi:10.20944/preprints202011.0445.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Peptide Receptor Radionuclide Therapy; PRRT; 68Ga-labeled somatostatin analogue; 18F-FDG; response assessment; RECIST; SWOG; WHO; neuroendocrine tumors; NET
Online: 17 November 2020 (10:35:21 CET)
ARTICLE
|
doi:10.20944/preprints202011.0363.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
cannabinoid receptor 1; synthetic cannabinoids; quantitative structure-activity relationship; multiple linear regression; partial least squares regression; dependence and abuse potential
Online: 13 November 2020 (07:19:36 CET)
ARTICLE
|
doi:10.20944/preprints202011.0333.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
peroxiporins; oxidative stress; hydrogen peroxide; water channels; Sigma1 receptors; Sigma1 receptor modulators; neurodegenerative diseases
Online: 12 November 2020 (09:33:34 CET)
ARTICLE
|
doi:10.20944/preprints202010.0504.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
glycine transporter; glycine receptor; analgesics; lipids
Online: 26 October 2020 (08:46:31 CET)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
glucocorticoid receptor; allosteric; elephant shark; nuclear receptors; evolution
Online: 19 October 2020 (10:03:00 CEST)