REVIEW
|
doi:10.20944/preprints202401.1321.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Chagas disease; Trypanosoma cruzi; Natural products; Therapeutic approaches; Anti-parasitic compounds; Plant-derived compounds
Online: 17 January 2024 (12:04:26 CET)
ARTICLE
|
doi:10.20944/preprints202311.1972.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
patient-derived HCC cell lines; in-vitro investigating; therapeutic testing; orthotopic transplantation
Online: 30 November 2023 (10:52:44 CET)
ARTICLE
|
doi:10.20944/preprints202308.0052.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
COVID-19; therapeutic antibody; SARS-CoV-2 Delta; SARS-CoV-2 Omicron; toxicology
Online: 1 August 2023 (11:27:40 CEST)
REVIEW
|
doi:10.20944/preprints202308.1134.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
NAFLD; NASH; pathogenesis; genetic factors; dietary factors; environmental factors; therapeutic strategies
Online: 15 August 2023 (12:51:25 CEST)
ARTICLE
|
doi:10.20944/preprints202311.1214.v1
Subject:
Public Health And Healthcare,
Physical Therapy, Sports Therapy And Rehabilitation
Keywords:
multiple sclerosis; therapeutic climbing; motivation; training conditions; neurorehabilitation; qualitative research
Online: 20 November 2023 (05:01:25 CET)
REVIEW
|
doi:10.20944/preprints202308.0520.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
SARS-CoV-2; spike protein; mutations; viral infectivity; pathogenesis; vaccine efficacy; immune evasion; antibody neutralization; T-cell response; therapeutic targeting
Online: 7 August 2023 (10:12:28 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0533.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
therapeutic drug monitoring (TDM); extracorporeal therapies; CKRT; hemoadsorption; cytosorb; antimicrobials; clearance; mass removal
Online: 7 August 2023 (10:46:18 CEST)
REVIEW
|
doi:10.20944/preprints202401.0524.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
transdermal drug delivery system; skin permeation; permeation enhancers; quality by design ap-proach; therapeutic applications
Online: 8 January 2024 (06:41:04 CET)
ARTICLE
|
doi:10.20944/preprints202308.0037.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
NONMEM; covariate analysis; PopPK; therapeutic drug monitoring; children.
Online: 1 August 2023 (10:00:25 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1448.v2
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Chronic wounds; Dermal samples; Fibroblast cells; Low-Level Laser Therapy (LLLT); Migration; Proliferation; Therapeutic intervention; Wound healing; Wound margins; Wound tissue
Online: 30 August 2023 (02:33:14 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0900.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Corneal blindness; microbial keratitis; Pythium insidiosum; therapeutic penetrating keratoplasty
Online: 13 June 2023 (08:51:35 CEST)
REVIEW
|
doi:10.20944/preprints202307.2136.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Epilepsy; Pediatric Drug Development (PDD); Therapeutic Orphans; Extrapolation of efficacy from adults to children; Antiseizure Medications (ASMs); Pediatric Investigation Plan (PIP)
Online: 1 August 2023 (02:49:45 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0259.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
Asphyxia; therapeutic hypothermia; newborns; glial fibrillary acidic protein (GFAP); cytokines; chemokines; neuroinflammation
Online: 14 March 2023 (13:22:48 CET)
REVIEW
|
doi:10.20944/preprints202307.0397.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
Rosacea; inflammation; inflammatory skin disease; pathogenesis; therapeutic strategies; treatment options
Online: 6 July 2023 (09:02:30 CEST)
REVIEW
|
doi:10.20944/preprints202309.0749.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
brain tumor; glioma; neuronal system tumor; deubiquitinase (DUB); Endoplasmic Reticulum Associated Degradation (ERAD); immune response; therapeutic target; DNA repair
Online: 12 September 2023 (11:04:42 CEST)
REVIEW
|
doi:10.20944/preprints202212.0348.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
antibiotic; biofilm; infections; Staphylococcus aureus; therapeutic antibiofilm
Online: 20 December 2022 (03:24:37 CET)
ARTICLE
|
doi:10.20944/preprints202402.0309.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
Severe Acute Malnutrition, child development, fatty acids, ready-to-use therapeutic foods, psychosocial stimulation
Online: 6 February 2024 (10:38:22 CET)
ARTICLE
|
doi:10.20944/preprints202402.1186.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Staphylococcus aureus infection; methicillin-resistant bacteria; clinical isolates; planktonic bacteria; biofilm; rifabutin; liposomes; therapeutic strategy
Online: 21 February 2024 (04:36:14 CET)
REVIEW
|
doi:10.20944/preprints202309.0186.v1
Subject:
Public Health And Healthcare,
Primary Health Care
Keywords:
Inherited Retinal Dystrophies; Retinitis Pigmentosa; therapeutic strategies; cell therapies
Online: 4 September 2023 (11:29:44 CEST)
REVIEW
|
doi:10.20944/preprints202306.0770.v1
Subject:
Medicine And Pharmacology,
Veterinary Medicine
Keywords:
Clostridium botulinum; botulism; neurotoxin; BoNT; therapeutic; antibodies; horse; dog; cat; farm animals
Online: 12 June 2023 (05:23:03 CEST)
REVIEW
|
doi:10.20944/preprints202308.2204.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
