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Preprint COMMUNICATION | doi:10.20944/preprints202008.0021.v1

Safe Fieldwork Strategies for At-Risk Individuals

Amelia-Juliette Demery, Monique Pipkin

Subject: Social Sciences, Safety Research Keywords: diversity; inclusion; equity; fieldwork; research

Online: 2 August 2020 (11:55:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201911.0330.v1

Identifying Early-Warning Signals for the Sudden Transition from Mild to Severe Tobacco Rtch Disease by Dynamical Network Biomarkers

Adrián Tarazona, Javier Forment, Santiago F. Elena

Subject: Biology And Life Sciences, Virology Keywords: complex systems; DNB; phase transitions; plant-virus interaction; Potyvirus; protein-protein interaction networks; response to infection; systems biology; Tobacco etch virus

Online: 27 November 2019 (04:42:28 CET)

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Preprint REVIEW | doi:10.20944/preprints202009.0395.v1

V483a – an Emerging Mutation Hotspot of Sars-Cov-2

Omar Ashwaq, Pratibha Manickavasagam, Sk Manirul Haque

Subject: Biology And Life Sciences, Virology Keywords: Spike protein, V483A, substitution mutation, virus-host cell interaction, high transmission, infectivity.

Online: 17 September 2020 (10:43:02 CEST)

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Working Paper ESSAY

Shifting Our Value System Beyond Citations for a More Equitable Future

Sarah Davies, Hollie Putnam, Tracy Ainsworth, Julia Baum, Colleen Bove, Sarah Crosby, Isabelle Côté, Anne Duplouy, Robinson Fulweiler, Alyssa Griffin, Torrance Hanley, Tessa Hill, Adriana Humanes, Sangeeta Mangubhai, Anna Metaxas, Laura Parker, Hanny Rivera, Nyssa Silbiger, Nicola Smith, Ana Spalding, Nikki Traylor-Knowles, Brooke Weigel, Rachel Wright, Amanda Bates

Subject: Social Sciences, Other Keywords: mentorship; citations; bias; sexism; racism; equity; diversity; inclusion; wellbeing

Online: 22 February 2021 (16:17:45 CET)

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Preprint REVIEW | doi:10.20944/preprints202008.0597.v1

An Analysis Review, Detection Coronavirus Disease 2019 (COVID-19) based on Biosensor Application

Bakr Taha, Norhana Arsad, Yousif Al Mashhadany

Subject: Biology And Life Sciences, Virology Keywords: COVID-19 detection; biosensor application; COVID-19 transmission styles; sensors interaction; artificial intelligence

Online: 27 August 2020 (08:01:55 CEST)

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Preprint REVIEW | doi:10.20944/preprints201612.0027.v1

Robots to the Rescue: A Review of Studies on Differential Medical Diagnosis Employing Ontology-Based Chat Bot Technology

Bosede Iyiade Edwards, Idris Oladele Muniru, Adrian David Cheok

Subject: Medicine And Pharmacology, Other Keywords: chatbot technology; ontology-based systems; expert systems; diagnosis; conversational agents; robotics; human-robot interaction; physician-patient relationship; intelligent agents

Online: 6 December 2016 (04:46:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints201912.0028.v1

Diversity-Generated Image Inpainting with Style Extraction

Weiwei Cai, Zhanguo Wei

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: deep learning; generative adversarial networks; image inpainting; diversity inpainting

Online: 3 December 2019 (12:04:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202304.0827.v3

ROSGPT: Next-Generation Human-Robot Interaction with ChatGPT and ROS

Anis Koubaa

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Human-Robot Interaction; ROS; ROS2; ChatGPT; Large Language Model; Robot Operating System

Online: 26 April 2023 (03:54:36 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202005.0097.v5

Why Blood Group A Individuals Are at Risk Whereas Blood Group O Individuals Might Be Protected from SARS-CoV-2 (COVID-19) Infection: A Hypothesis Regarding How the Virus Invades the Human Body via Abo(H) Blood Group-Determining Carbohydrates

Peter Arend

Subject: Biology And Life Sciences, Virology Keywords: COVID-19; SARS-CoV-2–human carbohydrate interaction; trans-species glycosylation; A-like/Tn structure; trans-species glycan bridge

Online: 13 November 2020 (09:42:18 CET)

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Preprint REVIEW | doi:10.20944/preprints202206.0284.v1

Building Consensus around the Assessment and Interpretation of Symbiodiniaceae Diversity

Sarah Davies, Matthew H. Gamache, Lauren I. Howe-Kerr, Nicola G. Kriefall, Andrew C. Baker, Anastazia T. Banaszak, Line K. Bay, Anthony J. Bellantuono, Debashish Bhattacharya, Cheong Xin Chan, Danielle C. Claar, Mary Alice Coffroth, Ross Cunning, Simon K. Davy, Javier del Campo, Erika M. Diaz-Almeyda, Jorg C. Frommlet, Lauren E. Fuess, Raul A. Gonzalez-Pech, Tamar L. Goulet, Kenneth D. Hoadley, Emily J. Howells, Benjamin C. C. Hume, Dustin W. Kemp, Carly, D. Kenkel, Sheila A. Kitchen, Todd C. LaJeunesse, Senjie Lin, Shelby McIlroy, Ryan McMinds, Matthew R. Nitschke, Clinton A. Oakley, Raquel S. Peixoto, Carlos Prada, Hollie M. Putnam, Kate Quigley, Hannah G. Reich, James Davis Reimer, Mauricio Rodriguez-Lanetty, Stephanie Rosalas, Osama S. Saad, Eugenia M. Sampayo, Scott Santos, Eiichi Shoguchi, Edward G. Smith, Michael Stat, Timothy G. Stephens, Marie E. Strader, David J. Suggett, Timothy D. Swain, Cawa Tran, Nikki Traylor-Knowles, Christian R. Voolstra, Mark E. Warner, Virginia M. Weis, Rachel Wright, Tingting Xiang, Hiroshi Yamashita, Maren Ziegler, Adrienne M.S. Correa, John Everett Parkinson

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Symbiodinaceae; genetic diversity; coral symbiosis

Online: 21 June 2022 (04:49:04 CEST)

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Working Paper REVIEW

Bending the Curve of Global Freshwater Biodiversity Loss – An Emergency Recovery Plan

David Tickner, Jeff Opperman, Robin Abell, Mike Acreman, Angela H. Arthington, Stuart E. Bunn, Steven J. Cooke, James Dalton, Will Darwall, Gavin Edwards, Ian Harrison, Kathy Hughes, Tim Jones, David Leclère, Abigail J. Lynch, Philip Leonard, Michael E. McClain, Dean Muruven, Julian D. Olden, Steve Ormerod, Rebecca E. Tharme, Michele Thieme, Klement Tockner, Mark Wright, Lucy Young

Subject: Environmental And Earth Sciences, Ecology Keywords: River restoration; wetlands; freshwater conservation; Sustainable Development Goals; Convention on Biological Diversity

Online: 29 October 2019 (11:13:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints201607.0022.v1

Age-sensitive eHealth Applications in Smart Homes

Wiktoria Wilkowska, Philipp Brauner, Martina Ziefle

Subject: Social Sciences, Psychology Keywords: Ambient Assisted Living; eHealth; Technology Acceptance, Smart Health, User Diversity, Serious Games for Healthcare

Online: 12 July 2016 (09:39:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0481.v1

Methylphenidate and Alprazolam Co-Abuse: Drug-DNA Interactions

Shweta Sharma, Meenu Dutt, Neha Sharma, Ravinder Naik Dharavath, Tanzeer Kaur

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Drug-DNA interaction; FTIR; Polydrug-abuse; UV-visible spectrophotometer

Online: 23 October 2020 (10:36:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202301.0521.v1

Feasibility Study on Utilization of the Artificial Intelligence GPT-3 in Public Health

David Jungwirth, Daniela Haluza

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: ChatGPT; GPT-3; OpenAI; chatbots; digital health; artificial intelligence; automation; technological advancement; human-AI interaction; collaboration; open science

Online: 28 January 2023 (07:56:35 CET)

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Preprint REVIEW | doi:10.20944/preprints202004.0359.v1

Genomic Diversity and Evolution, Diagnosis, Prevention, and Therapeutics of the Pandemic COVID-19 Disease

M. Nazmul Hoque, Abed Chaudhury, Md. Abdul Mannan Akanda, M. Anwar Hossain, Md Tofazzal Islam

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: SARS-CoV-2; genetic diversity; genome evolution; diagnostics; therapeutics; vaccines

Online: 20 April 2020 (02:33:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201709.0030.v2

Extended Dynamical Equations of the Period Vectors of Crystals under Constant External Stress to Many-body Interactions

Gang Liu

Subject: Physical Sciences, Condensed Matter Physics Keywords: dynamical equation; crystal; period vectors; periodic structure; period dynamics; pressure; stress; many-body interaction; molecular dynamics; periodic boundary conditions

Online: 9 August 2018 (08:36:53 CEST)

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Preprint REVIEW | doi:10.20944/preprints202101.0236.v1

Facing Racism and Sexism in Science by Fighting against Social Implicit Bias: A Latin and Black Woman Perspective.

