Version 1
: Received: 16 January 2024 / Approved: 17 January 2024 / Online: 17 January 2024 (12:04:26 CET)
How to cite:
Ajaegbu, E.E.; Ikegbuna, C.P. Examining Natural Products with the Potential to Chagas Disease: An In-depth Analysis. Preprints2024, 2024011321. https://doi.org/10.20944/preprints202401.1321.v1
Ajaegbu, E.E.; Ikegbuna, C.P. Examining Natural Products with the Potential to Chagas Disease: An In-depth Analysis. Preprints 2024, 2024011321. https://doi.org/10.20944/preprints202401.1321.v1
Ajaegbu, E.E.; Ikegbuna, C.P. Examining Natural Products with the Potential to Chagas Disease: An In-depth Analysis. Preprints2024, 2024011321. https://doi.org/10.20944/preprints202401.1321.v1
APA Style
Ajaegbu, E.E., & Ikegbuna, C.P. (2024). Examining Natural Products with the Potential to Chagas Disease: An In-depth Analysis. Preprints. https://doi.org/10.20944/preprints202401.1321.v1
Chicago/Turabian Style
Ajaegbu, E.E. and Chizurum Philip Ikegbuna. 2024 "Examining Natural Products with the Potential to Chagas Disease: An In-depth Analysis" Preprints. https://doi.org/10.20944/preprints202401.1321.v1
Abstract
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, stands as a significant public health challenge in endemic regions of the Americas. Current treatment options, limited and associated with adverse effects, underscore the need for novel therapeutic approaches. This systematic review comprehensively examines existing research on natural products as potential agents against Chagas disease. Employing a systematic search strategy across diverse databases, studies meeting predefined inclusion criteria were assessed for methodological quality and relevance. The synthesis of findings reveals a spectrum of natural products showcasing promising anti-Trypanosoma cruzi properties. The review discusses the limitations of current evidence, highlights gaps in knowledge, and proposes avenues for future research. By elucidating the landscape of natural products in Chagas disease treatment, this review contributes to the ongoing pursuit of innovative and accessible therapeutic strategies.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