COVID-19; Social isolation stress; Neuropsychiatric disorders; Biopsychosocial vulnerability; Therapeutic strategies
Online: 1 September 2023 (07:30:29 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1190.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
Birth asphyxia; nSOFA; outcome prediction; neonate; Hypoxic-ischemic encephalopathy (HIE); therapeutic hypothermia; resuscitation; organ dysfunction; biomarker; mortality
Online: 29 April 2023 (02:52:55 CEST)
REVIEW
|
doi:10.20944/preprints202311.1323.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Massive trauma; Neuropsychology; Neuroplasticity; Clinical Intervention; Cognitive Rehabilitation; therapeutic interventions
Online: 22 November 2023 (07:17:40 CET)
ARTICLE
|
doi:10.20944/preprints202303.0085.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Chronic hepatitis B infection; Therapeutic vaccines; Regulatory T cells; Functional cure; GMI-HBVac; Mafosfamide
Online: 6 March 2023 (03:37:38 CET)
ARTICLE
|
doi:10.20944/preprints202403.0153.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
Recombinant FVIIa; Postpartum Hemorrhage; Pregnancy Complications, Hematologic; Coagulants, therapeutic use; Thromboembolic events; Delivery, Obstetric; Maternal mortality
Online: 4 March 2024 (11:23:01 CET)
REVIEW
|
doi:10.20944/preprints202312.0434.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Antimicrobial peptides; Classification; Disease conditions; Therapeutic action and Clinical advancements
Online: 7 December 2023 (07:25:37 CET)
REVIEW
|
doi:10.20944/preprints202309.0857.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Hepatocellular Carcinoma; Gut Microbiome, Biomarkers; Therapeutic Target; Immunotherapy
Online: 14 September 2023 (02:27:34 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0468.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
dasatinib; imatinib; nilotibin; ponatinib; children; therapeutic drug monitoring; sex and gender pharmacology; personalized medicine.
Online: 7 August 2023 (11:53:12 CEST)
REVIEW
|
doi:10.20944/preprints202402.0911.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
indole alkaloids; marine resources; biological activity; therapeutic application; synthetic strategies
Online: 16 February 2024 (14:17:18 CET)
REVIEW
|
doi:10.20944/preprints202306.1955.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; CDK4/6 inhibitors; estrogen receptor; therapeutic resistance
Online: 28 June 2023 (07:39:44 CEST)
ARTICLE
|
doi:10.20944/preprints202305.2102.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
18F-DCFPyL; 18F-Fluorocholine; miTNM; PSA level; PSA kinetics; therapeutic impact
Online: 30 May 2023 (09:55:10 CEST)
REVIEW
|
doi:10.20944/preprints202307.0542.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
eye health; visual impairment; age-related macular degeneration; glaucoma; retinitis pigmentosa; diabetic retinopathy; therapeutic strategies
Online: 10 July 2023 (08:29:38 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1509.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
HCV; cascade of care; therapeutic community; intravenous drug use
Online: 19 January 2024 (14:43:54 CET)
REVIEW
|
doi:10.20944/preprints202309.0044.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
MET alterations; cancer progression; invasive growth; therapeutic targeting.
Online: 1 September 2023 (10:03:30 CEST)
REVIEW
|
doi:10.20944/preprints202401.1751.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
lung cancer; conventional treatment; innovative therapeutic modalities; combination therapy
Online: 24 January 2024 (13:41:06 CET)
REVIEW
|
doi:10.20944/preprints202310.2086.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Bacteriophage-derived proteins; therapeutic potential
Online: 1 November 2023 (03:43:47 CET)
REVIEW
|
doi:10.20944/preprints202310.2022.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
SREBPs; NAFLD; NASH; fibrosis; hepatocellular carcinoma (HCC); lipogenesis, endoplasmic reticulum (ER) stress; therapeutic target
Online: 31 October 2023 (09:02:44 CET)
REVIEW
|
doi:10.20944/preprints202311.0434.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
natural polysaccharide; composite hydrogel; wound healing; therapeutic agent
Online: 7 November 2023 (11:14:38 CET)
REVIEW
|
doi:10.20944/preprints202311.0406.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
ALS; C. elegans model; cellular mechanism; therapeutic application
Online: 7 November 2023 (06:44:34 CET)
REVIEW
|
doi:10.20944/preprints202305.1151.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
fusion proteins; inhibitor; therapeutic; cancer
Online: 16 May 2023 (10:32:09 CEST)
ARTICLE
|
doi:10.20944/preprints202311.0232.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
human papillomavirus; adenoviral vectors; adenovirus-vector-based vaccines; therapeutic vaccines; E1 HPV16; T cell expansion
Online: 3 November 2023 (10:08:20 CET)
REVIEW
|
doi:10.20944/preprints202305.0014.v1
Subject:
Public Health And Healthcare,
Physical Therapy, Sports Therapy And Rehabilitation
Keywords:
HBV/HDV coinfection; Evolving antiviral drugs; innovative immune therapeutic agents; combination of antiviral and immune therapy
Online: 1 May 2023 (04:18:06 CEST)
REVIEW
|
doi:10.20944/preprints202402.0510.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
clusterin; human cancer; targeted treatment; resistance; therapeutic potential.