Karin Calaza, Fatima Erthal, Mirtes Pereira, Kita Macario, Veronica Daflon, Isabel David, Helena Castro, Maria Vargas, Laura Martins, Jasmin Stariolo, Eliane Volchan, Leticia Oliveira

Subject: Social Sciences, Psychology Keywords: implict bias; gender disparity; diversity; racial dispariry

Online: 12 January 2021 (17:51:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0114.v1

A Possible Role of an Interaction of the Age at Common Childhood Infections and Selected Dietary Factors at Young Age, for the Risk of Multiple Sclerosis

Klaus Lauer, Annette Wahl, Marcel Geilenkeuser

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: multiple sclerosis; epidemiology; diet; childhood infections; interaction

Online: 22 November 2016 (13:00:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0008.v1

Raman and Terahertz Spectroscopic Investigation of Cocrystal Formation Involving Antibiotic Nitrofurantoin Drug and Coformer 4-aminobenzoic Acid

Yong Du, Qiang Cai, Jiadan Xue, Qi Zhang

Subject: Medicine And Pharmacology, Pharmacy Keywords: nitrofurantoin; active pharmaceutical ingredient; 4-aminobenzoic acid; cocrystallization; intermolecular interaction; Raman spectroscopy; terahertz spectroscopy

Online: 1 November 2016 (09:54:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0198.v1

Conformational Flexibility and the Interaction of Huperzine A in the Active Site of Acetylcholinesterase: A Quantum Chemical and Charge Density Study

Renuga Parameswari Azhagesan, Saravanan Kandasamy, Kumaradhas Poomani

Subject: Chemistry And Materials Science, Theoretical Chemistry Keywords: huperzine A-AChE; molecular docking; intermolecular interaction; quantum chemical calculation; charge density distribution; atomic charges; dipole moment; electrostatic potential; toxicity analysis

Online: 23 August 2016 (12:33:27 CEST)

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Preprint REVIEW | doi:10.20944/preprints201701.0122.v1

Synergy Effects in the Chemical Synthesis and Extensions of Multicomponent Reactions (MCRs)—The Low Energy Way to Ultra-Short Syntheses of Tailor-Made Molecules

Heiner Eckert

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: multicomponent reaction; MCR; post condensation modification PCM; post condensation cyclisation PCC; MFCR; multifunction catalysis; variability; diversity; complexity; efficiency of synthesis

Online: 26 January 2017 (10:04:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints201906.0050.v1

Avicenna’s Ideas and Arguments about Mind and Brain Interaction

Mohammad Jamali, Mehdi Golshani, Yousef Jamali

Subject: Arts And Humanities, Philosophy Keywords: mind brain interaction, Avicenna, consciousness, cognition, incorporeity of mind, mind matter interaction

Online: 6 June 2019 (12:58:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0005.v1

Evaluation of Soil-Structure Interaction on the Seismic Response of Liquid Storage Tanks under Earthquake Ground Motions

Mostafa Farajian, Mohammad Iman Khodakarami, Denise-Penelope N. Kontoni

Subject: Engineering, Civil Engineering Keywords: liquid storage tanks; soil-structure interaction; seismic response; earthquake ground motions

Online: 1 December 2016 (10:36:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0056.v1

Experimental Investigation of Mechanical Properties of Black Shales after CO₂-Water-Rock Interaction

Qiao Lyu, P.G. Ranjith, Xinping Long, Bin Ji

Subject: Engineering, Civil Engineering Keywords: shale; CO2-water-rock interaction; mechanical properties; crack propagation; microstructure

Online: 5 August 2016 (12:35:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0102.v2

Computational Investigation on Various Small Array Dispositions of Generic Points Absorbers

Lorenzo Baños Hernandez

Subject: Engineering, Energy And Fuel Technology Keywords: ocean wave energy; fluid-structure interaction; BEM; diffraction/ radiation; floating cylinder; heave; array

Online: 14 June 2017 (05:47:27 CEST)

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This thesis completion works it out to deepen into diverse modeling techniques for Point Absorbers. A combined frequency-time domain model is conceived, designed and developed in Matlab with FoRtran as a base., leading to obtain physical variables of primary importance, namely position, velocity and power to Energy net balance relationships of absorption. Integration of different degrees of freedom with heave as main executable leads in turn to a single buoy motion focus. Acquisition of the needed hydrodynamic coefficients is provided though application of NEMOH & BEMIO solvers due to the Boundary Element Methodology. Initially, this Wave-to-motion model is validated through comparison with previous experimental results for a floating cone cylinder shape (Buldra-FO3). A single, generic, vertical floating cylinder is contemplated then, that responds to the action of the passing regular waves excitation. Later, two equally sized vertical floating cylinders aligned with the incident wave direction are modeled for a variable distance between the bodies. For both unidirectional regular and irregular waves as an input in deep water, we approximate the convolutive radiation force function term through the Prony method. By changing the spatial disposition of the axisymmetric buoys, using for instance triangular or rectangular shaped arrays of three and four bodies respectively, the study delves into motion characteristics for regular waves. The results highlight efficient layouts for maximizing the energy production whilst providing important insights into their performance, revealing displacement amplification- and capture width-ratios, while deriving in possible interpretations of scenarios related to the the known park effect. These terms are encompassed by the novelty of a new conceptual Post-Processing methodology in the field, which leads to obtain an optimal distance for the separated bodies with effective energy absorption in a regular wave regime. In conclusion, this computational excursion envisions and proposes potentials fields of study, which will surely enhance new connections and link this renewable energy form.

Preprint ARTICLE | doi:10.20944/preprints201704.0035.v2

Higher Ocean Wind Speeds During Marine Cold Air Outbreaks

Erik W. Kolstad

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Cold air outbreaks; Air–sea interaction; Polar climate; Wind speed; polar lows

Online: 2 May 2017 (17:45:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201702.0052.v1

Simplified Swarm Optimization Based Function Modules Detection in Protein-to-Protein Interaction Networks

Xianghan Zheng, Lingting Wu, Shaozhen Ye, Riqing Chen

Subject: Computer Science And Mathematics, Information Systems Keywords: protein–protein interaction networks; protein function module; simplified swarm optimization

Online: 15 February 2017 (10:17:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0076.v5

The Spin-Spin Interaction Mechanism between Quarks and Its Impact on the Mass Spectrum of Mesons

Engel Roza

Subject: Physical Sciences, Particle And Field Physics Keywords: quarks; spin-spin interaction; hadronization limit; topquark; eta-etaprime puzzle; mass spectrum

Online: 17 January 2022 (15:49:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0097.v1

Structural Equation Model into Interaction Mechanism between Forest Industry and Ecology with Environmental Mediator Introduced

Bing Liao, Zhiguang Zhang, Chunxiang Liu, Yuanzheng Wu

Subject: Business, Economics And Management, Economics Keywords: forest industry and ecology; environmental capacity; interaction mechanism; SEM; PSIR

Online: 18 November 2016 (10:01:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0131.v1

Comparing the Incomparable: ‘Speaking Out’ and the Use of Drawings in Notebooks by Physicists

