Version 1
: Received: 31 October 2023 / Approved: 31 October 2023 / Online: 1 November 2023 (03:43:47 CET)
How to cite:
Dicks, L. M. T.; Vermeulen, W. Therapeutic Potential of Bacteriophage-derived Proteins. Preprints2023, 2023102086. https://doi.org/10.20944/preprints202310.2086.v1
Dicks, L. M. T.; Vermeulen, W. Therapeutic Potential of Bacteriophage-derived Proteins. Preprints 2023, 2023102086. https://doi.org/10.20944/preprints202310.2086.v1
Dicks, L. M. T.; Vermeulen, W. Therapeutic Potential of Bacteriophage-derived Proteins. Preprints2023, 2023102086. https://doi.org/10.20944/preprints202310.2086.v1
APA Style
Dicks, L. M. T., & Vermeulen, W. (2023). Therapeutic Potential of Bacteriophage-derived Proteins. Preprints. https://doi.org/10.20944/preprints202310.2086.v1
Chicago/Turabian Style
Dicks, L. M. T. and Wian Vermeulen. 2023 "Therapeutic Potential of Bacteriophage-derived Proteins" Preprints. https://doi.org/10.20944/preprints202310.2086.v1
Abstract
Healthcare faces a major problem with the increased emergence of antimicrobial resistance due to the over-prescription of antibiotics. This causes dysbiosis and major disruption of the gut microbiome, leading to the development of intestinal diseases, abnormalities in the regulation of immune responses, malfunctioning of entero-endocrine signaling, and an imbalance in communication with the central nervous system (CNS). Bacteriophages may provide a solution to the treatment of bacterial infections given their specificity. This approach increased rapidly over the last ten years, because of the rapid rise of multi-drug-resistant bacteria worldwide coupled with a decline in the development and production of novel antibacterial agents. Eradication of multidrug-resistant bacteria is often only possible with bacteriophage treatment. Phage proteins are used to stimulate immune responses against specific pathogens, improve antibiotic susceptibility, prevent biofilm formation, and characterize bacterial pathogens. This review discusses the therapeutic potential of bacteriophage-derived proteins.
Biology and Life Sciences, Immunology and Microbiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