Online: 8 February 2024 (10:23:57 CET)
ARTICLE
|
doi:10.20944/preprints202309.1490.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
glioblastoma; astrocytoma; lipid accumulation; mitochondrial dysfunction; tumor microenvironment; oxidative phosphorylation; glycolysis; immune evasion; therapeutic strategies; ultrastructural analysis
Online: 21 September 2023 (13:04:57 CEST)
REVIEW
|
doi:10.20944/preprints202404.0054.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
osteoporosis; bone metabolism; proteomics; diagnostic biomarkers; therapeutic targets
Online: 1 April 2024 (17:09:17 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1009.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
multiple sclerosis; therapeutic response; HLA DRB1*0403
Online: 14 August 2023 (10:10:35 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0209.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Aurora kinases; biomarker; kinesins; mitotic defects; prognostic value; Systems Biology; therapeutic targets.
Online: 5 September 2023 (03:48:45 CEST)
REVIEW
|
doi:10.20944/preprints202308.0651.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
cancer; adhesion; metastasis; inhibition; therapeutic approaches; targeted therapies
Online: 9 August 2023 (02:48:16 CEST)
REVIEW
|
doi:10.20944/preprints202403.1011.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
retinoblastoma; RB1; E2F; Targeted Therapy; Therapeutic Vulnerabilities; Spliceosome; Cell Cycle; Epigenetic Regulators; Ubiquitin-Proteasome Pathway
Online: 18 March 2024 (10:29:38 CET)
ARTICLE
|
doi:10.20944/preprints202311.0538.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
[18F]PSMA-1007 PET/CT; [18F]F-Choline PET/CT; prostate; therapeutic management; PSA level; SUVmax
Online: 8 November 2023 (10:30:04 CET)
REVIEW
|
doi:10.20944/preprints202403.1126.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Acute lymphoblastic leukemia (ALL); microbiome; GM; therapeutic strategies
Online: 21 March 2024 (04:25:01 CET)
REVIEW
|
doi:10.20944/preprints202311.0331.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
pleural mesothelioma; treatable traits; novel therapeutic insight; CAR T cells therapy
Online: 7 November 2023 (02:31:14 CET)
REVIEW
|
doi:10.20944/preprints202312.0598.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
NLRP3 inflammasome; comorbidities; pathogenic player; therapeutic potential; rheumatoid arthritis
Online: 8 December 2023 (10:01:25 CET)
SHORT NOTE
|
doi:10.20944/preprints202312.1573.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
radiotherapy; cancer genomics; historical evolution; therapeutic option; cancer treatment
Online: 20 December 2023 (16:00:37 CET)
REVIEW
|
doi:10.20944/preprints202404.0711.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
glioblastoma; CRISPR-based genetic screening; therapy resistance; genetic determinants; therapeutic targets
Online: 10 April 2024 (08:14:36 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0777.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
hypoxic-ischaemic encephalopathy; therapeutic hypothermia; pro-inflammatory biomarkers; cytokines; melatonin; neurodevelopment
Online: 11 April 2024 (07:29:34 CEST)
REVIEW
|
doi:10.20944/preprints202403.1638.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
intestinal microbiota; short-chain fatty acids (SCFAs); dietary fiber fermentation; gastrointestinal and metabolic health; therapeutic implication
Online: 27 March 2024 (06:39:18 CET)
ARTICLE
|
doi:10.20944/preprints202402.1359.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Radiology; Interventional; Bone neoplasms; Metastases; Embolization; Therapeutic; Oncology
Online: 23 February 2024 (09:37:56 CET)
REVIEW
|
doi:10.20944/preprints202404.1000.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Malaria; Telomeres Maintenance; Plasmodium; Therapeutic Target
Online: 16 April 2024 (07:39:39 CEST)
REVIEW
|
doi:10.20944/preprints202308.1577.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Sepsis-associated encephalopathy; Microglial activation; M1/M2 microglial polarization; cognitive impairment; therapeutic strategies
Online: 22 August 2023 (12:09:47 CEST)
REVIEW
|
doi:10.20944/preprints202404.1171.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
clinical trials; evacuated hematoma; meta-analysis; therapeutic hypothermia; traumatic brain in-jury
Online: 17 April 2024 (14:32:27 CEST)
COMMUNICATION
|
doi:10.20944/preprints202404.1453.v2
Subject:
Biochemistry And Molecular Biology,
Biology And Life Sciences
Keywords:
GPER receptor; Therapeutic; Fallopian Tubes; Ovarian Cancer
Online: 24 April 2024 (14:11:35 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0255.v1
Subject:
Endocrinology And Metabolism,
Biology And Life Sciences
Keywords:
diabetes mellitus; type-1 diabetes; risk factors; biomarkers; therapeutic targets; meta-analysis
Online: 6 May 2024 (07:45:46 CEST)