Harmen Hollestelle

Subject: Arts And Humanities, Philosophy Keywords: physicists, experimental set-up, drawings, spirituality, interaction

Online: 28 December 2016 (10:24:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints201907.0326.v2

Demonstration to Unify 4 Interactions in Particle Physics with the Zero‐Point Energy and Quantized Spacetime

Shinichi Ishiguri

Subject: Physical Sciences, Particle And Field Physics Keywords: zero‐point energy; quantized spacetime; static electromagnetic field; gravity field; weak interaction; strong interaction; masses of W and Z; β collapse; quantized Einstein gravity equation

Online: 9 November 2023 (13:40:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0135.v1

Evolution of Serum 25OHD in Response to Vitamin D₃ Fortified-Yogurts Consumed by Healthy Menopausal Women: A Six-Month Randomized-Controlled Trial Assessing the Interactions between Doses, Baseline Vitamin D Status and Seasonality

Jean-Philippe Bonjour, Flore Dontot-Payen, Emilien Rouy, Stephane Walrand, Brigitte Rousseau

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: nutritional intervention; menopausal women; vitamin D3-fortified yogurts; serum 25OHD dose response; seasonality interaction

Online: 31 January 2017 (12:01:31 CET)

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Preprint REVIEW | doi:10.20944/preprints201708.0093.v1

Omics in Aid of Host-pathogen Interaction Studies: A Bacterial Perspective

Ursula Fels, Kris Gevaert, Petra Van Damme

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: bacterial pathogens; host-pathogen interaction; infection biology; omics

Online: 27 August 2017 (11:18:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0116.v1

Evaluation of Diversification Techniques for Legal Information Retrieval

Marios Koniaris, Ioannis Anagnostopoulos, Yannis Vassiliou

Subject: Computer Science And Mathematics, Information Systems Keywords: diversity; algorithms; legal information retrieval

Online: 23 November 2016 (09:50:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202105.0607.v2

Gravitational-Magnetic-Electric Interaction in Controlling Relative Permittivity and Permeability

Yin Zhu

Subject: Physical Sciences, Particle And Field Physics Keywords: Gravitational-electric-magnetic interaction; Controlling permittivity and permeability; Superconductivity

Online: 13 September 2021 (12:31:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints202004.0333.v1

Visiting Bitter Gourd (Momordica charantia) from a Breeding Perspective: A Review

Hari Kesh, Prashant Kaushik

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: bitter gourd; breeding; genetic diversity; genomics; heterosis; molecular breeding; mutation breeding

Online: 19 April 2020 (06:00:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201711.0166.v1

SWOT Analysis for Architectural and Structural Solutions Interaction Assessment in High-Rise Buildings Design

Jolanta Tamošaitienė, Ernestas Gaudutis

Subject: Engineering, Civil Engineering Keywords: high-rise buildings; architecture; structural solutions; interaction; SWOT analysis

Online: 26 November 2017 (12:45:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0026.v1

From Systems to Organisations

Maurício Kritz

Subject: Biology And Life Sciences, Other Keywords: system structure; organised complexity; organisation; models of organisation; whole-part graphs; synexions; organised sets; organisation interaction; in-formation

Online: 3 November 2016 (10:41:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202110.0172.v1

The Effect of Productive Safety Net Programme on Household Food Consumption and Dietary Diversity in Ethiopia

Mebratu Feyisa

Subject: Business, Economics And Management, Economics Keywords: PSNP; household food consumption; household dietary diversity; random effect; instrumental variable

Online: 11 October 2021 (17:15:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201705.0145.v1

Spatial Pattern Dynamics Analysis in Coastal Area Using Spatial Metric in Pekalongan, Indonesia

Ali Wijaya, Cahyono Susetyo, Azillatin Q. Diny, Danika H. Nabila, Rahel P. Pamungkas, Mohammad Hadikunnuha, Nursakti A. Pratomoatmojo

Subject: Environmental And Earth Sciences, Environmental Science Keywords: spatial pattern; land use; spatial metric; aggregation; diversity

Online: 19 May 2017 (08:43:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0203.v1

Interaction of Gravitational Field and Orbit in Sun-planet-moon system

Yin Zhu

Subject: Physical Sciences, Acoustics Keywords: Interaction of gravitational field; Three-body problem; Orbital perturbation theory; Repulsive gravity; Neutralization of gravity

Online: 10 May 2021 (14:49:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201801.0111.v1

Applicability of Precision Medicine Approaches to Managing Hypertension in Rural Populations

Jacqueline R. Halladay, Kaitlin C. Lenhart, Kimberly Robasky, Wendell Jones, Wayne F. Homan, Doyle M. Cummings, Crystal W. Cené, Alan L. Hinderliter, Cassandra L. Miller, Katrina E. Donahue, Beverly A. Garcia, Thomas C. Keyserling, Alice S. Ammerman, Cam Patterson, Darren A. DeWalt, Larry F. Johnston, Monte S. Willis, Jonathan C. Schisler

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: hypertension; GWAS; precision medicine; rural population; SNP-age interaction

Online: 12 January 2018 (07:34:37 CET)

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Background: As part of the Heart Healthy Lenoir Project, we developed a practice level intervention to improve blood pressure control. The goal of this study was: i) determine if single nucleotide polymorphisms (SNPs) that associate with blood pressure variation, identified in large case-control studies, are applicable to blood pressure control in subjects from a rural population; ii) measure the association of these SNPs with subjects’ responsiveness to the hypertension intervention; and iii) identify other SNPs that may help understand patient-specific responses to an intervention. Methods and Results: We used a combination of candidate SNPs and genome-wide analyses to test associations with either baseline systolic blood pressure (SBP) or change in systolic blood pressure one year after the intervention in two genetically defined ancestral groups: African Americans (AA) or Caucasian Americans (CAU). Of the 48 candidate SNPs, 13 SNPs associated with baseline SBP in our study; however, one candidate SNP, rs592582, also associated with a change in SBP after one year. Using our study data, we identified 4 and 15 additional loci that associated with a change in SBP in the AA and CAU groups, respectively. Our analysis of gene-age interactions identified genotypes associated with SBP improvement within different age groups of our populations. Moreover, our integrative analysis identified AQP4-AS1 and PADI2 as genes whose expression levels may contribute to the pleiotropy of complex traits involved in cardiovascular health and blood pressure regulation in response to an intervention targeting hypertension. Conclusions: Identification of SNPs associated with the success of a hypertension treatment intervention suggests that genetic factors in combination with age may contribute to an individual’s success in lowering SBP. If these findings prove to be applicable to other populations, the use of this genetic variation in making patient-specific interventions may help providers with making decisions to improve patient outcomes. Further investigation is required to determine the role of this genetic variance with respect to the management of hypertension such that more precise treatment recommendations may be made in the future as part of personalized medicine.

Preprint CONCEPT PAPER | doi:10.20944/preprints202011.0342.v1

You are Welcome Here: Considerations of Diversity, Equity, and Inclusion for Embracing New Ecologists

Bonnie M. McGill, Madison J. Foster, Abagael N. Pruitt, Samantha Gabrielle Thomas, Emily R. Arsenault, Janaye Hanschu, Kynser Wahwahsuck, Evan Cortez, Kaci Zarek, Terrance D. Loecke, Amy J. Burgin

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: Undergraduate research experience; diversity; equity; inclusion; science communication

Online: 12 November 2020 (11:31:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints201711.0114.v1

Hydrochemical Characteristics and Multivariate Statistical Analysis of Natural Water System: A Case Study in Kangding County, Southwestern China

Yunhui Zhang, Mo Xu, Xiao Li, Jihong Qi, Qiang Zhang, Jian Guo, Leilei Yu, Rui Zhao

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Hydrochemcial characteristics; water-rock interaction; multivariate statistical analysis; mixing model; δD and δ18O isotopes; natural water system; Kangding County

Online: 17 November 2017 (12:34:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints201705.0149.v1

Spatial Pattern Dynamics Analysis at Coastal Area Using Spatial Metric in Pekalongan, Indonesia

Ali Wijaya, Cahyono Susetyo, Azillatin Qisthian Diny, Danika Hudani Nabila, Rahel Putri Pamungkas, Mohammad Hadikunnuha, Nursakti Adhi Pratomoatmojo

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Spatial Pattern; Land Use; Spatial Metric; Aggregation; Diversity

Online: 19 May 2017 (16:21:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201902.0232.v1

Demonstration of Bomb Detection Using the IBM Quantum Computer

Ankit Raj, Barnali Das, Bikash K. Behera, Prasanta K. Panigrahi

Subject: Physical Sciences, Quantum Science And Technology Keywords: Bomb Detection; Interaction Free Measurement; Mach Zhender Interferometer; IBM Quantum Expeience

Online: 25 February 2019 (15:23:20 CET)

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Preprint REVIEW | doi:10.20944/preprints202010.0149.v1

Advances in Melon Breeding (Cucumis melo L.): An Update

Hari Kesh, Prashant Kaushik

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: breeding; diversity; genetic engineering; genomics; male sterility; melon; QTLs

Online: 7 October 2020 (09:22:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201901.0160.v2

Flow-Induced Stresses and Displacements in Jointed Concrete Pipes, Installed by Pipe Jacking Method

Moses Karakouzian, Mehrdad Karami, Mohammad Nazari-Sharabian, Sajjad Ahmad

Subject: Engineering, Civil Engineering Keywords: fluid-structure interaction; soil-structure interaction; transient flow; pipe jacking; numerical modeling; abaqus FEA

Online: 17 January 2019 (05:02:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints201906.0275.v1

Untargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models

David Licha, Silvia Vidali, Sepideh Aminzadeh-Gohari, Oliver Alka, Leander Breitkreuz, Oliver Kohlbacher, Roland Reischl, Roland Feichtinger, Barbara Kofler, Christian G. Huber

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: ketogenic diet; breast cancer; xenograft; untargeted metabolomics; HPLC-MS; reversed phase chromatography; hydrophilic interaction liquid chromatography

Online: 27 June 2019 (05:35:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201908.0244.v1

Commenting on Top Spanish YouTubers: “No Comment”

Victoria Tur-Viñes, Araceli Castelló-Martínez

Subject: Social Sciences, Behavior Sciences Keywords: YouTubers; sentiment analysis; interaction; influencers; commenting; Facebook

Online: 23 August 2019 (10:23:31 CEST)

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Preprint REVIEW | doi:10.20944/preprints201705.0071.v1

Neurophysiological Changes Induced by Chronic Toxoplasma gondii Infection

Ellen Tedford, Glenn McConkey

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: Toxoplasma gondii; neurophysiology; host-parasite interaction, neuroimmune, testosterone, dopamine, catecholamine, glutamatergic

Online: 8 May 2017 (18:34:39 CEST)

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Preprint REVIEW | doi:10.20944/preprints201906.0022.v1

Pursuing the potential of heirloom cultivars to improve adaptation, nutritional and culinary features in a changing climate

Sangam Dwivedi, Irwin Goldman, Rodomiro Ortiz

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: culinary and nutritional traits; farmer-breeder-chef-consumer nexus; folk cultivars; genetic diversity; global warming; heritage seedbank; local food systems; seed savers; stress tolerance

Online: 3 June 2019 (12:34:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201711.0079.v1

Cryptic Species Diversity of Rice Hopper Parasitoids in Southeast Asia

Christina Sann, Franziska Wemheuer, Alexis Beaurepaire, Rolf Daniel, silvio Erler, Stefan Vidal

Subject: Biology And Life Sciences, Insect Science Keywords: DNA barcoding; genetic diversity; hymenopteran parasitoids; Nephotettix spp.; Nilaparvata lugens; rice

Online: 13 November 2017 (17:06:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints201707.0047.v1

Genetic Structure and Eco-Geographical Differentiation of Wild Sheep Fescue (Festuca ovina L.) in Xinjiang, Northwest China

Chenglin Zhang, Jianbo Zhang, Yan Fan, Ming Sun, Wendan Wu, Wenda Zhao, Xiaopeng Yang, Linkai Huang, Yan Peng, Xiao Ma, Xinquan Zhang

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Festuca ovina L.; AFLP, genetic diversity; genetic barriers; environmental factors

Online: 18 July 2017 (10:05:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202001.0060.v1

Doubling the Accuracy of Indoor Location: Frequency Diversity

Berthold Horn

Subject: Engineering, Electrical And Electronic Engineering Keywords: indoor location; fine time measurement; round trip time; FTM; RTT; IEEE 802.11mc; IEEE 802.11-2016; time diversity; spatial diversity; bandwidth diversity; frequency diversity; Bayesian grid; observation model; transition model

Online: 8 January 2020 (04:18:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0366.v1

Does Islam Practice Tolerance? Some Notes from Quranic Perspective

Abur Hamdi Usman

Subject: Social Sciences, Religion Keywords: Tolerance; Religion; Islam; Society; Diversity

Online: 19 July 2018 (15:43:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202301.0474.v1

Artificial Intelligence and Ten Societal Megatrends: A GPT-3 Case Study

Daniela Haluza, David Jungwirth

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: ChatGPT; GPT-3; global trends; OpenAI; chatbots; digital health; artificial intelligence; automation; technological advancement; human-AI interaction; collaboration

Online: 26 January 2023 (08:37:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints201801.0211.v1

Membranes: A Variety of Energy Landscapes for Many Transfer Opportunities

Patrice Bacchin

Subject: Physical Sciences, Chemical Physics Keywords: membrane transport; osmosis; interaction

Online: 23 January 2018 (06:43:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0303.v1

The Strawberry Line’s Breeding Birds and their Biophilic Benefits (Vale of Winscombe Section)

Lincoln Garland

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: Breeding birds; bird diversity; birdsong; biophilic; mental wellbeing; Nature’s Fix; Strawberry Line; Vale of Winscombe; Mendip Hills

Online: 13 September 2020 (23:51:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201901.0242.v2

First-Principles Prediction of Skyrmionic Phase Behavior in GdFe$_2$ Films Capped by 4$D$ and 5$D$ Transition Metals

Soyoung Jekal, Andreas Danilo, Dao Phoung, Xiao Zheng

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: skyrmion; Dzyaloshinskii–Moriya interaction; exchange energy; magnetic anisotropy

Online: 13 February 2019 (10:33:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0063.v1

A Method for Analysis and Visualization of Similar Hotspot Flow Patterns between Different Regional Groups

Haiping Zhang, Xingxing Zhou, Xin Gu, Genlin Ji, Guoan Tang

Subject: Environmental And Earth Sciences, Space And Planetary Science Keywords: regional group interaction; similar hotspot flow patterns; spatial interaction; visual analytics; Geo-Information-Tupo; GIS

Online: 4 July 2018 (09:26:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201906.0019.v2

Mathematical Basis for the Assessment of Antibiotic Resistance and Administrative Counter-Strategies

Hans H. Diebner, Anna Kather, Ingo Roeder, Katja de With

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: antibiotic cycling; antibiotic mixing; antibiotic resistance; diversity; entropy; heterogeneity

Online: 27 August 2020 (08:03:07 CEST)

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Diversity as well as temporal and spatial changes of the proportional abundances of different antibiotics (cycling, mixing or combinations thereof) have been hypothesised to be an effective administrative control strategy in hospitals to reduce the prevalence of antibiotic-resistant pathogens in nosocomial or community-acquired infections. However, a rigorous assessment of the efficacy of these control strategies is lacking. The main purpose here is to present a mathematical framework for the assessment of control stategies from a processual stance. To this end, we adopt diverse measures of heterogeneity and diversity of proportional abundances based on the concept of entropy from other fields and adapt them to the needs in assessing the impact of variations in antibiotic consumption on antibiotic resistance. Thereby, we derive a family of diversity measures whose members exhibit different degrees of complexity. Most important, we extent these measures such that they account for the assessment of temporal changes in heterogeneity including otherwise undetected diversity-invariant permutations of antibiotics consumption and prevalence of resistant pathogens. We apply a correlation analysis for the assessment of associations between changes of heterogeneities on the antibiotics and on the pathogen side. As a showcase, which serves as a proof-of-principle, we apply the derived methods to records of antibiotic consumption and prevalence of antibiotic-resistant germs from University Hospital Dresden. Besides the quantification of heterogeneities of antibiotics consumption and antibiotic resistance, we show that a reduction of prevalence of antibiotic-resistant germs correlates with a temporal change of similarity with respect to the first observation of antibiotics consumption, although heterogeneity remains approximately constant. Although an interventional study is pending, our mathematical framework turns out to be a viable concept for the assessment and optimisation of control strategies intended to reduce antibiotic resistance.

Preprint ARTICLE | doi:10.20944/preprints201902.0018.v2

Comparing Measures of Community Lineage Diversity across North American Forests

Kyle G. Dexter, Ricardo A. Segovia, Andy Griffiths

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: temperate forests; species richness; lineage diversity; phylogenetic diversity; United States; trees; TILD

Online: 13 February 2019 (10:15:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints201801.0247.v1

Species Diversity of Oak Stands and Its Significance for Drought Resistance

Jan Kotlarz, Sylwia Nasiłowska, Karol Rotchimmel, Katarzyna Kubiak

Subject: Environmental And Earth Sciences, Environmental Science Keywords: drought; diversity; oaks; remote sensing

Online: 26 January 2018 (04:52:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202105.0227.v2

Theoretical Derivation of Critical Current Density and Critical Magnetic Field Considering Many-Body Interactions of Magnetic Flux Quanta

Shinichi Ishiguri

Subject: Physical Sciences, Condensed Matter Physics Keywords: vortices; vortex physics; critical temperature; magnetic flux quantum; critical current density; critical magnetic field; many-body interaction

Online: 4 August 2022 (08:51:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202006.0323.v1

Understanding Inclusion within Diversity: Meaning, Model, and Practice

Kaja Brix, Olivia Lee, Sorina Stalla

Subject: Social Sciences, Sociology Keywords: diversity and inclusion; science; social pain; theory of inclusion; framework model of inclusion; practice of inclusion; meaning of inclusion

Online: 28 June 2020 (08:50:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201709.0094.v1

Modeling Link for Ocean Wave Energy of Point Absorbers: A Mathematical Framework

Lorenzo Baños Hernandez

Subject: Engineering, Marine Engineering Keywords: ocean wave energy; fluid-structure interaction; BEM; diffraction/ radiation; floating cylinder; heave; array

Online: 20 September 2017 (05:42:49 CEST)

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This compendium presents new mathematical techniques for modeling Point Absorbers. A combined frequency-time domain framework is developed. It is used to simulate the energy generated by the wave farms. With Matlab and Fortran as a base, this leads to obtain physical variables of primary importance, namely position, velocity and power to energy net balance relationships of absorption. Integration of different degrees of freedom with heave as main executable leads in turn to a single buoy motion focus. Acquisition of the needed hydrodynamic coefficients is provided through application of potential field solvers with Boundary Element Methodology background. Initially, this Wave-to-motion model is validated by comparison with previous experimental results for a floating cone cylinder shape (Buldra-FO3). A single, generic, vertical floating cylinder is contemplated then, that responds to the action of the passing regular waves excitation. Later, two equally sized vertical floating cylinders aligned with the incident wave direction are modeled for a variable distance between the bodies. For both unidirectional regular and irregular waves as an input in deep water, we approximate the convolutive radiation force function term through the Prony method. By changing the spatial disposition of the axisymmetric buoys, using for instance triangular or rectangular shaped arrays of three and four bodies respectively, the study delves into motion characteristics for regular waves. The results highlight efficient layouts for maximizing the energy production whilst providing important insights into their performance, revealing displacement amplification- and capture width-ratios, while deriving in possible interpretations of scenarios related to the known park effect. These terms are encompassed by the novelty of a new conceptual Post-Processing methodology in the field, which leads to obtain an optimal distance for the separated bodies with effective energy absorption in a regular wave regime. The main objective is to generate a tendency within the hydrodynamic field of study, which is the Wave to motion perspective. More generally, this computational excursion envisions and depicts potential fields of study, which will surely enhance new connections and link this renewable energy form. Therefore, this research delves first into the historical and technical background on Ocean Wave Energy. Next, it is in the section regarding Materials and Methods, where boundaries and related equations are introduced step by step, together with latter mentioned case scenarios, and their corresponding configuration parameters. A separate section frames then the scope of results, while finally, there is an ensuing discussion and conclusions for evaluation assessment.

Preprint REVIEW | doi:10.20944/preprints201812.0094.v1

Potentials of the Underutilized Kei-apple (Dovyalis caffra L.): Beyond its Nutritional and Functional Value

Abiodun Olusola Omotayo, Khayelihle Ncama, Adeyemi Oladapo Aremu

Subject: Biology And Life Sciences, Food Science And Technology Keywords: economic sustainability; environment conservation; food security; income diversity; indigenous fruit.

Online: 7 December 2018 (17:15:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202004.0480.v1

The Minimum Information about a Molecular Interaction Causal Statement (MI2CAST)

Vasundra Touré, Steven Vercruysse, Marcio Luis Acencio, Ruth Lovering, Sandra Orchard, Glyn Bradley, Cristina Casals-Casas, Claudine Chaouiya, Noemi del-Toro, Åsmund Flobak, Pascale Gaudet, Henning Hermjakob, Luana Licata, Astrid Lægreid, Christopher Mungall, Anne Niknejad, Simona Panni, Livia Perfetto, Pablo Porras, Dexter Pratt, Denis Thieffry, Paul Thomas, Dénes Türei, Julio Saez-Rodriguez, Martin Kuiper

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: causal statement; causal interaction; directed molecular interaction; minimum information; standardization, systems biology

Online: 27 April 2020 (05:07:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201712.0058.v1

Interactive Hesitation Synthesis and Its Evaluation

Simon Betz, Birte Carlmeyer, Petra Wagner, Britta Wrede

Subject: Social Sciences, Language And Linguistics Keywords: speech synthesis; evaluation; hesitation; virtual agents; interaction

Online: 11 December 2017 (07:03:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202007.0439.v1

Factors influencing Local Community Participation in Wildlife Conservation Projects in Northeast India

Sayan Banerjee, Ambika Aiyadurai

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Participation; Wildlife; Community–Based Conservation; India; Interaction; Northeast India

Online: 19 July 2020 (20:42:21 CEST)

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Working Paper HYPOTHESIS

Human Genetic Diversity Possibly Determines Human's Compliance to COVID-19

Yiqiang Zhao, Yunchun Gu, Yongji Liu, Sa Li, Yuzhan Wang, Lina Bu, Qi Liu, Hongyi Lv, Fang Wan, Lida Wu, Zemin Ning

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: COVID-19; severe symptoms; inactivation; genetic diversity

Online: 16 April 2020 (09:15:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202101.0440.v1

Comprehensive Identification of Glycosphingolipids in Human Plasma using Hydrophilic Interaction Liquid Chromatography – Electrospray Ionization Mass Spectrometry

Michal Holčapek, Karel Hořejší, Robert Jirásko, Michaela Chocholoušková, Denise Wolrab, David Kahoun

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: glycosphingolipids; lipidomics; mass spectrometry; hydrophilic interaction liquid chromatography; human plasma; lipid profile; sample preparation; fragmentation behavior

Online: 22 January 2021 (11:31:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202101.0173.v1

Molecular Epidemiology Surveillance of SARS-Cov-2: Mutations and Genetic Diversity One Year After Emerging

Alejandro Flores-Alanis, Armando Cruz-Rangel, Flor Rodríguez-Gómez, James González, Carlos Alberto Torres-Guerrero, Gabriela Delgado, Alejandro Cravioto, Rosario Morales-Espinosa

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: SARS-CoV-2; genetic diversity; molecular surveillance; natural selection; non-synonymous substitution

Online: 11 January 2021 (09:50:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints201904.0205.v1

Preactivation Crosslinking – An Efficient Method for the Oriented Immobilization of Antibodies

Barbara Schroeder, Hoa Le Xuan, Jule L. Völzke, Michael G. Weller

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: antibody coating; proximity-enhanced reaction; immunoglobulins; IgG; protein A; protein G; bio-interaction; immunoprecipitation; pull-down assay; immunocapture; stabilization; yield; regeneration; nanoparticles; microparticles; biochips; immunosensor; photochemical crosslinker; click chemistry; herceptin; trastuzumab

Online: 18 April 2019 (07:55:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201904.0321.v1

Whole Genome Diversity, Population Structure and Linkage Disequilibrium Analysis of Chickpea (Cicer arietinum L.) Genotypes Using Genome-Wide DArTseq-Based SNP Markers

Somayeh Farahani, Mojdeh Maleki, Rahim Mehrabi, Homayoun Kanouni, Reza Talebi

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: chickpea; genetic diversity; linkage disequilibrium; DArTseq-SNP markers

Online: 29 April 2019 (07:56:52 CEST)

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Characterization of genetic diversity, population structure and linkage disequilibrium is prerequisite for proper management of breeding programs and conservation of genetic resources. In this study, 186 chickpea genotypes including advanced “Kabuli” breeding lines and Iranian landrace “Desi” chickpea genotypes were genotyped using DArTseq-Based SNP markers. Out of 3339 SNPs, 1152 markers with known chromosomal position were selected for genome diversity analysis. The number of mapped SNP markers varied from 52 (LG8) to 378 (LG4), with an average of 144 SNPs per linkage group. The chromosome size that covered by SNPs varied from 16236.36 kbp (LG8) to 67923.99 kbp (LG5), while LG4 showed higher number of SNPs, with an average of 6.56 SNPs per Mbp. Polymorphism information content (PIC) value of SNP markers ranged from 0.05 to 0.50, with an average of 0.32, while the markers on LG4, LG6 and LG8 showed higher mean PIC value than average. Un-weighted Neighbor Joining cluster analysis and Bayesian-based model population structure grouped chickpea genotypes into four distinct clusters. Principal component analysis (PCoA) and Discriminant Analysis of Principal Component (DAPC) results were consistent with that of the cluster and population structure analysis. Linkage disequilibrium (LD) was extensive and LD decay in chickpea germplasm was relatively low. A few markers showed r²≥0.8, while 2961 pairs of markers showed complete LD (r²=1) and a huge LD block was observed on LG4. High genetic diversity and low kinship value between pairs of genotypes suggesting the presence of a high genetic diversity among studied chickpea genotypes. This study also demonstrated the efficiency of DArTseq-based SNP genotyping for large scale genome analysis in chickpea. The genotypic markers provided in this study are useful for various association mapping studies when combined with phenotypic data of different traits such as seed yield, abiotic and biotic stresses and therefore can be efficiently used in breeding programs to improve chickpea.

Preprint ARTICLE | doi:10.20944/preprints201708.0025.v1

Comparative Framework Linking Some Capabilities of Small Array Dispositions of Generic Points Absorbers

Lorenzo Baños Hernandez

Subject: Engineering, Marine Engineering Keywords: ocean wave energy; fluid-structure interaction; BEM; diffraction/ radiation; floating cylinder; heave; array

Online: 7 August 2017 (16:31:44 CEST)

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This thesis completion works it out to deepen into diverse modeling techniques for Point Absorbers. A combined frequency-time domain model is conceived, designed and developed in Matlab with Fortran as a base, leading to obtain physical variables of primary importance, namely position, velocity and power to energy net balance relationships of absorption. Integration of different degrees of freedom with heave as main executable leads in turn to a single buoy motion focus. Acquisition of the needed hydrodynamic coefficients is provided through application of NEMOH \& BEMIO solvers due to the Boundary Element Methodology. Initially, this Wave-to-motion model is validated by comparison with previous experimental results for a floating cone cylinder shape (Buldra-FO3). A single, generic, vertical floating cylinder is contemplated then, that responds to the action of the passing regular waves excitation. Later, two equally sized vertical floating cylinders aligned with the incident wave direction are modeled for a variable distance between the bodies. For both unidirectional regular and irregular waves as an input in deep water, we approximate the convolutive radiation force function term through the Prony method. By changing the spatial disposition of the axisymmetric buoys, using for instance triangular or rectangular shaped arrays of three and four bodies respectively, the study delves into motion characteristics for regular waves. The results highlight efficient layouts for maximizing the energy production whilst providing important insights into their performance, revealing displacement amplification- and capture width-ratios, while deriving in possible interpretations of scenarios related to the the known park effect. These terms are encompassed by the novelty of a new conceptual Post-Processing methodology in the field, which leads to obtain an optimal distance for the separated bodies with effective energy absorption in a regular wave regime. In conclusion, this computational excursion envisions and proposes potential fields of study, which will surely enhance new connections and link this renewable energy form.

Preprint REVIEW | doi:10.20944/preprints201712.0052.v1

Programming of Cell Resistance to Genotoxic and Oxidative Stress

Ilya O. Velegzhaninov, Vitaliy A. Ievlev, Yana I. Pylina, Dmitry M. Shadrin, Olesya M. Vakhrusheva

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: cell programming; stress resistance; gene overexpression; radiation; oxidative stress; chemical genotoxins; malignant transformation; diversity of mechanisms

Online: 9 December 2017 (13:26:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints201804.0179.v1

Economic Diversity and the Resource Curse: A Dynamic Panel Model

Fred Olayele, Kwok Soo

Subject: Business, Economics And Management, Economics Keywords: Diversity; resource curse; economic growth.

Online: 13 April 2018 (14:18:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0678.v1

Time-Dependent Unitary Transformation Method in the Strong-Field-Ionization Regime With the Kramers-Henneberger Picture

Je Hoi Mun, Hirofumi Sakai, Dong Eon Kim

Subject: Physical Sciences, Acoustics Keywords: Time-dependent Schrödinger equation; Numerical method; Laser-matter interaction; Kramers-Henneberger; Time-dependent unitary transformation

Online: 28 June 2021 (15:27:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202101.0238.v1

Artificial Reefs in the North-East Atlantic Area: Present Situation, Knowledge Gaps and Future Perspectives

Bianca Reis, Pieter van der Linden, Isabel Sousa Pinto, Emanuel Almada, Maria Teresa Borges, Alice E. Hall, Rick Stafford, Roger J.H. Herbert, Jorge Lobo-Arteaga, Maria José Gaudêncio, Miriam Tuaty-Guerra, Océane Ly, Valentin Georges, Mariane Audo, Nassim Sebaibi, Mohamed Boutouil, Elena Blanco-Fernandez, João N. Franco

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Artificial reefs; design; building material; bio-monitoring; species diversity; European Atlantic

Online: 13 January 2021 (10:31:56 CET)

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Artificial reefs have been deployed in multiple regions of the world for different purposes including habitat restoration and protection, biodiversity and fish stock enhancement, fisheries management and recreation. Artificial reefs can be a valuable tool for ecosystem protection and rehabilitation, helping mitigate the effects of anthropogenic impacts that we face today. However, knowledge on artificial reefs is unevenly distributed worldwide, with some regions having much more quality information available and published (e.g. European Mediterranean Sea area), while others, for instance the North-East Atlantic area, do not. Here, we provide a characterization of purposely built artificial reefs in North-East Atlantic area based on all available literature (i.e. research papers and reports), highlighting the needs and gaps that are vital for establishing future perspectives for artificial reef deployment and research. In the North-East Atlantic area, sixty-one purposely built artificial reefs have been deployed since 1970, mostly between the years 1990-2009, with Spain being the country with the highest number of artificial reefs. The most reported purpose for their deployment is fisheries productivity and habitat/species protection, although, most artificial reefs are multipurpose in order to maximise the benefits of a given financial investment. The majority of artificial reefs were submerged at < 50 m, mainly between 10-20 m of depth. The most used designs were cubic blocks and complex designs made by an array of combined shapes, which mostly consist of concrete (79%). From all the analysed data on artificial reefs, 67% of the cases reported surveys to assess biodiversity after the deployment. However, in 26% of those cases, data was not available. When data was available, only 31% of cases reported long-term biomonitoring surveys (3 years or more). Based upon these findings, we noticed a general lack of scientifically robust data, including records of species and abundance of both fish and invertebrates, as well as macroalgae. Preventing an adequate determination of the best balance between shape, construction material and bio-colonization. Critiques and suggestions are discussed in the light of current available data in order to perform more efficient research, evaluation and functioning of future artificial reefs.

Preprint ARTICLE | doi:10.20944/preprints201802.0090.v1

High-throughput Sequencing Analysis of the Actinobacterial Apatial Diversity in Moonmilk Deposits

Marta Maciejewska, Magdalena Calusinska, Luc Cornet, Delphine Adam, Igor Pessi, Sandrine Malchair, Philippe Delfosse, Denis Baurain, Hazel Barton, Monique Carnol, Sébastien Rigali

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: antibiotics; geomicrobiology; Illumina sequencing; microbiome diversity; Streptomyces; Cave microbiology

Online: 12 February 2018 (16:30:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0109.v1

Effects of Altered Dietary Fiber on the Gut Microbiota, Short-Chain Fatty Acids and Cecum of Chickens during Different Growth Periods

Baosheng Sun, Linyue Hou, Yu Yang

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: dietary fiber; SCFA; growth period; chickens; gut microbiota; microbiotal diversity; age; cecum

Online: 9 February 2020 (16:24:29 CET)

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Increasing numbers of researchers are interested in the importance of dietary fiber for the gut microbiota, microbiotal metabolite SCFA, energy metabolism and gut health of the host. However, studies have demonstrated that long-term and longitudinal observation may be needed to evaluate the effect of dietary fiber better, and few such works have been made in chickens. Therefore, we successively fed low-fiber, high--fiber and low-fiber diets to two breeds of chickens during different growth periods (1—8, 9—20 and 21—50 weeks), aiming to longitudinally observe the long-term effect of altered dietary fiber on the gut microbiota, SCFA and development of cecum of chickens with age. The results showed that the composition and function of the gut microbiota, SCFA and the development of the cecum were different during different periods, which was largly affected by dietary fiber. However, the causes of some effects were different during the different periods. For example, compared with that in low-fiber chickens at 8 weeks, dominant fiber-degradation bacteria such as Bacteroidetes, Alloprevotella and SCFA-producing bacteria such as Faecalibacterium increased due to a high-fiber diet at 20 weeks, while due to a high feed intake in 50 weeks. Moreover, the concentration of SCFA in 20 weeks was significantly higher than in 8 weeks and 50 weeks, but the causes of this difference were also distinct. It was proposed that a long-term observation was needed to evaluate the effect of dietary fiber better on chickens. The metabolite pathways of ATP-binding cassette (ABC) transporters encoded by Firmicutes were enriched in 8 weeks, while a two-component system and β–glucosidase encoded by Bacteroidetes were enriched in 20 and 50 weeks. The trend was the same in two breeds of chickens except for Alloprevotella. In addition, the total content of SCFA in the contents of cecum was also affected by the size of the cecum. Surprisingly, the length of the cecum shortened from 20—50 weeks, maybe due to reduced dietary fiber.

Preprint REVIEW | doi:10.20944/preprints201712.0182.v4

Mitigating Challenges of Open Government Data

Nim Dvir

Subject: Computer Science And Mathematics, Information Systems Keywords: open access initiative; challenges of data sharing; data management; open government data; human-computer interaction; documentation; human factors; standardization; information policy

Online: 17 January 2018 (11:09:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0209.v1

UAV Remote Sensing for Biodiversity Monitoring: Are Forest Canopy Gaps Good Covariates?

Martin B. Bagaram, Diego Giuliarelli, Gherardo Chirici, Francesca Giannetti, Anna Barbati

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: Unmanned Aerial systems (UAS); , RGB high resolution imagery; forest canopy gaps; understorey; vertical species diversity; microhabitat-bearing trees; contrast split segmentation; drone

Online: 12 July 2018 (05:36:22 CEST)

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Forest canopy gaps are important for the ecosystem dynamics. Depending on tree species, small canopy openings might be also associated to intra-crown porosity and to space between crowns. Yet, little is known on the relationships between the fine-scaled pattern of canopy openings and biodiversity features. This research explored the possibility of i)- mapping forest canopy gaps from a very high resolution orthomosaic (10 cm), processed from a versatile imaging platform such as unmanned aerial vehicles (UAV), ii)- to derive patch metrics that can be tested as covariates of variables of interest for forest biodiversity monitoring. This is attempted in a test area of 240 ha covered by temperate deciduous forest types in Central Italy and containing 50 forest inventory plots of about 530 m². Correlation and linear regression techniques were used to explore relationships between patch metrics and understorey (density, development and species diversity) or forest habitat biodiversity variables (density of micro-habitat bearing trees, vertical species profile, tree species diversity). The results revealed that small openings in the canopy cover (75% smaller than 7 m²) can be faithfully extracted from UAV RGB imagery, using the red band and contrast split segmentation. Highest correlations were observed in the mixed forest (beech and turkey oak), while beech forest had the poorest ones and turkey oak forest displayed intermediate results. Moderate to strong linear relationships were found between gap metrics and understorey variables in mixed forest type, with adjusted R² from linear regression ranging from 0.52 to 0.87. Equally good results, in the same forest types, were observed for forest habitat biodiversity variables (0.52<adjusted R²<0.79) with highest values found for density of trees with microhabitats and vertical species profile. In conclusion, this research highlights that UAV remote sensing can potentially provide covariate surfaces of variables of interest for forest biodiversity monitoring, conventionally collected in forest inventory plots. By integrating the two sources of data, these variables can be mapped over small forest areas with satisfactory levels of accuracy, at a much higher spatial resolution than would be possible by field-based forest inventory solely.

Preprint ARTICLE | doi:10.20944/preprints202009.0029.v1

Risk of COVID-19 on Diabetes Mellitus and Hypertension

Abdullahi Aborode, Ademola Aiyenuro, Samuel Ogunsola, Victor Adesewa, Monsour Zakariyah

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: diabetes mellitus; hypertension; obesity; Coronavirus; mechanism; COVID-19; viral interaction

Online: 2 September 2020 (05:37:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201907.0051.v1

Identification of Biomarker Signatures and Candidate Drugs in Non-Small Cell Lung Cancer

Amina Rownaq, Md. Parvez Mosharaf, S. M. Shahinul Islam, Md. Nurul Haque Mollah

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: lung cancer; molecular signature; molecular pathway; differentially expressed genes; protein-protein interaction; reporter biomolecules and bioinformatics

Online: 3 July 2019 (08:54:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0144.v1

ISSR-Markers Assisted Genetic Diversity Assessment of Acid Lime [Citrus aurantifolia (Christm.) Swingle] Germplasm of Eastern Nepal

Nabin Narayan Munankarmi, Neesha Rana, Tribikram Bhattarai, Ram Lal Shrestha, Bal Krishna Joshi, Bikash Baral, Sangita Shrestha

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: citrus breeding; diversity; genetic similarity; Lime; molecular markers; PCR

Online: 9 May 2018 (11:05:37 CEST)

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Acid lime [Citrus aurantifolia (Christm.) Swingle] is a fruit crop, enriched with high commercial value and is cultivated in 60 out of 75 districts representing all geographical landscapes of Nepal. Lack of high yielding cultivars is probably one of the main reason for its extremely reduced productivity which warrants a deep understanding of genetic diversity in existing germplasm. Hereby, we aim to access the genetic diversity of acid lime germplasm cultivated at 3-different ecological gradients of eastern Nepal employing PCR-based Inter-Simple Sequence Repeats markers (ISSR). Altogether, 21 polymorphic ISSR markers were used to assess the genetic diversity in 60 acid lime cultivars sampled from different geographical locations. Analysis of binary data matrix was performed on the basis of bands obtained, scoring of the data was done accordingly, and principal coordinate analysis and phenogram were constructed using different computer algorithms. ISSR profiling yielded 234 amplicons, of which 87.18% were found to be polymorphic. The number of amplified fragments ranged from 7-18 with amplicon size ranging from 250-3200 bp. The NTSYS based Cluster analysis using UPGMA algorithm taking Dice Similarity coefficient separated 60 accessions into 2-major and 3-minor clusters. The genetic diversity analysis revealed the highest for Terai and the lowest for High-hill zone. Cluster I comprised of accessions from High-hill and Mid-hill regions revealing the close genetic relationship, whereas cluster II comprised of accessions from all three agro-ecological zones and the exotic varieties. Furthermore, our results revealed the accessions harvested from different geographical gradients were not genetically distinct, but highest diversity was observed in Terai accessions in comparison to the regions belonging to the High and Mid-hills. Thus, our data indicate that the ISSR provides a better option for evaluating the genetic diversity of Nepalese Acid Lime cultivars and furnished significant information, assisting parental selection in current and future breeding programs and germplasm conservation which ultimately may help to provide a technological breakthrough for the farmers of the developing country like Nepal.

Preprint ARTICLE | doi:10.20944/preprints201811.0627.v1

BIOFACQUIM: A Mexican Compound Database of Natural Products

B. Angélica Pilón-Jiménez, Fernanda I. Saldívar-González, Bárbara I. Díaz-Eufracio, José L. Medina-Franco

Subject: Chemistry And Materials Science, Theoretical Chemistry Keywords: chemical space; chemical data set; chemoinformatics; consensus diversity plot; drug discovery; molecular diversity; visualization

Online: 30 November 2018 (10:06:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints201812.0324.v1

Gesture-Based Control of a Robot Arm with Neuromorphic Haptic Feedback

Francesca Sorgini, Giuseppe Airò Farulla, Nikola Lukic, Ivan Danilov, Bozica Bojovic, Milos Milivojevic, Terrin Babu Pulikottil, Loris Roveda, Paolo Prinetto, Tullio Tolio, Maria Chiara Carrozza, Petar Petrovic, Calogero Maria Oddo

Subject: Engineering, Control And Systems Engineering Keywords: telepresence; neuromorphic vibrotactile feedback; human-robot interaction; hand tracking; gesture-based teleoperation

Online: 28 December 2018 (03:53:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints201803.0120.v1

Molecular Diversity of The Tidal Swamp Rice (Oryza sativa L.) Germplasm of The South Kalimantan, Indonesia

Dindin H. Mursyidin, Purnomo Purnomo, Issirep Sumardi, Budi S. Daryono

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Oryza sativa; genetic diversity; tidal swamp; breeding and conservation programs

Online: 15 March 2018 (06:50:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints201910.0209.v1

Agronomic Practices, Genetic Diversity and Population Structure of Moringa oleifera (Lam.) in Nigeria

Jacob Popoola, David Igwe, Opeyemi Jegede, Victoria Iwu, Adegoke Adegbite, Conrad Omonhinmin

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: agronomic practices; agrobiodiversity; aflp; climate change; cluster analysis; genetic diversity; moringa oleifera; food and nutrition security

Online: 18 October 2019 (07:34:50 CEST)

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Evaluation of agronomic practices, genetic diversity and population structure of Moringa oleifera (Lam.) is crucial to its sustainable utilization to ensure food and nutritional security. Four agronomic practices of field preparation and soil analysis, regeneration, weeding and pruning, as well as harvesting, were adopted. Genetic diversity and population structure of 20 populations were evaluated using amplified fragment length polymorphism (AFLP) primer pairs (E-ACC/M-CAC and E-ACA/M-CAG). The effects of agronomic practices on leaf quantity production were evaluated using standard procedures. The physico-chemical and morphological data were analyzed using descriptive statistics, while genetic diversity, population structure, dendrogram reconstruction, and Principal Component Analysis (PCA) were analyzed from the AFLP genetic data. Significant effects (P ≤ 0.05) of agronomic practices on the quantity of leaf production were recorded across the accessions. The two primer pairs generated a total of 80 alleles with a mean major allele frequency of 0.0250. Gene diversity and polymorphic information content (PIC) values were high with a mean of 0.98 and 0.974, respectively. The Gst value of 0.0490 indicated that 5 % of the total genetic divergence was among the population while 95 % within the population. Dendrogram reconstruction with genetic distance ranging from 0.87 to 0.96 segregated the accessions into eleven clusters while PCA generated six cluster groups. Field preparation and physico-chemical soil properties, regeneration, weeding and pruning, and stand development, as well as harvesting, influenced the leaf yield and genetic diversity observed in this study. The genetic data revealed that some accessions were clustered along eco-geographical lines while others grouped disparately. Identified potential parent genotypes with valuable and desirable genetic traits can be exploited for commercial, breeding and conservation purposes to ensure sustainable utilization of the species in Nigeria.

Preprint ARTICLE | doi:10.20944/preprints201808.0426.v2

Cities, from Information to Interaction

Vinicius M. Netto, Edgardo Brigatti, João Meirelles, Fabiano L. Ribeiro, Bruno Pace, Caio Cacholas, Patricia Sanches

Subject: Social Sciences, Urban Studies And Planning Keywords: information; cities; interaction; environmental information; entropy; scale; enaction

Online: 10 October 2018 (05:32:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202101.0614.v1

Unlocking the Patterns of the Tunisian Durum Wheat Landraces Genetic Structure Based on Phenotypic Characterization in Relation to Farmer’s Vernacular Name

Cyrine Robbana, Zakaria Kehel, Karim Ammar, Carlos Guzmán, M’Barek Ben Naceur, Ahmed Amri

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Durum wheat; Tunisian landraces; genetic diversity; population structure; phenotypic characterization

Online: 29 January 2021 (11:53:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202302.0386.v1

A Cost-Effective Immobilization Method of MBP-Fusion Proteins on Microtiter Plates Using a Gelatinized Starch-Agarose Mixture and Its Application for Convenient Protein–Protein Interaction Analysis

Yuri Emoto, Ryoya Katayama, Emi Hibino, Sho Ishihara, Natsuko Goda, Takeshi Tenno, Yoshihiro Kobashigawa, Hiroshi Morioka, Hidekazu Hiroaki

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: gelatinized starch; maltose-binding protein; microplate based assay; protein-protein interaction; dissociation constant determination

Online: 22 February 2023 (14:53:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints201712.0012.v1

Construction and Experimental Study of a 3-Dof Haptic Master for Interactive Operation

Huijun Li, Aiguo Song, Baoguo Xu, Bowei Li, Hong Zeng, Zhen Lin

Subject: Engineering, Mechanical Engineering Keywords: haptic master; force feedback; VR- based interaction; ergonomics assessments

Online: 3 December 2017 (06:02:50 CET)

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Preprint ESSAY | doi:10.20944/preprints202003.0152.v1

Let's Stream! A Beginners' Guide to Live-Streaming Scientific Conferences

C. Eduardo Guerra Amorim, Serena Tucci

Subject: Social Sciences, Media Studies Keywords: live-streaming; video-conference; broadcast; scientific conferences; diversity; inclusion

Online: 10 March 2020 (02:29:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints201910.0155.v1

A Function-as-a-Service Based Fog Robotic System for Cognitive Robots

Hyunsik Ahn

Subject: Engineering, Control And Systems Engineering Keywords: robot cloud; cognition as a service; cognitive robots; sentential cognitive system; cloud service; human–robot interaction

Online: 14 October 2019 (06:26:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201708.0031.v1

Detection of Aβ(1-40) Protein in Human Serum as A Causative Agent of Alzheimer’s Disease by Strain Gauge Cantilever Biosensor Immobilizing Liposome Incorporating Cholesterol

Tomoya Taniguchi, Yuki Murakami , Masayuki Sohgawa , Kaoru Yamashita, Minoru Noda

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: cantilever; NiCr strain gauge; biosensor; liposome; amyloid beta; aggregation; fibrillization; interaction; human serum; digital low-pass filtering procedure

Online: 8 August 2017 (09:57:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201909.0278.v1

Simulation of Air Puff Tonometry Test Using Arbitrary Lagrangian-Eulerian (ALE) Deforming Mesh for Corneal Material Characterisation

Osama Maklad, Ashkan Eliasy, Kai-Jung Chen, Vassilios Theofilis, Ahmed Elsheikh

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: ocular biomechanics; intraocular pressure (iop); fluid structure interaction (fsi); arbitrary lagrangian-eulerian mesh (ale)

Online: 25 September 2019 (08:16:34 CEST)

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